ST 22:3;O3 (BioDeep_00000409800)

Main id: BioDeep_00000002308

Secondary id: BioDeep_00000001664, BioDeep_00000402585, BioDeep_00001867849


代谢物信息卡片


(6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione

化学式: C22H32O3 (344.2351)
中文名称: 丙酸睾丸素, 甲羟孕酮, 甲孕酮
谱图信息: 最多检出来源 Homo sapiens(plant) 2.79%

分子结构信息

SMILES: C1C[C@@](C(=O)C)(O)[C@@]2(C)CC[C@]3([H])[C@@]4(C)CCC(=O)C=C4[C@@H](C)C[C@@]3([H])[C@@]21[H]
InChI: InChI=1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1

描述信息

CONFIDENCE standard compound; INTERNAL_ID 1391; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10301; ORIGINAL_PRECURSOR_SCAN_NO 10299
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
CONFIDENCE standard compound; INTERNAL_ID 1391; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10334; ORIGINAL_PRECURSOR_SCAN_NO 10329
CONFIDENCE standard compound; INTERNAL_ID 1391; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10348; ORIGINAL_PRECURSOR_SCAN_NO 10343
CONFIDENCE standard compound; INTERNAL_ID 1391; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10391; ORIGINAL_PRECURSOR_SCAN_NO 10386
CONFIDENCE standard compound; INTERNAL_ID 1391; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10401; ORIGINAL_PRECURSOR_SCAN_NO 10399
CONFIDENCE standard compound; INTERNAL_ID 1391; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10415; ORIGINAL_PRECURSOR_SCAN_NO 10413
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03A - Hormonal contraceptives for systemic use > G03AC - Progestogens
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03D - Progestogens > G03DA - Pregnen (4) derivatives
L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02A - Hormones and related agents > L02AB - Progestogens
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
CONFIDENCE standard compound; INTERNAL_ID 2395
INTERNAL_ID 2395; CONFIDENCE standard compound

同义名列表

14 个代谢物同义名

17-propionyl-17beta-hydroxyandrost-4-en-3-one; Testosterone propionate; ST 22:3;O3; (6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione; 17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione; 6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione; 17alpha-Hydroxy-6alpha-methylprogesterone; 6alpha-Methyl-17alpha-hydroxyprogesterone; 17-Hydroxy-6alpha-methylprogesterone; medroxyprogesterone; Medroxyprogesteron; Testosterone propionate; Medroxyprogesterone; Medroxyprogesterone



