Lutein (BioDeep_00000402745)

natural product PANOMIX_OTCML-2023

代谢物信息卡片

(1R,4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-2-en-1-ol

化学式: C40H56O2 (568.428)
中文名称: 叶黃素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C[C@H](CC1(C)C)O)/C=C/C=C(\C)/C=C/[C@H]1C(=C[C@@H](CC1(C)C)O)C
InChI: InChI=1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+

描述信息

D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
Window width for selecting the precursor ion was 3 Da.; This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health[1]. Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti-apoptosis, through effects on reactive oxygen species (ROS)[2][3]. Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active[4].
Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health[1]. Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti-apoptosis, through effects on reactive oxygen species (ROS)[2][3]. Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active[4].

同义名列表

19 个代谢物同义名

(1R,4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-2-en-1-ol; (1R,4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-2-en-1-ol; (1R,4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-1-cyclohex-2-enol; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-2-en-1-ol; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-1-cyclohex-2-enol; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-2-en-1-ol; (3R,3R,6R)-beta,epsilon-carotene-3,3-diol; BCBcMAP01_000190; LMPR01070274; XANTHOPHYLL; CHEBI:28838; SMP1_000317; 127-40-2; NSC59193; C08601; Lutein; 4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-(4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-3,5,5-trimethylcyclohex-2-en-1-ol; (all-E)-Lutein; Lutein

数据库引用编号

24 个数据库交叉引用编号

ChEBI: CHEBI:28838
KEGG: C08601
PubChem: 5281243
PubChem: 5368396
DrugBank: DB00137
ChEMBL: CHEMBL173929
ChEMBL: CHEMBL1979448
MeSH: Lutein
CAS: 180580-60-3
CAS: 127-40-2
CAS: 38327-39-8
MoNA: MSJ00112
MoNA: MSJ00111
MoNA: PM015402
MoNA: PM008415
MoNA: PM015421
PubChem: 10794
LipidMAPS: LMPR01070030
KNApSAcK: C00003776
3DMET: B02256
NIKKAJI: J5.394E
RefMet: Lutein
medchemexpress: HY-N6947
KNApSAcK: 28838

