Folic acid (BioDeep_00000400036)

Main id: BioDeep_00000000725

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


Folic acid ,approx

化学式: C19H19N7O6 (441.1397)
中文名称: 叶酸
谱图信息: 最多检出来源 Homo sapiens(blood) 42.97%

分子结构信息

SMILES: C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N
InChI: InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

描述信息

CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2727; ORIGINAL_PRECURSOR_SCAN_NO 2725
B - Blood and blood forming organs > B03 - Antianemic preparations > B03B - Vitamin b12 and folic acid > B03BB - Folic acid and derivatives
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D006401 - Hematologic Agents > D006397 - Hematinics
D018977 - Micronutrients > D014815 - Vitamins
V - Various > V04 - Diagnostic agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2742; ORIGINAL_PRECURSOR_SCAN_NO 2740
CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2705; ORIGINAL_PRECURSOR_SCAN_NO 2702
CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2726; ORIGINAL_PRECURSOR_SCAN_NO 2724
CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2724; ORIGINAL_PRECURSOR_SCAN_NO 2722
CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2722; ORIGINAL_PRECURSOR_SCAN_NO 2720
CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5826; ORIGINAL_PRECURSOR_SCAN_NO 5821
CONFIDENCE standard compound; INTERNAL_ID 452; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5819; ORIGINAL_PRECURSOR_SCAN_NO 5814
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency[1][2][3][4].
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency[1][2][3][4].

同义名列表

6 个代谢物同义名

Folic acid; Folic acid ,approx; Vitamin B9; Vitamin M; Folate; Folic acid



数据库引用编号

81 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

22 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ACE, AKT1, FBP1, GCH1, MTHFD1, SHMT1, SLC46A1, TYMS
Endosome membrane 2 SLC46A1, TFRC
Endoplasmic reticulum membrane 2 CD4, TKT
Mitochondrion membrane 1 ABCG2
Nucleus 8 AKT1, DNMT1, DNMT3B, FBP1, GCH1, RFC1, SHMT1, TYMS
cytosol 10 AKT1, COMT, FBP1, GCH1, MTHFD1, MTHFR, NAT1, SHMT1, TKT, TYMS
dendrite 1 COMT
mitochondrial membrane 1 ABCG2
nuclear body 1 TKT
nucleoplasm 8 ABCG2, AKT1, DNMT1, DNMT3B, GCH1, RFC1, SHMT1, TKT
Cell membrane 10 ABCG2, ACE, AKT1, CD4, COMT, NAT1, RFC1, SLC46A1, TFRC, TKT
lamellipodium 1 AKT1
Multi-pass membrane protein 4 ABCG2, NAT1, RFC1, SLC46A1
Synapse 2 COMT, NAT1
cell cortex 1 AKT1
cell surface 4 EPO, NAT1, SLC46A1, TFRC
glutamatergic synapse 2 AKT1, TFRC
