Amygdalin (BioDeep_00000377964)

 

Secondary id: BioDeep_00000000241

natural product PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


(R)-2-phenyl-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)acetonitrile

化学式: C20H27NO11 (457.15840320000007)
中文名称: 苦杏仁苷, 苦杏仁甙, 苦杏仁素, 杏仁素, 扁桃苷
谱图信息: 最多检出来源 Viridiplantae(plant) 0.05%

Reviewed

Last reviewed on 2024-08-20.

Cite this Page

Amygdalin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/amygdalin (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000377964). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)O)O)O)O)O)O
InChI: InChI=1S/C20H27NO11/c21-6-10(9-4-2-1-3-5-9)30-20-18(28)16(26)14(24)12(32-20)8-29-19-17(27)15(25)13(23)11(7-22)31-19/h1-5,10-20,22-28H,7-8H2

描述信息

D000970 - Antineoplastic Agents
(R)-amygdalin is an amygdalin in which the stereocentre on the cyanohydrin function has R-configuration. It has a role as a plant metabolite, an apoptosis inducer and an antineoplastic agent. It is functionally related to a (R)-mandelonitrile.
D-Amygdalin is a natural product found in Prunus spinosa, Gerbera jamesonii, and other organisms with data available.
Amygdalin is a cyanogenic glucoside isolated from almonds and seeds of other plants of the family Rosaceae. Amygdalin is converted by plant emulsin (a combination of a glucosidase and a nitrilase) or hydrochloric acid into benzaldehyde, D-glucose, and hydrocyanic acid. (NCI04)
A cyanogenic glycoside found in the seeds of Rosaceae.
C274 - Antineoplastic Agent > C1931 - Antineoplastic Plant Product > C29724 - Cyanoglycoside Agent
An amygdalin in which the stereocentre on the cyanohydrin function has R-configuration.
C1907 - Drug, Natural Product
Origin: Plant; Formula(Parent): C20H27NO11; Bottle Name:Amygdalin; PRIME Parent Name:Amygdalin; PRIME in-house No.:V0293, Glycosides, Nitriles
Annotation level-1
Neoamygdalin is a natural product found in Prunus virginiana, Prunus serotina, and other organisms with data available.
Amygdalin is a cyanogenic glucoside isolated from almonds and seeds of other plants of the family Rosaceae. Amygdalin is converted by plant emulsin (a combination of a glucosidase and a nitrilase) or hydrochloric acid into benzaldehyde, D-glucose, and hydrocyanic acid. (NCI04)
A cyanogenic glycoside found in the seeds of Rosaceae.
Amygdalin is a plant glucoside isolated from the stones of rosaceous fruits, such as apricots, peaches, almond, cherries, and plums.
Amygdalin is a plant glucoside isolated from the stones of rosaceous fruits, such as apricots, peaches, almond, cherries, and plums.
Neoamygdalin is a compound identified in the different processed bitter almonds. Neoamygdalin has the potential for the research of cough and asthma[1].

同义名列表

52 个代谢物同义名

Amygdalin; [(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy](phenyl)acetonitrile; (R)-2-phenyl-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)acetonitrile; (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyacetonitrile; Benzeneacetonitrile, alpha-((6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-, (R)-; (R)-alpha-((6-O-beta-D-glucopyranosyl-beta-D- glucopyranosyl)oxy)benzeneacetonitrile; (R)-ALPHA-((6-O-BETA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSYL)OXY)BENZENEACETONITR ILE; (2R)-((6-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)(PHENYL)ACETONITRILE; (R)-alpha-((6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy)benzeneacetonitrile; (2R)-((6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)(phenyl)acetonitrile; (2R)-[(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy](phenyl)acetonitrile; Benzeneacetonitrile,a-[(6-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-, (aR)-; D-Mandelonitrile-beta-D-glucosido-6-beta-D-glucoside; 5-17-08-00118 (Beilstein Handbook Reference); (-)-D-mandelonitrile beta-D-gentiobioside; D-(-)-mandelonitrile-beta-D-gentiobioside; D(-)-Mandelonitrile-beta-D-gentiobioside; Mandelonitrile-beta-gentiobioside; Mandelonitrile beta Gentiobioside; Mandelonitrile gentiobioside; XUCIJNAGGSZNQT-JHSLDZJXSA-N; Amygdalin (Vitamin B17); AMYGDALIN [WHO-DD]; AMYGDALIN [HSDB]; (R)-Amygdaloside; (R)-Laenitrile; AMYGDALIN [MI]; (R)-Amygdalin; Amygdaloside; Neoamygdalin; R-Amygdalin; Vitamin B17; D-Amygdalin; SMP1_000103; Laetrile; (2R)-2-phenyl-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxymethyl]-2-tetrahydropyranyl]oxy]acetonitrile; (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-acetonitrile; (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-acetonitrile; (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-ethanenitrile; STOCK1N-52529; CHEBI:17019; 29883-15-6; C08325; (2R)-2-phenyl-2-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyacetonitrile; NCGC00380662-01_C20H27NO11_[(6-O-Hexopyranosylhexopyranosyl)oxy](phenyl)acetonitrile; (S)-2-phenyl-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)acetonitrile; (2S)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyacetonitrile; Benzeneacetonitrile, alpha-[(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-, (alphaS)-; Benzeneacetonitrile, alpha-((6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-, (S)-; (S)-Amylgdalin; L-Amylgdalin; L-AMYGDALIN



数据库引用编号

96 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(2)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