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

189 个相关的物种来源信息

85783 - Acanthella acuta: 10.1016/0305-0491(84)90180-9
66201 - Acer palmatum: 10.1271/BBB1961.49.1211
13818 - Adiantum capillus-veneris: 10.1016/0305-1978(85)90030-4
43364 - Aesculus hippocastanum: 10.1002/(SICI)1522-2675(19981007)81:10<1815::AID-HLCA1815>3.0.CO;2-R
39269 - Agastache foeniculum: 10.1080/10412905.1992.9698114
2653732 - Ageratum corymbosum: 10.1016/0031-9422(92)83647-H
4679 - Allium cepa: 10.1021/JF00023A019
89479 - Amentotaxus yunnanensis: 10.1021/NP030117B
76186 - Aplysia depilans: 10.1016/0305-0491(84)90180-9
144767 - Aplysia fasciata: 10.1016/0305-0491(84)90180-9
71498 - Aplysia punctata: 10.1016/0305-0491(84)90180-9
3702 - Arabidopsis thaliana: 10.1016/J.PHYTOCHEM.2009.03.021
436207 - Arnica montana: 10.1055/S-0028-1099449
661339 - Aronia melanocarpa: 10.1111/J.1365-2621.1989.TB04709.X
637489 - Artemisia sylvatica: 10.4268/CJCMM20141334
107392 - Ascidia zara: 10.1016/0305-0491(85)90174-9
4686 - Asparagus officinalis: 10.1021/JF00023A019
41972 - Aspleniaceae: 10.1016/0305-1978(85)90030-4
29642 - Asplenium nidus: 10.1016/0305-1978(85)90030-4
1352538 - Asplenium obovatum: 10.1016/0305-1978(85)90030-4
1521210 - Asplenium sulcatum: 10.1016/0305-1978(85)90030-4
78464 - Asplenium trichomanes: 10.1016/0305-1978(85)90030-4
47038 - Astragalus falcatus: 10.1023/B:CONC.0000003427.89093.1F
32110 - Athyrium filix-femina: 10.1016/0305-1978(85)90030-4
28974 - Averrhoa carambola: 10.1016/S0031-9422(00)84040-6
79557 - Barringtonia asiatica: 10.1248/CPB.59.778
78253 - Begonia nantoensis:
161934 - Beta vulgaris: 10.1021/JF00023A019
32073 - Blechnum occidentale: 10.1016/0305-1978(85)90030-4
7091 - Bombyx Mori L.: -
3707 - Brassica juncea: 10.1271/BBB1961.49.1211
3712 - Brassica oleracea:
41496 - Calendula officinalis: 10.1016/0031-9422(80)85055-2
4072 - Capsicum annuum:
85181 - Celastrus orbiculatus: 10.1016/J.PHYTOCHEM.2009.04.018
78064 - Cetraria islandica: 10.1016/0305-1978(87)90002-0
95628 - Cetraria islandica subsp. islandica: 10.1016/0305-1978(87)90002-0
124737 - Cetraria nigricans: 10.1016/0305-1978(87)90002-0
3077 - Chlorella vulgaris:
3082 - Chloroidium saccharophilum: 10.1016/S0031-9422(00)81494-6
34112 - Chlorolobion braunii: 10.1016/S0031-9422(00)81494-6
7719 - Ciona intestinalis: 10.1016/0305-0491(85)90174-9
174050 - Cladonia cenotea: 10.1016/0305-1978(85)90064-X
184094 - Cladonia cornuta: 10.1016/0305-1978(85)90064-X
184097 - Cladonia deformis: 10.1016/0305-1978(85)90064-X
184101 - Cladonia foliacea: 10.1016/0305-1978(88)90082-8
174060 - Cladonia furcata: 10.1016/0305-1978(85)90064-X
174061 - Cladonia glauca: 10.1016/0305-1978(85)90064-X
111668 - Cladonia gracilis:
196765 - Cladonia macilenta: 10.1016/0305-1978(85)90064-X
195774 - Cladonia mitis: 10.1016/0305-1978(85)90064-X
184109 - Cladonia phyllophora: 10.1016/0305-1978(85)90064-X
50943 - Cladonia portentosa: 10.1016/0305-1978(85)90064-X
2031061 - Cladonia ramulosa: 10.1016/0305-1978(85)90064-X
111670 - Cladonia rangiferina: 10.1016/0305-1978(87)90002-0
174071 - Cladonia scabriuscula: 10.1016/0305-1978(85)90064-X
29598 - Coniogramme japonica: 10.1016/0305-1978(85)90030-4
451881 - Corallorhiza trifida: 10.1016/S0031-9422(00)85811-2
141464 - Corbicula japonica: 10.1021/JF058088T
141465 - Corbicula sandai: 10.1021/JF058088T
7959 - Ctenopharyngodon idella: 10.1016/0305-0491(81)90400-4
3659 - Cucumis sativus:
869827 - Cucumis sativus var. sativus:
3661 - Cucurbita maxima: 10.1016/S0031-9422(00)83753-X
3663 - Cucurbita pepo: 10.1021/JF00023A019
714463 - Cyclosorus parasiticus: 10.1016/0305-1978(85)90030-4
4265 - Cynara cardunculus: 10.1021/JF00023A019
84614 - Cyrtomium falcatum: 10.1016/0305-1978(85)90030-4
257571 - Cystoclonium purpureum: 10.1016/S0031-9422(00)85526-0
1328777 - Cystopteris bulbifera: 10.1016/0305-1978(85)90030-4
32112 - Cystopteris fragilis: 10.1016/0305-1978(85)90030-4
872508 - Cystopteris sudetica: 10.1016/0305-1978(85)90030-4
4039 - Daucus carota:
77547 - Desmodesmus abundans: 10.1016/S0031-9422(00)81494-6
35925 - Diospyros kaki:
37432 - Diphasiastrum tristachyum: 10.1016/0305-1978(85)90030-4
6511 - Dolabella auricularia: 10.2331/SUISAN.57.277
239547 - Dryopteris affinis: 10.1016/0305-1978(85)90030-4
239548 - Dryopteris borreri: 10.1016/0305-1978(85)90030-4
239555 - Dryopteris carthusiana: 10.1016/0305-1978(85)90030-4
239607 - Dryopteris wallichiana: 10.1016/0305-1978(85)90030-4
449980 - Epipogium aphyllum: 10.1016/S0031-9422(00)85811-2
3258 - Equisetum arvense: 10.1016/0305-1978(85)90030-4
231680 - Equisetum fluviatile: 10.1016/0305-1978(85)90030-4
3262 - Equisetum hyemale: 10.1016/0305-1978(85)90030-4
113538 - Equisetum palustre: 10.1016/0305-1978(85)90030-4
231681 - Equisetum pratense: 10.1016/0305-1978(85)90030-4
231679 - Equisetum sylvaticum: 10.1016/0305-1978(85)90030-4
3260 - Equisetum telmateia: 10.1016/0305-1978(85)90030-4
568080 - Erythrophleum fordii: 10.1016/J.BMC.2008.09.021
3467 - Eschscholzia californica: 10.1021/NP0000670
212708 - Euonymus japonicus: 10.1271/BBB1961.49.1211
102770 - Eupatorium cannabinum: 10.1055/S-2006-962665
114476 - Gardenia jasminoides Ellis: -
3311 - Ginkgo biloba: 10.1111/J.1438-8677.1992.TB00261.X
3847 - Glycine max: 10.1271/BBB1961.49.1211
32116 - Gymnocarpium dryopteris: 10.1016/0305-1978(85)90030-4
7729 - Halocynthia roretzi:
106335 - Hibiscus syriacus: 10.1021/JF60182A030
7685 - Holothuria tubulosa: 10.1016/0305-0491(84)90180-9
127129 - Impatiens noli-tangere: 10.1002/HLCA.19760590440
161756 - Isatis tinctoria: 10.1016/J.PHYTOCHEM.2009.04.019
4236 - Lactuca sativa: 10.1021/JF00023A019
75943 - Lactuca serriola: 10.1271/BBB1961.49.1211
122810 - Lagerstroemia speciosa: 10.1080/10286020310001596024
89585 - Lemna aequinoctialis: 10.1271/BBB1961.50.2053
161103 - Lemna perpusilla: 10.1271/BBB1961.50.2053
3252 - Lycopodium clavatum: 10.1016/0305-1978(85)90030-4
13608 - Mantoniella squamata: 10.1016/0305-1978(95)00075-5
3371 - Metasequoia glyptostroboides: 10.1016/0305-1978(87)90003-2
148709 - Mimosa aculeaticarpa var. biuncifera: 10.1007/BF00596768
176248 - Monotropa hypopitys: 10.1016/S0031-9422(00)85811-2
167005 - Montanoa speciosa: 10.1016/0031-9422(91)83196-R
48534 - Neottia nidus-avis: 10.1016/S0031-9422(00)85811-2
32153 - Nephrolepis cordifolia: 10.1016/0305-1978(85)90030-4
34165 - Nephrolepis exaltata: 10.1016/0305-1978(85)90030-4
344402 - Nephroselmis rotunda: 10.1016/0305-1978(95)00075-5
4146 - Olea europaea: 10.1002/0471684228.EGP08791
3281 - Onoclea sensibilis: 10.1016/0305-1978(85)90030-4
174658 - Oreopteris limbosperma: 10.1016/0305-1978(85)90030-4
204151 - Orthosiphon aristatus: 10.1007/BF00596668
4726 - Pandanus tectorius: 10.1079/PHN2005892
694377 - Panzerina lanata: 10.1007/S10600-011-0065-4
174403 - Paralithodes brevipes: 10.1248/CPB.54.1462
1259760 - Parlibellus delognei: 10.1021/NP50035A010
48386 - Perilla frutescens: 10.1271/BBB1961.49.1211
