Allantoin (BioDeep_00000000111)

 

Secondary id: BioDeep_00000400042

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Chemicals and Drugs


代谢物信息卡片


(2,5-dioxoimidazolidin-4-yl)urea

化学式: C4H6N4O3 (158.0439886)
中文名称: 尿囊素
谱图信息: 最多检出来源 Viridiplantae(plant) 0.07%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Allantoin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/allantoin (retrieved 2024-11-03) (BioDeep RN: BioDeep_00000000111). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1(C(=O)NC(=O)N1)NC(=O)N
InChI: InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)

描述信息

Allantoin is an imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen. It has a role as a vulnerary, a human metabolite, a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite. It is a member of ureas and an imidazolidine-2,4-dione. It is functionally related to a hydantoin. It is a tautomer of a 1-(5-hydroxy-2-oxo-2,3-dihydroimidazol-4-yl)urea.
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated. In human muscle, urate is oxidized to allantoin during such exercise. The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise. More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid. It is a major metabolic intermediate in most organisms. Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions. Allantoin has also demonstrated to ameliorate the wound healing process in some studies.
Allantoin is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Allantoin is a natural product found in Aristolochia gigantea, Rhinacanthus, and other organisms with data available.
Allantoin is a mineral with formula of C4H6N4O3. The corresponding IMA (International Mineralogical Association) number is IMA2020-004a. The IMA symbol is Aan.
Allantoin is a diureide of glyoxylic acid with the chemical formula C4H6N4O3. It is also called 5-ureidohydantoin, glyoxyldiureide, and 5-ureidohydantoin. It is a product of oxidation of uric acid. It is a product of purine metabolism in most mammals except higher apes, and it is present in their urine. In humans, uric acid is excreted instead of allantoin. The presence of allantoin in the urine can be an indication of microbial overgrowth or it can be created via non-enzymatic means through high levels of reactive oxygen species. In this regard Allantoin is sometimes used as a marker of oxidative stress. Allantoin can be isolated from cow urine or as a botanical extract of the comfrey plant. It has long been used for its healing, soothing, and anti-irritating properties. Allantoin helps to heal wounds and skin irritations and stimulates the growth of healthy tissue. Allantoin can be found in anti-acne products, sun care products, and clarifying lotions because of its ability to help heal minor wounds and promote healthy skin. Allantoin is frequently present in toothpaste, mouthwash, and other oral hygiene products as well as shampoos, lipsticks, various cosmetic lotions and creams and other cosmetic and pharmaceutical products.
Allantoin is a metabolite found in or produced by Saccharomyces cerevisiae.
A urea hydantoin that is found in URINE and PLANTS and is used in dermatological preparations.
See also: Alcloxa (active moiety of); Comfrey Leaf (part of); Comfrey Root (part of) ... View More ...
Allantoin is a chemical compound with formula C4H6N4O3. It is also called 5-ureidohydantoin or glyoxyldiureide. It is a diureide of glyoxylic acid. Named after the allantois, an amniote embryonic excretory organ in which it concentrates during development in most mammals except humans and higher apes, it is a product of oxidation of uric acid by purine catabolism. After birth, it is the predominant means by which nitrogenous waste is excreted in the urine of these animals. In humans and higher apes, the metabolic pathway for conversion of uric acid to allantoin is not present, so the former is excreted. Recombinant rasburicase is sometimes used as a drug to catalyze this metabolic conversion in patients. In fish, allantoin is broken down further (into ammonia) before excretion. Allantoin is a major metabolic intermediate in many other organisms including plants and bacteria.; Its chemical formula is C4H6N4O3. It is also called 5-ureidohydantoin, glyoxyldiureide, and 5-ureidohydantoin. It is a product of oxidation of uric acid. It is a diureide of glyoxylic acid. It is a product of purine metabolism in most mammals except higher apes, and it is present in their urine. Allantoin is a botanical extract of the comfrey plant and is used for its healing, soothing, and anti-irritating properties. Allantoin helps to heal wounds and skin irritations and stimulate growth of healthy tissue. This extract can be found in anti-acne products, sun care products, and clarifying lotions because of its ability to help heal minor wounds and promote healthy skin.
Allantoin is a diureide of glyoxylic acid with the chemical formula C4H6N4O3. It is also called 5-ureidohydantoin or glyoxyldiureide. It is a product of the oxidation of uric acid. It is also a product of purine metabolism in most mammals except for higher apes, and it is present in their urine. In humans, uric acid is excreted instead of allantoin. The presence of allantoin in the urine can be an indication of microbial overgrowth or it can be created via non-enzymatic means through high levels of reactive oxygen species. In this regard, allantoin is sometimes used as a marker of oxidative stress. Allantoin can be isolated from cow urine or as a botanical extract of the comfrey plant. It has long been used for its healing, soothing, and anti-irritating properties. Allantoin helps to heal wounds and skin irritations and stimulates the growth of healthy tissue. Allantoin can be found in anti-acne products, sun care products, and clarifying lotions because of its ability to help heal minor wounds and promote healthy skin. Allantoin is frequently present in toothpaste, mouthwash, and other oral hygiene products as well as in shampoos, lipsticks, various cosmetic lotions and creams, and other cosmetic and pharmaceutical products. It is also a metabolite of Bacillus (PMID: 18302748) and Streptomyces (PMID: 24292080).
An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen.

