3-Hydroxyanthranilic acid (BioDeep_00000405445)

Main id: BioDeep_00000001233

 

PANOMIX_OTCML-2023 natural product BioNovoGene_Lab2019


代谢物信息卡片


3-Hydroxyanthranilic acid

化学式: C7H7NO3 (153.0426)
中文名称: 3-羟基-2-氨基苯甲酸, 3-羟基邻氨基苯甲酸
谱图信息: 最多检出来源 Homo sapiens(blood) 57.06%

分子结构信息

SMILES: C1=CC(=C(C(=C1)O)N)C(=O)O
InChI: InChI=1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)

描述信息

An aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.
D000975 - Antioxidants > D016166 - Free Radical Scavengers
D020011 - Protective Agents > D000975 - Antioxidants
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; WJXSWCUQABXPFS-UHFFFAOYSA-N_STSL_0003_3-hydroxyanthranillic acid_8000fmol_180416_S2_LC02_MS02_37; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.

同义名列表

3 个代谢物同义名

3-Hydroxyanthranilic acid; 3-Hydroxyanthranilate; 3-Hydroxyanthranilic acid



数据库引用编号

52 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(2)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AHR, CAT, GFAP, HAAO, HTT, IDO1, KYNU, QPRT, TYR, XDH
Endosome membrane 1 HTT
Endoplasmic reticulum membrane 2 CD4, HMOX1
Nucleus 3 AHR, HMOX1, HTT
autophagosome 1 HTT
cytosol 12 AHR, CAT, GFAP, HAAO, HMOX1, HTT, IDO1, KMO, KYNU, QPRT, TDO2, XDH
dendrite 1 HTT
nucleoplasm 4 AHR, HMOX1, HTT, KYNU
Cell membrane 3 CD4, HTT, TNF
Cytoplasmic side 1 HMOX1
Multi-pass membrane protein 2 HTT, KMO
Synapse 1 HTT
cell surface 1 TNF
Golgi apparatus 1 HTT
Golgi membrane 1 INS
neuronal cell body 1 TNF
presynaptic membrane 1 HTT
Cytoplasm, cytosol 3 HAAO, IDO1, KYNU
Lysosome 1 TYR
plasma membrane 4 CD4, HTT, IFNLR1, TNF
Membrane 4 CAT, HMOX1, IFNLR1, KMO
axon 1 HTT
extracellular exosome 2 CAT, QPRT
endoplasmic reticulum 2 HMOX1, HTT
extracellular space 8 CRP, HMOX1, IL2, IL6, INS, KMO, TNF, XDH
perinuclear region of cytoplasm 3 HMOX1, HTT, TYR
mitochondrion 3 CAT, KMO, KYNU
protein-containing complex 3 AHR, CAT, HTT
intracellular membrane-bounded organelle 2 CAT, TYR
Single-pass type I membrane protein 3 CD4, IFNLR1, TYR
Secreted 4 CRP, IL2, IL6, INS
extracellular region 6 CAT, CRP, IL2, IL6, INS, TNF
Mitochondrion outer membrane 1 KMO
mitochondrial outer membrane 2 HMOX1, KMO
astrocyte end-foot 1 GFAP
mitochondrial matrix 1 CAT
transcription regulator complex 1 AHR
external side of plasma membrane 2 CD4, TNF
Melanosome membrane 1 TYR
Early endosome 2 CD4, HTT
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 HTT
Membrane raft 3 CD4, HTT, TNF
Cell junction, focal adhesion 1 HTT
focal adhesion 2 CAT, HTT
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
intermediate filament 1 GFAP
Late endosome 1 HTT
Cell projection, neuron projection 1 HTT
neuron projection 1 HTT
chromatin 1 AHR
stereocilium bundle 1 IDO1
cell projection 1 GFAP
phagocytic cup 1 TNF
centriole 1 HTT
Endomembrane system 1 HTT
endosome lumen 1 INS
aryl hydrocarbon receptor complex 1 AHR
Cytoplasmic vesicle membrane 1 HTT
Melanosome 1 TYR
cell body 1 GFAP
intermediate filament cytoskeleton 1 GFAP
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 CD4, IL6, INS
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
clathrin-coated endocytic vesicle membrane 1 CD4
postsynaptic cytosol 1 HTT
presynaptic cytosol 1 HTT
cytoplasmic side of lysosomal membrane 1 GFAP
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
catalase complex 1 CAT
inclusion body 1 HTT
catalytic complex 1 QPRT
interleukin-6 receptor complex 1 IL6
smooth muscle contractile fiber 1 IDO1
nuclear aryl hydrocarbon receptor complex 1 AHR
serotonergic synapse 1 HTT
cytosolic aryl hydrocarbon receptor complex 1 AHR
[Huntingtin]: Cytoplasm 1 HTT
[Huntingtin, myristoylated N-terminal fragment]: Cytoplasmic vesicle, autophagosome 1 HTT
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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