6-Phosphogluconic acid (BioDeep_00000003413)

 

Secondary id: BioDeep_00000265283

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


(2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexanoic acid

化学式: C6H13O10P (276.0246)
中文名称: 6-磷酸葡萄糖酸, D-6-磷酸葡萄糖酸, 6-Phosphogluconic acid 三钠盐
谱图信息: 最多检出来源 Homo sapiens(blood) 11.42%

Reviewed

Last reviewed on 2024-07-02.

Cite this Page

6-Phosphogluconic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/6-phosphogluconic_acid (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000003413). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C(C(C(C(C(=O)O)O)O)O)O)OP(=O)(O)O
InChI: InChI=1S/C6H13O10P/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15)/t2-,3-,4+,5-/m1/s1

描述信息

6-phosphogluconic acid, also known as 6-phospho-D-gluconate or D-gluconic acid 6-(dihydrogen phosphate), is a member of the class of compounds known as monosaccharide phosphates. Monosaccharide phosphates are monosaccharides comprising a phosphated group linked to the carbohydrate unit. 6-phosphogluconic acid is soluble (in water) and a moderately acidic compound (based on its pKa). 6-phosphogluconic acid can be found in a number of food items such as purple mangosteen, nopal, chicory leaves, and common sage, which makes 6-phosphogluconic acid a potential biomarker for the consumption of these food products. 6-phosphogluconic acid can be found primarily in blood, cellular cytoplasm, and saliva, as well as throughout most human tissues. 6-phosphogluconic acid exists in all living species, ranging from bacteria to humans. In humans, 6-phosphogluconic acid is involved in the pentose phosphate pathway. 6-phosphogluconic acid is also involved in few metabolic disorders, which include glucose-6-phosphate dehydrogenase deficiency, ribose-5-phosphate isomerase deficiency, transaldolase deficiency, and warburg effect. 6-phosphogluconic acid is formed by 6-phosphogluconolactonase, and acted upon by phosphogluconate dehydrogenase to produce ribulose 5-phosphate. It may also be acted upon by 6-phosphogluconate dehydratase to produce 2-keto-3-deoxy-6-phosphogluconate .
6-Phosphogluconic acid, also known as 6-phospho-D-gluconate or gluconic acid-6-phosphate, belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. 6-Phosphogluconic acid exists in all living species, ranging from bacteria to humans. Within humans, 6-phosphogluconic acid participates in a number of enzymatic reactions. In particular, 6-phosphogluconic acid can be biosynthesized from gluconolactone; which is mediated by the enzyme 6-phosphogluconolactonase. In addition, 6-phosphogluconic acid can be converted into D-ribulose 5-phosphate through the action of the enzyme 6-phosphogluconate dehydrogenase, decarboxylating. In humans, 6-phosphogluconic acid is involved in the metabolic disorder called the transaldolase deficiency pathway. Outside of the human body, 6-Phosphogluconic acid has been detected, but not quantified in several different foods, such as cascade huckleberries, common chokecherries, half-highbush blueberries, american cranberries, and okra.
[Spectral] 6-Phospho-D-gluconate (exact mass = 276.02463) and Phosphoenolpyruvate (exact mass = 167.98237) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
KEIO_ID P031

同义名列表

16 个代谢物同义名

(2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexanoic acid; 2,3,4,5-tetrahydroxy-6-phosphonooxyhexanoic acid; 6-Phosphogluconic acid Barium salt hydrate; D-Gluconic acid 6-(dihydrogen phosphate); 6-O-Phosphono-D-gluconic acid; D-Gluconic acid 6-phosphate; Gluconic acid-6-phosphate; 6-Phospho-D-gluconic acid; D-Gluconate 6-phosphate; 6-Phosphogluconic acid; 6-Phospho-D-gluconate; 6-phospho D-gluconate; Gluconate 6-phosphate; 6-Phosphogluconate; 6-p-Gluconate; 6-Phosphogluconic acid



数据库引用编号

31 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

40 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(11)

WikiPathways(6)

Plant Reactome(0)

INOH(1)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(22)

PharmGKB(0)