42 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ping Li, Zihan Zhao, Zongshuo Li, Rong Zeng, Weidong Li. Distinguishing features of Prunus humilis, P. japonica, P. pedunculata seeds and their adulterant based on DNA barcoding, morphological characterization, and chemical profiles. Fitoterapia. 2024 Jun; 175(?):105942. doi: 10.1016/j.fitote.2024.105942. [PMID: 38575088]
  • Virgile Neyman, Maude Quicray, Frédéric Francis, Catherine Michaux. Toxicological, biochemical, and in silico investigations of three trehalase inhibitors for new ways to control aphids. Archives of insect biochemistry and physiology. 2024 Apr; 115(4):e22112. doi: 10.1002/arch.22112. [PMID: 38605672]
  • Wen Cui, Huan Zhou, Ya-Zun Liu, Yan Yang, Yi-Zhong Hu, Zhao-Peng Han, Jian-Er Yu, Zheng Xue. Amygdalin Improves Allergic Asthma via the Thymic Stromal Lymphopoietin-dendritic Cell-OX40 Ligand Axis in a Mouse Model. Iranian journal of allergy, asthma, and immunology. 2023 Oct; 22(5):430-439. doi: 10.18502/ijaai.v22i5.13993. [PMID: 38085145]
  • Kensuke Iwasa, Sosuke Yagishita, Nan Yagishita-Kyo, Anzu Yamagishi, Shinji Yamamoto, Kota Yamashina, Chikara Haruta, Masashi Asai, Kei Maruyama, Kuniyoshi Shimizu, Keisuke Yoshikawa. Long term administration of loquat leaves and their major component, ursolic acid, attenuated endogenous amyloid-β burden and memory impairment. Scientific reports. 2023 10; 13(1):16770. doi: 10.1038/s41598-023-44098-3. [PMID: 37798424]
  • Doaa R I Abdel-Gawad, Marwa A Ibrahim, Usama K Moawad, Shaimaa Kamel, Hossny A El-Banna, Ahmed H El-Banna, Walid Hamdy Hassan, Fatma I Abo El-Ela. Effectiveness of natural biomaterials in the protection and healing of experimentally induced gastric mucosa Ulcer in rats. Molecular biology reports. 2023 Sep; ?(?):. doi: 10.1007/s11033-023-08776-9. [PMID: 37741810]
  • Haoyan Jiao, Shuyu Li, Qingfa Tang. Amygdalin epimers exert discrepant anti-pulmonary fibrosis activity via inhibiting TGF-β1/Smad2/3 pathway. Pulmonary pharmacology & therapeutics. 2023 Aug; 81(?):102230. doi: 10.1016/j.pupt.2023.102230. [PMID: 37364767]
  • Shuyan Li, Shiheng Lu, Lei Wang, Shasha Liu, Lei Zhang, Jialun Du, Ziwen Wu, Xiaojing Huang. Effects of amygdalin on ferroptosis and oxidative stress in diabetic retinopathy progression via the NRF2/ARE signaling pathway. Experimental eye research. 2023 Jul; ?(?):109569. doi: 10.1016/j.exer.2023.109569. [PMID: 37422064]
  • Halfane Lehmane, Arnaud N Kohonou, Atchadé Pascal Tchogou, Radiate Ba, Durand Dah-Nouvlessounon, Oscar Didagbé, Haziz Sina, Maximin Senou, Adolphe Adjanohoun, Lamine Baba-Moussa. Antioxidant, Anti-Inflammatory, and Anti-Cancer Properties of Amygdalin Extracted from Three Cassava Varieties Cultivated in Benin. Molecules (Basel, Switzerland). 2023 Jun; 28(11):. doi: 10.3390/molecules28114548. [PMID: 37299029]
  • Decai Zhang, Jianfen Ye, Yu Song, Yingying Wei, Shu Jiang, Yi Chen, Xingfeng Shao. Isomerization and Stabilization of Amygdalin from Peach Kernels. Molecules (Basel, Switzerland). 2023 Jun; 28(11):. doi: 10.3390/molecules28114550. [PMID: 37299025]
  • Yumin Wei, Yanan Li, Shengguang Wang, Zedong Xiang, Xiaoyu Li, Qingquan Wang, Weichao Dong, Peng Gao, Long Dai. Phytochemistry and pharmacology of Armeniacae semen Amarum: A review. Journal of ethnopharmacology. 2023 May; 308(?):116265. doi: 10.1016/j.jep.2023.116265. [PMID: 36806484]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Esra Erikel, Deniz Yüzbaşıoğlu, Fatma Ünal. A study on Amygdalin's Genotoxicological Safety and Modulatory Activity in Human Peripheral Lymphocytes in vitro. Environmental and molecular mutagenesis. 2023 May; ?(?):. doi: 10.1002/em.22543. [PMID: 37161892]
  • Guoqin Zhang, Meiqi Liu, Zicheng Ma, Meng Wang, Lili Sun, Yanan Liu, Xiaoliang Ren. Analysis of Bitter Almonds and Processed Products Based on HPLC-Fingerprints and Chemometry. Chemistry & biodiversity. 2023 Feb; ?(?):e202200989. doi: 10.1002/cbdv.202200989. [PMID: 36747377]
  • Guoqin Zhang, Huanhuan Li, Lili Sun, Yi Liu, Ying Cao, Xiaoliang Ren, Yanan Liu. Study on the Correlation Between the Appearance Traits and Intrinsic Chemical Quality of Bitter Almonds Based on Fingerprint-Chemometrics. Journal of chromatographic science. 2023 Feb; 61(2):110-118. doi: 10.1093/chromsci/bmac026. [PMID: 35396599]
  • Erick V S Motta, Alejandra Gage, Thomas E Smith, Kristin J Blake, Waldan K Kwong, Ian M Riddington, Nancy Moran. Host-microbiome metabolism of a plant toxin in bees. eLife. 2022 12; 11(?):. doi: 10.7554/elife.82595. [PMID: 36472498]