数据库引用编号

42 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AKR1C3, ANG, CLU, ERBB2, HSD3B2, PGR, PIK3C3, POMC, VDR
Peripheral membrane protein 2 CLU, CYP21A2
Endosome membrane 1 ERBB2
Endoplasmic reticulum membrane 3 CYP21A2, HSD3B2, HSP90B1
Mitochondrion membrane 1 CLU
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 7 AKR1C3, ANG, CLU, ERBB2, HSP90B1, PGR, VDR
autophagosome 1 PIK3C3
cytosol 9 AKR1C3, ANG, CLU, ERBB2, HSP90B1, PGR, PIK3C3, SST, VDR
mitochondrial membrane 2 CLU, HSD3B2
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
nucleoplasm 4 ERBB2, PGR, TMPRSS2, VDR
RNA polymerase II transcription regulator complex 1 VDR
Cell membrane 2 ERBB2, TMPRSS2
Cytoplasmic side 1 CLU
ruffle membrane 1 ERBB2
Synapse 1 CLU
cell surface 3 ADIPOQ, CLU, EPO
glutamatergic synapse 1 PIK3C3
Golgi apparatus 1 CLU
growth cone 1 ANG
lysosomal membrane 1 EGF
mitochondrial inner membrane 2 CLU, HSD3B2
neuromuscular junction 1 ERBB2
neuronal cell body 2 ANG, SST
presynaptic membrane 1 ERBB2
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 CLU
endosome 1 PIK3C3
plasma membrane 5 EGF, ERBB2, PGR, REN, TMPRSS2
Membrane 8 CYP21A2, EGF, ERBB2, HSD3B2, HSP90B1, PIK3C3, REN, TMPRSS2
apical plasma membrane 1 ERBB2
basolateral plasma membrane 1 ERBB2
extracellular exosome 6 AKR1C3, CLU, EGF, EPO, HSP90B1, TMPRSS2
endoplasmic reticulum 4 ADIPOQ, CLU, HSD3B2, HSP90B1
extracellular space 10 ADIPOQ, ANG, CLU, CRP, EGF, EPO, IGF1, POMC, REN, SST
perinuclear region of cytoplasm 3 CLU, ERBB2, HSP90B1
mitochondrion 1 CLU
protein-containing complex 2 CLU, HSP90B1
intracellular membrane-bounded organelle 2 CLU, HSD3B2
Microsome membrane 1 CYP21A2
Single-pass type I membrane protein 1 ERBB2
Secreted 9 ADIPOQ, ANG, CLU, CRP, EPO, IGF1, POMC, REN, SST
extracellular region 13 ADIPOQ, ANG, CLU, CRP, EGF, EPO, ERBB2, HSP90B1, IGF1, POMC, REN, SST, TMPRSS2
Single-pass membrane protein 2 CYP21A2, HSD3B2
mitochondrial outer membrane 1 PGR
actin cytoskeleton 1 ANG
cytoplasmic vesicle 1 ERBB2
nucleolus 2 ANG, HSD3B2
midbody 2 HSP90B1, PIK3C3
Early endosome 1 ERBB2
apical part of cell 1 REN
Single-pass type II membrane protein 1 TMPRSS2
Cell projection, ruffle membrane 1 ERBB2
Cytoplasm, perinuclear region 2 CLU, ERBB2
focal adhesion 1 HSP90B1
GABA-ergic synapse 2 PIK3C3, SST
Peroxisome 1 PIK3C3
basement membrane 1 ANG
collagen trimer 1 ADIPOQ
mitochondrial intermembrane space 1 HSD3B2
collagen-containing extracellular matrix 3 ADIPOQ, CLU, HSP90B1
secretory granule 1 POMC
axoneme 1 PIK3C3
Late endosome 1 PIK3C3
receptor complex 2 ERBB2, VDR
chromatin 2 PGR, VDR
phagocytic vesicle membrane 1 PIK3C3
Chromosome 1 ANG
Nucleus, nucleolus 1 ANG
blood microparticle 1 CLU
intercellular bridge 1 HSD3B2
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
Melanosome 1 HSP90B1
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
Smooth endoplasmic reticulum membrane 1 HSD3B2
cell body 1 EPO
myelin sheath 1 ERBB2
sperm plasma membrane 1 HSP90B1
basal plasma membrane 1 ERBB2
[Isoform 4]: Cytoplasm 1 CLU
exocytic vesicle 1 IGF1
Microsome 1 CLU
secretory granule lumen 2 EPO, POMC
endoplasmic reticulum lumen 1 HSP90B1
platelet alpha granule lumen 3 CLU, EGF, IGF1
endocytic vesicle 1 ANG
presynaptic endosome 1 PIK3C3
neuronal dense core vesicle 1 SST
semaphorin receptor complex 1 ERBB2
clathrin-coated endocytic vesicle membrane 1 EGF
Sarcoplasmic reticulum lumen 1 HSP90B1
[Transmembrane protease serine 2 catalytic chain]: Secreted 1 TMPRSS2
apical dendrite 1 CLU
[Isoform 1]: Cell membrane 1 ERBB2
postsynaptic endosome 1 PIK3C3
spherical high-density lipoprotein particle 1 CLU
endocytic vesicle lumen 1 HSP90B1
[Isoform 1]: Secreted 1 CLU
Autolysosome 1 PIK3C3
angiogenin-PRI complex 1 ANG
ERBB3:ERBB2 complex 1 ERBB2
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
[Isoform 4]: Mitochondrion outer membrane 1 PGR
neurofibrillary tangle 1 CLU
endoplasmic reticulum chaperone complex 1 HSP90B1
Cytoplasmic vesicle, secretory vesicle, chromaffin granule 1 CLU
chromaffin granule 1 CLU
[Isoform 6]: Cytoplasm 1 CLU
perinuclear endoplasmic reticulum lumen 1 CLU


