Allantoin (BioDeep_00000400042)

Main id: BioDeep_00000000111

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


(2,5-dioxoimidazolidin-4-yl)urea

化学式: C4H6N4O3 (158.044)
中文名称: 尿囊素
谱图信息: 最多检出来源 Homo sapiens(blood) 33.1%

分子结构信息

SMILES: C1(C(=NC(=N1)O)O)NC(=N)O
InChI: InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)

描述信息

C78284 - Agent Affecting Integumentary System > C29708 - Anti-psoriatic Agent
C78284 - Agent Affecting Integumentary System > C29700 - Astringent
D003879 - Dermatologic Agents
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; POJWUDADGALRAB-UHFFFAOYSA-N_STSL_0150_Allantoin_8000fmol_180425_S2_LC02_MS02_50; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth.
Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth.

同义名列表

5 个代谢物同义名

Allantoin; (2,5-dioxoimidazolidin-4-yl)urea; 5-Ureidohydantoin; Allantoin; Allantoin



数据库引用编号

63 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

256 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADA, ALB, ARG1, BCL2, CAT, GLUL, GLYCTK, NLRP3, XDH
Peripheral membrane protein 2 ADA, HSD17B6
Endoplasmic reticulum membrane 1 BCL2
Nucleus 6 ALB, ARG1, BCL2, GLUL, MPO, NLRP3
cytosol 11 ADA, ALB, ARG1, BCL2, CAT, GDA, GLUL, GLYCTK, GPT, NLRP3, XDH
centrosome 1 ALB
nucleoplasm 1 MPO
Cell membrane 3 ADA, GLUL, TNF
Lipid-anchor 1 GLUL
Cytoplasmic granule 1 ARG1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 2 GDA, SLC22A12
Golgi apparatus membrane 1 NLRP3
cell junction 1 ADA
cell surface 2 ADA, TNF
Golgi apparatus 2 ALB, GLYCTK
Golgi membrane 2 INS, NLRP3
mitochondrial inner membrane 1 GDA
neuronal cell body 1 TNF
Cytoplasm, cytosol 2 GLUL, NLRP3
Lysosome 2 ADA, MPO
plasma membrane 4 ADA, GLUL, SLC22A12, TNF
Membrane 5 ADA, BCL2, CAT, NLRP3, SLC22A12
apical plasma membrane 1 SLC22A12
extracellular exosome 7 ALB, CAT, GLUL, GPT, LYZ, MPO, SLC22A12
Lumenal side 1 HSD17B6
endoplasmic reticulum 5 ALB, BCL2, GLUL, HSD17B6, NLRP3
extracellular space 9 ALB, ARG1, CCL2, CXCL8, INS, LYZ, MPO, TNF, XDH
mitochondrion 6 BCL2, CAT, GDA, GLUL, GLYCTK, NLRP3
protein-containing complex 3 ALB, BCL2, CAT
intracellular membrane-bounded organelle 3 CAT, HSD17B6, MPO
Microsome membrane 1 HSD17B6
Secreted 5 ALB, CCL2, CXCL8, INS, NLRP3
extracellular region 10 ALB, ARG1, CAT, CCL2, CXCL8, INS, LYZ, MPO, NLRP3, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 1 CAT
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 2 ADA, ALB
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 ADA, TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 SLC22A12
Mitochondrion inner membrane 1 GDA
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 CAT
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 MPO
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
ciliary basal body 1 ALB
phagocytic cup 1 TNF
centriole 1 ALB
brush border membrane 1 SLC22A12
spindle pole 1 ALB
blood microparticle 1 ALB
Endomembrane system 1 NLRP3
endosome lumen 1 INS
microtubule organizing center 1 NLRP3
cell body 1 GLUL
myelin sheath 1 BCL2
azurophil granule 1 MPO
[Isoform 1]: Cytoplasm 1 GLYCTK
Microsome 1 GLUL
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 ALB, INS
platelet alpha granule lumen 1 ALB
specific granule lumen 2 ARG1, LYZ
tertiary granule lumen 1 LYZ
transport vesicle 1 INS
azurophil granule lumen 3 ARG1, LYZ, MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
phagocytic vesicle lumen 1 MPO
glial cell projection 1 GLUL
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
BAD-BCL-2 complex 1 BCL2
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Aigerim Soltabayeva, Assylay Kurmanbayeva, Aizat Bekturova, Dinara Oshanova, Zhadyrassyn Nurbekova, Sudhakar Srivastava, Dominic Standing, Edyta Zdunek-Zastocka, Moshe Sagi. Endogenous ureides are employed as a carbon source in Arabidopsis plants exposed to carbon starvation conditions. Plant science : an international journal of experimental plant biology. 2024 Jul; 344(?):112108. doi: 10.1016/j.plantsci.2024.112108. [PMID: 38705480]
  • Sorin Marian Mârza, Adela Maria Dăescu, Robert Cristian Purdoiu, Mădălina Dragomir, Mariana Tătaru, Iulia Melega, Andras-Laszlo Nagy, Adrian Gal, Flaviu Tăbăran, Sidonia Bogdan, Mirela Moldovan, Emoke Pall, Camelia Munteanu, Klara Magyari, Ionel Papuc. Healing of Skin Wounds in Rats Using Creams Based on Symphytum Officinale Extract. International journal of molecular sciences. 2024 Mar; 25(6):. doi: 10.3390/ijms25063099. [PMID: 38542069]
  • Xiaodan Meng, Zhiyong Zhang, Huali Wang, Furong Nai, Yihao Wei, Yongchun Li, Xinming Ma, Xiaochun Wang, Mechthild Tegeder. Multi-scale analysis provides insights into the roles of ureide permeases in wheat nitrogen use efficiency. Journal of experimental botany. 2023 Jul; ?(?):. doi: 10.1093/jxb/erad286. [PMID: 37478311]
