oleandomycin (BioDeep_00000407804)

 

Secondary id: BioDeep_00000002609

natural product


代谢物信息卡片


(3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-hydroxy-5,7,8,11,13,15-hexamethyl-4,10-dioxo-14-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1,9-dioxaspiro[2.13]hexadec-12-yl 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranoside

化学式: C35H61NO12 (687.4194)
中文名称: 奥林霉素
谱图信息: 最多检出来源 Viridiplantae(lipidsearch) 18.93%

分子结构信息

SMILES: CC1CC(C(C(O1)OC2C(CC3(CO3)C(=O)C(C(C(C(OC(=O)C(C(C2C)OC4CC(C(C(O4)C)O)OC)C)C)C)O)C)C)O)N(C)C
InChI: InChI=1S/C35H61NO12/c1-16-14-35(15-43-35)32(40)19(4)27(37)18(3)22(7)46-33(41)21(6)31(47-26-13-25(42-11)28(38)23(8)45-26)20(5)30(16)48-34-29(39)24(36(9)10)12-17(2)44-34/h16-31,34,37-39H,12-15H2,1-11H3/t16-,17+,18-,19+,20+,21+,22+,23-,24-,25-,26-,27-,28-,29+,30-,31-,34-,35+/m0/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01F - Macrolides, lincosamides and streptogramins > J01FA - Macrolides
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic

同义名列表

3 个代谢物同义名

oleandomycin; (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-hydroxy-5,7,8,11,13,15-hexamethyl-4,10-dioxo-14-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1,9-dioxaspiro[2.13]hexadec-12-yl 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranoside; Oleandomycin



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

61 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 DMD, G6PD, GLUL, MSRA, POMC, SPTBN4
Golgi apparatus, trans-Golgi network membrane 1 FURIN
Peripheral membrane protein 2 DMD, G6PD
Endosome membrane 1 FURIN
Nucleus 5 DMD, GLUL, MPO, NR1I2, OMP
cytosol 7 DMD, G6PD, GLUL, GPT, MSRA, OMP, SPTBN4
nuclear body 1 NR1I2
trans-Golgi network 1 FURIN
nucleoplasm 5 ATP2B1, MPO, MSRA, NR1I2, TMPRSS2
Cell membrane 4 ATP2B1, FURIN, GLUL, TMPRSS2
Lipid-anchor 2 GLUL, MSRA
Cytoplasmic side 1 DMD
Multi-pass membrane protein 1 ATP2B1
Synapse 3 ATP2B1, DMD, OMP
cell junction 1 SPTBN4
cell surface 2 DMD, FURIN
glutamatergic synapse 1 ATP2B1
Golgi apparatus 1 FURIN
Golgi membrane 1 FURIN
neuronal cell body 2 OMP, SPTBN4
presynaptic membrane 1 ATP2B1
sarcolemma 1 DMD
Cytoplasm, cytosol 2 G6PD, GLUL
Lysosome 1 MPO
plasma membrane 8 ATP2B1, DMD, FURIN, GLUL, IGHE, MSRA, SPTBN4, TMPRSS2
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ATP2B1, DMD, FURIN, G6PD, MSRA, SPTBN4, TMPRSS2
axon 1 OMP
basolateral plasma membrane 1 ATP2B1
extracellular exosome 11 ATP2B1, FURIN, G6PD, GLUL, GPT, LYZ, MPO, MSRA, SPINK1, SPTBN4, TMPRSS2
endoplasmic reticulum 2 FURIN, GLUL
extracellular space 5 GH1, IGHE, LYZ, MPO, POMC
intercalated disc 1 SPTBN4
mitochondrion 2 GLUL, MSRA
protein-containing complex 1 DMD
intracellular membrane-bounded organelle 4 ATP2B1, G6PD, MPO, MSRA
filopodium 1 DMD
Single-pass type I membrane protein 2 FURIN, IGHE
Secreted 6 ADAMTS1, FURIN, GH1, POMC, PRB1, SPINK1
extracellular region 10 ADAMTS1, FURIN, GH1, IGHE, LYZ, MLN, MPO, POMC, PRB1, TMPRSS2
cytoplasmic side of plasma membrane 1 G6PD
Single-pass membrane protein 1 MLN
transcription regulator complex 1 NR1I2
centriolar satellite 1 G6PD
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Secreted, extracellular space, extracellular matrix 1 ADAMTS1
actin cytoskeleton 1 MSRA
Z disc 1 DMD
cytoplasmic vesicle 1 ADAMTS1
midbody 1 MSRA
Single-pass type II membrane protein 1 TMPRSS2
postsynaptic membrane 1 DMD
Cell membrane, sarcolemma 1 DMD
Membrane raft 2 DMD, FURIN
Cytoplasm, cytoskeleton 2 DMD, SPTBN4
extracellular matrix 1 ADAMTS1
basement membrane 1 ADAMTS1
PML body 1 SPTBN4
secretory granule 2 MPO, POMC
lateral plasma membrane 1 ATP2B1
Nucleus outer membrane 1 DMD
nuclear outer membrane 1 DMD
Postsynaptic cell membrane 1 DMD
chromatin 1 NR1I2
IgE immunoglobulin complex 1 IGHE
cell projection 2 ATP2B1, SPTBN4
cytoskeleton 1 DMD
Cytoplasm, cell cortex 1 SPTBN4
actin filament 1 SPTBN4
Basolateral cell membrane 1 ATP2B1
[Isoform 2]: Cell membrane 1 IGHE
endosome lumen 1 GH1
cell body fiber 1 SPTBN4
axon initial segment 1 SPTBN4
Presynaptic cell membrane 1 ATP2B1
cell body 1 GLUL
intermediate filament cytoskeleton 1 NR1I2
filopodium membrane 1 DMD
azurophil granule 1 MPO
trans-Golgi network transport vesicle 1 FURIN
Microsome 1 GLUL
secretory granule lumen 1 POMC
Golgi lumen 1 FURIN
nuclear matrix 1 SPTBN4
cortical actin cytoskeleton 1 SPTBN4
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
node of Ranvier 1 SPTBN4
paranode region of axon 1 SPTBN4
azurophil granule lumen 2 LYZ, MPO
Sarcoplasmic reticulum membrane 1 MLN
immunological synapse 1 ATP2B1
Single-pass type IV membrane protein 1 DMD
phagocytic vesicle lumen 1 MPO
axon hillock 1 SPTBN4
spectrin 1 SPTBN4
costamere 1 DMD
[Transmembrane protease serine 2 catalytic chain]: Secreted 1 TMPRSS2
dystrophin-associated glycoprotein complex 1 DMD
cell-substrate junction 1 DMD
[Isoform 3]: Cell membrane 1 IGHE
glial cell projection 1 GLUL
growth hormone receptor complex 1 GH1
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
neuron projection terminus 1 DMD
photoreceptor ribbon synapse 1 ATP2B1
syntrophin complex 1 DMD
juxtaparanode region of axon 1 SPTBN4
organelle 2 DMD, SPTBN4
plasma membrane bounded cell projection 1 DMD


文献列表

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