Guanosine diphosphate mannose (BioDeep_00000415787)

Main id: BioDeep_00000001755

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


Guanosine diphosphate mannose

化学式: C16H25N5O16P2 (605.0771510000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OC4C(C(C(C(O4)CO)O)O)O)O)O)N=C(NC2=O)N
InChI: InChI=1S/C16H25N5O16P2/c17-16-19-12-6(13(28)20-16)18-3-21(12)14-10(26)8(24)5(34-14)2-33-38(29,30)37-39(31,32)36-15-11(27)9(25)7(23)4(1-22)35-15/h3-5,7-11,14-15,22-27H,1-2H2,(H,29,30)(H,31,32)(H3,17,19,20,28)/t4-,5-,7-,8-,9+,10-,11+,14-,15-/m1/s1

描述信息

同义名列表

1 个代谢物同义名

Guanosine diphosphate mannose



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(4)

PlantCyc(2)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Naho Nishigaki, Yoshihisa Yoshimi, Hiroaki Kuki, Tadashi Kunieda, Ikuko Hara-Nishimura, Yoichi Tsumuraya, Daisuke Takahashi, Paul Dupree, Toshihisa Kotake. Galactoglucomannan structure of Arabidopsis seed-coat mucilage in GDP-mannose synthesis impaired mutants. Physiologia plantarum. 2021 Nov; 173(3):1244-1252. doi: 10.1111/ppl.13519. [PMID: 34380178]
  • Chunmei Yu, Ming Yan, Huizhen Dong, Jie Luo, Yongchao Ke, Anfang Guo, Yanhong Chen, Jian Zhang, Xiaosan Huang. Maize bHLH55 functions positively in salt tolerance through modulation of AsA biosynthesis by directly regulating GDP-mannose pathway genes. Plant science : an international journal of experimental plant biology. 2021 Jan; 302(?):110676. doi: 10.1016/j.plantsci.2020.110676. [PMID: 33288001]
  • Robert Howlett, Katri Anttonen, Nicholas Read, Margaret C M Smith. Disruption of the GDP-mannose synthesis pathway in Streptomyces coelicolor results in antibiotic hyper-susceptible phenotypes. Microbiology (Reading, England). 2018 04; 164(4):614-624. doi: 10.1099/mic.0.000636. [PMID: 29493491]
  • Thomas F T Rexer, Anna Schildbach, Jan Klapproth, Angelika Schierhorn, Reza Mahour, Markus Pietzsch, Erdmann Rapp, Udo Reichl. One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides. Biotechnology and bioengineering. 2018 Jan; 115(1):192-205. doi: 10.1002/bit.26454. [PMID: 28922469]
  • Pengyan Zhang, Zhanru Shao, Weihua Jin, Delin Duan. Comparative characterization of two GDP-mannose dehydrogenase genes from Saccharina japonica (Laminariales, Phaeophyceae). BMC plant biology. 2016 Mar; 16(?):62. doi: 10.1186/s12870-016-0750-3. [PMID: 26956020]
  • Shota Sawake, Noriaki Tajima, Jenny C Mortimer, Jeemeng Lao, Toshiki Ishikawa, Xiaolan Yu, Yukiko Yamanashi, Yoshihisa Yoshimi, Maki Kawai-Yamada, Paul Dupree, Yoichi Tsumuraya, Toshihisa Kotake. KONJAC1 and 2 Are Key Factors for GDP-Mannose Generation and Affect l-Ascorbic Acid and Glucomannan Biosynthesis in Arabidopsis. The Plant cell. 2015 Dec; 27(12):3397-409. doi: 10.1105/tpc.15.00379. [PMID: 26672069]
  • Jenny C Mortimer, Xiaolan Yu, Sandra Albrecht, Francesca Sicilia, Mariela Huichalaf, Diego Ampuero, Louise V Michaelson, Alex M Murphy, Toshiro Matsunaga, Samantha Kurz, Elaine Stephens, Timothy C Baldwin, Tadashi Ishii, Johnathan A Napier, Andreas P M Weber, Michael G Handford, Paul Dupree. Abnormal glycosphingolipid mannosylation triggers salicylic acid-mediated responses in Arabidopsis. The Plant cell. 2013 May; 25(5):1881-94. doi: 10.1105/tpc.113.111500. [PMID: 23695979]
  • Sílvia A Sousa, Joana R Feliciano, Pedro F Pinheiro, Jorge H Leitão. Biochemical and functional studies on the Burkholderia cepacia complex bceN gene, encoding a GDP-D-mannose 4,6-dehydratase. PloS one. 2013; 8(2):e56902. doi: 10.1371/journal.pone.0056902. [PMID: 23460819]
  • Jakob Engel, Philipp S Schmalhorst, Françoise H Routier. Biosynthesis of the fungal cell wall polysaccharide galactomannan requires intraluminal GDP-mannose. The Journal of biological chemistry. 2012 Dec; 287(53):44418-24. doi: 10.1074/jbc.m112.398321. [PMID: 23139423]
