Busulfan (BioDeep_00000006359)
Secondary id: BioDeep_00000398780
human metabolite blood metabolite
代谢物信息卡片
4-(methanesulfonyloxy)butyl methanesulfonate
化学式: C6H14O6S2 (246.0231784)
中文名称: 白消安
谱图信息:
最多检出来源 Homo sapiens(blood) 69.86%
Reviewed
Last reviewed on 2024-10-31.
Cite this Page
Busulfan. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/busulfan (retrieved
2024-11-08) (BioDeep RN: BioDeep_00000006359). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CS(=O)(=O)OCCCCOS(=O)(=O)C
InChI: InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3
描述信息
An alkylating agent having a selective immunosuppressive effect on bone marrow. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen. [PubChem]
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AB - Alkyl sulfonates
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D000970 - Antineoplastic Agents > D019653 - Myeloablative Agonists
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
D009676 - Noxae > D000477 - Alkylating Agents
同义名列表
52 个代谢物同义名
4-(methanesulfonyloxy)butyl methanesulfonate; Tetramethylenester kyseliny methansulfonove; Tetramethylene bis(methanesulphonic acid); Tetramethylene bis(methanesulfonic acid); 1,4-Butanediol dimethanesulphonic acid; Tetramethylene bis(methanesulphonate); 1,4-Butanediol dimethanesulfonic acid; Tetramethylene bis(methanesulfonate); Tetramethylene dimethane sulfonate; 1,4-Butanediol dimethanesulphonate; GlaxoSmithKline brand OF busulfan; 1,4-Butanediol dimethanesulfonate; Glaxo wellcome brand OF busulfan; 1,4-Bis(methanesulphonoxy)butane; N-Butane-1,3-di(methylsulfonate); 1,4-Bis(methanesulfonoxy)butane; Busulfan glaxosmithkline brand; 1,4-Dimethanesulphonoxybutane; 1,4-Dimethanesulfonoxybutane; Butanedioldimethanesulfonate; Wellcome brand OF busulfan; Orphan brand OF busulfan; Busulfan wellcome brand; Busulfan orphan brand; 1,4-Dimesyloxybutane; Wellcome, busulfan; Busulfan wellcome; Leucosulphan; Myeloleukon; Busulphanum; Sulphabutin; Leucosulfan; Busulphano; Busulfanum; Sulfabutin; Busulphane; Glyzophrol; Bisulphex; Busulfano; Busulphan; Mylecytan; Bisulfex; Misulban; busulfan; Buzulfan; Busulfex; Mielucin; Myelosan; Mitostan; Myléran; Myleran; Mablin
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:28901
- KEGG: C06862
- KEGGdrug: D00248
- KEGGdrug: D88731
- PubChem: 2478
- HMDB: HMDB0015143
- Metlin: METLIN546
- DrugBank: DB01008
- ChEMBL: CHEMBL820
- Wikipedia: Busulfan
- MeSH: Busulfan
- chemspider: 2384
- CAS: 55-98-1
- PMhub: MS000019387
- PubChem: 9080
- RefMet: Busulfan
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jiacheng Lin, Jun Wang, Chenghui Wang, Yuetong Shan, Wei Jing, Zhimin Fei, Weidong Pan. Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 1: Biogenic components and identification of targets and signaling pathways in amyotrophic lateral sclerosis patients.
International journal of clinical pharmacology and therapeutics.
2024 Apr; 62(4):155-161. doi:
10.5414/cp204501. [PMID: 38239147] - Jun Jing, Lei Ouyang, Hong Zhang, Kuan Liang, Rujun Ma, Xie Ge, Ting Tang, Shanmeizi Zhao, Tongmin Xue, Jiaming Shen, Jinzhao Ma, Zhou Li, Jing Wu, Yang Yang, Wei Zhao, Lu Zheng, Zhang Qian, Shanshan Sun, Yifeng Ge, Li Chen, Chaojun Li, Bing Yao. Omega-3 polyunsaturated fatty acids and its metabolite 12-HEPE rescue busulfan disrupted spermatogenesis via target to GPR120.
Cell proliferation.
2023 Sep; ?(?):e13551. doi:
10.1111/cpr.13551. [PMID: 37743695] - Julien Allard, Simon Bucher, Pierre-Jean Ferron, Youenn Launay, Bernard Fromenty. Busulfan induces steatosis in HepaRG cells but not in primary human hepatocytes: Possible explanations and implication for the prediction of drug-induced liver injury.
Fundamental & clinical pharmacology.
2023 Sep; ?(?):. doi:
10.1111/fcp.12951. [PMID: 37665028] - H X Liu, D L Wei, S Shao, Y Jiang, S Li, J Zhu, C Wang, C X Zhao. [Impact of immunosuppression intensified conditioning regimen for patients with strong positive pre-transplantation donor-specific anti-HLA antibodies (DSAs) undergoing haploidentical hematopoietic stem cell transplantation].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi.
2023 Aug; 44(8):654-659. doi:
10.3760/cma.j.issn.0253-2727.2023.08.007. [PMID: 37803839] - Xiaoyan Li, Haifeng Ye, Tie Su, Chuan Hu, Yaoqi Huang, Xinxin Fu, Zhisheng Zhong, Xuelian Du, Yuehui Zheng. Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model mice.
Frontiers in immunology.
2023; 14(?):1185921. doi:
10.3389/fimmu.2023.1185921. [PMID: 37228612] - Juju Shang, Shenglei Qiu, Yingjie Zhou, Sina Liu, Zi Wang, Xiaolei Lai, Hongxu Liu, Mingxue Zhou, Zhenmin Zhang, Pengyu Liu, Fangfang Zhang, Xianghui Meng. Efficacy and safety of Tonifying Qi and activating blood Chinese herbal prescriptions for myocardial infarction: Study protocol for a multi-centered RCT.
Medicine.
2022 Nov; 101(47):e31680. doi:
10.1097/md.0000000000031680. [PMID: 36451469] - Zi-Zhao Yang, Xiao-Long Wang, Di Zhang, Shuai Ma, Lian-Wen Zheng. [Therapeutic effect of Heirong Kidney-Tonifying Granule on busulfan-induced dyszoospermia in model mice].
Zhonghua nan ke xue = National journal of andrology.
