Bicarbonate ion (BioDeep_00000004408)
Secondary id: BioDeep_00001894040
代谢物信息卡片
Bicarbonate ion
化学式: CHO3- (60.9925696)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 98.67%
分子结构信息
SMILES: C(=O)(O)[O-]
InChI: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
描述信息
D019995 - Laboratory Chemicals > D002021 - Buffers > D001639 - Bicarbonates
同义名列表
1 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:17544
- KEGG: C00288
- PubChem: 769
- ChEMBL: CHEMBL363707
- MeSH: Bicarbonates
- CAS: 71-52-3
- PubChem: 3583
- PDB-CCD: BCT
- 3DMET: B00080
分类词条
相关代谢途径
Reactome(21)
- Metabolism
- Disease
- Amino acid and derivative metabolism
- Metabolism of lipids
- Transport of small molecules
- SLC-mediated transmembrane transport
- Urea cycle
- Ion channel transport
- Stimuli-sensing channels
- Nucleotide metabolism
- Disorders of transmembrane transporters
- SLC transporter disorders
- Transport of inorganic cations/anions and amino acids/oligopeptides
- Fatty acid metabolism
- Carbohydrate metabolism
- Glucose metabolism
- Fatty acyl-CoA biosynthesis
- Carnitine metabolism
- Gluconeogenesis
- Branched-chain amino acid catabolism
- De novo synthesis of UMP
BioCyc(39)
- anaerobic energy metabolism (invertebrates, mitochondrial)
- superpathway of anaerobic energy metabolism (invertebrates)
- superpathway of demethylmenaquinol-8 biosynthesis I
- 2-carboxy-1,4-naphthoquinol biosynthesis
- superpathway of menaquinol-8 biosynthesis I
- superpathway of chorismate metabolism
- superpathway of sterol biosynthesis
- urea cycle
- superpathway of arginine and polyamine biosynthesis
- superpathway of L-citrulline metabolism
- formaldehyde assimilation I (serine pathway)
- purine nucleotides de novo biosynthesis I
- superpathway of histidine, purine, and pyrimidine biosynthesis
- mixed acid fermentation
- L-valine degradation I
- TCA cycle, aerobic respiration
- L-arginine biosynthesis II (acetyl cycle)
- UMP biosynthesis
- itaconate biosynthesis
- superpathway of histidine, purine and pyrimidine biosynthesis
- leucine degradation IV
- TCA cycle VI (obligate autotrophs)
- glutamine biosynthesis III
- gluconeogenesis II (Methanobacterium thermoautotrophicum)
- Methanobacterium thermoautotrophicum biosynthetic metabolism
- methylaspartate cycle
- propanoyl CoA degradation I
- 2-oxobutanoate degradation I
- reductive TCA cycle I
- L-leucine degradation I
- L-arginine biosynthesis I (via L-ornithine)
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
- C4 photosynthetic carbon assimilation cycle, NAD-ME type
- superpathway of L-methionine salvage and degradation
- arginine biosynthesis I
- sitosterol degradation to androstenedione
- nickel cofactor biosynthesis
- cyclopropane fatty acid (CFA) biosynthesis
- fatty acid biosynthesis -- elongase pathway
PlantCyc(6)
代谢反应
2979 个相关的代谢反应过程信息。
Reactome(307)
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Nucleobase biosynthesis:
ATP + H2O + L-Gln + XMP ⟶ AMP + GMP + L-Glu + PPi - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ N-carbamoyl-L-aspartate + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Metabolism of polyamines:
GAA + SAM ⟶ CRET + H+ + SAH - Urea cycle:
CAP + L-Orn ⟶ L-Cit + Pi - De novo synthesis of UMP:
CAP + L-Asp ⟶ N-carbamoyl-L-aspartate + Pi - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Nucleobase biosynthesis:
ATP + H2O + L-Gln + XMP ⟶ AMP + GMP + L-Glu + PPi - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ N-carbamoyl-L-aspartate + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Metabolism of polyamines:
GAA + SAM ⟶ CRET + H+ + SAH - Urea cycle:
CAP + L-Orn ⟶ L-Cit + Pi - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Metabolism of polyamines:
GAA + SAM ⟶ CRET + H+ + SAH - Urea cycle:
ATP + L-Asp + L-Cit ⟶ AMP + ARSUA + PPi - Metabolism of lipids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN - Fatty acid metabolism:
Ac-CoA + H2O ⟶ CH3COO- + CoA-SH - Fatty acyl-CoA biosynthesis:
ATP + CoA-SH + VLCFA ⟶ AMP + PPi + VLCFA-CoA - Import of palmitoyl-CoA into the mitochondrial matrix:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Metabolism of lipids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN - Fatty acid metabolism:
Ac-CoA + H2O ⟶ CH3COO- + CoA-SH - Fatty acyl-CoA biosynthesis:
ATP + CoA-SH + VLCFA ⟶ AMP + PPi + VLCFA-CoA - Import of palmitoyl-CoA into the mitochondrial matrix:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CoA + VLCFA ⟶ AMP + PPi + VLCFA-CoA - Import of palmitoyl-CoA into the mitochondrial matrix:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
H+ + HCO3- ⟶ H2O + carbon dioxide - Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
CHOL + NPC2 ⟶ NPC2:CHOL - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
H+ + HCO3- ⟶ H2O + carbon dioxide - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
H+ + HCO3- ⟶ H2O + carbon dioxide - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
H+ + HCO3- ⟶ H2O + carbon dioxide - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Transport of small molecules:
CHOL + phosphatidylcholines ⟶ 1-acyl LPC + CHEST - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Transport of small molecules:
Oxygen + TPNH + heme ⟶ BV + CO + Fe2+ + H2O + TPN - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - Transport of small molecules:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
Oxygen + Protonated Carbamino DeoxyHbA ⟶ H+ + OxyHbA + carbon dioxide - O2/CO2 exchange in erythrocytes:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up carbon dioxide and release oxygen:
H2O + carbon dioxide ⟶ H+ + HCO3- - Erythrocytes take up oxygen and release carbon dioxide:
H+ + HCO3- ⟶ H2O + carbon dioxide - Reversible hydration of carbon dioxide:
H2O + carbon dioxide ⟶ H+ + HCO3- - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + Cl- + H2O ⟶ ADP + Cl- + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - Transport of small molecules:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + Cl- + H2O ⟶ ADP + Cl- + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - ABC-family proteins mediated transport:
ATP + CHOL + H2O ⟶ ADP + CHOL + Pi - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Carbohydrate metabolism:
D-glucuronate + H+ + TPNH ⟶ L-gulonate + TPN - Glucose metabolism:
ATP + Fru(6)P ⟶ ADP + F1,6PP - Gluconeogenesis:
Glu + OAA ⟶ 2OG + L-Asp - Metabolism of lipids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
Mal-CoA + PALM-CoA ⟶ 3OOD-CoA + CoA-SH + carbon dioxide - Carnitine metabolism:
CAR + PALM-CoA ⟶ CoA-SH + L-PCARN - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
H2O + L-Arg ⟶ L-Orn + Urea - Carbohydrate metabolism:
L-gulonate + NAD ⟶ 3-dehydro-L-gulonate + H+ + NADH - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
H+ + OMP ⟶ UMP + carbon dioxide - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Carbohydrate metabolism:
D-glucuronate + H+ + TPNH ⟶ L-gulonate + TPN - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
GTP + IMP + L-Asp ⟶ ADS + GDP + H+ + Pi - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
ATP + L-Asp + L-Cit ⟶ AMP + ARSUA + PPi - Carbohydrate metabolism:
D-glucuronate + H+ + TPNH ⟶ L-gulonate + TPN - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Metabolism of lipids:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Fatty acid metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
ATP + Thy-dRib ⟶ ADP + TMP - Nucleotide biosynthesis:
GTP + IMP + L-Asp ⟶ ADS + GDP + H+ + Pi - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Carbohydrate metabolism:
L-gulonate + NAD ⟶ 3-dehydro-L-gulonate + H+ + NADH - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
3-oxopristanoyl-CoA + CoA-SH ⟶ 4,8,12-trimethyltridecanoyl-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
ATP + L-Asp + L-Cit ⟶ AMP + ARSUA + PPi - Metabolism:
H2O + PBG ⟶ HMBL + ammonia - Nucleotide metabolism:
CAP + L-Asp ⟶ N-carb-L-Asp + Pi - Pyrimidine metabolism: de novo synthesis of UMP:
CAP + L-Asp ⟶ N-carb-L-Asp + Pi - Carbohydrate metabolism:
D-glucuronate + H+ + TPNH ⟶ L-gulonate + TPN - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
ATP + L-Asp + L-Cit ⟶ AMP + ARSUA + PPi - Carbohydrate metabolism:
D-glucuronate + H+ + TPNH ⟶ L-gulonate + TPN - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
ATP + L-Asp + L-Cit ⟶ AMP + ARSUA + PPi - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Metabolism of lipids:
H2O + lysoPC ⟶ GPCho + LCFA(-) - Fatty acid metabolism:
12S-HpETE + GSH ⟶ 12S-HETE + GSSG + H2O - Fatty acyl-CoA biosynthesis:
Mal-CoA + PALM-CoA ⟶ 3OOD-CoA + CoA-SH + carbon dioxide - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
GTP + IMP + L-Asp ⟶ ADS + GDP + H+ + Pi - Nucleotide biosynthesis:
GTP + IMP + L-Asp ⟶ ADS + GDP + H+ + Pi - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Carbohydrate metabolism:
D-glucuronate + H+ + TPNH ⟶ L-gulonate + TPN - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
CAP + L-Orn ⟶ L-Cit + Pi - Metabolism:
CAR + propionyl CoA ⟶ CoA-SH + Propionylcarnitine - Carbohydrate metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
CAR + propionyl CoA ⟶ CoA-SH + Propionylcarnitine - Fatty acid metabolism:
CAR + propionyl CoA ⟶ CoA-SH + Propionylcarnitine - Fatty acyl-CoA biosynthesis:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
GTP + IMP + L-Asp ⟶ ADS + GDP + H+ + Pi - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
GAA + SAM ⟶ CRET + H+ + SAH - Urea cycle:
CAP + L-Orn ⟶ L-Cit + Pi - Metabolism:
GAA + SAM ⟶ CRET + H+ + SAH - Carbohydrate metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
ACA + H+ + NADH ⟶ NAD + bHBA - Fatty acid metabolism:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
GTP + IMP + L-Asp ⟶ ADS + GDP + H+ + Pi - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
GAA + SAM ⟶ CRET + H+ + SAH - Urea cycle:
CAP + L-Orn ⟶ L-Cit + Pi - Carbohydrate metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Fatty acid metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
Ade + PRPP ⟶ AMP + PPi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
ATP + L-Asp + L-Cit ⟶ AMP + ARSUA + PPi - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Carbohydrate metabolism:
D-glucuronate + H+ + TPNH ⟶ L-gulonate + TPN - Glucose metabolism:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Gluconeogenesis:
ATP + PYR + carbon dioxide ⟶ ADP + OAA + Pi - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acid metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Fatty acyl-CoA biosynthesis:
ATP + CIT + CoA-SH ⟶ ADP + Ac-CoA + OA + Pi - Carnitine metabolism:
ATP + Ac-CoA + HCO3- ⟶ ADP + Mal-CoA + Pi - Nucleotide metabolism:
AMP + H2O ⟶ Ade-Rib + Pi - Nucleotide biosynthesis:
ATP + CAIR + L-Asp ⟶ ADP + H+ + Pi + SAICAR - Pyrimidine biosynthesis:
CAP + L-Asp ⟶ H+ + N-carb-L-Asp + Pi - Amino acid and derivative metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Branched-chain amino acid catabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Urea cycle:
H2O + L-Arg ⟶ L-Orn + Urea
BioCyc(445)
- TCA cycle, aerobic respiration:
H2O + cis-aconitate ⟶ isocitrate - gluconeogenesis:
NAD+ + malate ⟶ CO2 + NADH + pyruvate - aspartate biosynthesis:
α-ketoglutarate + L-aspartate ⟶ L-glutamate + oxaloacetate - uridine-5'-phosphate biosynthesis:
H+ + orotidine-5'-phosphate ⟶ CO2 + UMP - pyrimidine ribonucleotides de novo biosynthesis:
H+ + orotidine-5'-phosphate ⟶ CO2 + UMP - arginine biosynthesis I:
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - superpathway of histidine, purine, and pyrimidine biosynthesis:
glt + imidazole acetol-phosphate ⟶ 2-oxoglutarate + L-histidinol-phosphate - superpathway of arginine and polyamine biosynthesis:
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - pyrimidine ribonucleotides de novo biosynthesis:
H+ + orotidine-5'-phosphate ⟶ CO2 + UMP - uridine-5'-phosphate biosynthesis:
H+ + orotidine-5'-phosphate ⟶ CO2 + UMP - methylmalonyl pathway:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + bicarbonate + propanoyl-CoA - valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + bicarbonate + propanoyl-CoA - cis-genanyl-CoA degradation:
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA ⟶ 3-(4-methylpent-3-en-1-yl)-pent-2-enedioyl-CoA + H2O - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - ethylbenzene degradation (anaerobic):
ATP + H2O + acetophenone + hydrogencarbonate ⟶ 3-oxo-3-phenylpropanoate + ADP + H+ + phosphate - gluconeogenesis II (Methanobacterium thermoautotrophicum):
CO + H2O + an oxidized ferredoxin [iron-sulfur] cluster ⟶ CO2 + H+ + a reduced ferredoxin [iron-sulfur] cluster - Methanobacterium thermoautotrophicum biosynthetic metabolism:
CO + H2O + an oxidized ferredoxin [iron-sulfur] cluster ⟶ CO2 + H+ + a reduced ferredoxin [iron-sulfur] cluster - C4 photosynthetic carbon assimilation cycle, PEPCK type:
H+ + hydrogencarbonate ⟶ CO2 + H2O - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - gluconeogenesis:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - urea cycle:
ATP + L-citrulline + asp ⟶ AMP + H+ + L-arginino-succinate + diphosphate - 2-oxobutanoate degradation:
2-oxobutanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - leucine degradation:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - valine degradation:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - propionyl-CoA degradation:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - superpathway of methionine degradation:
2-oxobutanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + propanoyl-CoA - UMP biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - 1,4-dihydroxy-6-naphthoate biosynthesis II:
3-[(1-carboxyvinyl)oxy]benzoate + H2O + SAM ⟶ 6-amino-6-deoxyfutalosine + H+ + hydrogencarbonate + met - 1,4-dihydroxy-6-naphthoate biosynthesis I:
3-[(1-carboxyvinyl)oxy]benzoate + H2O + SAM ⟶ 6-amino-6-deoxyfutalosine + H+ + hydrogencarbonate + met - urea cycle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - methylaspartate cycle:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - superpathway of demethylmenaquinol-6 biosynthesis II:
3-[(1-carboxyvinyl)oxy]benzoate + H2O + SAM ⟶ 6-amino-6-deoxyfutalosine + H+ + hydrogencarbonate + met - superpathway of the 3-hydroxypropanoate cycle:
H+ + hydrogencarbonate ⟶ CO2 + H2O - 3-hydroxypropanoate cycle:
H+ + hydrogencarbonate ⟶ CO2 + H2O - partial TCA cycle (obligate autotrophs):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - 3-hydroxypropanoate/4-hydroxybutanate cycle:
NADP+ + propanoyl-CoA ⟶ H+ + NADPH + acryloyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis II:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - UMP biosynthesis III:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - propanoyl CoA degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + H2O ⟶ N-carbamoyl-L-aspartate + H+ - L-glutamine biosynthesis III:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - 2,4-dinitrotoluene degradation:
2,4-dinitrotoluene + NADH + O2 ⟶ 4-methyl-5-nitrocatechol + NAD+ + nitrite - 2-oxobutanoate degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - naphthalene degradation (anaerobic):
hydrogencarbonate + naphthalene ⟶ 2-naphthoate + H2O - reductive TCA cycle I:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - incomplete reductive TCA cycle:
ATP + hydrogencarbonate + pyruvate ⟶ ADP + H+ + oxaloacetate + phosphate - anaerobic energy metabolism (invertebrates, mitochondrial):
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - mixed acid fermentation:
ATP + pyruvate ⟶ ADP + H+ + phosphoenolpyruvate - superpathway of anaerobic energy metabolism (invertebrates):
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - superpathway of arginine and polyamine biosynthesis:
cadaverine + dAdoMet ⟶ S-methyl-5'-thioadenosine + H+ + aminopropylcadaverine - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - inosine-5'-phosphate biosynthesis III:
AIR + ATP + hydrogencarbonate ⟶ ADP + H+ + N5-CAIR + phosphate - inosine-5'-phosphate biosynthesis I:
AIR + ATP + hydrogencarbonate ⟶ ADP + H+ + N5-CAIR + phosphate - nickel cofactor biosynthesis:
hydrogencarbonate + nicotinate adenine dinucleotide ⟶ AMP + H+ + pyridin-1-ium-3,5-dicarboxylate mononucleotide - formaldehyde assimilation I (serine pathway):
a tetrahydrofolate + formaldehyde ⟶ H2O + a 5,10-methylenetetrahydrofolate - gluconeogenesis III:
ATP + hydrogencarbonate + pyruvate ⟶ ADP + H+ + oxaloacetate + phosphate - jadomycin biosynthesis:
dTDP-β-L-digitoxose + jadomycin A ⟶ H+ + dTDP + jadomycin B - L-arginine biosynthesis III (via N-acetyl-L-citrulline):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis IV (archaebacteria):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis II (acetyl cycle):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of L-citrulline metabolism:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - glyoxylate assimilation:
NADP+ + propanoyl-CoA ⟶ H+ + NADPH + acryloyl-CoA - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ (L-threonylcarbamoyl)adenylate + H2O + diphosphate - sitosterol degradation to androstenedione:
17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA ⟶ androst-4-ene-3,17-dione + propanoyl-CoA - superpathway of menaquinol-8 biosynthesis II:
3-[(1-carboxyvinyl)oxy]benzoate + H2O + SAM ⟶ 6-amino-6-deoxyfutalosine + H+ + hydrogencarbonate + met - superpathway of menaquinol-8 biosynthesis III:
3-[(1-carboxyvinyl)oxy]benzoate + H2O + SAM ⟶ 6-amino-6-deoxyfutalosine + H+ + hydrogencarbonate + met - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + H2O ⟶ N-carbamoyl-L-aspartate + H+ - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of L-methionine salvage and degradation:
L-homocysteine + glycine betaine ⟶ N,N-dimethylglycine + met - ethylene biosynthesis V (engineered):
2-oxoglutarate + H+ + O2 ⟶ CO2 + H2O + ethene - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - mixed acid fermentation:
NAD+ + ethanol ⟶ H+ + NADH + acetaldehyde - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ (L-threonylcarbamoyl)adenylate + H2O + diphosphate - superpathway of arginine and polyamine biosynthesis:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - propanoyl CoA degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - inosine-5'-phosphate biosynthesis I:
ATP + CAIR + asp ⟶ ADP + H+ + SAICAR + phosphate - aspartate biosynthesis:
2-oxoglutarate + asp ⟶ glu + oxaloacetate - de novo biosynthesis of pyrimidine ribonucleotides:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
ATP + L-citrulline + asp ⟶ AMP + H+ + L-arginino-succinate + diphosphate - arginine biosynthesis:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis II:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - gluconeogenesis:
ATP + oxaloacetate ⟶ ADP + CO2 + phosphoenolpyruvate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis II (acetyl cycle):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + Glu + H+ + carbamoyl phosphate + phosphate - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + Glu + H+ + carbamoyl phosphate + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-glutamine biosynthesis III:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + Glu + H+ + carbamoyl phosphate + phosphate - urea cycle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + Glu + H+ + carbamoyl phosphate + phosphate - L-arginine biosynthesis I (via L-ornithine):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + Glu + H+ + carbamoyl phosphate + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + Glu + H+ + carbamoyl phosphate + phosphate - gluconeogenesis III:
ATP + hydrogencarbonate + pyruvate ⟶ ADP + H+ + oxaloacetate + phosphate - fatty acid biosynthesis -- elongase pathway:
an acyl-CoA + malonyl-CoA ⟶ CO2 + a 3-oxoacyl-CoA + coenzyme A - superpathway of sterol biosynthesis:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonia - leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glt - purine nucleotides de novo biosynthesis I:
adenylo-succinate ⟶ AMP + fumarate - inosine-5'-phosphate biosynthesis I:
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole ⟶ aminoimidazole carboxamide ribonucleotide + fumarate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - urea cycle:
ATP + L-citrulline + asp ⟶ AMP + H+ + L-arginino-succinate + diphosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis II:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
asp + carbamoyl-phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
asp + carbamoyl-phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - UMP biosynthesis:
asp + carbamoyl-phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - inosine-5'-phosphate biosynthesis I:
ATP + CAIR + asp ⟶ ADP + H+ + SAICAR + phosphate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - valine degradation I:
3-methyl-2-oxobutanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isobutanoyl-CoA - arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - uridine-5'-phosphate biosynthesis:
H+ + orotidine-5'-phosphate ⟶ CO2 + UMP - pyrimidine ribonucleotides de novo biosynthesis:
H+ + orotidine-5'-phosphate ⟶ CO2 + UMP - superpathway of arginine and polyamine biosynthesis:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis III:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis I:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - inosine-5'-phosphate biosynthesis I:
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole ⟶ aminoimidazole carboxamide ribonucleotide + fumarate - valine degradation I:
2-oxoisovalerate + NAD+ + coenzyme A ⟶ CO2 + NADH + isobutyryl-CoA - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - propanoyl CoA degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis I (via L-ornithine):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis II (acetyl cycle):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ (L-threonylcarbamoyl)adenylate + H2O + diphosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - propionyl CoA degradation:
ATP + hydrogen carbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - sitosterol degradation to androstenedione:
17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA ⟶ androst-4-ene-3,17-dione + propanoyl-CoA - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - UMP biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogen carbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - L-arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - 1,4-dihydroxy-6-naphthoate biosynthesis II:
6-amino-6-deoxyfutalosine + H2O ⟶ adenine + dehypoxanthine futalosine - superpathway of demethylmenaquinol-6 biosynthesis II:
6-amino-6-deoxyfutalosine + H2O ⟶ adenine + dehypoxanthine futalosine - UMP biosynthesis I:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
asp + carbamoyl phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - cyanate degradation:
H+ + bicarbonate + cyanate ⟶ CO2 + carbamate - UMP biosynthesis:
asp + carbamoyl-phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - inosine-5'-phosphate biosynthesis I:
ATP + CAIR + asp ⟶ ADP + H+ + SAICAR + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
asp + carbamoyl-phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
asp + carbamoyl-phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - valine degradation I:
3-methyl-2-oxobutanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isobutanoyl-CoA - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
asp + carbamoyl-phosphate ⟶ N-carbamoyl-L-aspartate + H+ + phosphate - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ 5-phospho-α-D-ribose 1-diphosphate + orotate - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis I:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ 5-phospho-α-D-ribose 1-diphosphate + orotate - leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glt - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ 5-phospho-α-D-ribose 1-diphosphate + orotate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - inosine-5'-phosphate biosynthesis I:
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole ⟶ 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate - methylmalonyl pathway:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - CO2 fixation into oxaloacetate (anapleurotic):
oxaloacetate + phosphate ⟶ bicarbonate + phosphoenolpyruvate - valine degradation I:
2-oxoglutarate + val ⟶ 3-methyl-2-oxobutanoate + glt - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - superpathway of purine nucleotides de novo biosynthesis II:
adenylo-succinate ⟶ AMP + fumarate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - formaldehyde assimilation I (serine pathway):
oxaloacetate + phosphate ⟶ hydrogen carbonate + phosphoenolpyruvate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogen carbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - mixed acid fermentation:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - propanoyl CoA degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis I (via L-ornithine):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - urea cycle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - propanoyl CoA degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - UMP biosynthesis II:
(S)-dihydroorotate + fumarate ⟶ orotate + succinate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - formaldehyde assimilation I (serine pathway):
CO2 + H+ + NADPH + acetyl-CoA + an oxidized electron-transfer flavoprotein ⟶ H+ + NADP+ + a reduced electron-transfer flavoprotein + coenzyme A + glyoxylate + propanoyl-CoA - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of methionine degradation:
S-adenosyl-L-homocysteine + H2O ⟶ L-homocysteine + adenosine - methylmalonyl pathway:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - isoleucine degradation:
2-oxoglutarate + ile ⟶ 2-keto-3-methyl-valerate + glt - Leucine Catabolism:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glt - aspartate biosynthesis:
2-oxoglutarate + asp ⟶ glt + oxaloacetate - valine degradation I:
2-oxoglutarate + val ⟶ 2-oxoisovalerate + glt - leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - uridine-5'-phosphate biosynthesis:
ATP + H2O + bicarbonate + gln ⟶ ADP + H+ + carbamoyl-phosphate + glt + phosphate - pyrimidine ribonucleotides de novo biosynthesis:
ATP + CDP ⟶ ADP + CTP - valine degradation:
2-oxoisovalerate + an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine ⟶ CO2 + an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine - leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glt - uridine-5'-phosphate biosynthesis:
ATP + H2O + bicarbonate + gln ⟶ ADP + H+ + carbamoyl-phosphate + glt + phosphate - pyrimidine ribonucleotides de novo biosynthesis:
ATP + UDP ⟶ ADP + H+ + UTP - pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + fumarate ⟶ orotate + succinate - aspartate biosynthesis II:
2-oxoglutarate + asp ⟶ glt + oxaloacetate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - valine degradation III:
H2O + NAD+ + coenzyme A + methylmalonate semialdehyde ⟶ H+ + NADH + hydrogen carbonate + propanoyl-CoA - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - cyanate degradation:
H+ + cyanate + hydrogen carbonate ⟶ CO2 + carbamate - aspartate threonine lysine biosynthesis superpathway:
2-oxoglutarate + asp ⟶ glt + oxaloacetate - leucine degradation IV:
H2O + NADP+ + leu ⟶ 4-methyl-2-oxopentanoate + NADPH + ammonia - formaldehyde assimilation I (serine pathway):
oxaloacetate + phosphate ⟶ hydrogen carbonate + phosphoenolpyruvate - propanoyl CoA degradation I:
ATP + hydrogen carbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - uridine-5'-phosphate biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - propanoyl CoA degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - 2-oxobutanoate degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - UMP biosynthesis III:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - propanoyl CoA degradation I:
ATP + hydrogen carbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogen carbonate + propanoyl-CoA - Methanobacterium thermoautotrophicum biosynthetic metabolism:
2-oxoglutarate + ala ⟶ glt + pyruvate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - superpathway of arginine and polyamine biosynthesis:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - gluconeogenesis II (Methanobacterium thermoautotrophicum):
NADP+ + formate ⟶ CO2 + NADPH - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glt - arginine biosynthesis I:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - itaconate biosynthesis:
citrate ⟶ cis-aconitate + H2O - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - uridine-5'-phosphate biosynthesis:
ATP + H2O + bicarbonate + gln ⟶ ADP + H+ + carbamoyl-phosphate + glt + phosphate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonia - pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + bicarbonate + gln ⟶ ADP + H+ + carbamoyl-phosphate + glt + phosphate - valine degradation I:
2-oxoisovalerate + NAD+ + coenzyme A ⟶ CO2 + NADH + isobutyryl-CoA - leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glt - urea cycle:
H2O + arg ⟶ L-ornithine + urea - cyanate degradation:
H+ + hydrogen carbonate ⟶ CO2 + H2O - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogen carbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of purine nucleotides de novo biosynthesis II:
adenylo-succinate ⟶ AMP + fumarate - UMP biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - UMP biosynthesis:
(S)-dihydroorotate + UQ ⟶ UQH2 + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + UQ ⟶ UQH2 + orotate - arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glt - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - cyanate degradation:
H+ + hydrogen carbonate ⟶ CO2 + H2O - superpathway of arginine and polyamine biosynthesis:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - cyanate degradation:
H+ + cyanate + hydrogen carbonate ⟶ CO2 + carbamate - arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - superpathway of arginine and polyamine biosynthesis:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - arginine biosynthesis I:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - gluconeogenesis I:
3-phospho-D-glycerate + ATP ⟶ 1,3-bisphospho-D-glycerate + ADP - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - uridine-5'-phosphate biosynthesis:
ATP + H2O + bicarbonate + gln ⟶ ADP + H+ + carbamoyl-phosphate + glt + phosphate - formaldehyde assimilation I (serine pathway):
ATP + D-glycerate ⟶ 2-phospho-D-glycerate + ADP + H+ - pyrimidine ribonucleotides de novo biosynthesis:
ATP + CMP ⟶ ADP + CDP - methylmalonyl pathway:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - arginine biosynthesis I:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - uridine-5'-phosphate biosynthesis:
(S)-dihydroorotate + UQ ⟶ UQH2 + orotate - formaldehyde assimilation I (serine pathway):
oxaloacetate + phosphate ⟶ bicarbonate + phosphoenolpyruvate - pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + UQ ⟶ UQH2 + orotate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - itaconate biosynthesis:
citrate ⟶ cis-aconitate + H2O - 3-hydroxypropionate/4-hydroxybutyrate cycle:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - sitosterol degradation to androstenedione:
NAD+ + sitosterol ⟶ 3-oxo-24-ethyl-cholest-5-ene + H+ + NADH - gluconeogenesis I:
3-phospho-D-glycerate + ATP ⟶ 1,3-bisphospho-D-glycerate + ADP - arginine biosynthesis I:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - pyrimidine ribonucleotides de novo biosynthesis:
ATP + CMP ⟶ ADP + CDP - C4 photosynthetic carbon assimilation cycle:
(S)-malate + NADP+ ⟶ H+ + NADPH + oxaloacetate - ethylbenzene degradation (anaerobic):
ATP + H2O + acetophenone + bicarbonate ⟶ 3-oxo-3-phenylpropanoate + ADP + H+ + phosphate - formaldehyde assimilation I (serine pathway):
ATP + D-glycerate ⟶ 2-phospho-D-glycerate + ADP + H+ - incomplete reductive TCA cycle:
2-oxoglutarate + an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A ⟶ CO2 + a reduced ferredoxin [iron-sulfur] cluster + succinyl-CoA - CO2 fixation into oxaloacetate (anapleurotic):
H+ + bicarbonate ⟶ CO2 + H2O - uridine-5'-phosphate biosynthesis:
ATP + H2O + bicarbonate + gln ⟶ ADP + H+ + carbamoyl-phosphate + glt + phosphate - methylmalonyl pathway:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - TCA cycle VI (obligate autotrophs):
H2O + NADP+ + glt ⟶ 2-oxoglutarate + H+ + NADPH + ammonia - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonia - leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - valine degradation I:
2-oxoglutarate + val ⟶ 2-oxoisovalerate + glt - 3-hydroxypropionate cycle:
ATP + bicarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - glutamine biosynthesis III:
ATP + ammonia + glt ⟶ ADP + gln + phosphate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - inosine-5'-phosphate biosynthesis I:
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole ⟶ aminoimidazole carboxamide ribonucleotide + fumarate - formaldehyde assimilation I (serine pathway):
oxaloacetate + phosphate ⟶ bicarbonate + phosphoenolpyruvate - respiration (anaerobic):
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - arginine biosynthesis I:
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine-5'-phosphate ⟶ 5-phospho-α-D-ribose 1-diphosphate + orotate - valine degradation I:
2-oxoglutarate + val ⟶ 3-methyl-2-oxobutanoate + glt - UMP biosynthesis:
diphosphate + orotidine-5'-phosphate ⟶ 5-phospho-α-D-ribose 1-diphosphate + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine-5'-phosphate ⟶ 5-phospho-α-D-ribose 1-diphosphate + orotate - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis II:
(S)-dihydroorotate + NAD+ ⟶ H+ + NADH + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - superpathway of histidine, purine and pyrimidine biosynthesis:
ATP + D-ribose 5-phosphate ⟶ 5-phosphoribosyl 1-pyrophosphate + AMP - arginine biosynthesis:
ATP + L-aspartate + citrulline ⟶ AMP + L-arginino-succinate + pyrophosphate - pyrimidine ribonucleotides de novo biosynthesis:
O2 + dihydroorotate ⟶ H2O2 + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - propionyl CoA degradation:
ATP + hydrogen carbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - propanoyl CoA degradation I:
ATP + hydrogen carbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - UMP biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogen carbonate + propanoyl-CoA - UMP biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogen carbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis III:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis III:
(S)-dihydroorotate + NAD+ ⟶ H+ + NADH + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - L-arginine biosynthesis III (via N-acetyl-L-citrulline):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogen carbonate ⟶ CO2 + H2O - UMP biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - inosine-5'-phosphate biosynthesis III:
SAICAR ⟶ AICAR + fumarate - incomplete reductive TCA cycle:
2-oxoglutarate + an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A ⟶ CO2 + H+ + a reduced ferredoxin [iron-sulfur] cluster + succinyl-CoA - L-arginine biosynthesis IV (archaebacteria):
2-oxoglutarate + a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-ornithyl)-L-glutamate ⟶ a [lysine-biosynthesis-protein LysW]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + glt - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glt - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
ATP + hydrogencarbonate + thr ⟶ H2O + L-threonylcarbamoyladenylate + diphosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - inosine-5'-phosphate biosynthesis I:
SAICAR ⟶ AICAR + fumarate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + Glu - mixed acid fermentation:
D-threo-isocitrate + NADP+ ⟶ 2-oxoglutarate + CO2 + NADPH
Plant Reactome(234)
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
Ac-CoA + H2O + OAA ⟶ CIT + CoA - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Inorganic nutrients metabolism:
Nitrite ⟶ H2O + ammonia - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H2O + carbon dioxide ⟶ HCO3- - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Inorganic nutrients metabolism:
ATP + L-Glu + ammonia ⟶ ADP + L-Gln + Pi - Cyanate catabolism:
H+ + HCO3- + cyanate ⟶ carbamate + carbon dioxide
INOH(0)
PlantCyc(1741)
- CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
2-oxoglutarate + ala ⟶ glu + pyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis I (via L-ornithine):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - gluconeogenesis III:
ATP + hydrogencarbonate + pyruvate ⟶ ADP + H+ + oxaloacetate + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-valine degradation I:
3-methyl-2-oxobutanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isobutanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - carbon concentration mechanism (Chlamydomonas):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis III:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - L-valine degradation I:
3-methyl-2-oxobutanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isobutanoyl-CoA - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis III:
(S)-dihydroorotate + NAD+ ⟶ H+ + NADH + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
L-arginino-succinate ⟶ arg + fumarate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
L-arginino-succinate ⟶ arg + fumarate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis II:
(S)-dihydroorotate + fumarate ⟶ orotate + succinate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis II:
(S)-dihydroorotate + fumarate ⟶ orotate + succinate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-valine degradation I:
3-methyl-2-oxobutanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isobutanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - urea cycle:
H2O + arg ⟶ L-ornithine + urea - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
2-oxoglutarate + ala ⟶ glu + pyruvate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of L-citrulline metabolism:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis I (via L-ornithine):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis II (acetyl cycle):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - carbon concentration mechanism (Chlamydomonas):
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - urea cycle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
2-oxoglutarate + val ⟶ 3-methyl-2-oxobutanoate + glu - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
2-oxoglutarate + ala ⟶ glu + pyruvate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-glutamine biosynthesis III:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - reductive TCA cycle I:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis III:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis II:
(S)-dihydroorotate + fumarate ⟶ orotate + succinate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis II:
(S)-dihydroorotate + fumarate ⟶ orotate + succinate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
2-oxoglutarate + leu ⟶ 4-methyl-2-oxopentanoate + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-leucine degradation I:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - UMP biosynthesis III:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - L-glutamine biosynthesis III:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - L-arginine biosynthesis I (via L-ornithine):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis II (acetyl cycle):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - cyanate degradation:
H+ + cyanate + hydrogencarbonate ⟶ CO2 + carbamate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - urea cycle:
H2O + arg ⟶ L-ornithine + urea - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - superpathway of L-citrulline metabolism:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-arginine biosynthesis I (via L-ornithine):
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
oxaloacetate + phosphate ⟶ hydrogencarbonate + phosphoenolpyruvate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - gluconeogenesis III:
D-glucopyranose 6-phosphate + H2O ⟶ D-glucopyranose + phosphate - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-arginine biosynthesis II (acetyl cycle):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - UMP biosynthesis I:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - urea cycle:
H2O + arg ⟶ L-ornithine + urea - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
H2O + acetyl-CoA + oxaloacetate ⟶ H+ + citrate + coenzyme A - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - L-arginine biosynthesis I (via L-ornithine):
2-oxoglutarate + N-acetyl-L-ornithine ⟶ N-acetyl-L-glutamate 5-semialdehyde + glu - L-leucine degradation I:
3-methylcrotonyl-CoA + ATP + hydrogencarbonate ⟶ 3-methylglutaconyl-CoA + ADP + H+ + phosphate - urea cycle:
H2O + arg ⟶ L-ornithine + urea - UMP biosynthesis I:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - cyanate degradation:
H+ + hydrogencarbonate ⟶ CO2 + H2O - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - L-arginine biosynthesis II (acetyl cycle):
N-acetyl-L-ornithine + glu ⟶ N-acetyl-L-glutamate + L-ornithine - CO2 fixation into oxaloacetate (anaplerotic):
H+ + hydrogencarbonate ⟶ CO2 + H2O - L-valine degradation I:
(S)-methylmalonate-semialdehyde + H2O + NAD+ + coenzyme A ⟶ H+ + NADH + hydrogencarbonate + propanoyl-CoA - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - biotin-carboxyl carrier protein assembly:
ATP + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + hydrogencarbonate ⟶ ADP + H+ + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + phosphate - ornithine-citrulline shuttle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + H2O + carbamoyl phosphate - L-glutamine biosynthesis III:
citrate ⟶ cis-aconitate + H2O - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - gluconeogenesis III:
ATP + hydrogencarbonate + pyruvate ⟶ ADP + H+ + oxaloacetate + phosphate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - ornithine-citrulline shuttle:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - UMP biosynthesis I:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis:
(L-threonylcarbamoyl)adenylate + an adenine37 in tRNA ⟶ AMP + H+ + an N6-L-threonylcarbamoyladenine37 in tRNA - superpathway of pyrimidine ribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - propanoyl CoA degradation I:
ATP + hydrogencarbonate + propanoyl-CoA ⟶ (S)-methylmalonyl-CoA + ADP + H+ + phosphate - gluconeogenesis III:
ATP + hydrogencarbonate + pyruvate ⟶ ADP + H+ + oxaloacetate + phosphate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
2-oxoglutarate + ala ⟶ glu + pyruvate - L-arginine biosynthesis II (acetyl cycle):
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - L-glutamine biosynthesis III:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - urea cycle:
ATP + ammonium + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + phosphate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + UTP + gln ⟶ ADP + CTP + H+ + glu + phosphate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, NAD-ME type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - cyanate degradation:
H+ + carbamate ⟶ CO2 + ammonium - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
ATP + phosphate + pyruvate ⟶ AMP + H+ + diphosphate + phosphoenolpyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, PEPCK type:
2-oxoglutarate + ala ⟶ glu + pyruvate - C4 photosynthetic carbon assimilation cycle, NADP-ME type:
(S)-malate + NADP+ ⟶ CO2 + NADPH + pyruvate - reductive TCA cycle I:
ATP + hydrogencarbonate + pyruvate ⟶ ADP + H+ + oxaloacetate + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate
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PathBank(251)
- Purine Nucleotides De Novo Biosynthesis:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Purine Nucleotides De Novo Biosynthesis:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Purine Nucleotides De Novo Biosynthesis:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Alanine Metabolism:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Metabolism:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Gluconeogenesis:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Primary Hyperoxaluria Type I:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Pyruvate Carboxylase Deficiency:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Lactic Acidemia:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Leigh Syndrome:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency):
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Dehydrogenase Complex Deficiency:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Transfer of Acetyl Groups into Mitochondria:
D-Glucose ⟶ Pyruvic acid - Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Congenital Lactic Acidosis:
Citric acid ⟶ Water + cis-Aconitic acid - Fumarase Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - Mitochondrial Complex II Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - 2-Ketoglutarate Dehydrogenase Complex Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Dehydrogenase Deficiency (E3):
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Dehydrogenase Deficiency (E2):
Citric acid ⟶ Water + cis-Aconitic acid - Primary Hyperoxaluria II, PH2:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Kinase Deficiency:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1):
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Fructose-1,6-diphosphatase Deficiency:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Triosephosphate Isomerase Deficiency:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Glycogenosis, Type IB:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Glycogenosis, Type IC:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Glycogenosis, Type IA. Von Gierke Disease:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Warburg Effect:
L-Glutamic acid + NAD + Water ⟶ Ammonia + NADH + Oxoglutaric acid - The Oncogenic Action of 2-Hydroxyglutarate:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - The Oncogenic Action of Succinate:
Citric acid ⟶ Water + cis-Aconitic acid - The Oncogenic Action of Fumarate:
Citric acid ⟶ Water + cis-Aconitic acid - Glutaminolysis and Cancer:
L-Glutamine ⟶ Ammonia + L-Glutamic acid - TCA Cycle:
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Metabolism:
2-Isopropylmalic acid + Coenzyme A ⟶ -Ketoisovaleric acid + Acetyl-CoA + Water - The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid - Alanine Metabolism:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Gluconeogenesis:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Pyruvate Metabolism:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Transfer of Acetyl Groups into Mitochondria:
D-Glucose ⟶ Pyruvic acid - Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Lactic Acidemia:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Leigh Syndrome:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Dehydrogenase Complex Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency):
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Carboxylase Deficiency:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Primary Hyperoxaluria Type I:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Congenital Lactic Acidosis:
Citric acid ⟶ Water + cis-Aconitic acid - Fumarase Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - Mitochondrial Complex II Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - 2-Ketoglutarate Dehydrogenase Complex Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Dehydrogenase Deficiency (E3):
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Dehydrogenase Deficiency (E2):
Citric acid ⟶ Water + cis-Aconitic acid - Primary Hyperoxaluria II, PH2:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Kinase Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1):
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Fructose-1,6-diphosphatase Deficiency:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Triosephosphate Isomerase Deficiency:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Glycogenosis, Type IB:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Glycogenosis, Type IC:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Glycogenosis, Type IA. Von Gierke Disease:
Glucose 1-phosphate + Water ⟶ D-Glucose + Phosphate - Warburg Effect:
L-Glutamic acid + NAD + Water ⟶ Ammonia + NADH + Oxoglutaric acid - Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid - Alanine Metabolism:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Gluconeogenesis:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Pyruvate Metabolism:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Transfer of Acetyl Groups into Mitochondria:
L-Malic acid + NAD ⟶ Hydrogen Ion + NADH + Oxalacetic acid - Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid - Alanine Metabolism:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Gluconeogenesis:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Pyruvate Metabolism:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Transfer of Acetyl Groups into Mitochondria:
L-Malic acid + NAD ⟶ Hydrogen Ion + NADH + Oxalacetic acid - Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid - Alanine Metabolism:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Pyruvate Metabolism:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Transfer of Acetyl Groups into Mitochondria:
L-Malic acid + NAD ⟶ Hydrogen Ion + NADH + Oxalacetic acid - Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - Citric Acid Cycle:
Citric acid ⟶ Water + cis-Aconitic acid - Alanine Metabolism:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Pyruvate Metabolism:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Transfer of Acetyl Groups into Mitochondria:
L-Malic acid + NAD ⟶ Hydrogen Ion + NADH + Oxalacetic acid - Warburg Effect:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - The Oncogenic Action of 2-Hydroxyglutarate:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - Glutaminolysis and Cancer:
L-Glutamine ⟶ Ammonia + L-Glutamic acid - The Oncogenic Action of 2-Hydroxyglutarate:
L-Glutamine + Water ⟶ Ammonia + L-Glutamic acid - Glutaminolysis and Cancer:
L-Glutamine ⟶ Ammonia + L-Glutamic acid - Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Lactic Acidemia:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Leigh Syndrome:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Dehydrogenase Complex Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency):
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Carboxylase Deficiency:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Primary Hyperoxaluria Type I:
Adenosine triphosphate + L-Alanine ⟶ Adenosine monophosphate + Pyrophosphate - Congenital Lactic Acidosis:
Citric acid ⟶ Water + cis-Aconitic acid - Fumarase Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - Mitochondrial Complex II Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - 2-Ketoglutarate Dehydrogenase Complex Deficiency:
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Dehydrogenase Deficiency (E3):
Citric acid ⟶ Water + cis-Aconitic acid - Pyruvate Dehydrogenase Deficiency (E2):
Citric acid ⟶ Water + cis-Aconitic acid - Primary Hyperoxaluria II, PH2:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Kinase Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1):
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Fructose-1,6-diphosphatase Deficiency:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Triosephosphate Isomerase Deficiency:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Glycogenosis, Type IB:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Glycogenosis, Type IC:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Glycogenosis, Type IA. Von Gierke Disease:
-D-Glucose + Adenosine triphosphate ⟶ -D-Glucose 6-phosphate + Adenosine diphosphate - Citrate Cycle:
Isocitric acid ⟶ Water + cis-Aconitic acid - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Arginine Metabolism:
N-Acetylornithine + Water ⟶ Acetic acid + Ornithine - Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water - Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water - Arginine Metabolism:
N-Acetylornithine + Water ⟶ Acetic acid + Ornithine - Proline Metabolism:
N-Acetylornithine + Water ⟶ Acetic acid + Ornithine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Arginine Metabolism:
N-Acetylornithine + Water ⟶ Acetic acid + Ornithine - Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water - Valine, Leucine, and Isoleucine Degradation:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - beta-Ketothiolase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - 2-Methyl-3-hydroxybutyryl-CoA Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Propionic Acidemia:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Maple Syrup Urine Disease:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - 3-Methylglutaconic Aciduria Type I:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - 3-Methylglutaconic Aciduria Type III:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Methylmalonate Semialdehyde Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Methylmalonic Aciduria:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Isovaleric Aciduria:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Malonic Aciduria:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Methylmalonic Aciduria Due to Cobalamin-Related Disorders:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - 3-Methylglutaconic Aciduria Type IV:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Malonyl-CoA Decarboxylase Deficiency:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - 3-Hydroxyisobutyric Aciduria:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Isobutyryl-CoA Dehydrogenase Deficiency:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Isovaleric Acidemia:
-Ketoisovaleric acid + Thiamine pyrophosphate ⟶ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide - Valine Degradation:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Valine, Leucine, and Isoleucine Degradation:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylglutaconic Aciduria Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylglutaconic Aciduria Type III:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylglutaconic Aciduria Type IV:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - beta-Ketothiolase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Isovaleric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Malonic Aciduria:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Maple Syrup Urine Disease:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Methylmalonate Semialdehyde Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Methylmalonic Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Methylmalonic Aciduria Due to Cobalamin-Related Disorders:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Propionic Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Malonyl-CoA Decarboxylase Deficiency:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Hydroxyisobutyric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Isobutyryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Isovaleric Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Valine, Leucine, and Isoleucine Degradation:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Valine, Leucine, and Isoleucine Degradation:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Propanoate Metabolism:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylglutaconic Aciduria Type I:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylglutaconic Aciduria Type III:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Methylglutaconic Aciduria Type IV:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - beta-Ketothiolase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Isovaleric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Malonic Aciduria:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Maple Syrup Urine Disease:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Methylmalonate Semialdehyde Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Methylmalonic Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Methylmalonic Aciduria Due to Cobalamin-Related Disorders:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Propionic Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Malonyl-CoA Decarboxylase Deficiency:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - 3-Hydroxyisobutyric Aciduria:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Isobutyryl-CoA Dehydrogenase Deficiency:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Isovaleric Acidemia:
L-Valine + Oxoglutaric acid ⟶ -Ketoisovaleric acid + L-Glutamic acid - Palmitate Biosynthesis:
Hydrogen Ion + NADPH + acetoacetyl-[acp] ⟶ (R)-3-hydroxybutanoyl-[acp] + NADP - Fatty Acid Elongation (Saturated):
3-oxoacyl-[acp] + Hydrogen Ion + NADPH ⟶ (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP - Fatty Acid Biosynthesis:
3-oxoacyl-[acp] + Hydrogen Ion + NADPH ⟶ (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP - Palmitate Biosynthesis 2:
Hydrogen Ion + NADPH + acetoacetyl-[acp] ⟶ (R)-3-hydroxybutanoyl-[acp] + NADP - Palmitate Biosynthesis:
Acetyl-CoA + Adenosine triphosphate + Hydrogen carbonate ⟶ Adenosine diphosphate + Hydrogen Ion + Malonyl-CoA + Phosphate - Fatty Acid Elongation (Saturated):
Acetyl-CoA + Adenosine triphosphate + Hydrogen carbonate ⟶ Adenosine diphosphate + Hydrogen Ion + Malonyl-CoA + Phosphate - Fatty Acid Biosynthesis:
Acetyl-CoA + Adenosine triphosphate + Hydrogen carbonate ⟶ Adenosine diphosphate + Hydrogen Ion + Malonyl-CoA + Phosphate - Palmitate Biosynthesis 2:
Acetyl-CoA + Adenosine triphosphate + Hydrogen carbonate ⟶ Adenosine diphosphate + Hydrogen Ion + Malonyl-CoA + Phosphate - Glutamine Metabolism:
Adenosine triphosphate + Phosphate + Pyruvic acid ⟶ Adenosine monophosphate + Hydrogen Ion + Phosphoenolpyruvic acid + Pyrophosphate - Threonine and 2-Oxobutanoate Degradation:
L-Threonine ⟶ 2-Ketobutyric acid + Ammonia - Esomeprazole Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Omeprazole Action Pathway:
Hydrogen + Omeprazole ⟶ Active Metabolite of Omeprazole - Lansoprazole Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Pantoprazole Action Pathway:
Hydrogen + Pantoprazole ⟶ Active Metabolite of Pantoprazole - Rabeprazole Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Ranitidine Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Famotidine Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Cimetidine Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Nizatidine Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Pirenzepine Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Gastric Acid Production:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Roxatidine Acetate Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Metiamide Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Betazole Action Pathway:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Nitrogen Metabolism:
Ammonia + Hydrogen + NADPH + Oxoglutaric acid ⟶ L-Glutamic acid + NADP + Water - Purine Nucleotides De Novo Biosynthesis 2:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Propanoyl-CoA Degradation:
Adenosine triphosphate + Hydrogen carbonate + Propionyl-CoA ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + S-Methylmalonyl-CoA - Biotin-Carboxyl Carrier Protein Assembly:
Adenosine triphosphate + Biotin + Biotin-Carboxyl Carrying Protein ⟶ Adenosine monophosphate + Biotinylated [BCCP monomer] + Hydrogen Ion + Pyrophosphate - Cyanate Degradation:
Carbon dioxide + Water ⟶ Hydrogen Ion + Hydrogen carbonate - Leucine Degradation:
3-Hydroxy-3-methylglutaryl-CoA ⟶ Acetoacetic acid + Acetyl-CoA - Lafutidine H2-Antihistamine Action:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Threonine and 2-Oxobutanoate Degradation:
2-Ketobutyric acid + Coenzyme A + NAD ⟶ NADH + Propionyl-CoA - Gastric Acid Production:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Gastric Acid Production:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Gastric Acid Production:
Adenosine triphosphate + Hydrogen Ion + Potassium + Water ⟶ Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium - Kidney Function- Proximal Convoluted Tubule:
Carbon dioxide + Water ⟶ Hydrogen Ion + Hydrogen carbonate - Kidney Function - Collecting Duct:
Carbon dioxide + Water ⟶ Hydrogen Ion + Hydrogen carbonate - Nitrogen Metabolism:
Carbamic acid + Hydrogen Ion ⟶ Ammonia + Carbon dioxide - Purine Nucleotides De Novo Biosynthesis 2:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Biotin-Carboxyl Carrier Protein Assembly:
Adenosine triphosphate + Biotin + Biotin-Carboxyl Carrying Protein ⟶ Adenosine monophosphate + Biotinylated [BCCP monomer] + Hydrogen Ion + Pyrophosphate - Cyanate Degradation:
Cyanate + Hydrogen Ion + Hydrogen carbonate ⟶ Carbamic acid + Carbon dioxide
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jiawen Chen. Transportation for fuel: Thylakoid membrane bestrophin channels facilitate HCO3- transport to the pyrenoid in diatoms.
Plant physiology.
2024 May; 195(2):1108-1110. doi:
10.1093/plphys/kiae133. [PMID: 38445821] - Haiying Lv, Yu Cao, Jin Zhu, Qing Liang. Molecular Insights into the Effect of Cholesterol on the Binding of Bicarbonate Ions in Band 3 Protein.
Langmuir : the ACS journal of surfaces and colloids.
2024 May; 40(21):10908-10915. doi:
10.1021/acs.langmuir.4c00216. [PMID: 38739034] - Nicolas Chéron. Binding Sites of Bicarbonate in Phosphoenolpyruvate Carboxylase.
Journal of chemical information and modeling.
2024 Apr; 64(8):3375-3385. doi:
10.1021/acs.jcim.3c01830. [PMID: 38533570] - Carolin Magdalene Heise, Martin Hagemann, Hendrik Schubert. Photosynthetic response of Chara braunii towards different bicarbonate concentrations.
Physiologia plantarum.
2024 Mar; 176(2):e14234. doi:
10.1111/ppl.14234. [PMID: 38439180] - Nimrit Goraya, Donald E Wesson. Pathophysiology of Diet-Induced Acid Stress.
International journal of molecular sciences.
2024 Feb; 25(4):. doi:
10.3390/ijms25042336. [PMID: 38397012] - Sebastià Capó-Bauçà, Concepción Iñiguez, Jeroni Galmés. The diversity and coevolution of Rubisco and CO2 concentrating mechanisms in marine macrophytes.
The New phytologist.
2024 Jan; ?(?):. doi:
10.1111/nph.19528. [PMID: 38197185] - Priya Gahlowt, Durgesh Kumar Tripathi, Samiksha Singh, Ravi Gupta, Vijay Pratap Singh. Does MPK4/12-HT1 function as a CO2/bicarbonate sensor to regulate the stomatal conductance under high CO2 levels?.
Plant cell reports.
2023 Dec; 42(12):2043-2045. doi:
10.1007/s00299-023-03077-8. [PMID: 37815540] - Silvia Busoms, Laura Pérez-Martín, Joana Terés, Xin-Yuan Huang, Levi Yant, Roser Tolrà, David E Salt, Charlotte Poschenrieder. Combined genomics to discover genes associated with tolerance to soil carbonate.
Plant, cell & environment.
2023 Dec; 46(12):3986-3998. doi:
10.1111/pce.14691. [PMID: 37565316] - Sai Krishna Talla, Bobba Sunil, Duvvarapu Easwar Rao, Pidakala Rajsheel, Deepak Saini, Agepati S Raghavendra. Redox basis of photosynthesis inhibition at supra-optimal bicarbonate in mesophyll protoplasts of Arabidopsis thaliana.
Journal of plant physiology.
2023 Aug; 287(?):154047. doi:
10.1016/j.jplph.2023.154047. [PMID: 37393886] - Maura Greiser, Mariusz Karbowski, Aaron David Kaplan, Andrew Kyle Coleman, Nicolas Verhoeven, Carmen A Mannella, W Jonathan Lederer, Liron Boyman. Calcium and bicarbonate signaling pathways have pivotal, resonating roles in matching ATP production to demand.
eLife.
2023 Jun; 12(?):. doi:
10.7554/elife.84204. [PMID: 37272417] - Andrea Fantuzzi, Patrycja Haniewicz, Domenica Farci, M Cecilia Loi, Keunha Park, Claudia Büchel, Matthias Bochtler, A William Rutherford, Dario Piano. Bicarbonate Activation of the Monomeric Photosystem II-PsbS/Psb27 Complex.
Plant physiology.
2023 May; ?(?):. doi:
10.1093/plphys/kiad275. [PMID: 37202365] - Wei Liu, Jichao Tang, Dahong Zhang, Xun Jiang, Bilin Lu, Wenjia Yang. Improvement of straw decomposition and rice growth through co-application of straw-decomposing inoculants and ammonium nitrogen fertilizer.
BMC plant biology.
2023 May; 23(1):244. doi:
10.1186/s12870-023-04254-3. [PMID: 37158844] - A Domínguez García, C Centeno Álvarez, J Muñoz Rodríguez, T Bonfill Abella, M Capdevila Gonzalo, L de Verdonces Roman, O Mayordomo Ferrer, P Azuara Invernon, E Casado Burgos, J Prats López, X Serra Aracil. Prevalence of metabolic acidosis in ileal diversions more than one year after radical cystectomy and associated secondary metabolic effects.
Actas urologicas espanolas.