  • Bingying Wang, Taruna Pandey, Yong Long, Sofia E Delgado-Rodriguez, Matthew D Daugherty, Dengke K Ma. Co-opted genes of algal origin protect C. elegans against cyanogenic toxins. Current biology : CB. 2022 11; 32(22):4941-4948.e3. doi: 10.1016/j.cub.2022.09.041. [PMID: 36223775]
  • Valentina Cecarini, Salima Selmi, Massimiliano Cuccioloni, Chunmei Gong, Laura Bonfili, Yadong Zheng, Manuela Cortese, Mauro Angeletti, Soumaya Kilani, Anna Maria Eleuteri. Targeting Proteolysis with Cyanogenic Glycoside Amygdalin Induces Apoptosis in Breast Cancer Cells. Molecules (Basel, Switzerland). 2022 Nov; 27(21):. doi: 10.3390/molecules27217591. [PMID: 36364419]
  • Atanaska Todorova, Teodora Todorova. Apricot kernels' extract and amygdalin alter bleomycin-induced Ty1 retrotransposition, mitotic gene conversion in the trp-5 locus and reverse point mutations in ilv1-92 allele in Saccharomyces cerevisiae. Archives of microbiology. 2022 Aug; 204(9):542. doi: 10.1007/s00203-022-03155-7. [PMID: 35932430]
  • Congcong Zhang, Jiacheng Lin, Chao Zhen, Fang Wang, Xuehua Sun, Xiaoni Kong, Yueqiu Gao. Amygdalin protects against acetaminophen-induced acute liver failure by reducing inflammatory response and inhibiting hepatocyte death. Biochemical and biophysical research communications. 2022 04; 602(?):105-112. doi: 10.1016/j.bbrc.2022.03.011. [PMID: 35259588]
  • Rocío Lajad, Emilia Moreno, Andrés Arenas. Young honeybees show learned preferences after experiencing adulterated pollen. Scientific reports. 2021 12; 11(1):23327. doi: 10.1038/s41598-021-02700-6. [PMID: 34857828]
  • Wanfu Bai, Qing Liu, Hong Chang, Quanli Liu, Chen Gao, Yingchun Bai, Hongbing Zhou, Songli Shi. Metabolomics reveals the renoprotective effect of n-butanol extract and amygdalin extract from Amygdalus mongolica in rats with renal fibrosis. Artificial cells, nanomedicine, and biotechnology. 2021 Dec; 49(1):556-564. doi: 10.1080/21691401.2021.1952212. [PMID: 34278886]
  • Zhun Xiao, Qiang Ji, Ya-Dong Fu, Si-Qi Gao, Yong-Hong Hu, Wei Liu, Gao-Feng Chen, Yong-Ping Mu, Jia-Mei Chen, Ping Liu. Amygdalin Ameliorates Liver Fibrosis through Inhibiting Activation of TGF-β/Smad Signaling. Chinese journal of integrative medicine. 2021 Nov; ?(?):. doi: 10.1007/s11655-021-3304-y. [PMID: 34816365]
  • Davut Aydın, Korhan Özkan, Ali Aydın. The Combination of Amygdalin with Some Anticancer, Antiparasitic, and Antigout Drugs Against MG63, Saos2, SW1353, and FL Cells In Vitro. Journal of medicinal food. 2021 Nov; 24(11):1230-1234. doi: 10.1089/jmf.2020.0143. [PMID: 33733877]
  • Martin Dimitrov, Ivan Iliev, Krum Bardarov, Dimitrina Georgieva, Teodora Todorova. Phytochemical characterization and biological activity of apricot kernels' extract in yeast-cell based tests and hepatocellular and colorectal carcinoma cell lines. Journal of ethnopharmacology. 2021 Oct; 279(?):114333. doi: 10.1016/j.jep.2021.114333. [PMID: 34146630]
  • Ewa Jaszczak-Wilke, Żaneta Polkowska, Marek Koprowski, Krzysztof Owsianik, Alyson E Mitchell, Piotr Bałczewski. Amygdalin: Toxicity, Anticancer Activity and Analytical Procedures for Its Determination in Plant Seeds. Molecules (Basel, Switzerland). 2021 Apr; 26(8):. doi: 10.3390/molecules26082253. [PMID: 33924691]
  • Jiawei Chen, Yongbin Hu, Xin Mou, Huiyang Wang, Zhujuan Xie. Amygdalin alleviates renal injury by suppressing inflammation, oxidative stress and fibrosis in streptozotocin-induced diabetic rats. Life sciences. 2021 Jan; 265(?):118835. doi: 10.1016/j.lfs.2020.118835. [PMID: 33253723]
  • Ruoyu Wang, Dong Zhang, Kewei Sun, Jianping Peng, Wenfang Zhu, Sihan Yin, Dan Tang, Yunan Wu. Amygdalin promotes the activity of T cells to suppress the progression of HBV-related hepatocellular carcinoma via the JAK2/STAT3 signaling pathway. BMC infectious diseases. 2021 Jan; 21(1):56. doi: 10.1186/s12879-020-05713-0. [PMID: 33435880]
  • Ruoyu Wang, Dong Zhang, Dan Tang, Kewei Sun, Jianping Peng, Wenfang Zhu, Sihan Yin, Yunan Wu. Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl4-induced hepatic fibrosis in rats in vivo. International immunopharmacology. 2021 Jan; 90(?):107151. doi: 10.1016/j.intimp.2020.107151. [PMID: 33296784]
  • Marwa Esmat, Amany Ahmed Abdel-Aal, Maisa Ahmed Shalaby, Mennat-Elrahman Ahmed Fahmy, Manal Abdel Magid Badawi, Marwa Adel Elmallawany, Mona Magdy, Adam Ashraf Afife, Iman Raafat Abdel Shafi. Punica granatum and amygdalin extracts plus cobalamin combined with albendazole reduce larval burden and myositis in experimental trichinosis. Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria. 2021; 30(4):e012021. doi: 10.1590/s1984-29612021084. [PMID: 34730610]