文献列表

  • Shedrach C Kanu, Fidelis E Ejezie, Chioma S Ejezie, Chinedum O Eleazu. Effect of methanol extract of Plectranthus esculentus N.E.Br tuber and its fractions on indices of benign prostatic hyperplasia in Wistar rats. Journal of ethnopharmacology. 2024 Sep; 331(?):118301. doi: 10.1016/j.jep.2024.118301. [PMID: 38735419]
  • Young-Jin Choi, Nishala Erandi Wedamulla, Seok-Hee Kim, Mirae Oh, Kang Sik Seo, Jeong Su Han, Eun Joo Lee, Young Ho Park, Young Jin Park, Eun-Kyung Kim. Salvia miltiorrhiza Bunge Ameliorates Benign Prostatic Hyperplasia through Regulation of Oxidative Stress via Nrf-2/HO-1 Activation. Journal of microbiology and biotechnology. 2024 May; 34(5):1059-1072. doi: 10.4014/jmb.2308.08053. [PMID: 37994101]
  • Seong Min Lee, Sang Mok Lee, Jungbin Song. Effects of Taraxaci Herba (Dandelion) on Testosterone Propionate-Induced Benign Prostatic Hyperplasia in Rats. Nutrients. 2024 Apr; 16(8):. doi: 10.3390/nu16081189. [PMID: 38674879]
  • Misaki Kojima, Masakuni Degawa. Causes of Sex Differences in Serum Cholesterol and Triglyceride Levels in Meishan Pigs. Biological & pharmaceutical bulletin. 2024; 47(3):606-610. doi: 10.1248/bpb.b23-00895. [PMID: 38462492]
  • Y Y Han, Q H Zhang, W S Chen, Z L Li, D Xie, S L Zhang, H Lu, L W Wang, Z H Xu, L Z Zhang. Fermented rape pollen powder can alleviate benign prostatic hyperplasia in rats by reducing hormone content and changing gut microbiota. Beneficial microbes. 2023 Nov; 14(5):503-524. doi: 10.1163/18762891-20230039. [PMID: 38656098]
  • Guo-Yu Gong, Sheng-Yan Xi, Cheng-Chen Li, Wen-Li Tang, Xue-Ming Fu, Yuan-Peng Huang. Bushen Tongluo formula ameliorated testosterone propionate-induced benign prostatic hyperplasia in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Aug; 120(?):155048. doi: 10.1016/j.phymed.2023.155048. [PMID: 37651753]
  • Shanshan Wang, Wenjiang He, Wenzhi Li, Jin-Rong Zhou, Zhiyun Du. Combination of Lycopene and Curcumin Synergistically Alleviates Testosterone-Propionate-Induced Benign Prostatic Hyperplasia in Sprague Dawley Rats via Modulating Inflammation and Proliferation. Molecules (Basel, Switzerland). 2023 Jun; 28(13):. doi: 10.3390/molecules28134900. [PMID: 37446563]
  • Deusdedit Tusubira, Patrick M Aja, Jonasi Munezero, Frank Ssedyabane, Nathim Namale, Josiah E Ifie, Peter C Agu, Clement O Ajayi, Joash Okoboi. Safety profile of colocasia esculenta tuber extracts in benign prostate hyperplasia. BMC complementary medicine and therapies. 2023 Jun; 23(1):187. doi: 10.1186/s12906-023-04018-4. [PMID: 37286957]
  • Jie Kang, Jixing Yan, Wensheng Yan. Testosterone ameliorated the behavioural deficits of gonadectomised rats and counteracted free radicals in a dosage-dependent manner. Behavioural brain research. 2023 May; 450(?):114501. doi: 10.1016/j.bbr.2023.114501. [PMID: 37207980]