Allantoin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=5377-33-3 (retrieved 2024-06-29) (CAS RN: 97-59-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth.
Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth.

同义名列表

308 个代谢物同义名

5-Ureidohydantoin; Glyoxyldiureide; Glyoxylic diureide; Cordianine; Glyoxyldiureid; (2,5-Dioxo-4-imidazolidinyl)urea; SECRETIPSS SCALP HAIR ESSENTIAL BOOSTERINTENSE CARE FOR DAMAGED SCALPS AND HAIRS; Allantoin, Pharmaceutical Secondary Standard; Certified Reference Material; Allantoin, United States Pharmacopeia (USP) Reference Standard; Allantoin, European Pharmacopoeia (EP) Reference Standard; NANOMIX NANO CLEANSkin Protectant Antibacterial Function; BOTANETH PRONOXIN HAIR REGAINER FS2 ACTIVATOR 2-A 2-B; SkinCeuticals Advanced Scar Control Skin Protectant; By Pharmicell Lab Luxury Cell Performance Emulsion; 3-Hydroxy-2-propyl-4-pentenoic Acid Ethyl Ester; By Pharmicell Lab Luxury Cell Performance Toner; Jabon Shelo Nabel Con Alantoina Baba de Caracol; By Pharmicell Lab Moisturizing Face Toning Mist; By Pharmicell Lab Luxury Cell Performance Serum; ORIGINAL POWER WHITENING AND LINELESS AMPOULE; Dr. Young 2P Pearl Brightening Balm SPF35 PA; 5-25-15-00338 (Beilstein Handbook Reference); Leaders Mediu Pore Cleaning Carbonated Pack; Shelo NABEL Baba de Caracol Locion Corporal; BIOXIDEA MIRACLE 48 EXCELLENCE DIAMOND MASK; HYUNDAE MEDITECH BIO HAIR SOLU TION ERUA DO; Vital Fluid II EGF and FGF Whitening Serum; SECRETIPSS SCALP HAIR ESSENTIAL TONIC PLUS; DGH Advanced Formula Scar Skin Protectant; Vital Fluid I Platinum Anti Wrinkle Serum; Urea, (2,5-dioxo-4-imidazolidinyl)- (9CI); Scar ReducerIntensive Herbal and Nutrient; QYO QYO Tangerine Bright Moist Mask Pack; BIOXIDEA MIRACLE 48 EXCELLENCE GOLD MASK; HAIRFILL SCALP HAIR ESSENTIAL TONIC PLUS; SECRETIPSS SCALP HAIR ESSENTIAL BOOSTER; BIOXIDEA ELEMENT 48 NATURA DIAMOND MASK; Sodium Methanethiolate (~20\\% in Water); By Pharmicell Lab The Prestige Essence; Cetaphil Baby Soothe and Protect Cream; N-(2,5-Dioxo-4(1h)-imidazolidinyl)urea; HAIRFILL SCALP HAIR ESSENTIAL BOOSTER; LEADERS MEDIU CALMING PEPPERMINT PACK; urea, N-(2,5-dioxo-4-imidazolidinyl)-; Skin Barista Rice Bran Cleansing Foam; NOBLESSE MANZ GROOMING SO CLEAN CARE; N-(2,5-Dioxo-4-imidazolidinyl)urea #; Lycoris rubus whitening moisturizing; BIOXIDEA ELEMENT 48 NATURA GOLD MASK; Reed and carnrick brand OF allantoin; IASOBETIC Allantoin Skin Protectant; Blister Armour Anti-FrictionMission; Urea, (2,5-dioxo-4-imidazolidinyl)-; M-Rose Seaweed Lifting Revitalizing; N-(2,5-Dioxo-4-imidazolidinyl)urea; Fikia Marine Delight Soothing Mist; Cellapy MGF Hydro Gel Intense Mask; Dr Deep Brightening