179837 - Perilla frutescens var. crispa: 10.1016/J.FCT.2009.10.009
4043 - Petroselinum crispum: 10.1007/BF02258976
3885 - Phaseolus vulgaris:
218620 - Phlebodium aureum: 10.1016/0305-1978(85)90030-4
3329 - Picea abies: 10.1016/S0021-9673(01)84605-7
130377 - Piper aduncum: 10.1021/NP50103A003
1868143 - Pityrogramma sulphurea: 10.1016/0305-1978(85)90030-4
33090 - Plants: -
207866 - Polystichum luctuosum: 10.1016/0305-1978(85)90030-4
207876 - Polystichum tsus-simense: 10.1016/0305-1978(85)90030-4
363316 - Protula tubularia: 10.1016/0305-0491(84)90180-9
122119 - Prunus angustifolia: 10.1021/JF00087A017
36596 - Prunus armeniaca:
3758 - Prunus domestica: 10.1021/JF00087A017
3760 - Prunus persica: 10.1016/S0031-9422(00)81842-7
120290 - Psidium guajava: 10.1021/JF980405R
1129518 - Psychotria correae: 10.1016/0031-9422(94)00823-C
32101 - Pteridium aquilinum: 10.1016/0305-1978(85)90030-4
262952 - Pteris tremula: 10.1016/0305-1978(85)90030-4
859456 - Ramalina capitata: 10.1006/LICH.1995.0012
3447 - Ranunculus acris: 10.1002/HLCA.19760590440
286908 - Ranunculus granatensis: 10.1002/HLCA.19760590440
3726 - Raphanus sativus:
75581 - Rhododendron indicum: 10.1271/BBB1961.49.1211
74635 - Rosa canina:
74645 - Rosa rugosa: 10.1111/J.1365-2621.1989.TB04709.X
267261 - Rosa villosa: 10.1002/HLCA.19830660211
61864 - Sandersonia aurantiaca: 10.1016/S0304-4238(97)00124-6
3089 - Scenedesmus quadricauda: 10.1016/S0031-9422(00)81494-6
4550 - Secale cereale: 10.1515/ZNC-1993-11-1212
30991 - Silurus asotus: 10.1248/CPB.59.140
329782 - Solanum lanceolatum: 10.1055/S-2001-11496
4081 - Solanum lycopersicum: 10.1021/JF00023A019
45837 - Solanum pseudocapsicum: 10.1055/S-2001-11496
4113 - Solanum tuberosum:
3562 - Spinacia oleracea: 10.1021/JF00023A019
32079 - Stenochlaena palustris: 10.1016/S0031-9422(98)00352-5
405089 - Stereocaulon botryosum: 10.1016/0305-1978(87)90002-0
50940 - Stereocaulon paschale: 10.1016/0305-1978(87)90002-0
114457 - Struthiopteris spicant: 10.1016/0305-1978(85)90030-4
7725 - Styela clava: 10.1016/0305-0491(85)90174-9
7726 - Styela plicata: 10.1016/0305-0491(85)90174-9
13708 - Tagetes erecta:
55843 - Tagetes patula:
39993 - Terminalia catappa: 10.1111/J.1365-2621.2001.TB15182.X
281732 - Tethya aurantium: 10.1016/0305-0491(84)90180-9
1689752 - Tetraselmis wettsteinii: 10.1016/0305-1978(95)00075-5
29618 - Thelypteris palustris: 10.1016/0305-1978(85)90030-4
87282 - Umbilicaria rigida: 10.1016/0305-1978(87)90002-0
392743 - Umbilicaria torrefacta: 10.1016/0305-1978(87)90002-0
87287 - Umbilicaria vellea: 10.1016/0305-1978(87)90002-0
225837 - Uvaria lucida: 10.1016/S0031-9422(96)00448-7
13750 - Vaccinium macrocarpon: 10.1021/JF00087A017
180763 - Vaccinium myrtillus: 10.1016/S0168-9452(97)00241-0
214053 - Viola tricolor: 10.1016/0031-9422(80)87027-0
3972 - Viscum album: 10.1055/S-1999-14089
29760 - Vitis vinifera:
4577 - Zea mays: 10.1271/BBB1961.49.1211
44586 - 三七: -
33090 - 枳椇子: -
33090 - 栀子: -
33090 - 浮萍: -
33090 - 白果: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表
Cytoplasm	9	ANG, APOE, CAT, GPX1, GSTP1, NOS2, PIK3CA, PTGS2, TP53
Peripheral membrane protein	2	CYP1B1, PTGS2
Endoplasmic reticulum membrane	2	CYP1B1, PTGS2
Nucleus	6	ANG, APOE, GSTP1, MPO, NOS2, TP53
cytosol	10	ANG, BCO1, CAT, GPX1, GSR, GSTP1, LIPE, NOS2, PIK3CA, TP53
dendrite	1	APOE
centrosome	1	TP53
nucleoplasm	3	MPO, NOS2, TP53
Cell membrane	1	LIPE
lamellipodium	1	PIK3CA
glutamatergic synapse	1	APOE
Golgi apparatus	1	APOE
Golgi membrane	1	INS
growth cone	1	ANG
lysosomal membrane	1	EGF
mitochondrial inner membrane	1	CYP24A1
neuronal cell body	2	ANG, APOE
Cytoplasm, cytosol	3	BCO1, LIPE, NOS2
Lysosome	1	MPO
plasma membrane	4	APOE, EGF, NOS2, PIK3CA
Membrane	6	APOE, CAT, CYP1B1, EGF, LIPE, TP53
caveola	2	LIPE, PTGS2
extracellular exosome	6	APOE, CAT, EGF, GSR, GSTP1, MPO
endoplasmic reticulum	3	APOE, PTGS2, TP53
extracellular space	8	ANG, APOE, CGA, CRP, EGF, GSTP1, INS, MPO
perinuclear region of cytoplasm	2	NOS2, PIK3CA
intercalated disc	1	PIK3CA
mitochondrion	8	BCO2, CAT, CYP1B1, CYP24A1, GPX1, GSR, GSTP1, TP53
protein-containing complex	3	CAT, PTGS2, TP53
intracellular membrane-bounded organelle	3	CAT, CYP1B1, MPO
Microsome membrane	2	CYP1B1, PTGS2
Secreted	5	ANG, APOE, CGA, CRP, INS
extracellular region	9	ANG, APOE, CAT, CGA, CRP, EGF, GSTP1, INS, MPO
Mitochondrion matrix	1	TP53
mitochondrial matrix	5	BCO2, CAT, GPX1, GSR, TP53
transcription regulator complex	1	TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome	1	TP53
external side of plasma membrane	1	GSR
Endosome, multivesicular body	1	APOE
Extracellular vesicle	1	APOE
Secreted, extracellular space, extracellular matrix	1	APOE
chylomicron	1	APOE
high-density lipoprotein particle	1	APOE
low-density lipoprotein particle	1	APOE
multivesicular body	1	APOE
very-low-density lipoprotein particle	1	APOE
actin cytoskeleton	1	ANG
nucleolus	2	ANG, TP53
Cytoplasm, P-body	1	NOS2
P-body	1	NOS2
Early endosome	1	APOE
vesicle	1	GSTP1
Cytoplasm, perinuclear region	1	NOS2
Cytoplasm, cytoskeleton	1	TP53
focal adhesion	1	CAT
extracellular matrix	1	APOE
Peroxisome	2	CAT, NOS2
basement membrane	1	ANG
Peroxisome matrix	1	CAT
peroxisomal matrix	2	CAT, NOS2
peroxisomal membrane	1	CAT
Nucleus, PML body	1	TP53
PML body	1	TP53
collagen-containing extracellular matrix	1	APOE
secretory granule	1	MPO
Nucleus inner membrane	1	PTGS2
Nucleus outer membrane	1	PTGS2
nuclear inner membrane	1	PTGS2
nuclear outer membrane	1	PTGS2
neuron projection	1	PTGS2
chromatin	1	TP53
Chromosome	1	ANG
Secreted, extracellular space	1	APOE
Nucleus, nucleolus	1	ANG
blood microparticle	1	APOE
site of double-strand break	1	TP53
endosome lumen	1	INS
Lipid droplet	1	LIPE
Membrane, caveola	1	LIPE
Melanosome	1	APOE
Cytoplasm, Stress granule	1	ANG
cytoplasmic stress granule	1	ANG
germ cell nucleus	1	TP53
replication fork	1	TP53
azurophil granule	1	MPO
ficolin-1-rich granule lumen	2	CAT, GSTP1
secretory granule lumen	3	CAT, GSTP1, INS
Golgi lumen	2	CGA, INS
endoplasmic reticulum lumen	3	APOE, INS, PTGS2
nuclear matrix	1	TP53
transcription repressor complex	1	TP53
platelet alpha granule lumen	1	EGF
phosphatidylinositol 3-kinase complex	1	PIK3CA
phosphatidylinositol 3-kinase complex, class IA	1	PIK3CA
endocytic vesicle	1	ANG
transport vesicle	1	INS
azurophil granule lumen	1	MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane	1	INS
clathrin-coated endocytic vesicle membrane	2	APOE, EGF
phagocytic vesicle lumen	1	MPO
[Isoform 1]: Nucleus	1	TP53
synaptic cleft	1	APOE
discoidal high-density lipoprotein particle	1	APOE
endocytic vesicle lumen	1	APOE
follicle-stimulating hormone complex	1	CGA
pituitary gonadotropin complex	1	CGA
chylomicron remnant	1	APOE
intermediate-density lipoprotein particle	1	APOE
lipoprotein particle	1	APOE
multivesicular body, internal vesicle	1	APOE
cortical cytoskeleton	1	NOS2
angiogenin-PRI complex	1	ANG
catalase complex	1	CAT
TRAF2-GSTP1 complex	1	GSTP1
phosphatidylinositol 3-kinase complex, class IB	1	PIK3CA

