picolinic acid (BioDeep_00000405522)

Main id: BioDeep_00000001406

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


2-Pyridinecarboxylic acid

化学式: C6H5NO2 (123.032)
中文名称: 2-吡啶甲酸, 吡啶甲酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=NC(=C1)C(=O)O
InChI: InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)

描述信息

A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents
Picolinic acid (PCL 016) is a topical antiviral agent, which inhibits adenovirus replication in rabbits.

同义名列表

6 个代谢物同义名

2-Pyridinecarboxylic acid; 2-Picolinic acid; picolinic acid; PCL 016; Picolinic acid; Picolinic acid



数据库引用编号

32 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

42 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ACMSD, ALB, CHAT, CYP1A1, DBH, IDO1, MTOR, NOS2, PPARG
Peripheral membrane protein 2 CYP1A1, MTOR
Endosome membrane 1 TF
Endoplasmic reticulum membrane 2 CYP1A1, MTOR
Nucleus 5 ALB, CHAT, MTOR, NOS2, PPARG
cytosol 10 ACMSD, ALB, CHAT, IDO1, KMO, MTOR, NOS2, NRK, PPARG, TDO2
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 1 ALB
nucleoplasm 3 MTOR, NOS2, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 1 TNF
Cytoplasmic side 1 MTOR
Multi-pass membrane protein 1 KMO
Golgi apparatus membrane 1 MTOR
Synapse 2 CHAT, DBH
cell surface 2 TF, TNF
Golgi apparatus 1 ALB
Golgi membrane 1 MTOR
lysosomal membrane 1 MTOR
mitochondrial inner membrane 1 CYP1A1
neuronal cell body 1 TNF
Cytoplasm, cytosol 2 IDO1, NOS2
Lysosome 1 MTOR
plasma membrane 4 IFNLR1, NOS2, TF, TNF
Membrane 6 ACMSD, DBH, IFNLR1, KMO, MTOR, NRK
apical plasma membrane 1 TF
extracellular exosome 2 ALB, TF
Lysosome membrane 1 MTOR
endoplasmic reticulum 2 ALB, DBH
extracellular space 10 ALB, CRP, DBH, IL10, IL2, IL4, IL6, KMO, TF, TNF
perinuclear region of cytoplasm 3 NOS2, PPARG, TF
mitochondrion 2 CYP1A1, KMO
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 3 CYP1A1, DBH, PPARG
Microsome membrane 2 CYP1A1, MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 IFNLR1
Secreted 8 ALB, CRP, DBH, IL10, IL2, IL4, IL6, TF
extracellular region 9 ALB, CRP, DBH, IL10, IL2, IL4, IL6, TF, TNF
Mitochondrion outer membrane 2 KMO, MTOR
mitochondrial outer membrane 2 KMO, MTOR
basal part of cell 1 TF
anchoring junction 1 ALB
centriolar satellite 1 DBH
external side of plasma membrane 1 TNF
cytoplasmic vesicle 1 TF
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 1 TF
clathrin-coated pit 1 TF
recycling endosome 2 TF, TNF
Single-pass type II membrane protein 2 DBH, TNF
vesicle 1 TF
Cytoplasm, perinuclear region 1 NOS2
Mitochondrion inner membrane 1 CYP1A1
Membrane raft 1 TNF
Peroxisome 1 NOS2
peroxisomal matrix 1 NOS2
Nucleus, PML body 1 MTOR
PML body 1 MTOR
Late endosome 1 TF
receptor complex 1 PPARG
neuron projection 1 CHAT
ciliary basal body 1 ALB
chromatin 1 PPARG
stereocilium bundle 1 IDO1
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, TF
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
basal plasma membrane 1 TF
secretory granule lumen 2 DBH, TF
HFE-transferrin receptor complex 1 TF
secretory granule membrane 1 DBH
endoplasmic reticulum lumen 3 ALB, IL6, TF
platelet alpha granule lumen 1 ALB
endocytic vesicle 1 TF
clathrin-coated endocytic vesicle membrane 1 TF
Cytoplasmic vesicle, secretory vesicle membrane 1 DBH
Cytoplasmic vesicle, phagosome 1 MTOR
vesicle coat 1 TF
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
transport vesicle membrane 1 DBH
cortical cytoskeleton 1 NOS2
interleukin-6 receptor complex 1 IL6
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
smooth muscle contractile fiber 1 IDO1
ciliary transition fiber 1 ALB
dense body 1 TF