51 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ALB, CAT, FH, G6PD, GAPDH, GCK, GK, KHK, PGD, PKM, RGN, TXN
Peripheral membrane protein 3 G6PD, GCK, HSD17B6
Endoplasmic reticulum membrane 2 HSP90B1, TKT
Nucleus 10 ALB, FH, GAPDH, GCK, GK, HSP90B1, PGD, PKM, RGN, TXN
cytosol 15 ALB, CAT, FH, G6PD, GAPDH, GCK, GK, GSR, HSP90B1, KHK, PGD, PKM, TKT, TXN, XYLB
nuclear body 1 TKT
centrosome 1 ALB
nucleoplasm 4 CD2, GCK, TKT, TXN
Cell membrane 2 CD2, TKT
Early endosome membrane 1 HSD17B6
Golgi apparatus membrane 1 GCK
cell surface 1 CD2
Golgi apparatus 2 ALB, CD2
Golgi membrane 2 GCK, INS
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 3 G6PD, GAPDH, GK
plasma membrane 3 CD2, GAPDH, TKT
Membrane 4 CAT, G6PD, GAPDH, HSP90B1
apical plasma membrane 1 TKT
basolateral plasma membrane 1 GCK
extracellular exosome 13 ALB, CAT, FH, G6PD, GAPDH, GK, GSR, HSP90B1, KHK, PGD, PKM, TKT, TXN
Lumenal side 1 HSD17B6
endoplasmic reticulum 4 ALB, H6PD, HSD17B6, HSP90B1
extracellular space 2 ALB, INS
perinuclear region of cytoplasm 2 GAPDH, HSP90B1
mitochondrion 6 CAT, FH, GCK, GK, GSR, PKM
protein-containing complex 4 ALB, CAT, CD2, HSP90B1
intracellular membrane-bounded organelle 4 CAT, G6PD, GAPDH, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 2 CD2, TKT
Secreted 3 ALB, INS, TXN
extracellular region 7 ALB, CAT, CD2, HSP90B1, INS, PKM, TXN
cytoplasmic side of plasma membrane 2 CD2, G6PD
Mitochondrion outer membrane 1 GK
Single-pass membrane protein 1 GK
mitochondrial outer membrane 1 GK
mitochondrial matrix 3 CAT, FH, GSR
anchoring junction 1 ALB
centriolar satellite 1 G6PD
nuclear membrane 1 GAPDH
external side of plasma membrane 2 CD2, GSR
Extracellular vesicle 1 PKM
actin cytoskeleton 1 TKT
microtubule cytoskeleton 1 GAPDH
midbody 1 HSP90B1
cell-cell junction 1 CD2
vesicle 3 GAPDH, PKM, TKT
Cytoplasm, perinuclear region 1 GAPDH
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 3 CAT, HSP90B1, TKT
Peroxisome 2 CAT, TKT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 2 HSP90B1, PKM
receptor complex 1 TKT
ciliary basal body 1 ALB
cilium 1 PKM
Chromosome 1 FH
cytoskeleton 1 GAPDH
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 1 GCK
site of double-strand break 1 FH
endosome lumen 1 INS
Lipid droplet 1 GAPDH
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
[Isoform 4]: Cytoplasm, cytosol 1 GK
ficolin-1-rich granule lumen 2 CAT, PKM
secretory granule lumen 3 CAT, INS, PKM
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, H6PD, HSP90B1, INS
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Sarcoplasmic reticulum lumen 1 HSP90B1
ribonucleoprotein complex 1 GAPDH
Rough endoplasmic reticulum 1 PKM
GAIT complex 1 GAPDH
endocytic vesicle lumen 1 HSP90B1
catalase complex 1 CAT
endoplasmic reticulum chaperone complex 1 HSP90B1
[Isoform Mitochondrial]: Mitochondrion 1 FH
[Isoform Cytoplasmic]: Cytoplasm, cytosol 1 FH
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
[Isoform 3]: Mitochondrion outer membrane 1 GK
ciliary transition fiber 1 ALB