2023 Apr; ?(?):. doi:
10.1016/j.acuroe.2023.04.010. [PMID: 37086841] - Britta Förster, Loraine M Rourke, Hiruni N Weerasooriya, Isaiah C M Pabuayon, Vivien Rolland, Eng Kee Au, Soumi Bala, Joanna Bajsa-Hirschel, Sarah Kaines, Remmy Kasili, Lillian LaPlace, Marylou C Machingura, Baxter Massey, Viviana C Rosati, Hilary Stuart-Williams, Murray R Badger, G Dean Price, James V Moroney. The Chlamydomonas reinhardtii chloroplast envelope protein LCIA transports bicarbonate in planta.
Journal of experimental botany.
2023 Mar; ?(?):. doi:
10.1093/jxb/erad116. [PMID: 36987927] - Khaled A Selim, Michael Haffner, Oliver Mantovani, Reinhard Albrecht, Hongbo Zhu, Martin Hagemann, Karl Forchhammer, Marcus D Hartmann. Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA.
Proceedings of the National Academy of Sciences of the United States of America.
2023 Feb; 120(8):e2205882120. doi:
10.1073/pnas.2205882120. [PMID: 36800386] - Ezequias Castillo-Lopez, Cátia Pacífico, Arife Sener-Aydemir, Karin Hummel, Katharina Nöbauer, Sara Ricci, Raul Rivera-Chacon, Nicole Reisinger, Ebrahim Razzazi-Fazeli, Qendrim Zebeli, Susanne Kreuzer-Redmer. Diet and phytogenic supplementation substantially modulate the salivary proteome in dairy cows.
Journal of proteomics.
2023 02; 273(?):104795. doi:
10.1016/j.jprot.2022.104795. [PMID: 36535624] - Hong-Sik Hwang, Jill K Winkler-Moser. Bicarbonates and carbonates as antioxidants in vegetable oils at frying temperatures.
Journal of food science.
2023 Feb; 88(2):717-731. doi:
10.1111/1750-3841.16442. [PMID: 36576154] - Samantha R Wray, Puja P Patel, Christopher D Jackson. Mind the gap: A case of unexplained elevated anion gap without concomitant metabolic acidosis.
Journal of the National Medical Association.
2023 Feb; 115(1):77-80. doi:
10.1016/j.jnma.2022.11.002. [PMID: 36535807] - Yuanlei Chen, Wenwu Bao, Weijin Hong, Xiaoke Dong, Manyu Gong, Quanqi Cheng, Ke Mao, Chunchao Yao, Zhande Liu, Nannan Wang. Evaluation of eleven kiwifruit genotypes for bicarbonate tolerance and characterization of two tolerance-contrasting genotypes.
Plant physiology and biochemistry : PPB.
2023 Jan; 194(?):202-213. doi:
10.1016/j.plaphy.2022.11.017. [PMID: 36427382] - Monika Wieliczko, Jolanta Małyszko. Acid-base balance in hemodialysis patients in everyday practice.
Renal failure.
2022 Dec; 44(1):1090-1097. doi:
10.1080/0886022x.2022.2094805. [PMID: 35793495] - Jia-Liang Zhu, Hui Liu, Li-Li Wang, Xue-Hao Lu, Hai-Yan Yin, Jun Lyu, Jian-Rui Wei. Association of lactate to albumin ratio and bicarbonate with short-term mortality risk in patients with acute myocardial infarction.
BMC cardiovascular disorders.
2022 11; 22(1):490. doi:
10.1186/s12872-022-02902-4. [PMID: 36401181] - Krystyna Maslowska-Jarzyna, Alessio Cataldo, Anna Marszalik, Ilona Ignatikova, Stephen J Butler, Radosław Stachowiak, Michał J Chmielewski, Hennie Valkenier. Dissecting transmembrane bicarbonate transport by 1,8-di(thio)amidocarbazoles.
Organic & biomolecular chemistry.
2022 10; 20(38):7658-7663. doi:
10.1039/d2ob01461k. [PMID: 36134504] - Nikita Misella Hansen, Peder Berg, Marianne Rix, Manan Pareek, Jens Leipziger, Anne-Lise Kamper, Arne Astrup, Mads Vaarby Sorensen, Louise Salomo. The New Nordic Renal Diet Induces a Pronounced Reduction of Urine Acid Excretion and Uremic Toxins in Chronic Kidney Disease Patients (Stage 3 and 4).
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
2022 Oct; ?(?):. doi:
10.1053/j.jrn.2022.09.010. [PMID: 36195272] - Kien Lam Ung, Mikael Winkler, Lukas Schulz, Martina Kolb, Dorina P Janacek, Emil Dedic, David L Stokes, Ulrich Z Hammes, Bjørn Panyella Pedersen. Structures and mechanism of the plant PIN-FORMED auxin transporter.
Nature.
2022 09; 609(7927):605-610. doi:
10.1038/s41586-022-04883-y. [PMID: 35768502] - Shimrit Tzvi-Behr, Alon Bnaya, Rachel Becker-Cohen, Choni Rinat, Jenny Weinbrand-Goichberg, Sapir Choshen, Linda Shavit, Yaacov Frishberg, Efrat Ben-Shalom. Metabolic alkalosis in infants treated with peritoneal dialysis.
Pediatric nephrology (Berlin, Germany).
2022 Aug; 37(8):1889-1895. doi:
10.1007/s00467-021-05344-w. [PMID: 35039929] - Dongun Lee, Peter Chang-Whan Lee, Jeong Hee Hong, Dong Min Shin. Estrogen treatment reduced oxalate transporting activity and enhanced migration through the involvement of SLC26A6 in lung cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA.
2022 Aug; 82(?):105373. doi:
10.1016/j.tiv.2022.105373. [PMID: 35500753] - Klara R Klein, Schafer C Boeder, Jennifer L R Freeman, Imogene Dunn, Chris Dvergsten, Supradeep Madduri, Erin R Giovannetti, Carmen Valcarce, John B Buse, Jeremy H Pettus. Impact of the hepatoselective glucokinase activator TTP399 on ketoacidosis during insulin withdrawal in people with type 1 diabetes.
Diabetes, obesity & metabolism.
2022 08; 24(8):1439-1447. doi:
10.1111/dom.14697. [PMID: 35661378] - A H W Koks, C Fritz, A J P Smolders, K Rehlmeyer, J T M Elzenga, S Krosse, L P M Lamers, G van Dijk. Sphagnum bleaching: Bicarbonate 'toxicity' and tolerance for seven Sphagnum species.
Plant biology (Stuttgart, Germany).
2022 Aug; 24(5):780-790. doi:
10.1111/plb.13423. [PMID: 35340103] - Batric Babovic, Srdjan Djuranovic, Olgica Mihaljevic, Katarina Sakic, Jelena Borovinic Bojovic, Irena Radoman Vujacic, Natasa Belada Babovic, Vladimir Jovanovic, Vasilije Boskovic, Snezana Radovanovic. Dyspepsia in Montenegrin chronic kidney disease patients undergoing hemodialysis: endoscopic and histopathological features.
International urology and nephrology.
2022 Aug; 54(8):1891-1897. doi:
10.1007/s11255-021-03075-3. [PMID: 34837575] - Michele A Rodrigues, Dawidson A Gomes, Romina Fiorotto, Mateus T Guerra, Jittima Weerachayaphorn, Tao Bo, William C Sessa, Mario Strazzabosco, Michael H Nathanson. Molecular determinants of peri-apical targeting of inositol 1,4,5-trisphosphate receptor type 3 in cholangiocytes.
Hepatology communications.
2022 Jul; ?(?):. doi:
10.1002/hep4.2042. [PMID: 35852334] - C Thongprayoon, A G Kattah, M A Mao, M T Keddis, P Pattharanitima, S Vallabhajosyula, V Nissaisorakarn, S B Erickson, J J Dillon, V D Garovic, W Cheungpasitporn. Distinct phenotypes of hospitalized patients with hyperkalemia by machine learning consensus clustering and associated mortality risks.
QJM : monthly journal of the Association of Physicians.
2022 Jul; 115(7):442-449. doi:
10.1093/qjmed/hcab194. [PMID: 34270780] - Onur Cil, Tifany Chu, Sujin Lee, Peter M Haggie, Alan S Verkman. Small-molecule inhibitor of intestinal anion exchanger SLC26A3 for treatment of hyperoxaluria and nephrolithiasis.
JCI insight.
2022 07; 7(13):. doi:
10.1172/jci.insight.153359. [PMID: 35608921] - Ei Phyo Khaing, Victor Zhong, Sandeesha Kodru, Imre Vass, Julian J Eaton-Rye. Tyr244 of the D2 Protein Is Required for Correct Assembly and Operation of the Quinone-Iron-Bicarbonate Acceptor Complex of Photosystem II.
Biochemistry.
2022 07; 61(13):1298-1312. doi:
10.1021/acs.biochem.2c00164. [PMID: 35699437] - Y R Jiang, M Wang, J L Wan, G F Zhang, H P Yang, Q Li. [Genotype-phenotype analysis and prognosis in children with primary distal renal tubular acidosis].
Zhonghua er ke za zhi = Chinese journal of pediatrics.
2022 Jul; 60(7):700-705. doi:
10.3760/cma.j.cn112140-20211212-01036. [PMID: 35768359] - Lokesh N Shah, Matthew B Matheson, Susan L Furth, George J Schwartz, Bradley A Warady, Cynthia J Wong. Low variability of plant protein intake in the CKiD cohort does not demonstrate changes in estimated GFR nor electrolyte balance.
Pediatric nephrology (Berlin, Germany).
2022 07; 37(7):1647-1655. doi:
10.1007/s00467-021-05334-y. [PMID: 34796391] - Arzu Ozdemir, Sibel Yucel Kocak, Suheyla Apaydın, Murvet Yılmaz. Daily variability of acid-base status and determinants of serum bicarbonate in hemodialysis patients.
Clinical nephrology.
2022 Jul; 98(1):26-32. doi:
10.5414/cn110735. [PMID: 35343436] - Jaswin S Sawhney, George Kasotakis, Anna Goldenberg, Stuart Abramson, Christopher Dodgion, Nimitt Patel, Mansoor Khan, John J Como. Management of rhabdomyolysis: A practice management guideline from the Eastern Association for the Surgery of Trauma.
American journal of surgery.
2022 07; 224(1 Pt A):196-204. doi:
10.1016/j.amjsurg.2021.11.022. [PMID: 34836603] - Wenhui Chen, Jie Guo, Yalun Liang, Xiaotao Zhang, Shuwen Jiang, Ruixiang Hu, Wah Yang, Cunchuan Wang, Zhiyong Dong. Obesity hypoventilation syndrome in bariatric surgery patients: an underestimated disease.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.
2022 07; 18(7):894-901. doi:
10.1016/j.soard.2022.02.017. [PMID: 35644806] - Moustafa Moustafa, Rasha D Sawaya, Zavi Lakissian, Rana Sharara-Chami. The Association Between Initial Serum Bicarbonate Levels and the Management of Dehydrated Children in the Emergency Department: A Retrospective Review.
Pediatric emergency care.
2022 Jul; 38(7):e1396-e1401. doi:
10.1097/pec.0000000000002570. [PMID: 34772877] - Darren M Roberts, Robert S Hoffman, Jeffrey Brent, Valéry Lavergne, Knut Erik Hovda, William H Porter, Kenneth E McMartin, Marc Ghannoum. The serum glycolate concentration: its prognostic value and its correlation to surrogate markers in ethylene glycol exposures.
Clinical toxicology (Philadelphia, Pa.).
