Mirex (BioDeep_00000009745)
Secondary id: BioDeep_00001873579
human metabolite Endogenous blood metabolite Industrial Pollutants
代谢物信息卡片
化学式: C10Cl12 (539.6262)
中文名称: 灭蚁灵
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C12(C3(C4(C5(C(C1(C4(Cl)Cl)Cl)(C2(C(C35Cl)(Cl)Cl)Cl)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C10Cl12/c11-1-2(12)7(17)4(14)3(13,5(1,15)9(7,19)20)6(1,16)10(21,22)8(2,4)18
描述信息
Mirex is a chlorinated hydrocarbon that was commercialized as an insecticide and later banned because of its impact on the environment. This white crystalline odorless solid is a derivative of cyclopentadiene. It was popularized to control fire ants but by virtue of its chemical robustness and lipophilicity it was recognized as a bioaccumulative pollutant. Ironically, the spread of the red imported fire ant was actually encouraged by the use of Mirex, which also kills native ants that are highly competitive with the fire ants. The United States Environmental Protection Agency prohibited its use in 1976.
同义名列表
10 个代谢物同义名
1,2,3,4,5,5,6,7,8,9,10,10-Dodecachloropentacyclo[5.3.0.0(2,6).0(3,9).0(4,8)]decane; Dodecachlorooctahydro-1,3,4-metheno-2H-cyclobuta[CD]pentalene; Perchloropentacyclo[5.2.1.0(2,6).0(3,9).0(5,8)]decane; dodecachloropentacyclo[5.3.0.0²,⁶.0³,⁹.0⁴,⁸]decane; Perchloropentacyclodecane; Perchlorodihomocubane; Dechlorane; CG-1283; MIREX; Mirex
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:34852
- KEGG: C14184
- PubChem: 16945
- HMDB: HMDB0059573
- Metlin: METLIN69859
- ChEMBL: CHEMBL442231
- Wikipedia: Mirex
- MeSH: Mirex
- chemspider: 16054
- CAS: 2385-85-5
- PMhub: MS000023562
- PubChem: 7846994
- NIKKAJI: J8.588J
- RefMet: Mirex
- KNApSAcK: 34852
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Nara Oliveira-Ferreira, Bárbara M R Manhães, Elitieri Santos-Neto, Rafael Ramos Carvalho, Haydée Andrade Cunha, Alexandre Freitas Azevedo, Tatiana Lemos Bisi, José Lailson-Brito. Organohalogen compounds in a hotspot for chemical pollution: Assessment in free-ranging Atlantic spotted dolphins (Stenella frontalis).
The Science of the total environment.
2024 May; 926(?):171912. doi:
10.1016/j.scitotenv.2024.171912
. [PMID: 38522545] - Rosalinda C Montone, Mariana B Alonso, Marcos César O Santos, Paula Méndez-Fernandez, Satie Taniguchi, Ana Paula M Barbosa, Renato M Gonçalves, Janeide de Assis Padilha, Carolina Bertozzi, Josilene da Silva, Juliana Marigo, Antonio Derley S Pereira, Rafael A Lourenço. Temporal trends of persistent organic pollutant contamination in Franciscana dolphins from the Southwestern Atlantic.
Environmental research.
2023 01; 216(Pt 1):114473. doi:
10.1016/j.envres.2022.114473
. [PMID: 36195158] - Yukiko Fujii, Kouji H Harada, Yoshiko Ito, Miho Yoshitake, Chiharu Matsunobu, Yoshihisa Kato, Chiho Ohta, Nobuyuki Koga, Osamu Kimura, Tetsuya Endo, Akio Koizumi, Koichi Haraguchi. Profiles and determinants of dicofol, endosulfans, mirex, and toxaphenes in breast milk samples from 10 prefectures in Japan.
Chemosphere.
2023 Jan; 311(Pt 1):137002. doi:
10.1016/j.chemosphere.2022.137002
. [PMID: 36419270] - Zafar Aminov, Richard Haase, David O Carpenter. Diabetes in Native Americans: elevated risk as a result of exposure to polychlorinated biphenyls (PCBs).
Reviews on environmental health.
2016 Mar; 31(1):115-9. doi:
10.1515/reveh-2015-0054
. [PMID: 26943594] - Li Shen, Karl J Jobst, Eric J Reiner, Paul A Helm, Robert McCrindle, Vince Y Taguchi, Chris H Marvin, Sean Backus, Karen A MacPherson, Ian D Brindle. Identification and occurrence of analogues of dechlorane 604 in Lake Ontario sediment and their accumulation in fish.