文献列表

Zhilei Qin, Mengsu Liu, Xuefeng Ren, Weizhu Zeng, Zhengshan Luo, Jingwen Zhou. De Novo Biosynthesis of Lutein in Yarrowia lipolytica. Journal of agricultural and food chemistry. 2024 Mar; 72(10):5348-5357. doi: 10.1021/acs.jafc.3c09080. [PMID: 38412053]
Jolanta Flieger, Natalia Żuk, Sylwia Pasieczna-Patkowska, Marcin Kuśmierz, Rafał Panek, Wojciech Franus, Jacek Baj, Grzegorz Buszewicz, Grzegorz Teresiński, Wojciech Płaziński. Selective Removal of Chlorophyll and Isolation of Lutein from Plant Extracts Using Magnetic Solid Phase Extraction with Iron Oxide Nanoparticles. International journal of molecular sciences. 2024 Mar; 25(6):. doi: 10.3390/ijms25063152. [PMID: 38542125]
María Dolores Requena-Ramírez, Cristina Rodríguez-Suárez, Dámaso Hornero-Méndez, Sergio G Atienza. Lutein esterification increases carotenoid retention in durum wheat grain. A step further in breeding and improving the commercial and nutritional quality during grain storage. Food chemistry. 2024 Mar; 435(?):137660. doi: 10.1016/j.foodchem.2023.137660. [PMID: 37832338]
Veronika Gunjević, Mirta Majerić Musa, Dora Zurak, Zlatko Svečnjak, Marija Duvnjak, Darko Grbeša, Kristina Kljak. Carotenoid degradation rate in milled grain of dent maize hybrids and its relationship with the grain physicochemical properties. Food research international (Ottawa, Ont.). 2024 Feb; 177(?):113909. doi: 10.1016/j.foodres.2023.113909. [PMID: 38225147]
Jiawen Yan, Zhihui Liu, Tongtong Wang, Ruoman Wang, Shuya Wang, Weijie Chen, Jinwei Suo, Jingwei Yan, Jiasheng Wu. TgLUT1 regulated by TgWRKY10 enhances the tolerance of Torreya grandis to drought stress. Plant physiology and biochemistry : PPB. 2024 Feb; 207(?):108436. doi: 10.1016/j.plaphy.2024.108436. [PMID: 38367388]
Weidong Chen, Yuanqing Li, Min Li, Hai Li, Caifang Chen, Yanzhao Lin. Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014. Journal of health, population, and nutrition. 2024 Feb; 43(1):20. doi: 10.1186/s41043-024-00511-9. [PMID: 38303096]
Grzegorz Dąbrowski, Sylwester Czaplicki, Marcin Szustak, Eliza Korkus, Edyta Gendaszewska-Darmach, Iwona Konopka. The impact of selected xanthophylls on oil hydrolysis by pancreatic lipase: in silico and in vitro studies. Scientific reports. 2024 02; 14(1):2731. doi: 10.1038/s41598-024-53312-9. [PMID: 38302772]
Emilia Reszczyńska, Anna Wiśniewska-Becker, Mariusz Duda, Alicja Sęk, Wiesław I Gruszecki, Agnieszka Hanaka. The presence of free palmitic acid modulates the effects of lutein on structural and dynamic properties of lipid membranes. Archives of biochemistry and biophysics. 2024 Feb; 752(?):109883. doi: 10.1016/j.abb.2024.109883. [PMID: 38211638]
Sharayah Carter, Alison M Hill, Catherine Yandell, Jonathan D Buckley, Alison M Coates. Study protocol for a 15-week randomised controlled trial assessing the independent effects of high-cholesterol and high-saturated fat diets on LDL cholesterol. BMJ open. 2024 01; 14(1):e081664. doi: 10.1136/bmjopen-2023-081664. [PMID: 38272555]
Hideo Takekoshi, Masaki Fujishima, Taiki Miyazawa, Ohki Higuchi, Takahiko Fujikawa, Teruo Miyazawa. Simultaneous Intake of Chlorella and Ascidian Ethanolamine Plasmalogen Accelerates Activation of BDNF-TrkB-CREB Signaling in Rats. Molecules (Basel, Switzerland). 2024 Jan; 29(2):. doi: 10.3390/molecules29020357. [PMID: 38257270]
Qing Liu, Chenyun Miao, Fangxuan Lin, Han Zhang, Qin Zhang. A case-control retrospective study for the effect of Shoutai Wan on IVF-ET pregnancy outcome. Medicine. 2024 Jan; 103(1):e36846. doi: 10.1097/md.0000000000036846. [PMID: 38181258]
Yang Meng, Yuanhui Wang, Weimin Guo, Ke Lei, Zuxiao Chen, Hang Xu, Aiguo Wang, Qiang Xu, Jianjun Liu, Qiang Zeng. Analysis of the relationship between color and natural pigments of tobacco leaves during curing. Scientific reports. 2024 01; 14(1):166. doi: 10.1038/s41598-023-50801-1. [PMID: 38167588]
Zhenhua Xu, Haiying Liu, Yanmin Yu, Dawei Gao, Chunxu Leng, Shuli Zhang, Ping Yan. MWCNTs Alleviated saline-alkali stress by optimizing photosynthesis and sucrose metabolism in rice seedling. Plant signaling & behavior. 2023 Dec; 18(1):2283357. doi: 10.1080/15592324.2023.2283357. [PMID: 38053501]
Serafino Suriano, Pasquale Codianni, Anna Iannucci. Carotenoids and tocols comparison in different Subspecies of Triticum turgidum and aestivum. Food research international (Ottawa, Ont.). 2023 Dec; 174(Pt 1):113620. doi: 10.1016/j.foodres.2023.113620. [PMID: 37986473]
Shaohua Yan, Siyu Chen, Yumiao Liu, Hongbin Liang, Xinlu Zhang, Qiuxia Zhang, Jiancheng Xiu. Associations of serum carotenoids with visceral adiposity index and lipid accumulation product: a cross-sectional study based on NHANES 2001-2006. Lipids in health and disease. 2023 Nov; 22(1):209. doi: 10.1186/s12944-023-01945-6. [PMID: 38037060]
Jadwiga Hamulka, Agnieszka Sulich, Magdalena Górnicka, Marta Jeruszka-Bielak. Changes in Plasma Carotenoid Concentrations during the AntioxObesity Weight Reduction Program among Adults with Excessive Body Weight. Nutrients. 2023 Nov; 15(23):. doi: 10.3390/nu15234890. [PMID: 38068747]
Dieudonné M Dansou, Han Chen, Yanan Yu, Youyou Yang, Isabelle N Tchana, Liyuan Zhao, Chaohua Tang, Qingyu Zhao, Yuchang Qin, Junmin Zhang. Enrichment efficiency of lutein in eggs and its function in improving fatty liver hemorrhagic syndrome in aged laying hens. Poultry science. 2023 Nov; 103(2):103286. doi: 10.1016/j.psj.2023.103286. [PMID: 38100949]
Yang Liu, Guanlin Yang, Shiqiao Huo, Jiabi Wu, Ping Ren, Yonggang Cao, Jingquan Gao, Liquan Tong, Dongyu Min. Lutein suppresses ferroptosis of cardiac microvascular endothelial cells via positive regulation of IRF in cardiac hypertrophy. European journal of pharmacology. 2023 Nov; 959(?):176081. doi: 10.1016/j.ejphar.2023.176081. [PMID: 37797674]
Altevir Rossato Viana, Isadora Nicola, Camila Franco, Patrícia Acosta Caetano, Eduardo Jacob-Lopes, Leila Queiroz Zepka, Daniel Santos, Erico Marlon Moraes Flores, Bruno Stefanello Vizzotto, Katianne Wolf, Aline Ferreira Ourique, Sergio Roberto Mortari, Cristiano Rodrigo Bohn Rhoden, Luciana Maria Fontanari Krause. Phytochemical characterization and toxicological activity attributed to the acetonic extract of South American Vassobia breviflora. Journal of toxicology and environmental health. Part A. 2023 Nov; 86(21):816-832. doi: 10.1080/15287394.2023.2254316. [PMID: 37667472]
