cuminol (BioDeep_00000862734)

Main id: BioDeep_00000000992

 

PANOMIX_OTCML-2023 Antitumor activity Cytotoxicity natural product


代谢物信息卡片


InChI=1\C10H14O\c1-8(2)10-5-3-9(7-11)4-6-10\h3-6,8,11H,7H2,1-2H

化学式: C10H14O (150.1045)
中文名称: 4-异丙基苯甲醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C1=CC=C(C=C1)CO
InChI: InChI=1S/C10H14O/c1-8(2)10-5-3-9(7-11)4-6-10/h3-6,8,11H,7H2,1-2H3

描述信息

4-Isopropylbenzyl alcohol is a chemical composition of the essential oils from the leaves and flowers of Camellia nitidissima. C. nitidissima possess multiple biological activities including antioxidant activity, anticancer activity, and cytotoxicity as well as inhibiting the formation of advanced glycation end-products[1].
4-Isopropylbenzyl alcohol is a chemical composition of the essential oils from the leaves and flowers of Camellia nitidissima. C. nitidissima possess multiple biological activities including antioxidant activity, anticancer activity, and cytotoxicity as well as inhibiting the formation of advanced glycation end-products[1].

同义名列表

40 个代谢物同义名

InChI=1\C10H14O\c1-8(2)10-5-3-9(7-11)4-6-10\h3-6,8,11H,7H2,1-2H; 4-06-00-03348 (Beilstein Handbook Reference); Benzenemethanol, 4-(1-methylethyl)-; 4-(1-methylethyl)-benzenemethanol; 4-(1-methylethyl)benzene methanol; 4-(1-Methylethyl)benzenemethanol; (4-propan-2-ylphenyl)methanol; Benzyl alcohol, p-isopropyl-; (4-Isopropylphenyl)methanol; 4-ISOPROPYLBENZENEMETHANOL; p-Isopropylbenzyl alcohol; 4-Isopropylbenzyl alcohol; i>p\i>-Cumic alcohol; EINECS 208-640-4; cuminyl alcohol; p-cumic alcohol; W293318_ALDRICH; cuminic alcohol; WLN: Q1R DY1&1; Cuminylalcohol; 196037_ALDRICH; CUMIN ALCOHOL; FEMA No. 2933; Cumic alcohol; Cumyl alcohol; ZINC00968247; p-Cymen-7-ol; BRN 0636665; 185532-73-4; AI3-20440; ST5437505; NSC 15672; NSC15672; 536-60-7; CPD-1002; cuminol; C06576; c0376; p-Cumic alcohol; 4-Isopropylbenzyl alcohol