FacialEmulsion; IONTOPHORESISANTI AGING SOLUTION I; U-max Whitening Functional Essence; N-(2,5-dioxoimidazolidin-4-yl)urea; 1-(2,5-dioxoimidazolidin-4-yl)urea; Ramosu The Witches Cream Pack Gold; 5-Ureidohydantoin;Glyoxyldiureide; Shelo NABEL Crema Baba de Caracol; Leaders Mediu Purifying Salt Pack; 2,5-Imidazolidinedione, 4-ureido-; component of Skin-balm (Salt/Mix); Dr Young 2p Blemish Base SPF35 PA; (2,5-Dioxo-4-imidazolidinyl)urea; Luxury Cell Performance Emulsion; Inflammation OTCRadiation Relief; Parma Anus Skin Premium Cleanser; Hasol Revitalizing Scalp Ampoule; (2,5-dioxoimidazolidin-4-yl)urea; Shelo NABEL CACAO Skin Protectan; Urea,5-dioxo-4-imidazolidinyl)-; Diabetic Wound Gel Professional; 4-ureido-2,5-Imidazolidinedione; 2,5-Dioxo-4-imidazolidinyl-urea; Cellpium vampire cleansing mask; Queen Perfume Hair Conditioner; Dermaheal Ultimatum PTx Sports; Allantoin, analytical standard; BK Cell 2STEP AQUA TOKTOK MASK; Macoma Senior Premium Cleanser; 5-Ureido-2,4-imidazolidindione; REBORNCELL AQUA RICH PURE SKIN; Vital Fluid IV Nano Gold Serum; Allantoin, p.a., 98.5-101.0\\%; Lycoris RUBUS Whitening Fluid; Luxury Cell Performance Toner; Luxury Cell Performance Serum; 5-Ureido-2,4-imidazolidindion; CVS Health Advanced Scar Gel; Well and Good Liquid Bandage; Allantoin (USAN:USP:BAN:JAN); Tamnamo Vital Hair Treatment; M-Rose Seaweed Essence Serum; PHYTON THERAPY CLEANSING BAR; M-Rose Seaweed Hydrogel Mask; VetraCare Pet Liquid Bandage; Allantoin [USAN:USP:BAN:JAN]; LUMINANT UMBRELLA MASK PACK; Shelo NABEL Baba de Caracol; Walgreens Advanced Scar Gel; 3CE FIXER AND MASCARA BLACK; Cetaphil Soothing Gel Cream; 3CE FIXER AND MASCARA BROWN; Campbell brand OF allantoin; Sheffield Advanced Scar Gel; Pelo Baum Hair Revitalizing; Dr. Dog Skin Care for Dogs; Calm and Heal Melting Balm; PLAGENTRA BABY BUBBLE WASH; OZ TREEHandMade by Dorothy; Rite Aid Advanced Scar Gel; Shelo NABEL Jabon Baba Car; Anti-Chafe StickPro Series; GMDANSU Herbal Mask Sheet; VET WORTHY LIQUID BANDAGE; ATOBOS BABY AQUA SOOTHING; Idelalisib metabolite m1a; ALLANTOIN (USP MONOGRAPH); REBORNCELL AQUA RICH SOFT; Baby Wipes with Allantoin; Bodyglide anti chafe balm; ALLANTOIN [USP MONOGRAPH]; DL-ALLANTOIN-5-13C; 1-15N; HAIRJOY MSM SCALP ESSENCE; ALLANTOIN (EP MONOGRAPH); Glyoxylic(acid) diureide; Sween brand OF allantoin; Miracle GYN (10 Tablets); Allantoin campbell brand; ALLANTOIN [EP MONOGRAPH]; Scar GelAdvanced Formula; Gene 16 Whitening Factor; Target Advanced Scar Gel; Secret Gyno (10 Tablets); Drs. pharmacy Scar Cream; Jilgyungyi (10 Tablets); Nano Gold Bio Mask Pack; Lycoris rubus whitening; Miracle GYN (2 Tablets); Miracle GYN (4 Tablets); Shelo NABEL D B T Cream; Allantoin, >=98.0\\% (N); Wound