Environmental science & technology.
2014 Oct; 48(19):11170-7. doi:
10.1021/es503089c
. [PMID: 25184555] - Duan Gui, Riqing Yu, Xuan He, Qin Tu, Yuping Wu. Tissue distribution and fate of persistent organic pollutants in Indo-Pacific humpback dolphins from the Pearl River Estuary, China.
Marine pollution bulletin.
2014 Sep; 86(1-2):266-273. doi:
10.1016/j.marpolbul.2014.07.007
. [PMID: 25066456] - Huan Guo, Yinlong Jin, Yibin Cheng, Brian Leaderer, Shaobin Lin, Theodore R Holford, Jie Qiu, Yawei Zhang, Kunchong Shi, Yong Zhu, Jianjun Niu, Bryan A Bassig, Shunqing Xu, Bin Zhang, Yonghong Li, Xiaobin Hu, Qiong Chen, Tongzhang Zheng. Prenatal exposure to organochlorine pesticides and infant birth weight in China.
Chemosphere.
2014 Sep; 110(?):1-7. doi:
10.1016/j.chemosphere.2014.02.017
. [PMID: 24880592] - Kristen Upson, Anneclaire J De Roos, Mary Lou Thompson, Sheela Sathyanarayana, Delia Scholes, Dana Boyd Barr, Victoria L Holt. Organochlorine pesticides and risk of endometriosis: findings from a population-based case-control study.
Environmental health perspectives.
2013 Nov; 121(11-12):1319-24. doi:
10.1289/ehp.1306648
. [PMID: 24192044] - Xiao Yan, Jing Zheng, Ke-Hui Chen, Junzhi Yang, Xiao-Jun Luo, Le-Huan Yu, She-Jun Chen, Bi-Xian Mai, Zhong-Yi Yang. Dechlorane Plus in serum from e-waste recycling workers: influence of gender and potential isomer-specific metabolism.
Environment international.
2012 Nov; 49(?):31-7. doi:
10.1016/j.envint.2012.08.011
. [PMID: 22982220] - Li Shen, Karl J Jobst, Paul A Helm, Eric J Reiner, Robert McCrindle, Gregg T Tomy, Sean Backus, Ian D Brindle, Chris H Marvin. Identification and determination of the dechlorination products of Dechlorane 602 in Great Lakes fish and Arctic beluga whales by gas chromatography-high resolution mass spectrometry.
Analytical and bioanalytical chemistry.
2012 Nov; 404(9):2737-48. doi:
10.1007/s00216-012-6164-7
. [PMID: 22718042] - Susan L Klosterhaus, Heather M Stapleton, Mark J La Guardia, Denise J Greig. Brominated and chlorinated flame retardants in San Francisco Bay sediments and wildlife.
Environment international.
2012 Oct; 47(?):56-65. doi:
10.1016/j.envint.2012.06.005
. [PMID: 22766500] - Bing Wu, Su Liu, Xuechao Guo, Yan Zhang, Xuxiang Zhang, Mei Li, Shupei Cheng. Responses of mouse liver to dechlorane plus exposure by integrative transcriptomic and metabonomic studies.
Environmental science & technology.
2012 Oct; 46(19):10758-64. doi:
10.1021/es301804t
. [PMID: 22913625] - Yuxin Sun, Xiaojun Luo, Jiangping Wu, Ling Mo, Shejun Chen, Qiang Zhang, Fasheng Zou, Bixian Mai. Species- and tissue-specific accumulation of Dechlorane Plus in three terrestrial passerine bird species from the Pearl River Delta, South China.
Chemosphere.
2012 Oct; 89(4):445-51. doi:
10.1016/j.chemosphere.2012.05.089
. [PMID: 22727895] - Luo Wang, Hongliang Jia, Xianjie Liu, Meng Yang, Wenjun Hong, Yeqing Sun, Yushan Su, Hong Qi, Weiwei Song, Jun Lin, Yi-Fan Li. Dechloranes in a river in northeastern China: spatial trends in multi-matrices and bioaccumulation in fish (Enchelyopus elongatus).
Ecotoxicology and environmental safety.
2012 Oct; 84(?):262-7. doi:
10.1016/j.ecoenv.2012.07.018
. [PMID: 22863566] - Hui Peng, Kun Zhang, Yi Wan, Jianying Hu. Tissue distribution, maternal transfer, and age-related accumulation of dechloranes in Chinese sturgeon.
Environmental science & technology.
