1,4-Dihydroxynaphthalene (BioDeep_00000010141)

 

Secondary id: BioDeep_00001873740

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


1,4-Dihydroxynaphthalene

化学式: C10H8O2 (160.0524268)
中文名称: 1,4-萘二酚
谱图信息: 最多检出来源 Homo sapiens(blood) 0.14%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=CC=C2O)O
InChI: InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H

描述信息

同义名列表

6 个代谢物同义名

1,4-Dihydroxynaphthalene; 1,4-Naphthohydroquinone; naphthalene-1,4-diol; 1,4-Naphthalenediol; BENZOHYDROQUINONE; 1,4-Dihydroxynaphthalene



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Si-Meng Zhao, Zhe Wang, Guang-Zhi Zeng, Wei-Wu Song, Xiao-Qiang Chen, Xiao-Nian Li, Ning-Hua Tan. New cytotoxic naphthohydroquinone dimers from Rubia alata. Organic letters. 2014 Nov; 16(21):5576-9. doi: 10.1021/ol502603f. [PMID: 25310176]
  • Da Ma, Gaya Hettiarachchi, Duc Nguyen, Ben Zhang, James B Wittenberg, Peter Y Zavalij, Volker Briken, Lyle Isaacs. Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals. Nature chemistry. 2012 Apr; 4(6):503-10. doi: 10.1038/nchem.1326. [PMID: 22614387]
  • Joel D Parry, Amy V Pointon, Ursula Lutz, Friederike Teichert, Joanne K Charlwood, Pui Hei Chan, Toby J Athersuch, Emma L Taylor, Rajinder Singh, Jinli Luo, Kate M Phillips, Angelique Vetillard, Jonathan J Lyon, Hector C Keun, Werner K Lutz, Timothy W Gant. Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress. Chemical research in toxicology. 2009 Apr; 22(4):717-25. doi: 10.1021/tx800472z. [PMID: 19338340]
  • Till Opatz, Heinz Kolshorn, Eckhard Thines, Heidrun Anke. Ascomycones A-C, heptaketide metabolites from an unidentified ascomycete. Journal of natural products. 2008 Nov; 71(11):1973-6. doi: 10.1021/np800570w. [PMID: 18989977]
  • Renan Wu, Suramya Waidyanatha, Alistair P Henderson, Berrin Serdar, Yuxin Zheng, Stephen M Rappaport. Determination of dihydroxynaphthalenes in human urine by gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Nov; 826(1-2):206-13. doi: 10.1016/j.jchromb.2005.08.022. [PMID: 16169295]
  • Heiko Rischer, Andreas Hamm, Gerhard Bringmann. Nepenthes insignis uses a C2-portion of the carbon skeleton of L-alanine acquired via its carnivorous organs, to build up the allelochemical plumbagin. Phytochemistry. 2002 Mar; 59(6):603-9. doi: 10.1016/s0031-9422(02)00003-1. [PMID: 11867092]
  • L S Tsuruda, M W Lamé, A D Jones. Formation of epoxide and quinone protein adducts in B6C3F1 mice treated with naphthalene, sulfate conjugate of 1,4-dihydroxynaphthalene and 1,4-naphthoquinone. Archives of toxicology. 1995; 69(6):362-7. doi: 10.1007/s002040050185. [PMID: 7495373]
  • K K Kaistha. Guide to urine testing in drug abuse prevention and multi-modality treatment programs. Journal of chromatography. 1977 Aug; 141(2):145-96. doi: 10.1016/s0021-9673(00)99132-5. [PMID: 19493]