  • Rizwan Alam, Rizwan Rasheed, Muhammad Arslan Ashraf, Iqbal Hussain, Shafaqat Ali. Allantoin alleviates chromium phytotoxic effects on wheat by regulating osmolyte accumulation, secondary metabolism, ROS homeostasis and nutrient acquisition. Journal of hazardous materials. 2023 Jun; 458(?):131920. doi: 10.1016/j.jhazmat.2023.131920. [PMID: 37413799]
  • Soni Chowrasia, Jyoti Nishad, Rekha Mahato, Kanti Kiran, Nitasana Rajkumari, Alok Kumar Panda, Hukam C Rawal, Mandira Barman, Tapan Kumar Mondal. Allantoin improves salinity tolerance in Arabidopsis and rice through synergid activation of abscisic acid and brassinosteroid biosynthesis. Plant molecular biology. 2023 May; ?(?):. doi: 10.1007/s11103-023-01350-8. [PMID: 37184674]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Sławomir Dresler, Maciej Strzemski, Izabela Baczewska, Mateusz Koselski, Mohammad Bagher Hassanpouraghdam, Dariusz Szczepanek, Ireneusz Sowa, Magdalena Wójciak, Agnieszka Hanaka. Extraction of Isoflavones, Alpha-Hydroxy Acids, and Allantoin from Soybean Leaves-Optimization by a Mixture Design of the Experimental Method. Molecules (Basel, Switzerland). 2023 May; 28(9):. doi: 10.3390/molecules28093963. [PMID: 37175385]
  • Sławomir Dresler, Robert Zubel, Izabela Baczewska, Michał Karakuła, Jan Sawicki, Agnieszka Hanaka, Sylwia Zielińska, Bartosz J Płachno, Ireneusz Sowa, Magdalena Wójciak, Maciej Strzemski. Is there any direct link between hazardous trace metals and the allantoin content in some moss species?. The Science of the total environment. 2023 Mar; 864(?):160653. doi: 10.1016/j.scitotenv.2022.160653. [PMID: 36529391]
  • Gang Wang, Jiali Li, Jing Ji, Lishuang Zhang, Bowen Li, Jiaqi Zhang, Xinya Wang, Wenju Song, Chunfeng Guan. Combined application of allantoin and strain JIT1 synergistically or additively promotes the growth of rice under 2, 4-DCP stress by enhancing the phosphate solubility, improving soil enzyme activities and photosynthesis. Journal of plant physiology. 2023 Jan; 282(?):153941. doi: 10.1016/j.jplph.2023.153941. [PMID: 36739690]
  • Shuai Lu, Zichang Jia, Xiangfeng Meng, Yaoyu Chen, Surong Wang, Chaozhen Fu, Lei Yang, Rong Zhou, Baohua Wang, Yunying Cao. Combined Metabolomic and Transcriptomic Analysis Reveals Allantoin Enhances Drought Tolerance in Rice. International journal of molecular sciences. 2022 Nov; 23(22):. doi: 10.3390/ijms232214172. [PMID: 36430648]
  • Joanda P R E Silva, Laiane C O Pereira, Lucas S Abreu, Francisca S V Lins, Thalisson A de Souza, Renan F do Espírito-Santo, Renata P C Barros, Cristiane F Villarreal, José I M de Melo, Marcus T Scotti, Vicente C de O Costa, Lucas H Martorano, Fernando M Dos Santos, Raimundo Braz Filho, Marcelo S da Silva, Josean F Tavares. Targeted Isolation of Anti-inflammatory Lignans from Justicia aequilabris by Molecular Networking Approach. Journal of natural products. 2022 09; 85(9):2184-2191. doi: 10.1021/acs.jnatprod.2c00478. [PMID: 35998343]
  • Fengjuan Zhang, Xinxiao Sun, Xiaolin Shen, Yajun Yan, Jia Wang, Qipeng Yuan. Biosynthesis of allantoin in Escherichia coli via screening a highly effective urate oxidase. Biotechnology and bioengineering. 2022 09; 119(9):2518-2528. doi: 10.1002/bit.28126. [PMID: 35488433]
  • Agnieszka Hanaka, Artur Nowak, Ewa Ozimek, Sławomir Dresler, Andrzej Plak, Agnieszka Sujak, Emilia Reszczyńska, Maciej Strzemski. Effect of copper stress on Phaseolus coccineus in the presence of exogenous methyl jasmonate and/or Serratia plymuthica from the Spitsbergen soil. Journal of hazardous materials. 2022 08; 436(?):129232. doi: 10.1016/j.jhazmat.2022.129232. [PMID: 35739752]
  • Sławomir Dresler, Jozef Kováčik, Ireneusz Sowa, Magdalena Wójciak, Maciej Strzemski, Anna Rysiak, Peter Babula, Christopher D Todd. Allantoin overaccumulation enhances production of metabolites under excess of metals but is not tightly regulated by nitric oxide. Journal of hazardous materials. 2022 08; 436(?):129138. doi: 10.1016/j.jhazmat.2022.129138. [PMID: 35617731]
  • Asmin Andries, Alan Feyaerts, Djalila Mekahli, Ann Van Schepdael. Quantification of allantoin and other metabolites of the purine degradation pathway in human plasma samples using a newly developed HILIC-LC-MS/MS method. Electrophoresis. 2022 05; 43(9-10):1010-1018. doi: 10.1002/elps.202100265. [PMID: 35050532]
  • Charussri Leeyaphan, Supenya Varothai, Suphattra Trakanwittayarak, Pranittra Suphatsathienkul, Suthasinee Pattaravadee, Lalita Matthapan, Waranyoo Prasong, Kamonpan Lertrujiwanit, Salisa Supcharoenkul, Kanokvalai Kulthanan. A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo. Journal of cosmetic dermatology. 2022 Feb; 21(2):679-688. doi: 10.1111/jocd.14125. [PMID: 33811776]