文献列表

  • Yuuma Ishikawa, Atsuko Miyagi, Toshiki Ishikawa, Minoru Nagano, Masatoshi Yamaguchi, Yukako Hihara, Yasuko Kaneko, Maki Kawai-Yamada. One of the NAD kinases, sll1415, is required for the glucose metabolism of Synechocystis sp. PCC 6803. The Plant journal : for cell and molecular biology. 2019 05; 98(4):654-666. doi: 10.1111/tpj.14262. [PMID: 30693583]
  • Qi-Liang Chen, Zhi Luo, Xu Liu, Yu-Feng Song, Cai-Xia Liu, Jia-Lang Zheng, Yan-Hong Zhao. Effects of waterborne chronic copper exposure on hepatic lipid metabolism and metal-element composition in Synechogobius hasta. Archives of environmental contamination and toxicology. 2013 Feb; 64(2):301-15. doi: 10.1007/s00244-012-9835-7. [PMID: 23229194]
  • Reza Hakkak, Ahmed Al-Dwairi, George J Fuchs, Soheila Korourian, Frank A Simmen. Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female Zucker rats bearing DMBA-initiated mammary tumors. Genes & nutrition. 2012 Oct; 7(4):549-58. doi: 10.1007/s12263-012-0294-6. [PMID: 22528625]
  • Kang Wook Lee, Seung-Gyu Lee, Nam Soo Han, Jeong-Hwan Kim. Proteomic analysis of proteins of Weissella confusa 31 affected by bile salts. Journal of microbiology and biotechnology. 2012 Oct; 22(10):1432-40. doi: 10.4014/jmb.1203.03066. [PMID: 23075796]
  • Hiroyoshi Matsumura, Eiichi Mizohata, Hiroyuki Ishida, Ayako Kogami, Takeshi Ueno, Amane Makino, Tsuyoshi Inoue, Akiho Yokota, Tadahiko Mae, Yasushi Kai. Crystal structure of rice Rubisco and implications for activation induced by positive effectors NADPH and 6-phosphogluconate. Journal of molecular biology. 2012 Sep; 422(1):75-86. doi: 10.1016/j.jmb.2012.05.014. [PMID: 22609438]
  • Qiong-Lin Liang, Xiao-Ping Liang, Yi-Ming Wang, Yuan-Yuan Xie, Rong-Li Zhang, Xi Chen, Rong Gao, Yi-Jun Cheng, Jun Wu, Qing-Bo Xu, Qing-Zhong Xiao, Xue Li, Shu-Feng Lv, Xue-Mei Fan, Hong-Yang Zhang, Qing-Li Zhang, Guo-An Luo. Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on 'system to system' mode. Journal of translational medicine. 2012 Feb; 10(?):26. doi: 10.1186/1479-5876-10-26. [PMID: 22316391]
  • Stephanus J Ferreira, Uwe Sonnewald. The mode of sucrose degradation in potato tubers determines the fate of assimilate utilization. Frontiers in plant science. 2012; 3(?):23. doi: 10.3389/fpls.2012.00023. [PMID: 22639642]
  • Wei Guo, Li-fang Zou, Yu-rong Li, Yi-ping Cui, Zhi-yuan Ji, Lu-lu Cai, Hua-song Zou, William C Hutchins, Ching-hong Yang, Gong-you Chen. Fructose-bisphophate aldolase exhibits functional roles between carbon metabolism and the hrp system in rice pathogen Xanthomonas oryzae pv. oryzicola. PloS one. 2012; 7(2):e31855. doi: 10.1371/journal.pone.0031855. [PMID: 22384086]
  • Siham Yasari, Denis Prud'homme, Frédérique Tesson, Marek Jankowski, Jolanta Gutkowska, Emile Levy, Jean-Marc Lavoie. Effects of exercise training on molecular markers of lipogenesis and lipid partitioning in fructose-induced liver fat accumulation. Journal of nutrition and metabolism. 2012; 2012(?):181687. doi: 10.1155/2012/181687. [PMID: 21860785]
  • Sevki Adem, Mehmet Ciftci. Purification of rat kidney glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase enzymes using 2',5'-ADP Sepharose 4B affinity in a single chromatography step. Protein expression and purification. 2012 Jan; 81(1):1-4. doi: 10.1016/j.pep.2011.08.031. [PMID: 21930213]
  • Agnieszka Korga, Jaroslaw Dudka, Franciszek Burdan, Justyna Sliwinska, Slawomir Mandziuk, Katarzyna Dawidek-Pietryka. The redox imbalance and the reduction of contractile protein content in rat hearts administered with L-thyroxine and Doxorubicin. Oxidative medicine and cellular longevity. 2012; 2012(?):681367. doi: 10.1155/2012/681367. [PMID: 22530076]
  • Huawu Jiang, Pingzhi Wu, Sheng Zhang, Chi Song, Yaping Chen, Meiru Li, Yongxia Jia, Xiaohua Fang, Fan Chen, Guojiang Wu. Global analysis of gene expression profiles in developing physic nut (Jatropha curcas L.) seeds. PloS one. 2012; 7(5):e36522. doi: 10.1371/journal.pone.0036522. [PMID: 22574177]
  • Marina Leterrier, Juan B Barroso, Raquel Valderrama, José M Palma, Francisco J Corpas. NADP-dependent isocitrate dehydrogenase from Arabidopsis roots contributes in the mechanism of defence against the nitro-oxidative stress induced by salinity. TheScientificWorldJournal. 2012; 2012(?):694740. doi: 10.1100/2012/694740. [PMID: 22649311]
  • Emily B Merewitz, Thomas Gianfagna, Bingru Huang. Protein accumulation in leaves and roots associated with improved drought tolerance in creeping bentgrass expressing an ipt gene for cytokinin synthesis. Journal of experimental botany. 2011 Nov; 62(15):5311-33. doi: 10.1093/jxb/err166. [PMID: 21831843]
  • Yunliu Zeng, Zhiyong Pan, Yuduan Ding, Andan Zhu, Hongbo Cao, Qiang Xu, Xiuxin Deng. A proteomic analysis of the chromoplasts isolated from sweet orange fruits [Citrus sinensis (L.) Osbeck]. Journal of experimental botany. 2011 Nov; 62(15):5297-309. doi: 10.1093/jxb/err140. [PMID: 21841170]