mitochondrial inner membrane 1 TYMS
postsynapse 1 AKT1
presynaptic membrane 1 NAT1
Lysosome 1 ACE
endosome 3 ACE, SLC46A1, TFRC
plasma membrane 11 ABCG2, ACE, AKT1, CD4, COMT, NAT1, RFC1, SLC46A1, TCN2, TFRC, TKT
synaptic vesicle membrane 1 NAT1
Membrane 8 ABCG2, ACE, AKT1, COMT, MTHFD1, NAT1, SLC46A1, TFRC
apical plasma membrane 5 ABCG2, NAT1, RFC1, SLC46A1, TKT
axon 2 COMT, NAT1
basolateral plasma membrane 4 NAT1, RFC1, SLC46A1, TFRC
extracellular exosome 9 ACE, COMT, EPO, FBP1, MTHFD1, RFC1, SHMT1, TFRC, TKT
extracellular space 4 ACE, EPO, TCN2, TFRC
lysosomal lumen 1 TCN2
perinuclear region of cytoplasm 1 TFRC
mitochondrion 5 DNMT1, GCH1, MTHFD1, SHMT1, TYMS
protein-containing complex 2 AKT1, GCH1
intracellular membrane-bounded organelle 2 COMT, TFRC
pericentric heterochromatin 1 DNMT1
Single-pass type I membrane protein 3 ACE, CD4, TKT
Secreted 3 ACE, EPO, TCN2
extracellular region 4 ACE, EPO, TCN2, TFRC
neuronal cell body membrane 1 NAT1
Mitochondrion matrix 1 TYMS
mitochondrial matrix 1 TYMS
Extracellular side 1 COMT
nuclear membrane 1 GCH1
external side of plasma membrane 4 ACE, CD4, TCN2, TFRC
Extracellular vesicle 1 TFRC
actin cytoskeleton 1 TKT
cytoplasmic vesicle 2 GCH1, TFRC
microtubule cytoskeleton 1 AKT1
Early endosome 2 CD4, TFRC
cell-cell junction 1 AKT1
clathrin-coated pit 1 TFRC
recycling endosome 1 TFRC
Single-pass type II membrane protein 2 COMT, TFRC
vesicle 2 AKT1, TKT
Apical cell membrane 3 ABCG2, RFC1, SLC46A1
Mitochondrion inner membrane 1 TYMS
Membrane raft 2 ABCG2, CD4
focal adhesion 1 TKT
spindle 1 AKT1
Peroxisome 1 TKT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
receptor complex 1 TKT
ciliary basal body 1 AKT1
brush border membrane 4 ABCG2, ACE, RFC1, SLC46A1
blood microparticle 1 TFRC
sperm midpiece 1 ACE
Basolateral cell membrane 3 NAT1, RFC1, SLC46A1
Recycling endosome membrane 1 TFRC
female germ cell nucleus 1 DNMT1
Melanosome 1 TFRC
cell body 1 EPO
replication fork 1 DNMT1
basal plasma membrane 1 ACE
secretory granule lumen 1 EPO
HFE-transferrin receptor complex 1 TFRC
endoplasmic reticulum lumen 1 CD4
clathrin-coated endocytic vesicle membrane 2 CD4, TFRC
external side of apical plasma membrane 1 ABCG2
postsynaptic recycling endosome membrane 1 TFRC
T cell receptor complex 1 CD4
[Transferrin receptor protein 1, serum form]: Secreted 1 TFRC
catalytic complex 1 DNMT3B
neuron projection terminus 1 GCH1
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT
DNA replication factor C complex 1 RFC1
Elg1 RFC-like complex 1 RFC1


