Scaldip (BioDeep_00000865575)

Main id: BioDeep_00000001669

 

Volatile Flavor Compounds


代谢物信息卡片


InChI=1\C12H11N\c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12\h1-10,13

化学式: C12H11N (169.0891446)
中文名称: 二苯胺, 甲醇中二苯胺溶液
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)NC2=CC=CC=C2
InChI: InChI=1S/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H

描述信息

同义名列表

59 个代谢物同义名

InChI=1\C12H11N\c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12\h1-10,13; Diphenylamine, reaction product with 2,2,4-trimethylpentene; Styrene, reaction product with diphenylamine; EPA Pesticide Chemical Code 038501; N-Phenylbenzenamine, styrenated; Styrenated diphenylamine; Benzene, (phenylamino)-; Benzenamine, N-phenyl-; N-Fenylanilin [Czech]; (Phenylamino)benzene; N-Phenylbenzenamine; Poly(diphenylamine); Difenylamin [Czech]; Aniline, N-phenyl-; Benzene, anilino-; N,N-Diphenylamine; EINECS 204-539-4; NO-Scald dpa 283; EINECS 270-485-3; Caswell No. 398; NCGC00090889-01; di(phenyl)amine; N-phenylaniline; NCGC00090889-02; Anilinobenzene; 112763_ALDRICH; Deccoscald 282; Diphenyl-amine; Naugalube 428l; Phenylaniline; PS427_SUPELCO; Oprea1_815288; Diphenylamine; 33149_RIEDEL; ZINC00967716; 45456_RIEDEL; C6H5-NH-C6H5; 242586_SIAL; NSC 215210; 86352-05-8; CCRIS 4699; C.I. 10355; CHEBI:4640; Shield dpa; Big dipper; AI3-00781; NSC215210; ST5406192; HSDB 1108; no Scald; NO-Scald; CI 10355; WLN: RMR; 122-39-4; Scaldip; C11016; DFA; Diphenylamine; Diphenylamine



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yi-Dan Ma, Huan Zhou, Guo-Tai Lin, Ke-Huan Wu, Gong Xu, Xili Liu, Dan Xu. Design, Synthesis, and Fungicidal Activities of Novel N-(Pyrazol-5-yl)benzamide Derivatives Containing a Diphenylamine Moiety. Journal of agricultural and food chemistry. 2024 Mar; 72(12):6691-6701. doi: 10.1021/acs.jafc.3c07567. [PMID: 38498985]
  • Peter Lees, Pierre-Louis Toutain, Jonathan Elliott, Jerome M Giraudel, Ludovic Pelligand, Jonathan N King. Pharmacology, safety, efficacy and clinical uses of the COX-2 inhibitor robenacoxib. Journal of veterinary pharmacology and therapeutics. 2022 Jul; 45(4):325-351. doi: 10.1111/jvp.13052. [PMID: 35460083]
  • Verónica Vieitez, Victor López-Rámis, Rafael Barrera, Ignacio A Gómez de Segura. Serum C-reactive protein and iron levels following gonadectomy are not modified by perioperative administration of robenacoxib to dogs. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2022 Jan; 86(1):40-47. doi: . [PMID: 34975221]
  • Jonathan N King, Wolfgang Seewald, Sophie Forster, Gabriele Friton, Derek E Adrian, B Duncan X Lascelles. Clinical safety of robenacoxib in cats with chronic musculoskeletal disease. Journal of veterinary internal medicine. 2021 Sep; 35(5):2384-2394. doi: 10.1111/jvim.16148. [PMID: 34196973]
  • L Hinder, A L Pfaff, R E Emmerich, S Michels, M Schlitzer, C Culmsee. Characterization of Novel Diphenylamine Compounds as Ferroptosis Inhibitors. The Journal of pharmacology and experimental therapeutics. 2021 08; 378(2):184-196. doi: 10.1124/jpet.121.000534. [PMID: 34011530]
  • Juliette Raulic, Francis Beaudry, Guy Beauchamp, Marion Jalenques, Noémie Summa, Stéphane Lair, Wahiba Ait Youcef, Claire Vergneau-Grosset. PHARMACOKINETIC, PHARMACODYNAMIC, AND TOXICOLOGY STUDY OF ROBENACOXIB IN RAINBOW TROUT (ONCORHYNCHUS MYKISS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2021 Jun; 52(2):529-537. doi: 10.1638/2020-0130. [PMID: 34130395]
  • Jonathan N King, Martin Jung. Determination of the route of excretion of robenacoxib (Onsior™) in cats and dogs: A pilot study. Journal of veterinary pharmacology and therapeutics. 2021 May; 44(3):411-416. doi: 10.1111/jvp.12973. [PMID: 33881783]
  • Yu Katata, Shin-Ichi Inoue, Atsuko Asao, Shuhei Kobayashi, Hitoshi Terui, Aya Inoue-Shibui, Taiki Abe, Tetsuya Niihori, Setsuya Aiba, Naoto Ishii, Shigeo Kure, Yoko Aoki. Costello syndrome model mice with a HrasG12S/+ mutation are susceptible to develop house dust mite-induced atopic dermatitis. Cell death & disease. 2020 08; 11(8):617. doi: 10.1038/s41419-020-02845-8. [PMID: 32792500]