  • Samar Hosny, Heba Sahyon, Magdy Youssef, Amr Negm. Prunus Armeniaca L. Seed Extract and Its Amygdalin Containing Fraction Induced Mitochondrial-Mediated Apoptosis and Autophagy in Liver Carcinogenesis. Anti-cancer agents in medicinal chemistry. 2021; 21(5):621-629. doi: 10.2174/1871520620666200608124003. [PMID: 32510292]
  • Tianyang Wang, Song Lin, Hua Li, Ran Liu, Zihan Liu, Huarong Xu, Qing Li, Kaishun Bi. A stepwise integrated multi-system to screen quality markers of Chinese classic prescription Qingzao Jiufei decoction on the treatment of acute lung injury by combining 'network pharmacology-metabolomics-PK/PD modeling'. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Nov; 78(?):153313. doi: 10.1016/j.phymed.2020.153313. [PMID: 32866904]
  • Kolawole I Ayeni, Michael Sulyok, Rudolf Krska, Chibundu N Ezekiel. Fungal and plant metabolites in industrially-processed fruit juices in Nigeria. Food additives & contaminants. Part B, Surveillance. 2020 Sep; 13(3):155-161. doi: 10.1080/19393210.2020.1741691. [PMID: 32207373]
  • Tomoya Tanaka, Keisuke Kimura, Kimiko Kan, Yoshiko Katori, Kumi Michishita, Hisako Nakano, Takeo Sasamoto. Quantification of amygdalin, prunasin, total cyanide and free cyanide in powdered loquat seeds. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2020 Sep; 37(9):1503-1509. doi: 10.1080/19440049.2020.1778186. [PMID: 32618500]
  • Huifen Zhou, Yu He, Jiehong Yang, Haofang Wan, Liqin Wang, Haitong Wan. Transport properties of paeoniflorin and amygdalin across caco-2 cell monolayer model and their modulation of cytochrome p450 metabolism. Pakistan journal of pharmaceutical sciences. 2020 Jul; 33(4):1569-1575. doi: . [PMID: 33583789]
  • Jian-Ting Gong, Li-Ying Zhao, Dong Xu, Yue-Bao Yao, Bin-Qing Liu, Hui-Qin Zou, Yong-Hong Yan. [Change pattern and correlation analysis of macroscopic characteristics, active components and rancidness degrees of Armeniacae Semen Amarum in deterioration process]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2020 Jul; 45(13):3155-3160. doi: 10.19540/j.cnki.cjcmm.20200424.305. [PMID: 32726024]
  • Xiao-Yan He, Li-Juan Wu, Wen-Xiang Wang, Pei-Jun Xie, Yun-Hui Chen, Fei Wang. Amygdalin - A pharmacological and toxicological review. Journal of ethnopharmacology. 2020 May; 254(?):112717. doi: 10.1016/j.jep.2020.112717. [PMID: 32114166]
  • Pengcheng Huang, Yinghong Tang, Chang Li, Huifen Zhou, Li Yu, Haitong Wan, Yu He. Correlation study between the pharmacokinetics of seven main active ingredients of Mahuang decoction and its pharmacodynamics in asthmatic rats. Journal of pharmaceutical and biomedical analysis. 2020 May; 183(?):113144. doi: 10.1016/j.jpba.2020.113144. [PMID: 32070931]
  • Thulfiqar F Mutar, Ehab Tousson, Ezar Hafez, Maha Abo Gazia, Seham B Salem. Ameliorative effects of vitamin B17 on the kidney against Ehrlich ascites carcinoma induced renal toxicity in mice. Environmental toxicology. 2020 Apr; 35(4):528-537. doi: 10.1002/tox.22888. [PMID: 31821727]
  • Fatemeh Aamazadeh, Alireza Ostadrahimi, Yalda Rahbar Saadat, Jaleh Barar. Bitter apricot ethanolic extract induces apoptosis through increasing expression of Bax/Bcl-2 ratio and caspase-3 in PANC-1 pancreatic cancer cells. Molecular biology reports. 2020 Mar; 47(3):1895-1904. doi: 10.1007/s11033-020-05286-w. [PMID: 32026321]
  • Jie Zhou, Jing Hou, Jun Rao, Conghui Zhou, Yunlong Liu, Wenxi Gao. Magnetically Directed Enzyme/Prodrug Prostate Cancer Therapy Based on β-Glucosidase/Amygdalin. International journal of nanomedicine. 2020; 15(?):4639-4657. doi: 10.2147/ijn.s242359. [PMID: 32636623]
  • Yuzhong Zheng, Guizhong Xin, Guowei Gong, Tina Tx Dong, Ping Li, Karl W K Tsim. Evaluation of Anti-Inflammatory Components of Guizhi Fuling Capsule, an Ancient Chinese Herbal Formula, in Human Umbilical Vein Endothelial Cells. Evidence-based complementary and alternative medicine : eCAM. 2020; 2020(?):2029134. doi: 10.1155/2020/2029134. [PMID: 33149750]
  • Jie Wu, Qiao Zhao. Sweeten Almonds: A Single Mutation in the bHLH2 Transcription Factor. Trends in plant science. 2019 11; 24(11):976-978. doi: 10.1016/j.tplants.2019.09.001. [PMID: 31597602]
  • V Kovacova, A Sarocka, R Omelka, M Bauerova, B Grosskopf, G Formicki, A Kolesarova, M Martiniakova. Subacute exposure to amygdalin influences compact bone remodeling of rabbits. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2019 Aug; 70(4):. doi: 10.26402/jpp.2019.4.15. [PMID: 31741461]