2012 Sep; 46(18):9907-13. doi:
10.1021/es3025879
. [PMID: 22913883] - Xiao-Bo Zheng, Jiang-Ping Wu, Xiao-Jun Luo, Yan-Hong Zeng, Ya-Zhe She, Bi-Xian Mai. Halogenated flame retardants in home-produced eggs from an electronic waste recycling region in South China: levels, composition profiles, and human dietary exposure assessment.
Environment international.
2012 Sep; 45(?):122-8. doi:
10.1016/j.envint.2012.04.006
. [PMID: 22609680] - Shabana Siddique, Qiming Xian, Nadia Abdelouahab, Larissa Takser, Susan P Phillips, Yong-Lai Feng, Bing Wang, Jiping Zhu. Levels of dechlorane plus and polybrominated diphenylethers in human milk in two Canadian cities.
Environment international.
2012 Feb; 39(1):50-5. doi:
10.1016/j.envint.2011.09.010
. [PMID: 22208742] - Ed Sverko, Gregg T Tomy, Eric J Reiner, Yi-Fan Li, Brian E McCarry, Jon A Arnot, Robin J Law, Ronald A Hites. Dechlorane plus and related compounds in the environment: a review.
Environmental science & technology.
2011 Jun; 45(12):5088-98. doi:
10.1021/es2003028
. [PMID: 21574656] - Marta Venier, Ronald A Hites. Flame retardants in the serum of pet dogs and in their food.
Environmental science & technology.
2011 May; 45(10):4602-8. doi:
10.1021/es1043529
. [PMID: 21500827] - Yuan Wang, Margaret B Murphy, James C W Lam, Liping Jiao, Captain C L Wong, Leo W Y Yeung, Paul K S Lam. Polychlorinated biphenyls and organochlorine pesticides in local waterbird eggs from Hong Kong: risk assessment to local waterbirds.
Chemosphere.
2011 May; 83(7):891-6. doi:
10.1016/j.chemosphere.2011.02.073
. [PMID: 21440927] - She-Jun Chen, Mi Tian, Jing Wang, Tian Shi, Yong Luo, Xiao-Jun Luo, Bi-Xian Mai. Dechlorane Plus (DP) in air and plants at an electronic waste (e-waste) site in South China.
Environmental pollution (Barking, Essex : 1987).
2011 May; 159(5):1290-6. doi:
10.1016/j.envpol.2011.01.026
. [PMID: 21324409] - Michel Aubé, Christian Larochelle, Pierre Ayotte. Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
Environmental research.
2011 Apr; 111(3):337-47. doi:
10.1016/j.envres.2011.01.010
. [PMID: 21295777] - Xiu-Lan Zhang, Xiao-Jun Luo, Hong-Ying Liu, Le-Huan Yu, She-Jun Chen, Bi-Xian Mai. Bioaccumulation of several brominated flame retardants and dechlorane plus in waterbirds from an e-waste recycling region in South China: associated with trophic level and diet sources.
Environmental science & technology.
2011 Jan; 45(2):400-5. doi:
10.1021/es102251s
. [PMID: 21128659] - De-Gao Wang, Meng Yang, Hong Qi, Ed Sverko, Wan-Li Ma, Yi-Fan Li, Mehran Alaee, Eric J Reiner, Li Shen. An Asia-specific source of dechlorane plus: concentration, isomer profiles, and other related compounds.
Environmental science & technology.
2010 Sep; 44(17):6608-13. doi:
10.1021/es101224y
. [PMID: 20681512] - Amina Salamova, Ronald A Hites. Evaluation of tree bark as a passive atmospheric sampler for flame retardants, PCBs, and organochlorine pesticides.
Environmental science & technology.
2010 Aug; 44(16):6196-201. doi:
10.1021/es101599h
. [PMID: 20704217] - Marta Venier, Michael Wierda, William W Bowerman, Ronald A Hites. Flame retardants and organochlorine pollutants in bald eagle plasma from the Great Lakes region.
Chemosphere.
2010 Aug; 80(10):1234-40. doi:
10.1016/j.chemosphere.2010.05.043
. [PMID: 20579684] - Jung-Ho Kang, Jong-Chul Kim, Guang-Zhu Jin, Hyokeun Park, Song-Yee Baek, Yoon-Seok Chang. Detection of Dechlorane Plus in fish from urban-industrial rivers.
Chemosphere.
2010 May; 79(8):850-4. doi:
10.1016/j.chemosphere.2010.02.051
. [PMID: 20303139] - Ying Zhang, Xiao-Jun Luo, Jiang-Ping Wu, Juan Liu, Jing Wang, She-Jun Chen, Bi-Xian Mai. Contaminant pattern and bioaccumulation of legacy and emerging organhalogen pollutants in the aquatic biota from an e-waste recycling region in South China.
