chlorophorin (BioDeep_00000007968)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


2,4,3,5-tetrahydroxy-4(3,7-di-methyl-2,6-octadienyl)-stilbene

化学式: C24H28O4 (380.1987)
中文名称: 高黄绿酸
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 83.7%

分子结构信息

SMILES: C1(C/C=C(\C)/CC/C=C(\C)/C)=C(O)C=C(/C=C/C2=CC=C(O)C=C2O)C=C1O
InChI: InChI=1S/C24H28O4/c1-16(2)5-4-6-17(3)7-12-21-23(27)13-18(14-24(21)28)8-9-19-10-11-20(25)15-22(19)26/h5,7-11,13-15,25-28H,4,6,12H2,1-3H3/b9-8+,17-7+

描述信息

同义名列表

3 个代谢物同义名

chlorophorin; 2,4,3,5-tetrahydroxy-4(3,7-di-methyl-2,6-octadienyl)-stilbene; Chlorophorin



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

25 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 APOB, GAPDH, GGPS1, POMC, RHOA, TYR
Peripheral membrane protein 2 CYP1B1, PRTN3
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 6 ABCA1, APOB, CYP1A2, CYP1B1, HSP90B1, RHOA
Nucleus 4 GAPDH, HSP90B1, PLCZ1, RHOA
cytosol 9 APOB, GAPDH, GGPS1, HBB, HSP90B1, PDPN, PLCZ1, PRTN3, RHOA
phagocytic vesicle 1 ABCA1
nucleoplasm 3 ATP2B1, GGPS1, PLCZ1
Cell membrane 4 ABCA1, ATP2B1, PRTN3, RHOA
Lipid-anchor 1 RHOA
Cytoplasmic side 1 RHOA
Cleavage furrow 1 RHOA
lamellipodium 2 PDPN, RHOA
ruffle membrane 2 PDPN, RHOA
Cytoplasmic granule 1 PRTN3
Multi-pass membrane protein 2 ABCA1, ATP2B1
Synapse 1 ATP2B1
cell cortex 1 RHOA
cell junction 2 PDPN, RHOA
cell surface 1 TNR
glutamatergic synapse 3 ATP2B1, RHOA, TNR
Golgi apparatus 1 ABCA1
mitochondrial inner membrane 1 FECH
neuronal cell body 1 APOB
postsynapse 1 RHOA
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 2 APOB, HSP90B1
Cytoplasm, cytosol 1 GAPDH
Lysosome 1 TYR
endosome 2 ABCA1, RHOA
plasma membrane 8 ABCA1, APOB, ATP2B1, BCHE, GAPDH, PDPN, PRTN3, RHOA
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ABCA1, ATP2B1, CYP1B1, GAPDH, HBB, HSP90B1, PDPN
apical plasma membrane 1 PDPN
basolateral plasma membrane 3 ABCA1, ATP2B1, PDPN
extracellular exosome 7 APOB, ATP2B1, GAPDH, HBB, HSP90B1, PRTN3, RHOA
endoplasmic reticulum 1 HSP90B1
extracellular space 6 APOB, BCHE, HBB, POMC, PRTN3, TNR
lysosomal lumen 1 APOB
perinuclear region of cytoplasm 6 ABCA1, GAPDH, GGPS1, HSP90B1, PLCZ1, TYR
Schaffer collateral - CA1 synapse 1 TNR
mitochondrion 3 CYP1B1, FECH, PDPN
protein-containing complex 1 HSP90B1
intracellular membrane-bounded organelle 8 ABCA1, APOB, ATP2B1, CYP1A2, CYP1B1, GAPDH, PRTN3, TYR
Microsome membrane 2 CYP1A2, CYP1B1
filopodium 1 PDPN
pronucleus 1 PLCZ1
Single-pass type I membrane protein 2 PDPN, TYR
Secreted 4 APOB, BCHE, POMC, PRTN3
extracellular region 7 APOB, BCHE, HBB, HSP90B1, POMC, PRTN3, TNR
cytoplasmic side of plasma membrane 1 RHOA
mitochondrial matrix 1 FECH
Extracellular side 1 PRTN3
anchoring junction 1 PDPN
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 GAPDH
external side of plasma membrane 1 ABCA1
Secreted, extracellular space, extracellular matrix 1 TNR
chylomicron 1 APOB
low-density lipoprotein particle 1 APOB
very-low-density lipoprotein particle 1 APOB
dendritic spine 1 RHOA
Z disc 1 GGPS1
cytoplasmic vesicle 1 PDPN
microtubule cytoskeleton 1 GAPDH
nucleolus 1 PLCZ1
Melanosome membrane 1 TYR
midbody 2 HSP90B1, RHOA
Early endosome 1 APOB
Golgi-associated vesicle 1 TYR
vesicle 2 GAPDH, RHOA
Apical cell membrane 1 PDPN
Cell projection, lamellipodium 1 RHOA
Cell projection, ruffle membrane 1 PDPN
Cytoplasm, perinuclear region 3 GAPDH, GGPS1, PLCZ1
Mitochondrion inner membrane 1 FECH
Membrane raft 4 ABCA1, PDPN, PRTN3, TNR
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 2 HSP90B1, RHOA
intracellular vesicle 1 ABCA1
collagen-containing extracellular matrix 2 HSP90B1, TNR
secretory granule 1 POMC
lateral plasma membrane 1 ATP2B1
ruffle 1 PDPN
cell projection 2 ATP2B1, PDPN
cell periphery 1 RHOA
cytoskeleton 2 GAPDH, RHOA
Cytoplasm, cell cortex 1 RHOA
blood microparticle 2 BCHE, HBB
Basolateral cell membrane 2 ATP2B1, PDPN
Cell projection, microvillus membrane 1 PDPN
microvillus membrane 1 PDPN
endosome lumen 1 APOB
Lipid droplet 2 APOB, GAPDH
Cell projection, dendrite 1 RHOA
Melanosome 2 HSP90B1, TYR
Presynaptic cell membrane 1 ATP2B1
sperm plasma membrane 1 HSP90B1
filopodium membrane 1 PDPN
Cytoplasm, myofibril, sarcomere, Z line 1 GGPS1
plasma membrane raft 1 PRTN3
ficolin-1-rich granule lumen 1 HBB
secretory granule lumen 1 POMC
secretory granule membrane 1 RHOA
endoplasmic reticulum lumen 3 APOB, BCHE, HSP90B1
tertiary granule lumen 1 HBB
endocytic vesicle 1 ABCA1
azurophil granule lumen 1 PRTN3
endoplasmic reticulum exit site 1 APOB
immunological synapse 1 ATP2B1
perineuronal net 1 TNR
tetraspanin-enriched microdomain 1 PDPN
nuclear envelope lumen 1 BCHE
clathrin-coated endocytic vesicle membrane 1 APOB
Sarcoplasmic reticulum lumen 1 HSP90B1
ribonucleoprotein complex 1 GAPDH
ficolin-1-rich granule membrane 1 RHOA
apical junction complex 1 RHOA
GAIT complex 1 GAPDH
Cell projection, filopodium membrane 1 PDPN
lamellipodium membrane 1 PDPN
hemoglobin complex 1 HBB
endocytic vesicle lumen 3 APOB, HBB, HSP90B1
haptoglobin-hemoglobin complex 1 HBB
chylomicron remnant 1 APOB
intermediate-density lipoprotein particle 1 APOB
sperm head 1 PLCZ1
mature chylomicron 1 APOB
Cell projection, lamellipodium membrane 1 PDPN
endoplasmic reticulum chaperone complex 1 HSP90B1
photoreceptor ribbon synapse 1 ATP2B1
tenascin complex 1 TNR
Cell projection, invadopodium 1 PDPN
[Podoplanin]: Membrane 1 PDPN
[29kDa cytosolic podoplanin intracellular domain]: Cytoplasm, cytosol 1 PDPN
leading edge of lamellipodium 1 PDPN


