beta-Glycerophosphoric acid (BioDeep_00000003576)

 

Secondary id: BioDeep_00000400450, BioDeep_00001868639

natural product human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


2-HYDROXY-1-(hydroxymethyl)ethyl dihydrogen phosphoric acid

化学式: C3H9O6P (172.01367439999999)
中文名称: β-甘油磷酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.9%

分子结构信息

SMILES: C(C(CO)OP(=O)(O)O)O
InChI: InChI=1S/C3H9O6P/c4-1-3(2-5)9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8)

描述信息

beta-Glycerophosphoric acid, also known as BGA or glycerol 2-phosphate, is a component of glycerolipid metabolism. It is formed in minor quanitites because the alpha glycerophosphorate is preferentially formed in this manner. beta-Glycerophosphoric acid is used as a biological buffer (Sigma-Aldrich).
Glycerol-2-phosphate is a component of glycerolipid metabolism. It is formed in minor quanitites, as the alpha glycerophosphorate is preferentially formed in this manner. Also used as a biological buffer (Sigma-Aldrich) [HMDB]
Acquisition and generation of the data is financially supported in part by CREST/JST.

同义名列表

35 个代谢物同义名

2-HYDROXY-1-(hydroxymethyl)ethyl dihydrogen phosphoric acid; 2-HYDROXY-1-(hydroxymethyl)ethyl dihydrogen phosphATE; 1,2,3-Propanetriol, 2-(dihydrogen phosphoric acid); beta-Glycerophosphoric acid, calcium salt (1:1); 1,3-Hydroxy-2-propyl dihydrogen phosphoric acid; beta-Glycerophosphoric acid, iron(3+) salt(3:2); [(1,3-dihydroxypropan-2-yl)oxy]phosphonic acid; L-Glycerol-2-phosphate Disodium Salt n-Hydrate; 1,2,3-Propanetriol, 2-(dihydrogen phosphate); beta-Glycerophosphoric acid, disodium salt; beta-Glycerophosphoric acid, calcium salt; 1,3-Hydroxy-2-propyl dihydrogen phosphate; beta-Glycerophosphoric acid, sodium salt; beta-Glycerophosphoric acid, iron salt; Dihydrogen beta-glycerophosphate; Dihydrogen β-glycerophosphate; beta-Glycerophosphoric acid; Glycerol 2-phosphoric acid; Glycerol-2-phosphoric acid; b-Glycerophosphoric acid; Β-glycerophosphoric acid; 2-Glycerophosphoric acid; beta-Glycerol phosphate; beta-Glycerophosphorate; beta-Glyceryl phosphate; beta-Glycerophosphate; β-glycerophosphorate; Glycerol-2-phosphate; β-Glyceryl phosphate; Glycerol 2-phosphate; b-Glycerophosphate; 2-Glycerophosphate; Β-glycerophosphate; BGA; Beta-Glycerophosphoric acid



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Jun Hong, Suzhen Huang, Hanqi Wu, Nan Yao, Xingzhang Luo, Zheng Zheng. Effects of eutrophic water with ammonium chloride, urea, potassium dihydrogen phosphate and sodium-β-glycerophosphate on Myriophyllum verticillatum and epiphytic bacteria. The Science of the total environment. 2023 May; ?(?):164507. doi: 10.1016/j.scitotenv.2023.164507. [PMID: 37268138]
  • Feng-Ling Ning, Jie Tao, Dan-Dan Li, Lu-Lu Tian, Meng-Ling Wang, Svetlana Reilly, Cheng Liu, Hui Cai, Hong Xin, Xue-Mei Zhang. Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling. Acta pharmacologica Sinica. 2022 Mar; 43(3):624-633. doi: 10.1038/s41401-021-00704-6. [PMID: 34163023]
  • Ximeng Ding, Zilu Liu, Yi Liu, Baiyang Xu, Juan Chen, Jingzhe Pu, Deling Wu, Hao Yu, Chuanshan Jin, Xiaoli Wang. Comprehensive evaluation of the mechanism of Gastrodia elata Blume in ameliorating cerebral ischemia-reperfusion injury based on integrating fecal metabonomics and 16S rDNA sequencing. Frontiers in cellular and infection microbiology. 2022; 12(?):1026627. doi: 10.3389/fcimb.2022.1026627. [PMID: 36389137]
  • Wan Wei, Qiuhong Yang, Jing Hu, Yong Yao, Huayuan Yang. Dexamethasone-Loaded Injectable In-situ Thermal Crosslinking Magnetic Responsive Hydrogel for the Physiochemical Stimulation of Acupoint to Suppress Pain in Sciatica Rats. Cell transplantation. 2022 Jan; 31(?):9636897221126088. doi: 10.1177/09636897221126088. [PMID: 36178143]
  • Yun Zhou, Li-Long Wei, Rui-Ping Zhang, Cheng-Wu Han, Yongtong Cao. Globular adiponectin inhibits osteoblastic differentiation of vascular smooth muscle cells through the PI3K/AKT and Wnt/β-catenin pathway. Journal of molecular histology. 2021 Oct; 52(5):1067-1080. doi: 10.1007/s10735-021-10012-2. [PMID: 34398360]
