Daidzin (BioDeep_00000002593)

 

Secondary id: BioDeep_00000270069

natural product human metabolite PANOMIX_OTCML-2023 Antitumor activity BioNovoGene_Lab2019


代谢物信息卡片


3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

化学式: C21H20O9 (416.1107)
中文名称: 黄豆甙, 大豆甙, 黄豆苷, 豆苷, 大豆苷, 大豆苷(大豆黄酮-7-O-葡萄糖苷), 大豆苷、大豆黄酮-7-O-葡萄糖苷
谱图信息: 最多检出来源 Homo sapiens(otcml) 7.92%

分子结构信息

SMILES: c1(ccc2c(c1)occ(c2=O)c1ccc(cc1)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
InChI: InChI=1/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1

描述信息

Daidzein 7-O-beta-D-glucoside is a glycosyloxyisoflavone that is daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic). It has a role as a plant metabolite. It is a hydroxyisoflavone, a monosaccharide derivative and a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a daidzein.
Daidzin is a natural product found in Thermopsis lanceolata, Thermopsis macrophylla, and other organisms with data available.
See also: Astragalus propinquus root (part of).
Daidzin is found in miso. Daidzin is isolated from soya bean (Glycine max) and soya bean meal, kudzu root (Pueraria lobata), alfalfa (Medicago sativa) and other Leguminosae.Daidzin is a cancer preventive and an alcohol dependency treatment (antidipsotropic) in animal models. Daidzin is a natural organic compound in the class of phytochemicals known as isoflavones. Daidzin can be found in Japanese plant Kudzu (Pueraria lobata, Fabaceae) and from soybean leaves
A glycosyloxyisoflavone that is daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic).
Isolated from soya bean (Glycine max) and soya bean meal, kudzu root (Pueraria lobata), alfalfa (Medicago sativa) and other Leguminosae
D002491 - Central Nervous System Agents > D000427 - Alcohol Deterrents
D004791 - Enzyme Inhibitors
Acquisition and generation of the data is financially supported in part by CREST/JST.
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities.
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption[1].
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities.

同义名列表

51 个代谢物同义名

3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; 3-(4-hydroxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one; 3-(4-hydroxyphenyl)-7-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one; 3-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one; 3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one; 7-(beta-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl beta-D-glucopyranoside; 7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-chromen-4-one; 3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside; Daidzin, United States Pharmacopeia (USP) Reference Standard; Daidzin, primary pharmaceutical reference standard; 4,7-DIHYDROXYISOFLAVONE; 7-O-B-D-GLUCOPYRANOSIDE; 4,7-Dihydroxyisoflavone 7-O-b-D-glucopyranoside; DAIDZIN (CONSTITUENT OF SOY ISOFLAVONES) [DSC]; 4-18-00-01808 (Beilstein Handbook Reference); DAIDZIN (CONSTITUENT OF ASTRAGALUS) [DSC]; DAIDZIN (CONSTITUENT OF SOY ISOFLAVONES); 7,4-Dihydroxyisoflavone 7-glucoside; DAIDZIN (CONSTITUENT OF ASTRAGALUS); Daidzein 7-O-beta-D-glucopyranoside; Daidzein 7-O-|A-D-glucopyranoside; 7-O-glucosyl-4-hydroxyisoflavone; DAIDZEIN 7-O-.BETA.-D-GLUCOSIDE; daidzein 7-O-beta-D-glucoside; Daidzin, analytical standard; KYQZWONCHDNPDP-QNDFHXLGSA-N; 7-O-beta-D-glucopyranoside; Daidzein 7-O-β-D-glucoside; Daidzein 7-O-b-D-glucoside; Daidzin, >=95.0\\% (HPLC); daidzein-7-o-glucoside; Daidzein 7-O-glucoside; DAIDZEIN DAIDZIN [MI]; Daidzein 7-glucoside; Daidzein-7-glucoside; DAIDZEIN DAIDZIN; DAIDZIN [USP-RS]; DAIDZIN (USP-RS); UNII-4R2X91A5M5; MEGxp0_000530; ACon1_002092; Daidzoside; 4R2X91A5M5; Daidzin; Dadzin; 2vle; DZN; Daidzein-7-O-β-D-glucopyranoside; Daidzein O-hexoside; Daidzin; NPI-031D