  • Takashi Osanai, Akira Oikawa, Miyuki Azuma, Kan Tanaka, Kazuki Saito, Masami Yokota Hirai, Masahiko Ikeuchi. Genetic engineering of group 2 sigma factor SigE widely activates expressions of sugar catabolic genes in Synechocystis species PCC 6803. The Journal of biological chemistry. 2011 Sep; 286(35):30962-30971. doi: 10.1074/jbc.m111.231183. [PMID: 21757761]
  • Ozgür Fırat, Hikmet Y Cogun, Tüzin A Yüzereroğlu, Gülbin Gök, Ozge Fırat, Ferit Kargin, Yasemin Kötemen. A comparative study on the effects of a pesticide (cypermethrin) and two metals (copper, lead) to serum biochemistry of Nile tilapia, Oreochromis niloticus. Fish physiology and biochemistry. 2011 Sep; 37(3):657-66. doi: 10.1007/s10695-011-9466-3. [PMID: 21229307]
  • Gaik Chin Yap, Kok Keong Chee, Pei-Ying Hong, Christophe Lay, Cahya D Satria, Sumadiono, Yati Soenarto, Ekawaty L Haksari, Marion Aw, Lynette Pei-Chi Shek, Kaw Yan Chua, Yudong Zhao, Doreen Leow, Bee Wah Lee. Evaluation of stool microbiota signatures in two cohorts of Asian (Singapore and Indonesia) newborns at risk of atopy. BMC microbiology. 2011 Aug; 11(?):193. doi: 10.1186/1471-2180-11-193. [PMID: 21875444]
  • Ha-Neul Choi, Yong-Hyun Park, Ji-Hye Kim, Min-Jung Kang, Soo-Mi Jeong, Hyeon Hoe Kim, Jung-In Kim. Renoprotective and antioxidant effects of Saururus chinensis Baill in rats fed a high-fructose diet. Nutrition research and practice. 2011 Aug; 5(4):365-9. doi: 10.4162/nrp.2011.5.4.365. [PMID: 21994532]
  • Osbaldo Resendis-Antonio, Magdalena Hernández, Emmanuel Salazar, Sandra Contreras, Gabriel Martínez Batallar, Yolanda Mora, Sergio Encarnación. Systems biology of bacterial nitrogen fixation: high-throughput technology and its integrative description with constraint-based modeling. BMC systems biology. 2011 Jul; 5(?):120. doi: 10.1186/1752-0509-5-120. [PMID: 21801415]
  • Alejandro Tovar-Méndez, Manuel A Matamoros, Pilar Bustos-Sanmamed, Karl-Josef Dietz, Francisco Javier Cejudo, Nicolas Rouhier, Shusei Sato, Satoshi Tabata, Manuel Becana. Peroxiredoxins and NADPH-dependent thioredoxin systems in the model legume Lotus japonicus. Plant physiology. 2011 Jul; 156(3):1535-47. doi: 10.1104/pp.111.177196. [PMID: 21562331]
  • Manuela Cardi, Kamel Chibani, Donata Cafasso, Nicolas Rouhier, Jean-Pierre Jacquot, Sergio Esposito. Abscisic acid effects on activity and expression of barley (Hordeum vulgare) plastidial glucose-6-phosphate dehydrogenase. Journal of experimental botany. 2011 Jul; 62(11):4013-23. doi: 10.1093/jxb/err100. [PMID: 21464159]
  • Tanja Meyer, Christian Hölscher, Christian Schwöppe, Antje von Schaewen. Alternative targeting of Arabidopsis plastidic glucose-6-phosphate dehydrogenase G6PD1 involves cysteine-dependent interaction with G6PD4 in the cytosol. The Plant journal : for cell and molecular biology. 2011 Jun; 66(5):745-58. doi: 10.1111/j.1365-313x.2011.04535.x. [PMID: 21309870]
  • Jeffrey P Hill, Matthew J Germino, Deborah A Alongi. Carbon-use efficiency in green sinks is increased when a blend of apoplastic fructose and glucose is available for uptake. Journal of experimental botany. 2011 Mar; 62(6):2013-22. doi: 10.1093/jxb/erq407. [PMID: 21350040]
  • Kamal A Amin, Hamdy H Kamel, Mohamed A Abd Eltawab. Protective effect of Garcinia against renal oxidative stress and biomarkers induced by high fat and sucrose diet. Lipids in health and disease. 2011 Jan; 10(?):6. doi: 10.1186/1476-511x-10-6. [PMID: 21235803]
  • Anthony J Zera, Susan Newman, David Berkheim, Christine Black, Lindsay Klug, Erica Crone. Purification and characterization of cytoplasmic NADP+-isocitrate dehydrogenase, and amplification of the NADP+-IDH gene from the wing-dimorphic sand field cricket, Gryllus firmus. Journal of insect science (Online). 2011; 11(?):53. doi: 10.1673/031.011.5301. [PMID: 21861657]
  • Juan M Sandoval, Felipe A Arenas, Claudio C Vásquez. Glucose-6-phosphate dehydrogenase protects Escherichia coli from tellurite-mediated oxidative stress. PloS one. 2011; 6(9):e25573. doi: 10.1371/journal.pone.0025573. [PMID: 21984934]
  • Lars Matthias Voll, Robin Jonathan Horst, Anna-Maria Voitsik, Doreen Zajic, Birgit Samans, Jörn Pons-Kühnemann, Gunther Doehlemann, Steffen Münch, Ramon Wahl, Alexandra Molitor, Jörg Hofmann, Alfred Schmiedl, Frank Waller, Holger Bruno Deising, Regine Kahmann, Jörg Kämper, Karl-Heinz Kogel, Uwe Sonnewald. Common Motifs in the Response of Cereal Primary Metabolism to Fungal Pathogens are not Based on Similar Transcriptional Reprogramming. Frontiers in plant science. 2011; 2(?):39. doi: 10.3389/fpls.2011.00039. [PMID: 22645534]
  • Navneet Kaur, Jianping Hu. Defining the plant peroxisomal proteome: from Arabidopsis to rice. Frontiers in plant science. 2011; 2(?):103. doi: 10.3389/fpls.2011.00103. [PMID: 22645559]
  • Linkun Wu, Haibin Wang, Zhixing Zhang, Rui Lin, Zhongyi Zhang, Wenxiong Lin. Comparative metaproteomic analysis on consecutively Rehmannia glutinosa-monocultured rhizosphere soil. PloS one. 2011; 6(5):e20611. doi: 10.1371/journal.pone.0020611. [PMID: 21655235]