文献列表

  • Yifei Lu, Chenqi Xu, Kewei Xie, Bingru Zhao, Minzhou Wang, Cheng Qian, Xuemei Chen, Leyi Gu, Wangshu Wu, Renhua Lu. The relationship between thiamin, folic acid and cognitive function in a rat model of uremia. Renal failure. 2024 Dec; 46(1):2329257. doi: 10.1080/0886022x.2024.2329257. [PMID: 38482596]
  • Yunsong Jiang, Mengzhen Xing, Jinyuan Sun, Xin-An Zeng, Charles Brennan, Jayani Chandrapala, Mahsa Majzoobi, Baoguo Sun. Construction of resveratrol and quercetin nanoparticles based on folic acid targeted Maillard products between Jiuzao glutelin isolate and carboxymethyl chitosan: Improved stability and function. Food chemistry. 2024 Aug; 450(?):139296. doi: 10.1016/j.foodchem.2024.139296. [PMID: 38636381]
  • Li He, Lisheng Peng, Lianan Wang, Xiaoyan Jiang, Xinfeng Sun, Haiwen Li, Tong Lin, Zhulin Wu, Sen Lin. Investigation of folate-modified EGCG-loaded thermosensitive nanospheres inducing immunogenic cell death and damage-associated molecular patterns in hepatocellular carcinoma. Biochemical and biophysical research communications. 2024 Jun; 714(?):149976. doi: 10.1016/j.bbrc.2024.149976. [PMID: 38677007]
  • Shijing Yang, Yaoxing Li, Xiaoman Zheng, Xirui Zheng, Yongshi Lin, Shining Guo, Cui Liu. Effects of folate-chicory acid liposome on macrophage polarization and TLR4/NF-κB signaling pathway in ulcerative colitis mouse. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155415. doi: 10.1016/j.phymed.2024.155415. [PMID: 38503151]
  • Chi-Yen Hung, Hsin-Ju Lee, Zhao-Ting Tsai, Shu-Jung Huang, Hsin-Yi Huang, Hui-Ju Tsai, Tsung-Chieh Yao. Maternal folic acid supplementation during pregnancy in association with childhood overweight or obesity. Obesity (Silver Spring, Md.). 2024 Jun; 32(6):1179-1186. doi: 10.1002/oby.24012. [PMID: 38572577]
  • Federica Fogacci, Carmine Pizzi, Luca Bergamaschi, Valentina Di Micoli, Arrigo F G Cicero. Folic acid and plasma lipids: Interactions and effect of folate supplementation. Current problems in cardiology. 2024 Jun; 49(6):102539. doi: 10.1016/j.cpcardiol.2024.102539. [PMID: 38521293]
  • Min Hong, Juan Wang, Haobin Chen, Jiayu Qi, Qinghong Ji, Xiaoyan Liu, Qiaoli Yue, Lei Li, Shuang Cheng. Synthesis and biological evaluation of folic acid-rotenol conjugate as a potent targeted anticancer prodrug. European journal of pharmacology. 2024 May; 970(?):176482. doi: 10.1016/j.ejphar.2024.176482. [PMID: 38452835]
  • Changhao Fang, Karen Kanemaru, Wildemar S P Carvalho, Krista R Fruehauf, Sunshine Zhang, Prem P Das, Caishuang Xu, Yuping Lu, Nandhakishore Rajagopalan, Marianna Kulka, Darren A Makeiff, Michael J Serpe. Self-assembled poloxamer-legumin/vicilin nanoparticles for the nanoencapsulation and controlled release of folic acid. International journal of biological macromolecules. 2024 May; 268(Pt 2):131646. doi: 10.1016/j.ijbiomac.2024.131646. [PMID: 38636765]
  • Yaqi Zhao, Junyan Shi, Bihong Feng, Shuzhi Yuan, Xiaozhen Yue, Wenlin Shi, Zhicheng Yan, Dongying Xu, Jinhua Zuo, Qing Wang. Multi-omic analysis of the extension of broccoli quality during storage by folic acid. Journal of advanced research. 2024 May; 59(?):65-78. doi: 10.1016/j.jare.2023.07.001. [PMID: 37406731]
  • Luiza Avezum, Yann E Madode, Christian Mestres, Nawel Achir, Charlotte Delpech, Morgane Chapron, Olivier Gibert, Loïc Rajjou, Eric Rondet. New insights into the rapid germination process of lentil and cowpea seeds: High thiamine and folate, and low α-galactoside content. Food chemistry. 2024 May; 439(?):138027. doi: 10.1016/j.foodchem.2023.138027. [PMID: 38029561]