  • Yaling Bai, Jinsheng Xu, Shuo Yang, Huiran Zhang, Lei He, Wei Zhou, Meijuan Cheng, Shenglei Zhang. The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to alkalinization-induced vascular calcification in vitro. Journal of clinical laboratory analysis. 2021 Aug; 35(8):e23854. doi: 10.1002/jcla.23854. [PMID: 34313357]
  • Mariane Beatriz Sordi, Raissa Borges Curtarelli, Izabella Thaís da Silva, Gislaine Fongaro, Cesar Augusto Magalhães Benfatti, Ricardo de Souza Magini, Ariadne Cristiane Cabral da Cruz. Effect of dexamethasone as osteogenic supplementation in in vitro osteogenic differentiation of stem cells from human exfoliated deciduous teeth. Journal of materials science. Materials in medicine. 2021 Jan; 32(1):1. doi: 10.1007/s10856-020-06475-6. [PMID: 33469820]
  • Faye V Andrews, Stephanie M Kim, Lariah Edwards, Jennifer J Schlezinger. Identifying adipogenic chemicals: Disparate effects in 3T3-L1, OP9 and primary mesenchymal multipotent cell models. Toxicology in vitro : an international journal published in association with BIBRA. 2020 Sep; 67(?):104904. doi: 10.1016/j.tiv.2020.104904. [PMID: 32473317]
  • Ioana Alesutan, Franco Moritz, Tatjana Haider, Sun Shouxuan, Can Gollmann-Tepeköylü, Johannes Holfeld, Burkert Pieske, Florian Lang, Kai-Uwe Eckardt, Silke Sophie Heinzmann, Jakob Voelkl. Impact of β-glycerophosphate on the bioenergetic profile of vascular smooth muscle cells. Journal of molecular medicine (Berlin, Germany). 2020 07; 98(7):985-997. doi: 10.1007/s00109-020-01925-8. [PMID: 32488546]
  • Lisann Pelzl, Itishri Sahu, Ke Ma, David Heinzmann, Abdulla Al Mamun Bhuyan, Tamer Al-Maghout, Basma Sukkar, Yamini Sharma, Irene Marini, Flaviana Rigoni, Ferruh Artunc, Hang Cao, Ravi Gutti, Jakob Voelkl, Burkert Pieske, Meinrad Gawaz, Tamam Bakchoul, Florian Lang. Beta-Glycerophosphate-Induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes. Scientific reports. 2020 02; 10(1):1728. doi: 10.1038/s41598-020-58384-x. [PMID: 32015442]
  • Meihui Chen, Dan Luo, Jiheng Zhan, Yu Hou, Shudong Chen, Xing Li, Dingkun Lin. Fasudil enhanced differentiation of BMSCs in vivo and vitro, involvement of P38 signaling pathway. Chemico-biological interactions. 2020 Feb; 317(?):108944. doi: 10.1016/j.cbi.2020.108944. [PMID: 31935364]
  • Chan Wang, Yun Tang, Yanmei Wang, Guisen Li, Li Wang, Yi Li. Label-free quantitative proteomics identifies Smarca4 is involved in vascular calcification. Renal failure. 2019 Nov; 41(1):220-228. doi: 10.1080/0886022x.2019.1591997. [PMID: 30973285]
  • Peng Zhou, Xinyu Zhang, Mengqi Guo, Rong Guo, Lei Wang, Zihao Zhang, Zongwei Lin, Mei Dong, Hongyan Dai, Xiaoping Ji, Huixia Lu. Ginsenoside Rb1 ameliorates CKD-associated vascular calcification by inhibiting the Wnt/β-catenin pathway. Journal of cellular and molecular medicine. 2019 10; 23(10):7088-7098. doi: 10.1111/jcmm.14611. [PMID: 31423730]
  • Tian-Hua Xu, Xiao-Bo Qiu, Zi-Tong Sheng, Yi-Ran Han, Jian Wang, Bin-Yao Tian, Li Yao. Restoration of microRNA-30b expression alleviates vascular calcification through the mTOR signaling pathway and autophagy. Journal of cellular physiology. 2019 08; 234(8):14306-14318. doi: 10.1002/jcp.28130. [PMID: 30701530]
  • Christina M Payne, Liam P Burke, Brenton Cavanagh, Daniel O'Toole, Sally-Ann Cryan, Helena M Kelly. Evaluation of the Immunomodulatory Effects of All-Trans Retinoic Acid Solid Lipid Nanoparticles and Human Mesenchymal Stem Cells in an A549 Epithelial Cell Line Model. Pharmaceutical research. 2019 Feb; 36(4):50. doi: 10.1007/s11095-019-2583-x. [PMID: 30761406]
  • Hyo-Kyung Bae, Bae-Dong Jung, Seunghyung Lee, Choon-Keun Park, Boo-Keun Yang, Hee-Tae Cheong. Correlation of spontaneous adipocyte generation with osteogenic differentiation of porcine skin-derived stem cells. Journal of veterinary science. 2019 Jan; 20(1):16-26. doi: 10.4142/jvs.2019.20.1.16. [PMID: 30481989]