  • France Denoeud, Michaël Roussel, Benjamin Noel, Ivan Wawrzyniak, Corinne Da Silva, Marie Diogon, Eric Viscogliosi, Céline Brochier-Armanet, Arnaud Couloux, Julie Poulain, Béatrice Segurens, Véronique Anthouard, Catherine Texier, Nicolas Blot, Philippe Poirier, Geok Choo Ng, Kevin S W Tan, François Artiguenave, Olivier Jaillon, Jean-Marc Aury, Frédéric Delbac, Patrick Wincker, Christian P Vivarès, Hicham El Alaoui. Genome sequence of the stramenopile Blastocystis, a human anaerobic parasite. Genome biology. 2011; 12(3):R29. doi: 10.1186/gb-2011-12-3-r29. [PMID: 21439036]
  • Barbara Egli, Katharina Kölling, Claudia Köhler, Samuel C Zeeman, Sebastian Streb. Loss of cytosolic phosphoglucomutase compromises gametophyte development in Arabidopsis. Plant physiology. 2010 Dec; 154(4):1659-71. doi: 10.1104/pp.110.165027. [PMID: 20959421]
  • Cimen Karasu. Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment. The open cardiovascular medicine journal. 2010 Nov; 4(?):240-56. doi: 10.2174/1874192401004010240. [PMID: 21270942]
  • Yasumasa Okazaki, Mohammad Iqbal, Norito Kawakami, Yorihiro Yamamoto, Shinya Toyokuni, Shigeru Okada. A beverage containing fermented black soybean ameliorates ferric nitrilotriacetate-induced renal oxidative damage in rats. Journal of clinical biochemistry and nutrition. 2010 Nov; 47(3):198-207. doi: 10.3164/jcbn.10-52. [PMID: 21103028]
  • Johanna M S Lemons, Xiao-Jiang Feng, Bryson D Bennett, Aster Legesse-Miller, Elizabeth L Johnson, Irene Raitman, Elizabeth A Pollina, Herschel A Rabitz, Joshua D Rabinowitz, Hilary A Coller. Quiescent fibroblasts exhibit high metabolic activity. PLoS biology. 2010 Oct; 8(10):e1000514. doi: 10.1371/journal.pbio.1000514. [PMID: 21049082]
  • Wei Xiong, Lixia Liu, Chao Wu, Chen Yang, Qingyu Wu. 13C-tracer and gas chromatography-mass spectrometry analyses reveal metabolic flux distribution in the oleaginous microalga Chlorella protothecoides. Plant physiology. 2010 Oct; 154(2):1001-11. doi: 10.1104/pp.110.158956. [PMID: 20720172]
  • Yonglan Yu, Haili Zhang, Guan Zhu. Plant-type trehalose synthetic pathway in cryptosporidium and some other apicomplexans. PloS one. 2010 Sep; 5(9):e12593. doi: 10.1371/journal.pone.0012593. [PMID: 20830297]
  • Hermann Geldermann, Stanislav Cepica, Antonin Stratil, Heinz Bartenschlager, Siegfried Preuss. Genome-wide mapping of quantitative trait loci for fatness, fat cell characteristics and fat metabolism in three porcine F2 crosses. Genetics, selection, evolution : GSE. 2010 Jul; 42(?):31. doi: 10.1186/1297-9686-42-31. [PMID: 20667088]
  • Ana P Alonso, Rebecca J Piasecki, Yan Wang, Russell W LaClair, Yair Shachar-Hill. Quantifying the labeling and the levels of plant cell wall precursors using ion chromatography tandem mass spectrometry. Plant physiology. 2010 Jul; 153(3):915-24. doi: 10.1104/pp.110.155713. [PMID: 20442274]
  • Corinna Brandsch, Tobias Schmidt, Diana Behn, Kristin Weisse, Andreas S Mueller, Gabriele I Stangl. Glutathione deficiency down-regulates hepatic lipogenesis in rats. Lipids in health and disease. 2010 May; 9(?):50. doi: 10.1186/1476-511x-9-50. [PMID: 20482862]
  • Szymon Jozefczuk, Sebastian Klie, Gareth Catchpole, Jedrzej Szymanski, Alvaro Cuadros-Inostroza, Dirk Steinhauser, Joachim Selbig, Lothar Willmitzer. Metabolomic and transcriptomic stress response of Escherichia coli. Molecular systems biology. 2010 May; 6(?):364. doi: 10.1038/msb.2010.18. [PMID: 20461071]
  • Martin Hajduch, Leonard B Hearne, Jan A Miernyk, Jill E Casteel, Trupti Joshi, Ganesh K Agrawal, Zhao Song, Mingyi Zhou, Dong Xu, Jay J Thelen. Systems analysis of seed filling in Arabidopsis: using general linear modeling to assess concordance of transcript and protein expression. Plant physiology. 2010 Apr; 152(4):2078-87. doi: 10.1104/pp.109.152413. [PMID: 20118269]
  • Xiao-Qian Hu, Yu-Ming Wang, Jing-Feng Wang, Yong Xue, Zhao-Jie Li, Koji Nagao, Teruyoshi Yanagita, Chang-Hu Xue. Dietary saponins of sea cucumber alleviate orotic acid-induced fatty liver in rats via PPARalpha and SREBP-1c signaling. Lipids in health and disease. 2010 Mar; 9(?):25. doi: 10.1186/1476-511x-9-25. [PMID: 20211032]
  • Katja Witzel, Annette Weidner, Giridara-Kumar Surabhi, Rajeev K Varshney, Gotthard Kunze, Gerhard H Buck-Sorlin, Andreas Börner, Hans-Peter Mock. Comparative analysis of the grain proteome fraction in barley genotypes with contrasting salinity tolerance during germination. Plant, cell & environment. 2010 Feb; 33(2):211-22. doi: 10.1111/j.1365-3040.2009.02071.x. [PMID: 19906151]
  • Sumei Zhao, Jing Wang, Xinlei Song, Xi Zhang, Changrong Ge, Shizheng Gao. Impact of dietary protein on lipid metabolism-related gene expression in porcine adipose tissue. Nutrition & metabolism. 2010 Jan; 7(?):6. doi: 10.1186/1743-7075-7-6. [PMID: 20205889]
  • Marijana Todorcević, Stanko Skugor, Aleksei Krasnov, Bente Ruyter. Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes. BMC genomics. 2010 Jan; 11(?):39. doi: 10.1186/1471-2164-11-39. [PMID: 20078893]
  • Annelies Peeters, Myriam Baes. Role of PPARα in Hepatic Carbohydrate Metabolism. PPAR research. 2010; 2010(?):. doi: 10.1155/2010/572405. [PMID: 20936117]
  • Nadav S Bar, Nicole Radde. Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model. BMC systems biology. 2009 Nov; 3(?):107. doi: 10.1186/1752-0509-3-107. [PMID: 19903354]