2022 07; 60(7):798-807. doi:
10.1080/15563650.2022.2049811. [PMID: 35323087] - Yang-Yang He, Yi Yan, Ji-Wang Chen, Sheng Liu, Lu Hua, Xin Jiang, Xi-Qi Xu, Dan Lu, Zhi-Cheng Jing, Fu-Xia Yan, Zhi-Yan Han. Plasma metabolomics in the perioperative period of defect repair in patients with pulmonary arterial hypertension associated with congenital heart disease.
Acta pharmacologica Sinica.
2022 Jul; 43(7):1710-1720. doi:
10.1038/s41401-021-00804-3. [PMID: 34848852] - Han Wu, Shiyong Liu, Pan Su, Zhang-Dong Xie, Tian-Xiang Gui, Lei Zhao, Ying Liu, Li-Ming Chen. Molecular insight into coordination sites for substrates and their coupling kinetics in Na+ /HCO3 - cotransporter NBCe1.
The Journal of physiology.
2022 Jul; 600(13):3083-3111. doi:
10.1113/jp282034. [PMID: 35156711] - Janna R Raphelson, Christopher N Schmickl, Christine Sonners, Kimberly Kreitinger, Eduardo Grunvald, Santiago Horgan, Atul Malhotra. Obesity Hypoventilation Syndrome and Postsurgical Outcomes in a Bariatric Surgery Cohort.
Obesity surgery.
2022 07; 32(7):1-7. doi:
10.1007/s11695-022-06073-1. [PMID: 35538187] - Michelle M Y Wong, Dani Renouf, Yuyan Zheng, Zainab Sheriff, Adeera Levin. Nutritional Status, Nutritional Phenotypes, and Oral Nutritional Supplement Prescription Patterns Among Patients With Non-Dialysis Chronic Kidney Disease in British Columbia.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
2022 Jul; 32(4):414-422. doi:
10.1053/j.jrn.2021.08.011. [PMID: 34924262] - Vandana S Mathur, Elizabeth Li, Donald E Wesson. Effects of veverimer on serum bicarbonate and physical function in diabetic patients with chronic kidney disease and metabolic acidosis: subgroup analysis from a randomized, controlled trial.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2022 06; 37(7):1302-1309. doi:
10.1093/ndt/gfab209. [PMID: 34240198] - Ariadna Delgado-Bermúdez, Marc Yeste, Sergi Bonet, Elisabeth Pinart. A Review on the Role of Bicarbonate and Proton Transporters during Sperm Capacitation in Mammals.
International journal of molecular sciences.
2022 Jun; 23(11):. doi:
10.3390/ijms23116333. [PMID: 35683013] - Jim Q Ho, Joe Verghese, Matthew K Abramowitz. Serum bicarbonate levels and gait abnormalities in older adults: a cross-sectional study.
Scientific reports.
2022 Jun; 12(1):9171. doi:
10.1038/s41598-022-12907-w. [PMID: 35654910] - Francisco José Borrego Utiel, Isidoro Herrera Contreras, Enoc Merino García, Clara Moriana Domínguez, Esther Ocaña Pérez, Maria José García Cortés. Hypocitraturia is present when renal function is impaired in diverse nephropathies and is not related with serum bicarbonate levels.
International urology and nephrology.
2022 Jun; 54(6):1261-1269. doi:
10.1007/s11255-021-02992-7. [PMID: 34546556] - C Warnar, E Faber, P A Katinakis, T Schermer, P E Spronk. Electrolyte monitoring during regional citrate anticoagulation in continuous renal replacement therapy.
Journal of clinical monitoring and computing.
2022 Jun; 36(3):871-877. doi:
10.1007/s10877-021-00719-8. [PMID: 33991270] - Antong Xia, Yanyou Wu. Joint interactions of carbon and nitrogen metabolism dominated by bicarbonate and nitrogen in Orychophragmus violaceus and Brassica napus under simulated karst habitats.
BMC plant biology.
2022 May; 22(1):264. doi:
10.1186/s12870-022-03646-1. [PMID: 35619072] - N Mammadova, J Soukup, P Shkodivskyi, C Gudowski, A Ahmed, R U Pliquett. A patient with severe metformin-associated lactic acidosis complicated by acute coronary syndrome: a case report.
BMC nephrology.
2022 05; 23(1):174. doi:
10.1186/s12882-022-02781-z. [PMID: 35524187] - Asim Muhammad, Muhammad Hakim, Saima Afaq, Farhad Ali Khattak, Najmush Shakireen, Muhammad Jawad, Rabia Saeed, Zia Ul Haq. Diabetic ketoacidosis amongst patients with COVID-19: A retrospective chart review of 220 patients in Pakistan.
Endocrinology, diabetes & metabolism.
2022 05; 5(3):e00331. doi:
10.1002/edm2.331. [PMID: 35212184] - Denver D Brown, Megan Carroll, Derek K Ng, Rebecca V Levy, Larry A Greenbaum, Frederick J Kaskel, Susan L Furth, Bradley A Warady, Michal L Melamed, Andrew Dauber. Longitudinal Associations between Low Serum Bicarbonate and Linear Growth in Children with CKD.
Kidney360.
2022 04; 3(4):666-676. doi:
10.34067/kid.0005402021. [PMID: 35721607] - Kata Csekő, Dóra Hargitai, Lilla Draskóczi, Adrienn Kéri, Pongsiri Jaikumpun, Beáta Kerémi, Zsuzsanna Helyes, Ákos Zsembery. Safety of chronic hypertonic bicarbonate inhalation in a cigarette smoke-induced airway irritation guinea pig model.
BMC pulmonary medicine.
2022 Apr; 22(1):131. doi:
10.1186/s12890-022-01919-x. [PMID: 35392868] - Katarzyna Szczecińska, Małgorzata Wajdlich, Maja Nowicka, Michał Nowicki, Ilona Kurnatowska. Effects of Oral Bicarbonate Supplementation on the Cardiovascular Risk Factors and Serum Nutritional Markers in Non-Dialysed Chronic Kidney Disease Patients.
Medicina (Kaunas, Lithuania).
2022 Apr; 58(4):. doi:
10.3390/medicina58040518. [PMID: 35454357] - Haris Ahmad, Theresa Wertin, Yilin Zhang, Jon O Neher, Beth Auten. Is bicarbonate therapy effective in preventing CKD progression?.
The Journal of family practice.
2022 04; 71(3):E15-E16. doi:
10.12788/jfp.0377. [PMID: 35561240] - Rafał Nowicki, Mikołaj Berezowski, Julita Kulbacka, Katarzyna Bieżuńska-Kusiak, Marek Jasiński, Jolanta Saczko. Custodiol HTK versus Plegisol: in-vitro comparison with the use of immature (H9C2) and mature (HCM) cardiomyocytes cultures.
BMC cardiovascular disorders.
2022 03; 22(1):108. doi:
10.1186/s12872-022-02536-6. [PMID: 35296256] - Hirotaka Fukasawa, Mai Kaneko, Yuri Uchiyama, Hideo Yasuda, Ryuichi Furuya. Lower bicarbonate level is associated with CKD progression and all-cause mortality: a propensity score matching analysis.
BMC nephrology.
2022 03; 23(1):86. doi:
10.1186/s12882-022-02712-y. [PMID: 35246054] - Jason C Siegler, Amelia J Carr, William T Jardine, Lilia Convit, Rebecca Cross, Dale Chapman, Louise M Burke, Megan Ross. The Hyperhydration Potential of Sodium Bicarbonate and Sodium Citrate.
International journal of sport nutrition and exercise metabolism.
2022 03; 32(2):74-81. doi:
10.1123/ijsnem.2021-0179. [PMID: 34875625] - Robert Boland-Freitas, James H Lee, Karl Ng. Serum electrolyte concentrations and skeletal muscle excitability in vivo.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.
2022 03; 135(?):13-21. doi:
10.1016/j.clinph.2021.12.008. [PMID: 35007839] - Osama A Gheith, Mohammed Dahab, Ayman Maher Nagib, Mohamed Adel, Nabil Elserwy, Islam Sobhy, Mohamed AbdelMonem, Hasaneen Abo Atya, Torki Al-Otaibi. Fludrocortisone Among Adult Renal Transplant Recipients With Persistent Hyperkalemia: Single-Center Experience.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2022 03; 20(Suppl 1):69-73. doi:
10.6002/ect.mesot2021.o27. [PMID: 35384810] - Anna Wiegand, Sandar Felicity Lim, Seraina von Moos, Rudolf Peter Wüthrich, Leonhard Held, Nilufar Mohebbi. Association of serum bicarbonate with graft survival and mortality in kidney transplant recipients.
Journal of nephrology.
2022 Mar; 35(2):619-627. doi:
10.1007/s40620-021-01197-6. [PMID: 34843097] - Anab Rebecca Lehr, Soha Rached-d'Astous, Nick Barrowman, Anne Tsampalieros, Melissa Parker, Lauralyn McIntyre, Margaret Sampson, Kusum Menon. Balanced Versus Unbalanced Fluid in Critically Ill Children: Systematic Review and Meta-Analysis.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.
2022 03; 23(3):181-191. doi:
10.1097/pcc.0000000000002890. [PMID: 34991134] - Nisha Yadav, Neha Gupta, D P Singh. Ameliorating Effect of Bicarbonate on Salinity Induced Changes in the Growth, Nutrient Status, Cell Constituents and Photosynthetic Attributes of Microalga Chlorella vulgaris.
Bulletin of environmental contamination and toxicology.
2022 Mar; 108(3):491-499. doi:
10.1007/s00128-021-03135-5. [PMID: 33594450] - Ines Pankonien, Margarida C Quaresma, Cláudia S Rodrigues, Margarida D Amaral. CFTR, Cell Junctions and the Cytoskeleton.
International journal of molecular sciences.
2022 Feb; 23(5):. doi:
10.3390/ijms23052688. [PMID: 35269829] - Vandana S Mathur, Donald E Wesson, Navdeep Tangri, Elizabeth Li, David A Bushinsky. Effects of veverimer on serum bicarbonate and physical function in women with chronic kidney disease and metabolic acidosis: a subgroup analysis from a randomised, controlled trial.
BMC nephrology.
2022 02; 23(1):82. doi:
10.1186/s12882-022-02690-1. [PMID: 35216581] - Peder Berg, Jesper Frank Andersen, Mads Vaarby Sørensen, Tobias Wang, Hans Malte, Jens Leipziger. Alkalosis-induced hypoventilation in cystic fibrosis: The importance of efficient renal adaptation.
Proceedings of the National Academy of Sciences of the United States of America.
2022 02; 119(8):. doi:
10.1073/pnas.2116836119. [PMID: 35173044] - Grazia Tamma, Silvia Dossena. Functional interplay between CFTR and pendrin: physiological and pathophysiological relevance.
Frontiers in bioscience (Landmark edition).
2022 02; 27(2):75. doi:
10.31083/j.fbl2702075. [PMID: 35227018] - Andrea Fantuzzi, Friederike Allgöwer, Holly Baker, Gemma McGuire, Wee Kii Teh, Ana P Gamiz-Hernandez, Ville R I Kaila, A William Rutherford. Bicarbonate-controlled reduction of oxygen by the QA semiquinone in Photosystem II in membranes.
Proceedings of the National Academy of Sciences of the United States of America.
2022 02; 119(6):. doi:
10.1073/pnas.2116063119. [PMID: 35115403] - John K Leypoldt, Mauro Pietribiasi, Jorge Echeverri, Kai Harenski. Modeling acid-base balance during continuous kidney replacement therapy.