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Yu Li, Lu Wei, Pengfei Zhang, Juan Xiao, Zhiqiang Guo, Qiongyao Fu. Bioaccumulation of dietary CrPic, Cr(III) and Cr(VI) in juvenile coral trout (Plectropomus leopardus). Ecotoxicology and environmental safety. 2022 Jul; 240(?):113692. doi: 10.1016/j.ecoenv.2022.113692. [PMID: 35636236]
  • Vivekananda Mandal, Narendra Nath Ghosh, Prashanta Kumar Mitra, Sukhendu Mandal, Vivekananda Mandal. Production and characterization of a broad-spectrum antimicrobial 5-butyl-2-pyridine carboxylic acid from Aspergillus fumigatus nHF-01. Scientific reports. 2022 04; 12(1):6006. doi: 10.1038/s41598-022-09925-z. [PMID: 35397665]
  • Murat Cihan, Özlem Doğan, Ceyhan Ceran Serdar, Arzu Altunçekiç Yıldırım, Celali Kurt, Muhittin A Serdar. Kynurenine pathway in Coronavirus disease (COVID-19): Potential role in prognosis. Journal of clinical laboratory analysis. 2022 Mar; 36(3):e24257. doi: 10.1002/jcla.24257. [PMID: 35092710]
  • Hassan Mozaffari-Khosravi, Sara Jambarsan, Fazad Karimpour, Seyyed Ebrahim Hosseini, Behrooz Ebrahimzadeh Kour. Study Protocol for a Randomized Controlled Trial Evaluating the Effectof Chromium Picolinate Supplementation on Gene Expression of TumorNecrosis Factor-α and DNA Damage in Metabolic Syndrome Patients. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. 2021 Nov; 32(6):1671-1678. doi: 10.4103/1319-2442.352428. [PMID: 35946280]
  • Fateme Kooshki, Fardin Moradi, Arash Karimi, Hamid Reza Niazkar, Manouchehr Khoshbaten, Vahid Maleki, Bahram Pourghassem Gargari. Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial. European journal of gastroenterology & hepatology. 2021 10; 33(10):1298-1306. doi: 10.1097/meg.0000000000001830. [PMID: 32804855]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Katarzyna Ognik, Wojciech Dworzański, Iwona Sembratowicz, Bartosz Fotschki, Ewelina Cholewińska, Piotr Listos, Jerzy Juśkiewicz. The effect of the high-fat diet supplemented with various forms of chromium on rats body composition, liver metabolism and organ histology Cr in liver metabolism and histology of selected organs. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2021 Mar; 64(?):126705. doi: 10.1016/j.jtemb.2020.126705. [PMID: 33383354]
  • Alexandra N Kovács, Norbert Varga, Ádám Juhász, Edit Csapó. Serum protein-hyaluronic acid complex nanocarriers: Structural characterisation and encapsulation possibilities. Carbohydrate polymers. 2021 Jan; 251(?):117047. doi: 10.1016/j.carbpol.2020.117047. [PMID: 33142605]
  • Fardin Moradi, Fateme Kooshki, Forough Nokhostin, Manouchehr Khoshbaten, Hadi Bazyar, Bahram Pourghassem Gargari. A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2021 Jan; 63(?):126659. doi: 10.1016/j.jtemb.2020.126659. [PMID: 33045675]
  • Yang Hai, Mengbin Chen, Arthur Huang, Yi Tang. Biosynthesis of Mycotoxin Fusaric Acid and Application of a PLP-Dependent Enzyme for Chemoenzymatic Synthesis of Substituted l-Pipecolic Acids. Journal of the American Chemical Society. 2020 11; 142(46):19668-19677. doi: 10.1021/jacs.0c09352. [PMID: 33155797]
  • Ferenc Tömösi, Gábor Kecskeméti, Edina Katalin Cseh, Elza Szabó, Cecília Rajda, Róbert Kormány, Zoltán Szabó, László Vécsei, Tamás Janáky. A validated UHPLC-MS method for tryptophan metabolites: Application in the diagnosis of multiple sclerosis. Journal of pharmaceutical and biomedical analysis. 2020 Jun; 185(?):113246. doi: 10.1016/j.jpba.2020.113246. [PMID: 32182446]
  • Thomas I Kostelnik, Xiaozhu Wang, Lily Southcott, Hannah K Wagner, Manja Kubeil, Holger Stephan, María de Guadalupe Jaraquemada-Peláez, Chris Orvig. Rapid Thermodynamically Stable Complex Formation of [nat/111In]In3+, [nat/90Y]Y3+, and [nat/177Lu]Lu3+ with H6dappa. Inorganic chemistry. 2020 May; 59(10):7238-7251. doi: 10.1021/acs.inorgchem.0c00671. [PMID: 32337985]