Gel Professional; First honey Burn Salve; SISEUNDEUSI BLESS BODY; NoblRose Foam Cleanser; Jilgyungyi (6 Tablets); Advanced Derma Therapy; SBS 41 Medicated Cream; BIOWHITE BEAUTY SERUM; Version X Scalp Tonic; Allantoin sween brand; Mederma Advanced Scar; REBORNCELL CLEANSING; Smart Brushing Tooth; Seaweed Aqua Massage; PORE CARE Lotus Mask; Ultra Soothing Toner; DR DEEP AQUA WRINKLE; Sarene Soothing Skin; Advanced Derma Spray; REVAGAIN Scalp Tonic; NEWSTEM Rx Intensive; Hydantoin, 5-ureido-; Allantoin [USAN:BAN]; The Prestige Essence; AVC/Dienestrolcream; Mandelic 2 Peel Gel; Pelo Baum Lash Lash; Allantoin (JAN/USP); Run Guard Sensitive; ARC Skin Protectant; FUCOIDAN HAIR TONIC; Kenaf wet wipe kids; BLACK CAVIDIOL MASK; Healing Head to Toe; Pelo Baum Brow Brow; Diabetic Wound Gel; Equate ScarTopical; Run Guard Original; 5-ureido-Hydantoin; Glyoxylic diureide; ALLANTOIN (USP-RS); ALLANTOIN [USP-RS]; 5-Ureidohydrantoin; ALLANTOIN [WHO-DD]; Mulberry Emulsion; ALLANTOIN [VANDF]; 5-Ureidohydantoin; ALLANTOIN (MART.); Bodyglide For Her; Prestwick1_000002; Prestwick3_000002; ALLANTOIN [MART.]; FUCOIDAN SKINCURE; Advanced Scar Gel; GMDANSU Eye Serum; Cutemol emollient; Prestwick0_000002; 97-59-6 (racemic); Prestwick2_000002; Spectrum2_000219; Spectrum4_000716; ALLANTOIN [HSDB]; AC Control Serum; ALLANTOIN [USAN]; BL Vital Essence; ALLANTOIN [INCI]; Vitamin C Liquid; Spectrum5_001526; Mederma for Kids; Spectrum3_000876; FUCOIDAN ESSENCE; Allantoin 0.5\\%; (+/-)-Allantoin; RAPHAGENPOWDE R; Meijer Scar Gel; ALLANTOIN [JAN]; Anti Chafe Balm; Allantoin Cream; Allantoin (8CI); Glyoxyldiureide; Burn-B Gone OTC; Allantoin-0.5\\%; DOG MX BANDAGE; ALLANTOIN [II]; Glyoxyldiureid; SOOSUL ESSENCE; Kenaf wet wipe; BL Vital Serum; ALLANTOIN (II); Mulberry Serum; Mulberry Toner; ALLANTOIN [MI]; U-max Multi BB; Allantoin .4\\%; Tox21_110395_1; DivK1c_000281; BL Vital Skin; BPBio1_000005; Chamois Glide; Sol Mouthwash; Oprea1_621175; Rite Aid Scar; (S)-Allantoin; KBio1_000281; Scar Reducer; KBio2_001558; NCI60_041675; DL-Allantoin; KBio2_006694; Tox21_302912; Tox21_202087; Tox21_110395; Allation,(S); KBio3_002051; Prestwick_11; KBio2_004126; GMDANSU Skin; ALRA THERAPY; MIRACLE GYN; Fancol TOIN; ATOBOS WASH; Equate Scar; Polyactil N; CAS-97-59-6; IDI1_000281; Herpecin L; Scar Cream; Cool Melon; Cordianine; ScarEquate; Herpecin-L; HealingCVS; ECO FACE 9; ALLOXANTIN; Bruise MD; AI3-15281; HerpecinL; Alantoina; Allantoin; Scar Care; Uniderm A; Teevodar; Psoralon; C4H6N4O3; Scar Gel; Alwextin; Woundres; DCH Scar; Scarderm; BL Vital; HAHALADY; Septalan; Allantol; Alantan; ScarCVS; Sebical; QC Scar; VASHTI; D00121; OHL O2; ATOBOS; Purple; NAAMAN; SEUK; Allantoin



