Fenobucarb (BioDeep_00000009896)
Secondary id: BioDeep_00000403660
human metabolite blood metabolite
代谢物信息卡片
化学式: C12H17NO2 (207.1259)
中文名称: 丁苯威, 仲丁威
谱图信息:
最多检出来源 Homo sapiens(blood) 92.15%
分子结构信息
SMILES: CCC(C)C1=CC=CC=C1OC(=O)NC
InChI: InChI=1S/C12H17NO2/c1-4-9(2)10-7-5-6-8-11(10)15-12(14)13-3/h5-9H,4H2,1-3H3,(H,13,14)
描述信息
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
同义名列表
15 个代谢物同义名
2-(1-Methylpropyl)phenyl methylcarbamic acid; Methylcarbamic acid O-sec-butylphenyl ester; 2-(1-Methylpropyl)phenyl methylcarbamate; 2-Sec-butylphenyl N-methylcarbamic acid; Methylcarbamate O-sec-butylphenyl ester; 2-(butan-2-yl)phenyl N-methylcarbamate; 2-Sec-butylphenyl methylcarbamic acid; 2-Sec-butylphenyl N-methylcarbamate; O-Sec-butylphenyl N-methylcarbamate; 2-Sec-butylphenyl methylcarbamate; Fenobucarb; bassa; BPMC; Fenobucarb; Fenobucarb
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:34304
- KEGG: C14425
- PubChem: 19588
- HMDB: HMDB0252205
- Metlin: METLIN70052
- ChEMBL: CHEMBL226650
- Wikipedia: Fenobucarb
- chemspider: 18452
- CAS: 3766-81-2
- PMhub: MS000023717
- PubChem: 17395425
- NIKKAJI: J3.059G
- KNApSAcK: 34304
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zongzhe He, Chenglong Li, Weitong Xia, Zhen Wang, Rui Li, Yanqing Zhang, Minghua Wang. Comprehensive Enantioselectivity Evaluation of Insecticidal Activity and Mammalian Toxicity of Fenobucarb.
Journal of agricultural and food chemistry.
2022 May; 70(17):5330-5338. doi:
10.1021/acs.jafc.2c00093. [PMID: 35451821] - Guiling Yang, Chen Chen, Yijun Yu, Huiyu Zhao, Wen Wang, Yanhua Wang, Leiming Cai, Yueping He, Xinquan Wang. Combined effects of four pesticides and heavy metal chromium (Ⅵ) on the earthworm using avoidance behavior as an endpoint.
Ecotoxicology and environmental safety.
2018 Aug; 157(?):191-200. doi:
10.1016/j.ecoenv.2018.03.067. [PMID: 29621711] - Nguyen Thanh Tam, Håkan Berg, Jenny Laureus, Nguyen Van Cong, Michael Tedengren. Effects of Sequential Applications of Bassa 50EC (Fenobucarb) and Vitashield 40EC (Chlorpyrifos ethyl) on Acetylcholinesterase Activity in Climbing Perch (Anabas testudineus) Cultured in Rice Fields in the Mekong Delta, Vietnam.
Bulletin of environmental contamination and toxicology.
2016 Jul; 97(1):98-104. doi:
10.1007/s00128-016-1796-5. [PMID: 27075585] - Feng Jiang, Yixi Zhang, Huahua Sun, Xiangkun Meng, Haibo Bao, Jichao Fang, Zewen Liu. Identification of polymorphisms in Cyrtorhinus lividipennis RDL subunit contributing to fipronil sensitivity.
Pesticide biochemistry and physiology.
2015 Jan; 117(?):62-7. doi:
10.1016/j.pestbp.2014.10.010. [PMID: 25619913] - Ahmed Mostafa, Gregory Medley, Darren M Roberts, Mosaad Sayed Mohamed, Abdalla A Elshanawani, Michael S Roberts, Xin Liu. Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Aug; 879(23):2234-8. doi:
10.1016/j.jchromb.2011.06.006. [PMID: 21723210] - Yuko Ito, Tomomi Goto, Sadaji Yamada, Tsutomu Ohno, Hiroshi Matsumoto, Hisao Oka, Yoichiro Ito. Rapid determination of carbamate pesticides in food using dual counter-current chromatography directly interfaced with mass spectrometry.