  • Anna Di Vito, Amerigo Giudice, Emanuela Chiarella, Natalia Malara, Francesco Bennardo, Leonzio Fortunato. In Vitro Long-Term Expansion and High Osteogenic Potential of Periodontal Ligament Stem Cells: More Than a Mirage. Cell transplantation. 2019 01; 28(1):129-139. doi: 10.1177/0963689718807680. [PMID: 30369260]
  • Anique D Ter Braake, Paul T Tinnemans, Catherine M Shanahan, Joost G J Hoenderop, Jeroen H F de Baaij. Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation. Scientific reports. 2018 02; 8(1):2069. doi: 10.1038/s41598-018-20241-3. [PMID: 29391410]
  • Wei Hao, Rui Yang, Yang Yang, Sheng Jin, Yanqing Li, Fang Yuan, Qi Guo, Lin Xiao, Xin Wang, Fuwei Wang, Yuming Wu, Xu Teng. Stellate ganglion block ameliorates vascular calcification by inhibiting endoplasmic reticulum stress. Life sciences. 2018 Jan; 193(?):1-8. doi: 10.1016/j.lfs.2017.12.002. [PMID: 29208463]
  • Y L Bai, J S Xu, T Tian, J X Zhang, L W Cui, H R Zhang, S L Zhang. [Effect and mechanism of intermittent alkaline stimulation on high phosphorus induced calcification in vascular smooth muscle cells of rats]. Zhonghua xin xue guan bing za zhi. 2017 Jun; 45(6):519-525. doi: 10.3760/cma.j.issn.0253-3758.2017.06.015. [PMID: 28648030]
  • J X Zhang, J S Xu, Y Y Han, Y L Bai, L W Cui, H R Zhang, S L Zhang. [Role of nuclear factor of activated T-cells cytoplasmic 1 on vascular calcification in rats with chronic renal failure]. Zhonghua yi xue za zhi. 2017 Feb; 97(6):451-456. doi: 10.3760/cma.j.issn.0376-2491.2017.06.011. [PMID: 28219134]
  • Guanghao Wu, Yuan Yuan, Jintian He, Ying Li, Xiaojing Dai, Baohua Zhao. Stable thermosensitive in situ gel-forming systems based on the lyophilizate of chitosan/α,β-glycerophosphate salts. International journal of pharmaceutics. 2016 Sep; 511(1):560-569. doi: 10.1016/j.ijpharm.2016.07.050. [PMID: 27457422]
  • Xiaonan Zhang, Kang Chen, Bo Wei, Xingwang Liu, Zeming Lei, Xizhuang Bai. Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway. Chemico-biological interactions. 2016 Aug; 256(?):188-97. doi: 10.1016/j.cbi.2016.07.003. [PMID: 27387537]
  • Yashu Yao, Mengxin Xia, Huizhen Wang, Guowen Li, Hongyi Shen, Guang Ji, Qianchao Meng, Yan Xie. Preparation and evaluation of chitosan-based nanogels/gels for oral delivery of myricetin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016 Aug; 91(?):144-53. doi: 10.1016/j.ejps.2016.06.014. [PMID: 27328876]
  • Wensong Zhang, Yi Li, Hanlu Ding, Yaqin Du, Li Wang. Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway. Renal failure. 2016 Aug; 38(7):1099-106. doi: 10.1080/0886022x.2016.1194143. [PMID: 27300444]
  • Ting Cai, Danqin Sun, Ying Duan, Ping Wen, Chunsun Dai, Junwei Yang, Weichun He. WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression. Experimental cell research. 2016 07; 345(2):206-17. doi: 10.1016/j.yexcr.2016.06.007. [PMID: 27321958]
  • S L Zhang, J S Xu, S Yang, Y L Bai, J X Zhang, L W Cui, Q Y Yu. [Effects of intermediate conductance calcium-activated potassium channel blocker TARAM-34 on β-glycerophosphate induced vascular smooth muscle cells calcification]. Zhonghua xin xue guan bing za zhi. 2016 Jun; 44(6):536-41. doi: 10.3760/cma.j.issn.0253-3758.2016.06.015. [PMID: 27346269]
  • K H Yeom, W Ariyoshi, T Okinaga, A Washio, T Morotomi, C Kitamura, T Nishihara. Platelet-rich plasma enhances the differentiation of dental pulp progenitor cells into odontoblasts. International endodontic journal. 2016 Mar; 49(3):271-8. doi: 10.1111/iej.12443. [PMID: 25702817]
  • Gergely Becs, Abolfazl Zarjou, Anupam Agarwal, Katalin Éva Kovács, Ádám Becs, Mónika Nyitrai, Enikő Balogh, Emese Bányai, John W Eaton, Paolo Arosio, Maura Poli, Viktória Jeney, József Balla, György Balla. Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells. Journal of cellular and molecular medicine. 2016 Feb; 20(2):217-30. doi: 10.1111/jcmm.12682. [PMID: 26499096]
  • Farzaneh Ghasemi Tahrir, Fariba Ganji, Ali Reza Mani, Elham Khodaverdi. In vitro and in vivo evaluation of thermosensitive chitosan hydrogel for sustained release of insulin. Drug delivery. 2016; 23(3):1038-46. doi: 10.3109/10717544.2014.932861. [PMID: 25005583]