数据库引用编号

29 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

321 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(315)

INOH(0)

PlantCyc(2)

COVID-19 Disease Map(0)

PathBank(4)

PharmGKB(0)

258 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Aigerim Soltabayeva, Assylay Kurmanbayeva, Aizat Bekturova, Dinara Oshanova, Zhadyrassyn Nurbekova, Sudhakar Srivastava, Dominic Standing, Edyta Zdunek-Zastocka, Moshe Sagi. Endogenous ureides are employed as a carbon source in Arabidopsis plants exposed to carbon starvation conditions. Plant science : an international journal of experimental plant biology. 2024 Jul; 344(?):112108. doi: 10.1016/j.plantsci.2024.112108. [PMID: 38705480]
  • Sorin Marian Mârza, Adela Maria Dăescu, Robert Cristian Purdoiu, Mădălina Dragomir, Mariana Tătaru, Iulia Melega, Andras-Laszlo Nagy, Adrian Gal, Flaviu Tăbăran, Sidonia Bogdan, Mirela Moldovan, Emoke Pall, Camelia Munteanu, Klara Magyari, Ionel Papuc. Healing of Skin Wounds in Rats Using Creams Based on Symphytum Officinale Extract. International journal of molecular sciences. 2024 Mar; 25(6):. doi: 10.3390/ijms25063099. [PMID: 38542069]
  • Xiaodan Meng, Zhiyong Zhang, Huali Wang, Furong Nai, Yihao Wei, Yongchun Li, Xinming Ma, Xiaochun Wang, Mechthild Tegeder. Multi-scale analysis provides insights into the roles of ureide permeases in wheat nitrogen use efficiency. Journal of experimental botany. 2023 Jul; ?(?):. doi: 10.1093/jxb/erad286. [PMID: 37478311]
  • Rizwan Alam, Rizwan Rasheed, Muhammad Arslan Ashraf, Iqbal Hussain, Shafaqat Ali. Allantoin alleviates chromium phytotoxic effects on wheat by regulating osmolyte accumulation, secondary metabolism, ROS homeostasis and nutrient acquisition. Journal of hazardous materials. 2023 Jun; 458(?):131920. doi: 10.1016/j.jhazmat.2023.131920. [PMID: 37413799]
  • Soni Chowrasia, Jyoti Nishad, Rekha Mahato, Kanti Kiran, Nitasana Rajkumari, Alok Kumar Panda, Hukam C Rawal, Mandira Barman, Tapan Kumar Mondal. Allantoin improves salinity tolerance in Arabidopsis and rice through synergid activation of abscisic acid and brassinosteroid biosynthesis. Plant molecular biology. 2023 May; ?(?):. doi: 10.1007/s11103-023-01350-8. [PMID: 37184674]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Sławomir Dresler, Maciej Strzemski, Izabela Baczewska, Mateusz Koselski, Mohammad Bagher Hassanpouraghdam, Dariusz Szczepanek, Ireneusz Sowa, Magdalena Wójciak, Agnieszka Hanaka. Extraction of Isoflavones, Alpha-Hydroxy Acids, and Allantoin from Soybean Leaves-Optimization by a Mixture Design of the Experimental Method. Molecules (Basel, Switzerland). 2023 May; 28(9):. doi: 10.3390/molecules28093963. [PMID: 37175385]
  • Sławomir Dresler, Robert Zubel, Izabela Baczewska, Michał Karakuła, Jan Sawicki, Agnieszka Hanaka, Sylwia Zielińska, Bartosz J Płachno, Ireneusz Sowa, Magdalena Wójciak, Maciej Strzemski. Is there any direct link between hazardous trace metals and the allantoin content in some moss species?. The Science of the total environment. 2023 Mar; 864(?):160653. doi: 10.1016/j.scitotenv.2022.160653. [PMID: 36529391]