2022 Nov; 28(11):1031-1037. doi:
. [PMID: 37846121] - Amirabbas Rostami, Sina Vakili, Farhad Koohpeyma, Bahia Namavar Jahromi, Ziba Afshari Aghajari, Fatemeh Mahmoudikohani, Forough Saki, Marzieh Mahmoodi, Khojaste Rahimi Jaberi, Ahmad Movahedpour, Majid Jafari Khorchani, Saam Noroozi. Ellagic acid effects on testis, sex hormones, oxidative stress, and apoptosis in the relative sterility rat model following busulfan administration.
BMC complementary medicine and therapies.
2022 Jun; 22(1):170. doi:
10.1186/s12906-022-03650-w. [PMID: 35739528] - Haolong Liu, Yiyi Zhao, Qi Zheng, Tao Yang, Hui Zhao, Haiyan Zou, Yongping Fan, Hongzhu Guo, Lei Wang. Identification and Quantification of Bu Shen Yi Sui Capsule by UPLC-LTQ-Orbitrap-MSn and UPLC-QTOF-MS/MS.
Journal of chromatographic science.
2022 Jun; 60(5):450-457. doi:
10.1093/chromsci/bmab091. [PMID: 34286839] - Sunny O Abarikwu, Chidimma J Mgbudom-Okah, Chigozie L Onuah. The protective effect of rutin against busulfan-induced testicular damage in adult rats.
Drug and chemical toxicology.
2022 May; 45(3):1035-1043. doi:
10.1080/01480545.2020.1803905. [PMID: 32757678] - Edesiri P Tesi, Benneth Ben-Azu, Oyovwi O Mega, Joseph Mordi, Obed O Knowledge, Egbuchua D Awele, Rume A Rotu, Victor Emojevwe, Olusegun G Adebayo, Okubo Aya-Ebi Eneni. Kolaviron, a flavonoid-rich extract ameliorates busulfan-induced chemo-brain and testicular damage in male rats through inhibition of oxidative stress, inflammatory, and apoptotic pathways.
Journal of food biochemistry.
2022 04; 46(4):e14071. doi:
10.1111/jfbc.14071. [PMID: 35060131] - Stephan Schaller, Frederico S Martins, Pavel Balazki, Sonja Böhm, Joachim Baumgart, Ralf A Hilger, Dietrich W Beelen, Claudia Hemmelmann, Arne Ring. Evaluation of the drug-drug interaction potential of treosulfan using a physiologically-based pharmacokinetic modelling approach.
British journal of clinical pharmacology.
2022 02; 88(4):1722-1734. doi:
10.1111/bcp.15081. [PMID: 34519068] - S O Abarikwu, C J Mgbudom-Okah, C L Onuah, A Ogunlaja. Fluted pumpkin seeds protect against busulfan-induced oxidative stress and testicular injuries in adult mice.
Drug and chemical toxicology.
2022 Jan; 45(1):22-32. doi:
10.1080/01480545.2019.1657885. [PMID: 31469002] - Shifen Fan, Jiao Chen, Zhouyang Liu, Juan Xiao, Fan Jiang, Xiaomei Liu, Yuan Sun. Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation with Cocktail Conditioning Regimen for the Treatment of Pediatric Patients with Chronic Active Epstein-Barr Virus: A Retrospective Observational Study.
Stem cells and development.
2022 01; 31(1-2):26-31. doi:
10.1089/scd.2021.0205. [PMID: 34779276] - Mary Rose Hilaire, Regina V Gill, Jodi B Courtney, Irina Baburina, JoAnn Gardiner, Michael C Milone, Leslie M Shaw, Qing H Meng, Salvatore J Salamone. Evaluation of a Nanoparticle-Based Busulfan Immunoassay for Rapid Analysis on Routine Clinical Analyzers.
Therapeutic drug monitoring.
2021 12; 43(6):766-771. doi:
10.1097/ftd.0000000000000883. [PMID: 33814542] - Fatereh Rezaei, Mohammad Bayat, Hamid Nazarian, Abbas Aliaghaei, Hojjat-Allah Abaszadeh, Parvaneh Naserzadeh, Abdollah Amini, Vahid Ebrahimi, Shabnam Abdi, Mohammad-Amin Abdollahifar. Photobiomodulation Therapy Improves Spermatogenesis in Busulfan-Induced Infertile Mouse.
Reproductive sciences (Thousand Oaks, Calif.).
2021 10; 28(10):2789-2798. doi:
10.1007/s43032-021-00557-8. [PMID: 33825170] - Jeannine S McCune, Arjen M Punt, Rosa F Yeh, L Lee Dupuis, Dina M Kweekel, Eric J F Franssen, James C Ritchie, Erik van Maarseveen, Alwin D R Huitema. Quality Control of Busulfan Plasma Quantitation, Modeling, and Dosing: An Interlaboratory Proficiency Testing Program.
Therapeutic drug monitoring.
2021 10; 43(5):657-663. doi:
10.1097/ftd.0000000000000862. [PMID: 33675302] - E Neroutsos, I Athanasiadou, A Paisiou, K Zisaki, E Goussetis, H Archontaki, P Tsirigotis, M Kitra, S Grafakos, A Spyridonidis, A Dokoumetzidis, G Valsami. Dose individualization of intravenous busulfan in pediatric patients undergoing bone marrow transplantation: impact and in vitro evaluation of infusion lag-time.
The Journal of pharmacy and pharmacology.
2021 Sep; 73(10):1340-1350. doi:
10.1093/jpp/rgab087. [PMID: 34244783] - Anders Mikal Andersen, Stein Bergan, Tobias Gedde-Dahl, Jochen Buechner, Nils Tore Vethe. Fast and reliable quantification of busulfan in blood plasma using two-channel liquid chromatography tandem mass spectrometry: Validation of assay performance in the presence of drug formulation excipients.
Journal of pharmaceutical and biomedical analysis.
2021 Sep; 203(?):114216. doi:
10.1016/j.jpba.2021.114216. [PMID: 34182411] - Tomoyuki Utano, Motohiro Kato, Kenichi Sakamoto, Tomoo Osumi, Kana Matsumoto, Daisuke Tomizawa, Kimikazu Matsumoto, Akimasa Yamatani. Two-point blood sampling is sufficient and necessary to estimate the area under the concentration-time curve for intravenous busulfan in infants and young children.
Pediatric blood & cancer.
2021 08; 68(8):e29069. doi:
10.1002/pbc.29069. [PMID: 33881202] - Fabiana C N Granzotto, Anne C C da Silva, Lilian F Lizot, Marina V Antunes, Rafael Linden. Dried Plasma Spots and Oral Fluid as Alternative Matrices for Therapeutic Drug Monitoring of Busulfan: Analytical Method Development and Clinical Evaluation.
