G-418 (BioDeep_00000011838)

   


代谢物信息卡片


(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol

化学式: C20H40N4O10 (496.27443000000005)
中文名称: G-418 硫酸盐
谱图信息: 最多检出来源 Macaca mulatta(otcml) 0.07%

分子结构信息

SMILES: CC(C1C(C(C(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)O)O)O
InChI: InChI=1S/C20H40N4O10/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19/h6-19,24-30H,4-5,21-23H2,1-3H3/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+/m1/s1

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D005839 - Gentamicins

同义名列表

7 个代谢物同义名

(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; Antibiotic G-418; CHEMBL2008763; Geneticin; G-418; g418; Antibiotic G-418



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sivan Louzoun Zada, Bar Ben Baruch, Luba Simhaev, Hamutal Engel, Micha Fridman. Chemical Modifications Reduce Auditory Cell Damage Induced by Aminoglycoside Antibiotics. Journal of the American Chemical Society. 2020 02; 142(6):3077-3087. doi: 10.1021/jacs.9b12420. [PMID: 31958945]
  • Amnon Wittenstein, Michal Caspi, Yifat David, Yamit Shorer, Prathamesh T Nadar-Ponniah, Rina Rosin-Arbesfeld. Serum starvation enhances nonsense mutation readthrough. Journal of molecular medicine (Berlin, Germany). 2019 12; 97(12):1695-1710. doi: 10.1007/s00109-019-01847-0. [PMID: 31786671]
  • Edouard Evangelisti, Temur Yunusov, Liron Shenhav, Sebastian Schornack. N-acetyltransferase AAC(3)-I confers gentamicin resistance to Phytophthora palmivora and Phytophthora infestans. BMC microbiology. 2019 11; 19(1):265. doi: 10.1186/s12866-019-1642-0. [PMID: 31775609]
  • Imran Rashid Rajput, Ziyang Xiao, Sun Yajing, Summra Yaqoob, Edmond Sanganyado, Huang Ying, Yu Fei, Wenhua Liu. Establishment of pantropic spotted dolphin (Stenella attenuata) fibroblast cell line and potential influence of polybrominated diphenyl ethers (PBDEs) on cytokines response. Aquatic toxicology (Amsterdam, Netherlands). 2018 Oct; 203(?):1-9. doi: 10.1016/j.aquatox.2018.07.017. [PMID: 30064049]
  • Jorge Morales, Sofia Kokkori, Diana Weidauer, Jarrod Chapman, Eugene Goltsman, Daniel Rokhsar, Arthur R Grossman, Eva C M Nowack. Development of a toolbox to dissect host-endosymbiont interactions and protein trafficking in the trypanosomatid Angomonas deanei. BMC evolutionary biology. 2016 11; 16(1):247. doi: 10.1186/s12862-016-0820-z. [PMID: 27835948]
  • Ayako Nishizawa-Yokoi, Satoko Nonaka, Keishi Osakabe, Hiroaki Saika, Seiichi Toki. A Universal Positive-Negative Selection System for Gene Targeting in Plants Combining an Antibiotic Resistance Gene and Its Antisense RNA. Plant physiology. 2015 Sep; 169(1):362-70. doi: 10.1104/pp.15.00638. [PMID: 26143254]
  • Kimitsune Ishizaki, Ryuichi Nishihama, Minoru Ueda, Keisuke Inoue, Sakiko Ishida, Yoshiki Nishimura, Toshiharu Shikanai, Takayuki Kohchi. Development of Gateway Binary Vector Series with Four Different Selection Markers for the Liverwort Marchantia polymorpha. PloS one. 2015; 10(9):e0138876. doi: 10.1371/journal.pone.0138876. [PMID: 26406247]