  • Xiaowan Hou, Zhiwei Lu, Taifei Yu, Yuanyuan Zhang, Quansheng Yao, Chunyi Zhang, Yiding Niu, Qiuju Liang. Two maize homologs of mammalian proton-coupled folate transporter, ZmMFS_1-62 and ZmMFS_1-73, are essential to salt and drought tolerance. Plant physiology and biochemistry : PPB. 2024 May; 210(?):108623. doi: 10.1016/j.plaphy.2024.108623. [PMID: 38626656]
  • Yaxi Zhang, Jieqiong Wei, Xiangling Feng, Qian Lin, Jing Deng, Yuehan Yuan, Min Li, Bingfang Zhai, Jihua Chen. Folic acid supplementation prevents high body fat-induced bone loss through TGR5 signaling pathways. Food & function. 2024 Apr; 15(8):4193-4206. doi: 10.1039/d4fo00404c. [PMID: 38506303]
  • Ilham Naeem Abd Ali Al-Fatlawi, Vahid Pouresmaeil, Fatemeh Davoodi-Dehaghani, Aida Pouresmaeil, Ali Akhtari, Masoud Homayouni Tabrizi. Effects of solid lipid nanocarrier containing methyl urolithin A by coating folate-bound chitosan and evaluation of its anti-cancer activity. BMC biotechnology. 2024 Apr; 24(1):18. doi: 10.1186/s12896-024-00845-6. [PMID: 38600497]
  • Jinyun Li, Lu Fang, Miaocui Xi, Anyu Ni, Qiuhui Qian, Zejun Wang, Huili Wang, Jin Yan. Toxic effects of triclosan on hepatic and intestinal lipid accumulation in zebrafish via regulation of m6A-RNA methylation. Aquatic toxicology (Amsterdam, Netherlands). 2024 Apr; 269(?):106884. doi: 10.1016/j.aquatox.2024.106884. [PMID: 38458066]
  • Ursula M Leonard, Clarissa L Leydon, Elena Arranz, Mairead E Kiely. Impact of consuming an environmentally protective diet on micronutrients: a systematic literature review. The American journal of clinical nutrition. 2024 Apr; 119(4):927-948. doi: 10.1016/j.ajcnut.2024.01.014. [PMID: 38569787]
  • Yitong Ling, Shiqi Yuan, Xiaxuan Huang, Shanyuan Tan, Hongtao Cheng, Anding Xu, Jun Lyu. Associations of Folate/Folic Acid Supplementation Alone and in Combination With Other B Vitamins on Dementia Risk and Brain Structure: Evidence From 466 224 UK Biobank Participants. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024 Apr; 79(4):. doi: 10.1093/gerona/glad266. [PMID: 38029284]
  • Zhengquan Yan, Yulian Tang, Zhaoran Zhang, Jing Feng, Junkai Hao, Shuo Sun, Meng Li, Yuguang Song, Wei Dong, Lei Hu. Biocompatible Folic-Acid-Strengthened Ag-Ir Quantum Dot Nanozyme for Cell and Plant Root Imaging of Cysteine/Stress and Multichannel Monitoring of Hg2+ and Dopamine. Analytical chemistry. 2024 Mar; 96(10):4299-4307. doi: 10.1021/acs.analchem.4c00081. [PMID: 38414258]
  • Jinfang Song, Wenqiang Yu, Shuangquan Chen, Jiamin Huang, Chujun Zhou, Hua Liang. Remimazolam attenuates inflammation and kidney fibrosis following folic acid injury. European journal of pharmacology. 2024 Mar; 966(?):176342. doi: 10.1016/j.ejphar.2024.176342. [PMID: 38290569]
  • Daniel Leclerc, Karen E Christensen, Alaina M Reagan, Vafa Keser, Yan Luan, Olga V Malysheva, Brandi Wasek, Teodoro Bottiglieri, Marie A Caudill, Gareth R Howell, Rima Rozen. Folate Deficiency and/or the Genetic Variant Mthfr677C >T Can Drive Hepatic Fibrosis or Steatosis in Mice, in a Sex-Specific Manner. Molecular nutrition & food research. 2024 Mar; 68(5):e2300355. doi: 10.1002/mnfr.202300355. [PMID: 38327171]
  • Manru Xu, Yue Zhu, Jinxin Chen, Jie Li, Jingbo Qin, Yiran Fan, Pan Ren, Huixue Hu, Wenbin Wu. Effects of folic acid supplementation on cognitive impairment: A meta-analysis of randomized controlled trials. Journal of evidence-based medicine. 2024 Mar; 17(1):134-144. doi: 10.1111/jebm.12588. [PMID: 38465839]