Therapeutic drug monitoring.
2021 06; 43(3):376-385. doi:
10.1097/ftd.0000000000000807. [PMID: 32960547] - Dongyuan Tang, Xiushan Feng, Li Ling, Wenqian Zhang, Yanjing Luo, Yaping Wang, Zhengai Xiong. Experimental study for the establishment of a chemotherapy-induced ovarian insufficiency model in rats by using cyclophosphamide combined with busulfan.
Regulatory toxicology and pharmacology : RTP.
2021 Jun; 122(?):104915. doi:
10.1016/j.yrtph.2021.104915. [PMID: 33705838] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Ahmed El-Serafi, Rui He, Wenyi Zheng, Fadwa Benkossou, Sandra Oerther, Ying Zhao, Karin Mellgren, Britt Gustafsson, Carsten Heilmann, Jukka Kanerva, Kourosh Lotfi, Jacek Toporski, Mikael Sundin, Martin Höglund, Jonas Mattsson, Ibrahim El-Serafi, Moustapha Hassan. Vitamin D levels and busulphan kinetics in patients undergoing hematopoietic stem cell transplantation, a multicenter study.
Bone marrow transplantation.
2021 04; 56(4):807-817. doi:
10.1038/s41409-020-01091-y. [PMID: 33087877] - Taku Kikuchi, Takehiko Mori, Chikako Ohwada, Masahiro Onoda, Hiroaki Shimizu, Hiroki Yokoyama, Makoto Onizuka, Yuya Koda, Jun Kato, Yusuke Takeda, Yutaro Hino, Tatsuzo Mishina, Emiko Sakaida, Katsuhiro Shono, Yuhei Nagao, Akira Yokota, Kana Matsumoto, Kunihiko Morita, Shinichiro Okamoto. Pharmacokinetics of intravenous busulfan as condition for hematopoietic stem cell transplantation: comparison between combinations with cyclophosphamide and fludarabine.
International journal of hematology.
2021 Jan; 113(1):128-133. doi:
10.1007/s12185-020-02990-y. [PMID: 32886279] - Jeannine S McCune, Jožefa S McKiernan, Erik van Maarseveen, Alwin D R Huitema, Timothy W Randolph, H Joachim Deeg, Ryotaro Nakamura, K Scott Baker. Prediction of Acute Graft versus Host Disease and Relapse by Endogenous Metabolomic Compounds in Patients Receiving Personalized Busulfan-Based Conditioning.
Journal of proteome research.
2021 01; 20(1):684-694. doi:
10.1021/acs.jproteome.0c00599. [PMID: 33064008] - Simona De Gregori, Carmine Tinelli, Federica Manzoni, Antonella Bartoli. Comparison of Two Analytical Methods for Busulfan Therapeutic Drug Monitoring.
European journal of drug metabolism and pharmacokinetics.
2021 Jan; 46(1):155-159. doi:
10.1007/s13318-020-00660-2. [PMID: 33231835] - Iracema Esteves, Fabio Pires Souza Santos, Andreza Alice Feitosa Ribeiro, Adriana Seber, Eduardo Kinio Sugawara, Jairo José do Nascimento Sobrinho, José Carlos Barros, José Salvador Rodrigues Oliveira, Juliana Folloni Fernandes, Nelson Hamerschlak, Borje S Andersson, Marcos de Lima, Fabio Rodrigues Kerbauy. Targeted-dose of busulfan: Higher risk of sinusoidal obstructive syndrome observed with systemic exposure dose above 5000 µMol⸱min. A historically controlled clinical trial.
Hematological oncology.
2020 Dec; 38(5):773-781. doi:
10.1002/hon.2789. [PMID: 32779746] - Mohammad-Amin Abdollahifar, Vahid Ebrahimi, Abbas Aliaghaei, Amir Raoofi, Amirreza Khosravi, Amirhosein Hasani, Ali Mehdizadeh, Mohammad Asadi. Protective effect of curcumin on busulfan-induced renal toxicity in male rats.
Renal failure.
2020 Nov; 42(1):969-977. doi:
10.1080/0886022x.2020.1818580. [PMID: 32954910] - Dorota Danielak, Michał Romański, Anna Kasprzyk, Artur Teżyk, Franciszek Główka. Population pharmacokinetic approach for evaluation of treosulfan and its active monoepoxide disposition in plasma and brain on the basis of a rat model.
Pharmacological reports : PR.
2020 Oct; 72(5):1297-1309. doi:
10.1007/s43440-020-00115-0. [PMID: 32474888] - Alison Leiper, Maite Houwing, E Graham Davies, Kanchan Rao, Siobhan Burns, Emma Morris, Joop Laven, Anne-Lotte van der Kooi, Marry van den Heuvel Eibrink, Stephen Nussey. Anti-Müllerian hormone and Inhibin B after stem cell transplant in childhood: a comparison of myeloablative, reduced intensity and treosulfan-based chemotherapy regimens.
Bone marrow transplantation.
2020 10; 55(10):1985-1995. doi:
10.1038/s41409-020-0866-9. [PMID: 32231250] - Stalin Ramprakash, C P Raghuram, Priya Marwah, Rajpreet Soni, Deepa Trivedi, Sadaf Khalid, Naila Yaqub, Fatima Itrat, Sarah Khan Gilani, Tatheer Zahra, Rakesh Dhanya, Rajat Kumar Agarwal, Lawrence Faulkner. Splenomegaly May Increase the Risk of Rejection in Low-Risk Matched Related Donor Transplant for Thalassemia, This Risk Can Be Partially Overcome by Additional Immunosuppression during Conditioning.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2020 10; 26(10):1886-1893. doi:
10.1016/j.bbmt.2020.06.013. [PMID: 32592858] - Yuan Jinjie, Ning Sun, Shuyu Zhang, Xinying Feng, Xijing Chen, Di Zhao, Libo Zhao. A rapid HPLC-MS/MS method for determining busulfan in hemolytic samples from children with hematopoietic stem cell transplantation.
Biomedical chromatography : BMC.
