Isochamaejasmin (BioDeep_00000000920)

PANOMIX_OTCML-2023

代谢物信息卡片

(2S,3R)-3-[(2R,3S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

化学式: C30H22O10 (542.1212912)
中文名称: 异狼毒素
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 5%

Reviewed

Last reviewed on 2024-07-09.

Cite this Page

Isochamaejasmin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/isochamaejasmin (retrieved 2024-11-11) (BioDeep RN: BioDeep_00000000920). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1(O)=CC2O[C@H](C3C=CC(O)=CC=3)[C@@]([H])([C@]3([H])C(=O)C4=C(O)C=C(O)C=C4O[C@H]3C3=CC=C(O)C=C3)C(=O)C=2C(O)=C1
InChI: InChI=1S/C30H22O10/c31-15-5-1-13(2-6-15)29-25(27(37)23-19(35)9-17(33)11-21(23)39-29)26-28(38)24-20(36)10-18(34)12-22(24)40-30(26)14-3-7-16(32)8-4-14/h1-12,25-26,29-36H

描述信息

Chamaejasmin is a natural product found in Brackenridgea zanguebarica, Stellera chamaejasme, and other organisms with data available.
Isochamaejasmin is a biflavonoid that consists of two units of 5,7,4-trihydroxyflavanone joined together at position 3 and 3. It has a role as a plant metabolite. It is a biflavonoid and a hydroxyflavone.
Isochamaejasmin is a natural product found in Brackenridgea zanguebarica, Stellera chamaejasme, and Ormocarpum kirkii with data available.

同义名列表

13 个代谢物同义名

Chamaejasmin; 3-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; 3-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-chroman-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; [3,3-Bi-2H-1-benzopyran]-4,4(3H,3H)-dione, 5,5,7,7-tetrahydroxy-2,2-bis(4-hydroxyphenyl)-; Neochamaejasmine A; Neochamaejasmin A; MEGxp0_001158; ACon1_001326; (2S,3R)-3-[(2R,3S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; (2R,2S,3S,3R)-5,5,7,7-tetrahydroxy-2,2-bis(4-hydroxyphenyl)-2,2,3,3-tetrahydro-4H,4H-[3,3-bi-1-benzopyran]-4,4-dione; 3,3-Binaringenin; Isochamaejasmine; Isochamaejasmin

数据库引用编号

19 个数据库交叉引用编号

ChEBI: CHEBI:5994
KEGG: C09758
PubChem: 390362
PubChem: 390361
Metlin: METLIN985030
Metlin: METLIN47514
ChEMBL: CHEMBL467196
ChEMBL: CHEMBL3318021
LipidMAPS: LMPK12040001
MeSH: chamaejasmin
MeSH: isochamaejasmin
KNApSAcK: C00006420
CAS: 93859-63-3
medchemexpress: HY-126412
medchemexpress: HY-N3497
PMhub: MS000005038
KNApSAcK: C00000972
3DMET: B03256
NIKKAJI: J623.011C

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

1389743 - Brackenridgea zanguebarica: 10.1016/S0040-4039(01)91161-X
1389743 - Brackenridgea zanguebarica: 10.1039/P19870002809
2918710 - Daphne aurantiaca: 10.1248/CPB.59.653
77269 - Diphysa americana:
48133 - Diphysa robinioides:
289720 - Lithraea molleoides: 10.1055/S-2003-45096
2846702 - Ochna calodendron: 10.1016/S0367-326X(01)00286-6
77284 - Ormocarpum kirkii: 10.1016/J.PHYTOCHEM.2010.02.005
43851 - Schinus molle: 10.1055/S-2003-45096
142738 - Stellera chamaejasme:

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Yuanhang Ren, Qiang Li, Lidan Lu, Hong Jin, Ke Tao, Taiping Hou. Isochamaejasmin induces toxic effects on Helicoverpa zea via DNA damage and mitochondria-associated apoptosis. Pest management science. 2021 Jan; 77(1):557-567. doi: 10.1002/ps.6055. [PMID: 32815281]
Ahmed H H El-Desoky, Keisuke Eguchi, Hikaru Kato, Naoki Kishimoto, Shogo Misumi, Takashi Watanabe, Sachiko Tsukamoto. Chamaejasmins, cytotoxic guaiane sesquiterpenes from the root of Stellera chamaejasme L. Fitoterapia. 2020 Oct; 146(?):104714. doi: 10.1016/j.fitote.2020.104714. [PMID: 32858173]
Ludi Wang, Wei Yang, Siyang Wu, Shuyao Wang, Chen Kang, Xiaoli Ma, Yingfei Li, Chuan Li. Simultaneous determination of isochamaejasmin, neochamaejasmin A and aphnoretinin rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study of Stellera chamaejasme L. extract. Biomedical chromatography : BMC. 2018 May; 32(5):e4162. doi: 10.1002/bmc.4162. [PMID: 29235122]
Sumin Qian, Meng Li. Chamaejasmine induces apoptosis in HeLa cells through the PI3K/Akt signaling pathway. Anti-cancer drugs. 2017 01; 28(1):40-50. doi: 10.1097/cad.0000000000000424. [PMID: 27557139]
Shou-De Zhang, Lei Shan, Wei Li, Hong-Lin Li, Wei-Dong Zhang. Isochamaejasmin induces apoptosis in leukemia cells through inhibiting Bcl-2 family proteins. Chinese journal of natural medicines. 2015 Sep; 13(9):660-6. doi: 10.1016/s1875-5364(15)30063-7. [PMID: 26412425]
Oue-artorn Rajachan, Somdej Kanokmedhakul, Phitak Nasomjai, Kwanjai Kanokmedhakul. Chemical constituents and biological activities from roots of Enkleia siamensis. Natural product research. 2014; 28(4):268-70. doi: 10.1080/14786419.2013.838241. [PMID: 24047498]
Li-Yin Chen, Ih-Sheng Chen, Chien-Fang Peng. Structural elucidation and bioactivity of biflavonoids from the stems of Wikstroemia taiwanensis. International journal of molecular sciences. 2012; 13(1):1029-1038. doi: 10.3390/ijms13011029. [PMID: 22312302]
Qinghai Tian, Jing Li, Xin Xie, Meiling Sun, Hairong Sang, Caihong Zhou, Tianying An, Lihong Hu, Richard D Ye, Ming-Wei Wang. Stereospecific induction of nuclear factor-kappaB activation by isochamaejasmin. Molecular pharmacology. 2005 Dec; 68(6):1534-42. doi: 10.1124/mol.105.014720. [PMID: 16141313]