  • Ming-Zhu Lu, Amanda M Carter, Mechthild Tegeder. Altering ureide transport in nodulated soybean results in whole-plant adjustments of metabolism, assimilate partitioning, and sink strength. Journal of plant physiology. 2022 Feb; 269(?):153613. doi: 10.1016/j.jplph.2021.153613. [PMID: 35033961]
  • Dmitri Svistounov, Marit D Solbu, Trond G Jenssen, Ulla Dorte Mathisen, Terkel Hansen, Katja Benedikte Prestø Elgstøen, Svetlana N Zykova. Development of quantitative assay for simultaneous measurement of purine metabolites and creatinine in biobanked urine by liquid chromatography-tandem mass spectrometry. Scandinavian journal of clinical and laboratory investigation. 2022 02; 82(1):37-49. doi: 10.1080/00365513.2021.2015799. [PMID: 35048747]
  • Aigerim Soltabayeva, Aizat Bekturova, Assylay Kurmanbayeva, Dinara Oshanova, Zhadyrassyn Nurbekova, Sudhakar Srivastava, Dominic Standing, Moshe Sagi. Ureides are accumulated similarly in response to UV-C irradiation and wounding in Arabidopsis leaves but are remobilized differently during recovery. Journal of experimental botany. 2022 01; 73(3):1016-1032. doi: 10.1093/jxb/erab441. [PMID: 34606608]
  • Lenka Hasíková, Jakub Závada, Tereza Serranová, Lenka Kotačková, Petr Kozlík, Květa Kalíková, Jiří Trnka, David Zogala, Karel Šonka, Evžen Růžička, Petr Dušek. Patients with REM sleep behavior disorder have higher serum levels of allantoin. Parkinsonism & related disorders. 2021 09; 90(?):38-43. doi: 10.1016/j.parkreldis.2021.07.031. [PMID: 34352609]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Yuki Ono, Masashige Fukasawa, Kuni Sueyoshi, Norikuni Ohtake, Takashi Sato, Sayuri Tanabata, Ryo Toyota, Kyoko Higuchi, Akihiro Saito, Takuji Ohyama. Application of Nitrate, Ammonium, or Urea Changes the Concentrations of Ureides, Urea, Amino Acids and Other Metabolites in Xylem Sap and in the Organs of Soybean Plants (Glycine max (L.) Merr.). International journal of molecular sciences. 2021 Apr; 22(9):. doi: 10.3390/ijms22094573. [PMID: 33925462]
  • Yan-Ge Yu, Xiao-Yang Guo, Xiang-Yang Li, Dan-Dan Dai, Xin-Ran Xu, Xiao-Jin Ge, Yan-Jun Li, Tie-Gang Yang. Organ- and Age-Specific Differences of Dioscorea polystachya Compounds Measured by UPLC-QTOF/MS. Chemistry & biodiversity. 2021 Feb; 18(2):e2000856. doi: 10.1002/cbdv.202000856. [PMID: 33295037]
  • Anna Campanati, Gabriele Ceccarelli, Valerio Brisigotti, Elisa Molinelli, Emanuela Martina, Davide Talevi, Barbara Marconi, Melania Giannoni, Vasiliki Markantoni, Stamatios Gregoriou, George Kontochristopoulos, Annamaria Offidani. Effects of in vivo application of an overnight patch containing Allium cepa, allantoin, and pentaglycan on hypertrophic scars and keloids: Clinical, videocapillaroscopic, and ultrasonographic study. Dermatologic therapy. 2021 01; 34(1):e14665. doi: 10.1111/dth.14665. [PMID: 33314582]
  • Ying-Ying Teng, Ming-Li Zou, Feng-Lai Yuan, Xiao-Jin Zhou. Letter to the Editor on Objective evaluation of an occlusive overnight intensive patch containing onion extract and allantoin for hypertrophic scars. Journal of cosmetic dermatology. 2020 Dec; 19(12):3428. doi: 10.1111/jocd.13671. [PMID: 32794306]
  • Shuo Liu, Xuemei Yuan, Chang Ma, Jing Zhao, Zhili Xiong. 1H-NMR-based urinary metabolomic analysis for the preventive effects of gushudan on glucocorticoid-induced osteoporosis rats. Analytical biochemistry. 2020 12; 610(?):113992. doi: 10.1016/j.ab.2020.113992. [PMID: 33075315]
  • Kivanc Seref, Kaan Sonmez, Merve Altin Gulburun, Ozgur Ekinci, Ceren Bilkan Oge, Ozlem Gulbahar, Burak Arslan, Hasan Dagli, Ramazan Karabulut, Zafer Turkyilmaz. Protective Effects of Contractubex® on Stricture Formation after Experimental Corrosive Esophageal Burns in Rats. Archives of medical research. 2020 10; 51(7):664-669. doi: 10.1016/j.arcmed.2020.06.017. [PMID: 32654881]
  • Ayane Moriyama, Masutoshi Nojiri, Go Watanabe, Shinichi Enoki, Shunji Suzuki. Exogenous allantoin improves anthocyanin accumulation in grape berry skin at early stage of ripening. Journal of plant physiology. 2020 Oct; 253(?):153253. doi: 10.1016/j.jplph.2020.153253. [PMID: 32828011]
  • Junnan Ma, Xianglong Meng, Yi Liu, Cheng Yin, Tong Zhang, Piao Wang, Yong-Ki Park, Hyo Won Jung. Effects of a rhizome aqueous extract of Dioscorea batatas and its bioactive compound, allantoin in high fat diet and streptozotocin-induced diabetic mice and the regulation of liver, pancreas and skeletal muscle dysfunction. Journal of ethnopharmacology. 2020 Sep; 259(?):112926. doi: 10.1016/j.jep.2020.112926. [PMID: 32380247]
