Classification Term: 209

Chromones (ontology term: CHEMONTID:0000144)

Compounds containing a benzopyran-4-one moiety." []

found 29 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: 1-benzopyrans

Child Taxonomies: Furanochromones, Benzochromones, 2-methoxychromones, 3-methoxychromones, Chromeno[2,3-b]pyridine-5-ones

5,7-Dihydroxy-4H-1-benzopyran-4-one

4H-1-Benzopyran-4-one, 5,7-dihydroxy-

C9H6O4 (178.0266076)


5,7-Dihydroxychromone is a member of chromones. 5,7-Dihydroxychromone is a natural product found in Calluna vulgaris, Leucosidea sericea, and other organisms with data available. 5,7-Dihydroxy-4H-1-benzopyran-4-one is found in nuts. 5,7-Dihydroxy-4H-1-benzopyran-4-one is isolated from peanut shells. Isolated from peanut shells. 5,7-Dihydroxy-4H-1-benzopyran-4-one is found in peanut and nuts. 5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1]. 5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].

   

Noreugenin

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-methyl-

C10H8O4 (192.0422568)


Noreugenin is a member of the class of chromones in which the 1,4-benzopyrone skeleton is substituted with a methyl group at position 2 and with hydroxy groups at positions 5 and 7. A natural product, it is found in Pisonia aculeata. It has a role as a plant metabolite. It is a member of chromones and a member of resorcinols. It is a conjugate acid of a noreugenin(1-). Noreugenin is a natural product found in Crossosoma bigelovii, Schumanniophyton magnificum, and other organisms with data available. Noreugenin, also known as 5,7-dihydroxy-2-methyl-4h-1-benzopyran-4-one, is a member of the class of compounds known as chromones. Chromones are compounds containing a benzopyran-4-one moiety. Noreugenin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Noreugenin can be found in carrot and wild carrot, which makes noreugenin a potential biomarker for the consumption of these food products. Noreugenin, 5,7-dihydroxy-2-methyl-4H-chromen-4-one, is a new chromone from Aloe arborescens. (Amaryllidaceae)[1].

   

Cromoglicic acid

5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid

C23H16O11 (468.0692586)


Cromoglicic acid is only found in individuals that have used or taken this drug. It is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. [PubChem]Cromoglicate inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. Cromoglicate also may reduce the release of inflammatory leukotrienes. Cromoglicate may act by inhibiting calcium influx. A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EB - Antiallergic agents, excl. corticosteroids R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BC - Antiallergic agents, excl. corticosteroids R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AC - Antiallergic agents, excl. corticosteroids D - Dermatologicals > D11 - Other dermatological preparations > D11A - Other dermatological preparations > D11AH - Agents for dermatitis, excluding corticosteroids C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C29714 - Mast Cell Stabilizer S - Sensory organs > S01 - Ophthalmologicals > S01G - Decongestants and antiallergics D000893 - Anti-Inflammatory Agents > D000082142 - Mast Cell Stabilizers D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents D018926 - Anti-Allergic Agents D007155 - Immunologic Factors

   

2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

C19H17NO3 (307.1208372)


C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor D004791 - Enzyme Inhibitors

   

Eugenin

5-Hydroxy-7-methoxy-2-methyl-4H-1-benzopyran-4-one

C11H10O4 (206.057906)


Constituent of Eugenia aromatica (clove). Eugenin is found in many foods, some of which are wild carrot, carrot, herbs and spices, and java plum. Eugenin is found in carrot. Eugenin is a constituent of Eugenia aromatica (clove). Eugenin is a chromone isolated from Peucedanum japonicum, with potent antiplatelet aggregation activity[1]. Eugenin is a chromone isolated from Peucedanum japonicum, with potent antiplatelet aggregation activity[1].

   

Eugenitol

5,7-dihydroxy-2,6-dimethyl-4H-chromen-4-one

C11H10O4 (206.057906)


Eugenitol is found in herbs and spices. Eugenitol is a constituent of the flowers of Eugenia caryophyllata (clove)

   

(S)-2,3-Dihydro-7-hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid

2-(7-hydroxy-2-methyl-4-oxo-3,4-dihydro-2H-1-benzopyran-5-yl)acetic acid

C12H12O5 (236.06847019999998)


(S)-2,3-Dihydro-7-hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid is found in green vegetables. (S)-2,3-Dihydro-7-hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid is a constituent of Rheum sp. (rhubarb). Constituent of Rheum species (rhubarb). (S)-2,3-Dihydro-7-hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid is found in green vegetables.

   

Mycochromone

Dimethyl (2-ethenyl-5-hydroxy-4-oxo-4H-1-benzopyran-3-yl)propanedioate, 9ci

C16H14O7 (318.0739494)


Mycochromone is produced by Mycosphaerella rosigena. Mycotoxin. Production by Mycosphaerella rosigena. Mycotoxin.

   

Chromone

4H-benzo(b)Pyran-4-one

C9H6O2 (146.0367776)


Isol from Ye Hao (Carum carvi). Chromone is found in fats and oils and herbs and spices. Chromone is found in fats and oils. Isol from Ye Hao (Carum carvi

   

7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid

7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid, 9ci

C12H10O5 (234.052821)


7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid is found in green vegetables. 7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid is a constituent of Rheum sp. Constituent of Rheum species 7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-acetic acid is found in green vegetables.