2020 Sep; 34(9):e4898. doi:
10.1002/bmc.4898. [PMID: 32428257] - L Lee Dupuis, Christine M Quinones, James Ritchie, Paul A Carpenter, Tiene Bauters, Rosa F Yeh, Claudio Anasetti, Jaap J Boelens, Nelson Hamerschlak, Moustapha Hassan, Hyoung Jin Kang, Yoshinobu Kanda, Angelo Paci, Miguel-Angel Perales, Peter J Shaw, Victoria L Seewaldt, Bipin N Savani, Olga Militano, Michael A Pulsipher, Jeannine S McCune. Response to Kawedia et al Letter to Editor in Response to the Article by McCune Et Al 'Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement'.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2020 09; 26(9):e235-e236. doi:
10.1016/j.bbmt.2020.06.001. [PMID: 32531439] - Jitesh D Kawedia, Victoria W Handy, Terri Lynn Shigle, Alison M Gulbis, Yago Nieto, Borje S Andersson. Letter to the Editor Regarding 'Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement'.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2020 09; 26(9):e232-e234. doi:
10.1016/j.bbmt.2020.03.022. [PMID: 32407883] - Fernanda de Paula Eduardo, Letícia Mello Bezinelli, Danielle L C Carvalho, Mariana Henriques Ferreira, Marcella Gobbi, Flavia C P Rosin, Carlos Eduardo Dos Santos Ferreira, Lidiane Soares Sodre da Costa, Nelson Hamerschlak, Luciana Corrêa. Is Salivary Busulfan the Cause of Oral Mucositis and the Changes in Salivary Antioxidant Enzymes After Hematopoietic Cell Transplantation?.
Therapeutic drug monitoring.
2020 08; 42(4):565-571. doi:
10.1097/ftd.0000000000000757. [PMID: 32205679] - Shuai Yu, Yong Zhao, Fa-Li Zhang, Ya-Qi Li, Wei Shen, Zhong-Yi Sun. Chestnut polysaccharides benefit spermatogenesis through improvement in the expression of important genes.
Aging.
2020 06; 12(12):11431-11445. doi:
10.18632/aging.103205. [PMID: 32568099] - Kamal M Matar, Salem H Alshemmari, Samar Refaat, Alia Anwar. UPLC-Tandem Mass Spectrometry for Quantification of Busulfan in Human Plasma: Application to Therapeutic Drug Monitoring.
Scientific reports.
2020 06; 10(1):8913. doi:
10.1038/s41598-020-65919-9. [PMID: 32488110] - Abed Pablo, Autumn R Breaud, William Clarke. Analysis of Busulfan in Plasma by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
Current protocols in toxicology.
2020 06; 84(1):e93. doi:
10.1002/cptx.93. [PMID: 32469450] - T G Borovskaya, A V Vychuzhanina, V A Grigor'eva, O V Kollantay, V E Goldberg, A M Dygai. Evaluation of the Effect of p-Tyrosol on the Level of DNA Damage in the DNA Comet Assay In Vivo.
Bulletin of experimental biology and medicine.
2020 Jun; 169(2):233-236. doi:
10.1007/s10517-020-04857-y. [PMID: 32651820] - Kenji Kishimoto, Daiichiro Hasegawa, Kei Irie, Akira Okada, Sayaka Nakamura, Akihiro Tamura, Nobuyuki Yamamoto, Aiko Kozaki, Atsuro Saito, Toshiaki Ishida, Shoji Fukushima, Yoshiyuki Kosaka. Pharmacokinetic analysis for model-supported therapeutic drug monitoring of busulfan in Japanese pediatric hematopoietic stem cell transplantation recipients.
Pediatric transplantation.
2020 06; 24(4):e13696. doi:
10.1111/petr.13696. [PMID: 32196880] - Anne Rix, Natascha Ingrid Drude, Anna Mrugalla, Ferhan Baskaya, Koon Yan Pak, Brian Gray, Hans-Jürgen Kaiser, René Hany Tolba, Eva Fiegle, Wiltrud Lederle, Felix Manuel Mottaghy, Fabian Kiessling. Assessment of Chemotherapy-Induced Organ Damage with Ga-68 Labeled Duramycin.
Molecular imaging and biology.
2020 06; 22(3):623-633. doi:
10.1007/s11307-019-01417-3. [PMID: 31396770] - Zvi Teitelbaum, Laila Nassar, Inna Scherb, Dorit Fink, Gil Ring, Yael Lurie, Norberto Krivoy, Yedidia Bentur, Edna Efrati, Daniel Kurnik. Limited Sampling Strategies Supporting Individualized Dose Adjustment of Intravenous Busulfan in Children and Young Adults.
Therapeutic drug monitoring.
2020 06; 42(3):427-434. doi:
10.1097/ftd.0000000000000700. [PMID: 31479045] - Fatemeh Soghra Jahed, Samin Hamidi, Saba Ghaffary, Babak Nejati. Dispersive micro solid phase extraction of busulfan from plasma samples using novel mesoporous sorbent prior to determination by HPLC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 May; 1145(?):122091. doi:
10.1016/j.jchromb.2020.122091. [PMID: 32315975] - Matthijs W van Hoogdalem, Chie Emoto, Tsuyoshi Fukuda, Tomoyuki Mizuno, Parinda A Mehta, Alexander A Vinks. Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients.
British journal of clinical pharmacology.
2020 05; 86(5):933-943. doi:
10.1111/bcp.14202. [PMID: 31851762] - Qianqian Luo, Ranran Liu, Li Wang, Yun Hou, Hongqin Zhang. The Effects of Inhibin B in the Chemotherapy Drug-Induced Premature Ovarian Insufficiency Mice and hPMSCs Treatment.
Reproductive sciences (Thousand Oaks, Calif.).
2020 05; 27(5):1148-1155. doi:
10.1007/s43032-019-00128-y. [PMID: 31993999] - Aleksandar Radujkovic, Ute Hegenbart, Carsten Müller-Tidow, Klaus Herfarth, Peter Dreger, Thomas Luft. High leukemia-free survival after TBI-based conditioning and mycophenolate mofetil-containing immunosuppression in patients allografted for chronic myelomonocytic leukemia: a single-center experience.
Annals of hematology.
2020 Apr; 99(4):855-866. doi:
10.1007/s00277-020-03952-4. [PMID: 32036420] - Ning Qu, Miyuki Kuramasu, Kenta Nagahori, Yuki Ogawa, Shogo Hayashi, Yoshie Hirayanagi, Hayato Terayama, Kaori Suyama, Kou Sakabe, Masahiro Itoh. Co-Administration of the Traditional Medicines Hachimi-Jio-Gan and Hochu-Ekki-To Can Reverse Busulfan-Induced Aspermatogenesis.
International journal of molecular sciences.
