D-Glucuronate (BioDeep_00000001733)

 

Secondary id: BioDeep_00000003270, BioDeep_00000055253, BioDeep_00000265136, BioDeep_00000400046, BioDeep_00000859614

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


(2S,3S,4S,5R,6S)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid

化学式: C6H10O7 (194.042651)
中文名称: D-葡萄糖醛酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.01%

Reviewed

Last reviewed on 2024-08-21.

Cite this Page

D-Glucuronate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/d-glucuronate (retrieved 2024-11-25) (BioDeep RN: BioDeep_00000001733). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1(C(C(OC(C1O)O)C(=O)O)O)O
InChI: InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1

描述信息

Glucuronic acid (CAS: 6556-12-3) is a carboxylic acid that has the structure of a glucose molecule that has had its sixth carbon atom (of six total) oxidized. The salts of glucuronic acid are known as glucuronates. Glucuronic acid is highly soluble in water. In humans, glucuronic acid is often linked to toxic or poisonous substances to allow for subsequent elimination, and to hormones to allow for easier transport. These linkages involve O-glycosidic bonds. The process is known as glucuronidation, and the resulting substances are known as glucuronides (or glucuronosides). Glucuronidation uses UDP-glucuronic acid (glucuronic acid linked via a glycosidic bond to uridine diphosphate) as an intermediate. UDP-glucuronic acid is formed in the liver of all animals.

D-Glucuronic acid is an important intermediate isolated from many gums. D-Glucuronic acid and its derivative glucuronolactone are as a liver antidote in the prophylaxis of human health. D-Glucuronic acid has an anti-inflammatory effect for the skin[1].
D-Glucuronic acid is an important intermediate isolated from many gums. D-Glucuronic acid and its derivative glucuronolactone are as a liver antidote in the prophylaxis of human health. D-Glucuronic acid has an anti-inflammatory effect for the skin[1].

同义名列表

28 个代谢物同义名

(2S,3S,4S,5R,6S)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid; α-δ-glucopyranuronic acid; alpha-D-Glucopyranosyluronic acid; α-D-glucopyranuronic acid; α-δ-glucuronic acid; α-D-Glucopyranosyluronic acid; alpha-D-Glucopyranuronic acid; δ-(+)-glucuronic acid; α-D-glucuronic acid; α-D-Glucopyranuronic acid; alpha-D-Glucuronic acid; D-Glucopyranuronic acid; δ-(+)-glucuronate; beta-D-glucuronic acid; D-(+)-Glucuronic acid; δ-glucuronate; Glucosiduronic acid; D-Glucuronic acid; D-(+)-Glucuronate; Glucosiduronate; Glucuronic acid; D-Glucuronate; Glucuronate; GlcAalpha; GlcAa; GCU; Glucuronic acid; D-Glucuronate



数据库引用编号

39 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(7)

PlantCyc(0)

代谢反应

458 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(58)

WikiPathways(0)

Plant Reactome(0)

INOH(1)

PlantCyc(369)

COVID-19 Disease Map(0)

PathBank(30)

PharmGKB(0)

28 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Guofu Yan, Jiawei Zhou, Xueqing Cui, Ming Liu, Shiyang Bai, Jihong Sun, Jie Tang, Kaikai Li, Sa Liu. Physicochemical properties and fractal characterizations of the functionalized porous clinoptilolites for controlling alginate delivery in growing cauliflower and leaf mustard. Plant physiology and biochemistry : PPB. 2024 Jun; 211(?):108694. doi: 10.1016/j.plaphy.2024.108694. [PMID: 38714131]
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  • Zhimin Li, Runping Chen, Yufang Wen, Hanxiang Liu, Yangyang Chen, Xiaoyu Wu, Youxin Yang, Xinru Wu, Yong Zhou, Jianping Liu. Comprehensive analysis of the UDP-glucuronate decarboxylase (UXS) gene family in tobacco and functional characterization of NtUXS16 in Golgi apparatus in Arabidopsis. BMC plant biology. 2023 Nov; 23(1):551. doi: 10.1186/s12870-023-04575-3. [PMID: 37936064]
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  • Nan Ruan, Zhengjun Dang, Meihan Wang, Liyu Cao, Ye Wang, Sitong Liu, Yijun Tang, Yuwei Huang, Qun Zhang, Quan Xu, Wenfu Chen, Fengcheng Li. FRAGILE CULM 18 encodes a UDP-glucuronic acid decarboxylase required for xylan biosynthesis and plant growth in rice. Journal of experimental botany. 2022 04; 73(8):2320-2335. doi: 10.1093/jxb/erac036. [PMID: 35104839]
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  • Duangjai Tungmunnithum, Samantha Drouet, Christophe Hano. Flavonoids from Sacred Lotus Stamen Extract Slows Chronological Aging in Yeast Model by Reducing Oxidative Stress and Maintaining Cellular Metabolism. Cells. 2022 02; 11(4):. doi: 10.3390/cells11040599. [PMID: 35203251]
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  • Ping Zhou, Jing Zhang, Yudi Xu, Peng Zhang, Yongqing Xiao, Ying Liu. Simultaneous quantification of anthraquinone glycosides, aglycones, and glucuronic acid metabolites in rat plasma and tissues after oral administration of raw and steamed rhubarb in blood stasis rats by UHPLC-MS/MS. Journal of separation science. 2022 Jan; 45(2):529-541. doi: 10.1002/jssc.202100623. [PMID: 34784448]
  • Wenxiang Xiao, Jing Liu, Yinan Xiong, Yaoxin Li, Hua Li. Fluorescent sensing of free bilirubin at nanomolar level using a Langmuir-Blodgett film of glucuronic acid-functionalized gold nanoclusters. Analytical and bioanalytical chemistry. 2021 Nov; 413(28):7009-7019. doi: 10.1007/s00216-021-03660-6. [PMID: 34535815]
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