Adenosine monophosphate (BioDeep_00000001261)

 

Secondary id: BioDeep_00001867750

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Chemicals and Drugs BioNovoGene_Lab2019


代谢物信息卡片


{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

化学式: C10H14N5O7P (347.0631)
中文名称: 單磷酸腺苷, 一磷酸腺苷, 单磷酸腺苷酸, 腺苷-5'-单磷酸 二钠盐, 5-腺苷酸
谱图信息: 最多检出来源 Homo sapiens(blood) 26.67%

Reviewed

Last reviewed on 2024-07-01.

Cite this Page

Adenosine monophosphate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/adenosine_monophosphate (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000001261). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O)N
InChI: InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)

描述信息

Adenosine monophosphate, also known as adenylic acid or amp, is a member of the class of compounds known as purine ribonucleoside monophosphates. Purine ribonucleoside monophosphates are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached. Adenosine monophosphate is slightly soluble (in water) and a moderately acidic compound (based on its pKa). Adenosine monophosphate can be found in a number of food items such as kiwi, taro, alaska wild rhubarb, and skunk currant, which makes adenosine monophosphate a potential biomarker for the consumption of these food products. Adenosine monophosphate can be found primarily in most biofluids, including blood, feces, cerebrospinal fluid (CSF), and urine, as well as throughout all human tissues. Adenosine monophosphate exists in all living species, ranging from bacteria to humans. In humans, adenosine monophosphate is involved in several metabolic pathways, some of which include josamycin action pathway, methacycline action pathway, nevirapine action pathway, and aspartate metabolism. Adenosine monophosphate is also involved in several metabolic disorders, some of which include hyperornithinemia-hyperammonemia-homocitrullinuria [hhh-syndrome], molybdenum cofactor deficiency, xanthinuria type I, and mitochondrial DNA depletion syndrome. Adenosine monophosphate is a drug which is used for nutritional supplementation, also for treating dietary shortage or imbalanc.
Adenosine monophosphate, also known as 5-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP can be produced during ATP synthesis by the enzyme adenylate kinase. AMP has recently been approved as a Bitter Blocker additive to foodstuffs. When AMP is added to bitter foods or foods with a bitter aftertaste it makes them seem sweeter. This potentially makes lower calorie food products more palatable.
[Spectral] AMP (exact mass = 347.06308) and Guanine (exact mass = 151.04941) and 3,4-Dihydroxy-L-phenylalanine (exact mass = 197.06881) and Glutathione disulfide (exact mass = 612.15196) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
[Spectral] AMP (exact mass = 347.06308) and Glutathione disulfide (exact mass = 612.15196) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
[Spectral] AMP (exact mass = 347.06308) and Adenine (exact mass = 135.0545) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.

Adenosine monophosphate. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=67583-85-1 (retrieved 2024-07-01) (CAS RN: 61-19-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

同义名列表

70 个代谢物同义名

{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid; [5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate; Adenosine 5-(dihydrogen phosphoric acid); Adenosine-5-monophosphate sodium salt; Adenosine 5-(dihydrogen phosphate); Dipotassium, adenosine phosphate; Phosphate dipotassium, adenosine; Adenosine-5-monophosphoric acid; 5-Adenosine monophosphoric acid; Adenosine phosphate dipotassium; Adenosine 5-monophosphoric acid; Adenosine monophosphoric acid; Disodium, adenosine phosphate; Phosphate disodium, adenosine; Adenosine phosphate disodium; Adenosine 5-phosphoric acid; Adenosine-5-monophosphorate; Phosphoric acid dadenosine; monoPhosphate, 2-adenosine; Adenosine-5-monophosphate; Adenosine phosphoric acid; 2 Adenosine monophosphate; 5-Adenosine monophosphate; 2-Adenosine monophosphate; Adenosine 5-monophosphate; Adenosine-monophosphate; Adenosine 5-phosphorate; Adenosine monophosphate; 5-Phosphate, adenosine; 5-O-Phosphonoadenosine; Adenosine 2 phosphate; Adenosine 2-phosphate; Adenosine 3 phosphate; Adenosine 3-phosphate; Adenosine 5 phosphate; Adenosine 5-phosphate; Fosfato de adenosina; Muscle adenylic acid; Phosphate dadenosine; Adenosine-phosphate; Adenosine phosphate; Adenosini phosphas; Acid, 5-adenylic; Acid, 2-adenylic; Muscle adenylate; 5 Adenylic acid; 2-Adenylic acid; 5-Adenylic acid; 2 Adenylic acid; Phosphentaside; Adenylic acid; Adenosine-5p; 5-Adenylate; My-beta-den; Cardiomone; Phosphaden; Adenovite; Adenylate; Phosaden; My-b-den; Lycedan; Adenyl; Ado5p; 2-AMP; 5-AMP; PAdo; AMP; pA; Adenosine monophosphate (AMP); AMP



