3-Methoxytyramine (BioDeep_00000400002)

Main id: BioDeep_00000001873

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


4-(2-Aminoethyl)-2-methoxyphenol

化学式: C9H13NO2 (167.0946)
中文名称: 3-甲氧基色胺盐酸盐
谱图信息: 最多检出来源 Homo sapiens(blood) 56.35%

分子结构信息

SMILES: COC1=C(C=CC(=C1)CCN)O
InChI: InChI=1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3

描述信息

A monomethoxybenzene that is dopamine in which the hydroxy group at position 3 is replaced by a methoxy group. It is a metabolite of the neurotransmitter dopamine and considered a potential biomarker of pheochromocytomas and paragangliomas.
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
3-Methoxytyramine, a well known extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator.

同义名列表

4 个代谢物同义名

4-(2-Aminoethyl)-2-methoxyphenol; 3-Methoxytyramine; 3-O-methyl Dopamine; 3-Methoxytyramine



数据库引用编号

36 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(5)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

41 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 CASP3, DBH, MT1E, MT3, PGLS, SLC6A3, SNCA, TH
Peripheral membrane protein 2 SDHB, VHL
Endoplasmic reticulum membrane 2 DRD1, TAAR1
Nucleus 9 CASP3, DRD1, FOS, MT1E, MT3, MYCN, SNCA, TH, VHL
cytosol 8 CASP3, COMT, FOS, MT3, PGLS, SNCA, TH, VHL
dendrite 3 COMT, DRD2, TH
mitochondrial membrane 1 SDHB
nucleoplasm 5 CASP3, FOS, MYCN, SDHB, VHL
RNA polymerase II transcription regulator complex 1 FOS
Cell membrane 6 COMT, DRD1, DRD2, SLC6A3, TAAR1, VHL
Cell projection, axon 3 SLC6A3, SNCA, TH
Multi-pass membrane protein 5 DRD1, DRD2, SDHD, SLC6A3, TAAR1
Golgi apparatus membrane 1 DRD2
Synapse 4 COMT, DBH, DRD2, SNCA
cell cortex 1 SNCA
cell surface 1 SLC6A3
glutamatergic synapse 3 CASP3, DRD1, DRD2
Golgi membrane 2 DRD2, INS
growth cone 1 SNCA
mitochondrial inner membrane 2 SDHB, SDHD
neuronal cell body 3 CASP3, SLC6A3, SNCA
postsynapse 1 SNCA
presynaptic membrane 3 DRD1, DRD2, SLC6A3
smooth endoplasmic reticulum 1 TH
synaptic vesicle 2 MT3, TH
Cytoplasmic vesicle, secretory vesicle 1 CHGA
Lysosome 1 SNCA
acrosomal vesicle 1 DRD2
plasma membrane 8 COMT, DRD1, DRD2, SDHB, SLC6A3, SNCA, TAAR1, VHL
synaptic vesicle membrane 2 DRD2, SNCA
terminal bouton 1 TH
Membrane 5 COMT, DBH, MYCN, SLC6A3, SNCA
axon 6 COMT, DRD2, MT3, SLC6A3, SNCA, TH
extracellular exosome 2 COMT, PGLS
endoplasmic reticulum 3 DBH, FOS, VHL
extracellular space 6 CHGA, DBH, IL6, INS, MT3, SNCA
perinuclear region of cytoplasm 4 CHGA, MT3, SNCA, TH
mitochondrion 5 SDHB, SDHD, SNCA, TH, VHL
