Galegine (BioDeep_00000006715)
PANOMIX_OTCML-2023
代谢物信息卡片
Galegine
化学式: C6H13N3 (127.1109)
中文名称: 2-(3-甲基丁2-Enyl)胍
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 90.18%
分子结构信息
SMILES: CC(=CCN=C(N)N)C
InChI: InChI=1S/C6H13N3/c1-5(2)3-4-9-6(7)8/h3H,4H2,1-2H3,(H4,7,8,9)
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:5265
- KEGG: C08303
- PubChem: 10983
- Metlin: METLIN66896
- ChEMBL: CHEMBL111469
- CAS: 543-83-9
- PMhub: MS000054506
- PMhub: MS000019814
- PubChem: 10501
- KNApSAcK: C00001410
- NIKKAJI: J78.499K
- RefMet: Galegine
- KNApSAcK: 5265
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 754879 - Galega lindblomii: 10.1016/S0305-1978(02)00224-7
- 47101 - Galega officinalis:
- 47654 - Galega orientalis: 10.2307/4117899
- 162890 - Pterogyne nitens: 10.1021/NP800612X
- 945253 - Verbesina encelioides:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mohammad Behrouzi Varjovi, Rasool Asghari Zakaria, Sadegh Rostamnia, Behnam Gholipour. Biosynthesized Ag nanoparticles on urea-based periodic mesoporous organosilica enhance galegine content in Galega.
Applied microbiology and biotechnology.
2023 Feb; ?(?):. doi:
10.1007/s00253-023-12414-6. [PMID: 36738339] - Traci E LaMoia, Gina M Butrico, Hasini A Kalpage, Leigh Goedeke, Brandon T Hubbard, Daniel F Vatner, Rafael C Gaspar, Xian-Man Zhang, Gary W Cline, Keita Nakahara, Seungwan Woo, Atsuhiro Shimada, Maik Hüttemann, Gerald I Shulman. Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
Proceedings of the National Academy of Sciences of the United States of America.
2022 03; 119(10):e2122287119. doi:
10.1073/pnas.2122287119. [PMID: 35238637] - Weien Wang, Xiaofeng Zhang. Antihypertensive Effect of Galegine from Biebersteinia heterostemon in Rats.
Molecules (Basel, Switzerland).
2021 Aug; 26(16):. doi:
10.3390/molecules26164830. [PMID: 34443434] - Luis Octávio Regasini, Ian Castro-Gamboa, Dulce Helena Siqueira Silva, Maysa Furlan, Eliezer Jesus Barreiro, Paulo Michel Pinheiro Ferreira, Cláudia Pessoa, Letícia Veras Costa Lotufo, Manoel Odorico de Moraes, Maria Claudia Marx Young, Vanderlan da Silva Bolzani. Cytotoxic guanidine alkaloids from Pterogyne nitens.
Journal of natural products.
2009 Mar; 72(3):473-6. doi:
10.1021/np800612x. [PMID: 19159272] - M H Mooney, S Fogarty, C Stevenson, A M Gallagher, P Palit, S A Hawley, D G Hardie, G D Coxon, R D Waigh, R J Tate, A L Harvey, B L Furman. Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice.
British journal of pharmacology.
2008 Apr; 153(8):1669-77. doi:
10.1038/bjp.2008.37. [PMID: 18297106] - Hai-Feng Wu, Xiao-Feng Zhang, Ye Deng, Li Pan, Li-Sheng Ding. [Studies on chemical constituents from bark of Biebersteinia heterostemon].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2007 Oct; 32(20):2141-3. doi:
. [PMID: 18306747] - Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2005 Jul; 46(1):e11-4. doi:
10.1053/j.ajkd.2005.03.009. [PMID: 15983949] - A T Atanasov, V Spasov. Inhibiting effect of desalted extract from Galega officinalis L. on platelet aggregation.
Folia medica.
1999; 41(1):46-50. doi:
NULL. [PMID: 10462920] - T A Lopez, C M Campero, R Chayer, B Cosentino, M Caracino. Experimental toxicity of verbesina encelioides in sheep and isolation of galegine.
Veterinary and human toxicology.
1996 Dec; 38(6):417-9. doi:
. [PMID: 8948070] - C R Huxtable, P R Dorling, S M Colegate. Identification of galegine, an isoprenyl guanidine, as the toxic principle of Schoenus asperocarpus (poison sedge).
Australian veterinary journal.
1993 May; 70(5):169-71. doi:
10.1111/j.1751-0813.1993.tb06120.x. [PMID: 8343085] - R F Keeler, D C Baker, K E Panter. Concentration of galegine in Verbesina encelioides and Galega oficinalis and the toxic and pathologic effects induced by the plants.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
1992 Mar; 11(2):11-7. doi:
. [PMID: 1573558] - S Tsuji, K Nakagawa, T Fukushima. Genetically controlled quantitative variation of ornithine transcarbamylase in the chick kidney.
Biochemical genetics.
1983 Oct; 21(9-10):857-69. doi:
10.1007/bf00483945. [PMID: 6419722] - H H Borden, R W Harris, W E Mosher. A waterborne outbreak of gastroenteritis in western New York State.
American journal of public health and the nation's health.
1970 Feb; 60(2):283-8. doi:
10.2105/ajph.60.2.283. [PMID: 5460971]