  • Ignacio Lescano, Andrés Matías Devegili, Carolina Martini, Tomás María Tessi, Claudio Alejandro González, Marcelo Desimone. Ureide metabolism in Arabidopsis thaliana is modulated by C:N balance. Journal of plant research. 2020 Sep; 133(5):739-749. doi: 10.1007/s10265-020-01215-x. [PMID: 32740857]
  • Lei Liu, Dan Liu, Ziyang Wang, Chunlei Zou, Bin Wang, He Zhang, Zhijia Gai, Pengfei Zhang, Yubo Wang, Caifeng Li. Exogenous allantoin improves the salt tolerance of sugar beet by increasing putrescine metabolism and antioxidant activities. Plant physiology and biochemistry : PPB. 2020 Sep; 154(?):699-713. doi: 10.1016/j.plaphy.2020.06.034. [PMID: 32750647]
  • Anne Guertler, Hannah Schwaiger, Julian Poetschke, Stephanie Steckmeier, Gerd Gauglitz. Objective evaluation of an occlusive overnight intensive patch containing onion extract and allantoin for hypertrophic scars. Journal of cosmetic dermatology. 2020 Sep; 19(9):2415-2420. doi: 10.1111/jocd.13561. [PMID: 32573095]
  • Tao Chen, Wei Zhang, Gang Yang, Jia-Hui Chen, Bi-Xia Chen, Rui Sun, Hua Zhang, Li-Zhe An. TRANSTHYRETIN-LIKE and BYPASS1-LIKE co-regulate growth and cold tolerance in Arabidopsis. BMC plant biology. 2020 Jul; 20(1):332. doi: 10.1186/s12870-020-02534-w. [PMID: 32664862]
  • Laith Z Samarah, Tina H Tran, Gary Stacey, Akos Vertes. In Vivo Chemical Analysis of Plant Sap from the Xylem and Single Parenchymal Cells by Capillary Microsampling Electrospray Ionization Mass Spectrometry. Analytical chemistry. 2020 05; 92(10):7299-7306. doi: 10.1021/acs.analchem.0c00939. [PMID: 32343130]
  • Lei Liu, Bin Wang, Dan Liu, Chunlei Zou, Peiran Wu, Ziyang Wang, Yubo Wang, Caifeng Li. Transcriptomic and metabolomic analyses reveal mechanisms of adaptation to salinity in which carbon and nitrogen metabolism is altered in sugar beet roots. BMC plant biology. 2020 Apr; 20(1):138. doi: 10.1186/s12870-020-02349-9. [PMID: 32245415]
  • Katarzyna Kimel, Magdalena Zienkiewicz, Barbara Sparzak-Stefanowska, Mirosława Krauze-Baranowska. TLC-densitometric analysis of allantoin in Symphytum officinale L. roots. Acta pharmaceutica (Zagreb, Croatia). 2020 Mar; 70(1):101-110. doi: 10.2478/acph-2020-0014. [PMID: 31677368]
  • Ignacio Lescano, María Florencia Bogino, Carolina Martini, Tomás María Tessi, Claudio Alejandro González, Karin Schumacher, Marcelo Desimone. Ureide Permease 5 (AtUPS5) Connects Cell Compartments Involved in Ureide Metabolism. Plant physiology. 2020 03; 182(3):1310-1325. doi: 10.1104/pp.19.01136. [PMID: 31862838]
  • Petr Kozlik, Lenka Hasikova, Blanka Stiburkova, Jakub Zavada, Kveta Kalikova. Rapid and reliable HILIC-MS/MS method for monitoring allantoin as a biomarker of oxidative stress. Analytical biochemistry. 2020 01; 589(?):113509. doi: 10.1016/j.ab.2019.113509. [PMID: 31747555]
  • G V Gonchakov, Yu A Merkulova. [Evaluation of advantages of Contractubex gel usage for postsurgical scars treatment in comparison with absence of systematized topical scars treatment of kids with congenital cleft lip and palate]. Khirurgiia. 2020; ?(4):88-94. doi: 10.17116/hirurgia202004188. [PMID: 32352676]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Agnieszka Hanaka, Sławomir Dresler, Magdalena Wójciak-Kosior, Maciej Strzemski, Jozef Kováčik, Michał Latalski, Grażyna Zawiślak, Ireneusz Sowa. The Impact of Long-and Short-Term Strontium Treatment on Metabolites and Minerals in Glycine max. Molecules (Basel, Switzerland). 2019 Oct; 24(21):. doi: 10.3390/molecules24213825. [PMID: 31652846]
  • Lenka Hasikova, Marketa Pavlikova, Hana Hulejova, Petr Kozlik, Kveta Kalikova, Aparna Mahajan, Martin Herrmann, Blanka Stiburkova, Jakub Zavada. Serum uric acid increases in patients with systemic autoimmune rheumatic diseases after 3 months of treatment with TNF inhibitors. Rheumatology international. 2019 Oct; 39(10):1749-1757. doi: 10.1007/s00296-019-04394-6. [PMID: 31363829]
  • Mark Christian Felipe R Redillas, Seung Woon Bang, Dong-Keun Lee, Youn Shic Kim, Harin Jung, Pil Joong Chung, Joo-Won Suh, Ju-Kon Kim. Allantoin accumulation through overexpression of ureide permease1 improves rice growth under limited nitrogen conditions. Plant biotechnology journal. 2019 07; 17(7):1289-1301. doi: 10.1111/pbi.13054. [PMID: 30565833]