  • Kehong Ding, Meghan E McGee-Lawrence, Helen Kaiser, Anuj K Sharma, Jessica L Pierce, Debra L Irsik, Wendy B Bollag, Jianrui Xu, Qing Zhong, William Hill, Xing-Ming Shi, Sadanand Fulzele, Eileen J Kennedy, Mohammed Elsalanty, Mark W Hamrick, Carlos M Isales. Picolinic acid, a tryptophan oxidation product, does not impact bone mineral density but increases marrow adiposity. Experimental gerontology. 2020 05; 133(?):110885. doi: 10.1016/j.exger.2020.110885. [PMID: 32088397]
  • Praveen K Kathare, Sunethra Dharmasiri, Eric D Vincill, Pratyush Routray, Idrees Ahmad, Daniel M Roberts, Nihal Dharmasiri. Arabidopsis PIC30 encodes a major facilitator superfamily transporter responsible for the uptake of picolinate herbicides. The Plant journal : for cell and molecular biology. 2020 04; 102(1):18-33. doi: 10.1111/tpj.14608. [PMID: 31710151]
  • Shan Shan Qi, Hong Xing Zheng, Hai Jiang, Li Ping Yuan, Le Chen Dong. Protective Effects of Chromium Picolinate Against Diabetic-Induced Renal Dysfunction and Renal Fibrosis in Streptozotocin-Induced Diabetic Rats. Biomolecules. 2020 03; 10(3):. doi: 10.3390/biom10030398. [PMID: 32143429]
  • Ragip Pala, Mehmet Akif Sari, Fusun Erten, Besir Er, Mehmet Tuzcu, Cemal Orhan, Patrick Brice Defo Deeh, Nurhan Sahin, Vedat Cinar, James R Komorowski, Kazim Sahin. The effects of chromium picolinate on glucose and lipid metabolism in running rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2020 Mar; 58(?):126434. doi: 10.1016/j.jtemb.2019.126434. [PMID: 31778961]
  • Romain Colle, Perrine Masson, Céline Verstuyft, Bruno Fève, Erwan Werner, Claire Boursier-Neyret, Bernard Walther, Denis J David, Bruno Boniface, Bruno Falissard, Philippe Chanson, Emmanuelle Corruble, Laurent Becquemont. Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case-control study. Psychiatry and clinical neurosciences. 2020 Feb; 74(2):112-117. doi: 10.1111/pcn.12944. [PMID: 31599111]
  • Karen M Ryan, Kelly A Allers, Declan M McLoughlin, Andrew Harkin. Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy. Brain, behavior, and immunity. 2020 01; 83(?):153-162. doi: 10.1016/j.bbi.2019.10.005. [PMID: 31606477]
  • Irene Iskandar, Yahdiana Harahap, Tri Rahayu Wijayanti, Monika Sandra, Budi Prasaja, Prawitasari Cahyaningsih. Efficacy and tolerability of a nutraceutical combination of red yeast rice, guggulipid, and chromium picolinate evaluated in a randomized, placebo-controlled, double-blind study. Complementary therapies in medicine. 2020 Jan; 48(?):102282. doi: 10.1016/j.ctim.2019.102282. [PMID: 31987238]
  • Patrick Heilman, Matthew N Hill, Mary Coussons-Read, Lena Brundin, Emil F Coccaro. Role of the kynurenine pathway and the endocannabinoid system as modulators of inflammation and personality traits. Psychoneuroendocrinology. 2019 12; 110(?):104434. doi: 10.1016/j.psyneuen.2019.104434. [PMID: 31525567]
  • Carlos Eduardo Aucique-Pérez, Renata Sousa Resende, Lara Beatriz Cruz Neto, Fernanda Dornelas, Fábio Murilo DaMatta, Fabrício Ávila Rodrigues. Picolinic acid spray stimulates the antioxidative metabolism and minimizes impairments on photosynthesis on wheat leaves infected by Pyricularia oryzae. Physiologia plantarum. 2019 Dec; 167(4):628-644. doi: 10.1111/ppl.12917. [PMID: 30628091]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • L Lu, L L Zhao, S Y Dong, X D Liao, X Y Dong, L Y Zhang, X G Luo. Dietary supplementation of organic or inorganic chromium modulates the immune responses of broilers vaccinated with Avian Influenza virus vaccine. Animal : an international journal of animal bioscience. 2019 May; 13(5):983-991. doi: 10.1017/s1751731118002379. [PMID: 30277192]
  • Nafrialdi Nafrialdi, Johannes Hudyono, Frans D Suyatna, Arini Setiawati. Safety and Efficacy of NC120 for Improving Lipid Profile: A Double Blind Randomized Controlled Trial. Acta medica Indonesiana. 2019 Jan; 51(1):19-25. doi: ". [PMID: 31073102]