  • R Sánchez-Pérez, S Pavan, R Mazzeo, C Moldovan, R Aiese Cigliano, J Del Cueto, F Ricciardi, C Lotti, L Ricciardi, F Dicenta, R L López-Marqués, B Lindberg Møller. Mutation of a bHLH transcription factor allowed almond domestication. Science (New York, N.Y.). 2019 06; 364(6445):1095-1098. doi: 10.1126/science.aav8197. [PMID: 31197015]
  • Jiamin Shi, Qianqian Chen, Meng Xu, Qing Xia, Tiansheng Zheng, Junliang Teng, Ming Li, Lihong Fan. Recent updates and future perspectives about amygdalin as a potential anticancer agent: A review. Cancer medicine. 2019 06; 8(6):3004-3011. doi: 10.1002/cam4.2197. [PMID: 31066207]
  • Jens Mani, Jochen Rutz, Sebastian Maxeiner, Eva Juengel, Dimitra Bon, Frederik Roos, Felix K-H Chun, Roman A Blaheta. Cyanide and lactate levels in patients during chronic oral amygdalin intake followed by intravenous amygdalin administration. Complementary therapies in medicine. 2019 Apr; 43(?):295-299. doi: 10.1016/j.ctim.2019.03.002. [PMID: 30935547]
  • Asghar Arshi, Sayed Mostafa Hosseini, Fataneh Saleh Khaje Hosseini, Zahra Yousefnejad Amiri, Fatemeh Sadat Hosseini, Mahsa Sheikholia Lavasani, Hossein Kerdarian, Maryam Safarpour Dehkordi. The anti-cancer effect of amygdalin on human cancer cell lines. Molecular biology reports. 2019 Apr; 46(2):2059-2066. doi: 10.1007/s11033-019-04656-3. [PMID: 30725348]
  • Huajie Tian, Lin Liu, Zhixiong Li, Wei Liu, Zhaolin Sun, Yongbin Xu, Shunchun Wang, Chungeng Liang, Yamei Hai, Qin Feng, Yu Zhao, Yiyang Hu, Jinghua Peng. Chinese medicine CGA formula ameliorates liver fibrosis induced by carbon tetrachloride involving inhibition of hepatic apoptosis in rats. Journal of ethnopharmacology. 2019 Mar; 232(?):227-235. doi: 10.1016/j.jep.2018.11.027. [PMID: 30471378]
  • Ziyan Wang, Keyong Fang, Guoqiang Wang, Xuewa Guan, Zhiqiang Pang, Yingqiao Guo, Yuze Yuan, Nan Ran, Yue Liu, Fang Wang. Protective effect of amygdalin on epithelial-mesenchymal transformation in experimental chronic obstructive pulmonary disease mice. Phytotherapy research : PTR. 2019 Mar; 33(3):808-817. doi: 10.1002/ptr.6274. [PMID: 30701599]
  • Soo-Wang Hyun, Junghyun Kim, Bongkyun Park, Kyuhyung Jo, Tae Gu Lee, Jin Sook Kim, Chan-Sik Kim. Apricot Kernel Extract and Amygdalin Inhibit Urban Particulate Matter-Induced Keratoconjunctivitis Sicca. Molecules (Basel, Switzerland). 2019 Feb; 24(3):. doi: 10.3390/molecules24030650. [PMID: 30759852]
  • Muayad Mehdi Abboud, Wajdy Al Awaida, Hakam Hasan Alkhateeb, Asia Numan Abu-Ayyad. Antitumor Action of Amygdalin on Human Breast Cancer Cells by Selective Sensitization to Oxidative Stress. Nutrition and cancer. 2019; 71(3):483-490. doi: 10.1080/01635581.2018.1508731. [PMID: 30407870]
  • Tainá Neves Ferreira, Daniela Pita-Pereira, Samara Graciane Costa, Reginaldo Peçanha Brazil, Caroline Silva Moraes, Hector Manuel Díaz-Albiter, Fernando Ariel Genta. Transmission blocking sugar baits for the control of Leishmania development inside sand flies using environmentally friendly beta-glycosides and their aglycones. Parasites & vectors. 2018 Nov; 11(1):614. doi: 10.1186/s13071-018-3122-z. [PMID: 30501613]
  • Cecilie Cetti Hansen, Mette Sørensen, Thiago A M Veiga, Juliane F S Zibrandtsen, Allison M Heskes, Carl Erik Olsen, Berin A Boughton, Birger Lindberg Møller, Elizabeth H J Neilson. Reconfigured Cyanogenic Glucoside Biosynthesis in Eucalyptus cladocalyx Involves a Cytochrome P450 CYP706C55. Plant physiology. 2018 11; 178(3):1081-1095. doi: 10.1104/pp.18.00998. [PMID: 30297456]
  • Sara Thodberg, Jorge Del Cueto, Rosa Mazzeo, Stefano Pavan, Concetta Lotti, Federico Dicenta, Elizabeth H Jakobsen Neilson, Birger Lindberg Møller, Raquel Sánchez-Pérez. Elucidation of the Amygdalin Pathway Reveals the Metabolic Basis of Bitter and Sweet Almonds (Prunus dulcis). Plant physiology. 2018 11; 178(3):1096-1111. doi: 10.1104/pp.18.00922. [PMID: 30297455]
  • Yezhe Cheng, Yanjie Chu, Xitong Su, Kexia Zhang, Yu Zhang, Zhenzhong Wang, Wei Xiao, Longshan Zhao, Xiaohui Chen. Pharmacokinetic-pharmacodynamic modeling to study the anti-dysmenorrhea effect of Guizhi Fuling capsule on primary dysmenorrhea rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2018 Sep; 48(?):141-151. doi: 10.1016/j.phymed.2018.04.041. [PMID: 30195872]
  • Yu-Tian Zhang, Mei-Feng Xiao, Qiong Liao, Wen-Long Liu, Kai-Wen Deng, Yi-Qun Zhou, Yu Tang, Fu-Yuan He, Yan-Tao Yang. Application of TQSM polypharmacokinetics and its similarity approach to ascertain Q-marker by analyses of transitivity in vivo of five candidates in Buyanghuanwu injection. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2018 Jun; 45(?):18-25. doi: 10.1016/j.phymed.2018.03.012. [PMID: 29555366]