2020 Mar; 21(5):. doi:
10.3390/ijms21051716. [PMID: 32138301] - Tal Schechter, Evelio Perez-Albuerne, Tiffany F Lin, Meredith S Irwin, Mohammed Essa, Ami V Desai, Haydar Frangoul, Gregory Yanik, L Lee Dupuis, David Jacobsohn, Morris Kletzel, Mark Ranalli, Sandeep Soni, Alix E Seif, Stephan Grupp, Christopher C Dvorak. Veno-occlusive disease after high-dose busulfan-melphalan in neuroblastoma.
Bone marrow transplantation.
2020 03; 55(3):531-537. doi:
10.1038/s41409-018-0298-y. [PMID: 30181580] - Adrian Martuszewski, Patrycja Paluszkiewicz, Katarzyna Sierżęga-Staykov, Elżbieta Wawrzyniak-Dzierżek, Małgorzata Salamonowicz-Bodzioch, Jowita Frączkiewicz, Małgorzata Janeczko-Czarnecka, Monika Mielcarek-Siedziuk, Mateusz Nowak, Nel Dąbrowska-Leonik, Beata Wolska-Kuśnierz, Katarzyna Gul, Katarzyna Bąbol-Pokora, Wojciech Młynarski, Krzysztof Kałwak, Marek Ussowicz. Successful Allogeneic Stem Cell Transplantation in Nuclear Factor-Kappa B Essential Modulator Deficiency Syndrome After Treosulfan-Based Conditioning: A Case Report.
Transplantation proceedings.
2020 Mar; 52(2):647-652. doi:
10.1016/j.transproceed.2019.11.033. [PMID: 32035679] - Ana Dilo, Youssef Daali, Jules Desmeules, Yves Chalandon, Chakradhara R S Uppugunduri, Marc Ansari. Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children.
Therapeutic drug monitoring.
2020 02; 42(1):111-117. doi:
10.1097/ftd.0000000000000673. [PMID: 31348116] - Bin Lei, Lixia Xie, Shoubo Zhang, Daojun Lv, Fangpeng Shu, Yushu Deng. UBE2W down-regulation promotes cell apoptosis and correlates with hypospermatogenesis.
Andrologia.
2020 Feb; 52(1):e13474. doi:
10.1111/and.13474. [PMID: 31710394] - Venkateswaran Vellaichamy Swaminathan, Ramya Uppuluri, Shivani Patel, Kesavan Melarcode Ramanan, Nikila Ravichandran, Indira Jayakumar, Lakshman Vaidhyanathan, Revathi Raj. Treosulfan-based reduced toxicity hematopoietic stem cell transplantation in X-linked agammaglobulinemia: A cost-effective alternative to long-term immunoglobulin replacement in developing countries.
Pediatric transplantation.
2020 02; 24(1):e13625. doi:
10.1111/petr.13625. [PMID: 31821668] - Kaoru Morita, Masahiro Ashizawa, Yumiko Toda, Takashi Ikeda, Shin-Ichiro Kawaguchi, Shoko Ito, Shin-Ichi Ochi, Takashi Nagayama, Kiyomi Mashima, Kento Umino, Daisuke Minakata, Hirofumi Nakano, Ryoko Yamasaki, Chihiro Yamamoto, Kaoru Hatano, Shin-Ichiro Fujiwara, Kazuya Sato, Iekuni Oh, Ken Ohmine, Kazuo Muroi, Kana Matsumoto, Yoshinobu Kanda. Salvage Chemotherapy Followed by Autologous Stem-Cell Transplantation Using Targeted Busulfan for Refractory Diffuse Large B-Cell Lymphoma With Dialysis-Dependent End-Stage Renal Disease.
Clinical lymphoma, myeloma & leukemia.
2020 02; 20(2):e92-e96. doi:
10.1016/j.clml.2019.11.004. [PMID: 31787588] - Dimana Dimitrova, Juan Gea-Banacloche, Seth M Steinberg, Jennifer L Sadler, Stephanie N Hicks, Ellen Carroll, Jennifer S Wilder, Mark Parta, Lauren Skeffington, Thomas E Hughes, Jenny E Blau, Miranda M Broadney, Jeremy J Rose, Amy P Hsu, Rochelle Fletcher, Natalia S Nunes, Xiao-Yi Yan, William G Telford, Veena Kapoor, Jeffrey I Cohen, Alexandra F Freeman, Elizabeth Garabedian, Steven M Holland, Andrea Lisco, Harry L Malech, Luigi D Notarangelo, Irini Sereti, Nirali N Shah, Gulbu Uzel, Christa S Zerbe, Daniel H Fowler, Ronald E Gress, Christopher G Kanakry, Jennifer A Kanakry. Prospective Study of a Novel, Radiation-Free, Reduced-Intensity Bone Marrow Transplantation Platform for Primary Immunodeficiency Diseases.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2020 01; 26(1):94-106. doi:
10.1016/j.bbmt.2019.08.018. [PMID: 31493539] - Seitaro Terakura, Makoto Onizuka, Mariko Fukumoto, Yachiyo Kuwatsuka, Akio Kohno, Yukiyasu Ozawa, Koichi Miyamura, Yuichiro Inagaki, Masashi Sawa, Yoshiko Atsuta, Ritsuro Suzuki, Tomoki Naoe, Yoshihisa Morishita, Makoto Murata. Analysis of glutathione S-transferase and cytochrome P450 gene polymorphism in recipients of dose-adjusted busulfan-cyclophosphamide conditioning.
International journal of hematology.
2020 Jan; 111(1):84-92. doi:
10.1007/s12185-019-02741-8. [PMID: 31555969] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Adrian Martuszewski, Patrycja Paluszkiewicz, Elżbieta Wawrzyniak-Dzierżek, Magdalena Drożyńska-Duklas, Katarzyna Bąbol-Pokora, Małgorzata Myśliwiec, Donata Szymczak, Ninela Irga-Jaworska, Wojciech Młynarski, Krzysztof Kałwak, Marek Ussowicz. Successful Salvage Haploidentical Alpha-Beta T Cell-Depleted Stem Cell Transplantation After Busulfan-Based Myeloablation in a Patient With IPEX Syndrome: A Case Report.
Transplantation proceedings.
2019 Nov; 51(9):3150-3154. doi:
10.1016/j.transproceed.2019.07.007. [PMID: 31611124] - Iracema Esteves, Fabio Pires Souza Santos, Juliana Folloni Fernandes, Adriana Seber, José Salvador Rodrigues Oliveira, Nelson Hamerschlak, Fabio Rodrigues Kerbauy, Borje S Andersson, Marcos de Lima. Pharmacokinetics analysis results are similar for oral compared to intravenous busulfan in patients undergoing hematopoietic stem cell transplantation, except for the earlier onset of mucositis. A controlled clinical study.