  • Hong Ruan, Youcheng Yu, Yun Liu, Xiaojun Ding, Xuehua Guo, Qian Jiang. Preparation and characteristics of thermoresponsive gel of minocycline hydrochloride and evaluation of its effect on experimental periodontitis models. Drug delivery. 2016; 23(2):525-31. doi: 10.3109/10717544.2014.929195. [PMID: 24963751]
  • En-Gang Li, Jun Tian, Zhong-Hua Xu. Effects of Gingko biloba extract (EGb 761) on vascular smooth muscle cell calcification induced by β-glycerophosphate. Renal failure. 2016; 38(4):552-7. doi: 10.3109/0886022x.2016.1148724. [PMID: 26908182]
  • Amelia H Baker, James Watt, Cassie K Huang, Louis C Gerstenfeld, Jennifer J Schlezinger. Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells. Chemical research in toxicology. 2015 Jun; 28(6):1156-66. doi: 10.1021/tx500433r. [PMID: 25932594]
  • Werner E G Müller, Emad Tolba, Qingling Feng, Heinz C Schröder, Julia S Markl, Maria Kokkinopoulou, Xiaohong Wang. Amorphous Ca²⁺ polyphosphate nanoparticles regulate the ATP level in bone-like SaOS-2 cells. Journal of cell science. 2015 Jun; 128(11):2202-7. doi: 10.1242/jcs.170605. [PMID: 25908856]
  • Hari K Pillai, Mingliang Fang, Dmitri Beglov, Dima Kozakov, Sandor Vajda, Heather M Stapleton, Thomas F Webster, Jennifer J Schlezinger. Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro. Environmental health perspectives. 2014 Nov; 122(11):1225-32. doi: 10.1289/ehp.1408111. [PMID: 25062436]
  • Xujie Liu, Yan Chen, Qianli Huang, Wei He, Qingling Feng, Bo Yu. A novel thermo-sensitive hydrogel based on thiolated chitosan/hydroxyapatite/beta-glycerophosphate. Carbohydrate polymers. 2014 Sep; 110(?):62-9. doi: 10.1016/j.carbpol.2014.03.065. [PMID: 24906729]
  • Ping Wen, Hongdi Cao, Li Fang, Hong Ye, Yang Zhou, Lei Jiang, Weifang Su, Hongying Xu, Weichun He, Chunsun Dai, Junwei Yang. miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment. Experimental cell research. 2014 Apr; 322(2):302-12. doi: 10.1016/j.yexcr.2014.01.025. [PMID: 24486760]
  • André L A Dos-Santos, Claudia F Dick, Thaís S Silveira, André L Fonseca-de-Souza, José R Meyer-Fernandes. Trypanosoma rangeli: an alkaline ecto-phosphatase activity is involved with survival and growth of the parasite. Experimental parasitology. 2013 Oct; 135(2):459-65. doi: 10.1016/j.exppara.2013.08.014. [PMID: 23994113]
  • Mathias Haarhaus, Hans J Arnqvist, Per Magnusson. Calcifying human aortic smooth muscle cells express different bone alkaline phosphatase isoforms, including the novel B1x isoform. Journal of vascular research. 2013; 50(2):167-74. doi: 10.1159/000346161. [PMID: 23328739]
  • Fang Liu, Ping Fu, Wenxing Fan, Rong Gou, Youqun Huang, Hongyu Qiu, Hui Zhong, Songmin Huang. Involvement of parathyroid hormone-related protein in vascular calcification of chronic haemodialysis patients. Nephrology (Carlton, Vic.). 2012 Aug; 17(6):552-60. doi: 10.1111/j.1440-1797.2012.01601.x. [PMID: 22448974]
  • Wen-Hua Zhao, Bao-Di Gou, Tian-Lan Zhang, Kui Wang. Lanthanum chloride bidirectionally influences calcification in bovine vascular smooth muscle cells. Journal of cellular biochemistry. 2012 May; 113(5):1776-86. doi: 10.1002/jcb.24049. [PMID: 22213182]
  • Pooja Iyer, Kenneth J Walker, Sundararajan V Madihally. Increased matrix synthesis by fibroblasts with decreased proliferation on synthetic chitosan-gelatin porous structures. Biotechnology and bioengineering. 2012 May; 109(5):1314-25. doi: 10.1002/bit.24396. [PMID: 22125268]
  • Stephen C Parnell, Sanjeev Puri, Darren P Wallace, James P Calvet. Protein phosphatase-1α interacts with and dephosphorylates polycystin-1. PloS one. 2012; 7(6):e36798. doi: 10.1371/journal.pone.0036798. [PMID: 22675472]
  • Nesrine Z Mostafa, Ross Fitzsimmons, Paul W Major, Adetola Adesida, Nadr Jomha, Hongxing Jiang, Hasan Uludağ. Osteogenic differentiation of human mesenchymal stem cells cultured with dexamethasone, vitamin D3, basic fibroblast growth factor, and bone morphogenetic protein-2. Connective tissue research. 2012; 53(2):117-31. doi: 10.3109/03008207.2011.611601. [PMID: 21966879]