Environmental toxicology and chemistry.
2010 Apr; 29(4):852-9. doi:
10.1002/etc.122
. [PMID: 20821514] - Jiang-Ping Wu, Ying Zhang, Xiao-Jun Luo, Jing Wang, She-Jun Chen, Yun-Tao Guan, Bi-Xian Mai. Isomer-specific bioaccumulation and trophic transfer of Dechlorane Plus in the freshwater food web from a highly contaminated site, South China.
Environmental science & technology.
2010 Jan; 44(2):606-11. doi:
10.1021/es902744b
. [PMID: 19994895] - Li Shen, Eric J Reiner, Karen A MacPherson, Terry M Kolic, Ed Sverko, Paul A Helm, Satyendra P Bhavsar, Ian D Brindle, Chris H Marvin. Identification and screening analysis of halogenated norbornene flame retardants in the Laurentian Great Lakes: Dechloranes 602, 603, and 604.
Environmental science & technology.
2010 Jan; 44(2):760-6. doi:
10.1021/es902482b
. [PMID: 20000816] - Guofa Ren, Zhiqiang Yu, Shengtao Ma, Huiru Li, Pingan Peng, Guoying Sheng, Jiamo Fu. Determination of Dechlorane Plus in serum from electronics dismantling workers in South China.
Environmental science & technology.
2009 Dec; 43(24):9453-7. doi:
10.1021/es901672m
. [PMID: 20000543] - Gregg T Tomy, Caden R Thomas, Thane M Zidane, Kathryn E Murison, Kerri Pleskach, Jonathon Hare, Gilles Arsenault, Chris H Marvin, Ed Sverko. Examination of isomer specific bioaccumulation parameters and potential in vivo hepatic metabolites of syn- and anti-Dechlorane Plus isomers in juvenile rainbow trout (Oncorhynchus mykiss).
Environmental science & technology.
2008 Aug; 42(15):5562-7. doi:
10.1021/es800220y
. [PMID: 18754476] - Xinghua Qiu, Ronald A Hites. Dechlorane plus and other flame retardants in tree bark from the northeastern United States.
Environmental science & technology.
2008 Jan; 42(1):31-6. doi:
10.1021/es072039a
. [PMID: 18350871] - Kellyn Betts. New data on a widely used flame retardant.
Environmental science & technology.
2008 Jan; 42(1):5-6. doi:
"
. [PMID: 18350866] - Neculai Codru, Maria J Schymura, Serban Negoita, Robert Rej, David O Carpenter. Diabetes in relation to serum levels of polychlorinated biphenyls and chlorinated pesticides in adult Native Americans.
Environmental health perspectives.
2007 Oct; 115(10):1442-7. doi:
10.1289/ehp.10315
. [PMID: 17938733] - Carol J Belfiore, Raymond S H Yang, Laura S Chubb, Manupat Lohitnavy, Ornrat S Lohitnavy, Melvin E Andersen. Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling.
Toxicology.
2007 May; 234(1-2):59-72. doi:
10.1016/j.tox.2007.02.002
. [PMID: 17382449] - Gregg T Tomy, Kerri Pleskach, Nargis Ismail, D Michael Whittle, Paul A Helm, Ed Sverko, Donna Zaruk, Chris H Marvin. Isomers of dechlorane plus in Lake Winnipeg and Lake Ontario food webs.
Environmental science & technology.
2007 Apr; 41(7):2249-54. doi:
10.1021/es062781v
. [PMID: 17438771] - Michael S Bloom, John E Vena, Mya K Swanson, Kirsten B Moysich, James R Olson. Profiles of ortho-polychlorinated biphenyl congeners, dichlorodiphenyldichloroethylene, hexachlorobenzene, and Mirex among male Lake Ontario sportfish consumers: the New York State Angler cohort study.
Environmental research.
2005 Feb; 97(2):178-94. doi:
10.1016/j.envres.2004.06.001
. [PMID: 15533334] - Michael S Bloom, John M Weiner, John E Vena, Gregory P Beehler. Exploring associations between serum levels of select organochlorines and thyroxine in a sample of New York state sportsmen: the New York State Angler Cohort Study.
Environmental research.
2003 Sep; 93(1):52-66. doi:
10.1016/s0013-9351(02)00085-3
. [PMID: 12865048] - Karen L Porter, Sanjay Chanda, Hui Quin Wang, Kevin W Gaido, Robert C Smart, C Lee Robinette. 17beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice.
Toxicological sciences : an official journal of the Society of Toxicology.