Kodai Ueno, Tetsuya Matsushita, Monami Sugihara, Kohei Yamada, Hideyuki Sato, Satomi Onoue. Solid lipid nanoparticles of lutein with improved dissolution behavior and oral absorption. Pharmaceutical development and technology. 2023 Nov; 28(9):877-883. doi: 10.1080/10837450.2023.2270032. [PMID: 37828716]
Xiangdong Wang, Xiaojie Liu, Xiaowen Wang, Haiying Wang, Li-Hua Zhang, Huijuan Yu, Wenzhi Yang, Hong-Hua Wu. Carotenoid-derived norsesquiterpenoids and sesquiterpenoids from Tagetes erecta L. Phytochemistry. 2023 Nov; 215(?):113860. doi: 10.1016/j.phytochem.2023.113860. [PMID: 37714249]
Neha Tanwar, James E Rookes, David M Cahill, Sangram K Lenka. Carotenoid Pathway Engineering in Tobacco Chloroplast Using a Synthetic Operon. Molecular biotechnology. 2023 Nov; 65(11):1923-1934. doi: 10.1007/s12033-023-00693-3. [PMID: 36884112]
Kristina Likkei, Marcus Moldenhauer, Neslihan N Tavraz, Eugene G Maksimov, Nikolai N Sluchanko, Thomas Friedrich. Lipid composition and properties affect protein-mediated carotenoid uptake efficiency from membranes. Biochimica et biophysica acta. Biomembranes. 2023 Oct; ?(?):184241. doi: 10.1016/j.bbamem.2023.184241. [PMID: 37866690]
Li Liang, Yu Liu, Junlong Zhu, Chaoting Wen, Xiaofang Liu, Jixian Zhang, Youdong Li, Guoyan Liu, Xin Xu. Improving the Physicochemical Stability of Soy Phospholipid-Stabilized Emulsions Loaded with Lutein by the Addition of Sphingomyelin and Cholesterol: Inspired by a Milk Fat Globule Membrane. Journal of agricultural and food chemistry. 2023 Oct; ?(?):. doi: 10.1021/acs.jafc.3c04770. [PMID: 37815121]
Maria Sulli, Luca Dall'Osto, Paola Ferrante, Zeno Guardini, Rodrigo Lionel Gomez, Paola Mini, Olivia Costantina Demurtas, Giuseppe Aprea, Alessandro Nicolia, Roberto Bassi, Giovanni Giuliano. Generation and physiological characterization of genome-edited Nicotiana benthamiana plants containing zeaxanthin as the only leaf xanthophyll. Planta. 2023 Oct; 258(5):93. doi: 10.1007/s00425-023-04248-3. [PMID: 37796356]
Hongtao Wang, Yuchen Tian, Yuxing Li, Jiaqi Wei, Fengwang Ma, Wei Liang, Cuiying Li. Analysis of Carotenoids and Gene Expression in Apple Germplasm Resources Reveals the Role of MdCRTISO and MdLCYE in the Accumulation of Carotenoids. Journal of agricultural and food chemistry. 2023 Oct; ?(?):. doi: 10.1021/acs.jafc.3c04453. [PMID: 37796201]
Corinne N Cannavale, Shelby A Keye, Laura M Rosok, Shelby G Martell, Tori A Holthaus, Lauren R Raine, Sean P Mullen, Hannah D Holscher, Charles H Hillman, Arthur F Kramer, Neal J Cohen, Billy R Hammond, Lisa Renzi-Hammond, Naiman A Khan. Macular Pigment Optical Density and Skin Carotenoids in a Childhood Sample. The Journal of nutrition. 2023 10; 153(10):3144-3151. doi: 10.1016/j.tjnut.2023.06.006. [PMID: 37315793]
Anil Kumar Patel, Akash Pralhad Vadrale, Reeta-Rani Singhania, Chiu-Wen Chen, Jo Shu Chang, Cheng-Di Dong. Enhanced mixotrophic production of lutein and lipid from potential microalgae isolate Chlorella sorokiniana C16. Bioresource technology. 2023 Oct; 386(?):129477. doi: 10.1016/j.biortech.2023.129477. [PMID: 37437816]
Gaoshuai Zhang, Meijing Zhang, Yiqiao Pei, Kun Qian, Jiao Xie, Qun Huang, Suwen Liu, Na Xue, Yujiao Zu, Hao Wang. Enhancing stability of liposomes using high molecular weight chitosan to promote antioxidative stress effects and lipid-lowering activity of encapsulated lutein in vivo and in vitro. International journal of biological macromolecules. 2023 Sep; ?(?):126564. doi: 10.1016/j.ijbiomac.2023.126564. [PMID: 37714230]
Nancy E Moran, Joshua Wade, Rachel Stroh, Barbara Stoll, Gregory Guthrie, Amy B Hair, Douglas G Burrin. Preterm Pigs Fed Donor Human Milk Have Greater Liver Beta-carotene Concentrations than Pigs Fed Infant Formula. The Journal of nutrition. 2023 Sep; ?(?):. doi: 10.1016/j.tjnut.2023.08.026. [PMID: 37666415]
Jia-Yi Lin, I-Son Ng. Enhanced carbon capture, lipid and lutein production in Chlamydomonas reinhardtii under meso-thermophilic conditions using chaperone and CRISPRi system. Bioresource technology. 2023 Sep; 384(?):129340. doi: 10.1016/j.biortech.2023.129340. [PMID: 37343802]
Stephanie Bethmann, Ann-Kathrin Haas, Michael Melzer, Peter Jahns. The impact of long-term acclimation to different growth light intensities on the regulation of zeaxanthin epoxidase in different plant species. Physiologia plantarum. 2023 Sep; 175(5):e13998. doi: 10.1111/ppl.13998. [PMID: 37882279]
Yuanyuan Li, Bingxue Liu, Xiaoxue Zhang, Yanjie Liu, Siying Wang, Shujun Li, Xiuhua Zhao. Lutein-stachyose (LS) amphiphilic oligosaccharide derivatives improve the oral bioavailability of lutein. Food chemistry. 2023 Aug; 418(?):136032. doi: 10.1016/j.foodchem.2023.136032. [PMID: 36996657]
Mari Carmen Ruiz-Domínguez, María Robles, Lidia Martín, Álvaro Beltrán, Riccardo Gava, María Cuaresma, Francisco Navarro, Carlos Vílchez. Ultrasound-Based Recovery of Anti-Inflammatory and Antimicrobial Extracts of the Acidophilic Microalga Coccomyxa onubensis. Marine drugs. 2023 Aug; 21(9):. doi: 10.3390/md21090471. [PMID: 37755084]
Justyna Widomska, Witold K Subczynski, Renata Welc-Stanowska, Rafal Luchowski. An Overview of Lutein in the Lipid Membrane. International journal of molecular sciences. 2023 Aug; 24(16):. doi: 10.3390/ijms241612948. [PMID: 37629129]
Fahrul Nurkolis, Nurpudji Astuti Taslim, Hardinsyah Hardinsyah. The importance of lutein-plant based nanoencapsulation studies - An effort to improve clinical studies on the stability and bioaccessibility of lutein for health vision. Clinical nutrition ESPEN. 2023 08; 56(?):81-82. doi: 10.1016/j.clnesp.2023.05.008. [PMID: 37344087]
Ramóna Pap, Edina Pandur, Gergely Jánosa, Katalin Sipos, Ferenc Rómeó Fritz, Tamás Nagy, Attila Agócs, József Deli. Protective Effects of 3'-Epilutein and 3'-Oxolutein against Glutamate-Induced Neuronal Damage. International journal of molecular sciences. 2023 Jul; 24(15):. doi: 10.3390/ijms241512008. [PMID: 37569384]
Eun-A Kim, Nalae Kang, Seong-Young Heo, Jae-Young Oh, Seung-Hong Lee, Seon-Heui Cha, Won-Keun Kim, Soo-Jin Heo. Antioxidant, Antiviral, and Anti-Inflammatory Activities of Lutein-Enriched Extract of Tetraselmis Species. Marine drugs. 2023 Jun; 21(7):. doi: 10.3390/md21070369. [PMID: 37504900]