  • Aigui Zhang, Ying Yue, Jian Yang, Jiaxing Shi, Ke Tao, Hong Jin, Taiping Hou. Design, Synthesis, and Antifungal Activities of Novel Aromatic Carboxamides Containing a Diphenylamine Scaffold. Journal of agricultural and food chemistry. 2019 May; 67(17):5008-5016. doi: 10.1021/acs.jafc.9b00151. [PMID: 30977370]
  • Zhe Lu, Amila O De Silva, Wenjia Zhou, Gerald R Tetreault, Shane R de Solla, Patricia A Fair, Magali Houde, Greg Bossart, Derek C G Muir. Substituted diphenylamine antioxidants and benzotriazole UV stabilizers in blood plasma of fish, turtles, birds and dolphins from North America. The Science of the total environment. 2019 Jan; 647(?):182-190. doi: 10.1016/j.scitotenv.2018.07.405. [PMID: 30081360]
  • Sukanya Ramaraj, Mani Sakthivel, Shen-Ming Chen, Kuo-Chuan Ho. Ultrasound-assisted synthesis of two-dimensional layered ytterbium substituted molybdenum diselenide nanosheets with excellent electrocatalytic activity for the electrochemical detection of diphenylamine anti-scald agent in fruit extract. Ultrasonics sonochemistry. 2019 Jan; 50(?):265-277. doi: 10.1016/j.ultsonch.2018.09.028. [PMID: 30287180]
  • Yasmin Schuermann, Monique T Rovani, Bernardo Gasperin, Rogério Ferreira, Juliana Ferst, Ejimedo Madogwe, Paulo B Gonçalves, Vilceu Bordignon, Raj Duggavathi. ERK1/2-dependent gene expression in the bovine ovulating follicle. Scientific reports. 2018 11; 8(1):16170. doi: 10.1038/s41598-018-34015-4. [PMID: 30385793]
  • Norihiko Oyama, Tadashi Sano, Mizuki Yamamori, Jun Tamura, Mohammed Ahmed Umar, Yusuke Endo, Yusyun Ishikawa, Akifumi Itoh, Kenjirou Miyoshi, Kazuto Yamashita. Influence of sevoflurane anesthesia with mechanical ventilation and fluid-therapy on distribution of subcutaneously administered robenacoxib in dogs. The Journal of veterinary medical science. 2018 Sep; 80(9):1450-1455. doi: 10.1292/jvms.17-0356. [PMID: 30078791]
  • Céline E Toutain, Patrick Brossard, Stephen B King, Rainer Helbig. Six-month safety evaluation of robenacoxib tablets (Onsior™) in dogs after daily oral administrations. BMC veterinary research. 2018 Aug; 14(1):242. doi: 10.1186/s12917-018-1566-1. [PMID: 30119677]
  • Evangelos Karagiannis, Michail Michailidis, Georgia Tanou, Martina Samiotaki, Katerina Karamanoli, Evangelia Avramidou, Ioannis Ganopoulos, Panagiotis Madesis, Athanassios Molassiotis. Ethylene -dependent and -independent superficial scald resistance mechanisms in 'Granny Smith' apple fruit. Scientific reports. 2018 07; 8(1):11436. doi: 10.1038/s41598-018-29706-x. [PMID: 30061655]
  • Gong Yihui, Jun Song, Lina Du, Mindy Vinqvist, Leslie Campbell Palmer, Sherry Fillmore, XueQun Pang, ZhaoQi Zhang. Characterization of laccase from apple fruit during postharvest storage and its response to diphenylamine and 1-methylcyclopropene treatments. Food chemistry. 2018 Jul; 253(?):314-321. doi: 10.1016/j.foodchem.2018.01.142. [PMID: 29502838]
  • Cuiping Li, Weiyi Lai, Hailin Wang. An Alternative Culture Method to Maintain Genomic Hypomethylation of Mouse Embryonic Stem Cells Using MEK Inhibitor PD0325901 and Vitamin C. Journal of visualized experiments : JoVE. 2018 06; ?(136):. doi: 10.3791/56391. [PMID: 29912180]
  • Matthew A Summers, Emily R Vasiljevski, Kathy Mikulec, Lauren Peacock, David G Little, Aaron Schindeler. Developmental dosing with a MEK inhibitor (PD0325901) rescues myopathic features of the muscle-specific but not limb-specific Nf1 knockout mouse. Molecular genetics and metabolism. 2018 04; 123(4):518-525. doi: 10.1016/j.ymgme.2018.02.009. [PMID: 29477258]
  • Zev A Wainberg, Maria Alsina, Heloisa P Soares, Irene Braña, Carolyn D Britten, Gianluca Del Conte, Patrick Ezeh, Brett Houk, Kenneth A Kern, Stephen Leong, Nuzhat Pathan, Kristen J Pierce, Lillian L Siu, Jennifer Vermette, Josep Tabernero. A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer. Targeted oncology. 2017 Dec; 12(6):775-785. doi: 10.1007/s11523-017-0530-5. [PMID: 29067643]
  • Jian-Zhong Xu, Wei-Guo Zhang. Menaquinone-7 production from maize meal hydrolysate by Bacillus isolates with diphenylamine and analogue resistance. Journal of Zhejiang University. Science. B. 2017 Jun; 18(6):462-473. doi: 10.1631/jzus.b1600127. [PMID: 28585422]