数据库引用编号

50 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

232 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 BCL2, CASP3, CAT, JAK2, MAPK14, MAPK8, MTOR, NFE2L2, PIK3CA, PTGS2, RB1, STAT3, TYR
Peripheral membrane protein 3 JAK2, MTOR, PTGS2
Endoplasmic reticulum membrane 4 BCL2, HMOX1, MTOR, PTGS2
Nucleus 10 BCL2, CASP3, HMOX1, JAK2, MAPK14, MAPK8, MTOR, NFE2L2, RB1, STAT3
cytosol 13 BCL2, CASP3, CAT, GPT, HMOX1, JAK2, MAPK14, MAPK8, MTOR, NFE2L2, PIK3CA, RB1, STAT3
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 1 NFE2L2
nucleoplasm 9 CASP3, HMOX1, JAK2, MAPK14, MAPK8, MTOR, NFE2L2, RB1, STAT3
RNA polymerase II transcription regulator complex 2 NFE2L2, STAT3
Cell membrane 1 TNF
Cytoplasmic side 2 HMOX1, MTOR
lamellipodium 1 PIK3CA
Golgi apparatus membrane 1 MTOR
Synapse 1 MAPK8
cell surface 1 TNF
glutamatergic synapse 3 CASP3, JAK2, MAPK14
Golgi apparatus 1 NFE2L2
Golgi membrane 2 INS, MTOR
lysosomal membrane 2 GAA, MTOR
neuronal cell body 2 CASP3, TNF
postsynapse 1 JAK2
Cytoplasm, cytosol 1 NFE2L2
Lysosome 3 GAA, MTOR, TYR
plasma membrane 6 GAA, JAK2, NFE2L2, PIK3CA, STAT3, TNF
Membrane 6 BCL2, CAT, GAA, HMOX1, JAK2, MTOR
axon 1 MAPK8
caveola 2 JAK2, PTGS2
extracellular exosome 4 ALDH2, CAT, GAA, GPT
Lysosome membrane 2 GAA, MTOR
endoplasmic reticulum 3 BCL2, HMOX1, PTGS2
extracellular space 4 HMOX1, IL6, INS, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 3 HMOX1, PIK3CA, TYR
intercalated disc 1 PIK3CA
mitochondrion 4 ALDH2, BCL2, CAT, MAPK14
protein-containing complex 3 BCL2, CAT, PTGS2
intracellular membrane-bounded organelle 3 CAT, GAA, TYR
Microsome membrane 2 MTOR, PTGS2
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 TYR
Secreted 3 GAA, IL6, INS
extracellular region 6 CAT, GAA, IL6, INS, MAPK14, TNF
cytoplasmic side of plasma membrane 1 JAK2
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 3 BCL2, HMOX1, MTOR
Mitochondrion matrix 1 ALDH2
mitochondrial matrix 2 ALDH2, CAT
transcription regulator complex 1 STAT3
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 JAK2, TNF
pore complex 1 BCL2
focal adhesion 2 CAT, JAK2
spindle 1 RB1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 MTOR
PML body 2 MTOR, RB1
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
chromatin 3 NFE2L2, RB1, STAT3
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
cytoskeleton 1 JAK2
spindle pole 1 MAPK14
nuclear envelope 1 MTOR
Endomembrane system 2 JAK2, MTOR
endosome lumen 2 INS, JAK2
tertiary granule membrane 1 GAA
Melanosome 1 TYR
euchromatin 1 JAK2
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 3 CAT, INS, MAPK14
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
SWI/SNF complex 1 RB1
Single-pass type IV membrane protein 1 HMOX1
extrinsic component of cytoplasmic side of plasma membrane 1 JAK2
protein-DNA complex 1 NFE2L2
ficolin-1-rich granule membrane 1 GAA
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, phagosome 1 MTOR
extrinsic component of plasma membrane 1 JAK2
granulocyte macrophage colony-stimulating factor receptor complex 1 JAK2
interleukin-12 receptor complex 1 JAK2
interleukin-23 receptor complex 1 JAK2
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
chromatin lock complex 1 RB1
Rb-E2F complex 1 RB1