protein-containing complex 1 SNCA
intracellular membrane-bounded organelle 2 COMT, DBH
postsynaptic density 1 CASP3
Secreted 5 CHGA, DBH, IL6, INS, SNCA
extracellular region 5 CHGA, DBH, IL6, INS, SNCA
cytoplasmic side of plasma membrane 1 TH
mitochondrial outer membrane 1 MT3
astrocyte end-foot 1 MT3
neuronal cell body membrane 1 SLC6A3
mitochondrial matrix 1 SDHB
Extracellular side 1 COMT
centriolar satellite 1 DBH
ciliary membrane 2 DRD1, DRD2
actin cytoskeleton 1 SNCA
dendritic spine 3 DRD1, DRD2, MT3
perikaryon 2 DRD2, TH
cytoplasmic vesicle 1 TH
nucleolus 1 MYCN
Melanosome membrane 1 TH
Single-pass type II membrane protein 2 COMT, DBH
postsynaptic membrane 3 DRD1, DRD2, SLC6A3
Cytoplasm, perinuclear region 1 TH
Mitochondrion inner membrane 2 SDHB, SDHD
Matrix side 1 SDHB
Membrane raft 1 SLC6A3
microtubule 1 MT3
GABA-ergic synapse 2 DRD1, DRD2
flotillin complex 1 SLC6A3
Cell projection, dendritic spine 1 DRD1
secretory granule 1 CHGA
lateral plasma membrane 1 DRD2
Cell projection, neuron projection 1 SLC6A3
neuron projection 2 SLC6A3, TH
cilium 2 DRD1, DRD2
chromatin 2 FOS, MYCN
supramolecular fiber 1 SNCA
non-motile cilium 2 DRD1, DRD2
sperm flagellum 1 DRD2
Endomembrane system 1 TAAR1
endosome lumen 1 INS
Cell projection, dendrite 1 DRD1
[Isoform 1]: Cytoplasm 1 VHL
[Isoform 3]: Cytoplasm 1 VHL
secretory granule lumen 2 DBH, INS
secretory granule membrane 1 DBH
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 IL6, INS
nuclear matrix 1 FOS
axon terminus 3 DRD2, SLC6A3, SNCA
endocytic vesicle 1 DRD2
transport vesicle 2 CHGA, INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
mitochondrial envelope 1 SDHD
respiratory chain complex II (succinate dehydrogenase) 2 SDHB, SDHD
neuronal dense core vesicle 1 CHGA
protein-DNA complex 1 FOS
death-inducing signaling complex 1 CASP3
dopaminergic synapse 2 DRD2, SLC6A3
intracellular non-membrane-bounded organelle 1 VHL
Cytoplasmic vesicle, secretory vesicle membrane 1 DBH
Cell projection, cilium membrane 1 DRD1
ribosome 1 MT3
transcription factor AP-1 complex 1 FOS
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 CHGA
transport vesicle membrane 1 DBH
inclusion body 2 MT3, SNCA
interleukin-6 receptor complex 1 IL6
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
chromaffin granule 1 CHGA
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
[Serpinin]: Secreted 1 CHGA
G protein-coupled receptor complex 2 DRD1, DRD2
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT


文献列表

  • Joanna Kokoszka, Marta Opalinska, Katarzyna Sitarz, Magdalena Kolasa, Monika Szewczyk, Jolanta Bugajska, Joanna Berska, Krystyna Sztefko, Alicja Hubalewska-Dydejczyk. 24-hours urine metanephrines excretion in patients diagnosed with adrenal incidentaloma: impact of commonly used drugs on clinical decision. Polish archives of internal medicine. 2024 Jan; ?(?):. doi: 10.20452/pamw.16646. [PMID: 38164744]
  • Hongyu Zeng, Xiaoqing Zhang, Qianna Zhen, Yifan He, Haoran Wang, Yang Zhu, Qi Sun, Min Ding. Dual-Template Magnetic Molecularly Imprinted Polymer for Simultaneous Determination of Spot Urine Metanephrines and 3-Methoxytyramine for the Diagnosis of Pheochromocytomas and Paragangliomas. Molecules (Basel, Switzerland). 2022 May; 27(11):. doi: 10.3390/molecules27113520. [PMID: 35684457]
  • Madysen Elbourne, Adam Cawley, Shawn Stanley, Christopher Bowen, Shanlin Fu. Intelligence benefit of the 3-methoxytyramine to tyramine ratio in equine urine. Drug testing and analysis. 2022 May; 14(5):936-942. doi: 10.1002/dta.3264. [PMID: 35343638]
  • Songlin Yu, Weiyan Zhou, Jialei Yu, Ming Li, Shenyan Zhang, Xu Jiang, Huanhong Wang, Xiaoli Ma, Yutong Zou, Danchen Wang, Qian Cheng, Shaowei Xie, Wei Luo, Xiuzhi Guo, Ling Qiu. An automated magnetic bead extraction method for measuring plasma metanephrines and 3-methoxytyramine using liquid chromatography tandem mass spectrometry. Analytical and bioanalytical chemistry. 2022 May; 414(11):3541-3549. doi: 10.1007/s00216-022-03984-x. [PMID: 35234981]
  • Susan Richter, Bei Qiu, Mirthe Ghering, Carola Kunath, Georgiana Constantinescu, Charlotte Luths, Christina Pamporaki, Nicole Bechmann, Leah Meuter, Aleksandra Kwapiszewska, Timo Deutschbein, Svenja Nölting, Mirko Peitzsch, Mercedes Robledo, Aleksander Prejbisz, Karel Pacak, Volker Gudziol, Henri J L M Timmers, Graeme Eisenhofer. Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine. Endocrine-related cancer. 2022 03; 29(4):213-224. doi: 10.1530/erc-21-0359. [PMID: 35171114]
  • Lu Liu, Wenchun Xie, Zhijing Song, Tianyu Wang, Xuesong Li, Ying Gao, Yan Li, Junqing Zhang, Xiaohui Guo. Addition of 3-methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy. Clinical endocrinology. 2022 02; 96(2):132-138. doi: 10.1111/cen.14585. [PMID: 34486152]
  • Youhei Obata, Mie Kubota-Sakashita, Takaoki Kasahara, Masafumi Mizuno, Takahiro Nemoto, Tadafumi Kato. Phenethylamine is a substrate of monoamine oxidase B in the paraventricular thalamic nucleus. Scientific reports. 2022 01; 12(1):17. doi: 10.1038/s41598-021-03885-6. [PMID: 34996979]
  • Iedan R N Verly, Yvette A H Matser, René Leen, Rutger Meinsma, Marta Fiocco, Jan Koster, Richard Volckmann, Dilara Savci-Heijink, Giuliana Cangemi, Sebastiano Barco, Linda J Valentijn, Godelieve A M Tytgat, André B P van Kuilenburg. Urinary 3-Methoxytyramine Is a Biomarker for MYC Activity in Patients With Neuroblastoma. JCO precision oncology. 2022 01; 6(?):e2000447. doi: 10.1200/po.20.00447. [PMID: 35085004]
  • Kaijuan Wang, Xiaojing Gao, Wei Zhang, Nian Sun, Lan Xie, Hongying Cong, Yutong Guo, Xiaocui Shi, Zhou Zhou. Study of stability and interference for catecholamines and metanephrines, 3-methoxytyramine: key point of an accurate diagnosis for pheochromocytoma and paraganglioma. Scandinavian journal of clinical and laboratory investigation. 2021 Nov; 81(7):564-572. doi: 10.1080/00365513.2021.1980901. [PMID: 34570657]