  • Jean-Luc Van Laethem, Hanno Riess, Jacek Jassem, Michael Haas, Uwe M Martens, Colin Weekes, Marc Peeters, Paul Ross, John Bridgewater, Bohuslav Melichar, Stefano Cascinu, Piotr Saramak, Patrick Michl, David Van Brummelen, Alberto Zaniboni, Wollf Schmiegel, Svein Dueland, Marius Giurescu, Vittorio L Garosi, Katrin Roth, Anke Schulz, Henrik Seidel, Prabhu Rajagopalan, Michael Teufel, Barrett H Childs. Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer. Targeted oncology. 2017 02; 12(1):97-109. doi: 10.1007/s11523-016-0469-y. [PMID: 27975152]
  • A Panteri, A Kukk, C Desevaux, W Seewald, J N King. Effect of benazepril and robenacoxib and their combination on glomerular filtration rate in dogs. Journal of veterinary pharmacology and therapeutics. 2017 Jan; 40(1):44-56. doi: 10.1111/jvp.12325. [PMID: 27302598]
  • Roxana Sühring, Xavier Ortiz, Miren Pena-Abaurrea, Karl J Jobst, Marko Freese, Jan-Dag Pohlmann, Lasse Marohn, Ralf Ebinghaus, Sean Backus, Reinhold Hanel, Eric J Reiner. Evidence for High Concentrations and Maternal Transfer of Substituted Diphenylamines in European Eels Analyzed by Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry and Gas Chromatography-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Environmental science & technology. 2016 12; 50(23):12678-12685. doi: 10.1021/acs.est.6b04382. [PMID: 27791360]
  • C Marcela Diaz-Montero, Frances J Mao, John Barnard, Yvonne Parker, Maryam Zamanian-Daryoush, John J Pink, James H Finke, Brian I Rini, Daniel J Lindner. MEK inhibition abrogates sunitinib resistance in a renal cell carcinoma patient-derived xenograft model. British journal of cancer. 2016 10; 115(8):920-928. doi: 10.1038/bjc.2016.263. [PMID: 27560553]
  • Selvakumar Subramaniam, Mehmet Hakan Ozdener, Souleymane Abdoul-Azize, Katsuyoshi Saito, Bilal Malik, Guillaume Maquart, Toshihiro Hashimoto, Philippe Marambaud, Mourad Aribi, Michael G Tordoff, Philippe Besnard, Naim Akhtar Khan. ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2016 10; 30(10):3489-3500. doi: 10.1096/fj.201600422r. [PMID: 27358389]
  • Zhe Lu, Thomas E Peart, Cyril J Cook, Amila O De Silva. Simultaneous determination of substituted diphenylamine antioxidants and benzotriazole ultra violet stabilizers in blood plasma and fish homogenates by ultra high performance liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. A. 2016 Aug; 1461(?):51-8. doi: 10.1016/j.chroma.2016.07.027. [PMID: 27425756]
  • Jonathan N King, Stephen King, Steven C Budsberg, B Duncan X Lascelles, Stephen E Bienhoff, Linda M Roycroft, Elizabeth S Roberts. Clinical safety of robenacoxib in feline osteoarthritis: results of a randomized, blinded, placebo-controlled clinical trial. Journal of feline medicine and surgery. 2016 08; 18(8):632-42. doi: 10.1177/1098612x15590870. [PMID: 26058587]
  • Domingos Pf Almeida, Rita Carvalho, Eve Dupille. Efficacy of 1-methylcyclopropene on the mitigation of storage disorders of "Rocha" pear under normal refrigerated and controlled atmospheres. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2016 Jul; 22(5):399-409. doi: 10.1177/1082013215610026. [PMID: 26437671]
  • Jonathan N King, Alessandro Panteri, Melanie Graille, Wolfgang Seewald, Gabriele Friton, Cyril Desevaux. Effect of benazepril, robenacoxib and their combination on glomerular filtration rate in cats. BMC veterinary research. 2016 Jun; 12(1):124. doi: 10.1186/s12917-016-0734-4. [PMID: 27338786]
  • Alex A Adjei, Donald A Richards, Anthony El-Khoueiry, Fadi Braiteh, Carlos H R Becerra, Joe J Stephenson, Aram F Hezel, Morris Sherman, Lawrence Garbo, Diane P Leffingwell, Cory Iverson, Jeffrey N Miner, Zancong Shen, Li-Tain Yeh, Sonny Gunawan, David M Wilson, Kimberly J Manhard, Prabhu Rajagopalan, Heiko Krissel, Neil J Clendeninn. A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 05; 22(10):2368-76. doi: 10.1158/1078-0432.ccr-15-1681. [PMID: 26644411]
  • Di Li, Linli Wang, Jundi Hou, Qun Shen, Qianyu Chen, Xiaoshan Wang, Juan Du, Xiujuan Cai, Yongli Shan, Tian Zhang, Tiancheng Zhou, Xi Shi, Yuhua Li, Hua Zhang, Guangjin Pan. Optimized Approaches for Generation of Integration-free iPSCs from Human Urine-Derived Cells with Small Molecules and Autologous Feeder. Stem cell reports. 2016 05; 6(5):717-728. doi: 10.1016/j.stemcr.2016.04.001. [PMID: 27132887]