   

Isoeugenitin

5-Hydroxy-7-methoxy-2,8-dimethyl-4H-1-benzopyran-4-one

C12H12O4 (220.0735552)


Constituent of Eugenia caryophyllata (clove). Isoeugenitin is found in herbs and spices and cloves. Isoeugenitin is found in cloves. Isoeugenitin is a constituent of Eugenia caryophyllata (clove)

   

Cassiachromone

7-Hydroxy-2-methyl-5-(2-oxopropyl)-4H-1-benzopyran-4-one, 9ci

C13H12O4 (232.0735552)


Cassiachromone is found in green vegetables. Cassiachromone is isolated from Rheum sp. (rhubarb

   

Isoeugenitol

5-Benzyl-5-(3-pyridinyl)-2,4-imidazolidinedione

C11H10O4 (206.057906)


Isoeugenitol is found in herbs and spices. Isoeugenitol is present in Eugenia caryophyllata (clove

   

7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one

7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one

C11H10O3 (190.062991)


7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one is found in green vegetables. 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one is a constituent of Rheum sp. (rhubarb). Constituent of Rheum species (rhubarb). 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one is found in green vegetables.

   

7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-carboxylic acid

7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-carboxylic acid

C11H8O5 (220.0371718)


7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-carboxylic acid is found in green vegetables. 7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-carboxylic acid is a constituent of Rheum sp Constituent of Rheum species 7-Hydroxy-2-methyl-4-oxo-4H-1-benzopyran-5-carboxylic acid is found in green vegetables.

   

Cyclointegrin

5,15-dihydroxy-17-methoxy-9,9-dimethyl-8,20-dioxatetracyclo[10.8.0.0²,⁷.0¹⁴,¹⁹]icosa-1(12),2(7),3,5,14,16,18-heptaen-13-one

C21H20O6 (368.125982)


Cyclointegrin is found in fruits. Cyclointegrin is isolated from heartwood of Artocarpus integer (champedak

   

5-Hydroxy-7-methoxy-2-tritriacontyl-4H-1-benzopyran-4-one

5-Hydroxy-7-methoxy-2-tritriacontyl-4H-1-benzopyran-4-one, 9ci

C43H74O4 (654.5586804)


5-Hydroxy-7-methoxy-2-tritriacontyl-4H-1-benzopyran-4-one is found in green vegetables. 5-Hydroxy-7-methoxy-2-tritriacontyl-4H-1-benzopyran-4-one is a constituent of the famine food Agave americana. Constituent of the famine food Agave americana. 5-Hydroxy-7-methoxy-2-tritriacontyl-4H-1-benzopyran-4-one is found in green vegetables.

   

Aloesol

7-Hydroxy-2-(2-hydroxypropyl)-5-methyl-4H-1-benzopyran-4-one, 9ci

C13H14O4 (234.0892044)


Aloesol is found in green vegetables. Aloesol is a constituent of Aloe species and Chinese rhubarb Constituent of Aloe subspecies and Chinese rhubarb. Aloesol is found in green vegetables.

   

Eugenitin

5-Hydroxy-7-methoxy-2,6-dimethyl-4H-1-benzopyran-4-one

C12H12O4 (220.0735552)


From Eugenia caryophyllata (clove). Eugenitin is found in herbs and spices and cloves. Eugenitin is found in cloves. Eugenitin is from Eugenia caryophyllata (clove

   

Pranlukast

N-[4-oxo-2-(2H-1,2,3,4-tetrazol-5-yl)-4H-chromen-7-yl]-4-(4-phenylbutoxy)benzamide

C27H23N5O4 (481.17499580000003)


Pranlukast is only found in individuals that have used or taken this drug. It is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.Pranlukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Pranlukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.

   

Chromocarb

4-oxo-4H-1-Benzopyran-2-carboxylic acid

C10H6O4 (190.0266076)


C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent

   

Elaeocarpine

7-methyl-2-oxa-15-azatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadeca-3(8),4,6-trien-9-one

C16H19NO2 (257.1415714)


   

Elagolix

4-({2-[5-(2-fluoro-3-methoxyphenyl)-3-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-4-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-1-yl]-1-phenylethyl}amino)butanoic acid

C32H30F5N3O5 (631.2105509999999)


   

Fulvic acid

3,7,8-trihydroxy-3-methyl-10-oxo-1H,3H,4H,10H-pyrano[4,3-b]chromene-9-carboxylic acid

C14H12O8 (308.0532152)


   

Iguratimod

N-(7-Methanesulphonamido-4-oxo-6-phenoxy-4H-chromen-3-yl)carboximidic acid

C17H14N2O6S (374.05725440000003)


C308 - Immunotherapeutic Agent

   

Protoapigenone

5,7-dihydroxy-2-(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)-4H-chromen-4-one

C15H10O6 (286.047736)


   

(3S)-3-[[(2S)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]propanoyl]-phenylmethoxycarbonylamino]-6-fluoro-4,5-dioxohexanoic acid

(3S)-3-[[(2S)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]propanoyl]-phenylmethoxycarbonylamino]-6-fluoro-4,5-dioxohexanoic acid

C22H28FN3O8 (481.186034)


   

5-[(2R)-3-(2-Carboxy-4-oxochromen-6-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid

5-{3-[(2-carboxy-4-oxo-4H-chromen-6-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid

C23H16O11 (468.0692586)


   

N'-[(4-Oxo-4H-chromen-3-yl)methylene]nicotinohydrazide

N-[(4-oxo-4H-chromen-3-yl)methylidene]pyridine-3-carbohydrazide

C16H11N3O3 (293.08003759999997)