  • Naveen Rajana, Padakanti Sandeep Chary, Valamla Bhavana, Rajeshwari Deshmukh, Komalatha Dukka, Anamika Sharma, Neelesh Kumar Mehra. Targeted delivery and apoptosis induction of CDK-4/6 inhibitor loaded folic acid decorated lipid-polymer hybrid nanoparticles in breast cancer cells. International journal of pharmaceutics. 2024 Feb; 651(?):123787. doi: 10.1016/j.ijpharm.2024.123787. [PMID: 38184023]
  • Helena J Bentil, Seth Adu-Afarwuah, Elizabeth L Prado, Charles D Arnold, Paul D Hastings, Amanda E Guyer, Mavis O Mensah, Adom Manu, Xiuping Tan, Ebenezer Adjetey, Benjamin Amponsah, Maku E Demuyakor, Kathryn G Dewey, Brietta M Oaks. Sustained effects of small-quantity lipid-based nutrient supplements provided during the first 1000 days on child growth at 9-11 y in a randomized controlled trial in Ghana. The American journal of clinical nutrition. 2024 Feb; 119(2):425-432. doi: 10.1016/j.ajcnut.2023.10.033. [PMID: 38309829]
  • Denglu Zhang, Shuai Liu, Huihui Jiang, Shuangde Liu, Feng Kong. DIA proteomics analysis reveals the mechanism of folic acid-induced acute kidney injury and the effects of icariin. Chemico-biological interactions. 2024 Jan; 390(?):110878. doi: 10.1016/j.cbi.2024.110878. [PMID: 38272249]
  • Rolland Mutumba, Hannah Pesu, Joseph Mbabazi, Eva Greibe, Ebba Nexo, Mette F Olsen, André Briend, Christian Mølgaard, Kim F Michaelsen, Christian Ritz, Suzanne Filteau, Ezekiel Mupere, Henrik Friis, Benedikte Grenov. Effect of lipid-based nutrient supplements on micronutrient status and hemoglobin among children with stunting: secondary analysis of a randomized, controlled trial in Uganda. The American journal of clinical nutrition. 2024 Jan; ?(?):. doi: 10.1016/j.ajcnut.2024.01.018. [PMID: 38278366]
  • Stephen G Andrews, Anthony M Koehle, Devendra Paudel, Thomas Neuberger, A Catharine Ross, Vishal Singh, Teodoro Bottiglieri, Rita Castro. Diet-Induced Severe Hyperhomocysteinemia Promotes Atherosclerosis Progression and Dysregulates the Plasma Metabolome in Apolipoprotein-E-Deficient Mice. Nutrients. 2024 Jan; 16(3):. doi: 10.3390/nu16030330. [PMID: 38337615]
  • Tanja Sobot, Zorislava Bajic, Ranko Skrbic, Snezana Uletilovic, Nebojsa Mandic-Kovacevic, Tanja Cvjetkovic, Ugljesa Malicevic, Djordje Djukanovic, Milica Gajic Bojic, Sanja Jovicic, Maja Barudzija, Milos P Stojiljkovic, Dragan M Djuric. Effect of folic acid on isoprenaline-induced myocardial injury in rats. Physiology international. 2024 Jan; ?(?):. doi: 10.1556/2060.2023.00291. [PMID: 38261080]
  • Chutikun Kanjanaruch, Kerri A Bochantin, Bethania J Dávila Ruiz, Jessica Syring, Yssi Entzie, Layla King, Pawel P Borowicz, Matthew S Crouse, Joel S Caton, Carl R Dahlen, Alison K Ward, Lawrence P Reynolds. One-carbon metabolite supplementation to nutrient-restricted beef heifers affects placental vascularity during early pregnancy. Journal of animal science. 2024 Jan; 102(?):. doi: 10.1093/jas/skae044. [PMID: 38407272]
  • Meryem Al Fatly, Monique T Mulder, Jeanine Roeters van Lennep, Henk J Blom, Kirsten A C Berk. The effect of diet-induced weight loss on circulating homocysteine levels in people with obesity and type 2 diabetes. Nutrition journal. 2024 Jan; 23(1):2. doi: 10.1186/s12937-023-00908-y. [PMID: 38167024]
  • Guangyi Gao, Wenhang Zhou, Xuan Jiang, Jun Ma. Bovine serum albumin and folic acid-modified aurum nanoparticles loaded with paclitaxel and curcumin enhance radiotherapy sensitization for esophageal cancer. International journal of radiation biology. 2024; 100(3):411-419. doi: 10.1080/09553002.2023.2281524. [PMID: 37934908]