  • Huichao Li, Aiying Guan, Guang Huang, Chang-Ling Liu, Zhinian Li, Yong Xie, Jie Lan. Design, synthesis and structure-activity relationship of novel diphenylamine derivatives. Bioorganic & medicinal chemistry. 2016 Feb; 24(3):453-61. doi: 10.1016/j.bmc.2015.09.032. [PMID: 26432603]
  • Xueying Luo, Binlong Zhong, Xian Hong, Yurong Cui, Ying Gao, Mengmeng Yin, Ming Tang, Jürgen Hescheler, Jiaoya Xi. Puerarin Exerts a Delayed Inhibitory Effect on the Proliferation of Cardiomyocytes Derived from Murine ES Cells via Slowing Progression through G2/M Phase. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2016; 38(4):1333-42. doi: 10.1159/000443077. [PMID: 27008508]
  • L Pelligand, N Suemanotham, J N King, W Seewald, H Syme, K Smith, P Lees, J Elliott. Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC veterinary research. 2015 Dec; 11(?):296. doi: 10.1186/s12917-015-0598-z. [PMID: 26634699]
  • Justyna Sekuła, Joanna Nizioł, Maria Misiorek, Paulina Dec, Agnieszka Wrona, Adrian Arendowski, Tomasz Ruman. Gold nanoparticle-enhanced target for MS analysis and imaging of harmful compounds in plant, animal tissue and on fingerprint. Analytica chimica acta. 2015 Oct; 895(?):45-53. doi: 10.1016/j.aca.2015.09.003. [PMID: 26454458]
  • Vaibhav Sidarala, Rajakrishnan Veluthakal, Khadija Syeda, Anjaneyulu Kowluru. EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells. Cellular signalling. 2015 Jun; 27(6):1159-67. doi: 10.1016/j.cellsig.2015.02.020. [PMID: 25725286]
  • Bas Brinkhof, Helena T A van Tol, Marian J A Groot Koerkamp, Frank M Riemers, Sascha G IJzer, Kaveh Mashayekhi, Henk P Haagsman, Bernard A J Roelen. A mRNA landscape of bovine embryos after standard and MAPK-inhibited culture conditions: a comparative analysis. BMC genomics. 2015 Apr; 16(?):277. doi: 10.1186/s12864-015-1448-x. [PMID: 25888366]
  • Patricia Tomas-Martin, Aida M Lopez-Guerrero, Vanessa Casas-Rua, Eulalia Pozo-Guisado, Francisco Javier Martin-Romero. Phospho-STIM1 is a downstream effector that mediates the signaling triggered by IGF-1 in HEK293 cells. Cellular signalling. 2015 Mar; 27(3):545-54. doi: 10.1016/j.cellsig.2014.12.017. [PMID: 25562429]
  • Mehdi Pirouz, Ali Rahjouei, Farnaz Shamsi, Kolja Neil Eckermann, Gabriela Salinas-Riester, Claudia Pommerenke, Michael Kessel. Destabilization of pluripotency in the absence of Mad2l2. Cell cycle (Georgetown, Tex.). 2015; 14(10):1596-610. doi: 10.1080/15384101.2015.1026485. [PMID: 25928475]
  • M Szweda, J Szarek, M Lew, A Szarek-Bęska, D Gulda. Can liquorice extract and herbal solution prevent colonic mucosa damage caused by robenacoxib in dogs?. Polish journal of veterinary sciences. 2015; 18(4):793-8. doi: 10.1515/pjvs-2015-0103. [PMID: 26812822]
  • Joao A Paulo, Fiona E McAllister, Robert A Everley, Sean A Beausoleil, Alexander S Banks, Steven P Gygi. Effects of MEK inhibitors GSK1120212 and PD0325901 in vivo using 10-plex quantitative proteomics and phosphoproteomics. Proteomics. 2015 Jan; 15(2-3):462-73. doi: 10.1002/pmic.201400154. [PMID: 25195567]
  • L Pelligand, J N King, V Hormazabal, P L Toutain, J Elliott, P Lees. Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation. Journal of veterinary pharmacology and therapeutics. 2014 Aug; 37(4):354-66. doi: 10.1111/jvp.12107. [PMID: 24628410]
  • Farnoosh Attari, Houri Sepehri, Hassan Ansari, Seyedeh-Nafiseh Hassani, Fereshteh Esfandiari, Behrouz Asgari, Abdolhossein Shahverdi, Hossein Baharvand. Efficient induction of pluripotency in primordial germ cells by dual inhibition of TGF-β and ERK signaling pathways. Stem cells and development. 2014 May; 23(10):1050-61. doi: 10.1089/scd.2013.0438. [PMID: 24382167]
  • Xiaofei Li, Yuhua Wu, Li Zhang, Yinglong Cao, Yunjing Li, Jun Li, Li Zhu, Gang Wu. Comparison of three common DNA concentration measurement methods. Analytical biochemistry. 2014 Apr; 451(?):18-24. doi: 10.1016/j.ab.2014.01.016. [PMID: 24495734]
