Irisfloretin (BioDeep_00000000378)
Secondary id: BioDeep_00000267811
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C20H18O8 (386.1002)
中文名称: 次野鸢尾黄素
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 93.23%
分子结构信息
SMILES: C12OCOC1=C(OC)C1C(=O)C(C3C=C(OC)C(OC)=C(OC)C=3)=COC=1C=2
InChI: InChI=1S/C20H18O8/c1-22-13-5-10(6-14(23-2)18(13)24-3)11-8-26-12-7-15-19(28-9-27-15)20(25-4)16(12)17(11)21/h5-8H,9H2,1-4H3
描述信息
Irisflorentin is a member of 4-methoxyisoflavones.
Irisflorentin is a natural product found in Iris tectorum, Iris leptophylla, and other organisms with data available.
Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity[1].
Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity[1].
同义名列表
9 个代谢物同义名
8H-1,3-Dioxolo(4,5-g)(1)benzopyran-8-one, 9-methoxy-7-(3,4,5-trimethoxyphenyl)-; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo(4,5-g)(1)benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one; 9-Methoxy-7-(3,4,5-trimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromen-8-one; 9-methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one; 5,3,4,5-Tetramethoxy-6,7-methylenedioxyisoflavone; Irisflorentin; Irisfloretin; Irisflorentin
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:81410
- KEGG: C17958
- PubChem: 170569
- Metlin: METLIN47923
- ChEMBL: CHEMBL487216
- LipidMAPS: LMPK12050419
- MeSH: irisflorentin
- ChemIDplus: 0041743731
- chemspider: 149122
- CAS: 41743-73-1
- medchemexpress: HY-N0268
- PMhub: MS000026240
- PubChem: 96024178
- KNApSAcK: C00009490
- NIKKAJI: J16.937D
- KNApSAcK: 81410
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
11 个相关的物种来源信息
- 58944 - Iris domestica:
- 34205 - Iris germanica:
- 995801 - Iris hookeriana: 10.1021/NP50041A033
- 995802 - Iris kemaonensis: 10.1016/S0031-9422(00)84141-2
- 1871461 - Iris leptophylla: 10.21608/BFSA.1993.70202
- 198821 - Iris potaninii: -
- 198821 - Iris potaninii: 10.1248/CPB.50.1367
- 114617 - Iris tectorum: 10.1016/0031-9422(92)80300-4
- 292520 - Iris tingitana: 10.1016/S0031-9422(00)83844-3
- 33090 - Plants: -
- 33090 - 野鸢尾: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Dongjin Noh, Jin Gyu Choi, Young Bae Lee, Young Pyo Jang, Myung Sook Oh. Protective effects of Belamcandae Rhizoma against skin damage by ameliorating ultraviolet-B-induced apoptosis and collagen degradation in keratinocytes.
Environmental toxicology.
2019 Dec; 34(12):1354-1362. doi:
10.1002/tox.22836. [PMID: 31436008] - Yan-Wei Jia, Zhong-Qiu Zeng, Hai-Li Shi, Jian Liang, Yi-Ming Liu, Ya-Xiong Tang, Xun Liao. Characterization of in vitro metabolites of irisflorentin by rat liver microsomes using high-performance liquid chromatography coupled with tandem mass spectrometry.
Biomedical chromatography : BMC.
2016 Sep; 30(9):1363-70. doi:
10.1002/bmc.3692. [PMID: 26840210] - Ru-Huei Fu, Chia-Wen Tsai, Rong-Tzong Tsai, Shih-Ping Liu, Tzu-Min Chan, Yu-Chen Ho, Hsin-Lien Lin, Yue-Mi Chen, Huey-Shan Hung, Shao-Chih Chiu, Chang-Hai Tsai, Yu-Chi Wang, Woei-Cherng Shyu, Shinn-Zong Lin. Irisflorentin modifies properties of mouse bone marrow-derived dendritic cells and reduces the allergic contact hypersensitivity responses.
Cell transplantation.
2015; 24(3):573-88. doi:
10.3727/096368915x687002. [PMID: 25654487] - B Roger, V Jeannot, X Fernandez, S Cerantola, J Chahboun. Characterisation and quantification of flavonoids in Iris germanica L. and Iris pallida Lam. resinoids from Morocco.
Phytochemical analysis : PCA.
2012 Sep; 23(5):450-5. doi:
10.1002/pca.1379. [PMID: 22213588] - Mingchuan Liu, Shengjie Yang, Linhong Jin, Deyu Hu, Zhibing Wu, Song Yang. Chemical constituents of the ethyl acetate extract of Belamcanda chinensis (L.) DC roots and their antitumor activities.
Molecules (Basel, Switzerland).
2012 May; 17(5):6156-69. doi:
10.3390/molecules17056156. [PMID: 22627971] - Wei-dong Zhang, Wan-jun Yang, Xiao-juan Wang, Yi Gu, Rong Wang. Simultaneous determination of tectorigenin, irigenin and irisflorentin in rat plasma and urine by UHPLC-MS/MS: application to pharmacokinetics.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Dec; 879(31):3735-41. doi:
10.1016/j.jchromb.2011.10.022. [PMID: 22071270] - Yuan-Yuan Zhang, Qi Wang, Lian-Wen Qi, Xiao-Ying Qin, Min-Jian Qin. Characterization and determination of the major constituents in Belamcandae Rhizoma by HPLC-DAD-ESI-MS(n).
Journal of pharmaceutical and biomedical analysis.
2011 Sep; 56(2):304-14. doi:
10.1016/j.jpba.2011.05.040. [PMID: 21715119] - Orawan Monthakantirat, Wanchai De-Eknamkul, Kaoru Umehara, Yohko Yoshinaga, Toshio Miyase, Tsutomu Warashina, Hiroshi Noguchi. Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines.
Journal of natural products.
2005 Mar; 68(3):361-4. doi:
10.1021/np040175c. [PMID: 15787436]