Journal of clinical monitoring and computing.
2022 02; 36(1):179-189. doi:
10.1007/s10877-020-00635-3. [PMID: 33389356] - Rachel D Heisler, Jordan J Kelly, Sara Abedinzadegan Abdi, Jennifer L Hawker, Leanne G Fong, Janet L Quon, Josee Z Rioux, Jennifer C Jupp. Evaluation of an oral sodium bicarbonate protocol for high-dose methotrexate urine alkalinization.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2022 Feb; 30(2):1273-1281. doi:
10.1007/s00520-021-06503-3. [PMID: 34471970] - Hisato Shima, Takuya Okamoto, Tomoko Inoue, Manabu Tashiro, Yusaku Tanaka, Norimichi Takamatsu, Seiichiro Wariishi, Kazuhiko Kawahara, Kazuyoshi Okada, Jun Minakuchi. A complicated case of Serratia marcescens catheter-related bloodstream infection misdiagnosed as hypersensitivity reactions to bicarbonate dialysate containing acetate.
CEN case reports.
2022 02; 11(1):55-59. doi:
10.1007/s13730-021-00624-8. [PMID: 34302598] - Emine Can, Jessica A M Bastiaansen, Dominique-Laurent Couturier, Rolf Gruetter, Hikari A I Yoshihara, Arnaud Comment. [13C]bicarbonate labelled from hyperpolarized [1-13C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state.
Communications biology.
2022 01; 5(1):10. doi:
10.1038/s42003-021-02978-2. [PMID: 35013537] - Kristin George, Ashish Datt Upadhyay, Arun Kumar Subbiah, Raj Kanwar Yadav, Sandeep Mahajan, Dipankar Bhowmik, Sanjay Kumar Agarwal, Soumita Bagchi. Metabolic acidosis in the initial 6 months after renal transplantation: A prospective study.
Nephrology (Carlton, Vic.).
2022 Jan; 27(1):90-96. doi:
10.1111/nep.13954. [PMID: 34302717] - Anne M Murray, Yelena Slinin, David E Tupper, Sarah L Pederson, Cynthia Davey, David T Gilbertson, Paul Drawz, Ryan Mello, Allyson Hart, Kirsten L Johansen, Scott Reule, Rebecca Rossom, David S Knopman. Kidney-Metabolic Factors Associated with Cognitive Impairment in Chronic Kidney Disease: A Pilot Study.
American journal of nephrology.
2022; 53(6):435-445. doi:
10.1159/000524166. [PMID: 35483332] - S V Skupnevskii, F E Batagova, E G Pukhaeva, A K Badtiev, F K Rurua, Zh G Farnieva. [The effect of natural mineral bicarbonate sodium-calcium water «Tib-1» on the antioxidant status of rats with adjuvant rheumatoid arthritis].
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury.
2022; 99(3):41-49. doi:
10.17116/kurort20229903141. [PMID: 35700375] - Miguel Belaunzaran, Shahm Raslan, Aleeza Ali, Kevin Newsome, Mark McKenney, Adel Elkbuli. Utilization and Efficacy of Resuscitation Endpoints in Trauma and Burn Patients: A Review Article.
The American surgeon.
2022 Jan; 88(1):10-19. doi:
10.1177/00031348211060424. [PMID: 34761698] - Ken-Ei Sada, Ryohei Yamamoto, Akihiko Yano, Atsushi Miyauchi, Masafumi Kawamura, Hideki Ito. Bicarbonate concentration as a predictor of prognosis in moderately severe COVID-19 patients: A multicenter retrospective study.
PloS one.
2022; 17(6):e0270141. doi:
10.1371/journal.pone.0270141. [PMID: 35749694] - Pedro H Imenez Silva, Robert Unwin, Ewout J Hoorn, Alberto Ortiz, Francesco Trepiccione, Rikke Nielsen, Vesna Pesic, Gaye Hafez, Denis Fouque, Ziad A Massy, Chris I De Zeeuw, Giovambattista Capasso, Carsten A Wagner. Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2021 12; 37(Suppl 2):ii4-ii12. doi:
10.1093/ndt/gfab216. [PMID: 34718761] - Charles J Blijdorp, David Severs, Usha M Musterd-Bhaggoe, Ronald T Gansevoort, Robert Zietse, Ewout J Hoorn. Serum bicarbonate is associated with kidney outcomes in autosomal dominant polycystic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2021 12; 36(12):2248-2255. doi:
10.1093/ndt/gfaa283. [PMID: 33377160] - Secil Deniz, Tugba Kevser Uysal, Clemente Capasso, Claudiu T Supuran, Ozen Ozensoy Guler. Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection?.
Journal of enzyme inhibition and medicinal chemistry.
2021 Dec; 36(1):1230-1235. doi:
10.1080/14756366.2021.1924165. [PMID: 34074197] - Nilgun Salk Vatandas, Kadriye Yurdakok, Siddika Songul Yalcin, Melda Celik. Validity Analysis on the Findings of Dehydration in 2 to 24-Month-Old Children With Acute Diarrhea.
Pediatric emergency care.
2021 Dec; 37(12):e1227-e1232. doi:
10.1097/pec.0000000000001980. [PMID: 31913251] - S Kayhan, B Selcan Akyol, M Ergul, C Baysan. The effect of type of fluid on disease severity in acute pancreatitis treatment.
European review for medical and pharmacological sciences.
2021 Dec; 25(23):7460-7467. doi:
10.26355/eurrev_202112_27443. [PMID: 34919248] - Thamer A Alsufayan, Evan J Myers, Bianca N Quade, Clayton T Brady, Aniko Marshall, Nayem Haque, Michael E Duffey, Mark D Parker. Revisiting the Role of Ser982 Phosphorylation in Stoichiometry Shift of the Electrogenic Na+/qHCO3- Cotransporter NBCe1.
International journal of molecular sciences.
2021 Nov; 22(23):. doi:
10.3390/ijms222312817. [PMID: 34884619] - Lotte Bonde Bertelsen, Esben Søvsø Szocska Hansen, Thorsten Sadowski, Sven Ruf, Christoffer Laustsen. Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney.
NMR in biomedicine.
2021 11; 34(11):e4583. doi:
10.1002/nbm.4583. [PMID: 34240478] - Matthew B Wolf. Mechanisms of Acid-Base Kinetics During Hemodialysis: a Mathematical-Model Study.
ASAIO journal (American Society for Artificial Internal Organs : 1992).
2021 11; 67(11):1263-1267. doi:
10.1097/mat.0000000000001366. [PMID: 33512837] - Katsuhiro Matsuura, Tomohiko Yoshida, Takuya Uehara, Shusaku Yamada, Hideki Yotsuida, Mizuki Hasegawa, Sakie Katayose, Kurumi Yamada, Youta Yaginuma. Metabolic alkalosis following mitral valvuloplasty in a dog with preoperative acute kidney injury.
Journal of the American Veterinary Medical Association.
2021 11; 259(11):1332-1336. doi:
10.2460/javma.20.09.0519. [PMID: 34727063] - Marco Marano, Deepak Jain, H K Aggarwal, Francesco Izzo. Evaluation of Expected Ventilatory Response to Metabolic Acidosis in Severely Ill Patients.
The Journal of the Association of Physicians of India.
2021 Nov; 69(11):11-12. doi:
NULL. [PMID: 34781612] - Emmanuel A Adomako, Saira Bilal, Yu-Lun Liu, Ayesha Malik, Peter N Van Buren, Shani Shastri, Kamalanathan K Sambandam. Idiopathic Hypokalemia in Lupus Nephritis: A Newly Recognized Entity.
Kidney360.
2021 10; 2(10):1553-1559. doi:
10.34067/kid.0004352021. [PMID: 35372968] - Yoshinori Marunaka, Katsumi Yagi, Noboru Imagawa, Hironori Kobayashi, Masaru Murayama, Asami Minamibata, Yoshiaki Takanashi, Takashi Nakahari. Possibility of Venous Serum Cl- Concentration ([Cl-]s) as a Marker for Human Metabolic Status: Correlation of [Cl-]s to Age, Fasting Blood Sugar (FBS), and Glycated Hemoglobin (HbA1c).
International journal of molecular sciences.
2021 Oct; 22(20):. doi:
10.3390/ijms222011111. [PMID: 34681771] - Chon In Kuok, Winnie Kwai Yu Chan. Acute kidney injury in pediatric non-traumatic rhabdomyolysis.
Pediatric nephrology (Berlin, Germany).
2021 10; 36(10):3251-3257. doi:
10.1007/s00467-021-05057-0. [PMID: 33851263] - Nancy S Krieger, David A Bushinsky. Metabolic acidosis regulates RGS16 and G protein signaling in osteoblasts.
American journal of physiology. Renal physiology.
2021 10; 321(4):F424-F430. doi:
10.1152/ajprenal.00166.2021. [PMID: 34396788] - Charat Thongprayoon, Pradeep Vaitla, Voravech Nissaisorakarn, Michael A Mao, Jose L Zabala Genovez, Andrea G Kattah, Pattharawin Pattharanitima, Saraschandra Vallabhajosyula, Mira T Keddis, Fawad Qureshi, John J Dillon, Vesna D Garovic, Kianoush B Kashani, Wisit Cheungpasitporn. Clinically Distinct Subtypes of Acute Kidney Injury on Hospital Admission Identified by Machine Learning Consensus Clustering.
Medical sciences (Basel, Switzerland).
2021 09; 9(4):. doi:
10.3390/medsci9040060. [PMID: 34698185] - He Liu, Zheng Zhang, Jiaxin Li, Wanyu Zang, Qing Yang, Jun Yang. Fabrication of gelatin microspheres containing ammonium hydrogen carbonate for the tunable release of herbicide.
Biotechnology letters.
2021 Sep; 43(9):1747-1755. doi:
10.1007/s10529-021-03163-5. [PMID: 34275026] - Stanley M H Yeung, Antonio W Gomes-Neto, Maryse C J Osté, Else van den Berg, Jenny E Kootstra-Ros, Jan Stephan F Sanders, Stefan P Berger, Juan Jesus Carrero, Martin H De Borst, Gerjan J Navis, Stephan J L Bakker. Net Endogenous Acid Excretion and Kidney Allograft Outcomes.
Clinical journal of the American Society of Nephrology : CJASN.
2021 09; 16(9):1398-1406. doi:
10.2215/cjn.00780121. [PMID: 34135022] - Sebastian Hultin, David W Johnson, Sunil V Badve. Recent evidence on the effect of treatment of metabolic acid on the progression of kidney disease.
Current opinion in nephrology and hypertension.
2021 09; 30(5):467-473. doi:
10.1097/mnh.0000000000000728. [PMID: 34009141] - Ravindra V Badhe, Sonali S Nipate. The use of negative oxygen ion clusters [O2-(H2O)n] and bicarbonate ions [HCO3-] as the supportive treatment of COVID-19 infections: A possibility.
Medical hypotheses.
2021 Sep; 154(?):110658. doi:
10.1016/j.mehy.2021.110658. [PMID: 34390895] - Erica Memoli, Pietro B Faré, Pietro Camozzi, Giacomo D Simonetti, Mario G Bianchetti, Sebastiano A Lava, Gregorio P Milani. Trimethoprim-associated electrolyte and acid-base abnormalities.
Minerva medica.
2021 Aug; 112(4):500-505. doi:
10.23736/s0026-4806.20.06660-4. [PMID: 32697061] - Donald E Wesson. The Continuum of Acid Stress.
Clinical journal of the American Society of Nephrology : CJASN.
2021 08; 16(8):1292-1299. doi:
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