  • Gang Wang, Jiali Li, Jing Ji, Lishuang Zhang, Bowen Li, Jiaqi Zhang, Xinya Wang, Wenju Song, Chunfeng Guan. Combined application of allantoin and strain JIT1 synergistically or additively promotes the growth of rice under 2, 4-DCP stress by enhancing the phosphate solubility, improving soil enzyme activities and photosynthesis. Journal of plant physiology. 2023 Jan; 282(?):153941. doi: 10.1016/j.jplph.2023.153941. [PMID: 36739690]
  • Shuai Lu, Zichang Jia, Xiangfeng Meng, Yaoyu Chen, Surong Wang, Chaozhen Fu, Lei Yang, Rong Zhou, Baohua Wang, Yunying Cao. Combined Metabolomic and Transcriptomic Analysis Reveals Allantoin Enhances Drought Tolerance in Rice. International journal of molecular sciences. 2022 Nov; 23(22):. doi: 10.3390/ijms232214172. [PMID: 36430648]
  • Joanda P R E Silva, Laiane C O Pereira, Lucas S Abreu, Francisca S V Lins, Thalisson A de Souza, Renan F do Espírito-Santo, Renata P C Barros, Cristiane F Villarreal, José I M de Melo, Marcus T Scotti, Vicente C de O Costa, Lucas H Martorano, Fernando M Dos Santos, Raimundo Braz Filho, Marcelo S da Silva, Josean F Tavares. Targeted Isolation of Anti-inflammatory Lignans from Justicia aequilabris by Molecular Networking Approach. Journal of natural products. 2022 09; 85(9):2184-2191. doi: 10.1021/acs.jnatprod.2c00478. [PMID: 35998343]
  • Fengjuan Zhang, Xinxiao Sun, Xiaolin Shen, Yajun Yan, Jia Wang, Qipeng Yuan. Biosynthesis of allantoin in Escherichia coli via screening a highly effective urate oxidase. Biotechnology and bioengineering. 2022 09; 119(9):2518-2528. doi: 10.1002/bit.28126. [PMID: 35488433]
  • Agnieszka Hanaka, Artur Nowak, Ewa Ozimek, Sławomir Dresler, Andrzej Plak, Agnieszka Sujak, Emilia Reszczyńska, Maciej Strzemski. Effect of copper stress on Phaseolus coccineus in the presence of exogenous methyl jasmonate and/or Serratia plymuthica from the Spitsbergen soil. Journal of hazardous materials. 2022 08; 436(?):129232. doi: 10.1016/j.jhazmat.2022.129232. [PMID: 35739752]
  • Sławomir Dresler, Jozef Kováčik, Ireneusz Sowa, Magdalena Wójciak, Maciej Strzemski, Anna Rysiak, Peter Babula, Christopher D Todd. Allantoin overaccumulation enhances production of metabolites under excess of metals but is not tightly regulated by nitric oxide. Journal of hazardous materials. 2022 08; 436(?):129138. doi: 10.1016/j.jhazmat.2022.129138. [PMID: 35617731]
  • Asmin Andries, Alan Feyaerts, Djalila Mekahli, Ann Van Schepdael. Quantification of allantoin and other metabolites of the purine degradation pathway in human plasma samples using a newly developed HILIC-LC-MS/MS method. Electrophoresis. 2022 05; 43(9-10):1010-1018. doi: 10.1002/elps.202100265. [PMID: 35050532]
  • Charussri Leeyaphan, Supenya Varothai, Suphattra Trakanwittayarak, Pranittra Suphatsathienkul, Suthasinee Pattaravadee, Lalita Matthapan, Waranyoo Prasong, Kamonpan Lertrujiwanit, Salisa Supcharoenkul, Kanokvalai Kulthanan. A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo. Journal of cosmetic dermatology. 2022 Feb; 21(2):679-688. doi: 10.1111/jocd.14125. [PMID: 33811776]
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