  • Willian J Andrioli, Raphael Conti, Magali J Araújo, Riccardo Zanasi, Bruno C Cavalcanti, Viviane Manfrim, Juliano S Toledo, Daniele Tedesco, Manoel O de Moraes, Cláudia Pessoa, Angela K Cruz, Carlo Bertucci, José Sabino, Dhammika N P Nanayakkara, Mônica T Pupo, Jairo K Bastos. Mycoleptones A-C and polyketides from the endophyte Mycoleptodiscus indicus. Journal of natural products. 2014 Jan; 77(1):70-8. doi: 10.1021/np4006822. [PMID: 24387625]
  • Markus Thiel, Annette Lis, Reinhold Penner. STIM2 drives Ca2+ oscillations through store-operated Ca2+ entry caused by mild store depletion. The Journal of physiology. 2013 Mar; 591(6):1433-45. doi: 10.1113/jphysiol.2012.245399. [PMID: 23359669]
  • Sabine Gruber, Markus Omann, Carolina Escobar Rodrìguez, Theresa Radebner, Susanne Zeilinger. Generation of Trichoderma atroviride mutants with constitutively activated G protein signaling by using geneticin resistance as selection marker. BMC research notes. 2012 Nov; 5(?):641. doi: 10.1186/1756-0500-5-641. [PMID: 23158850]
  • Rachel Zufferey, Stergios S Bibis, Tongtong Zhu, Subbhalakshmi Dhalladoo. Characterization of a compensatory mutant of Leishmania major that lacks ether lipids but exhibits normal growth, and G418 and hygromycin resistance. Experimental parasitology. 2012 Mar; 130(3):200-4. doi: 10.1016/j.exppara.2012.01.008. [PMID: 22306069]
  • Gabriel Rinaldi, Sutas Suttiprapa, José F Tort, Anne E Folley, Danielle E Skinner, Paul J Brindley. An antibiotic selection marker for schistosome transgenesis. International journal for parasitology. 2012 Jan; 42(1):123-30. doi: 10.1016/j.ijpara.2011.11.005. [PMID: 22155152]
  • Sousuke Imamura, Daisuke Hagiwara, Fumi Suzuki, Norihide Kurano, Shigeaki Harayama. Genetic transformation of Pseudochoricystis ellipsoidea, an aliphatic hydrocarbon-producing green alga. The Journal of general and applied microbiology. 2012; 58(1):1-10. doi: 10.2323/jgam.58.1. [PMID: 22449745]
  • Jiri Aubrecht, Mary E P Goad, Agnieszka K Czopik, Charles P Lerner, Kevin A Johnson, Elizabeth M Simpson, Robert H Schiestl. A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro. Drug and chemical toxicology. 2011 Oct; 34(4):433-9. doi: 10.3109/01480545.2010.544316. [PMID: 21740348]
  • Patricia K Dranchak, Erminia Di Pietro, Ann Snowden, Nathan Oesch, Nancy E Braverman, Steven J Steinberg, Joseph G Hacia. Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations. Journal of cellular biochemistry. 2011 May; 112(5):1250-8. doi: 10.1002/jcb.22979. [PMID: 21465523]
  • Jian Yao, Tao Huang, Xin Fang, Yuan Chi, Ying Zhu, Yigang Wan, Hiroyuki Matsue, Masanori Kitamura. Disruption of gap junctions attenuates aminoglycoside-elicited renal tubular cell injury. British journal of pharmacology. 2010 Aug; 160(8):2055-68. doi: 10.1111/j.1476-5381.2010.00860.x. [PMID: 20649601]
  • Dirk Theile, Bianca Staffen, Johanna Weiss. ATP-binding cassette transporters as pitfalls in selection of transgenic cells. Analytical biochemistry. 2010 Apr; 399(2):246-50. doi: 10.1016/j.ab.2009.12.014. [PMID: 20018165]
  • Hidenobu Uchida, Hirofumi Yamashita, Toyoaki Anai, Toshiya Muranaka, Kanji Ohyama. Agrobacterium-mediated transformation of Euphorbia tirucalli callus. Bioscience, biotechnology, and biochemistry. 2010; 74(4):851-3. doi: 10.1271/bbb.90783. [PMID: 20445322]