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Shuai Yuan, Ibrahim Abdel Aziz Ibrahim, Ruimin Ren. Anti-urolithiatic Activity of Daidzin in Ethylene Glycol-Induced Urolithiasis in Rats. Applied biochemistry and biotechnology. 2023 Feb; 195(2):905-918. doi: 10.1007/s12010-022-04124-y. [PMID: 36227501]
  • Quanli Liu, Yi Liu, Gang Li, Otto Savolainen, Yun Chen, Jens Nielsen. De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories. Nature communications. 2021 10; 12(1):6085. doi: 10.1038/s41467-021-26361-1. [PMID: 34667183]
  • Dan Gao, Jin Hyeok Kim, Cheong Taek Kim, Won Seok Jeong, Hyung Min Kim, Jaehoon Sim, Jong Seong Kang. Evaluation of Anti-Melanogenesis Activity of Enriched Pueraria lobata Stem Extracts and Characterization of Its Phytochemical Components Using HPLC-PDA-ESI-MS/MS. International journal of molecular sciences. 2021 Jul; 22(15):. doi: 10.3390/ijms22158105. [PMID: 34360871]
  • Miwako Toyofuku, Fuki Okutani, Masaru Nakayasu, Shoichiro Hamamoto, Hisabumi Takase, Kazufumi Yazaki, Akifumi Sugiyama. Enhancement of developmentally regulated daidzein secretion from soybean roots in field conditions as compared with hydroponic culture. Bioscience, biotechnology, and biochemistry. 2021 Apr; 85(5):1165-1169. doi: 10.1093/bbb/zbab017. [PMID: 33784734]
  • Su-Jin Ahn, Hyung Joo Kim, Ayoung Lee, Seung-Sik Min, Sangwhan In, Eunmi Kim. Determination of 12 herbal compounds for estimating the presence of Angelica Gigas Root, Cornus Fruit, Licorice Root, Pueraria Root, and Schisandra Fruit in foods by LC-MS/MS. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2020 Sep; 37(9):1437-1448. doi: 10.1080/19440049.2020.1778187. [PMID: 32530783]
  • Zartashia Kazmi, Sara Zeeshan, Adnan Khan, Sumra Malik, Adeeb Shehzad, Eun Kyoung Seo, Salman Khan. Anti-epileptic activity of daidzin in PTZ-induced mice model by targeting oxidative stress and BDNF/VEGF signaling. Neurotoxicology. 2020 07; 79(?):150-163. doi: 10.1016/j.neuro.2020.05.005. [PMID: 32450180]
  • You Jin Lim, Ho Young Jeong, Chan Saem Gil, Soon-Jae Kwon, Jong Kuk Na, Chanhui Lee, Seok Hyun Eom. Isoflavone accumulation and the metabolic gene expression in response to persistent UV-B irradiation in soybean sprouts. Food chemistry. 2020 Jan; 303(?):125376. doi: 10.1016/j.foodchem.2019.125376. [PMID: 31442900]
  • Yingjie Sun, Hongmin Zhang, Ming Cheng, Shijie Cao, Miao Qiao, Boli Zhang, Liqin Ding, Feng Qiu. New hepatoprotective isoflavone glucosides from Pueraria lobata (Willd.) Ohwi. Natural product research. 2019 Dec; 33(24):3485-3492. doi: 10.1080/14786419.2018.1484461. [PMID: 29968479]
  • Kung-Chieh Wu, Wei-Yu Lin, Yi-Ting Sung, Wei-Yi Wu, Yu-Hsiuan Cheng, Tung-Sheng Chen, Bing-Juin Chiang, Chiang-Ting Chien. Glycine tomentella hayata extract and its ingredient daidzin ameliorate cyclophosphamide-induced hemorrhagic cystitis and oxidative stress through the action of antioxidation, anti-fibrosis, and anti-inflammation. The Chinese journal of physiology. 2019 Sep; 62(5):188-195. doi: 10.4103/cjp.cjp_60_19. [PMID: 31670282]
  • Juping Zhang, Qianxiang Guo, Meijin Wei, Junqi Bai, Juan Huang, Yuhong Liu, Ziren Su, Xiaohui Qiu. Metabolite Identification and Pharmacokinetic Profiling of Isoflavones from Black Soybean in Rats Using Ultrahigh-Performance Liquid Chromatography with Linear-Ion-Trap-Orbitrap and Triple-Quadrupole Tandem Mass Spectrometry. Journal of agricultural and food chemistry. 2018 Dec; 66(49):12941-12952. doi: 10.1021/acs.jafc.8b04852. [PMID: 30444115]