  • San-Xiong Fu, Hao Cheng, Cunkou Qi. Microarray analysis of gene expression in seeds of Brassica napus planted in Nanjing (altitude: 8.9 m), Xining (altitude: 2261.2 m) and Lhasa (altitude: 3658 m) with different oil content. Molecular biology reports. 2009 Nov; 36(8):2375-86. doi: 10.1007/s11033-009-9460-3. [PMID: 19219639]
  • Jedrzej Szymanski, Szymon Jozefczuk, Zoran Nikoloski, Joachim Selbig, Victoria Nikiforova, Gareth Catchpole, Lothar Willmitzer. Stability of metabolic correlations under changing environmental conditions in Escherichia coli--a systems approach. PloS one. 2009 Oct; 4(10):e7441. doi: 10.1371/journal.pone.0007441. [PMID: 19829699]
  • Eija Rintala, Mervi Toivari, Juha-Pekka Pitkänen, Marilyn G Wiebe, Laura Ruohonen, Merja Penttilä. Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. BMC genomics. 2009 Oct; 10(?):461. doi: 10.1186/1471-2164-10-461. [PMID: 19804647]
  • Wendy L Allan, Shawn M Clark, Gordon J Hoover, Barry J Shelp. Role of plant glyoxylate reductases during stress: a hypothesis. The Biochemical journal. 2009 Sep; 423(1):15-22. doi: 10.1042/bj20090826. [PMID: 19740079]
  • Juan Rodrigues, Jaime Charris, José Domínguez, Jorge Angel, Neira Gamboa. Modification of oxidative status in Plasmodium berghei-infected erythrocytes by E-2-chloro-8-methyl-3-[(4'-methoxy-1'-indanoyl)-2'-methyliden]-quinoline compared to chloroquine. Memorias do Instituto Oswaldo Cruz. 2009 Sep; 104(6):865-70. doi: 10.1590/s0074-02762009000600008. [PMID: 19876558]
  • Astrid Ratzinger, Nadine Riediger, Andreas von Tiedemann, Petr Karlovsky. Salicylic acid and salicylic acid glucoside in xylem sap of Brassica napus infected with Verticillium longisporum. Journal of plant research. 2009 Sep; 122(5):571-9. doi: 10.1007/s10265-009-0237-5. [PMID: 19449088]
  • Bhakti Prinsi, Alfredo S Negri, Paolo Pesaresi, Maurizio Cocucci, Luca Espen. Evaluation of protein pattern changes in roots and leaves of Zea mays plants in response to nitrate availability by two-dimensional gel electrophoresis analysis. BMC plant biology. 2009 Aug; 9(?):113. doi: 10.1186/1471-2229-9-113. [PMID: 19698183]
  • Verena Karsten, Sean R Murray, Jeremy Pike, Kimberly Troy, Martina Ittensohn, Manvel Kondradzhyan, K Brooks Low, David Bermudes. msbB deletion confers acute sensitivity to CO2 in Salmonella enterica serovar Typhimurium that can be suppressed by a loss-of-function mutation in zwf. BMC microbiology. 2009 Aug; 9(?):170. doi: 10.1186/1471-2180-9-170. [PMID: 19689794]
  • Ipsita Pal Bhowmick, Nirbhay Kumar, Shobhona Sharma, Isabelle Coppens, Gotam K Jarori. Plasmodium falciparum enolase: stage-specific expression and sub-cellular localization. Malaria journal. 2009 Jul; 8(?):179. doi: 10.1186/1475-2875-8-179. [PMID: 19642995]
  • Juan R Rodrigues, Neira D Gamboa. Effect of dequalinium on the oxidative stress in Plasmodium berghei-infected erythrocytes. Parasitology research. 2009 Jun; 104(6):1491-6. doi: 10.1007/s00436-009-1355-7. [PMID: 19205739]
  • Sachin Kumar, Amita Mohan, Harindra S Balyan, Pushpendra K Gupta. Orthology between genomes of Brachypodium, wheat and rice. BMC research notes. 2009 May; 2(?):93. doi: 10.1186/1756-0500-2-93. [PMID: 19470185]
  • Christopher J Alteri, Sara N Smith, Harry L T Mobley. Fitness of Escherichia coli during urinary tract infection requires gluconeogenesis and the TCA cycle. PLoS pathogens. 2009 May; 5(5):e1000448. doi: 10.1371/journal.ppat.1000448. [PMID: 19478872]
  • Yoko Takahashi, Tseye-Oidov Odbayar, Takashi Ide. A comparative analysis of genistein and daidzein in affecting lipid metabolism in rat liver. Journal of clinical biochemistry and nutrition. 2009 May; 44(3):223-30. doi: 10.3164/jcbn.08-211. [PMID: 19430610]
  • Sandra Thibivilliers, Trupti Joshi, Kimberly B Campbell, Brian Scheffler, Dong Xu, Bret Cooper, Henry T Nguyen, Gary Stacey. Generation of Phaseolus vulgaris ESTs and investigation of their regulation upon Uromyces appendiculatus infection. BMC plant biology. 2009 Apr; 9(?):46. doi: 10.1186/1471-2229-9-46. [PMID: 19397807]
  • Rosa M Mateos, Daniel Bonilla-Valverde, Luis A del Río, José M Palma, Francisco J Corpas. NADP-dehydrogenases from pepper fruits: effect of maturation. Physiologia plantarum. 2009 Feb; 135(2):130-9. doi: 10.1111/j.1399-3054.2008.01179.x. [PMID: 19055545]
  • Katja Witzel, Annette Weidner, Giridara-Kumar Surabhi, Andreas Börner, Hans-Peter Mock. Salt stress-induced alterations in the root proteome of barley genotypes with contrasting response towards salinity. Journal of experimental botany. 2009; 60(12):3545-57. doi: 10.1093/jxb/erp198. [PMID: 19671579]
  • Boryana S Stamova, Debbie Laudencia-Chingcuanco, Diane M Beckles. Transcriptomic analysis of starch biosynthesis in the developing grain of hexaploid wheat. International journal of plant genomics. 2009; 2009(?):407426. doi: 10.1155/2009/407426. [PMID: 20224818]