Journal of chromatography. A.
2008 Apr; 1187(1-2):53-7. doi:
10.1016/j.chroma.2008.01.078. [PMID: 18295222] - C M P G Amorim, J R Albert-García, M C B S Montenegro, A N Araújo, J Martínez Calatayud. Photo-induced chemiluminometric determination of Karbutilate in a continuous-flow multicommutation assembly.
Journal of pharmaceutical and biomedical analysis.
2007 Jan; 43(2):421-7. doi:
10.1016/j.jpba.2006.07.006. [PMID: 16930910] - Yuko Ito, Tomomi Goto, Sadaji Yamada, Hiroshi Matsumoto, Hisao Oka, Nobuyuki Takahashi, Hiroyuki Nakazawa, Hisamitsu Nagase, Yoichiro Ito. Application of dual counter-current chromatography for rapid sample preparation of N-methylcarbamate pesticides in vegetable oil and citrus fruit.
Journal of chromatography. A.
2006 Mar; 1108(1):20-5. doi:
10.1016/j.chroma.2005.12.070. [PMID: 16445929] - Jialun Wu, Liqing Li, Yaohua Zou. Determination of carbamate insecticides in Chinese medicinal herbs by gas chromatography with a nitrogen-phosphorus detector.
Journal of AOAC International.
2005 Jul; 88(4):1261-4. doi:
. [PMID: 16152951] - T Ariyoshi, S Shiiba, H Hasegawa, K Arizono. Profile of metal-binding proteins and heme oxygenase in red carp treated with heavy metals, pesticides and surfactants.
Bulletin of environmental contamination and toxicology.
1990 Apr; 44(4):643-9. doi:
10.1007/bf01700889. [PMID: 2322691] - T Miyaoka, S Tsuda, Y Shirasu. Mechanism of potentiation of BPMC toxicity by fenthion pretreatment in mice.
Journal of pharmacobio-dynamics.
1986 Sep; 9(9):697-703. doi:
10.1248/bpb1978.9.697. [PMID: 3794990] - H Takahashi, T Miyaoka, S Tsuda, Y Shirasu. Potentiated toxicity of 2-sec-butylphenyl methylcarbamate (BPMC) by O,O-dimethyl O-(3-methyl-4-nitrophenyl)phosphorothioate (fenitrothion) in mice; relationship between acute toxicity and metabolism of BPMC.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1984 Oct; 4(5):718-23. doi:
10.1016/0272-0590(84)90092-7. [PMID: 6510602] - S Tsuda, T Miyaoka, M Iwasaki, Y Shirasu. Pharmacokinetic analysis of increased toxicity of 2-sec-butylphenyl methylcarbamate (BPMC) by fenitrothion pretreatment in mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1984 Oct; 4(5):724-30. doi:
10.1016/0272-0590(84)90093-9. [PMID: 6510603] - T Miyaoka, H Takahashi, S Tsuda, Y Shirasu. Potentiation of acute toxicity of 2-sec-butylphenyl N-methylcarbamate (BPMC) by fenthion in mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1984 Oct; 4(5):802-7. doi:
10.1016/0272-0590(84)90102-7. [PMID: 6510612] - M Ueji, J Kanazawa. Uptake and translocation of o-sec-butylphenyl N-methylcarbamate (BPMC) and O,O-diisopropyl S-benzyl phosphorothiolate (IBP) in rice plants applied as single and mixed preparations.
Bulletin of environmental contamination and toxicology.
1980 Feb; 24(2):204-10. doi:
10.1007/bf01608098. [PMID: 7362899]