2002 Sep; 69(1):42-8. doi:
10.1093/toxsci/69.1.42
. [PMID: 12215659] - Yasuhiro Kimura, Yasuo Nagata, Carron W Bryant, Randal K Buddington. Nondigestible oligosaccharides do not increase accumulation of lipid soluble environmental contaminants by mice.
The Journal of nutrition.
2002 Jan; 132(1):80-7. doi:
10.1093/jn/132.1.80
. [PMID: 11773512] - A G Frenich, J L Vidal, M M Frías, F Olea-Serrano, N Olea. Quantitative determination of endocrine- disrupting polychlorinated biphenyls and organochlorinated pesticides in human serum using gas chromatography with electron-capture detection and tandem mass spectrometry.
Journal of mass spectrometry : JMS.
2000 Aug; 35(8):967-75. doi:
10.1002/1096-9888(200008)35:8<967::aid-jms24>3.0.co;2-v
. [PMID: 10972996] - J G Machado-Neto, M E Queiroz, D Carvalho, A J Bassini. Risk of intoxication with sulfluramid in a packing plant of Mirex-S.
Bulletin of environmental contamination and toxicology.
1999 May; 62(5):515-9. doi:
10.1007/s001289900906
. [PMID: 10227829] - H B Greizerstein, C Stinson, P Mendola, G M Buck, P J Kostyniak, J E Vena. Comparison of PCB congeners and pesticide levels between serum and milk from lactating women.
Environmental research.
1999 Apr; 80(3):280-6. doi:
10.1006/enrs.1999.3956
. [PMID: 10092447] - J P Kearney, D C Cole, L A Ferron, J P Weber. Blood PCB, p,p'-DDE, and mirex levels in Great Lakes fish and waterfowl consumers in two Ontario communities.
Environmental research.
1999 Feb; 80(2 Pt 2):S138-S149. doi:
10.1006/enrs.1998.3927
. [PMID: 10092427] - D M Owens, T A Zainal, A M Jetten, R C Smart. Localization and expression of cornifin-alpha/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasms.
The Journal of investigative dermatology.
1996 Apr; 106(4):647-54. doi:
10.1111/1523-1747.ep12345463
. [PMID: 8617999] - K N Thakore, H M Mehendale. Effect of phenobarbital and mirex pretreatments on CCl4 autoprotection.
Toxicologic pathology.
1994 May; 22(3):291-9. doi:
10.1177/019262339402200307
. [PMID: 7817119] - P R Kodavanti, U P Kodavanti, O M Faroon, H M Mehendale. Pivotal role of hepatocellular regeneration in the ultimate hepatotoxicity of CCl4 in chlordecone-, mirex-, or phenobarbital-pretreated rats.
Toxicologic pathology.
1992; 20(4):556-69. doi:
10.1177/019262339202000402
. [PMID: 1284994] - M P Korver, V W Burse, L L Needham, V E Green, D L Gray, M A Rouse, T L Shelly, B K Mortensen. Determination of Mirex in human blood serum containing polychlorinated biphenyls by using packed column gas chromatography.
Journal - Association of Official Analytical Chemists.
1991 Sep; 74(5):875-7. doi:
NULL
. [PMID: 1783595] - K N Thakore, M L Gargas, M E Andersen, H M Mehendale. PB-PK derived metabolic constants, hepatotoxicity, and lethality of BrCCl3 in rats pretreated with chlordecone, phenobarbital, or mirex.
Toxicology and applied pharmacology.
1991 Jul; 109(3):514-28. doi:
10.1016/0041-008x(91)90014-6
. [PMID: 1712992] - Z Cai, H M Mehendale. Hepatotoxicity and lethality of halomethanes in Mongolian gerbils pretreated with chlordecone, phenobarbital or mirex.
Archives of toxicology.
1991; 65(3):204-12. doi:
10.1007/bf02307310
. [PMID: 1711308] - P R Kodavanti, U P Kodavanti, H M Mehendale. Altered hepatic energy status in chlordecone (Kepone)-potentiated CCl4 hepatotoxicity.
Biochemical pharmacology.
1990 Aug; 40(4):859-66. doi:
10.1016/0006-2952(90)90327-h
. [PMID: 1696822] - Z W Cai, H M Mehendale. Lethal effects of CCl4 and its metabolism by Mongolian gerbils pretreated with chlordecone, phenobarbital, or mirex.
Toxicology and applied pharmacology.