  • Yu-Tian Zhang, Mei-Feng Xiao, Kai-Wen Deng, Yan-Tao Yang, Yi-Qun Zhou, Jin Zhou, Fu-Yuan He, Wen-Long Liu. Novel mathematic models for quantitative transitivity of quality-markers in extraction process of the Buyanghuanwu decoction. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2018 Jun; 45(?):68-75. doi: 10.1016/j.phymed.2018.04.002. [PMID: 29699843]
  • Xiangqun Zhang, Jiangong Hu, Yuzhen Zhuo, Lihua Cui, Caixia Li, Naiqiang Cui, Shukun Zhang. Amygdalin improves microcirculatory disturbance and attenuates pancreatic fibrosis by regulating the expression of endothelin-1 and calcitonin gene-related peptide in rats. Journal of the Chinese Medical Association : JCMA. 2018 May; 81(5):437-443. doi: 10.1016/j.jcma.2017.09.005. [PMID: 29129515]
  • Jorge Del Cueto, Birger Lindberg Møller, Federico Dicenta, Raquel Sánchez-Pérez. β-Glucosidase activity in almond seeds. Plant physiology and biochemistry : PPB. 2018 May; 126(?):163-172. doi: 10.1016/j.plaphy.2017.12.028. [PMID: 29524803]
  • Pedro Diaz-Vivancos, Agustina Bernal-Vicente, Daniel Cantabella, Cesar Petri, José Antonio Hernández. Metabolomics and Biochemical Approaches Link Salicylic Acid Biosynthesis to Cyanogenesis in Peach Plants. Plant & cell physiology. 2017 Dec; 58(12):2057-2066. doi: 10.1093/pcp/pcx135. [PMID: 29036663]
  • Jianzhen Lv, Wen Xiong, Tiantian Lei, Hailian Wang, Minghan Sun, Erwei Hao, Zhiping Wang, Xiaoqi Huang, Shaoping Deng, Jiagang Deng, Yi Wang. Amygdalin ameliorates the progression of atherosclerosis in LDL receptor‑deficient mice. Molecular medicine reports. 2017 Dec; 16(6):8171-8179. doi: 10.3892/mmr.2017.7609. [PMID: 28983592]
  • Paulina M Opyd, Adam Jurgoński, Jerzy Juśkiewicz, Joanna Milala, Zenon Zduńczyk, Bogusław Król. Nutritional and Health-Related Effects of a Diet Containing Apple Seed Meal in Rats: The Case of Amygdalin. Nutrients. 2017 Oct; 9(10):. doi: 10.3390/nu9101091. [PMID: 28974035]
  • Shuya Xu, Xinfang Xu, Shaoxiong Yuan, Huan Liu, Mengnan Liu, Ying Zhang, Hui Zhang, Yan Gao, Ruichao Lin, Xiangri Li. Identification and Analysis of Amygdalin, Neoamygdalin and Amygdalin Amide in Different Processed Bitter Almonds by HPLC-ESI-MS/MS and HPLC-DAD. Molecules (Basel, Switzerland). 2017 Aug; 22(9):. doi: 10.3390/molecules22091425. [PMID: 28867779]
  • Khu S Li, Abbas Ali, Ida I Muhammad. The influence of microwave cooking on the nutritional composition and antioxidant activity of the underutilized perah seed. Acta scientiarum polonorum. Technologia alimentaria. 2017 Jul; 16(3):283-292. doi: 10.17306/j.afs.0497. [PMID: 29055976]
  • Yinghong Tang, Mengkai Zheng, Yu-Lin Chen, Jianzhen Chen, Yu He. Pharmacokinetic Effects of Cinnamic Acid, Amygdalin, Glycyrrhizic Acid and Liquiritin on Ephedra Alkaloids in Rats. European journal of drug metabolism and pharmacokinetics. 2017 Jun; 42(3):527-535. doi: 10.1007/s13318-016-0368-8. [PMID: 27514823]
  • Chao Liu, Xia Li, Honggai Yang, Xinhui Mao, Juan Wang, Wenyuan Gao. Effect of Natural β-Glucosidase Inhibitors in Reducing Toxicity of Amygdalin in Persicae Semen. Phytotherapy research : PTR. 2017 May; 31(5):771-777. doi: 10.1002/ptr.5798. [PMID: 28393463]
  • Youn Young Shim, Clara M Olivia, Jun Liu, Rineke Boonen, Jianheng Shen, Martin J T Reaney. Secoisolariciresinol Diglucoside and Cyanogenic Glycosides in Gluten-free Bread Fortified with Flaxseed Meal. Journal of agricultural and food chemistry. 2016 Dec; 64(50):9551-9558. doi: 10.1021/acs.jafc.6b03962. [PMID: 27998066]
  • Nguyen Phuong Thao, Bui Thi Thuy Luyen, Le Ba Vinh, Jung Yun Lee, Young In Kwon, Young Ho Kim. Rat intestinal sucrase inhibited by minor constituents from the leaves and twigs of Archidendron clypearia (Jack.) Nielsen. Bioorganic & medicinal chemistry letters. 2016 09; 26(17):4272-6. doi: 10.1016/j.bmcl.2016.07.044. [PMID: 27481560]
  • Yun-Xi Zhong, Xiao-Liang Jin, Shi-Yin Gu, Ying Peng, Ke-Rong Zhang, Bing-Chen Ou-Yang, Yu Wang, Wei Xiao, Zhen-Zhong Wang, Ji-Ye Aa, Guang-Ji Wang, Jian-Guo Sun. Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers. Scientific reports. 2016 08; 6(?):31364. doi: 10.1038/srep31364. [PMID: 27527657]
  • Xue-Mei Li, Jing-Hua Peng, Zhao-Lin Sun, Hua-Jie Tian, Xiao-Hua Duan, Lin Liu, Xin Ma, Qin Feng, Ping Liu, Yi-Yang Hu. Chinese medicine CGA formula ameliorates DMN-induced liver fibrosis in rats via inhibiting MMP2/9, TIMP1/2 and the TGF-β/Smad signaling pathways. Acta pharmacologica Sinica. 2016 Jun; 37(6):783-93. doi: 10.1038/aps.2016.35. [PMID: 27133300]