  • Diana Ciubotariu, Mihai Nechifor, Gabriel Dimitriu. Chromium picolinate reduces morphine-dependence in rats, while increasing brain serotonin levels. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2018 Dec; 50(?):676-683. doi: 10.1016/j.jtemb.2018.06.025. [PMID: 30269760]
  • Shumin Zhang, Xiaoming Sun, Xiudong Liao, Lin Lu, Liyang Zhang, Qiugang Ma, Xugang Luo. Dietary Supplementation with Chromium Picolinate Influences Serum Glucose and Immune Response of Brown-Egg Laying Hens. Biological trace element research. 2018 Oct; 185(2):448-455. doi: 10.1007/s12011-017-1232-7. [PMID: 29380257]
  • Hongxia Li, Xiao Meng, Wenju Wan, Hanliang Liu, Minmin Sun, Hongwei Wang, Jiting Wang. Effects of chromium picolinate supplementation on growth, body composition, and biochemical parameters in Nile tilapia Oreochromis niloticus. Fish physiology and biochemistry. 2018 Oct; 44(5):1265-1274. doi: 10.1007/s10695-018-0514-0. [PMID: 29961187]
  • Mingchun Ren, Ahmed Mokrani, Hualiang Liang, Ke Ji, Jun Xie, Xianping Ge, Bo Liu. Dietary Chromium Picolinate Supplementation Affects Growth, Whole-Body Composition, and Gene Expression Related to Glucose Metabolism and Lipogenesis in Juvenile Blunt Snout Bream, Megalobrama amblycephala. Biological trace element research. 2018 Sep; 185(1):205-215. doi: 10.1007/s12011-018-1242-0. [PMID: 29344818]
  • Mohamed Mahmoud Elseweidy, Rawia Sarhan Amin, Hebatallah Husseini Atteia, Maha Abdo Aly. Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats. Biological trace element research. 2018 Jul; 184(1):119-126. doi: 10.1007/s12011-017-1167-z. [PMID: 28975521]
  • Lu Jiang, John B Vincent, Melissa M Bailey. [Cr3O(O2CCH2CH3)6(H2O)3]NO3·H2O (Cr3) Toxicity Potential in Bacterial and Mammalian Cells. Biological trace element research. 2018 Jun; 183(2):342-350. doi: 10.1007/s12011-017-1132-x. [PMID: 28879636]
  • Weiwei Feng, Qian Li, Wei Wang, Ting Zhao, Yun Feng, Fang Li, Guanghua Mao, Yao Chen, Yangyang Ding, Liuqing Yang, Xiangyang Wu. Pharmacokinetics and bioavailability of chromium malate and its influence on trace metals absorption after oral or intravenous administration. Indian journal of pharmacology. 2018 Mar; 50(2):75-83. doi: 10.4103/ijp.ijp_505_17. [PMID: 30100655]
  • Noha M Shafik, Amal Baalash, Abla M Ebeid. Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers. Biological trace element research. 2017 Dec; 180(2):255-264. doi: 10.1007/s12011-017-1010-6. [PMID: 28409410]
  • Zhigang Wang, Shuhan Tang, Masao Hattori, Hailong Zhang, Xiuhong Wu. Simultaneous determination of paeonilactone A and paeonilactone B in rat plasma after oral administration of albiflorin by UPLC/TOF/MS following picolinoyl derivatization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Sep; 1061-1062(?):327-333. doi: 10.1016/j.jchromb.2017.07.047. [PMID: 28783562]
  • Rituparna Ganguly, Soumyadip Sahu, Vahagn Ohanyan, Rebecca Haney, Ronaldo J Chavez, Shivani Shah, Siri Yalamanchili, Priya Raman. Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE-/- mice. Scientific reports. 2017 03; 7(?):45279. doi: 10.1038/srep45279. [PMID: 28345659]
  • Tianzhu Zang, Daniel Tamae, Clementina Mesaros, Qingqing Wang, Meng Huang, Ian A Blair, Trevor M Penning. Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry. The Journal of steroid biochemistry and molecular biology. 2017 01; 165(Pt B):342-355. doi: 10.1016/j.jsbmb.2016.08.001. [PMID: 27531846]
  • Emil F Coccaro, Royce Lee, Jennifer R Fanning, Dietmar Fuchs, Michel Goiny, Sophie Erhardt, Kyle Christensen, Lena Brundin, Mary Coussons-Read. Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects. Psychoneuroendocrinology. 2016 09; 71(?):189-96. doi: 10.1016/j.psyneuen.2016.04.024. [PMID: 27318828]