  • Sarah Conte, David Stevenson, Ian Furner, Alan Lloyd. Multiple antibiotic resistance in Arabidopsis is conferred by mutations in a chloroplast-localized transport protein. Plant physiology. 2009 Oct; 151(2):559-73. doi: 10.1104/pp.109.143487. [PMID: 19675150]
  • Xiaofei Wang, Robert F Newkirk, Wilfrid Carre, Purnima Ghose, Barry Igobudia, James G Townsel, Larry A Cogburn. Regulation of ANKRD9 expression by lipid metabolic perturbations. BMB reports. 2009 Sep; 42(9):568-73. doi: 10.5483/bmbrep.2009.42.9.568. [PMID: 19788857]
  • Terézia Salaj, Jana Moravcíková, Bozena Vooková, Ján Salaj. Agrobacterium-mediated transformation of embryogenic tissues of hybrid firs (Abies spp.) and regeneration of transgenic emblings. Biotechnology letters. 2009 May; 31(5):647-52. doi: 10.1007/s10529-009-9923-6. [PMID: 19169892]
  • Spencer S Ericksen, David F Cummings, Harel Weinstein, John A Schetz. Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding. The Journal of pharmacology and experimental therapeutics. 2009 Jan; 328(1):40-54. doi: 10.1124/jpet.108.141531. [PMID: 18849360]
  • Rustam Azimov, Natalia Abuladze, Pakan Sassani, Debra Newman, Liyo Kao, Weixin Liu, Nicholas Orozco, Piotr Ruchala, Alexander Pushkin, Ira Kurtz. G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. American journal of physiology. Renal physiology. 2008 Sep; 295(3):F633-41. doi: 10.1152/ajprenal.00015.2008. [PMID: 18614622]
  • Paulina Rosas-Arreguín, Pablo Arteaga-Nieto, Ramón Reynoso-Orozco, Julio C Villagómez-Castro, Myrna Sabanero-López, Ana M Puebla-Pérez, Carlos Calvo-Méndez. Bursera fagaroides, effect of an ethanolic extract on ornithine decarboxylase (ODC) activity in vitro and on the growth of Entamoeba histolytica. Experimental parasitology. 2008 Jul; 119(3):398-402. doi: 10.1016/j.exppara.2008.04.003. [PMID: 18501354]
  • Alexander V Birk, Edward J Dubovi, Xianchao Zhang, Hazel H Szeto. Antiviral activity of geneticin against bovine viral diarrhoea virus. Antiviral chemistry & chemotherapy. 2008; 19(1):33-40. doi: 10.1177/095632020801900105. [PMID: 18610556]
  • Zi-Xuan Wang, Zi-Li Yi, Zhi-Cheng Wang, Jian-Xiong Jiang, Jing-Ping Qin, Hao Zhang, Yan-Ning Tan. [Quick testing-technology of transgenic rice with npt- screen marker gene]. Yi chuan = Hereditas. 2007 Apr; 29(4):499-507. doi: 10.1360/yc-007-0499. [PMID: 17548315]
  • Selina Gastmann, Alexander Dünkler, Andrea Walther, Keith Klein, Jürgen Wendland. A molecular toolbox for manipulating Eremothecium coryli. Microbiological research. 2007; 162(4):299-307. doi: 10.1016/j.micres.2007.05.008. [PMID: 17716882]
  • Jill M Schroeder, Hend Ibrahim, Lynn Taylor, Norman P Curthoys. Role of deadenylation and AUF1 binding in the pH-responsive stabilization of glutaminase mRNA. American journal of physiology. Renal physiology. 2006 Mar; 290(3):F733-40. doi: 10.1152/ajprenal.00250.2005. [PMID: 16219914]
  • Ergeng Hao, Björn Tyrberg, Pamela Itkin-Ansari, Jonathan R T Lakey, Ifat Geron, Edward Z Monosov, Maria Barcova, Mark Mercola, Fred Levine. Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nature medicine. 2006 Mar; 12(3):310-6. doi: 10.1038/nm1367. [PMID: 16491084]