Bone marrow transplantation.
2019 11; 54(11):1799-1804. doi:
10.1038/s41409-019-0521-5. [PMID: 31089278] - Zheng-Ping Yu, Jia-Hua Ding, Ai-Ning Sun, Bao-An Chen, Zheng Ge, De-Pei Wu. A New Conditioning Regimen Can Significantly Promote Post-Transplant Immune Reconstitution and Improve the Outcome of Umbilical Cord Blood Transplantation for Patients.
Stem cells and development.
2019 10; 28(20):1376-1383. doi:
10.1089/scd.2019.0139. [PMID: 31464164] - Cuncan Deng, Yun Xie, Chi Zhang, Bin Ouyang, Haicheng Chen, Linyan Lv, Jiahui Yao, Xiaoyan Liang, Yuanyuan Zhang, Xiangzhou Sun, Chunhua Deng, Guihua Liu. Urine-Derived Stem Cells Facilitate Endogenous Spermatogenesis Restoration of Busulfan-Induced Nonobstructive Azoospermic Mice by Paracrine Exosomes.
Stem cells and development.
2019 10; 28(19):1322-1333. doi:
10.1089/scd.2019.0026. [PMID: 31311428] - Naoya Uchida, Tina Nassehi, Claire M Drysdale, Jackson Gamer, Morgan Yapundich, Aylin C Bonifacino, Allen E Krouse, Nathaniel Linde, Matthew M Hsieh, Robert E Donahue, Cynthia E Dunbar, Leslie S Kean, John F Tisdale. Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model.
Molecular therapy : the journal of the American Society of Gene Therapy.
2019 09; 27(9):1586-1596. doi:
10.1016/j.ymthe.2019.05.022. [PMID: 31253582] - Ryan C Schofield, Heather J Landau, Sergio A Giralt, Gunjan L Shah, Michael Scordo, Andrew Lin, Elaine Zanutto, Lakshmi V Ramanathan, Melissa S Pessin, Dean C Carlow. Measurement of the DNA alkylating agents busulfan and melphalan in human plasma by mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Sep; 1125(?):121711. doi:
10.1016/j.jchromb.2019.121711. [PMID: 31376591] - Jeannine S McCune, Christine M Quinones, James Ritchie, Paul A Carpenter, Erik van Maarseveen, Rosa F Yeh, Claudio Anasetti, Jaap J Boelens, Nelson Hamerschlak, Moustapha Hassan, Hyoung Jin Kang, Yoshinobu Kanda, Angelo Paci, Miguel-Angel Perales, Peter J Shaw, Victoria L Seewaldt, Bipin N Savani, Angela Hsieh, Betsy Poon, Mohamad Mohty, Michael A Pulsipher, Marcelo Pasquini, L Lee Dupuis. Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2019 09; 25(9):1890-1897. doi:
10.1016/j.bbmt.2019.05.021. [PMID: 31136799] - Drishya Rajan Parachalil, Deirdre Commerford, Franck Bonnier, Igor Chourpa, Jennifer McIntyre, Hugh J Byrne. Raman spectroscopy as a potential tool for label free therapeutic drug monitoring in human serum: the case of busulfan and methotrexate.
The Analyst.
2019 Aug; 144(17):5207-5214. doi:
10.1039/c9an00801b. [PMID: 31355390] - Lan Sun, Na Wang, Yi Chen, Liyuan Tang, Chongyun Xing, Nina Lu, Yifen Shi, Yongyong Ma, Fengyang Lin, Kang Yu, Jianhua Feng. Unrelated Donor Peripheral Blood Stem Cell Transplantation for Patients with β-Thalassemia Major Based on a Novel Conditioning Regimen.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2019 08; 25(8):1592-1596. doi:
10.1016/j.bbmt.2019.03.028. [PMID: 30951841] - Karen Sweiss, Gregory S Calip, Annie L Oh, Damiano Rondelli, Pritesh R Patel. Renal dysfunction within 90 days of FluBu4 predicts early and late mortality.
Bone marrow transplantation.
2019 07; 54(7):980-986. doi:
10.1038/s41409-018-0361-8. [PMID: 30604772] - Selami Demirci, Juan J Haro Mora, Morgan Yapundich, Claire Drysdale, Jackson Gamer, Tina Nassehi, Aylin C Bonifacino, Allen E Krouse, Nathaniel S Linde, Robert E Donahue, John F Tisdale, Naoya Uchida. Fetal hemoglobin and F-cell variance in mobilized CD34+ cell-transplanted rhesus monkeys.
Experimental hematology.
2019 07; 75(?):21-25.e1. doi:
10.1016/j.exphem.2019.05.005. [PMID: 31173819] - Takuro Nishikawa, Hiroki Yamaguchi, Kazuro Ikawa, Kazutaka Nakayama, Erika Higashi, Emiko Miyahara, Takanari Abematsu, Shunsuke Nakagawa, Yuichi Kodama, Takayuki Tanabe, Akari Shigemi, Yuichi Shinkoda, Yasuhiro Okamoto, Yasuo Takeda, Yoshifumi Kawano. Influence of GST polymorphisms on busulfan pharmacokinetics in Japanese children.
Pediatrics international : official journal of the Japan Pediatric Society.
2019 Jun; 61(6):558-565. doi:
10.1111/ped.13859. [PMID: 30963629] - Marjan D Manshadi, Shadan Navid, Yumi Hoshino, Erfan Daneshi, Parastoo Noory, Mehdi Abbasi. The effects of human menstrual blood stem cells-derived granulosa cells on ovarian follicle formation in a rat model of premature ovarian failure.
Microscopy research and technique.
2019 Jun; 82(6):635-642. doi:
10.1002/jemt.23120. [PMID: 30582244] - Ibrahim El-Serafi, Orlaith Loy, Ying Zhao, Sandra Oerther, Jonas Mattsson. Pre-formulation investigations for establishing a protocol for treosulfan handling and activation.
Pharmaceutical development and technology.
2019 Jun; 24(5):639-648. doi:
10.1080/10837450.2018.1551903. [PMID: 30474459] - Eun Jin Lee, Nuri Park, Sang Hee Lee, Woochang Lee, Hyun Soo Kim, Sail Chun, Won-Ki Min. A Simple and Accurate Liquid Chromatography-Tandem Mass Spectrometry Method for Therapeutic Drug Monitoring of Busulfan in Plasma.