  • Akansha Bisht, Ritika Gururani, Smita Jain, Rahul Shukla, Jaya Dwivedi, Swapnil Sharma. Cedrus deodara (Roxb. ex D.Don) G.Don bark fraction ameliorates metabolic, endocrine and ovarian dynamics in rats experiencing polycystic ovarian syndrome. Journal of ethnopharmacology. 2023 Apr; 306(?):116206. doi: 10.1016/j.jep.2023.116206. [PMID: 36690306]
  • Ebenezer O Farombi, Babajide O Ajayi, Edward K Opata, Abisoye O Fafioye, Adetomilola T Akinade. Kolaviron modulates angiogenesis, apoptosis and inflammatory signaling in rat model of testosterone propionate-induced benign prostate hyperplasia. Inflammopharmacology. 2023 Mar; ?(?):. doi: 10.1007/s10787-023-01171-7. [PMID: 36881348]
  • Myunghee Kim, Phuong Tran, Jun Yin, Jungbin Song, Hocheol Kim. Cinnamomum cassia and Rosa laevigata Mixture Improves Benign Prostatic Hyperplasia in Rats by Regulating Androgen Receptor Signaling and Apoptosis. Nutrients. 2023 Feb; 15(4):. doi: 10.3390/nu15040818. [PMID: 36839177]
  • Young-Jin Choi, Meiqi Fan, Nishala Erandi Wedamulla, Yujiao Tang, Sung Mun Bae, Ji-Young Hwang, Eun-Kyung Kim. Inhibitory effects of Centella asiatica (L.) Urban on enlarged prostate through androgen receptor and PI3K/Akt signaling pathways. Food & function. 2022 Oct; 13(19):10235-10247. doi: 10.1039/d2fo00841f. [PMID: 36124918]
  • Ja Yeon Park, Woo Yong Park, Jinbong Park, Kwang Seok Ahn, Jun Hee Lee, Hyun Jeong Kwak, Jae-Young Um. Therapeutic role of Glycyrrhiza Uralensis fisher on benign prostatic hyperplasia through 5 alpha reductase regulation and apoptosis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Oct; 105(?):154371. doi: 10.1016/j.phymed.2022.154371. [PMID: 35964456]
  • Jessica Venugopal, Jintao Wang, Chiao Guo, Daniel T Eitzman. Amiodarone improves anemia in a murine model of sickle cell disease and is associated with increased erythrocyte bis(monoacylglycerol) phosphate. Scientific reports. 2022 09; 12(1):16437. doi: 10.1038/s41598-022-20955-5. [PMID: 36180774]
  • Kate Eleazu, Patrick Maduabuchi Aja, Chinedum Ogbonnaya Eleazu. Cocoyam (Colocasia esculenta) modulates some parameters of testosterone propionate-induced rat model of benign prostatic hyperplasia. Drug and chemical toxicology. 2022 Sep; 45(5):1923-1933. doi: 10.1080/01480545.2021.1892956. [PMID: 33641553]
  • Woo Yong Park, Gahee Song, Ja Yeon Park, Kwang Seok Ahn, Hyun Jeong Kwak, Jinbong Park, Jun Hee Lee, Jae-Young Um. Ellagic acid improves benign prostate hyperplasia by regulating androgen signaling and STAT3. Cell death & disease. 2022 06; 13(6):554. doi: 10.1038/s41419-022-04995-3. [PMID: 35715415]
  • Hyo-Jung Kim, Byung-Hak Kim, Bo-Ram Jin, Sang Jae Park, Hyo-Jin An. Purple Corn Extract Improves Benign Prostatic Hyperplasia by Regulating Prostate Cell Proliferation and Apoptosis. Journal of agricultural and food chemistry. 2022 May; 70(18):5561-5569. doi: 10.1021/acs.jafc.1c07955. [PMID: 35466676]