  • Colin Eady, Sheree Davis, Andrew Catanach, Fernand Kenel, Sarah Hunger. Agrobacterium tumefaciens-mediated transformation of leek (Allium porrum) and garlic (Allium sativum). Plant cell reports. 2005 Jun; 24(4):209-15. doi: 10.1007/s00299-005-0926-z. [PMID: 15789208]
  • Wen-Yuan Zhu, Ru-Zhi Zhang, Hui-Jun Ma, Da-Guang Wang. Isolation and culture of amelanotic melanocytes from human hair follicles. Pigment cell research. 2004 Dec; 17(6):668-73. doi: 10.1111/j.1600-0749.2004.00190.x. [PMID: 15541025]
  • Victorine Douin, Stephanie Bornes, Laurent Creancier, Philippe Rochaix, Gilles Favre, Anne-Catherine Prats, Bettina Couderc. Use and comparison of different internal ribosomal entry sites (IRES) in tricistronic retroviral vectors. BMC biotechnology. 2004 Jul; 4(?):16. doi: 10.1186/1472-6750-4-16. [PMID: 15279677]
  • Q H Jin, B Zhao, X J Zhang. Cytochrome c release and endoplasmic reticulum stress are involved in caspase-dependent apoptosis induced by G418. Cellular and molecular life sciences : CMLS. 2004 Jul; 61(14):1816-25. doi: 10.1007/s00018-004-4143-7. [PMID: 15241557]
  • Katrin Sangkuhl, Angela Schulz, Holger Römpler, June Yun, Jürgen Wess, Torsten Schöneberg. Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo. Human molecular genetics. 2004 May; 13(9):893-903. doi: 10.1093/hmg/ddh105. [PMID: 14998935]
  • D Schade, A Walther, J Wendland. The development of a transformation system for the dimorphic plant pathogen Holleya sinecauda based on Ashbya gossypii DNA elements. Fungal genetics and biology : FG & B. 2003 Oct; 40(1):65-71. doi: 10.1016/s1087-1845(03)00064-1. [PMID: 12948514]
  • Melanie Peters, Saskia Ermert, Nikola Jeck, Christian Derst, Ulla Pechmann, Stefanie Weber, Karl P Schlingmann, Hannsjoerg W Seyberth, Siegfried Waldegger, Martin Konrad. Classification and rescue of ROMK mutations underlying hyperprostaglandin E syndrome/antenatal Bartter syndrome. Kidney international. 2003 Sep; 64(3):923-32. doi: 10.1046/j.1523-1755.2003.00153.x. [PMID: 12911542]
  • Monica Hajdena-Dawson, Weisheng Zhang, Pamela R Contag, Ronald J Wong, Hendrik J Vreman, David K Stevenson, Christopher H Contag. Effects of metalloporphyrins on heme oxygenase-1 transcription: correlative cell culture assays guide in vivo imaging. Molecular imaging. 2003 Jul; 2(3):138-49. doi: 10.1162/15353500200303139. [PMID: 14649057]
  • George Hoppe, Yuh Cherng Chai, Jonathan Sears. Endogenous oxidoreductase expression is induced by aminoglycosides. Archives of biochemistry and biophysics. 2003 Jun; 414(1):19-23. doi: 10.1016/s0003-9861(03)00144-9. [PMID: 12745250]
  • Chunnuan Chen, Yu Liang Huang, Shang-Tian Yang. A fibrous-bed bioreactor for continuous production of developmental endothelial locus-1 by osteosarcoma cells. Journal of biotechnology. 2002 Jul; 97(1):23-39. doi: 10.1016/s0168-1656(02)00053-6. [PMID: 12052680]
  • M C Rice, M Bruner, K Czymmek, E B Kmiec. In vitro and in vivo nucleotide exchange directed by chimeric RNA/DNA oligonucleotides in Saccharomyces cerevisae. Molecular microbiology. 2001 May; 40(4):857-68. doi: 10.1046/j.1365-2958.2001.02407.x. [PMID: 11401693]