文献列表

  • Enos Tangke Arung, Kuniyoshi Shimizu, Ryuichiro Kondo. Artocarpus plants as a potential source of skin whitening agents. Natural product communications. 2011 Sep; 6(9):1397-402. doi: . [PMID: 21941923]
  • Victor S Sobolev, Shabana I Khan, Nurhayat Tabanca, David E Wedge, Susan P Manly, Stephen J Cutler, Monique R Coy, James J Becnel, Scott A Neff, James B Gloer. Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids. Journal of agricultural and food chemistry. 2011 Mar; 59(5):1673-82. doi: 10.1021/jf104742n. [PMID: 21314127]
  • S Beekrum, R Govinden, T Padayachee, B Odhav. Naturally occurring phenols: a detoxification strategy for fumonisin B1. Food additives and contaminants. 2003 May; 20(5):490-3. doi: 10.1080/0265203031000098678. [PMID: 12775468]
  • Kuniyoshi Shimizu, Seiji Yasutake, Ryuichiro Kondo. A new stilbene with tyrosinase inhibitory activity from Chlorophora excelsa. Chemical & pharmaceutical bulletin. 2003 Mar; 51(3):318-9. doi: 10.1248/cpb.51.318. [PMID: 12612420]
  • T Padayachee, B Odhav. Anti-amoebic activity of plant compounds from Virgilia oroboides and Chlorophora excelsa. Journal of ethnopharmacology. 2001 Nov; 78(1):59-66. doi: 10.1016/s0378-8741(01)00325-7. [PMID: 11585689]
  • L Kanerva, T Estlander, K Alanko, R Jolanki. Patch test sensitization to Compositae mix, sesquiterpene-lactone mix, Compositae extracts, laurel leaf, Chlorophorin, Mansonone A, and dimethoxydalbergione. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society. 2001 Mar; 12(1):18-24. doi: 10.1053/ajcd.2000.9547. [PMID: 11244135]