  • Kung-Chieh Wu, Bing-Juin Chiang, Wen-Hsin Tsai, Shiu-Dong Chung, Chiang-Ting Chien. I-Tiao-Gung extract through its active component daidzin improves cyclophosphamide-induced bladder dysfunction in rat model. Neurourology and urodynamics. 2018 11; 37(8):2560-2570. doi: 10.1002/nau.23815. [PMID: 30252154]
  • Paulo Luiz DA Silva, Gláucia Cordeiro, Carolina R DA Silva, Rafael A Barros, Camila R DA Silva, José C Zanuncio, Wellington G Campos, Maria G A Oliveira. Does mechanical damage on soybean induces the production of flavonoids?. Anais da Academia Brasileira de Ciencias. 2018 Oct; 90(4):3415-3422. doi: 10.1590/0001-3765201820170850. [PMID: 30365711]
  • Feng Qiu, Linyi Shi, Siqi Wang, Sha Wu, Manyuan Wang. Simultaneous high-performance liquid chromatography with diode array detection and time-of-flight mass spectrometric confirmation of the ten bioactive compounds in Semen Sojae Preparatum. Journal of separation science. 2018 Sep; 41(17):3360-3371. doi: 10.1002/jssc.201800504. [PMID: 30016573]
  • Charles C Lee, Stéphanie Dudonné, Jong Hun Kim, Ji Seung Kim, Pascal Dubé, Jong-Eun Kim, Yves Desjardins, Jung Han Yoon Park, Ki Won Lee, Chang Yong Lee. A major daidzin metabolite 7,8,4'-trihydroxyisoflavone found in the plasma of soybean extract-fed rats attenuates monocyte-endothelial cell adhesion. Food chemistry. 2018 Feb; 240(?):607-614. doi: 10.1016/j.foodchem.2017.08.002. [PMID: 28946319]
  • Mei-Yan Yang, Ya-Bin Wang, Bo Han, Bo Yang, Yu-Wei Qiang, Yan Zhang, Zhao Wang, Xu Huang, Jie Liu, Yun-Dai Chen, Jun Ren, Feng Cao, Yong Xu. Activation of aldehyde dehydrogenase 2 slows down the progression of atherosclerosis via attenuation of ER stress and apoptosis in smooth muscle cells. Acta pharmacologica Sinica. 2018 Jan; 39(1):48-58. doi: 10.1038/aps.2017.81. [PMID: 28858301]
  • Yunjeong Kim, Ji-Young Jeon, Eun-Young Kim, Cheol-Hee Lim, Hwan Bong Jang, Min-Gul Kim. Pharmacokinetics and Safety of DW1029M, a Botanical Drug for the Treatment of Diabetic Nephropathy, Following Single Doses in Healthy Subjects. Clinical pharmacology in drug development. 2017 Sep; 6(5):499-507. doi: 10.1002/cpdd.343. [PMID: 28301092]
  • Xiao-Ling Wang, Fu-Rong Jiao, Meng Yu, Li-Bin Lin, Jian Xiao, Qiang Zhang, Le Wang, Dong-Zhu Duan, Gang Xie. Constituents with potent α-glucosidase inhibitory activity from Pueraria lobata (Willd.) ohwi. Bioorganic & medicinal chemistry letters. 2017 05; 27(9):1993-1998. doi: 10.1016/j.bmcl.2017.03.013. [PMID: 28343876]
  • Alírica I Suárez, Zaw Min Thu, Jorge Ramírez, Diana León, Luis Cartuche, Chabaco Armijos, Geovanni Vidari. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Natural product communications. 2017 Apr; 12(4):533-535. doi: . [PMID: 30520590]
  • Hee Rae Kang, Dahae Lee, René Benndorf, Won Hee Jung, Christine Beemelmanns, Ki Sung Kang, Ki Hyun Kim. Termisoflavones A-C, Isoflavonoid Glycosides from Termite-Associated Streptomyces sp. RB1. Journal of natural products. 2016 Dec; 79(12):3072-3078. doi: 10.1021/acs.jnatprod.6b00738. [PMID: 28006913]
  • José P da Graça, Tatiana E Ueda, Tatiani Janegitz, Simone S Vieira, Mariana C Salvador, Maria C N de Oliveira, Sonia M Zingaretti, Stephen J Powers, John A Pickett, Michael A Birkett, Clara B Hoffmann-Campo. The natural plant stress elicitor cis-jasmone causes cultivar-dependent reduction in growth of the stink bug, Euschistus heros and associated changes in flavonoid concentrations in soybean, Glycine max. Phytochemistry. 2016 Nov; 131(?):84-91. doi: 10.1016/j.phytochem.2016.08.013. [PMID: 27659594]