  • F Shiraishi, G A Visner, H S Nick, A Agarwal. Geneticin induces endogenous heme oxygenase-1 expression: implication in transfection studies. Analytical biochemistry. 2001 Feb; 289(2):303-5. doi: 10.1006/abio.2000.4965. [PMID: 11161329]
  • S F Aliño, E Escrig, F Revert, V M Guillem, A Crespo. Pharmacodynamic approach to study the gene transfer process employing non-viral vectors. Biochemical pharmacology. 2000 Dec; 60(12):1845-53. doi: 10.1016/s0006-2952(00)00503-7. [PMID: 11108800]
  • B T Tey, R P Singh, L Piredda, M Piacentini, M Al-Rubeai. Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody. Biotechnology and bioengineering. 2000 Apr; 68(1):31-43. doi: 10.1002/(sici)1097-0290(20000405)68:1<31::aid-bit4>3.0.co;2-l. [PMID: 10699869]
  • M Kojic, W K Holloman. Shuttle vectors for genetic manipulations in Ustilago maydis. Canadian journal of microbiology. 2000 Apr; 46(4):333-8. doi: 10.1139/w00-002. [PMID: 10779869]
  • K Strutzenberger, N Borth, R Kunert, W Steinfellner, H Katinger. Changes during subclone development and ageing of human antibody-producing recombinant CHO cells. Journal of biotechnology. 1999 Apr; 69(2-3):215-26. doi: 10.1016/s0168-1656(99)00044-9. [PMID: 10361728]
  • P J Gatti, B Choi, A M Haislip, C D Fermin, R F Garry. Inhibition of HIV type 1 production by hygromycin B. AIDS research and human retroviruses. 1998 Jul; 14(10):885-92. doi: 10.1089/aid.1998.14.885. [PMID: 9671217]
  • B O Oyajobi, A Frazer, A P Hollander, R M Graveley, C Xu, A Houghton, P V Hatton, R G Russell, B M Stringer. Expression of type X collagen and matrix calcification in three-dimensional cultures of immortalized temperature-sensitive chondrocytes derived from adult human articular cartilage. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 1998 Mar; 13(3):432-42. doi: 10.1359/jbmr.1998.13.3.432. [PMID: 9525344]
  • A N Gubin, B Reddy, J M Njoroge, J L Miller. Long-term, stable expression of green fluorescent protein in mammalian cells. Biochemical and biophysical research communications. 1997 Jul; 236(2):347-50. doi: 10.1006/bbrc.1997.6963. [PMID: 9240438]
  • C Bethune, T Bui, M L Liu, M A Kay, R J Ho. Development of a high-performance liquid chromatographic assay for G418 sulfate (Geneticin). Antimicrobial agents and chemotherapy. 1997 Mar; 41(3):661-4. doi: 10.1128/aac.41.3.661. [PMID: 9056010]
  • A Artishevsky, D R Cha, S Adler, C C Nast, S Feld, R J Glassock, S G Adler. The effect of transfection of antisense cDNA for procollagen alpha 1 (IV) on stimulated proliferation in rat glomerular endothelial cells. Journal of the American Society of Nephrology : JASN. 1997 Jan; 8(1):61-9. doi: 10.1681/asn.v8161. [PMID: 9013449]
  • T Horikawa, D A Norris, T Zekman, J G Morelli. Effective elimination of fibroblasts in cultures of melanocytes by lowering calcium concentration in TPA depleted medium following geneticin treatment. Pigment cell research. 1996 Apr; 9(2):58-62. doi: 10.1111/j.1600-0749.1996.tb00089.x. [PMID: 8857666]