  • Catherine-Ines Kolditz, Gilles Paboeuf, Maïena Borthaire, Diane Esquerré, Magali SanCristobal, Florence Lefèvre, Françoise Médale. Changes induced by dietary energy intake and divergent selection for muscle fat content in rainbow trout (Oncorhynchus mykiss), assessed by transcriptome and proteome analysis of the liver. BMC genomics. 2008 Oct; 9(?):506. doi: 10.1186/1471-2164-9-506. [PMID: 18959775]
  • Luis A Leyva, Yoav Bashan. Activity of two catabolic enzymes of the phosphogluconate pathway in mesquite roots inoculated with Azospirillum brasilense Cd. Plant physiology and biochemistry : PPB. 2008 Oct; 46(10):898-904. doi: 10.1016/j.plaphy.2008.05.011. [PMID: 18619846]
  • Yuling Yin, Hiroshi Ashihara. Expression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase isoform genes in suspension-cultured Arabidopsis thaliana cells. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2008 Sep; 63(9-10):713-20. doi: 10.1515/znc-2008-9-1017. [PMID: 19040112]
  • Shinichiro Maruyama, Kazuharu Misawa, Mineo Iseki, Masakatsu Watanabe, Hisayoshi Nozaki. Origins of a cyanobacterial 6-phosphogluconate dehydrogenase in plastid-lacking eukaryotes. BMC evolutionary biology. 2008 May; 8(?):151. doi: 10.1186/1471-2148-8-151. [PMID: 18485228]
  • Frances M Dupont. Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. BMC plant biology. 2008 Apr; 8(?):39. doi: 10.1186/1471-2229-8-39. [PMID: 18419817]
  • Paolo Bagnaresi, Anna Moschella, Ottavio Beretta, Federico Vitulli, Paolo Ranalli, Pierdomenico Perata. Heterologous microarray experiments allow the identification of the early events associated with potato tuber cold sweetening. BMC genomics. 2008 Apr; 9(?):176. doi: 10.1186/1471-2164-9-176. [PMID: 18416834]
  • A A F B V José, M A S Gama, D D P Lanna. Effects of trans-10, cis-12 conjugated linoleic acid on gene expression and lipid metabolism of adipose tissue of growing pigs. Genetics and molecular research : GMR. 2008 Apr; 7(2):284-94. doi: 10.4238/vol7-2gmr417. [PMID: 18551394]
  • Jeffrey P Simpson, Rosa Di Leo, Preetinder K Dhanoa, Wendy L Allan, Amina Makhmoudova, Shawn M Clark, Gordon J Hoover, Robert T Mullen, Barry J Shelp. Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification. Journal of experimental botany. 2008; 59(9):2545-54. doi: 10.1093/jxb/ern123. [PMID: 18495639]
  • Sally L Dillon, Frances M Shapter, Robert J Henry, Giovanni Cordeiro, Liz Izquierdo, L Slade Lee. Domestication to crop improvement: genetic resources for Sorghum and Saccharum (Andropogoneae). Annals of botany. 2007 Nov; 100(5):975-89. doi: 10.1093/aob/mcm192. [PMID: 17766842]
  • N P Goncharov, E Ia Kondratenko, S V Bannikova, A A Konovalov, K A Golovnina. [Comparative genetic analysis of diploid naked wheat Triticum sinskajae and the progenitor T. monococcum accession]. Genetika. 2007 Nov; 43(11):1491-500. doi: ". [PMID: 18186188]
  • Willem A Man In 't Veld, Francine Govers, Harold J G Meijer. Correlation of isozyme profiles with genomic sequences of Phytophthora ramorum and its P. sojae orthologues. Current genetics. 2007 Nov; 52(5-6):247-57. doi: 10.1007/s00294-007-0160-z. [PMID: 17968548]
  • Ia Iu Sharypina, V N Popov, V V Kirichenko. [Analysis of linkage between genes controlling enzymes in sunflower]. Genetika. 2007 Nov; 43(11):1486-90. doi: ". [PMID: 18186187]
  • R Panneerselvam, C Abdul Jaleel, R Somasundaram, R Sridharan, M Gomathinayagam. Carbohydrate metabolism in Dioscorea esculenta (Lour.) Burk. tubers and Curcuma longa L. rhizomes during two phases of dormancy. Colloids and surfaces. B, Biointerfaces. 2007 Sep; 59(1):59-66. doi: 10.1016/j.colsurfb.2007.04.006. [PMID: 17531451]
  • Amanda Aparecida Hayashi, Sérgio Raposo de Medeiros, Marina Hojaij Carvalho, Dante Pazzanese Duarte Lanna. Conjugated linoleic acid (CLA) effects on pups growth, milk composition and lipogenic enzymes in lactating rats. The Journal of dairy research. 2007 May; 74(2):160-6. doi: 10.1017/s002202990600224x. [PMID: 17291385]
  • Galip Guz, Billur Demirogullari, Nuray N Ulusu, Cihangir Dogu, Arzu Demirtola, Mustafa Kavutcu, Suna Omeroglu, Milan Stefek, Cimen Karasu. Stobadine protects rat kidney against ischaemia/reperfusion injury. Clinical and experimental pharmacology & physiology. 2007 Mar; 34(3):210-6. doi: 10.1111/j.1440-1681.2007.04574.x. [PMID: 17250641]
  • Daniel Marino, Esther M González, Pierre Frendo, Alain Puppo, Cesar Arrese-Igor. NADPH recycling systems in oxidative stressed pea nodules: a key role for the NADP+ -dependent isocitrate dehydrogenase. Planta. 2007 Jan; 225(2):413-21. doi: 10.1007/s00425-006-0354-5. [PMID: 16896792]
  • G Guz, E Oz, N Lortlar, N N Ulusu, N Nurlu, B Demirogullari, S Omeroglu, S Sert, C Karasu. The effect of taurine on renal ischemia/reperfusion injury. Amino acids. 2007; 32(3):405-11. doi: 10.1007/s00726-006-0383-1. [PMID: 17006602]
  • Tomasz Sledzinski, Anna Nogalska, Areta Hebanowska, Jerzy Klimek, Julian Swierczynski. Gender- and age-related changes in 6-phosphogluconate dehydrogenase gene expression in white adipose tissue of rats (Rattus norvegicus) are not related to serum testosterone concentration. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2006 May; 144(1):70-6. doi: 10.1016/j.cbpb.2006.01.009. [PMID: 16492403]