  • Heung Joo Yuk, Yeong Hun Song, Marcus J Curtis-Long, Dae Wook Kim, Su Gyeong Woo, Yong Bok Lee, Zia Uddin, Cha Young Kim, Ki Hun Park. Ethylene Induced a High Accumulation of Dietary Isoflavones and Expression of Isoflavonoid Biosynthetic Genes in Soybean (Glycine max) Leaves. Journal of agricultural and food chemistry. 2016 Oct; 64(39):7315-7324. doi: 10.1021/acs.jafc.6b02543. [PMID: 27626287]
  • Mohd Zaheer, Vudem Dashavantha Reddy, Charu Chandra Giri. Enhanced daidzin production from jasmonic and acetyl salicylic acid elicited hairy root cultures of Psoralea corylifolia L. (Fabaceae). Natural product research. 2016 Jul; 30(13):1542-7. doi: 10.1080/14786419.2015.1054823. [PMID: 26156378]
  • Bili Su, Yongjun Kan, Jianwei Xie, Juan Hu, Wensheng Pang. Relevance of the Pharmacokinetic and Pharmacodynamic Profiles of Puerariae lobatae Radix to Aggregation of Multi-Component Molecules in Aqueous Decoctions. Molecules (Basel, Switzerland). 2016 Jun; 21(7):. doi: 10.3390/molecules21070845. [PMID: 27367654]
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  • Kailee A Johnson, Sravan Vemuri, Sameerh Alsahafi, Rudy Castillo, Venugopalan Cheriyath. Glycone-rich Soy Isoflavone Extracts Promote Estrogen Receptor Positive Breast Cancer Cell Growth. Nutrition and cancer. 2016 May; 68(4):622-33. doi: 10.1080/01635581.2016.1154578. [PMID: 27043076]
  • Yan Zhang, Sam K C Chang. Isoflavone Profiles and Kinetic Changes during Ultra-High Temperature Processing of Soymilk. Journal of food science. 2016 Mar; 81(3):C593-9. doi: 10.1111/1750-3841.13236. [PMID: 26814612]
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  • Huihua Qu, Baoping Qu, Xueqian Wang, Yue Zhang, Jinjun Cheng, Wenhao Zeng, Shuchen Liu, Qingguo Wang, Yan Zhao. Rapid, sensitive separation of the three main isoflavones in soybean using immunoaffinity chromatography. Journal of separation science. 2016 Mar; 39(6):1195-201. doi: 10.1002/jssc.201501052. [PMID: 26813984]
  • Gorawit Yusakul, Seiichi Sakamoto, Thaweesak Juengwatanatrakul, Waraporn Putalun, Hiroyuki Tanaka, Satoshi Morimoto. Preparation and application of a monoclonal antibody against the isoflavone glycoside daidzin using a mannich reaction-derived hapten conjugate. Phytochemical analysis : PCA. 2016 Jan; 27(1):81-8. doi: 10.1002/pca.2604. [PMID: 26689919]
  • Shuai Wu, Wei Xu, Fu-Rong Wang, Xiu-Wei Yang. Study of the Biotransformation of Tongmai Formula by Human Intestinal Flora and Its Intestinal Permeability across the Caco-2 Cell Monolayer. Molecules (Basel, Switzerland). 2015 Oct; 20(10):18704-16. doi: 10.3390/molecules201018704. [PMID: 26501241]
  • Yeming Chen, Sam K C Chang. Macronutrients, Phytochemicals, and Antioxidant Activity of Soybean Sprout Germinated with or without Light Exposure. Journal of food science. 2015 Jun; 80(6):S1391-8. doi: 10.1111/1750-3841.12868. [PMID: 25916398]
  • Xin Wang, Shutao Li, Jia Li, Changfu Li, Yansheng Zhang. De novo transcriptome sequencing in Pueraria lobata to identify putative genes involved in isoflavones biosynthesis. Plant cell reports. 2015 May; 34(5):733-43. doi: 10.1007/s00299-014-1733-1. [PMID: 25547742]
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