  • L Brundin, C M Sellgren, C K Lim, J Grit, E Pålsson, M Landén, M Samuelsson, K Lundgren, P Brundin, D Fuchs, T T Postolache, L Traskman-Bendz, G J Guillemin, S Erhardt. An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation. Translational psychiatry. 2016 08; 6(8):e865. doi: 10.1038/tp.2016.133. [PMID: 27483383]
  • Bruno Stéfano Lima Dallago, Bárbara Alcântara Ferreira Lima, Shélida Vasconcelos Braz, Vanessa da Silva Mustafa, Concepta McManus, Tiago do Prado Paim, Aline Campeche, Edgard Franco Gomes, Helder Louvandini. Tissue accumulation and urinary excretion of Cr in chromium picolinate (CrPic)-supplemented lambs. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2016 May; 35(?):30-5. doi: 10.1016/j.jtemb.2016.01.004. [PMID: 27049124]
  • Sherif Ashoush, Amgad Abou-Gamrah, Hassan Bayoumy, Noura Othman. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial. The journal of obstetrics and gynaecology research. 2016 Mar; 42(3):279-85. doi: 10.1111/jog.12907. [PMID: 26663540]
  • Cancai Zheng, Yanling Huang, Fang Xiao, Xi Lin, Karen Lloyd. Effects of Supplemental Chromium Source and Concentration on Growth, Carcass Characteristics, and Serum Lipid Parameters of Broilers Reared Under Normal Conditions. Biological trace element research. 2016 Feb; 169(2):352-8. doi: 10.1007/s12011-015-0419-z. [PMID: 26123165]
  • Zephy Doddigarla, Jamal Ahmad, Iqbal Parwez. Effect of chromium picolinate and melatonin either in single or in a combination in high carbohydrate diet-fed male Wistar rats. BioFactors (Oxford, England). 2016 Jan; 42(1):106-14. doi: 10.1002/biof.1253. [PMID: 26662671]
  • Eunju Cha, Kang Mi Lee, Ki Duk Park, Kyung Seok Park, Kwang-Woo Lee, Sung-Min Kim, Jaeick Lee. Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag+CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: Increased Levels and Association with Disability during Acute Attack. PloS one. 2016; 11(12):e0167819. doi: 10.1371/journal.pone.0167819. [PMID: 27942009]
  • Weiwei Feng, Weijie Zhang, Ting Zhao, Guanghua Mao, Wei Wang, Xueshan Wu, Zhaoxiang Zhou, Jing Huang, Yongtuan Bao, Liuqing Yang, Xiangyang Wu. Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague-Dawley Rats. Biological trace element research. 2015 Nov; 168(1):150-68. doi: 10.1007/s12011-015-0336-1. [PMID: 25876088]
  • Bruno Stéfano Lima Dallago, ShélidaVasconcelos Braz, Tatiana Guerrero Marçola, Concepta McManus, Denise Ferreira Caldeira, Aline Campeche, Edgard Franco Gomes, Tiago Prado Paim, Bárbara Oliveira Borges, Helder Louvandini. Blood Parameters and Toxicity of Chromium Picolinate Oral Supplementation in Lambs. Biological trace element research. 2015 Nov; 168(1):91-102. doi: 10.1007/s12011-015-0347-y. [PMID: 25926085]
  • Ana N Paiva, Josivan G de Lima, Anna C Q de Medeiros, Heverton A O Figueiredo, Raiana L de Andrade, Marcela A G Ururahy, Adriana A Rezende, José Brandão-Neto, Maria das G Almeida. Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2015 Oct; 32(?):66-72. doi: 10.1016/j.jtemb.2015.05.006. [PMID: 26302914]
  • A A Seif. Chromium picolinate inhibits cholesterol-induced stimulation of platelet aggregation in hypercholesterolemic rats. Irish journal of medical science. 2015 Jun; 184(2):291-6. doi: 10.1007/s11845-014-1102-7. [PMID: 24633441]
  • YiQuan Chen, JinFa Chen, Zhiming Xi, Guidi Yang, Zujian Wu, JianRong Li, FengFu Fu. Simultaneous analysis of Cr(III), Cr(VI), and chromium picolinate in foods using capillary electrophoresis-inductively coupled plasma mass spectrometry. Electrophoresis. 2015 May; 36(9-10):1208-15. doi: 10.1002/elps.201500015. [PMID: 25752822]
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