  • Basma H Marghani, Alaa Fehaid, Ahmed I Ateya, Mohamed Aboul Ezz, Rasha M Saleh. Photothermal therapeutic potency of plasmonic silver nanoparticles for apoptosis and anti-angiogenesis in testosterone induced benign prostate hyperplasia in rats. Life sciences. 2022 Feb; 291(?):120240. doi: 10.1016/j.lfs.2021.120240. [PMID: 34942164]
  • Thuy Doan Minh, Tuan Nguyen Thanh Ha, Thuan Nguyen Duy, Ngan Nguyen Hoang, Dung PhamTien, Hung Pham Thai, Hoa Nguyen Thi, Phuong Dang Thi Lan, Binh Pham Quoc, D Y Ivkin, M N Povydysh, Bang Nguyen Cong, M V Krasnova. Linh Phu Khang Tue Tinh inhibited prostate proliferation in rats induced benign prostatic hyperplasia by testosterone propionate. Journal of ethnopharmacology. 2021 Oct; 279(?):114388. doi: 10.1016/j.jep.2021.114388. [PMID: 34224813]
  • Linghe Zang, Yuwei Zhang, Jing Zhao, Yunxia Yuan, Yi Wen, Jiaxin Lian, Shuailong Chen, Yiran Chen, Weiyi Liu, Ze Niu, Xinyue Wang, Chunlin Peng, Wenxin Zhang, Zhaoqing Meng, Jincai Lu. A metabolomics study of Qianliexin capsule treatment of benign prostatic hyperplasia induced by testosterone propionate in the rat model. Analytical biochemistry. 2021 09; 628(?):114258. doi: 10.1016/j.ab.2021.114258. [PMID: 34081927]
  • Hyo-Jung Kim, Bo-Ram Jin, Hyo-Jin An. Psoralea corylifolia L. extract ameliorates benign prostatic hyperplasia by regulating prostate cell proliferation and apoptosis. Journal of ethnopharmacology. 2021 Jun; 273(?):113844. doi: 10.1016/j.jep.2021.113844. [PMID: 33485982]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Marta Jerez-Peña, Borja Salvador-Culla, María F de la Paz, Rafael I Barraquer. Bilateral Boston keratoprosthesis type 1 in a case of severe Mooren's ulcer. European journal of ophthalmology. 2021 Mar; 31(2):NP33-NP38. doi: 10.1177/1120672120909768. [PMID: 32141311]
  • Fangfang Wang, Ningning Xie, Yan Wu, Qing Zhang, Yuhang Zhu, Minchen Dai, Jue Zhou, Jiexue Pan, Mengling Tang, Qi Cheng, Biwei Shi, Qinyuan Guo, Xinling Li, Lifeng Xie, Bing Wang, Dongxia Yang, Qing Weng, Lanzhong Guo, Jisheng Ye, Mingwo Pan, Shuyi Zhang, Hua Zhou, Cailan Zhen, Ping Liu, Ke Ning, Lisa Brackenridge, Paul J Hardiman, Fan Qu. Association between circadian rhythm disruption and polycystic ovary syndrome. Fertility and sterility. 2021 03; 115(3):771-781. doi: 10.1016/j.fertnstert.2020.08.1425. [PMID: 33358334]
  • Misaki Kojima, Masakuni Degawa. Androgen-Dependent Differences in the Amounts of CYP mRNAs in the Pig Kidney. Biological & pharmaceutical bulletin. 2021; 44(8):1120-1128. doi: 10.1248/bpb.b21-00333. [PMID: 34334497]
  • Patience N Ogbu, Lawrence U S Ezeanyika, Victor N Eji Ogugua, Ikechukwu M Ogbu, Chinyere Aloke, Gertrude N Ony. Sphenostylis stenocarpa Seed Extract Attenuates Dyslipidemia in Testosterone Propionate-induced Benign Prostatic Hyperplasia in Rats. Pakistan journal of biological sciences : PJBS. 2021 Jan; 24(1):151-157. doi: 10.3923/pjbs.2021.151.157. [PMID: 33683042]