  • Z Chen, P Kamath, S Zhang, L St John, K Adler-Storthz, E J Shillitoe. Effects on tumor cells of ribozymes that cleave the RNA transcripts of human papillomavirus type 18. Cancer gene therapy. 1996 Jan; 3(1):18-23. doi: NULL. [PMID: 8785706]
  • J C Morris, P Lei, T Y Shen, K Mensa-Wilmot. Glycan requirements of glycosylphosphatidylinositol phospholipase C from Trypanosoma brucei. Glucosaminylinositol derivatives inhibit phosphatidylinositol phospholipase C. The Journal of biological chemistry. 1995 Feb; 270(6):2517-24. doi: 10.1074/jbc.270.6.2517. [PMID: 7852313]
  • T Niidome, T Teramoto, Y Murata, I Tanaka, T Seto, K Sawada, Y Mori, K Katayama. Stable expression of the neuronal BI (class A) calcium channel in baby hamster kidney cells. Biochemical and biophysical research communications. 1994 Sep; 203(3):1821-7. doi: 10.1006/bbrc.1994.2399. [PMID: 7945334]
  • M Takano, M Okuda, M Yasuhara, R Hori. Cellular toxicity of aminoglycoside antibiotics in G418-sensitive and -resistant LLC-PK1 cells. Pharmaceutical research. 1994 May; 11(5):609-15. doi: 10.1023/a:1018999423464. [PMID: 8058626]
  • D N Hu, S A McCormick, R Ritch, K Pelton-Henrion. Studies of human uveal melanocytes in vitro: isolation, purification and cultivation of human uveal melanocytes. Investigative ophthalmology & visual science. 1993 Jun; 34(7):2210-9. doi: . [PMID: 8505203]
  • M T Chan, H H Chang, S L Ho, W F Tong, S M Yu. Agrobacterium-mediated production of transgenic rice plants expressing a chimeric alpha-amylase promoter/beta-glucuronidase gene. Plant molecular biology. 1993 Jun; 22(3):491-506. doi: 10.1007/bf00015978. [PMID: 8392395]
  • T Inagaki, S Matsuwari, K Shimada, N Abe, R Takahashi, S Maeda. [Effective removal of the contaminating host fibroblasts for establishment of human-tumor cultured lines]. Human cell. 1993 Jun; 6(2):137-42. doi: NULL. [PMID: 8217952]
  • S R Pai, R C Bird. Growth of HeLa S3 cells cotransfected with plasmids containing a c-fos gene under the control of the SV40 promoter complex, pRSVcat, and G418 resistance. Biochemistry and cell biology = Biochimie et biologie cellulaire. 1992 May; 70(5):316-23. doi: 10.1139/o92-049. [PMID: 1323304]
  • E Ogris, I Mudrak, E Wintersberger. Polyomavirus large and small T antigens cooperate in induction of the S phase in serum-starved 3T3 mouse fibroblasts. Journal of virology. 1992 Jan; 66(1):53-61. doi: 10.1128/jvi.66.1.53-61.1992. [PMID: 1309261]
  • M W Bevan, R B Flavell, M D Chilton. A chimaeric antibiotic resistance gene as a selectable marker for plant cell transformation. 1983. Biotechnology (Reading, Mass.). 1992; 24(?):367-70. doi: ". [PMID: 1422041]
  • H S Judelson, B M Tyler, R W Michelmore. Transformation of the oomycete pathogen, Phytophthora infestans. Molecular plant-microbe interactions : MPMI. 1991 Nov; 4(6):602-7. doi: 10.1094/mpmi-4-602. [PMID: 1804404]
  • F X McCormack, J H Fisher, A Suwabe, D L Smith, J M Shannon, D R Voelker. Expression and characterization of rat surfactant protein A synthesized in Chinese hamster ovary cells. Biochimica et biophysica acta. 1990 Oct; 1087(2):190-8. doi: 10.1016/0167-4781(90)90204-f. [PMID: 2171680]
