5,7-Dihydroxy-4H-1-benzopyran-4-one (BioDeep_00000000036)

 

Secondary id: BioDeep_00000864484

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


4H-1-Benzopyran-4-one, 5,7-dihydroxy-

化学式: C9H6O4 (178.0266076)
中文名称: 5,7-二羟基色原酮, 5,7-二羟基色酮
谱图信息: 最多检出来源 Viridiplantae(otcml) 1.12%

分子结构信息

SMILES: c1(cc(c2c(c1)occc2=O)O)O
InChI: InChI=1S/C9H6O4/c10-5-3-7(12)9-6(11)1-2-13-8(9)4-5/h1-4,10,12H

描述信息

5,7-Dihydroxychromone is a member of chromones.
5,7-Dihydroxychromone is a natural product found in Calluna vulgaris, Leucosidea sericea, and other organisms with data available.
5,7-Dihydroxy-4H-1-benzopyran-4-one is found in nuts. 5,7-Dihydroxy-4H-1-benzopyran-4-one is isolated from peanut shells.
Isolated from peanut shells. 5,7-Dihydroxy-4H-1-benzopyran-4-one is found in peanut and nuts.
5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].
5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].

同义名列表

7 个代谢物同义名

4H-1-Benzopyran-4-one, 5,7-dihydroxy-; 5,7-Dihydroxy-4H-1-benzopyran-4-one; 5,7-Dihydroxy-4H-chromen-4-one; 5,7-dihydroxychromen-4-one; 5,7-Dihydroxy-4-chromone; 5,7-Dihydroxychromone; B7S



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

26 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jaeyoung Kwon, Nguyen Tuan Hiep, Dong-Woo Kim, Sungeun Hong, Yuanqiang Guo, Bang Yeon Hwang, Hak Ju Lee, Woongchon Mar, Dongho Lee. Chemical Constituents Isolated from the Root Bark of Cudrania tricuspidata and Their Potential Neuroprotective Effects. Journal of natural products. 2016 08; 79(8):1938-51. doi: 10.1021/acs.jnatprod.6b00204. [PMID: 27420919]
  • Yang Hee Jo, Seon Beom Kim, Qing Liu, Jin Woo Lee, Bang Yeon Hwang, Mi Kyeong Lee. Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activity. Bioorganic & medicinal chemistry letters. 2015 Sep; 25(17):3455-7. doi: 10.1016/j.bmcl.2015.07.017. [PMID: 26227773]
  • Yingzhan Tang, Junhong Ling, Peng Zhang, Xiangrong Zhang, Na Zhang, Wenli Wang, Jiayuan Li, Ning Li. Potential therapeutic agents for circulatory diseases from Bauhinia glauca Benth.subsp. pernervosa. (Da Ye Guan Men). Bioorganic & medicinal chemistry letters. 2015 Aug; 25(16):3217-20. doi: 10.1016/j.bmcl.2015.05.089. [PMID: 26096681]
  • Jiying Qiu, Leilei Chen, Qingjun Zhu, Daijie Wang, Wenliang Wang, Xin Sun, Xiaoyong Liu, Fangling Du. Screening natural antioxidants in peanut shell using DPPH-HPLC-DAD-TOF/MS methods. Food chemistry. 2012 Dec; 135(4):2366-71. doi: 10.1016/j.foodchem.2012.07.042. [PMID: 22980814]
  • Mario Caruana, Johanna Neuner, Tobias Högen, Felix Schmidt, Frits Kamp, Charles Scerri, Armin Giese, Neville Vassallo. Polyphenolic compounds are novel protective agents against lipid membrane damage by α-synuclein aggregates in vitro. Biochimica et biophysica acta. 2012 Nov; 1818(11):2502-10. doi: 10.1016/j.bbamem.2012.05.019. [PMID: 22634381]
  • Jing Li, Dequan Yu. [Chemical constituents from herbs of Erigeron breviscapus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Jun; 36(11):1458-62. doi: . [PMID: 22779177]
  • Yuzhen Guan, Zhiqi Yin, Lian Guo, Xiaojun Huang, Wencai Ye, Wenbin Shen. [Studies on chemical constituents from stems of Cudrania tricuspidata]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 May; 34(9):1108-10. doi: . [PMID: 19685745]
  • Dong-Mei Ren, Zhi Qu, Xiao-Ning Wang, Jing Shi, Hong-Xiang Lou. Simultaneous determination of nine major active compounds in Dracocephalum rupestre by HPLC. Journal of pharmaceutical and biomedical analysis. 2008 Dec; 48(5):1441-5. doi: 10.1016/j.jpba.2008.09.013. [PMID: 18930620]
  • Zhi-Yun Yang, Shi-Hui Qian, Min-Jian Qin. A new triterpenoid saponin from the fruits of Polygonum orientale. Yao xue xue bao = Acta pharmaceutica Sinica. 2008 Apr; 43(4):388-91. doi: ". [PMID: 18664201]
  • Hai-Yan Zhu, Zheng-Wen Yu, Xiao-Sheng Yang, Xiao-Jiang Hao. [Chemical constituents from Viscum nudum and their accelerating PC12 cell differentiation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Aug; 31(16):1340-2. doi: ". [PMID: 17061556]
  • Y Yang. [Studies on the chemical constituents of Viscum liquidambaricolum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 1998 Jan; 21(1):22-3. doi: ". [PMID: 12567965]
  • X Tang, C Yuan, Z Zhang, M Zhou. [Chemical constituents of Bauhinia hupehara Craib]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1992 Oct; 17(10):613-5, 640. doi: ". [PMID: 1294179]