  • Kanitsak Boonanantanasarn, Kajohnkiart Janebodin, Prapan Suppakpatana, Tawepong Arayapisit, Jit-aree Rodsutthi, Panjit Chunhabundit, Surintorn Boonanuntanasarn, Wanida Sripairojthikoon. Morinda citrifolia leaves enhance osteogenic differentiation and mineralization of human periodontal ligament cells. Dental materials journal. 2012; 31(5):863-71. doi: 10.4012/dmj.2012-053. [PMID: 23037852]
  • Elisa Fiorentini, Donatella Granchi, Elisa Leonardi, Nicola Baldini, Gabriela Ciapetti. Effects of osteogenic differentiation inducers on in vitro expanded adult mesenchymal stromal cells. The International journal of artificial organs. 2011 Oct; 34(10):998-1011. doi: 10.5301/ijao.5000001. [PMID: 22161283]
  • Ming-Ming Zhao, Ming-Jiang Xu, Yan Cai, Gexin Zhao, Youfei Guan, Wei Kong, Chaoshu Tang, Xian Wang. Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo. Kidney international. 2011 May; 79(10):1071-9. doi: 10.1038/ki.2011.18. [PMID: 21368742]
  • Ziyad Al-Aly. Phosphate, oxidative stress, and nuclear factor-κB activation in vascular calcification. Kidney international. 2011 May; 79(10):1044-7. doi: 10.1038/ki.2010.548. [PMID: 21527943]
  • Caitlin E Filby, Robert Williamson, Peter van Kooy, Alice Pébay, Mirella Dottori, Ngaire J Elwood, Faten Zaibak. Stimulation of Activin A/Nodal signaling is insufficient to induce definitive endoderm formation of cord blood-derived unrestricted somatic stem cells. Stem cell research & therapy. 2011 Apr; 2(2):16. doi: 10.1186/scrt57. [PMID: 21463501]
  • Brooke M Steenhard, Adrian Zelenchuk, Larysa Stroganova, Kathryn Isom, Patricia L St John, Glen K Andrews, Kenneth R Peterson, Dale R Abrahamson. Transgenic expression of human LAMA5 suppresses murine Lama5 mRNA and laminin α5 protein deposition. PloS one. 2011; 6(9):e23926. doi: 10.1371/journal.pone.0023926. [PMID: 21915268]
  • Kenichiro Kawai, Barrett J Larson, Hisako Ishise, Antoine Lyonel Carre, Soh Nishimoto, Michael Longaker, H Peter Lorenz. Calcium-based nanoparticles accelerate skin wound healing. PloS one. 2011; 6(11):e27106. doi: 10.1371/journal.pone.0027106. [PMID: 22073267]
  • Oliver Fiehn, W Timothy Garvey, John W Newman, Kerry H Lok, Charles L Hoppel, Sean H Adams. Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PloS one. 2010 Dec; 5(12):e15234. doi: 10.1371/journal.pone.0015234. [PMID: 21170321]
  • Gautam Gupta, Sreenatha Kirakodu, Ahmed El-Ghannam. Effects of exogenous phosphorus and silicon on osteoblast differentiation at the interface with bioactive ceramics. Journal of biomedical materials research. Part A. 2010 Dec; 95(3):882-90. doi: 10.1002/jbm.a.32915. [PMID: 20845489]
  • Birgit Agne, Charles Andrès, Cyril Montandon, Bastien Christ, Anouk Ertan, Friederike Jung, Sibylle Infanger, Sylvain Bischof, Sacha Baginsky, Felix Kessler. The acidic A-domain of Arabidopsis TOC159 occurs as a hyperphosphorylated protein. Plant physiology. 2010 Jul; 153(3):1016-30. doi: 10.1104/pp.110.158048. [PMID: 20457805]
  • Pathirage Kamal Perera, Yunman Li, Cheng Peng, Weirong Fang, Caifeng Han. Immunomodulatory activity of a Chinese herbal drug Yi Shen Juan Bi in adjuvant arthritis. Indian journal of pharmacology. 2010 Apr; 42(2):65-9. doi: 10.4103/0253-7613.64489. [PMID: 20711367]
  • Seth B Roberts, Christopher M Gowen, J Paul Brooks, Stephen S Fong. Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production. BMC systems biology. 2010 Mar; 4(?):31. doi: 10.1186/1752-0509-4-31. [PMID: 20307315]
  • Jessica Guzmán-Morales, Hani El-Gabalawy, Minh H Pham, Nicolas Tran-Khanh, Marc D McKee, William Wu, Michael Centola, Caroline D Hoemann. Effect of chitosan particles and dexamethasone on human bone marrow stromal cell osteogenesis and angiogenic factor secretion. Bone. 2009 Oct; 45(4):617-26. doi: 10.1016/j.bone.2009.06.014. [PMID: 19540373]