  • Mirko Peitzsch, Talia Novos, Denise Kaden, Max Kurlbaum, Antonius E van Herwaarden, Daniel Müller, Jo Adaway, Eric Grouzmann, Brett McWhinney, Kirsten Hoad, Gerald Woollard, Ido Kema, Christopher Boot, Martin Fassnacht, Fred Sweep, Tze P Loh, Andrea R Horvath, Graeme Eisenhofer. Harmonization of LC-MS/MS Measurements of Plasma Free Normetanephrine, Metanephrine, and 3-Methoxytyramine. Clinical chemistry. 2021 08; 67(8):1098-1112. doi: 10.1093/clinchem/hvab060. [PMID: 33993248]
  • Christina Pamporaki, Aleksander Prejbisz, Robert Małecki, Frank Pistrosch, Mirko Peitzsch, Steffen Bishoff, Petra Mueller, Iris Meyer, Doreen Reimann, Katarzyna Hanus, Andrzej Januszewicz, Stefan R Bornstein, Simon Parmentier, Carola Kunath, Jacques W M Lenders, Graeme Eisenhofer, Jens Passauer. Optimized procedures for testing plasma metanephrines in patients on hemodialysis. Scientific reports. 2021 07; 11(1):14706. doi: 10.1038/s41598-021-94104-9. [PMID: 34282182]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Meiling Jian, Honglang Huang, Kecheng Li, Liangmin Chuan, Lin Li, Li Jiang. A 3-min UPLC-MS/MS method for the simultaneous determination of plasma catecholamines and their metabolites: Method verification and diagnostic efficiency. Clinical biochemistry. 2021 Jan; 87(?):67-73. doi: 10.1016/j.clinbiochem.2020.10.009. [PMID: 33096053]
  • Haoran Wang, Xiaoqing Zhang, Qianna Zhen, Wenbi Zou, Hong Chen, Can Luo, Min Ding. Detection of spot urinary free metanephrines and 3-methoxytyramine with internal reference correction for the diagnosis of pheochromocytomas and paragangliomas. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2020 Nov; 1156(?):122306. doi: 10.1016/j.jchromb.2020.122306. [PMID: 32829134]
  • Graeme Eisenhofer, Timo Deutschbein, Georgiana Constantinescu, Katharina Langton, Christina Pamporaki, Bruna Calsina, Maria Monteagudo, Mirko Peitzsch, Stephanie Fliedner, Henri J L M Timmers, Nicole Bechmann, Maria Fankhauser, Svenja Nölting, Felix Beuschlein, Anthony Stell, Martin Fassnacht, Aleksander Prejbisz, Jacques W M Lenders, Mercedes Robledo. Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma. Clinical chemistry and laboratory medicine. 2020 10; 59(2):353-363. doi: 10.1515/cclm-2020-0904. [PMID: 33001846]
  • Jiaxi Yao, Jun Wang, Linlin Wu, Haihua Lu, Zhonghe Wang, Pengfei Yu, Hang Xiao, Rong Gao, Jing Yu. Perinatal exposure to bisphenol A causes a disturbance of neurotransmitter metabolic pathways in female mouse offspring: A focus on the tryptophan and dopamine pathways. Chemosphere. 2020 Sep; 254(?):126715. doi: 10.1016/j.chemosphere.2020.126715. [PMID: 32334245]
  • Emilia Sbardella, Zoe Maunsell, Christine J H May, Michael Tadman, Tim James, Bahram Jafar-Mohammadi, Andrea M Isidori, Ashley B Grossman, Brian Shine. Random 'spot' urinary metanephrines compared with 24-h-urinary and plasma results in phaeochromocytomas and paragangliomas. European journal of endocrinology. 2020 Aug; 183(2):129-139. doi: 10.1530/eje-19-0809. [PMID: 32413848]
  • Martijn van Faassen, Rainer Bischoff, Karin Eijkelenkamp, Wilhelmina H A de Jong, Claude P van der Ley, Ido P Kema. In Matrix Derivatization Combined with LC-MS/MS Results in Ultrasensitive Quantification of Plasma Free Metanephrines and Catecholamines. Analytical chemistry. 2020 07; 92(13):9072-9078. doi: 10.1021/acs.analchem.0c01263. [PMID: 32484659]
  • Kaijuan Wang, Xiaojing Gao, Hongying Cong, Wei Zhang, Xiaocui Shi, Shuming Dai, Zhou Zhou. Stability and reference intervals of spot urinary fractionated metanephrines and methoxytyramine by tandem mass spectrometry as a screening method for pheochromocytoma and paraganglioma. Endocrine. 2020 07; 69(1):188-195. doi: 10.1007/s12020-020-02267-8. [PMID: 32222878]
