2-Hydroxyestradiol (BioDeep_00000405244)

Main id: BioDeep_00000637477

 

natural product


代谢物信息卡片


2-Hydroxyestradiol

化学式: C18H24O3 (288.1725)
中文名称: 2-羟基-17β-雌二醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)O)O
InChI: InChI=1S/C18H24O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,17,19-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1

描述信息

C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones

同义名列表

2 个代谢物同义名

2-Hydroxyestradiol; 2-Hydroxyestradiol



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADCY10, CAT, CYP1A1, CYP3A4, ESR1, GPER1, TH, TYR, VEGFA
Peripheral membrane protein 4 ADCY10, CYP1A1, CYP1B1, ESR1
Endoplasmic reticulum membrane 6 CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, GPER1
Mitochondrion membrane 1 GPER1
Nucleus 7 ADCY10, ESR1, ESR2, GPER1, PCNA, TH, VEGFA
cytosol 6 ADCY10, CAT, COMT, ESR1, GPER1, TH
dendrite 4 ADCY10, COMT, GPER1, TH
mitochondrial membrane 1 GPER1
nuclear body 1 PCNA
trans-Golgi network 1 GPER1
centrosome 1 PCNA
nucleoplasm 4 ESR1, ESR2, GPER1, PCNA
Cell membrane 4 ADCY10, ADRB3, COMT, ESR1
Cytoplasmic side 2 ADCY10, ESR1
Cell projection, axon 2 GPER1, TH
Multi-pass membrane protein 4 ADRB3, CYP19A1, GPER1, SLC45A2
Golgi apparatus membrane 1 GPER1
Synapse 1 COMT
cell surface 1 VEGFA
dendritic shaft 1 GPER1
Golgi apparatus 3 ESR1, GPER1, VEGFA
Golgi membrane 2 GPER1, INS
mitochondrial inner membrane 1 CYP1A1
neuronal cell body 1 ADCY10
presynaptic membrane 1 GPER1
smooth endoplasmic reticulum 1 TH
synaptic vesicle 1 TH
Lysosome 1 TYR
plasma membrane 4 ADRB3, COMT, ESR1, GPER1
presynaptic active zone 1 GPER1
terminal bouton 1 TH
Membrane 9 CAT, COMT, CYP19A1, CYP1B1, CYP3A4, ESR1, GPER1, SLC45A2, VEGFA
apical plasma membrane 1 ADCY10
axon 3 COMT, GPER1, TH
extracellular exosome 4 CAT, COMT, PCNA, SHBG
endoplasmic reticulum 3 CYP19A1, GPER1, VEGFA
extracellular space 2 INS, VEGFA
perinuclear region of cytoplasm 4 ADCY10, GPER1, TH, TYR
adherens junction 1 VEGFA
mitochondrion 6 ADCY10, CAT, CYP1A1, CYP1B1, ESR2, TH
protein-containing complex 2 CAT, ESR1
intracellular membrane-bounded organelle 9 CAT, COMT, CYP1A1, CYP1A2, CYP1B1, CYP3A4, ESR2, GPER1, TYR
Microsome membrane 5 CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4
postsynaptic density 1 GPER1
Single-pass type I membrane protein 1 TYR
Secreted 3 INS, SHBG, VEGFA
extracellular region 5 ADCY10, CAT, INS, SHBG, VEGFA
cytoplasmic side of plasma membrane 1 TH
astrocyte end-foot 1 ADCY10
basal part of cell 1 ADCY10
central region of growth cone 1 ADCY10
hippocampal mossy fiber to CA3 synapse 1 GPER1
mitochondrial matrix 1 CAT
Extracellular side 1 COMT
transcription regulator complex 1 ESR1
Cell projection, cilium 1 ADCY10
Secreted, extracellular space, extracellular matrix 1 VEGFA
perikaryon 1 TH
cytoplasmic vesicle 1 TH
nucleolus 1 GPER1
Melanosome membrane 3 SLC45A2, TH, TYR
Early endosome 1 GPER1
Golgi-associated vesicle 1 TYR
recycling endosome 1 GPER1
Single-pass type II membrane protein 1 COMT
Cytoplasm, perinuclear region 2 ADCY10, TH
Mitochondrion inner membrane 1 CYP1A1
Cytoplasm, cytoskeleton 1 ADCY10
focal adhesion 1 CAT
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 VEGFA
receptor complex 1 ADRB3
neuron projection 1 TH
cilium 1 ADCY10
chromatin 3 ESR1, ESR2, PCNA
cytoskeleton 1 ADCY10
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
nuclear envelope 1 GPER1
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 GPER1
Cell projection, dendrite 1 GPER1
Melanosome 1 TYR
euchromatin 1 ESR1
replication fork 1 PCNA
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
male germ cell nucleus 1 PCNA
platelet alpha granule lumen 1 VEGFA
axon terminus 1 GPER1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
nuclear lamina 1 PCNA
[Isoform 1]: Nucleus 1 ESR1
keratin filament 1 GPER1
dendritic spine head 1 GPER1
Cell projection, dendritic spine membrane 1 GPER1
dendritic spine membrane 1 GPER1
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
catalase complex 1 CAT
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT


文献列表

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