trans-Vaccenic acid (BioDeep_00000400559)

Main id: BioDeep_00000009097

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(11E)-octadec-11-enoic acid

化学式: C18H34O2 (282.2558664)
中文名称: 反式-11-十八烯酸, 反式十八烷酸, 反异油酸
谱图信息: 最多检出来源 () 0%

Reviewed

Last reviewed on 2024-10-24.

Cite this Page

trans-Vaccenic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/trans-vaccenic_acid (retrieved 2024-11-05) (BioDeep RN: BioDeep_00000400559). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCCCCC/C=C/CCCCCCCCCC(=O)O
InChI: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-8H,2-6,9-17H2,1H3,(H,19,20)/b8-7+

描述信息

The trans- isomer of vaccenic acid.
trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level.
trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level.

同义名列表

2 个代谢物同义名

trans-11-octadecenoic acid; trans-Vaccenic acid



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

101 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Genlai Dong, Shijie Xu, Shuobo Shi. De Novo Biosynthesis of Free Vaccenic Acid with a Low Content of Oleic Acid in Saccharomyces cerevisiae. Journal of agricultural and food chemistry. 2023 Nov; 71(43):16204-16211. doi: 10.1021/acs.jafc.3c04793. [PMID: 37856078]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • P G Toral, G Hervás, P Frutos. Effect of lipid supplementation on the endogenous synthesis of milk cis-9,trans-11 conjugated linoleic acid in dairy sheep and goats: A tracer assay with 13C-vaccenic acid. Journal of dairy science. 2022 Jan; 105(1):255-268. doi: 10.3168/jds.2021-20728. [PMID: 34763909]
  • Shanjie Wang, Wei Tian, Yige Liu, Guangcan Yan, Shaohong Fang, Yafeng Wang, Bo Yu. Temporal trend of circulating trans-fatty acids and risk of long-term mortality in general population. Clinical nutrition (Edinburgh, Scotland). 2021 03; 40(3):1095-1101. doi: 10.1016/j.clnu.2020.07.010. [PMID: 32768317]
  • N L Weir, B T Steffen, W Guan, L M Johnson, L Djousse, K J Mukamal, M Y Tsai. Circulating omega-7 fatty acids are differentially related to metabolic dysfunction and incident type II diabetes: The Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes & metabolism. 2020 09; 46(4):319-325. doi: 10.1016/j.diabet.2019.10.005. [PMID: 31706030]
  • Ilse G Pranger, Eva Corpeleijn, Frits A J Muskiet, Ido P Kema, Cécile Singh-Povel, Stephan J L Bakker. Circulating fatty acids as biomarkers of dairy fat intake: data from the lifelines biobank and cohort study. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2019 Jun; 24(4):360-372. doi: 10.1080/1354750x.2019.1583770. [PMID: 30773031]
  • Buyun Liu, Yangbo Sun, Guifeng Xu, Yang Du, Avanthi S Ajjarapu, Linda G Snetselaar, Wei Bao. Association between plasma concentrations of elaidic acid, a major trans fatty acid, and depression in a nationally representative sample of U.S. adults. Journal of affective disorders. 2019 Apr; 249(?):301-306. doi: 10.1016/j.jad.2019.02.032. [PMID: 30797122]
  • Farkas Sarnyai, Mária Berinkeiné Donkó, Judit Mátyási, Zsófia Gór-Nagy, Ildikó Marczi, Laura Simon-Szabó, Veronika Zámbó, Anna Somogyi, Tamás Csizmadia, Péter Lőw, Péter Szelényi, Éva Kereszturi, Blanka Tóth, Miklós Csala. Cellular toxicity of dietary trans fatty acids and its correlation with ceramide and diglyceride accumulation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Feb; 124(?):324-335. doi: 10.1016/j.fct.2018.12.022. [PMID: 30572061]
  • Qian Zhang, Yuwei Yang, Mingjun Hu, Haibo Li, Qi Zhong, Fen Huang. Relationship between plasma trans-fatty acid isomer concentrations and self-reported cardiovascular disease risk in US adults. International journal of food sciences and nutrition. 2018 Dec; 69(8):976-984. doi: 10.1080/09637486.2018.1428538. [PMID: 29376474]
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  • Dominika Jamioł-Milc, Ewa Stachowska, Tomasz Janus, Anna Barcz, Dariusz Chlubek. [Trans fatty acids (elaidic and vaccenic) in the human milk]. Pomeranian journal of life sciences. 2015; 61(1):58-63. doi: . [PMID: 27116857]
  • Dominika Jamioł-Milc, Ewa Stachowska, Tomasz Janus, Anna Barcz, Dariusz Chlubek. Elaidic acid and vaccenic acid in the plasma of pregnant women and umbilical blood plasma. Pomeranian journal of life sciences. 2015; 61(1):51-7. doi: 10.21164/pomjlifesci.52. [PMID: 27116856]