  • K Paludan, M Duch, P Jørgensen, N O Kjeldgaard, F S Pedersen. Graduated resistance to G418 leads to differential selection of cultured mammalian cells expressing the neo gene. Gene. 1989 Dec; 85(2):421-6. doi: 10.1016/0378-1119(89)90435-6. [PMID: 2560757]
  • H Gmünder, J Kohli. Cauliflower mosaic virus promoters direct efficient expression of a bacterial G418 resistance gene in Schizosaccharomyces pombe. Molecular & general genetics : MGG. 1989 Dec; 220(1):95-101. doi: 10.1007/bf00260862. [PMID: 2558289]
  • E T Marek, C L Schardl, D A Smith. Molecular transformation of Fusarium solani with an antibiotic resistance marker having no fungal DNA homology. Current genetics. 1989 Jun; 15(6):421-8. doi: 10.1007/bf00376799. [PMID: 2550150]
  • D Gupta, A Tartakoff, E Tisdale. Metabolic correction of defects in the lipid anchoring of Thy-1 in lymphoma mutants. Science (New York, N.Y.). 1988 Dec; 242(4884):1446-8. doi: 10.1126/science.2904699. [PMID: 2904699]
  • E Mendelson, M G Smith, B J Carter. Expression and rescue of a nonselected marker from an integrated AAV vector. Virology. 1988 Sep; 166(1):154-65. doi: 10.1016/0042-6822(88)90157-2. [PMID: 2842941]
  • F D Ledley, G J Darlington, T Hahn, S L Woo. Retroviral gene transfer into primary hepatocytes: implications for genetic therapy of liver-specific functions. Proceedings of the National Academy of Sciences of the United States of America. 1987 Aug; 84(15):5335-9. doi: 10.1073/pnas.84.15.5335. [PMID: 3474659]
  • D M Scott, C MacDonald, H Brzeski, R Kinne. Maintenance of expression of differentiated function of kidney cells following transformation by SV40 early region DNA. Experimental cell research. 1986 Oct; 166(2):391-8. doi: 10.1016/0014-4827(86)90485-4. [PMID: 2427348]
  • D A Spandidos, M Riggio. Polyoma virus middle T gene can trigger malignant transformation of early passage rodent cells. The Journal of general virology. 1986 Apr; 67 ( Pt 4)(?):793-9. doi: 10.1099/0022-1317-67-4-793. [PMID: 3007666]
  • J F Burke, A E Mogg. Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin. Nucleic acids research. 1985 Sep; 13(17):6265-72. doi: 10.1093/nar/13.17.6265. [PMID: 2995924]
  • C A Franke, C M Rice, J H Strauss, D E Hruby. Neomycin resistance as a dominant selectable marker for selection and isolation of vaccinia virus recombinants. Molecular and cellular biology. 1985 Aug; 5(8):1918-24. doi: 10.1128/mcb.5.8.1918-1924.1985. [PMID: 3018537]
  • C J Panchal, G K Whitney, G G Stewart. Susceptibility of Saccharomyces spp. and Schwanniomyces spp. to the aminoglycoside antibiotic G418. Applied and environmental microbiology. 1984 May; 47(5):1164-6. doi: 10.1128/aem.47.5.1164-1166.1984. [PMID: 6378088]
  • D Ursic, J D Kemp, J P Helgeson. A new antibiotic with known resistance factors, G418, inhibits plant cells. Biochemical and biophysical research communications. 1981 Aug; 101(3):1031-7. doi: 10.1016/0006-291x(81)91852-0. [PMID: 7306106]
  • H Beck, K Sack. [Experimental study on the renal compatibility of the aminoglycosides gentamicin B and O-2-amino-2-deoxy-6-C-methyl-alpha-D-glucopyranosyl-(1 greater than 4)-garamine (G-418)]. Arzneimittel-Forschung. 1979; 29(11):1695-700. doi: NULL. [PMID: 543878]