Annals of clinical and laboratory science.
2019 Mar; 49(2):212-217. doi:
NULL. [PMID: 31028066] - B Al-Saud, M Al-Jomaie, A Al-Ghonaium, A Al-Ahmari, H Al-Mousa, S Al-Muhsen, A Al-Seraihy, R Arnaout, S Elshorbagi, H Al-Dhekri, M Ayas. Haematopoietic stem cell transplant for hyper-IgM syndrome due to CD40 defects: a single-centre experience.
Bone marrow transplantation.
2019 01; 54(1):63-67. doi:
10.1038/s41409-018-0219-0. [PMID: 29884852] - Farzaneh Dehghani, Narges Sotoude, Hossein Bordbar, M R Panjeshahin, Saied Karbalay-Doust. The use of platelet-rich plasma (PRP) to improve structural impairment of rat testis induced by busulfan.
Platelets.
2019; 30(4):513-520. doi:
10.1080/09537104.2018.1478400. [PMID: 29883240] - Maryam Behfar, Lili Koochakzadeh, Nafise Yazdanian, Pourya Salajegheh, Tahereh Rostami, Nazanin Khodayari-Namini, Ardeshir Ghavamzadeh, Amir Ali Hamidieh. Outcome of allogeneic Hematopoietic Stem Cell Transplantation on Diamond-Blackfan anemia using busulfan-based myeloablative regimen.
The Turkish journal of pediatrics.
2019; 61(3):407-412. doi:
10.24953/turkjped.2019.03.013. [PMID: 31916719] - Moaath Mustafa Ali, Donna M Corrigan, Lisa A Rybicki, Melissa A Yurch, Kelly Cherni, Hien Liu, Robert Dean, Betty Hamilton, Brad Pohlman, Steven Andresen, Matt Kalaycio, Brian J Bolwell, Navneet S Majhail, Ronald Sobecks. Intravenous compared to oral busulfan with cyclophosphamide for autologous hematopoietic cell transplant conditioning for plasma cell myeloma.
Hematology/oncology and stem cell therapy.
2018 Dec; 11(4):253-256. doi:
10.1016/j.hemonc.2018.03.006. [PMID: 29705567] - Yabin Gong, Zhilong Zhang, Zhanglin Chang, Hao Zhou, Ruqian Zhao, Bin He. Inactivation of glycogen synthase kinase-3α is required for mitochondria-mediated apoptotic germ cell phagocytosis in Sertoli cells.
Aging.
2018 11; 10(11):3104-3116. doi:
10.18632/aging.101614. [PMID: 30398976] - Michał Romański, Anna Zacharzewska, Artur Teżyk, Franciszek K Główka. In Vivo Red Blood Cells/Plasma Partition Coefficient of Treosulfan and Its Active Monoepoxide in Rats.
European journal of drug metabolism and pharmacokinetics.
2018 Oct; 43(5):565-571. doi:
10.1007/s13318-018-0469-7. [PMID: 29542019] - Parva Nasimi, Mohammad Reza Tabandeh, Sayad Roohi. Busulfan-mediated oxidative stress and genotoxicity decrease in sperm of Satureja Khuzestanica essential oil-administered mice.
Systems biology in reproductive medicine.
2018 Oct; 64(5):348-357. doi:
10.1080/19396368.2018.1449915. [PMID: 29557179] - Ning Qu, Miyuki Kuramasu, Yoshie Hirayanagi, Kenta Nagahori, Shogo Hayashi, Yuki Ogawa, Hayato Terayama, Kaori Suyama, Munekazu Naito, Kou Sakabe, Masahiro Itoh. Gosha-Jinki-Gan Recovers Spermatogenesis in Mice with Busulfan-Induced Aspermatogenesis.
International journal of molecular sciences.
2018 Sep; 19(9):. doi:
10.3390/ijms19092606. [PMID: 30177609] - Atsuko Kawazoe, Tomoo Funaki, Seongryul Kim. Population Pharmacokinetic Analysis of Busulfan in Japanese Pediatric and Adult HCT Patients.
Journal of clinical pharmacology.
2018 09; 58(9):1196-1204. doi:
10.1002/jcph.1120. [PMID: 29663421] - Can Boga, Mahmut Yeral, Ciğdem Gereklioglu, Suheyl Asma, Erkan Maytalman, Pelin Aytan, Ilknur Kozanoglu, Cagla Sariturk, Hakan Ozdogu. Effects of two doses of anti-T lymphocyte globulin-Fresenius given after full-match sibling stem cell transplantation in acute myeloblastic leukemia patients who underwent myeloablative fludarabine/busulfan conditioning.
Hematology/oncology and stem cell therapy.
2018 Sep; 11(3):149-157. doi:
10.1016/j.hemonc.2018.01.004. [PMID: 29474820] - Yan Yue, Zeliang Song, Junhui Li, Shunqiao Feng, Rong Liu, Xiaodong Shi. Posttransplant Cyclophosphamide for HLA-haploidentical Transplantation in Patients With Mucopolysaccharidosis.
Journal of pediatric hematology/oncology.
2018 08; 40(6):e350-e354. doi:
10.1097/mph.0000000000001157. [PMID: 29621063] - Qixin Sun, Bingyi Wu, Hekui Lan, Fanyi Meng, Xiaoxiao Ma, Xinxin Chen, Zhiwei Huang, Qianqian Yao, Jianhui Xu, Yuxian Huang, Shaojie Wu, Zhigang Zhu. Haploidentical haematopoietic stem cell transplantation for thalassaemia major based on an FBCA conditioning regimen.
British journal of haematology.
2018 08; 182(4):554-558. doi:
10.1111/bjh.15438. [PMID: 29962035] - Divya Devadasan, Chiao-Wang Sun, Erik R Westin, Li-Chen Wu, Kevin M Pawlik, Tim M Townes, Frederick D Goldman. Bone Marrow Transplantation after Nonmyeloablative Treosulfan Conditioning Is Curative in a Murine Model of Sickle Cell Disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2018 08; 24(8):1554-1562. doi:
10.1016/j.bbmt.2018.04.011. [PMID: 29684562] - Mohammadreza Gholami, Abolfazl Abbaszadeh, Parastoo Baharvand, Afshin Hasanvand, Amin Hasanvand, Anneh Mohammad Gharravi. Protective effects of persian honey, Apis Mellifera Meda Skorikov on side effects of chemotherapy and ischemia/reperfusion induced testicular injury.