  • Shah Fahad, Faheem Ahmed Khan, NuruliarizkiShinta Pandupuspitasari, Saddam Hussain, Imtiaz Ali Khan, Muhammad Saeed, Shah Saud, Shah Hassan, Muhammad Adnan, Amanullah, Muhammad Arif, Mukhtar Alam, Hidayat Ullah, Khalid Rehman Hakeem, Hesham Alharby, Muhammad Riaz, Muhammad Sameeullah, Hafiz Mohkum Hammad, Wajid Nasim, Shakeel Ahmad, Muhammad Afzal, Salem Safer Alghamdi, Atif A Bamagoos, Elsayed Fathi Abd Allah, Jianliang Huang. Suppressing photorespiration for the improvement in photosynthesis and crop yields: A review on the role of S-allantoin as a nitrogen source. Journal of environmental management. 2019 May; 237(?):644-651. doi: 10.1016/j.jenvman.2019.02.082. [PMID: 30870683]
  • Agnieszka Hanaka, Artur Nowak, Andrzej Plak, Sławomir Dresler, Ewa Ozimek, Jolanta Jaroszuk-Ściseł, Magdalena Wójciak-Kosior, Ireneusz Sowa. Bacterial Isolate Inhabiting Spitsbergen Soil Modifies the Physiological Response of Phaseolus coccineus in Control Conditions and under Exogenous Application of Methyl Jasmonate and Copper Excess. International journal of molecular sciences. 2019 Apr; 20(8):. doi: 10.3390/ijms20081909. [PMID: 30999692]
  • Sławomir Dresler, Barbara Hawrylak-Nowak, Jozef Kováčik, Martyna Pochwatka, Agnieszka Hanaka, Maciej Strzemski, Ireneusz Sowa, Magdalena Wójciak-Kosior. Allantoin attenuates cadmium-induced toxicity in cucumber plants. Ecotoxicology and environmental safety. 2019 Apr; 170(?):120-126. doi: 10.1016/j.ecoenv.2018.11.119. [PMID: 30529610]
  • Alberto Casartelli, Vanessa J Melino, Ute Baumann, Matteo Riboni, Radoslaw Suchecki, Nirupama S Jayasinghe, Himasha Mendis, Mutsumi Watanabe, Alexander Erban, Ellen Zuther, Rainer Hoefgen, Ute Roessner, Mamoru Okamoto, Sigrid Heuer. Opposite fates of the purine metabolite allantoin under water and nitrogen limitations in bread wheat. Plant molecular biology. 2019 Mar; 99(4-5):477-497. doi: 10.1007/s11103-019-00831-z. [PMID: 30721380]
  • Maryam Nourimand, Christopher D Todd. There is a direct link between allantoin concentration and cadmium tolerance in Arabidopsis. Plant physiology and biochemistry : PPB. 2019 Feb; 135(?):441-449. doi: 10.1016/j.plaphy.2018.11.016. [PMID: 30473421]
  • Sławomir Dresler, Magdalena Wójciak-Kosior, Ireneusz Sowa, Maciej Strzemski, Jan Sawicki, Jozef Kováčik, Tomasz Blicharski. Effect of Long-Term Strontium Exposure on the Content of Phytoestrogens and Allantoin in Soybean. International journal of molecular sciences. 2018 Dec; 19(12):. doi: 10.3390/ijms19123864. [PMID: 30518039]
  • Hiroshi Takagi, Shunsuke Watanabe, Shoma Tanaka, Takakazu Matsuura, Izumi C Mori, Takashi Hirayama, Hiroshi Shimada, Atsushi Sakamoto. Disruption of ureide degradation affects plant growth and development during and after transition from vegetative to reproductive stages. BMC plant biology. 2018 Nov; 18(1):287. doi: 10.1186/s12870-018-1491-2. [PMID: 30458716]
  • Aigerim Soltabayeva, Sudhakar Srivastava, Assylay Kurmanbayeva, Aizat Bekturova, Robert Fluhr, Moshe Sagi. Early Senescence in Older Leaves of Low Nitrate-Grown Atxdh1 Uncovers a Role for Purine Catabolism in N Supply. Plant physiology. 2018 11; 178(3):1027-1044. doi: 10.1104/pp.18.00795. [PMID: 30190419]
  • Tesfahun Dessale Admasu, Krishna Chaithanya Batchu, Diogo Barardo, Li Fang Ng, Vanessa Yuk Man Lam, Linfan Xiao, Amaury Cazenave-Gassiot, Markus R Wenk, Nicholas S Tolwinski, Jan Gruber. Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling. Developmental cell. 2018 10; 47(1):67-79.e5. doi: 10.1016/j.devcel.2018.09.001. [PMID: 30269951]
  • Asmin Andries, Stéphanie De Rechter, Peter Janssens, Djalila Mekahli, Ann Van Schepdael. Simultaneous determination of allantoin and adenosine in human urine using liquid chromatography - UV detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2018 Oct; 1096(?):201-207. doi: 10.1016/j.jchromb.2018.08.026. [PMID: 30176509]
  • Ning Zhou, Meng-Nan Zeng, Kai Li, Yan-Yun Yang, Zhi-Yao Bai, Xiao-Ke Zheng, Wei-Sheng Feng. An integrated metabolomic strategy for the characterization of the effects of Chinese yam and its three active components on septic cardiomyopathy. Food & function. 2018 Sep; 9(9):4989-4997. doi: 10.1039/c8fo00688a. [PMID: 30187904]
  • Huseyin Bozkurt, Emel Cicek Bozkurt, Hulya Ozpinar, Densel Arac, Ismail Kaya, Hidir Ozer, Reyhan Egilmez. Comparison of the Effects of Contractubex Gel and Benzothiazole After Topical Application in an Experimental Model of Epidural Fibrosis in Rats. World neurosurgery. 2018 Sep; 117(?):e403-e410. doi: 10.1016/j.wneu.2018.06.044. [PMID: 29913295]
  • Junnan Ma, Seok Yong Kang, Xianglong Meng, An Na Kang, Jong Hun Park, Yong-Ki Park, Hyo Won Jung. Effects of Rhizome Extract of Dioscorea batatas and Its Active Compound, Allantoin, on the Regulation of Myoblast Differentiation and Mitochondrial Biogenesis in C2C12 Myotubes. Molecules (Basel, Switzerland). 2018 Aug; 23(8):. doi: 10.3390/molecules23082023. [PMID: 30104552]