  • Andrew Butcher, Richard Milner, Keith Ellis, J Tracy Watson, Alan Horner. Interaction of platelet-rich concentrate with bone graft materials: an in vitro study. Journal of orthopaedic trauma. 2009 Mar; 23(3):195-200; discussion 201. doi: 10.1097/bot.0b013e31819b35db. [PMID: 19516093]
  • Raúl Aguilar-Vázquez, Oscar Alejandro Carballo-Molina, Omar Collazo-Navarrete, Maribel Guerrero-Rangel, Alberto Daniel Saucedo-Campos, Paulina Barrera-Lechuga, Rebeca López-Marure, Julio Roberto Cáceres-Cortés. [Osteogenesis of human vascular endothelial cells in culture]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 2008 Nov; 60(6):496-501. doi: NULL. [PMID: 19378836]
  • Thibault Sutra, Marion Morena, Anne-Sophie Bargnoux, Bertrand Caporiccio, Bernard Canaud, Jean-Paul Cristol. Superoxide production: a procalcifying cell signalling event in osteoblastic differentiation of vascular smooth muscle cells exposed to calcification media. Free radical research. 2008 Sep; 42(9):789-97. doi: 10.1080/10715760802400766. [PMID: 19051077]
  • James A Henderson, Xuezhong He, Esmaiel Jabbari. Concurrent differentiation of marrow stromal cells to osteogenic and vasculogenic lineages. Macromolecular bioscience. 2008 Jun; 8(6):499-507. doi: 10.1002/mabi.200700127. [PMID: 17941111]
  • Fereshteh Azari, Hojatollah Vali, Jean-Luc Guerquin-Kern, Ting-Di Wu, Alain Croisy, S Kelly Sears, Maryam Tabrizian, Marc D McKee. Intracellular precipitation of hydroxyapatite mineral and implications for pathologic calcification. Journal of structural biology. 2008 Jun; 162(3):468-79. doi: 10.1016/j.jsb.2008.03.003. [PMID: 18424074]
  • M Alonso, S Claros, J Becerra, J A Andrades. The effect of type I collagen on osteochondrogenic differentiation in adipose-derived stromal cells in vivo. Cytotherapy. 2008; 10(6):597-610. doi: 10.1080/14653240802242084. [PMID: 18836915]
  • Miyako Kusano, Atsushi Fukushima, Masanori Arita, Pär Jonsson, Thomas Moritz, Makoto Kobayashi, Naomi Hayashi, Takayuki Tohge, Kazuki Saito. Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. BMC systems biology. 2007 Nov; 1(?):53. doi: 10.1186/1752-0509-1-53. [PMID: 18028551]
  • Ping Olesen, Kirsten Nguyen, Lise Wogensen, Thomas Ledet, Lars Melholt Rasmussen. Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. American journal of physiology. Heart and circulatory physiology. 2007 Feb; 292(2):H1058-64. doi: 10.1152/ajpheart.00047.2006. [PMID: 17056676]
  • V Shalhoub, E Shatzen, C Henley, M Boedigheimer, J McNinch, R Manoukian, M Damore, D Fitzpatrick, K Haas, B Twomey, P Kiaei, S Ward, D L Lacey, D Martin. Calcification inhibitors and Wnt signaling proteins are implicated in bovine artery smooth muscle cell calcification in the presence of phosphate and vitamin D sterols. Calcified tissue international. 2006 Dec; 79(6):431-42. doi: 10.1007/s00223-006-0126-z. [PMID: 17171500]
  • Jie-Ying Wu, Can Liao, Zun-Peng Xu, Jin-Song Chen, Shao-Ling Gu. [A modified method to isolate and identify the adult mesenchymal stem cells from human bone marrow]. Zhongguo shi yan xue ye xue za zhi. 2006 Jun; 14(3):557-60. doi: ". [PMID: 16800942]
  • Shoshana Yakar, Mary L Bouxsein, Ernesto Canalis, Hui Sun, Vaida Glatt, Caren Gundberg, Pinchas Cohen, David Hwang, Yves Boisclair, Derek Leroith, Clifford J Rosen. The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. The Journal of endocrinology. 2006 May; 189(2):289-99. doi: 10.1677/joe.1.06657. [PMID: 16648296]
  • Marcus Jäger, Radu Bachmann, Axel Scharfstädt, Rüdiger Krauspe. Ovine cord blood accommodates multipotent mesenchymal progenitor cells. In vivo (Athens, Greece). 2006 Mar; 20(2):205-14. doi: ". [PMID: 16634520]
  • Valerie E Meyers, Majd Zayzafoon, Joanne T Douglas, Jay M McDonald. RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2005 Oct; 20(10):1858-66. doi: 10.1359/jbmr.050611. [PMID: 16160744]
  • Ihor Zahanich, Eva M Graf, Jürgen F Heubach, Ute Hempel, Sabine Boxberger, Ursula Ravens. Molecular and functional expression of voltage-operated calcium channels during osteogenic differentiation of human mesenchymal stem cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2005 Sep; 20(9):1637-46. doi: 10.1359/jbmr.050521. [PMID: 16059635]
  • Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005 Jul; 46(1):e11-4. doi: 10.1053/j.ajkd.2005.03.009. [PMID: 15983949]
  • Jason L Dragoo, Jay R Lieberman, Richard S Lee, Dan A Deugarte, Yupo Lee, Patricia A Zuk, Marc H Hedrick, Prosper Benhaim. Tissue-engineered bone from BMP-2-transduced stem cells derived from human fat. Plastic and reconstructive surgery. 2005 May; 115(6):1665-73. doi: 10.1097/01.prs.0000161459.90856.ab. [PMID: 15861072]
  • Michiko Mirams, Bruce G Robinson, Rebecca S Mason, Anne E Nelson. Bone as a source of FGF23: regulation by phosphate?. Bone. 2004 Nov; 35(5):1192-9. doi: 10.1016/j.bone.2004.06.014. [PMID: 15542045]
  • N J Hamlin, P A Price. Mineralization of decalcified bone occurs under cell culture conditions and requires bovine serum but not cells. Calcified tissue international. 2004 Sep; 75(3):231-42. doi: 10.1007/s00223-004-0190-1. [PMID: 15164149]
  • Thomas Tallant, Amitabha Deb, Niladri Kar, Joseph Lupica, Michael J de Veer, Joseph A DiDonato. Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-kappa B and proinflammatory gene program activation in intestinal epithelial cells. BMC microbiology. 2004 Aug; 4(?):33. doi: 10.1186/1471-2180-4-33. [PMID: 15324458]
  • Ming-Wei Zhang, Zi-Kuan Guo, Xiao-Dan Liu, Ying Wu, Chun-Mei Hou, Ning Mao. [Development of methodology for isolation and culture of mesenchymal stem cells derived from mouse skeletal muscle]. Zhongguo shi yan xue ye xue za zhi. 2003 Oct; 11(5):538-41. doi: NULL. [PMID: 14575555]
  • Sheng Ying Wu, Bao Hong Zhang, Chun Shui Pan, Hong Feng Jiang, Yong Zheng Pang, Chao Shu Tang, Yong Fen Qi. Endothelin-1 is a potent regulator in vivo in vascular calcification and in vitro in calcification of vascular smooth muscle cells. Peptides. 2003 Aug; 24(8):1149-56. doi: 10.1016/j.peptides.2003.07.008. [PMID: 14612185]
  • Claudio Passariello, Serena Schippa, Patrizia Iori, Francesca Berlutti, Maria Cristina Thaller, Gian Maria Rossolini. The molecular class C acid phosphatase of Chryseobacterium meningosepticum (OlpA) is a broad-spectrum nucleotidase with preferential activity on 5'-nucleotides. Biochimica et biophysica acta. 2003 May; 1648(1-2):203-9. doi: 10.1016/s1570-9639(03)00147-x. [PMID: 12758163]
  • J A Andrades, B Han, M E Nimni, D C Ertl, R J Simpkins, M P Arrabal, J Becerra. A modified rhTGF-beta1 and rhBMP-2 are effective in initiating a chondro-osseous differentiation pathway in bone marrow cells cultured in vitro. Connective tissue research. 2003; 44(3-4):188-97. doi: 10.1080/03008200390229912. [PMID: 14504040]
  • Y Watanabe, M Suzuki, Y Oyama, E Kusano, K Tamba, O Iimura, C Ito, M Imai, Y Asano. Cellular component of vascular calcification. Fibroblasts are essential for calcium deposition in cultured cells. Nephron. 2002 Dec; 92(4):840-5. doi: 10.1159/000065461. [PMID: 12399630]
  • E Ruel-Gariépy, G Leclair, P Hildgen, A Gupta, J-C Leroux. Thermosensitive chitosan-based hydrogel containing liposomes for the delivery of hydrophilic molecules. Journal of controlled release : official journal of the Controlled Release Society. 2002 Aug; 82(2-3):373-83. doi: 10.1016/s0168-3659(02)00146-3. [PMID: 12175750]
  • R C Pereira, A M Delany, Ernesto Canalis. Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression. Bone. 2002 May; 30(5):685-91. doi: 10.1016/s8756-3282(02)00687-7. [PMID: 11996905]
  • J Camps, I About, B Thonneman, T A Mitsiadis, G Schmaltz, J C Franquin. Two- versus three-dimensional in vitro differentiation of human pulp cells into odontoblastic cells. Connective tissue research. 2002; 43(2-3):396-400. doi: 10.1080/03008200290001069. [PMID: 12489188]
  • M Jaumot, J F Hancock. Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions. Oncogene. 2001 Jul; 20(30):3949-58. doi: 10.1038/sj.onc.1204526. [PMID: 11494123]