数据库引用编号

61 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(7)

BioCyc(34)

PlantCyc(0)

代谢反应

2783 个相关的代谢反应过程信息。

Reactome(281)

BioCyc(74)

WikiPathways(7)

Plant Reactome(1771)

INOH(20)

PlantCyc(0)

COVID-19 Disease Map(1)

PathBank(629)

PharmGKB(0)

161 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ADA, ALB, ANXA5, BCL2, BDNF, CASP3, DCK, NFE2L2, NT5C2, PPARG, PTGS2
Peripheral membrane protein 3 ADA, ANXA5, PTGS2
Endoplasmic reticulum membrane 3 BCL2, HMOX1, PTGS2
Nucleus 8 ADK, ALB, BCL2, CASP3, DCK, HMOX1, NFE2L2, PPARG
cytosol 11 ADA, ADK, ALB, ANXA5, BCL2, CASP3, DCK, HMOX1, NFE2L2, NT5C2, PPARG
dendrite 1 BDNF
centrosome 2 ALB, NFE2L2
nucleoplasm 6 ADK, CASP3, DCK, HMOX1, NFE2L2, PPARG
RNA polymerase II transcription regulator complex 2 NFE2L2, PPARG
Cell membrane 2 ADA, TNF
Cytoplasmic side 1 HMOX1
cell junction 1 ADA
cell surface 3 ADA, EPCAM, TNF
glutamatergic synapse 1 CASP3
Golgi apparatus 2 ALB, NFE2L2
Golgi membrane 1 INS
neuronal cell body 2 CASP3, TNF
sarcolemma 1 ANXA5
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 2 NFE2L2, NT5C2
Lysosome 1 ADA
plasma membrane 6 ADA, ADK, EPCAM, IFNLR1, NFE2L2, TNF
Membrane 6 ADA, ANXA5, BCL2, BDNF, HMOX1, IFNLR1
apical plasma membrane 1 EPCAM
axon 1 BDNF
basolateral plasma membrane 1 EPCAM
caveola 1 PTGS2
extracellular exosome 3 ALB, ANXA5, EPCAM
endoplasmic reticulum 4 ALB, BCL2, HMOX1, PTGS2
extracellular space 8 ALB, BDNF, HMOX1, IL10, IL6, IL9, INS, TNF
perinuclear region of cytoplasm 3 BDNF, HMOX1, PPARG
Cell junction, tight junction 1 EPCAM
bicellular tight junction 1 EPCAM
mitochondrion 2 BCL2, DCK
protein-containing complex 3 ALB, BCL2, PTGS2
intracellular membrane-bounded organelle 1 PPARG
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 EPCAM, IFNLR1
Secreted 6 ALB, BDNF, IL10, IL6, IL9, INS
extracellular region 8 ALB, ANXA5, BDNF, IL10, IL6, IL9, INS, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 2 ADA, ALB
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 ADA, ANXA5, TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 ANXA5
collagen-containing extracellular matrix 1 ANXA5
lateral plasma membrane 1 EPCAM
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 PPARG
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 2 NFE2L2, PPARG
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
endosome lumen 1 INS
myelin sheath 1 BCL2
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 5 ALB, BDNF, IL6, INS, PTGS2
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
[Isoform 2]: Cytoplasm 1 ADK
vesicle membrane 1 ANXA5
[Isoform 1]: Nucleus 1 ADK
Lateral cell membrane 1 EPCAM
protein-DNA complex 1 NFE2L2
death-inducing signaling complex 1 CASP3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
interleukin-6 receptor complex 1 IL6
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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