1990 Jul; 104(3):511-20. doi:
10.1016/0041-008x(90)90173-r
. [PMID: 1696756] - S Teo, M Vore. Mirex exposure inhibits the uptake of estradiol-17 beta(beta-D-glucuronide), taurocholate, and L-alanine into isolated rat hepatocytes.
Toxicology and applied pharmacology.
1990 Jul; 104(3):411-20. doi:
10.1016/0041-008x(90)90163-o
. [PMID: 1696754] - H M Mehendale, K R Purushotham, V G Lockard. The time course of liver injury and [3H]thymidine incorporation in chlordecone-potentiated CHCl3 hepatotoxicity.
Experimental and molecular pathology.
1989 Aug; 51(1):31-47. doi:
10.1016/0014-4800(89)90005-1
. [PMID: 2475365] - H M Mehendale, J S Klingensmith. In vivo metabolism of CCl4 by rats pretreated with chlordecone, mirex, or phenobarbital.
Toxicology and applied pharmacology.
1988 Apr; 93(2):247-56. doi:
10.1016/0041-008x(88)90124-x
. [PMID: 2451866] - L D Brown, J D Yarbrough. Mirex uptake and tissue disposition in intact and adrenalectomized rats.
Toxicology and applied pharmacology.
1988 Mar; 92(3):343-50. doi:
10.1016/0041-008x(88)90174-3
. [PMID: 3353985] - L D Brown, D E Wilson, J D Yarbrough. Alterations in the hepatic glucocorticoid response to mirex treatment.
Toxicology and applied pharmacology.
1988 Feb; 92(2):203-13. doi:
10.1016/0041-008x(88)90380-8
. [PMID: 2893471] - K R Purushotham, V G Lockard, H M Mehendale. Amplification of chloroform hepatotoxicity and lethality by dietary chlordecone (kepone) in mice.
Toxicologic pathology.
1988; 16(1):27-34. doi:
10.1177/019262338801600104
. [PMID: 2453913] - L Jovanovich, S Levin, M A Khan. Significance of mirex-caused hypoglycemia and hyperlipidemia in rats.
Journal of biochemical toxicology.
1987 Sep; 2(?):203-13. doi:
10.1002/jbt.2570020305
. [PMID: 3508472] - G L Plaa, G Caillé, M Vézina, M Iijima, M G Côté. Chloroform interaction with chlordecone and mirex: correlation between biochemical and histological indices of toxicity and quantitative tissue levels.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1987 Aug; 9(2):198-207. doi:
10.1016/0272-0590(87)90043-1
. [PMID: 2443411] - H Komulainen, S C Bondy. Modulation of levels of free calcium within synaptosomes by organochlorine insecticides.
The Journal of pharmacology and experimental therapeutics.
1987 May; 241(2):575-81. doi:
NULL
. [PMID: 2437290] - P E Thomas, S Bandiera, S L Maines, D E Ryan, W Levin. Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes.
Biochemistry.
1987 Apr; 26(8):2280-9. doi:
10.1021/bi00382a031
. [PMID: 3113478] - A N Bell, H M Mehendale. Comparative changes in hepatic DNA, RNA, protein, lipid, and glycogen induced by a subtoxic dose of CCl4 in chlordecone, mirex, and phenobarbital pretreated rats.
Toxicology letters.
1987 Feb; 35(2-3):191-200. doi:
10.1016/0378-4274(87)90206-2
. [PMID: 2435023] - L A Hewitt, P Ayotte, G L Plaa. Modifications in rat hepatobiliary function following treatment with acetone, 2-butanone, 2-hexanone, mirex, or chlordecone and subsequently exposed to chloroform.
Toxicology and applied pharmacology.
1986 May; 83(3):465-73. doi:
10.1016/0041-008x(86)90229-2
. [PMID: 2422788] - D P Rosenbaum, A K Charles. In vitro binding of mirex by mouse hepatocytes.
Journal of toxicology and environmental health.
1986; 17(4):385-93. doi:
10.1080/15287398609530833
. [PMID: 3959119] - A N Bell, H M Mehendale. The effect of dietary exposure to a mirex plus chlordecone combination on CCl4 hepatotoxicity.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1985 Aug; 5(4):679-87. doi:
10.1016/0272-0590(85)90192-7
. [PMID: 2412926] - M G Ervin, J D Yarbrough. Mirex-induced liver enlargement in rats is dependent upon an intact pituitary-adrenalcortical axis.
Life sciences.
1985 Jan; 36(2):139-45. doi:
10.1016/0024-3205(85)90092-x
. [PMID: 2981382] - A K Charles, D P Rosenbaum, L Ashok, R Abraham. Uptake and disposition of mirex in hepatocytes and subcellular fractions in CD1 mouse liver.