  • György Vas, Karina Conkrite, Wendy Amidon, Yueming Qian, Katalin Bánki, András Perl. Study of transaldolase deficiency in urine samples by capillary LC-MS/MS. Journal of mass spectrometry : JMS. 2006 Apr; 41(4):463-9. doi: 10.1002/jms.1004. [PMID: 16470722]
  • T Subramanian Kavitha, C Parthasarathy, R Sivakumar, R Badrinarayanan, K Balasubramanian. Effects of excess corticosterone on NADPH generating enzymes and glucose oxidation in Leydig cells of adult rats. Human & experimental toxicology. 2006 Mar; 25(3):119-25. doi: 10.1191/0960327106ht591oa. [PMID: 16634330]
  • H Ramazan Yilmaz, Esref Yuksel. Effect of 2,4-dichlorophenoxyacetic acid on the activities of some metabolic enzymes for generating pyridine nucleotide pool of cells from mouse liver. Toxicology and industrial health. 2005 Oct; 21(9):231-7. doi: 10.1191/0748233705th231oa. [PMID: 16342474]
  • Takashi Higashi, Misato Urai, Masato Taguchi, Yukiya Hashimoto. Mechanism responsible for the decreased hepatic NADPH generation rate in rats with bilateral ureter ligation-induced renal failure. Biological & pharmaceutical bulletin. 2005 Sep; 28(9):1809-12. doi: 10.1248/bpb.28.1809. [PMID: 16141568]
  • Ji-Biao Huang, Jimmy Espinoza, Roberto Romero, Howard R Petty. Transaldolase is part of a supramolecular complex containing glucose-6-phosphate dehydrogenase in human neutrophils that undergoes retrograde trafficking during pregnancy. Metabolism: clinical and experimental. 2005 Aug; 54(8):1027-33. doi: 10.1016/j.metabol.2005.03.005. [PMID: 16092052]
  • Amrisha Verma, Sulagna Basu, Sujata Ghosh, S Majumdar, N K Ganguly. The effect of type-1 fimbrial immunization on gut pathophysiological response in rats infected with Salmonella enterica subsp. enterica serovar Typhimurium. Molecular and cellular biochemistry. 2005 May; 273(1-2):127-35. doi: 10.1007/s11010-005-8160-0. [PMID: 16013447]
  • L L Dilworth, F O Omoruyi, O R Simon, E Y St A Morrison, H N Asemota. The effect of phytic acid on the levels of blood glucose and some enzymes of carbohydrate and lipid metabolism. The West Indian medical journal. 2005 Mar; 54(2):102-6. doi: 10.1590/s0043-31442005000200003. [PMID: 15999878]
  • S I Yurenkova, S V Kubrak, V V Titok, L V Khotyljova. [Flax species polymorphism for isozyme and metabolic markers]. Genetika. 2005 Mar; 41(3):334-40. doi: ". [PMID: 15865288]
  • Jérôme Delplanque, Ghislain Delpierre, Fred R Opperdoes, Emile Van Schaftingen. Tissue distribution and evolution of fructosamine 3-kinase and fructosamine 3-kinase-related protein. The Journal of biological chemistry. 2004 Nov; 279(45):46606-13. doi: 10.1074/jbc.m407678200. [PMID: 15331600]
  • Govind Keshri, Malini Bajpai, Vijai Lakshmi, Bachu Sreenivasulu Setty, Gopal Gupta. Role of energy metabolism in the pregnancy interceptive action of Ferula assafoetida and Melia azedarach extracts in rat. Contraception. 2004 Nov; 70(5):429-32. doi: 10.1016/j.contraception.2004.06.003. [PMID: 15504384]
  • Justyna Korczynska, Ewa Stelmanska, Anna Nogalska, Marek Szolkiewicz, Elzbieta Goyke, Julian Swierczynski, Boleslaw Rutkowski. Upregulation of lipogenic enzymes genes expression in white adipose tissue of rats with chronic renal failure is associated with higher level of sterol regulatory element binding protein-1. Metabolism: clinical and experimental. 2004 Aug; 53(8):1060-5. doi: 10.1016/j.metabol.2004.02.015. [PMID: 15281019]
  • Andrei L Kindzelskii, Tatsuya Ueki, Hitoshi Michibata, Tinnakorn Chaiworapongsa, Roberto Romero, Howard R Petty. 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy. Journal of immunology (Baltimore, Md. : 1950). 2004 May; 172(10):6373-81. doi: 10.4049/jimmunol.172.10.6373. [PMID: 15128828]
  • Mohammad Alamgir Hossain, Osamu Yamato, Masahiro Yamasaki, Yoshimitsu Maede. Inhibitory effect of pyrimidine and purine nucleotides on the multiplication of Babesia gibsoni: possible cause of low parasitemia and simultaneous reticulocytosis in canine babesiosis. The Journal of veterinary medical science. 2004 Apr; 66(4):389-95. doi: 10.1292/jvms.66.389. [PMID: 15133268]
  • Phillip M Debnam, Alisdair R Fernie, Andrea Leisse, Alison Golding, Caroline G Bowsher, Caroline Grimshaw, Jacqueline S Knight, Michael J Emes. Altered activity of the P2 isoform of plastidic glucose 6-phosphate dehydrogenase in tobacco (Nicotiana tabacum cv. Samsun) causes changes in carbohydrate metabolism and response to oxidative stress in leaves. The Plant journal : for cell and molecular biology. 2004 Apr; 38(1):49-59. doi: 10.1111/j.1365-313x.2004.02017.x. [PMID: 15053759]
  • Holly A Weber, Maureen Joseph. [Extraction and HPLC analysis of alkaloids in goldenseal]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 2004 Mar; 20(2):306-8. doi: . [PMID: 15969129]
  • Aglaia Pappa, Tia Estey, Rizwan Manzer, Donald Brown, Vasilis Vasiliou. Human aldehyde dehydrogenase 3A1 (ALDH3A1): biochemical characterization and immunohistochemical localization in the cornea. The Biochemical journal. 2003 Dec; 376(Pt 3):615-23. doi: 10.1042/bj20030810. [PMID: 12943535]