  • Jiun-Ruey Hu, Josef Coresh, Lesley A Inker, Andrew S Levey, Zihe Zheng, Casey M Rebholz, Adrienne Tin, Lawrence J Appel, Jingsha Chen, Mark J Sarnak, Morgan E Grams. Serum metabolites are associated with all-cause mortality in chronic kidney disease. Kidney international. 2018 08; 94(2):381-389. doi: 10.1016/j.kint.2018.03.008. [PMID: 29871777]
  • Chih-Yung Chiu, Gigin Lin, Mei-Ling Cheng, Meng-Han Chiang, Ming-Han Tsai, Kuan-Wen Su, Man-Chin Hua, Sui-Ling Liao, Shen-Hao Lai, Tsung-Chieh Yao, Kuo-Wei Yeh, Jing-Long Huang. Longitudinal urinary metabolomic profiling reveals metabolites for asthma development in early childhood. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. 2018 08; 29(5):496-503. doi: 10.1111/pai.12909. [PMID: 29679407]
  • Young Hye Seo, Ju-Hyun Jeon, Miran Jeong, Seung Mok Ryu, Won Kyung Jeon, Dae Sik Jang, Sang Hee Shim, Dongho Lee, Jung-Hye Choi, Jun Lee. Chemical Constituents of Apios americana Tubers and Their Inhibitory Activities on Nitric Oxide Production in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. Journal of natural products. 2018 07; 81(7):1598-1603. doi: 10.1021/acs.jnatprod.8b00182. [PMID: 29932657]
  • Ana M Gil, Daniela Duarte, Joana Pinto, António S Barros. Assessing Exposome Effects on Pregnancy through Urine Metabolomics of a Portuguese (Estarreja) Cohort. Journal of proteome research. 2018 03; 17(3):1278-1289. doi: 10.1021/acs.jproteome.7b00878. [PMID: 29424227]
  • Ireneusz Sowa, Roman Paduch, Maciej Strzemski, Sylwia Zielińska, Ewelina Rydzik-Strzemska, Jan Sawicki, Ryszard Kocjan, Janusz Polkowski, Adam Matkowski, Michał Latalski, Magdalena Wójciak-Kosior. Proliferative and antioxidant activity of Symphytum officinale root extract. Natural product research. 2018 Mar; 32(5):605-609. doi: 10.1080/14786419.2017.1326492. [PMID: 28490191]
  • Tsutomu Arakawa, Nasib Karl Maluf. The effects of allantoin, arginine and NaCl on thermal melting and aggregation of ribonuclease, bovine serum albumin and lysozyme. International journal of biological macromolecules. 2018 Feb; 107(Pt B):1692-1696. doi: 10.1016/j.ijbiomac.2017.10.034. [PMID: 29017881]
  • Solmaz Irani, Christopher D Todd. Exogenous allantoin increases Arabidopsis seedlings tolerance to NaCl stress and regulates expression of oxidative stress response genes. Journal of plant physiology. 2018 Feb; 221(?):43-50. doi: 10.1016/j.jplph.2017.11.011. [PMID: 29245127]
  • Gregorio Peron, Davide Santarossa, Dario Voinovich, Stefano Dall'Acqua, Stefania Sut. Urine metabolomics shows an induction of fatty acids metabolism in healthy adult volunteers after supplementation with green coffee (Coffea robusta L.) bean extract. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2018 Jan; 38(?):74-83. doi: 10.1016/j.phymed.2017.11.002. [PMID: 29425657]
  • M S Santana, K P Nascimento, P A Lotufo, I M Benseãor, F C Meotti. Allantoin as an independent marker associated with carotid intima-media thickness in subclinical atherosclerosis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 2018; 51(8):e7543. doi: 10.1590/1414-431x20187543. [PMID: 29924138]
  • David Perrett. Of urines and purines - a life in separation science. Nucleosides, nucleotides & nucleic acids. 2018; 37(11):588-602. doi: 10.1080/15257770.2018.1537493. [PMID: 30588861]
  • S V Minaev, A A Ivchenko, I I Babich, I N Gerasimenko, A V Isaeva, G S Ivchenko, A V Kachanov, Yu N Bolotov. [A new approach in the compression therapy of postoperative scars]. Khirurgiia. 2018 ; ?(2):79-84. doi: 10.17116/hirurgia2018279-84. [PMID: 29460884]
  • T Mikami, M Sorimachi. Uric acid contributes greatly to hepatic antioxidant capacity besides protein. Physiological research. 2017 12; 66(6):1001-1007. doi: 10.33549/physiolres.933555. [PMID: 28937257]
  • Maryam Nourimand, Christopher D Todd. Allantoin contributes to the stress response in cadmium-treated Arabidopsis roots. Plant physiology and biochemistry : PPB. 2017 Oct; 119(?):103-109. doi: 10.1016/j.plaphy.2017.08.012. [PMID: 28858669]
  • A Zinellu, S Sotgia, E Sotgiu, S Assaretti, A Baralla, A A Mangoni, A E Satta, C Carru. Cholesterol lowering treatment restores blood global DNA methylation in chronic kidney disease (CKD) patients. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2017 Sep; 27(9):822-829. doi: 10.1016/j.numecd.2017.06.011. [PMID: 28755807]
  • Linda H Münger, Alessia Trimigno, Gianfranco Picone, Carola Freiburghaus, Grégory Pimentel, Kathryn J Burton, François P Pralong, Nathalie Vionnet, Francesco Capozzi, René Badertscher, Guy Vergères. Identification of Urinary Food Intake Biomarkers for Milk, Cheese, and Soy-Based Drink by Untargeted GC-MS and NMR in Healthy Humans. Journal of proteome research. 2017 09; 16(9):3321-3335. doi: 10.1021/acs.jproteome.7b00319. [PMID: 28753012]