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

165 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ALB, CYP2E1, FGF7, FST, RELA, TXN, VEGFA
Peripheral membrane protein 2 CYP1B1, CYP2E1
Endosome membrane 1 HLA-DRB1
Endoplasmic reticulum membrane 4 CYP1A2, CYP1B1, CYP2E1, HLA-DRB1
Nucleus 8 ALB, ANKRD42, FST, GLRX, RELA, TXN, VEGFA, ZNF79
cytosol 5 ALB, GLRX, GSR, RELA, TXN
centrosome 1 ALB
nucleoplasm 2 RELA, TXN
Cell membrane 3 ADRB1, HLA-DRB1, TNF
Early endosome membrane 1 HLA-DRB1
Multi-pass membrane protein 1 ADRB1
cell surface 3 HLA-DRB1, TNF, VEGFA
glutamatergic synapse 1 RELA
Golgi apparatus 3 ALB, FGF7, VEGFA
Golgi membrane 2 HLA-DRB1, INS
lysosomal membrane 1 HLA-DRB1
mitochondrial inner membrane 2 ATP5ME, CYP2E1
neuronal cell body 1 TNF
postsynapse 1 FGF7
plasma membrane 4 ADRB1, BCHE, HLA-DRB1, TNF
Membrane 3 CYP1B1, HLA-DRB1, VEGFA
extracellular exosome 5 ALB, GLRX, GSR, HLA-DRB1, TXN
Lysosome membrane 1 HLA-DRB1
endoplasmic reticulum 2 ALB, VEGFA
extracellular space 8 ALB, BCHE, FGF7, FST, HLA-DRB1, INS, TNF, VEGFA
Schaffer collateral - CA1 synapse 1 ADRB1
adherens junction 1 VEGFA
mitochondrion 4 ATP5ME, BCO2, CYP1B1, GSR
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 3 CYP1A2, CYP1B1, CYP2E1
Microsome membrane 3 CYP1A2, CYP1B1, CYP2E1
Single-pass type I membrane protein 1 HLA-DRB1
Secreted 5 ALB, BCHE, INS, TXN, VEGFA
extracellular region 8 ALB, BCHE, FGF7, FST, INS, TNF, TXN, VEGFA
Single-pass membrane protein 1 HLA-DRB1
mitochondrial matrix 2 BCO2, GSR
anchoring junction 1 ALB
transcription regulator complex 1 RELA
external side of plasma membrane 3 GSR, HLA-DRB1, TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
Early endosome 1 ADRB1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Mitochondrion inner membrane 1 CYP2E1
Membrane raft 1 TNF
GABA-ergic synapse 1 FGF7
extracellular matrix 1 VEGFA
secretory granule 1 VEGFA
intermediate filament 1 HLA-DRB1
ciliary basal body 1 ALB
chromatin 1 RELA
Late endosome membrane 1 HLA-DRB1
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 HLA-DRB1
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, BCHE
Recycling endosome membrane 1 HLA-DRB1
endosome lumen 1 INS
trans-Golgi network membrane 1 HLA-DRB1
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, BCHE, INS
platelet alpha granule lumen 2 ALB, VEGFA
endocytic vesicle membrane 1 HLA-DRB1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 HLA-DRB1
neuronal dense core vesicle 1 ADRB1
ER to Golgi transport vesicle membrane 1 HLA-DRB1
nuclear envelope lumen 1 BCHE
clathrin-coated endocytic vesicle membrane 1 HLA-DRB1
lumenal side of endoplasmic reticulum membrane 1 HLA-DRB1
proton-transporting ATP synthase complex 1 ATP5ME
proton-transporting ATP synthase complex, coupling factor F(o) 1 ATP5ME
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Autolysosome membrane 1 HLA-DRB1
MHC class II protein complex 1 HLA-DRB1
transport vesicle membrane 1 HLA-DRB1
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
NF-kappaB p50/p65 complex 1 RELA
NF-kappaB complex 1 RELA
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Mohd Sajid Ali, Md Tabish Rehman, Hamad A Al-Lohedan, Mohamed Fahad AlAjmi. Exploration of the binding between cuminol and bovine serum albumin through spectroscopic, molecular docking and molecular dynamics methods. Journal of biomolecular structure & dynamics. 2022; 40(22):12404-12412. doi: 10.1080/07391102.2021.1971560. [PMID: 34488560]
  • Iveta Bartoňková, Zdeněk Dvořák. Essential oils of culinary herbs and spices display agonist and antagonist activities at human aryl hydrocarbon receptor AhR. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018 Jan; 111(?):374-384. doi: 10.1016/j.fct.2017.11.049. [PMID: 29191726]
  • Swapnil B Patil, Shreehari S Takalikar, Madhav M Joglekar, Vivek S Haldavnekar, Akalpita U Arvindekar. Insulinotropic and β-cell protective action of cuminaldehyde, cuminol and an inhibitor isolated from Cuminum cyminum in streptozotocin-induced diabetic rats. The British journal of nutrition. 2013 Oct; 110(8):1434-43. doi: 10.1017/s0007114513000627. [PMID: 23507295]
  • Mansouria Souria Bendeddouche, Hachemi Benhassaini, Zouaoui Hazem, Abderrahmane Romane. Essential oil analysis and antibacterial activity of Rosmarinus tournefortii from Algeria. Natural product communications. 2011 Oct; 6(10):1511-4. doi: . [PMID: 22164796]
  • Christy E Manyi-Loh, Roland N Ndip, Anna M Clarke. Volatile compounds in honey: a review on their involvement in aroma, botanical origin determination and potential biomedical activities. International journal of molecular sciences. 2011; 12(12):9514-32. doi: 10.3390/ijms12129514. [PMID: 22272147]
  • R J W Meesters, M Duisken, J Hollender. Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p-cymene: indication for the formation of a reactive allergenic intermediate?. Xenobiotica; the fate of foreign compounds in biological systems. 2009 Sep; 39(9):663-71. doi: 10.1080/00498250902989094. [PMID: 19480554]