  • Carlos A Mora, Jonas G Halter, Cornel Adler, Andreas Hund, Heidrun Anders, Kang Yu, Wendelin J Stark. Application of the Prunus spp. Cyanide Seed Defense System onto Wheat: Reduced Insect Feeding and Field Growth Tests. Journal of agricultural and food chemistry. 2016 May; 64(18):3501-7. doi: 10.1021/acs.jafc.6b00438. [PMID: 27119432]
  • Roman A Blaheta, Karen Nelson, Axel Haferkamp, Eva Juengel. Amygdalin, quackery or cure?. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2016 Apr; 23(4):367-76. doi: 10.1016/j.phymed.2016.02.004. [PMID: 27002407]
  • Hui Kong, Huihua Qu, Baoping Qu, Wenhao Zeng, Yan Zhao, Xueqian Wang, Qingguo Wang. Correlation between the transdermal characteristics of pseudoephedrine and amygdalin in majiepingchuan in vitro. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2016 Apr; 36(2):238-42. doi: 10.1016/s0254-6272(16)30033-4. [PMID: 27400480]
  • Eva Juengel, Masud Afschar, Jasmina Makarević, Jochen Rutz, Igor Tsaur, Jens Mani, Karen Nelson, Axel Haferkamp, Roman A Blaheta. Amygdalin blocks the in vitro adhesion and invasion of renal cell carcinoma cells by an integrin-dependent mechanism. International journal of molecular medicine. 2016 Mar; 37(3):843-50. doi: 10.3892/ijmm.2016.2454. [PMID: 26781971]
  • V A Yamshanov, E G Kovan'ko, Yu I Pustovalov. Effects of Amygdaline from Apricot Kernel on Transplanted Tumors in Mice. Bulletin of experimental biology and medicine. 2016 Mar; 160(5):712-4. doi: 10.1007/s10517-016-3257-x. [PMID: 27021084]
  • Shuai Song, Qinhai Ma, Qingfa Tang, Feilong Chen, Xuefeng Xing, Yang Guo, Shenshen Guo, Xiaomei Tan, Jiabo Luo. Stereoselective metabolism of amygdalin-based study of detoxification of Semen Armeniacae Amarum in the Herba Ephedrae-Semen Armeniacae Amarum herb pair. Journal of ethnopharmacology. 2016 Feb; 179(?):356-66. doi: 10.1016/j.jep.2015.12.019. [PMID: 26719286]
  • Xiaobing Li, Fuguo Shi, Run Zhang, Chenglong Sun, Chuting Gong, Lingyan Jian, Li Ding. Pharmacokinetics, Safety, and Tolerability of Amygdalin and Paeoniflorin After Single and Multiple Intravenous Infusions of Huoxue-Tongluo Lyophilized Powder for Injection in Healthy Chinese Volunteers. Clinical therapeutics. 2016 Feb; 38(2):327-37. doi: 10.1016/j.clinthera.2015.12.005. [PMID: 26749220]
  • M Farooq Wahab, Zachary S Breitbach, Daniel W Armstrong, Rick Strattan, Alain Berthod. Problems and Pitfalls in the Analysis of Amygdalin and Its Epimer. Journal of agricultural and food chemistry. 2015 Oct; 63(40):8966-73. doi: 10.1021/acs.jafc.5b03120. [PMID: 26431391]
  • Tao Yang, Shan Liu, Chang-Hong Wang, Yan-Yan Tao, Hua Zhou, Cheng-Hai Liu. Comparative pharmacokinetic and tissue distribution profiles of four major bioactive components in normal and hepatic fibrosis rats after oral administration of Fuzheng Huayu recipe. Journal of pharmaceutical and biomedical analysis. 2015 Oct; 114(?):152-8. doi: 10.1016/j.jpba.2015.05.014. [PMID: 26048667]
  • Qing-Yun Yang, Li Song, Ji-Fa Zhang, Zhu-Fang Shen, Quan Liu, Shuai-Nan Liu, Wen-Sheng Zheng, Chun-Suo Yao. Cyanogenetic glycosides and simple glycosides from the linseed meal. Fitoterapia. 2015 Oct; 106(?):78-83. doi: 10.1016/j.fitote.2015.08.008. [PMID: 26307006]
  • Xiao-bing Li, Fu-guo Shi, Ling-yan Jian, Li Ding. [An LC-MS/MS method for the simultaneous determination of amygdalin and paeoniflorin in human urine and application to urinary excretion study]. Yao xue xue bao = Acta pharmaceutica Sinica. 2015 Oct; 50(10):1330-5. doi: . [PMID: 26837182]
  • Krista M Lessner, M Denise Dearing, Ido Izhaki, Michal Samuni-Blank, Zeev Arad, William H Karasov. Small intestinal hydrolysis of plant glucosides: higher glucohydrolase activities in rodents than passerine birds. The Journal of experimental biology. 2015 Sep; 218(Pt 17):2666-9. doi: 10.1242/jeb.121970. [PMID: 26113142]
  • Islamiyat Folashade Bolarinwa. Synthesis and Characterization of Hapten-Protein Conjugates for Antibody Production against Cyanogenic Glycosides. Journal of food protection. 2015 Jul; 78(7):1408-13. doi: 10.4315/0362-028x.jfp-15-033. [PMID: 26197297]
  • Shuai Song, Feilong Chen, Xuefeng Xing, Mengyue Ren, Qinhai Ma, Ying Xie, Qingfa Tang, Jiabo Luo. Concurrent quantification and comparative pharmacokinetic analysis of bioactive compounds in the Herba Ephedrae-Semen Armeniacae Amarum herb pair. Journal of pharmaceutical and biomedical analysis. 2015 May; 109(?):67-73. doi: 10.1016/j.jpba.2015.02.004. [PMID: 25766850]