  • Mirko Peitzsch, Denise Kaden, Christina Pamporaki, Katharina Langton, Georgiana Constantinescu, Catleen Conrad, Stephanie Fliedner, Richard O Sinnott, Aleksander Prejbisz, Roland Därr, Jacques W M Lenders, Michael Bursztyn, Graeme Eisenhofer. Overnight/first-morning urine free metanephrines and methoxytyramine for diagnosis of pheochromocytoma and paraganglioma: is this an option?. European journal of endocrinology. 2020 May; 182(5):499-509. doi: 10.1530/eje-19-1016. [PMID: 32187575]
  • Zebin Lin, Yuancheng Chen, Jiaolun Li, Zhiru Xu, Hao Wang, Junyi Lin, Xing Ye, Ziqin Zhao, Yiwen Shen, Yurong Zhang, Shuiqing Zheng, Yulan Rao. Pharmacokinetics of N-ethylpentylone and its effect on increasing levels of dopamine and serotonin in the nucleus accumbens of conscious rats. Addiction biology. 2020 05; 25(3):e12755. doi: 10.1111/adb.12755. [PMID: 30985062]
  • Mirko Peitzsch, Elizabeth R Butch, Elizabeth Lovorn, Anastasios Mangelis, Wayne L Furman, Victor M Santana, Barbara Hero, Frank Berthold, Barry L Shulkin, Angela Huebner, Graeme Eisenhofer. Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine. Pediatric blood & cancer. 2020 02; 67(2):e28081. doi: 10.1002/pbc.28081. [PMID: 31724812]
  • Songlin Yu, Yicong Yin, Qianqian Li, Jialei Yu, Wenjing Liu, Danchen Wang, Qian Cheng, Shaowei Xie, Xinqi Cheng, Ling Qiu. Validation of an improved liquid chromatography tandem mass spectrometry method for rapid and simultaneous analysis of plasma catecholamine and their metabolites. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 Oct; 1129(?):121805. doi: 10.1016/j.jchromb.2019.121805. [PMID: 31670057]
  • Mirko Peitzsch, Anastasios Mangelis, Graeme Eisenhofer, Angela Huebner. Age-specific pediatric reference intervals for plasma free normetanephrine, metanephrine, 3-methoxytyramine and 3-O-methyldopa: Particular importance for early infancy. Clinica chimica acta; international journal of clinical chemistry. 2019 Jul; 494(?):100-105. doi: 10.1016/j.cca.2019.03.1620. [PMID: 30904545]
  • Haithem Chtioui, Samira M Sadowski, Bettina Winzeler, Oliver Tschopp, Eric Grouzmann, Karim Abid. High concentration of plasma methoxytyramine: dopamine-producing tumour or Parkinson's disease therapy?. Annals of clinical biochemistry. 2019 07; 56(4):466-471. doi: 10.1177/0004563219835263. [PMID: 30974961]
  • Victoria Treasure, Royce P Vincent, David R Taylor. Falsely elevated plasma 3-methoxytyramine in a patient receiving midodrine therapy. Annals of clinical biochemistry. 2019 05; 56(3):415-416. doi: 10.1177/0004563218818199. [PMID: 30813742]
  • Sebastiano Barco, Iedan Verly, Maria Valeria Corrias, Stefania Sorrentino, Massimo Conte, Gino Tripodi, Godelieve Tytgat, André van Kuilenburg, Maria van der Ham, Monique de Sain-van der Velden, Alberto Garaventa, Giuliana Cangemi. Plasma free metanephrines for diagnosis of neuroblastoma patients. Clinical biochemistry. 2019 Apr; 66(?):57-62. doi: 10.1016/j.clinbiochem.2019.02.012. [PMID: 30822416]
  • Lu Sun, Chanxi Zhang, Chen Xue, Chuanxin Liu, Yumei Wang, Lei Chen, Yanping Deng, Jianmei Huang, Haifeng Zhai. Anxiolytic effect of a novel 9,10-dihydrophenanthrene, juncuenin H, is associated with metabolic changes in cortical serotonin/dopamine levels in mice. Fitoterapia. 2019 Apr; 134(?):165-171. doi: 10.1016/j.fitote.2019.02.030. [PMID: 30825572]