Journal of toxicology and environmental health.
1985; 15(3-4):395-403. doi:
10.1080/15287398509530667
. [PMID: 4032488] - F W Kutz, S C Strassman, C R Stroup, J S Carra, C C Leininger, D L Watts, C M Sparacino. The human body burden of mirex in the southeastern United States.
Journal of toxicology and environmental health.
1985; 15(3-4):385-94. doi:
10.1080/15287398509530666
. [PMID: 4032487] - L R Curtis, D Hoyt. Impaired biliary excretion of taurocholate associated with increased biliary tree permeability in mirex- or chlordecone-pretreated rats.
The Journal of pharmacology and experimental therapeutics.
1984 Dec; 231(3):495-501. doi:
. [PMID: 6209385]
- J M Rogers, L Morelli, C T Grabowski. Plasma glucose and protein concentrations in rat fetuses and neonates exposed to cataractogenic doses of mirex.
Environmental research.
1984 Jun; 34(1):155-61. doi:
10.1016/0013-9351(84)90084-7
. [PMID: 6723604] - K Rozman, T Rozman, G S Smith. Liquid paraffins in feed enhance fecal excretion of mirex and DDE from body stores of lactating goats and cows.
Bulletin of environmental contamination and toxicology.
1984 Jan; 32(1):27-36. doi:
10.1007/bf01607461
. [PMID: 6697018] - J S Klingensmith, H M Mehendale. Destruction of hepatic mixed-function oxygenase parameters by CCl4 in rats following acute treatment with chlordecone, Mirex, and phenobarbital.
Life sciences.
1983 Dec; 33(23):2339-48. doi:
10.1016/0024-3205(83)90268-0
. [PMID: 6196592] - L A Hewitt, W R Hewitt, G L Plaa. Fractional hepatic localization of 14CHCl3 in mice and rats treated with chlordecone or mirex.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1983 Nov; 3(6):489-95. doi:
10.1016/s0272-0590(83)80093-1
. [PMID: 6198233] - J S Klingensmith, V Lockard, H M Mehendale. Acute hepatotoxicity and lethality of CCl4 in chlordecone-pretreated rats.
Experimental and molecular pathology.
1983 Aug; 39(1):1-10. doi:
10.1016/0014-4800(83)90036-9
. [PMID: 6192011] - J S Klingensmith, H M Mehendale. Hepatic microsomal metabolism of CCL4 after pretreatment with chlordecone, mirex, or phenobarbital in male rats.
Drug metabolism and disposition: the biological fate of chemicals.
1983 Jul; 11(4):329-34. doi:
. [PMID: 6193935]
- K Fujimori, H Benet, H M Mehendale, I K Ho. Comparison of brain discrete area distributions of chlordecone and mirex in the mouse.
Neurotoxicology.
1982 Oct; 3(2):125-29. doi:
NULL
. [PMID: 6186957] - J E Chambers, R S Case, E G Alley, J D Yarbrough. Short-term fate of mirex and 2,8-dihydromirex in rats.
Journal of agricultural and food chemistry.
1982 Sep; 30(5):878-82. doi:
10.1021/jf00113a020
. [PMID: 7142591] - A Singh, V E Valli, L Ritter, D C Villeneuve. Ultrastructural alterations in the liver of rats fed photomirex (8-monohydromirex).
Pathology.
1981 Jul; 13(3):487-96. doi:
10.3109/00313028109059066
. [PMID: 7301416] - C T Grabowski. Plasma proteins and colloid osmotic pressure of blood of rat fetuses prenatally exposed to Mirex.
Journal of toxicology and environmental health.
1981 May; 7(5):705-14. doi:
10.1080/15287398109530013
. [PMID: 7265304] - H M Mehendale. Onset and recovery from chlordecone- and mirex-induced hepatobiliary dysfunction.
Toxicology and applied pharmacology.
1981 Mar; 58(1):132-9. doi:
10.1016/0041-008x(81)90123-x
. [PMID: 6165098] - I Chu, D C Villeneuve, B L MacDonald, V E Secours, V E Valli. Reversibility of the toxicological changes induced by photomirex and mirex.
Toxicology.
1981; 21(3):235-50. doi:
10.1016/0300-483x(81)90159-1
. [PMID: 7292508] - T Rozman, K Rozman, J Williams, H Greim. Enhanced fecal excretion of mirex in rhesus monkeys by 5\% mineral oil in the diet.
Drug and chemical toxicology.