  • Susana Bequer Urbano, Cecilia Di Capua, Néstor Cortez, María E Farías, Héctor M Alvarez. Triacylglycerol accumulation and oxidative stress in Rhodococcus species: differential effects of pro-oxidants on lipid metabolism. Extremophiles : life under extreme conditions. 2014 Mar; 18(2):375-84. doi: 10.1007/s00792-013-0623-8. [PMID: 24420608]
  • Olfat G Shaker, Shereen O Tawfic, Amira M El-Tawdy, Mohamed H M El-Komy, Manal El Menyawi, Ahmed A Heikal. Expression of TNF-α, APRIL and BCMA in Behcet's disease. Journal of immunology research. 2014; 2014(?):380405. doi: 10.1155/2014/380405. [PMID: 25759827]
  • Hai-Ying Wang, Liang-Feng Chen, Xiu-Ling Zhu, Chao Wang, Yu Wan, Hui Wu. Spectral studies of multi-branched fluorescence dyes based on triphenylpyridine core. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2014; 121(?):355-62. doi: 10.1016/j.saa.2013.10.087. [PMID: 24287048]
  • Magdalena Szweda, Józef Szarek, Krystyna Dublan, Tomasz Męcik-Kronenberg, Zdzisław Kiełbowicz, Marcin Bigoszewski. Effect of mucoprotective plant-derived therapies on damage to colonic mucosa caused by carprofen and robenacoxib administered to healthy dogs for 21 days. The veterinary quarterly. 2014; 34(4):185-93. doi: 10.1080/01652176.2014.968939. [PMID: 25330194]
  • Arukali Sammaiah, Korlipara Venkata Padmaja, Rachapudi Badari Narayna Prasad. Synthesis of epoxy jatropha oil and its evaluation for lubricant properties. Journal of oleo science. 2014; 63(6):637-43. doi: 10.5650/jos.ess13172. [PMID: 24829128]
  • Daofang Ding, Linghui Li, Yi Song, Guoqing DU, Xiaoen Wei, Yuelong Cao. [MAPK-ERK1/2 signaling pathway regulates osteogenic gene expression in rat osteoblasts in vitro]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2013 Oct; 33(10):1432-6. doi: NULL. [PMID: 24144741]
  • M Fink, I Letellier, M Peyrou, J P Mochel, M Jung, J N King, P Gruet, J M Giraudel. Population pharmacokinetic analysis of blood concentrations of robenacoxib in dogs with osteoarthritis. Research in veterinary science. 2013 Oct; 95(2):580-7. doi: 10.1016/j.rvsc.2013.04.021. [PMID: 23726662]
  • Roberta Schmieder, Florian Puehler, Roland Neuhaus, Maria Kissel, Alex A Adjei, Jeffrey N Miner, Dominik Mumberg, Karl Ziegelbauer, Arne Scholz. Allosteric MEK1/2 inhibitor refametinib (BAY 86-9766) in combination with sorafenib exhibits antitumor activity in preclinical murine and rat models of hepatocellular carcinoma. Neoplasia (New York, N.Y.). 2013 Oct; 15(10):1161-71. doi: 10.1593/neo.13812. [PMID: 24204195]
  • Ingo V Hartung, Marion Hitchcock, Florian Pühler, Roland Neuhaus, Arne Scholz, Stefanie Hammer, Kirstin Petersen, Gerhard Siemeister, Dominic Brittain, Roman C Hillig. Optimization of allosteric MEK inhibitors. Part 1: Venturing into underexplored SAR territories. Bioorganic & medicinal chemistry letters. 2013 Apr; 23(8):2384-90. doi: 10.1016/j.bmcl.2013.02.028. [PMID: 23474388]
  • David Bennett, Peter David Eckersall, Mary Waterston, Veronica Marchetti, Alessandra Rota, Eilidh McCulloch, Silvia Sbrana. The effect of robenacoxib on the concentration of C-reactive protein in synovial fluid from dogs with osteoarthritis. BMC veterinary research. 2013 Mar; 9(?):42. doi: 10.1186/1746-6148-9-42. [PMID: 23452411]
  • Jonathan N King, Martin Jung, Max P Maurer, Vincent B Schmid, Wolfgang Seewald, Peter Lees. Effects of route of administration and feeding schedule on pharmacokinetics of robenacoxib in cats. American journal of veterinary research. 2013 Mar; 74(3):465-72. doi: 10.2460/ajvr.74.3.465. [PMID: 23438125]
  • Colin D Weekes, Daniel D Von Hoff, Alex A Adjei, Diane P Leffingwell, S Gail Eckhardt, Lia Gore, Karl D Lewis, Glen J Weiss, Ramesh K Ramanathan, Grace K Dy, Wen W Ma, Beth Sheedy, Cory Iverson, Jeffrey N Miner, Zancong Shen, Li-Tain Yeh, Ronald L Dubowy, Michael Jeffers, Prabhu Rajagopalan, Neil J Clendeninn. Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Mar; 19(5):1232-43. doi: 10.1158/1078-0432.ccr-12-3529. [PMID: 23434733]
  • Alexander Zarbock, Jan Rossaint. L-selectin shedding by NSAIDs: old friends in new dresses. European journal of immunology. 2013 Jan; 43(1):50-4. doi: 10.1002/eji.201243166. [PMID: 23322695]