  • Graeme Eisenhofer, Mirko Peitzsch, Denise Kaden, Katharina Langton, Anastasios Mangelis, Christina Pamporaki, Jimmy Masjkur, Aikaterini Geroula, Max Kurlbaum, Timo Deutschbein, Felix Beuschlein, Aleksander Prejbisz, Stefan R Bornstein, Jacques W M Lenders. Reference intervals for LC-MS/MS measurements of plasma free, urinary free and urinary acid-hydrolyzed deconjugated normetanephrine, metanephrine and methoxytyramine. Clinica chimica acta; international journal of clinical chemistry. 2019 Mar; 490(?):46-54. doi: 10.1016/j.cca.2018.12.019. [PMID: 30571948]
  • Giuseppe Di Stolfo, Sandra Mastroianno, Angela Maggio, Giovanni De Luca, Domenico R Potenza, Mauro Pellegrino Salvatori, Aldo Russo. Electrical Remodeling of Ventricular Repolarization Abnormality after Treatment in Pheochromocytoma: U Wave Finding in a Retrospective Analysis. BioMed research international. 2019; 2019(?):2605323. doi: 10.1155/2019/2605323. [PMID: 31093497]
  • Graeme Eisenhofer, Aleksander Prejbisz, Mirko Peitzsch, Christina Pamporaki, Jimmy Masjkur, Natalie Rogowski-Lehmann, Katharina Langton, Elena Tsourdi, Mariola Pęczkowska, Stephanie Fliedner, Timo Deutschbein, Felix Megerle, Henri J L M Timmers, Richard Sinnott, Felix Beuschlein, Martin Fassnacht, Andrzej Januszewicz, Jacques W M Lenders. Biochemical Diagnosis of Chromaffin Cell Tumors in Patients at High and Low Risk of Disease: Plasma versus Urinary Free or Deconjugated O-Methylated Catecholamine Metabolites. Clinical chemistry. 2018 11; 64(11):1646-1656. doi: 10.1373/clinchem.2018.291369. [PMID: 30097498]
  • A S Davison, J A Harrold, G Hughes, B P Norman, J Devine, J Usher, A T Hughes, M Khedr, J A Gallagher, A M Milan, Halford J C G, L R Ranganath. Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone. Molecular genetics and metabolism. 2018 09; 125(1-2):135-143. doi: 10.1016/j.ymgme.2018.07.008. [PMID: 30049652]
  • I R N Verly, A B P van Kuilenburg, N G G M Abeling, S M I Goorden, M Fiocco, F M Vaz, M M van Noesel, C M Zwaan, G J L Kaspers, J H M Merks, H N Caron, G A M Tytgat. 3-Methoxytyramine: An independent prognostic biomarker that associates with high-risk disease and poor clinical outcome in neuroblastoma patients. European journal of cancer (Oxford, England : 1990). 2018 02; 90(?):102-110. doi: 10.1016/j.ejca.2017.11.025. [PMID: 29274926]
  • Kirk L Pappan, Adam D Kennedy, Pilar L Magoulas, Neil A Hanchard, Qin Sun, Sarah H Elsea. Clinical Metabolomics to Segregate Aromatic Amino Acid Decarboxylase Deficiency From Drug-Induced Metabolite Elevations. Pediatric neurology. 2017 Oct; 75(?):66-72. doi: 10.1016/j.pediatrneurol.2017.06.014. [PMID: 28823629]
  • Dipti Rao, Mirko Peitzsch, Aleksander Prejbisz, Katarzyna Hanus, Martin Fassnacht, Felix Beuschlein, Christina Brugger, Stephanie Fliedner, Katharina Langton, Christina Pamporaki, Volker Gudziol, Anthony Stell, Andrzej Januszewicz, Henri J L M Timmers, Jacques W M Lenders, Graeme Eisenhofer. Plasma methoxytyramine: clinical utility with metanephrines for diagnosis of pheochromocytoma and paraganglioma. European journal of endocrinology. 2017 Aug; 177(2):103-113. doi: 10.1530/eje-17-0077. [PMID: 28476870]
  • Leo Lam, Gerald A Woollard, Lochie Teague, James S Davidson. Clinical validation of urine 3-methoxytyramine as a biomarker of neuroblastoma and comparison with other catecholamine-related biomarkers. Annals of clinical biochemistry. 2017 Mar; 54(2):264-272. doi: 10.1177/0004563216654723. [PMID: 27235704]
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  • Tania Hervet, Eric Grouzmann, Silke Grabherr, Patrice Mangin, Cristian Palmiere. Determination of urinary catecholamines and metanephrines in cardiac deaths. International journal of legal medicine. 2016 Jul; 130(4):995-1001. doi: 10.1007/s00414-015-1303-2. [PMID: 26690910]
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