  • Zhaoyun Liu, Xi Wang, Chen Zhang, Kui Lin, Jian Yang, Yi Zhang, Jia Hao, Fei Tian. Folic acid-coupled bovine serum albumin-modified magnetic nanocomposites from quantum-sized Fe3O4 and layered double hydroxide for actively targeted delivery of 5-fluorouracil. International journal of biological macromolecules. 2024 Jan; 256(Pt 1):128385. doi: 10.1016/j.ijbiomac.2023.128385. [PMID: 38000576]
  • Chun Lei, Gangjie Wu, Yan Cui, Hui Xia, Jianbing Chen, Xiaoyao Zhan, Yanlan Lv, Meng Li, Ronghua Zhang, Xiaofeng Zhu. Development and validation of a cognitive dysfunction risk prediction model for the abdominal obesity population. Frontiers in endocrinology. 2024; 15(?):1290286. doi: 10.3389/fendo.2024.1290286. [PMID: 38481441]
  • Mozhdeh Aghabagherzadeh, Ehsan Karimi, Mohsen Zareian. Folic Acid-Conjugated Chitosan-Coated Solid Lipid Nanoparticles: Precision Targeting of Artemisia vulgaris Essential Oils for Anticancer Therapy. Chemistry & biodiversity. 2024 Jan; 21(1):e202300187. doi: 10.1002/cbdv.202300187. [PMID: 38164058]
  • Jeremy Marshall, Ana Vargas, Kirstin Bett. B vitamin quantification in lentil seed tissues using ultra-performance liquid chromatography-selected reaction monitoring mass spectrometry. Food chemistry. 2024 Jan; 430(?):136922. doi: 10.1016/j.foodchem.2023.136922. [PMID: 37517945]
  • Yuanyuan Wang, Ruibo Guo, Ming Zou, Lingling Jiang, Liang Kong, Sen Zhao, Xuan Zhang, Wei Wang, Baoli Xu. Combined ROS Sensitive Folate Receptor Targeted Micellar Formulations of Curcumin Effective Against Rheumatoid Arthritis in Rat Model. International journal of nanomedicine. 2024; 19(?):4217-4234. doi: 10.2147/ijn.s458957. [PMID: 38766660]
  • Yoshihiro Kawada, Eriko Hayashi, Yuya Katsuragi, Aya Imamura-Jinda, Takatsugu Hirokawa, Tamio Mizukami, Makoto Hayashi. Identification of Chemicals That Abrogate Folate-Dependent Inhibition of Starch Accumulation in Non-Photosynthetic Plastids of Arabidopsis. Plant & cell physiology. 2023 Dec; 64(12):1551-1562. doi: 10.1093/pcp/pcad116. [PMID: 37801291]
  • Jibiao He, Ruihuan Ding, Yuping Tao, Zhenyu Zhao, Ranran Yuan, Houqian Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi. Folic acid-modified reverse micelle-lipid nanocapsules overcome intestinal barriers and improve the oral delivery of peptides. Drug delivery. 2023 Dec; 30(1):2181744. doi: 10.1080/10717544.2023.2181744. [PMID: 36855953]
  • Jae-Ik Lee, Sang-Soon Kim, Dong-Hyun Kang. Characteristics of Staphylococcus aureus biofilm matured in tryptic soy broth, low-fat milk, or whole milk samples along with inactivation by 405 nm light combined with folic acid. Food microbiology. 2023 Dec; 116(?):104350. doi: 10.1016/j.fm.2023.104350. [PMID: 37689424]
  • Inés Domínguez-López, Rosa Casas, Gemma Chiva-Blanch, Miguel Ángel Martínez-González, Montserrat Fitó, Emilio Ros, Rosa M Lamuela-Raventós, Ramon Estruch. Serum vitamin B12 concentration is associated with improved memory in older individuals with higher adherence to the Mediterranean diet. Clinical nutrition (Edinburgh, Scotland). 2023 12; 42(12):2562-2568. doi: 10.1016/j.clnu.2023.10.025. [PMID: 37948836]
  • Ming Wu, Hongrui Ping, Kun Wang, Hui Ding, Meng Zhang, Ziqiong Yang, Qian Du. Oral delivery of pectin-chitosan hydrogels entrapping macrophage-targeted curcumin-loaded liposomes for the treatment of ulcerative colitis. International journal of pharmaceutics. 2023 Nov; 647(?):123510. doi: 10.1016/j.ijpharm.2023.123510. [PMID: 37839497]
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