  • Tobias M Gorges, Johanna Schiller, Arndt Schmitz, Daniel Schuetzmann, Christoph Schatz, Thomas M Zollner, Thomas Krahn, Oliver von Ahsen. Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2012 Sep; 17(6):498-506. doi: 10.3109/1354750x.2012.689133. [PMID: 22616911]
  • Duncan G G McMillan, Sophie J Marritt, Julea N Butt, Lars J C Jeuken. Menaquinone-7 is specific cofactor in tetraheme quinol dehydrogenase CymA. The Journal of biological chemistry. 2012 Apr; 287(17):14215-25. doi: 10.1074/jbc.m112.348813. [PMID: 22393052]
  • Martin Y H Zhang, Daniel Ranch, Renata C Pereira, Harvey J Armbrecht, Anthony A Portale, Farzana Perwad. Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice. Endocrinology. 2012 Apr; 153(4):1806-16. doi: 10.1210/en.2011-1831. [PMID: 22334725]
  • Salim Salih Al-Rejaie, Hatem Mustafa Abuohashish, Osama Abdelrahman Alkhamees, Abdulaziz Mohammed Aleisa, Abdulaziz S Alroujayee. Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats. Lipids in health and disease. 2012 Mar; 11(?):41. doi: 10.1186/1476-511x-11-41. [PMID: 22423898]
  • Carla Ribeiro, Lucieli T Cambri, Rodrigo A Dalia, Michel B Araújo, Ana C Ghezzi, Leandro P Moura, Gustavo G Araújo, Jose D Botezelli, Maria Ar Mello. Muscle protein metabolism in neonatal alloxan-administered rats: effects of continuous and intermittent swimming training. Diabetology & metabolic syndrome. 2012 Feb; 4(1):5. doi: 10.1186/1758-5996-4-5. [PMID: 22309804]
  • Ta-Chun Hang, Douglas A Lauffenburger, Linda G Griffith, Donna B Stolz. Lipids promote survival, proliferation, and maintenance of differentiation of rat liver sinusoidal endothelial cells in vitro. American journal of physiology. Gastrointestinal and liver physiology. 2012 Feb; 302(3):G375-88. doi: 10.1152/ajpgi.00288.2011. [PMID: 22075778]
  • Selva Kumar Sivagnanam, Mudiganti Ram Krishna Rao, Maruthaiveeran Periyasamy Balasubramanian. Chemotherapeutic Efficacy of Indigofera aspalathoides on 20-Methylcholanthrene-Induced Fibrosarcoma in Rats. ISRN pharmacology. 2012; 2012(?):134356. doi: 10.5402/2012/134356. [PMID: 22530134]
  • Dominic Sophia, Paramasivam Ragavendran, Chinthamony Arul Raj, Velliyur Kanniappan Gopalakrishnan. Protective effect of Emilia sonchifolia (L.) against high protein diet induced oxidative stress in pancreas of Wistar rats. Journal of pharmacy & bioallied sciences. 2012 Jan; 4(1):60-5. doi: 10.4103/0975-7406.92735. [PMID: 22368400]
  • Maitham A Khajah, Sanaa Al Saleh, Princy M Mathew, Yunus A Luqmani. Differential effect of growth factors on invasion and proliferation of endocrine resistant breast cancer cells. PloS one. 2012; 7(7):e41847. doi: 10.1371/journal.pone.0041847. [PMID: 22860018]
  • Seung Hee Kang, Hee-Jeong Cho, Gayong Shim, Sangbin Lee, Su-Hyeon Kim, Han-Gon Choi, Chan-Wha Kim, Yu-Kyoung Oh. Cationic liposomal co-delivery of small interfering RNA and a MEK inhibitor for enhanced anticancer efficacy. Pharmaceutical research. 2011 Dec; 28(12):3069-78. doi: 10.1007/s11095-011-0569-4. [PMID: 21879387]
  • Santosh Soparawalla, Fatkhulla K Tadjimukhamedov, Joshua S Wiley, Zheng Ouyang, R Graham Cooks. In situ analysis of agrochemical residues on fruit using ambient ionization on a handheld mass spectrometer. The Analyst. 2011 Nov; 136(21):4392-6. doi: 10.1039/c1an15493a. [PMID: 21892448]
  • Jeffrey A Harvey, Rieta Gols. Population-related variation in plant defense more strongly affects survival of an herbivore than its solitary parasitoid wasp. Journal of chemical ecology. 2011 Oct; 37(10):1081-90. doi: 10.1007/s10886-011-0024-3. [PMID: 21987026]
  • Nan Cao, Jing Liao, Zumei Liu, Wenmin Zhu, Jia Wang, Lijun Liu, Lili Yu, Ping Xu, Chun Cui, Lei Xiao, Huang-Tian Yang. In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes. Cell research. 2011 Sep; 21(9):1316-31. doi: 10.1038/cr.2011.48. [PMID: 21423272]
  • David R Rudell, David A Buchanan, Rachel S Leisso, Bruce D Whitaker, James P Mattheis, Yanmin Zhu, Vijay Varanasi. Ripening, storage temperature, ethylene action, and oxidative stress alter apple peel phytosterol metabolism. Phytochemistry. 2011 Aug; 72(11-12):1328-40. doi: 10.1016/j.phytochem.2011.04.018. [PMID: 21665233]
  • Daniel Ranch, Martin Yh Zhang, Anthony A Portale, Farzana Perwad. Fibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2011 Aug; 26(8):1883-90. doi: 10.1002/jbmr.401. [PMID: 21472778]