Galina Brychkova, Cleiton Lourenço de Oliveira, Luiz Antonio Augusto Gomes, Matheus de Souza Gomes, Antoine Fort, Alberto Abrantes Esteves-Ferreira, Ronan Sulpice, Peter C McKeown, Charles Spillane. Regulation of Carotenoid Biosynthesis and Degradation in Lettuce (Lactuca sativa L.) from Seedlings to Harvest. International journal of molecular sciences. 2023 Jun; 24(12):. doi: 10.3390/ijms241210310. [PMID: 37373458]
Rihui Li, Qinyu Zeng, Xiangxiang Zhang, Jing Jing, Xiaoyu Ge, Lun Zhao, Bin Yi, Jinxing Tu, Tingdong Fu, Jing Wen, Jinxiong Shen. Xanthophyll esterases in association with fibrillins control the stable storage of carotenoids in yellow flowers of rapeseed (Brassica juncea). The New phytologist. 2023 May; ?(?):. doi: 10.1111/nph.18970. [PMID: 37194444]
Ming-Hua Liang, Shan-Rong Xie, Hao-Hong Chen, Jian-Guo Jiang. DbMADS regulates carotenoid metabolism by repressing two carotenogenic genes in the green alga Dunaliella sp. FACHB-847. Journal of cellular physiology. 2023 Apr; ?(?):. doi: 10.1002/jcp.31017. [PMID: 37087727]
Wenjing Su, Wenhao Xu, Enshuo Liu, Weike Su, Nikolay E Polyakov. Improving the Treatment Effect of Carotenoids on Alzheimer's Disease through Various Nano-Delivery Systems. International journal of molecular sciences. 2023 Apr; 24(8):. doi: 10.3390/ijms24087652. [PMID: 37108814]
Wason Parklak, Sakaewan Ounjaijean, Kanokwan Kulprachakarn, Kongsak Boonyapranai. In Vitro α-Amylase and α-Glucosidase Inhibitory Effects, Antioxidant Activities, and Lutein Content of Nine Different Cultivars of Marigold Flowers (Tagetes spp.). Molecules (Basel, Switzerland). 2023 Apr; 28(8):. doi: 10.3390/molecules28083314. [PMID: 37110550]
Rudy Kurniawan, Fahrul Nurkolis, Nurpudji Astuti Taslim, Dionysius Subali, Reggie Surya, William Ben Gunawan, Darmawan Alisaputra, Nelly Mayulu, Netty Salindeho, Bonglee Kim. Carotenoids Composition of Green Algae Caulerpa racemosa and Their Antidiabetic, Anti-Obesity, Antioxidant, and Anti-Inflammatory Properties. Molecules (Basel, Switzerland). 2023 Apr; 28(7):. doi: 10.3390/molecules28073267. [PMID: 37050034]
Petar Šušnjara, Zrinka Mihaljević, Ana Stupin, Nikolina Kolobarić, Anita Matić, Ivana Jukić, Zlata Kralik, Gordana Kralik, Anđelina Miloloža, Tihana Pavošević, Vatroslav Šerić, Zdenko Lončarić, Darko Kerovec, Olivera Galović, Ines Drenjančević. Consumption of Nutritionally Enriched Hen Eggs Enhances Endothelium-Dependent Vasodilation via Cyclooxygenase Metabolites in Healthy Young People-A Randomized Study. Nutrients. 2023 Mar; 15(7):. doi: 10.3390/nu15071599. [PMID: 37049437]
Corinne N Cannavale, Caitlyn G Edwards, Ruyu Liu, Shelby A Keye, Samantha J Iwinski, Hannah D Holscher, Lisa Renzi-Hammond, Naiman A Khan. Macular pigment is inversely related to circulating C-reactive protein concentrations in school-aged children. Nutrition research (New York, N.Y.). 2023 Mar; 114(?):13-19. doi: 10.1016/j.nutres.2023.03.003. [PMID: 37149925]
Shuang Han, Yunjing Wang, Qingchen Zhang, Wenjing Wang, Dongli Pei. Chrysanthemum morifolium β-carotene hydroxylase overexpression promotes Arabidopsis thaliana tolerance to high light stress. Journal of plant physiology. 2023 Mar; 284(?):153962. doi: 10.1016/j.jplph.2023.153962. [PMID: 36940578]
Caterina D'Ambrosio, Adriana Lucia Stigliani, José L Rambla, Sarah Frusciante, Gianfranco Diretto, Eugenia M A Enfissi, Antonio Granell, Paul D Fraser, Giovanni Giorio. A xanthophyll-derived apocarotenoid regulates carotenogenesis in tomato chromoplasts. Plant science : an international journal of experimental plant biology. 2023 Mar; 328(?):111575. doi: 10.1016/j.plantsci.2022.111575. [PMID: 36572066]
Xin Shu, Liang Zhang, Wenyan Liao, Jinfang Liu, Like Mao, Fang Yuan, Yanxiang Gao. Nanostructured lipid carriers (NLCs) stabilized by natural or synthetic emulsifiers for lutein delivery: Improved physicochemical stability, antioxidant activity, and bioaccessibility. Food chemistry. 2023 Mar; 403(?):134465. doi: 10.1016/j.foodchem.2022.134465. [PMID: 36358082]
Jan Neelissen, Per Leanderson, Lena Jonasson, Rosanna W S Chung. The Effects of Dairy and Plant-Based Liquid Components on Lutein Liberation in Spinach Smoothies. Nutrients. 2023 Feb; 15(3):. doi: 10.3390/nu15030779. [PMID: 36771485]
Mahsa Mekanik, Reza Fotovat, Ehsan Motamedian, Vahab Jafarian. Improvement of Lutein Production in Auxenochlorella protothecoides Using Its Genome-Scale Metabolic Model and a System-Oriented Approach. Applied biochemistry and biotechnology. 2023 Feb; 195(2):889-904. doi: 10.1007/s12010-022-04186-y. [PMID: 36222987]
Fatemeh Ghasemi, Fatemeh Navab, Mohammad Hossein Rouhani, Pegah Amini, Nafiseh Shokri-Mashhadi. The effect of lutein and Zeaxanthine on dyslipidemia: A meta-analysis study. Prostaglandins & other lipid mediators. 2023 Feb; 164(?):106691. doi: 10.1016/j.prostaglandins.2022.106691. [PMID: 36336325]
Akash Pralhad Vadrale, Cheng-Di Dong, Dibyajyoti Haldar, Chien-Hui Wu, Chiu-Wen Chen, Reeta Rani Singhania, Anil Kumar Patel. Bioprocess development to enhance biomass and lutein production from Chlorella sorokiniana Kh12. Bioresource technology. 2023 Feb; 370(?):128583. doi: 10.1016/j.biortech.2023.128583. [PMID: 36610481]
Qi Bian, Xue Jiao, Ye Chen, Hongwei Yu, Lidan Ye. Hierarchical dynamic regulation of Saccharomyces cerevisiae for enhanced lutein biosynthesis. Biotechnology and bioengineering. 2023 02; 120(2):536-552. doi: 10.1002/bit.28286. [PMID: 36369967]
Veronika Nagy, Attila Agócs, Viktória L Balázs, Dragica Purger, Rita Filep, Viktor Sándor, Erika Turcsi, Gergely Gulyás-Fekete, József Deli. Lutein Isomers: Preparation, Separation, Structure Elucidation, and Occurrence in 20 Medicinal Plants. Molecules (Basel, Switzerland). 2023 Jan; 28(3):. doi: 10.3390/molecules28031187. [PMID: 36770852]
Antonela Ninčević Grassino, Suzana Rimac Brnčić, Marija Badanjak Sabolović, Jana Šic Žlabur, Roko Marović, Mladen Brnčić. Carotenoid Content and Profiles of Pumpkin Products and By-Products. Molecules (Basel, Switzerland). 2023 Jan; 28(2):. doi: 10.3390/molecules28020858. [PMID: 36677916]
Sowmya Shree Gopal, Shinde Vijay Sukhdeo, Baskaran Vallikannan, Ganesan Ponesakki. Lutein ameliorates high-fat diet-induced obesity, fatty liver, and glucose intolerance in C57BL/6J mice. Phytotherapy research : PTR. 2023 Jan; 37(1):329-341. doi: 10.1002/ptr.7615. [PMID: 36086831]