  • Sabine Kuettel, Majken C T Wadum, Maria Lucia S Güther, Karina Mariño, Carolin Riemer, Michael A J Ferguson. The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei. Molecular microbiology. 2012 Apr; 84(2):340-51. doi: 10.1111/j.1365-2958.2012.08026.x. [PMID: 22375793]
  • Chase F Kempinski, Rawaa Haffar, Carina Barth. Toward the mechanism of NH(4) (+) sensitivity mediated by Arabidopsis GDP-mannose pyrophosphorylase. Plant, cell & environment. 2011 May; 34(5):847-58. doi: 10.1111/j.1365-3040.2011.02290.x. [PMID: 21332510]
  • Michael Kämpf, Birgit Absmanner, Markus Schwarz, Ludwig Lehle. Biochemical characterization and membrane topology of Alg2 from Saccharomyces cerevisiae as a bifunctional alpha1,3- and 1,6-mannosyltransferase involved in lipid-linked oligosaccharide biosynthesis. The Journal of biological chemistry. 2009 May; 284(18):11900-12. doi: 10.1074/jbc.m806416200. [PMID: 19282279]
  • Frank A Hoeberichts, Elke Vaeck, Guy Kiddle, Emmy Coppens, Brigitte van de Cotte, Antoine Adamantidis, Sandra Ormenese, Christine H Foyer, Marc Zabeau, Dirk Inzé, Claire Périlleux, Frank Van Breusegem, Marnik Vuylsteke. A Temperature-sensitive mutation in the Arabidopsis thaliana phosphomannomutase gene disrupts protein glycosylation and triggers cell death. The Journal of biological chemistry. 2008 Feb; 283(9):5708-18. doi: 10.1074/jbc.m704991200. [PMID: 18086684]
  • Floriana Fruscione, Laura Sturla, Garry Duncan, James L Van Etten, Paola Valbuzzi, Antonio De Flora, Eleonora Di Zanni, Michela Tonetti. Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses. The Journal of biological chemistry. 2008 Jan; 283(1):184-193. doi: 10.1074/jbc.m706614200. [PMID: 17974560]
  • Hairong Huang, Michael S Scherman, Wim D'Haeze, Danny Vereecke, Marcelle Holsters, Dean C Crick, Michael R McNeil. Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis. The Journal of biological chemistry. 2005 Jul; 280(26):24539-43. doi: 10.1074/jbc.m504068200. [PMID: 15878857]
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  • B Kneidinger, M Graninger, G Adam, M Puchberger, P Kosma, S Zayni, P Messner. Identification of two GDP-6-deoxy-D-lyxo-4-hexulose reductases synthesizing GDP-D-rhamnose in Aneurinibacillus thermoaerophilus L420-91T. The Journal of biological chemistry. 2001 Feb; 276(8):5577-83. doi: 10.1074/jbc.m010027200. [PMID: 11096116]
  • J S Rush, K Panneerselvam, C J Waechter, H H Freeze. Mannose supplementation corrects GDP-mannose deficiency in cultured fibroblasts from some patients with Congenital Disorders of Glycosylation (CDG). Glycobiology. 2000 Aug; 10(8):829-35. doi: 10.1093/glycob/10.8.829. [PMID: 10929009]
  • P L Conklin, S R Norris, G L Wheeler, E H Williams, N Smirnoff, R L Last. Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 1999 Mar; 96(7):4198-203. doi: 10.1073/pnas.96.7.4198. [PMID: 10097187]
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  • Adrián A Vojnov, Angeles Zorreguieta, J Maxwell Dow, Michael J Daniels, Marcelo A Dankert. Evidence for a role for the gumB and gumC gene products in the formation of xanthan from its pentasaccharide repeating unit by Xanthomonas campestris. Microbiology (Reading, England). 1998 Jun; 144 ( Pt 6)(?):1487-1493. doi: 10.1099/00221287-144-6-1487. [PMID: 9639919]
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  • G S Besra, C B Morehouse, C M Rittner, C J Waechter, P J Brennan. Biosynthesis of mycobacterial lipoarabinomannan. The Journal of biological chemistry. 1997 Jul; 272(29):18460-6. doi: 10.1074/jbc.272.29.18460. [PMID: 9218490]
  • J L Kadrmas, K A Brozek, C R Raetz. Lipopolysaccharide core glycosylation in Rhizobium leguminosarum. An unusual mannosyl transferase resembling the heptosyl transferase I of Escherichia coli. The Journal of biological chemistry. 1996 Dec; 271(50):32119-25. doi: . [PMID: 8943265]
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