  • Elizabeth Caussé, Pauline Fournier, Jérome Roncalli, Robert Salvayre, Michel Galinier. Serum allantoin and aminothiols as biomarkers of chronic heart failure. Acta cardiologica. 2017 Aug; 72(4):397-403. doi: 10.1080/00015385.2017.1335104. [PMID: 28705092]
  • Sofia Balaska, Vassilios Myrianthopoulos, Martha Tselika, Dimitris G Hatzinikolaou, Emmanuel Mikros, George Diallinas. NmeA, a novel efflux transporter specific for nucleobases and nucleosides, contributes to metal resistance in Aspergillus nidulans. Molecular microbiology. 2017 Aug; 105(3):426-439. doi: 10.1111/mmi.13708. [PMID: 28509393]
  • Xiaohua Li, Yunfeng Bai, Feng Feng, Zhujun Zhang. A rapid and high-throughput method for the determination of serum uric acid based on microarray technology and nanomaterial. Luminescence : the journal of biological and chemical luminescence. 2017 Aug; 32(5):730-734. doi: 10.1002/bio.3243. [PMID: 27862937]
  • Irwin K Cheah, Richard M Y Tang, Terry S Z Yew, Keith H C Lim, Barry Halliwell. Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation. Antioxidants & redox signaling. 2017 02; 26(5):193-206. doi: 10.1089/ars.2016.6778. [PMID: 27488221]
  • Muhammad Saqib, Baohua Lou, Mohamed Ibrahim Halawa, Shimeles Addisu Kitte, Zhongyuan Liu, Guobao Xu. Chemiluminescence of Lucigenin-Allantoin and Its Application for the Detection of Allantoin. Analytical chemistry. 2017 02; 89(3):1863-1869. doi: 10.1021/acs.analchem.6b04271. [PMID: 28208242]
  • Qing-Qing Fang, Chun-Ye Chen, Min-Xia Zhang, Chun-Lan Huang, Xiao-Wei Wang, Ji-Hua Xu, Li-Hong Wu, Li-Yun Zhang, Wei-Qiang Tan. The Effectiveness of Topical Anti-scarring Agents and a Novel Combined Process on Cutaneous Scar Management. Current pharmaceutical design. 2017; 23(15):2268-2275. doi: 10.2174/1381612822666161025144434. [PMID: 27784253]
  • Maryam Nourimand, Christopher D Todd. Allantoin Increases Cadmium Tolerance in Arabidopsis via Activation of Antioxidant Mechanisms. Plant & cell physiology. 2016 Dec; 57(12):2485-2496. doi: 10.1093/pcp/pcw162. [PMID: 27742885]
  • K Inazawa, S Yamaguchi, M Hosoyamada, T Fukuuchi, N H Tomioka, N Yamaoka, K Kaneko. Urinary excretion of uric acid, allantoin, and 8-OH-Deoxyguanosine in uricase-knockout mice. Nucleosides, nucleotides & nucleic acids. 2016 Dec; 35(10-12):559-565. doi: 10.1080/15257770.2016.1163376. [PMID: 27906613]
  • Lana Shabala, Jingyi Zhang, Igor Pottosin, Jayakumar Bose, Min Zhu, Anja Thoe Fuglsang, Ana Velarde-Buendia, Amandine Massart, Camilla Beate Hill, Ute Roessner, Antony Bacic, Honghong Wu, Elisa Azzarello, Camilla Pandolfi, Meixue Zhou, Charlotte Poschenrieder, Stefano Mancuso, Sergey Shabala. Cell-Type-Specific H+-ATPase Activity in Root Tissues Enables K+ Retention and Mediates Acclimation of Barley (Hordeum vulgare) to Salinity Stress. Plant physiology. 2016 12; 172(4):2445-2458. doi: 10.1104/pp.16.01347. [PMID: 27770060]
  • Tomoyuki Minami, Misue Anda, Hisayuki Mitsui, Masayuki Sugawara, Takakazu Kaneko, Shusei Sato, Seishi Ikeda, Takashi Okubo, Hirohito Tsurumaru, Kiwamu Minamisawa. Metagenomic Analysis Revealed Methylamine and Ureide Utilization of Soybean-Associated Methylobacterium. Microbes and environments. 2016 Sep; 31(3):268-78. doi: 10.1264/jsme2.me16035. [PMID: 27431374]
  • Angelo Zinellu, Salvatore Sotgia, Arduino A Mangoni, Elisabetta Sotgiu, Sara Ena, Andrea E Satta, Ciriaco Carru. Effect of cholesterol lowering treatment on plasma markers of endothelial dysfunction in chronic kidney disease. Journal of pharmaceutical and biomedical analysis. 2016 Sep; 129(?):383-388. doi: 10.1016/j.jpba.2016.07.025. [PMID: 27454090]
  • Solmaz Irani, Christopher D Todd. Ureide metabolism under abiotic stress in Arabidopsis thaliana. Journal of plant physiology. 2016 Jul; 199(?):87-95. doi: 10.1016/j.jplph.2016.05.011. [PMID: 27302009]
  • Carlos Ignacio Lescano, Carolina Martini, Claudio Alejandro González, Marcelo Desimone. Allantoin accumulation mediated by allantoinase downregulation and transport by Ureide Permease 5 confers salt stress tolerance to Arabidopsis plants. Plant molecular biology. 2016 Jul; 91(4-5):581-95. doi: 10.1007/s11103-016-0490-7. [PMID: 27209043]
  • Iziara F Florentino, Daiany P B Silva, Pablinny M Galdino, Roberta C Lino, José L R Martins, Dayane M Silva, José R de Paula, Leonice M F Tresvenzol, Elson A Costa. Antinociceptive and anti-inflammatory effects of Memora nodosa and allantoin in mice. Journal of ethnopharmacology. 2016 Jun; 186(?):298-304. doi: 10.1016/j.jep.2016.04.010. [PMID: 27079223]