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  • M Miriam Jacome-Sosa, Faye Borthwick, Rabban Mangat, Richard Uwiera, Martin J Reaney, Jianheng Shen, Ariel D Quiroga, René L Jacobs, Richard Lehner, Spencer D Proctor, Randal C Nelson. Diets enriched in trans-11 vaccenic acid alleviate ectopic lipid accumulation in a rat model of NAFLD and metabolic syndrome. The Journal of nutritional biochemistry. 2014 Jul; 25(7):692-701. doi: 10.1016/j.jnutbio.2014.02.011. [PMID: 24775093]
  • Roman A Sidorov, Anatoly V Zhukov, Vasily P Pchelkin, Andrei G Vereshchagin, Vladimir D Tsydendambaev. Dynamics of fatty-acid composition of neutral acylglycerols in maturing euonymus fruits. Chemistry & biodiversity. 2014 Apr; 11(4):581-92. doi: 10.1002/cbdv.201300305. [PMID: 24706628]
  • A Ishlak, A A AbuGhazaleh, M Günal. Short communication: Effect of blackberry and pomegranate oils on vaccenic acid formation in a single-flow continuous culture fermentation system. Journal of dairy science. 2014 Feb; 97(2):1067-71. doi: 10.3168/jds.2013-6860. [PMID: 24342694]
  • Vincent Rioux, Frédérique Pédrono, Hélène Blanchard, Cécile Duby, Nathalie Boulier-Monthéan, Laurence Bernard, Erwan Beauchamp, Daniel Catheline, Philippe Legrand. Trans-vaccenate is Δ13-desaturated by FADS3 in rodents. Journal of lipid research. 2013 Dec; 54(12):3438-52. doi: 10.1194/jlr.m042572. [PMID: 24070791]
  • Valentina Vasta, Dorra Aouadi, Daniela M R Brogna, Manuel Scerra, Giuseppe Luciano, Alessandro Priolo, Hichem Ben Salem. Effect of the dietary supplementation of essential oils from rosemary and artemisia on muscle fatty acids and volatile compound profiles in Barbarine lambs. Meat science. 2013 Oct; 95(2):235-41. doi: 10.1016/j.meatsci.2012.12.021. [PMID: 23747617]
  • P Vahmani, A H Fredeen, K E Glover. Effect of supplementation with fish oil or microalgae on fatty acid composition of milk from cows managed in confinement or pasture systems. Journal of dairy science. 2013 Oct; 96(10):6660-70. doi: 10.3168/jds.2013-6914. [PMID: 23958023]
  • M S Herrera-Meza, M R Mendoza-López, O García-Barradas, M G Sanchez-Otero, E R Silva-Hernández, J O Angulo, R M Oliart-Ros. Dietary anhydrous milk fat naturally enriched with conjugated linoleic acid and vaccenic acid modify cardiovascular risk biomarkers in spontaneously hypertensive rats. International journal of food sciences and nutrition. 2013 Aug; 64(5):575-86. doi: 10.3109/09637486.2013.763908. [PMID: 23360131]
  • Suresh K Mohankumar, Danielle Hanke, Linda Siemens, Alexander Cattini, Jennifer Enns, Jianheng Shen, Martin Reaney, Peter Zahradka, Carla G Taylor. Dietary supplementation of trans-11-vaccenic acid reduces adipocyte size but neither aggravates nor attenuates obesity-mediated metabolic abnormalities in fa/fa Zucker rats. The British journal of nutrition. 2013 May; 109(9):1628-36. doi: 10.1017/s000711451200339x. [PMID: 22914200]
  • Arshya Hashim, M Salman Khan, Mohd Sajid Khan, Mohd Hassan Baig, Saheem Ahmad. Antioxidant and α -amylase inhibitory property of phyllanthus virgatus L.: an in vitro and molecular interaction study. BioMed research international. 2013; 2013(?):729393. doi: 10.1155/2013/729393. [PMID: 23957001]
  • Sasmita Tripathy, Donald B Jump. Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice. Journal of lipid research. 2013 Jan; 54(1):71-84. doi: 10.1194/jlr.m028787. [PMID: 23099444]
  • P G Toral, Y Chilliard, L Bernard. Short communication: in vivo deposition of [1-13C]vaccenic acid and the product of its Δ9-desaturation, [1-13C]rumenic acid, in the body tissues of lactating goats fed oils. Journal of dairy science. 2012 Nov; 95(11):6755-9. doi: 10.3168/jds.2012-5620. [PMID: 22959933]
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  • Ye Wang, Maria M Jacome-Sosa, Megan R Ruth, Yan Lu, Jianheng Shen, Martin J Reaney, Shannon L Scott, Michael E R Dugan, Hope D Anderson, Catherine J Field, Spencer D Proctor, Donna F Vine. The intestinal bioavailability of vaccenic acid and activation of peroxisome proliferator-activated receptor-α and -γ in a rodent model of dyslipidemia and the metabolic syndrome. Molecular nutrition & food research. 2012 Aug; 56(8):1234-46. doi: 10.1002/mnfr.201100517. [PMID: 22714958]
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