  • Asmaa Mohamed Abdel-Aziz, Nashwa Fathy Gamal El-Tahawy, Medhat Atta Salah Abdel Haleem, Mostafa Mouard Mohammed, Ahmed Issam Ali, Yasmine F Ibrahim. Amelioration of testosterone-induced benign prostatic hyperplasia using febuxostat in rats: The role of VEGF/TGFβ and iNOS/COX-2. European journal of pharmacology. 2020 Dec; 889(?):173631. doi: 10.1016/j.ejphar.2020.173631. [PMID: 33031799]
  • Patience N Ogbu, Evelyn O Ugota, Rita U Onwuka, Ikechukwu M Ogbu, Chinyere Aloke. Effect of acetogenin fraction of Annona muricata leaves on antioxidant status and some indices of benign prostatic hyperplasia in rats. Redox report : communications in free radical research. 2020 Dec; 25(1):80-86. doi: 10.1080/13510002.2020.1804711. [PMID: 32878595]
  • Margaret A Zimmerman, Benard O Ogola, Mary M Wilkinson, Bruna Visniauskas, Carmen De Miguel, Jill M Daniel, Sarah H Lindsey. Medroxyprogesterone opposes estradiol-induced renal damage in midlife ovariectomized Long Evans rats. Menopause (New York, N.Y.). 2020 12; 27(12):1411-1419. doi: 10.1097/gme.0000000000001675. [PMID: 33109993]
  • Diego G Rocha, Mary Ane G Lana, Débora C S de Assis, Rodinei Augusti, Adriana F Faria. Determination of Steroids in Bovine Serum: Validation of a Reliable LC-MS/MS Method and In Vivo Studies with Boldenone Undecylenate and Testosterone Propionate. Journal of agricultural and food chemistry. 2020 Oct; 68(41):11545-11552. doi: 10.1021/acs.jafc.0c03621. [PMID: 32960588]
  • Eman M Elbaz, Hebat Allah A Amin, Ahmed S Kamel, Sherehan M Ibrahim, Hebatullah S Helmy. Immunomodulatory effect of diallyl sulfide on experimentally-induced benign prostate hyperplasia via the suppression of CD4+T/IL-17 and TGF-β1/ERK pathways. Inflammopharmacology. 2020 Oct; 28(5):1407-1420. doi: 10.1007/s10787-020-00743-1. [PMID: 32785828]
  • Diego G Rocha, Mary Ane G Lana, Débora C S de Assis, Silvana V Cançado, Rodinei Augusti, Adriana F Faria. Determination of steroids in bovine hair: Validation of a microwave-assisted chemical derivatization method using liquid chromatography-tandem mass spectrometry and in vivo studies. Drug testing and analysis. 2020 Aug; 12(8):1078-1086. doi: 10.1002/dta.2815. [PMID: 32384229]
  • Jinhyung Rho, Chang-Seob Seo, Hee-Seon Park, Hye-Yun Jeong, Og-Sung Moon, Young-Won Seo, Hwa-Young Son, Young-Suk Won, Hyo-Jung Kwun. Asteris Radix et Rhizoma suppresses testosterone-induced benign prostatic hyperplasia in rats by regulating apoptosis and inflammation. Journal of ethnopharmacology. 2020 Jun; 255(?):112779. doi: 10.1016/j.jep.2020.112779. [PMID: 32209388]
  • Xi Jin, Tianhai Lin, Guang Yang, Huawei Cai, Bo Tang, Xinyang Liao, Huifang Li, Xiaoting Chen, Lina Gong, Hang Xu, Yi Sun, Ping Tan, Jianqiong Yin, Hongwen Ma, Jianzhong Ai, Kunjie Wang, Qiang Wei, Lu Yang, Hong Li. Use of Tregs as a cell-based therapy via CD39 for benign prostate hyperplasia with inflammation. Journal of cellular and molecular medicine. 2020 05; 24(9):5082-5096. doi: 10.1111/jcmm.15137. [PMID: 32191396]
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