  • Yuanxue Liu, Hongfa Li, Yaya Fan, Shuli Man, Zhen Liu, Wenyuan Gao, Tingting Wang. Antioxidant and Antitumor Activities of the Extracts from Chinese Yam (Dioscorea opposite Thunb.) Flesh and Peel and the Effective Compounds. Journal of food science. 2016 Jun; 81(6):H1553-64. doi: 10.1111/1750-3841.13322. [PMID: 27122252]
  • Maria Letizia Manca, Pietro Matricardi, Claudia Cencetti, Josè Esteban Peris, Virginia Melis, Claudia Carbone, Elvira Escribano, Marco Zaru, Anna Maria Fadda, Maria Manconi. Combination of argan oil and phospholipids for the development of an effective liposome-like formulation able to improve skin hydration and allantoin dermal delivery. International journal of pharmaceutics. 2016 May; 505(1-2):204-11. doi: 10.1016/j.ijpharm.2016.04.008. [PMID: 27063848]
  • Bikash Baral, Jaime A Teixeira da Silva, Maria Luisa Izaguirre-Mayoral. Early signaling, synthesis, transport and metabolism of ureides. Journal of plant physiology. 2016 Apr; 193(?):97-109. doi: 10.1016/j.jplph.2016.01.013. [PMID: 26967003]
  • Ijeoma Esiaba, Danilyn M Angeles, Megan S Holden, John B C Tan, Yayesh Asmerom, Gerald Gollin, Danilo S Boskovic. Urinary Allantoin Is Elevated in Severe Intraventricular Hemorrhage in the Preterm Newborn. Translational stroke research. 2016 Apr; 7(2):97-102. doi: 10.1007/s12975-015-0405-y. [PMID: 25994284]
  • Hiroshi Takagi, Yasuhiro Ishiga, Shunsuke Watanabe, Tomokazu Konishi, Mayumi Egusa, Nobuhiro Akiyoshi, Takakazu Matsuura, Izumi C Mori, Takashi Hirayama, Hironori Kaminaka, Hiroshi Shimada, Atsushi Sakamoto. Allantoin, a stress-related purine metabolite, can activate jasmonate signaling in a MYC2-regulated and abscisic acid-dependent manner. Journal of experimental botany. 2016 Apr; 67(8):2519-2532. doi: 10.1093/jxb/erw071. [PMID: 26931169]
  • Radhika Sampat, Sarah Young, Ami Rosen, Douglas Bernhard, David Millington, Stewart Factor, H A Jinnah. Potential mechanisms for low uric acid in Parkinson disease. Journal of neural transmission (Vienna, Austria : 1996). 2016 Apr; 123(4):365-70. doi: 10.1007/s00702-015-1503-4. [PMID: 26747026]
  • Stefano Dall'Acqua, Matteo Stocchero, Irene Boschiero, Mariano Schiavon, Samuel Golob, Jalal Uddin, Dario Voinovich, Stefano Mammi, Elisabetta Schievano. New findings on the in vivo antioxidant activity of Curcuma longa extract by an integrated (1)H NMR and HPLC-MS metabolomic approach. Fitoterapia. 2016 Mar; 109(?):125-31. doi: 10.1016/j.fitote.2015.12.013. [PMID: 26712080]
  • Oguz Elmas, Onur Elmas, Yakup Aliciguzel, Tayyup Simsek. The relationship between hypertension and plasma allantoin, uric acid, xanthine oxidase activity and nitrite, and their predictive capacity in severe preeclampsia. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. 2016; 36(1):34-8. doi: 10.3109/01443615.2015.1030608. [PMID: 26366935]
  • Kristina Meichner, Sandra A Olsson, Danielle R Stewart, Margaret L Musser, Carol B Grindem. What is your diagnosis? Urine crystals in a dog. Veterinary clinical pathology. 2015 Dec; 44(4):613-4. doi: 10.1111/vcp.12296. [PMID: 26437206]
  • Hyeon-Kyu Go, Md Mahbubur Rahman, Gi-Beum Kim, Chong-Sam Na, Choon-Ho Song, Jin-Shang Kim, Shang-Jin Kim, Hyung-Sub Kang. Antidiabetic Effects of Yam (Dioscorea batatas) and Its Active Constituent, Allantoin, in a Rat Model of Streptozotocin-Induced Diabetes. Nutrients. 2015 Oct; 7(10):8532-44. doi: 10.3390/nu7105411. [PMID: 26501316]
  • Jeffery D Ray, Arun Prabhu Dhanapal, Shardendu K Singh, Valerio Hoyos-Villegas, James R Smith, Larry C Purcell, C Andy King, Debbie Boykin, Perry B Cregan, Qijian Song, Felix B Fritschi. Genome-Wide Association Study of Ureide Concentration in Diverse Maturity Group IV Soybean [Glycine max (L.) Merr.] Accessions. G3 (Bethesda, Md.). 2015 Sep; 5(11):2391-403. doi: 10.1534/g3.115.021774. [PMID: 26374596]
  • Jian-jun Li, Mei-ling Ren, Jun Wang, Guo-lun Jia, Li-xin Pei, Shu-wu Sun. [Research on Breeding of Dioscorea opposita cv. Tiegun]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Sep; 38(9):1787-91. doi: ". [PMID: 26930971]
  • Vesna Lj Savić, Vesna D Nikolić, Ivana A Arsić, Ljiljana P Stanojević, Stevo J Najman, Sanja Stojanović, Ivana I Mladenović-Ranisavljević. Comparative Study of the Biological Activity of Allantoin and Aqueous Extract of the Comfrey Root. Phytotherapy research : PTR. 2015 Aug; 29(8):1117-22. doi: 10.1002/ptr.5356. [PMID: 25880800]
  • Tingting Wei, Liangcai Zhao, Jianmin Jia, Huanhuan Xia, Yao Du, Qiuting Lin, Xiaodong Lin, Xinjian Ye, Zhihan Yan, Hongchang Gao. Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice. Scientific reports. 2015 Jul; 5(?):11998. doi: 10.1038/srep11998. [PMID: 26149603]