  • Paul Bamborough, Murray J Brown, John A Christopher, Chun-wa Chung, Geoff W Mellor. Selectivity of kinase inhibitor fragments. Journal of medicinal chemistry. 2011 Jul; 54(14):5131-43. doi: 10.1021/jm200349b. [PMID: 21699136]
  • J N King, J P Arnaud, E I Goldenthal, P Gruet, M Jung, W Seewald, P Lees. Robenacoxib in the dog: target species safety in relation to extent and duration of inhibition of COX-1 and COX-2. Journal of veterinary pharmacology and therapeutics. 2011 Jun; 34(3):298-311. doi: 10.1111/j.1365-2885.2010.01209.x. [PMID: 21492194]
  • Jeffrey A Harvey, Nicole M van Dam, Ciska E Raaijmakers, James M Bullock, Rieta Gols. Tri-trophic effects of inter- and intra-population variation in defence chemistry of wild cabbage (Brassica oleracea). Oecologia. 2011 Jun; 166(2):421-31. doi: 10.1007/s00442-010-1861-4. [PMID: 21140168]
  • Abdelgadir A Abdelgadir, Elhadi M Ahmed, Mahgoub Sharif Eltohami. Isolation, Characterization and Quantity Determination of Aristolochic Acids, Toxic Compounds in Aristolochia bracteolata L. Environmental health insights. 2011 Feb; 5(?):1-8. doi: 10.4137/ehi.s6292. [PMID: 21487531]
  • Julia V Bugrysheva, Henry P Godfrey, Ira Schwartz, Felipe C Cabello. Patterns and regulation of ribosomal RNA transcription in Borrelia burgdorferi. BMC microbiology. 2011 Jan; 11(?):17. doi: 10.1186/1471-2180-11-17. [PMID: 21251259]
  • Monika Hlavová, Mária Čížková, Milada Vítová, Kateřina Bišová, Vilém Zachleder. DNA damage during G2 phase does not affect cell cycle progression of the green alga Scenedesmus quadricauda. PloS one. 2011; 6(5):e19626. doi: 10.1371/journal.pone.0019626. [PMID: 21603605]
  • Subhankari Prasad Chakraborty, Santanu Kar Mahapatra, Sumanta Kumar Sahu, Sabyasachi Das, Satyajit Tripathy, Sandeep Dash, Panchanan Pramanik, Somenath Roy. Internalization of Staphylococcus aureus in lymphocytes induces oxidative stress and DNA fragmentation: possible ameliorative role of nanoconjugated vancomycin. Oxidative medicine and cellular longevity. 2011; 2011(?):942123. doi: 10.1155/2011/942123. [PMID: 21941607]
  • Baldo F Cordero, Irina Obraztsova, Inmaculada Couso, Rosa Leon, Maria Angeles Vargas, Herminia Rodriguez. Enhancement of lutein production in Chlorella sorokiniana (Chorophyta) by improvement of culture conditions and random mutagenesis. Marine drugs. 2011; 9(9):1607-1624. doi: 10.3390/md9091607. [PMID: 22131961]
  • Subhankari Prasad Chakraborty, Santanu Karmahapatra, Sumanta Kumar Sahu, Panchanan Pramanik, Somenath Roy. Amelioratory Effect of Nanoconjugated Vancomycin on Spleen during VRSA-Induced Oxidative Stress. Pathology research international. 2011; 2011(?):420198. doi: 10.4061/2011/420198. [PMID: 21785683]
  • Meng-Jun Hu, Kerik D Cox, Guido Schnabel, Chao-Xi Luo. Monilinia species causing brown rot of peach in China. PloS one. 2011; 6(9):e24990. doi: 10.1371/journal.pone.0024990. [PMID: 21980371]
  • Conrad Johanson, Edward Stopa, Paul McMillan, Daniel Roth, Juergen Funk, Georg Krinke. The distributional nexus of choroid plexus to cerebrospinal fluid, ependyma and brain: toxicologic/pathologic phenomena, periventricular destabilization, and lesion spread. Toxicologic pathology. 2011 Jan; 39(1):186-212. doi: 10.1177/0192623310394214. [PMID: 21189316]
  • Joni Macdonald, James D Glover, Lorna Taylor, Helen M Sang, Michael J McGrew. Characterisation and germline transmission of cultured avian primordial germ cells. PloS one. 2010 Nov; 5(11):e15518. doi: 10.1371/journal.pone.0015518. [PMID: 21124737]
  • Christian Larrigaudière, Rosa Vilaplana, Inmaculada Recasens, Yolanda Soria, Eve Dupille. 'Diffuse skin browning' in 1-MCP-treated apples: etiology and systems of control. Journal of the science of food and agriculture. 2010 Nov; 90(14):2379-85. doi: 10.1002/jsfa.4094. [PMID: 20672331]
  • Qing Chang, Mark S Chapman, Jeffrey N Miner, David W Hedley. Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts. BMC cancer. 2010 Sep; 10(?):515. doi: 10.1186/1471-2407-10-515. [PMID: 20920162]