  • J A Andrades, J A Santamaría, M E Nimni, J Becerra. Selection and amplification of a bone marrow cell population and its induction to the chondro-osteogenic lineage by rhOP-1: an in vitro and in vivo study. The International journal of developmental biology. 2001 Jun; 45(4):689-93. doi: NULL. [PMID: 11461007]
  • L D Buttery, S Bourne, J D Xynos, H Wood, F J Hughes, S P Hughes, V Episkopou, J M Polak. Differentiation of osteoblasts and in vitro bone formation from murine embryonic stem cells. Tissue engineering. 2001 Feb; 7(1):89-99. doi: 10.1089/107632700300003323. [PMID: 11224927]
  • M J Coelho, M H Fernandes. Human bone cell cultures in biocompatibility testing. Part II: effect of ascorbic acid, beta-glycerophosphate and dexamethasone on osteoblastic differentiation. Biomaterials. 2000 Jun; 21(11):1095-102. doi: 10.1016/s0142-9612(99)00192-1. [PMID: 10817261]
  • M L Couble, J C Farges, F Bleicher, B Perrat-Mabillon, M Boudeulle, H Magloire. Odontoblast differentiation of human dental pulp cells in explant cultures. Calcified tissue international. 2000 Feb; 66(2):129-38. doi: 10.1007/pl00005833. [PMID: 10652961]
  • L R Chaudhary, L V Avioli. Extracellular-signal regulated kinase signaling pathway mediates downregulation of type I procollagen gene expression by FGF-2, PDGF-BB, and okadaic acid in osteoblastic cells. Journal of cellular biochemistry. 2000 Jan; 76(3):354-9. doi: 10.1002/(sici)1097-4644(20000301)76:3<354::aid-jcb2>3.0.co;2-u. [PMID: 10649432]
  • H H Chien, W L Lin, M I Cho. Interleukin-1beta-induced release of matrix proteins into culture media causes inhibition of mineralization of nodules formed by periodontal ligament cells in vitro. Calcified tissue international. 1999 May; 64(5):402-13. doi: 10.1007/pl00005822. [PMID: 10203417]
  • N Fratzl-Zelman, P Fratzl, H Hörandner, B Grabner, F Varga, A Ellinger, K Klaushofer. Matrix mineralization in MC3T3-E1 cell cultures initiated by beta-glycerophosphate pulse. Bone. 1998 Dec; 23(6):511-20. doi: 10.1016/s8756-3282(98)00139-2. [PMID: 9855459]
  • G Leyhausen, B Lorenz, H Zhu, W Geurtsen, R Bohnensack, W E Müller, H C Schröder. Inorganic polyphosphate in human osteoblast-like cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 1998 May; 13(5):803-12. doi: 10.1359/jbmr.1998.13.5.803. [PMID: 9610744]
  • K C Hicok, T Thomas, F Gori, D J Rickard, T C Spelsberg, B L Riggs. Development and characterization of conditionally immortalized osteoblast precursor cell lines from human bone marrow stroma. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 1998 Feb; 13(2):205-17. doi: 10.1359/jbmr.1998.13.2.205. [PMID: 9495513]
  • A Rattner, O Sabido, C Massoubre, F Rascle, J Frey. Characterization of human osteoblastic cells: influence of the culture conditions. In vitro cellular & developmental biology. Animal. 1997 Nov; 33(10):757-62. doi: 10.1007/s11626-997-0154-7. [PMID: 9466680]
  • J Hao, S Shi, Z Niu, Z Xun, L Yue, M Xiao. Mineralized nodule formation by human dental papilla cells in culture. European journal of oral sciences. 1997 Aug; 105(4):318-24. doi: 10.1111/j.1600-0722.1997.tb00247.x. [PMID: 9298363]
  • P Manduca, C Palermo, C Caruso, A Brizzolara, C Sanguineti, C Filanti, A Zicca. Rat tibial osteoblasts III: propagation in vitro is accompanied by enhancement of osteoblast phenotype. Bone. 1997 Jul; 21(1):31-9. doi: 10.1016/s8756-3282(97)00037-9. [PMID: 9213005]
  • T Yamashita, H Ishii, K Shimoda, T K Sampath, T Katagiri, M Wada, T Osawa, T Suda. Subcloning of three osteoblastic cell lines with distinct differentiation phenotypes from the mouse osteoblastic cell line KS-4. Bone. 1996 Nov; 19(5):429-36. doi: 10.1016/s8756-3282(96)00255-4. [PMID: 8922640]
  • B Y Klein, A Mariash, A Brzezinski, H Ben-Bassat, N Rojansky. Differential induction of cell-mediated mineralization in rat marrow stroma by sera from women of low and high risk for vertebral fracture. Journal of cellular biochemistry. 1996 Oct; 63(1):115-22. doi: 10.1002/(sici)1097-4644(199610)63:1\%3c115::aid-jcb10\%3e3.0.co;2-k. [PMID: 8891909]