Journal of complementary & integrative medicine.
2018 May; 15(4):. doi:
10.1515/jcim-2016-0035. [PMID: 29791311] - Michał Romański, Franciszek Główka. Clinical bioanalysis of treosulfan and its epoxides: The importance of collected blood processing for valid pharmacokinetic results.
Journal of pharmaceutical and biomedical analysis.
2018 May; 153(?):199-203. doi:
10.1016/j.jpba.2018.02.049. [PMID: 29501039] - Yi Xiao, Xiaohan Li, Xiaowei Fu. A rapid and simple LC-MS/MS method for personalized busulfan dosing in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT).
Clinica chimica acta; international journal of clinical chemistry.
2018 Apr; 479(?):190-195. doi:
10.1016/j.cca.2018.01.020. [PMID: 29341904] - Melanie White-Koning, Caroline Osborne, Angelo Paci, Alan V Boddy, Etienne Chatelut, Gareth J Veal. Investigating the potential impact of dose banding for systemic anti-cancer therapy in the paediatric setting based on pharmacokinetic evidence.
European journal of cancer (Oxford, England : 1990).
2018 03; 91(?):56-67. doi:
10.1016/j.ejca.2017.11.029. [PMID: 29335155] - Kristina M Brooks, Paul Jarosinski, Thomas Hughes, Elizabeth Kang, Nirali N Shah, John B Le Gall, Dennis D Hickstein, Suk See De Ravin, Jomy M George, Parag Kumar. Test Dose Pharmacokinetics in Pediatric Patients Receiving Once-Daily IV Busulfan Conditioning for Hematopoietic Stem Cell Transplant: A Reliable Approach?.
Journal of clinical pharmacology.
2018 03; 58(3):332-339. doi:
10.1002/jcph.1049. [PMID: 29238995] - Eva Choong, Chakradhara Rao Satyanarayana Uppugunduri, Denis Marino, Melanie Kuntzinger, Fabienne Doffey-Lazeyras, Rodolfo Lo Piccolo, Yves Chalandon, Christina Peters, Youssef Daali, Marc Ansari. Therapeutic Drug Monitoring of Busulfan for the Management of Pediatric Patients: Cross-Validation of Methods and Long-Term Performance.
Therapeutic drug monitoring.
2018 02; 40(1):84-92. doi:
10.1097/ftd.0000000000000468. [PMID: 29189665] - Mohammad Siddiqi, Saima Nusrat, Parvez Alam, Sadia Malik, Sumit Kumar Chaturvedi, Mohammad Rehan Ajmal, Ali Saber Abdelhameed, Rizwan Hasan Khan. Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches.
International journal of biological macromolecules.
2018 Feb; 107(Pt B):1414-1421. doi:
10.1016/j.ijbiomac.2017.10.006. [PMID: 28987797] - L-P Xu, Z-L Xu, F-R Wang, X-D Mo, T-T Han, W Han, Y-H Chen, Y-Y Zhang, J-Z Wang, Y Wang, C-H Yan, Y-Q Sun, F-F Tang, X-H Zhang, X-J Huang. Unmanipulated haploidentical transplantation conditioning with busulfan, cyclophosphamide and anti-thymoglobulin for adult severe aplastic anaemia.
Bone marrow transplantation.
2018 02; 53(2):188-192. doi:
10.1038/bmt.2017.237. [PMID: 29334367] - Dhawal Chobisa, Ketan Patel, Jasmin Monpara, Mayank Patel, Pradeep Vavia. Development and characterization of an organic solvent free, proliposomal formulation of Busulfan using quality by design approach.
International journal of pharmaceutics.
2018 Jan; 535(1-2):360-370. doi:
10.1016/j.ijpharm.2017.11.007. [PMID: 29126906] - Sara A Mohamed, Shahinaz M Shalaby, Mohamed Abdelaziz, Soumia Brakta, William D Hill, Nahed Ismail, Ayman Al-Hendy. Human Mesenchymal Stem Cells Partially Reverse Infertility in Chemotherapy-Induced Ovarian Failure.
Reproductive sciences (Thousand Oaks, Calif.).
2018 01; 25(1):51-63. doi:
10.1177/1933719117699705. [PMID: 28460567] - Nicolas Simon, Valérie Coiteux, Bénédicte Bruno, Sophie Taque, Amandine Charbonnier, Laetitia Souchet, Laure Vincent, Ibrahim Yakoub-Agha, Yves Chalandon. [Dose adaptation of the drugs used for hematopoietic stem-cell transplantation in patients with comorbidity: Obesity, chronic renal disease or hepatopathy: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Bulletin du cancer.
2017 Dec; 104(12S):S99-S105. doi:
10.1016/j.bulcan.2017.07.010. [PMID: 29173979] - Barbara Spitzer, Ann A Jakubowski, Esperanza B Papadopoulos, Kirsten Fuller, Patrick D Hilden, James W Young, Juliet N Barker, Guenther Koehne, Miguel-Angel Perales, Katharine C Hsu, Marcel R van den Brink, Nancy A Kernan, Susan E Prockop, Andromachi Scaradavou, Hugo Castro-Malaspina, Richard J O'Reilly, Farid Boulad. A Chemotherapy-Only Regimen of Busulfan, Melphalan, and Fludarabine, and Rabbit Antithymocyte Globulin Followed by Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplantations for the Treatment of Myeloid Malignancies.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2017 Dec; 23(12):2088-2095. doi:
10.1016/j.bbmt.2017.07.004. [PMID: 28711727] - Michał Romański, Anna Kasprzyk, Mateusz Walczak, Agnieszka Ziółkowska, Franciszek Główka. Disposition of treosulfan and its active monoepoxide in a bone marrow, liver, lungs, brain, and muscle: Studies in a rat model with clinical relevance.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2017 Nov; 109(?):616-623. doi:
10.1016/j.ejps.2017.09.011. [PMID: 28916482] - L M Bezinelli, F P Eduardo, D L C de Carvalho, C E Dos Santos Ferreira, E V de Almeida, L R Sanches, I Esteves, P V Campregher, N Hamerschlak, L Corrêa. Therapeutic salivary monitoring of IV busulfan in patients undergoing hematopoietic stem cell transplantation: a pilot study.
Bone marrow transplantation.
2017 Oct; 52(10):1384-1389. doi:
10.1038/bmt.2017.142. [PMID: 28737776]