Adipostatin A (BioDeep_00000008333)

 

Secondary id: BioDeep_00000395521, BioDeep_00001874335

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


5-pentadecylbenzene-1,3-diol

  化学式: C21H36O2 (320.2715)
中文名称: 5-十五烷基间苯二酚, 5-十五烷基-1,3-苯二酚
  谱图信息: 最多检出来源 Homo sapiens(lipidomics) 20.83%

分子结构信息

SMILES: C1(O)C=C(CCCCCCCCCCCCCCC)C=C(O)C=1
InChI: InChI=1S/C21H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-16-20(22)18-21(23)17-19/h16-18,22-23H,2-15H2,1H3


描述信息

Isolated from cereals and other plants. Adipostatin A is found in many foods, some of which are hard wheat, rye, cereals and cereal products, and common wheat.
Adipostatin A is found in barley. Adipostatin A is isolated from cereals and other plant
5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti[1][2].
5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti[1][2].

同义名列表

10 个代谢物同义名

5-pentadecylbenzene-1,3-diol; 5-Pentadecyl-1,3-benzenediol; 5-n-pentadecylresorcinol; 5-Pentadecyl-resorcinol; 5-Pentadecylresorcinol; Adipostatin A; Cardol; PDR; 5-Pentadecylresorcinol; 5-Pentadecylresorcinol



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

101 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ACTB, ANXA5, CASP3, CASP9, GAPDH, MX1, MX2, PTGS1, PTGS2, TLR4, TYR, XDH
Peripheral membrane protein 5 ACHE, ANXA5, MX1, PTGS1, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 3 MX1, PTGS1, PTGS2
Nucleus 8 ACHE, ACTB, CASP3, CASP9, GAPDH, MX1, MX2, PARP1
cytosol 9 ACTB, ANXA5, CASP3, CASP9, GAPDH, MX1, MX2, PARP1, XDH
nuclear body 1 PARP1
nucleoplasm 3 ACTB, CASP3, PARP1
Cell membrane 2 ACHE, TLR4
lamellipodium 1 ACTB
Synapse 2 ACHE, ACTB
cell surface 3 ACHE, LBP, TLR4
glutamatergic synapse 2 ACTB, CASP3
Golgi apparatus 2 ACHE, PTGS1
Golgi membrane 1 INS
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 1 CASP3
sarcolemma 1 ANXA5
Cytoplasm, cytosol 2 GAPDH, PARP1
Lysosome 2 GAA, TYR
Presynapse 1 ACTB
plasma membrane 6 ACHE, ACTB, GAA, GAPDH, GCG, TLR4
Membrane 10 ACHE, ACTB, ANXA5, GAA, GAPDH, LBP, MX1, MX2, PARP1, TLR4
axon 1 ACTB
brush border 1 ACTB
caveola 1 PTGS2
extracellular exosome 7 ACTB, ANXA5, GAA, GAPDH, HP, LBP, PTGS1
Lysosome membrane 1 GAA
endoplasmic reticulum 1 PTGS2
extracellular space 7 ACHE, ACTB, GCG, HP, INS, LBP, XDH
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 5 ACHE, GAPDH, MX1, TLR4, TYR
Schaffer collateral - CA1 synapse 1 ACTB
adherens junction 1 ACTB
mitochondrion 2 CASP9, PARP1
protein-containing complex 4 ACTB, CASP9, PARP1, PTGS2
intracellular membrane-bounded organelle 4 GAA, GAPDH, PTGS1, TYR
Microsome membrane 2 PTGS1, PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 TLR4, TYR
Secreted 7 ACHE, GAA, GCG, HP, INS, LBP, PRB1
extracellular region 8 ACHE, ANXA5, GAA, GCG, HP, INS, LBP, PRB1
Extracellular side 1 ACHE
transcription regulator complex 1 PARP1
photoreceptor outer segment 1 PTGS1
nuclear membrane 2 GAPDH, MX1
external side of plasma membrane 2 ANXA5, TLR4
actin cytoskeleton 1 ACTB
microtubule cytoskeleton 1 GAPDH
nucleolus 1 PARP1
Melanosome membrane 1 TYR
Early endosome 1 TLR4
cell-cell junction 1 ACTB
Golgi-associated vesicle 1 TYR
vesicle 2 ACTB, GAPDH
Cytoplasm, perinuclear region 2 GAPDH, MX1
Cytoplasm, cytoskeleton 2 ACTB, GAPDH
focal adhesion 2 ACTB, ANXA5
microtubule 2 MX1, MX2
Peroxisome 1 XDH
basement membrane 1 ACHE
sarcoplasmic reticulum 1 XDH
collagen-containing extracellular matrix 1 ANXA5
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
Zymogen granule membrane 1 ANXA5
neuron projection 2 PTGS1, PTGS2
chromatin 2 ACTB, PARP1
phagocytic cup 1 TLR4
Chromosome 1 PARP1
cytoskeleton 2 ACTB, GAPDH
cytoplasmic ribonucleoprotein granule 1 ACTB
Nucleus, nucleolus 1 PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
actin filament 1 ACTB
blood microparticle 2 ACTB, HP
NuA4 histone acetyltransferase complex 1 ACTB
Lipid-anchor, GPI-anchor 1 ACHE
site of double-strand break 1 PARP1
Nucleus, nuclear pore complex 1 MX2
nuclear envelope 1 PARP1
nuclear pore 1 MX2
Endomembrane system 1 PTGS1
endosome lumen 1 INS
Lipid droplet 1 GAPDH
tertiary granule membrane 1 GAA
Melanosome 1 TYR
side of membrane 1 ACHE
lipopolysaccharide receptor complex 1 TLR4
secretory granule lumen 2 GCG, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 GCG, INS, PTGS2
nuclear matrix 1 ACTB
specific granule lumen 1 HP
tertiary granule lumen 1 HP
kinetochore 1 ACTB
transport vesicle 1 INS
azurophil granule membrane 1 GAA
tight junction 1 ACTB
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
bBAF complex 1 ACTB
brahma complex 1 ACTB
nBAF complex 1 ACTB
npBAF complex 1 ACTB
SWI/SNF complex 1 ACTB
apoptosome 1 CASP9
[Isoform 2]: Cytoplasm 1 MX1
calyx of Held 1 ACTB
vesicle membrane 1 ANXA5
ribonucleoprotein complex 2 ACTB, GAPDH
synaptic cleft 1 ACHE
protein-DNA complex 1 PARP1
ficolin-1-rich granule membrane 1 GAA
death-inducing signaling complex 1 CASP3
apical junction complex 1 ACTB
nucleosome 1 ACTB
postsynaptic actin cytoskeleton 1 ACTB
GAIT complex 1 GAPDH
site of DNA damage 1 PARP1
GBAF complex 1 ACTB
RSC-type complex 1 ACTB
endocytic vesicle lumen 1 HP
haptoglobin-hemoglobin complex 1 HP
[Glucagon-like peptide 1]: Secreted 1 GCG
cortical cytoskeleton 1 ACTB
endothelial microparticle 1 ANXA5
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
autolysosome lumen 1 GAA
Cytoplasmic granule membrane 1 LBP
[Isoform H]: Cell membrane 1 ACHE
caspase complex 1 CASP9
dense body 1 ACTB


文献列表

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