N-Acetylserotonin (BioDeep_00000400007)

Main id: BioDeep_00000001293

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


N-Acetyl-5-hydroxytryptamine

化学式: C12H14N2O2 (218.1055)
中文名称: N-乙酰-5-羟基色胺, N-乙酰基-5-羟色胺
谱图信息: 最多检出来源 Homo sapiens(blood) 44.21%

分子结构信息

SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)O
InChI: InChI=1S/C12H14N2O2/c1-8(15)13-5-4-9-7-14-12-3-2-10(16)6-11(9)12/h2-3,6-7,14,16H,4-5H2,1H3,(H,13,15)

描述信息

An N-acylserotonin resulting from the formal condensation of the primary amino group of serotonin with the carboxy group of acetic acid.
N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor.

同义名列表

6 个代谢物同义名

N-Acetylserotonin; N-Acetyl-5-hydroxytryptamine; Normelatonin; O-Demethylmelatonin; N-Acetylserotonin; N-Acetyl-5-hydroxytryptamine



数据库引用编号

33 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(3)

BioCyc(4)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 AANAT, AHR, BCL2, BDNF, CASP3, MT3, NLRP3, NOS2, NTRK2, PIK3CA, SPR, SQSTM1, TLR4
Peripheral membrane protein 1 CYP1B1
Endosome membrane 2 NTRK2, TLR4
Endoplasmic reticulum membrane 2 BCL2, CYP1B1
Cytoplasmic vesicle, autophagosome 1 SQSTM1
Nucleus 8 AHR, BCL2, CASP3, GABPA, MT3, NLRP3, NOS2, SQSTM1
autophagosome 1 SQSTM1
cytosol 14 AANAT, AHR, ASMT, BCL2, CASP3, COMT, MT3, NLRP3, NOS2, NTRK2, PIK3CA, SPR, SQSTM1, TDO2
dendrite 3 BDNF, COMT, NTRK2
nucleoplasm 6 AHR, CASP3, GABPA, NOS2, SPR, SQSTM1
Cell membrane 4 COMT, MTNR1A, NTRK2, TLR4
lamellipodium 1 PIK3CA
Cell projection, axon 1 NTRK2
Early endosome membrane 1 NTRK2
Multi-pass membrane protein 1 MTNR1A
Golgi apparatus membrane 1 NLRP3
Synapse 1 COMT
cell surface 1 TLR4
glutamatergic synapse 2 CASP3, SQSTM1
Golgi membrane 1 NLRP3
neuronal cell body 1 CASP3
synaptic vesicle 2 BDNF, MT3
Cytoplasm, cytosol 3 NLRP3, NOS2, SQSTM1
Lysosome 1 SQSTM1
plasma membrane 7 COMT, IFNLR1, MTNR1A, NOS2, NTRK2, PIK3CA, TLR4
terminal bouton 1 NTRK2
Membrane 8 BCL2, BDNF, COMT, CYP1B1, IFNLR1, NLRP3, NTRK2, TLR4
axon 4 BDNF, COMT, MT3, NTRK2
extracellular exosome 3 COMT, SPR, SQSTM1
endoplasmic reticulum 3 BCL2, NLRP3, SQSTM1
extracellular space 2 BDNF, MT3
perinuclear region of cytoplasm 7 AANAT, BDNF, MT3, NOS2, NTRK2, PIK3CA, TLR4
intercalated disc 1 PIK3CA
mitochondrion 5 BCL2, CYP1B1, NLRP3, SPR, SQSTM1
protein-containing complex 2 AHR, BCL2
intracellular membrane-bounded organelle 3 COMT, CYP1B1, SQSTM1
Microsome membrane 1 CYP1B1
postsynaptic density 2 CASP3, NTRK2
Single-pass type I membrane protein 3 IFNLR1, NTRK2, TLR4
Secreted 2 BDNF, NLRP3
extracellular region 2 BDNF, NLRP3
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, MT3
astrocyte end-foot 1 MT3
Extracellular side 1 COMT
transcription regulator complex 1 AHR
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TLR4
dendritic spine 2 MT3, NTRK2
cytoplasmic vesicle 1 SQSTM1
Cytoplasm, P-body 1 NOS2
P-body 2 NOS2, SQSTM1
Early endosome 2 NTRK2, TLR4
Single-pass type II membrane protein 1 COMT
Cytoplasm, perinuclear region 2 NOS2, NTRK2
pore complex 1 BCL2
microtubule 1 MT3
Peroxisome 1 NOS2
peroxisomal matrix 1 NOS2
Nucleus, PML body 1 SQSTM1
PML body 1 SQSTM1
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
Cell projection, ruffle 1 TLR4
Cytoplasm, myofibril, sarcomere 1 SQSTM1
Late endosome 1 SQSTM1
ruffle 1 TLR4
sarcomere 1 SQSTM1
receptor complex 3 MTNR1A, NTRK2, TLR4
chromatin 2 AHR, GABPA
phagocytic cup 1 TLR4
sperm midpiece 1 SQSTM1
Endomembrane system 1 NLRP3
microtubule organizing center 1 NLRP3
phagophore assembly site 1 SQSTM1
aryl hydrocarbon receptor complex 1 AHR
Cell projection, dendrite 1 NTRK2
myelin sheath 1 BCL2
lipopolysaccharide receptor complex 1 TLR4
endoplasmic reticulum lumen 1 BDNF
axon terminus 1 NTRK2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
aggresome 1 SQSTM1
death-inducing signaling complex 1 CASP3
intracellular non-membrane-bounded organelle 1 SQSTM1
Lewy body 1 SQSTM1
Preautophagosomal structure 1 SQSTM1
ribosome 1 MT3
cortical cytoskeleton 1 NOS2
Autolysosome 1 SQSTM1
inclusion body 2 MT3, SQSTM1
BAD-BCL-2 complex 1 BCL2
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
interleukin-28 receptor complex 1 IFNLR1
amphisome 1 SQSTM1


文献列表

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