C Laurent, H Caillat, C L Girard, A Ferlay, S Laverroux, J Jost, B Graulet. Impacts of production conditions on goat milk vitamin, carotenoid contents and colour indices. Animal : an international journal of animal bioscience. 2023 Jan; 17(1):100683. doi: 10.1016/j.animal.2022.100683. [PMID: 36610084]
Nisha Chouhan, Ranay Mohan Yadav, Jayendra Pandey, Rajagopal Subramanyam. High light-induced changes in thylakoid supercomplexes organization from cyclic electron transport mutants of Chlamydomonas reinhardtii. Biochimica et biophysica acta. Bioenergetics. 2023 01; 1864(1):148917. doi: 10.1016/j.bbabio.2022.148917. [PMID: 36108725]
Sajad Pirsa, Mitra Mahmudi, Ali Ehsani. Biodegradable film based on cress seed mucilage, modified with lutein, maltodextrin and alumina nanoparticles: Physicochemical properties and lutein controlled release. International journal of biological macromolecules. 2023 Jan; 224(?):1588-1599. doi: 10.1016/j.ijbiomac.2022.10.244. [PMID: 36346259]
Farouk K El-Baz, Abeer Salama, Sami I Ali, Rania Elgohary. Lutein isolated from Scenedesmus obliquus microalga boosts immunity against cyclophosphamide-induced brain injury in rats. Scientific reports. 2022 12; 12(1):22601. doi: 10.1038/s41598-022-25252-9. [PMID: 36585479]
Petar Šušnjara, Nikolina Kolobarić, Anita Matić, Zrinka Mihaljević, Ana Stupin, Saška Marczi, Ines Drenjančević. Consumption of Hen Eggs Enriched with n-3 Polyunsaturated Fatty Acids, Selenium, Vitamin E and Lutein Incites Anti-Inflammatory Conditions in Young, Healthy Participants - A Randomized Study. Frontiers in bioscience (Landmark edition). 2022 12; 27(12):332. doi: 10.31083/j.fbl2712332. [PMID: 36624951]
Wei Chen, Hua Zhang, Guishan Liu, Ji Kang, Biao Wang, Jilite Wang, Jing Li, Hao Wang. Lutein attenuated methylglyoxal-induced oxidative damage and apoptosis in PC12 cells via the PI3K/Akt signaling pathway. Journal of food biochemistry. 2022 12; 46(12):e14382. doi: 10.1111/jfbc.14382. [PMID: 36017617]
Nikolai N Sluchanko, Yury B Slonimskiy, Nikita A Egorkin, Larisa A Varfolomeeva, Sergey Yu Kleymenov, Mikhail E Minyaev, Yaroslav V Faletrov, Anastasia M Moysenovich, Evgenia Yu Parshina, Thomas Friedrich, Eugene G Maksimov, Konstantin M Boyko, Vladimir O Popov. Structural basis for the carotenoid binding and transport function of a START domain. Structure (London, England : 1993). 2022 12; 30(12):1647-1659.e4. doi: 10.1016/j.str.2022.10.007. [PMID: 36356587]
Shanyong Wang, Wenhua Gao, Yuhan Wang, Tao Song, Haisong Qi, Zhouyang Xiang. Emulsifying properties of naturally acetylated xylans and their application in lutein delivery emulsion. Carbohydrate polymers. 2022 Nov; 296(?):119927. doi: 10.1016/j.carbpol.2022.119927. [PMID: 36088023]
Alexander Montoya-Arroyo, Camilo Toro-González, Nadine Sus, Jorge Warner, Patricia Esquivel, Víctor M Jiménez, Jan Frank. Vitamin E and carotenoid profiles in leaves, stems, petioles and flowers of stinging nettle (Urtica leptophylla Kunth) from Costa Rica. Journal of the science of food and agriculture. 2022 Nov; 102(14):6340-6348. doi: 10.1002/jsfa.11985. [PMID: 35527679]
Anil Kumar Patel, Prashant Kumar, Chiu-Wen Chen, Vaibhav Sunil Tambat, Thanh-Binh Nguyen, Chih-Yao Hou, Jo-Shu Chang, Cheng-Di Dong, Reeta Rani Singhania. Nano magnetite assisted flocculation for efficient harvesting of lutein and lipid producing microalgae biomass. Bioresource technology. 2022 Nov; 363(?):128009. doi: 10.1016/j.biortech.2022.128009. [PMID: 36162780]
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Hamdy Elsayed Ahmed Ali, Fritz Vorisek, Scot E Dowd, Stephanie Kesner, Yang Song, Dali Qian, Mark Crocker. Formation of Lutein, β-Carotene and Astaxanthin in a Coelastrella sp. Isolate. Molecules (Basel, Switzerland). 2022 Oct; 27(20):. doi: 10.3390/molecules27206950. [PMID: 36296546]
Zilong Zhao, Jing Chen, FangFang Ci, He Pang, Ning Cheng, Aijia Xing. α-Carotene: a valuable carotenoid in biological and medical research. Journal of the science of food and agriculture. 2022 Oct; 102(13):5606-5617. doi: 10.1002/jsfa.11966. [PMID: 35478460]
Liyan Zhu, Hui Gao, Linpin Li, Yong Zhang, Yongteng Zhao, Xuya Yu. Promoting lutein production from the novel alga Acutodesmus sp. by melatonin induction. Bioresource technology. 2022 Oct; 362(?):127818. doi: 10.1016/j.biortech.2022.127818. [PMID: 36041678]
Ningxiang Yu, Shengxin Shao, Weiwei Huan, Qin Ye, Xiaohua Nie, Yuanchao Lu, Xianghe Meng. Preparation of novel self-assembled albumin nanoparticles from Camellia seed cake waste for lutein delivery. Food chemistry. 2022 Sep; 389(?):133032. doi: 10.1016/j.foodchem.2022.133032. [PMID: 35490515]
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Ioulia Georgiopoulou, Soultana Tzima, Vasiliki Louli, Kostis Magoulas. Supercritical CO2 Extraction of High-Added Value Compounds from Chlorella vulgaris: Experimental Design, Modelling and Optimization. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27185884. [PMID: 36144617]
Sachin Vyas, Alok Patel, Eric Nabil Risse, Eleni Krikigianni, Ulrika Rova, Paul Christakopoulos, Leonidas Matsakas. Biosynthesis of microalgal lipids, proteins, lutein, and carbohydrates using fish farming wastewater and forest biomass under photoautotrophic and heterotrophic cultivation. Bioresource technology. 2022 Sep; 359(?):127494. doi: 10.1016/j.biortech.2022.127494. [PMID: 35724910]
Canying Li, Jie Zhu, Yuan Cheng, Jiabao Hou, Lei Sun, Yonghong Ge. Acibenzolar-S-methyl activates mitogen-activated protein kinase cascade to mediate chlorophyll and carotenoid metabolisms in the exocarp of Docteur Jules Guyot pears. Journal of the science of food and agriculture. 2022 Aug; 102(11):4435-4445. doi: 10.1002/jsfa.11797. [PMID: 35092628]
Lu He, Lu Cheng, Junjie Wang, Jing Liu, Jinjin Cheng, Zhirong Yang, Rui Cao, Yuanhuai Han, Hongying Li, Bin Zhang. Carotenoid Cleavage Dioxygenase 1 Catalyzes Lutein Degradation To Influence Carotenoid Accumulation and Color Development in Foxtail Millet Grains. Journal of agricultural and food chemistry. 2022 Aug; 70(30):9283-9294. doi: 10.1021/acs.jafc.2c01951. [PMID: 35876162]