  • Imam A A Mekkawy, Usama M Mahmoud, Alaa G Osman, Alaa El-Din H Sayed. Effects of ultraviolet A on the activity of two metabolic enzymes, DNA damage and lipid peroxidation during early developmental stages of the African catfish, Clarias gariepinus (Burchell, 1822). Fish physiology and biochemistry. 2010 Sep; 36(3):605-626. doi: 10.1007/s10695-009-9334-6. [PMID: 19609701]
  • E Pitarch, T Portolés, J M Marín, M Ibáñez, F Albarrán, F Hernández. Analytical strategy based on the use of liquid chromatography and gas chromatography with triple-quadrupole and time-of-flight MS analyzers for investigating organic contaminants in wastewater. Analytical and bioanalytical chemistry. 2010 Aug; 397(7):2763-76. doi: 10.1007/s00216-010-3692-x. [PMID: 20428853]
  • Shuang-hong Song, Zhe-zhi Wang. Analysis of essential oils from different organs of Scutellaria baicalensis. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Aug; 33(8):1265-70. doi: ". [PMID: 21213540]
  • Ying C Henderson, Yunyun Chen, Mitchell J Frederick, Stephen Y Lai, Gary L Clayman. MEK inhibitor PD0325901 significantly reduces the growth of papillary thyroid carcinoma cells in vitro and in vivo. Molecular cancer therapeutics. 2010 Jul; 9(7):1968-76. doi: 10.1158/1535-7163.mct-10-0062. [PMID: 20587665]
  • Sheng-Jie Ni, Yi-Hua Qiu, Jian-Hua Lu, Bei-Bei Cao, Yu-Ping Peng. Effect of cerebellar fastigial nuclear lesions on differentiation and function of thymocytes. Journal of neuroimmunology. 2010 May; 222(1-2):40-7. doi: 10.1016/j.jneuroim.2010.02.017. [PMID: 20356634]
  • Joshua S Wiley, Juan F García-Reyes, Jason D Harper, Nicholas A Charipar, Zheng Ouyang, R Graham Cooks. Screening of agrochemicals in foodstuffs using low-temperature plasma (LTP) ambient ionization mass spectrometry. The Analyst. 2010 May; 135(5):971-9. doi: 10.1039/b919493b. [PMID: 20419245]
  • Eric B Haura, Alejandro D Ricart, Timothy G Larson, Philip J Stella, Lyudmila Bazhenova, Vincent A Miller, Roger B Cohen, Peter D Eisenberg, Paulina Selaru, Keith D Wilner, Shirish M Gadgeel. A phase II study of PD-0325901, an oral MEK inhibitor, in previously treated patients with advanced non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 Apr; 16(8):2450-7. doi: 10.1158/1078-0432.ccr-09-1920. [PMID: 20332327]
  • A M W Coppus, D Fekkes, W M A Verhoeven, S Tuinier, C M van Duijn. Plasma levels of nitric oxide related amino acids in demented subjects with Down syndrome are related to neopterin concentrations. Amino acids. 2010 Mar; 38(3):923-8. doi: 10.1007/s00726-009-0300-5. [PMID: 19455393]
  • Elida Bulku, Daniel Zinkovsky, Payal Patel, Vishal Javia, Tejas Lahoti, Inna Khodos, Sidney J Stohs, Sidhartha D Ray. A novel dietary supplement containing multiple phytochemicals and vitamins elevates hepatorenal and cardiac antioxidant enzymes in the absence of significant serum chemistry and genomic changes. Oxidative medicine and cellular longevity. 2010 Mar; 3(2):129-44. doi: 10.4161/oxim.3.2.11157. [PMID: 20716937]
  • Uwe Rauwolf, Hieronim Golczyk, Stephan Greiner, Reinhold G Herrmann. Variable amounts of DNA related to the size of chloroplasts III. Biochemical determinations of DNA amounts per organelle. Molecular genetics and genomics : MGG. 2010 Jan; 283(1):35-47. doi: 10.1007/s00438-009-0491-1. [PMID: 19911199]
  • Julius Leyton, Graham Smith, Yongjun Zhao, Meg Perumal, Quang-De Nguyen, Edward Robins, Erik Arstad, Eric O Aboagye. [18F]fluoromethyl-[1,2-2H4]-choline: a novel radiotracer for imaging choline metabolism in tumors by positron emission tomography. Cancer research. 2009 Oct; 69(19):7721-8. doi: 10.1158/0008-5472.can-09-1419. [PMID: 19773436]
  • C S Rejiya, T R Cibin, Annie Abraham. Leaves of Cassia tora as a novel cancer therapeutic--an in vitro study. Toxicology in vitro : an international journal published in association with BIBRA. 2009 Sep; 23(6):1034-8. doi: 10.1016/j.tiv.2009.06.010. [PMID: 19540331]
  • Manjula Shantaram, Anjali Rao, Annaya Rao Aroor, Annaswamy Raja, Suryanrayana Rao, Flama Monteiro. Assessment of total sialic acid and lipid-bound sialic acid in management of brain tumors. Annals of Indian Academy of Neurology. 2009 Jul; 12(3):162-6. doi: 10.4103/0972-2327.56315. [PMID: 20174496]