  • Zygmunt Zdrojewicz, Anna Otlewska, Paweł Hackemer, Agnieszka Otlewska. [Amygdalin - structure and clinical significance]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. 2015 May; 38(227):300-3. doi: . [PMID: 26039028]
  • Harald Sauer, Caroline Wollny, Isabel Oster, Erol Tutdibi, Ludwig Gortner, Sven Gottschling, Sascha Meyer. Severe cyanide poisoning from an alternative medicine treatment with amygdalin and apricot kernels in a 4-year-old child. Wiener medizinische Wochenschrift (1946). 2015 May; 165(9-10):185-8. doi: 10.1007/s10354-014-0340-7. [PMID: 25605411]
  • Islamiyat F Bolarinwa, Caroline Orfila, Michael R A Morgan. Determination of amygdalin in apple seeds, fresh apples and processed apple juices. Food chemistry. 2015 Mar; 170(?):437-42. doi: 10.1016/j.foodchem.2014.08.083. [PMID: 25306368]
  • Tianhua Yan, Qiang Fu, Jing Wang, Shiping Ma. UPLC-MS/MS determination of ephedrine, methylephedrine, amygdalin and glycyrrhizic acid in Beagle plasma and its application to a pharmacokinetic study after oral administration of Ma Huang Tang. Drug testing and analysis. 2015 Feb; 7(2):158-63. doi: 10.1002/dta.1635. [PMID: 24824649]
  • Tao Wang, Shengmin Lu, Qile Xia, Zhongxiang Fang, Stuart Johnson. Separation and purification of amygdalin from thinned bayberry kernels by macroporous adsorption resins. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Jan; 975(?):52-8. doi: 10.1016/j.jchromb.2014.10.038. [PMID: 25438243]
  • Ann M Bode, Zigang Dong. Toxic phytochemicals and their potential risks for human cancer. Cancer prevention research (Philadelphia, Pa.). 2015 Jan; 8(1):1-8. doi: 10.1158/1940-6207.capr-14-0160. [PMID: 25348854]
  • Islamiyat F Bolarinwa, Caroline Orfila, Michael R A Morgan. Development and application of an enzyme-linked immunosorbent assay (ELISA) for the quantification of amygdalin, a cyanogenic glycoside, in food. Journal of agricultural and food chemistry. 2014 Jul; 62(27):6299-305. doi: 10.1021/jf501978d. [PMID: 24905893]
  • Xiao-bo Li, Chang-hui Liu, Rong Zhang, Xiao-tao Huang, Ying-yi Li, Liang Han, Mei-li Xu, Sui-qing Mi, Ning-sheng Wang. Determination and pharmacokinetics of amygdalin in rats by LC-MS-MS. Journal of chromatographic science. 2014 Jul; 52(6):476-81. doi: 10.1093/chromsci/bmt063. [PMID: 23735239]
  • Meng Gao, Yuesheng Wang, Huizhen Wei, Hui Ouyang, Mingzhen He, Lianqing Zeng, Fengyun Shen, Qiang Guo, Yi Rao. [Qualitative and quantitative analysis of amygdalin and its metabolite prunasin in plasma by ultra-high performance liquid chromatography-tandem quadrupole time of flight mass spectrometry and ultra-high performance liquid chromatography-tandem triple quadrupole mass spectrometry]. Se pu = Chinese journal of chromatography. 2014 Jun; 32(6):591-9. doi: 10.3724/sp.j.1123.2014.01021. [PMID: 25269256]
  • Erin Jo Tiedeken, Jane C Stout, Philip C Stevenson, Geraldine A Wright. Bumblebees are not deterred by ecologically relevant concentrations of nectar toxins. The Journal of experimental biology. 2014 May; 217(Pt 9):1620-5. doi: 10.1242/jeb.097543. [PMID: 24526720]
  • Xiaobing Li, Fuguo Shi, Pan Gu, Lingye Liu, Hua He, Li Ding. A sensitive LC-MS/MS method for simultaneous determination of amygdalin and paeoniflorin in human plasma and its application. Journal of pharmaceutical and biomedical analysis. 2014 Apr; 92(?):160-4. doi: 10.1016/j.jpba.2014.01.020. [PMID: 24525563]
  • Lúcia P Santos Pimenta, Menno Schilthuizen, Robert Verpoorte, Young Hae Choi. Quantitative analysis of amygdalin and prunasin in Prunus serotina Ehrh. using (1) H-NMR spectroscopy. Phytochemical analysis : PCA. 2014 Mar; 25(2):122-6. doi: 10.1002/pca.2476. [PMID: 24115144]
  • Rie Tanaka, Akane Nitta, Akito Nagatsu. Application of a quantitative 1H-NMR method for the determination of amygdalin in Persicae semen, Armeniacae semen, and Mume fructus. Journal of natural medicines. 2014 Jan; 68(1):225-30. doi: 10.1007/s11418-013-0783-y. [PMID: 23744252]
  • Islamiyat F Bolarinwa, Caroline Orfila, Michael R A Morgan. Amygdalin content of seeds, kernels and food products commercially-available in the UK. Food chemistry. 2014; 152(?):133-9. doi: 10.1016/j.foodchem.2013.11.002. [PMID: 24444917]
  • Chuanbin Yang, Jia Zhao, Yuanyuan Cheng, Xuechen Li, Jianhui Rong. Bioactivity-guided fractionation identifies amygdalin as a potent neurotrophic agent from herbal medicine Semen Persicae extract. BioMed research international. 2014; 2014(?):306857. doi: 10.1155/2014/306857. [PMID: 25050339]