1981; 4(3):251-62. doi:
10.3109/01480548109018132
. [PMID: 7338205] - K Fujimori, I K Ho, H M Mehendale. Assessment of photomirex toxicity in the mouse.
Journal of toxicology and environmental health.
1980 Jul; 6(4):869-76. doi:
10.1080/15287398009529905
. [PMID: 7420486] - I Chu, D C Villeneuve, G C Becking, A Viau. Tissue distribution and elimination of 2,8-dihydromirex in the rat.
Journal of toxicology and environmental health.
1980 Jul; 6(4):713-21. doi:
10.1080/15287398009529890
. [PMID: 7420475] - F A Ahrens, D C Dyer, W E Lloyd. Mirex kinetics in chickens.
Journal of toxicology and environmental health.
1980 Jul; 6(4):835-42. doi:
10.1080/15287398009529901
. [PMID: 7420484] - I Chu, D C Villeneuve, G C Becking, F Iverson, L Ritter, V E Valli, L M Reynolds. Short-term study of the combined effects of mirex, photomirex, and kepone with halogenated biphenyls in rats.
Journal of toxicology and environmental health.
1980 Mar; 6(2):421-32. doi:
10.1080/15287398009529861
. [PMID: 6156243] - A Sundaram, D C Villeneuve, I Chu, V Secours, G C Becking. Subchronic toxicity of photomirex in the female rat: results of 28- and 90-day feeding studies.
Drug and chemical toxicology.
1980; 3(1):105-34. doi:
10.3109/01480548009017837
. [PMID: 6156066] - V B Stein, K A Pittman. Gas-liquid chromatographic determination of mirex in plasma, liver and fat from mice and monkeys.
Bulletin of environmental contamination and toxicology.
1979 Oct; 23(3):300-5. doi:
10.1007/bf01769960
. [PMID: 117856] - M K Samson, R L Stephens, S Rivkin, M Opipari, T Maloney, C W Groppe, R Fisher. Vinblastine, bleomycin, and cis-dichlorodiammineplatinum(II) in disseminated testicular cancer: preliminary report of a Southwest Oncology Group Study.
Cancer treatment reports.
1979 Sep; 63(9-10):1663-7. doi:
. [PMID: 91435]
- W R Hewitt, H Miyajima, M G Côté, G L Plaa. Acute alteration of chloroform-induced hepato- and nephrotoxicity by Mirex and Kepone.
Toxicology and applied pharmacology.
1979 May; 48(3):509-27. doi:
10.1016/0041-008x(79)90434-4
. [PMID: 89712] - D P Morgan, S H Sandifier, H L Hetzler, E F Slach, C D Brady, J Colcolough. Test for in vivo conversion of mirex to kepone.
Bulletin of environmental contamination and toxicology.
1979 May; 22(1-2):238-44. doi:
10.1007/bf02026936
. [PMID: 88976] - D C Villeneuve, V E Valli, I Chu, V Secours, L Ritter, G C Becking. Ninety-day toxicity of photomirex in the male rat.
Toxicology.
1979 Mar; 12(3):235-50. doi:
10.1016/0300-483x(79)90069-6
. [PMID: 494305] - M W Kendall. Light and electron microscopic observations of the acute sublethal hepatotoxic effects of Mirex in the rat.
Archives of environmental contamination and toxicology.
1979; 8(1):25-41. doi:
10.1007/bf01055138
. [PMID: 533307] - I Chu, D C Villeneuve, V Secours, G C Becking, A Viau, F Benoit. The absorption, distribution and excretion of photomirex in the rat.
Drug metabolism and disposition: the biological fate of chemicals.
1979 Jan; 7(1):24-7. doi:
NULL
. [PMID: 35322] - D C Villeneuve, K S Khera, G Trivett, G Felsky, R J Norstrom, I Chu. Photomirex: a teratogenicity and tissue distribution study in the rabbit.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
1979; 14(2):171-80. doi:
10.1080/03601237909372120
. [PMID: 438460] - J F Leatherland, R A Sonstegard, M V Holdrinet. Effect of dietary Mirex and PCB's on hepatosomatic index, liver lipid, carcass lipid and PCB and Mirex bioaccumulation in yearling coho salmon, Oncorhynchus kisutch.
Comparative biochemistry and physiology. C: Comparative pharmacology.
1979; 63C(2):243-6. doi:
10.1016/0306-4492(79)90068-6
. [PMID: 40732] - M D Reuber. Acute and chronic renal and hepatic disease in rats fed Mirex.
Journal of the National Cancer Institute.
1977 Oct; 59(4):1051-3. doi:
10.1093/jnci/59.4.1051
. [PMID: 903988]