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Yury B Slonimskiy, Nikita A Egorkin, Aleksandr A Ashikhmin, Thomas Friedrich, Eugene G Maksimov, Nikolai N Sluchanko. Reconstitution of the functional Carotenoid-Binding Protein from silkworm in E. coli. International journal of biological macromolecules. 2022 Aug; 214(?):664-671. doi: 10.1016/j.ijbiomac.2022.06.135. [PMID: 35753519]
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Caitlyn G Edwards, Anne M Walk, Sharon V Thompson, Ginger E Reeser, Ryan N Dilger, John W Erdman, Nicholas A Burd, Hannah D Holscher, Naiman A Khan. Dietary lutein plus zeaxanthin and choline intake is interactively associated with cognitive flexibility in middle-adulthood in adults with overweight and obesity. Nutritional neuroscience. 2022 Jul; 25(7):1437-1452. doi: 10.1080/1028415x.2020.1866867. [PMID: 33448903]
Rijo Hayashi, Shimmin Hayashi, Shigeki Machida. Changes in Aqueous Humor Lutein Levels of Patients with Cataracts after a 6-Week Course of Lutein-Containing Antioxidant Supplementation. Current eye research. 2022 07; 47(7):1016-1023. doi: 10.1080/02713683.2022.2059811. [PMID: 35392749]
Christian Emmanuel Mahavy, Adeline Mol, Blandine Andrianarisoa, Pierre Duez, Mondher El Jaziri, Marie Baucher, Tsiry Rasamiravaka. The Xanthophyll Carotenoid Lutein Reduces the Invasive Potential of Pseudomonas aeruginosa and Increases Its Susceptibility to Tobramycin. International journal of molecular sciences. 2022 Jun; 23(13):. doi: 10.3390/ijms23137199. [PMID: 35806201]
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Nagashree Shamarao, Mukunda Chethankumar. Antiobesity drug-likeness properties and pancreatic lipase inhibition of a novel low molecular weight lutein oxidized product, LOP6. Food & function. 2022 Jun; 13(11):6036-6055. doi: 10.1039/d1fo04064b. [PMID: 35615990]
Selly D Msungu, Arnold A Mushongi, Pavithravani B Venkataramana, Ernest R Mbega. Status of carotenoids in elite and landrace maize genotypes: Implications for provitamin A biofortification in Tanzania. Food research international (Ottawa, Ont.). 2022 06; 156(?):111303. doi: 10.1016/j.foodres.2022.111303. [PMID: 35651063]
May A Beydoun, Hind A Beydoun, Marie T Fanelli-Kuczmarski, Jordan Weiss, Sharmin Hossain, Jose Atilio Canas, Michele Kim Evans, Alan B Zonderman. Association of Serum Antioxidant Vitamins and Carotenoids With Incident Alzheimer Disease and All-Cause Dementia Among US Adults. Neurology. 2022 05; 98(21):e2150-e2162. doi: 10.1212/wnl.0000000000200289. [PMID: 35508396]
Minu S Thomas, Michael Puglisi, Olga Malysheva, Marie A Caudill, Maria Sholola, Jessica L Cooperstone, Maria Luz Fernandez. Eggs Improve Plasma Biomarkers in Patients with Metabolic Syndrome Following a Plant-Based Diet-A Randomized Crossover Study. Nutrients. 2022 May; 14(10):. doi: 10.3390/nu14102138. [PMID: 35631279]
Xinyao Dai, Huanhuan Yin, Jing Zhang, Fang Tian, Xiaokun Cai, Yingyi Mao, Hanxiao Sun, He Wang, Xiang Li, Hui-Lian Zhu, Lishi Zhang, Jinyao Chen, Yanrong Zhao. Carotenoid Profile in Maternal/Cord Plasma and Changes in Breast Milk along Lactation and Its Association with Dietary Intake: A Longitudinal Study in a Coastal City in Southern China. Nutrients. 2022 May; 14(9):. doi: 10.3390/nu14091989. [PMID: 35565956]
Anil Kumar Patel, Akash Pralhad Vadrale, Yi-Sheng Tseng, Chiu-Wen Chen, Cheng-Di Dong, Reeta Rani Singhania. Bioprospecting of marine microalgae from Kaohsiung Seacoast for lutein and lipid production. Bioresource technology. 2022 May; 351(?):126928. doi: 10.1016/j.biortech.2022.126928. [PMID: 35257880]
Jia-Yi Lin, Sefli Sri Wahyu Effendi, I-Son Ng. Enhanced carbon capture and utilization (CCU) using heterologous carbonic anhydrase in Chlamydomonas reinhardtii for lutein and lipid production. Bioresource technology. 2022 May; 351(?):127009. doi: 10.1016/j.biortech.2022.127009. [PMID: 35304253]
Donatella Carbonera, Alessandro Agostini, Marco Bortolus, Luca Dall'Osto, Roberto Bassi. Violaxanthin and Zeaxanthin May Replace Lutein at the L1 Site of LHCII, Conserving the Interactions with Surrounding Chlorophylls and the Capability of Triplet-Triplet Energy Transfer. International journal of molecular sciences. 2022 Apr; 23(9):. doi: 10.3390/ijms23094812. [PMID: 35563202]
Ramaraj Sathasivam, Nam Su Kim, Minsol Choi, Haejin Kwon, Bao Van Nguyen, Jae Kwang Kim, Dae Hui Jeong, Eung Jun Park, Hong Woo Park, Sang Un Park. Identification, In Silico Characterization, and Differential Expression Profiles of Carotenoid, Xanthophyll, Apocarotenoid Biosynthetic Pathways Genes, and Analysis of Carotenoid and Xanthophyll Accumulation in Heracleum moellendorffii Hance. International journal of molecular sciences. 2022 Apr; 23(9):. doi: 10.3390/ijms23094845. [PMID: 35563233]
Nami Yamano, Peng Wang, Feng-Qin Dong, Jian-Ping Zhang. Lipid-Enhanced Photoprotection of LHCII in Membrane Nanodisc by Reducing Chlorophyll Triplet Production. The journal of physical chemistry. B. 2022 04; 126(14):2669-2676. doi: 10.1021/acs.jpcb.1c10557. [PMID: 35377647]
Daniela Diaz-MacAdoo, Maria Teresa Mata, Carlos Riquelme. Influence of Irradiance and Wavelength on the Antioxidant Activity and Carotenoids Accumulation in Muriellopsis sp. Isolated from the Antofagasta Coastal Desert. Molecules (Basel, Switzerland). 2022 Apr; 27(8):. doi: 10.3390/molecules27082412. [PMID: 35458610]
Fenghui Pan, Wenxia Cui, Lei Gao, Xiaoting Shi, Haiyan Yang, Yun Hu, Man Li. Serum lutein is a promising biomarker for type 2 diabetes mellitus and diabetic kidney disease in the elderly. Journal of clinical laboratory analysis. 2022 Apr; 36(4):e24350. doi: 10.1002/jcla.24350. [PMID: 35293029]
Haiyan Luo, Zhengze Li, Chad R Straight, Qi Wang, Jiazhi Zhou, Yukun Sun, Chia-Yu Lo, Lingxiao Yi, Yanyan Wu, Jingyuan Huang, William Wolfe, Dianne Z Sutherland, Mark S Miller, David Julian McClements, Eric A Decker, Hang Xiao. Black pepper and vegetable oil-based emulsion synergistically enhance carotenoid bioavailability of raw vegetables in humans. Food chemistry. 2022 Mar; 373(Pt B):131277. doi: 10.1016/j.foodchem.2021.131277. [PMID: 34799132]
Hyun Gi Koh, Yong Tae Jeong, Bongsoo Lee, Yong Keun Chang. Light Stress after Heterotrophic Cultivation Enhances Lutein and Biofuel Production from a Novel Algal Strain Scenedesmus obliquus ABC-009. Journal of microbiology and biotechnology. 2022 Mar; 32(3):378-386. doi: 10.4014/jmb.2108.08021. [PMID: 34584038]