4-Nitrophenyl phosphate (BioDeep_00000003410)
Secondary id: BioDeep_00001868459
natural product human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C6H6NO6P (218.9933)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 17.92%
分子结构信息
SMILES: C1=CC(=CC=C1[N+](=O)[O-])OP(=O)(O)O
InChI: InChI=1S/C6H6NO6P/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12/h1-4H,(H2,10,11,12)
描述信息
4-Nitrophenyl phosphate, also known as nitrophenylphosphoric acid, belongs to the class of organic compounds known as phenyl phosphates. These are aromatic organooxygen compounds containing a phosphate group, which is O-esterified with a phenyl group. These are compounds containing a nitrophenol moiety, which consists of a benzene ring bearing both an hydroxyl group and a nitro group on two different ring carbon atoms.
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D002863 - Chromogenic Compounds
Acquisition and generation of the data is financially supported in part by CREST/JST.
D004396 - Coloring Agents
KEIO_ID N011
同义名列表
24 个代谢物同义名
p-Nitrophenyl phosphate bis(cyclohexylammonium) salt; 4-Nitrophenyl phosphate disodium salt hexahydrate; Phosphoric acid, mono(p-nitrophenyl) ester; Phosphoric acid, mono(4-nitrophenyl) ester; p-Nitrophenyl dihydrogen phosphoric acid; Phosphate, mono(p-nitrophenyl) ester; Phosphate, mono(4-nitrophenyl) ester; p-Nitrophenyl dihydrogen phosphate; Dipotassium nitrophenylphosphate; Diammonium nitrophenylphosphate; Monosodium nitrophenylphosphate; Magnesium nitrophenylphosphate; 4-Nitrophenyl phosphoric acid; p-Nitrophenyl phosphoric acid; Disodium nitrophenylphosphate; Sodium nitrophenylphosphate; Nitrophenylphosphoric acid; p-Nitrophenol phosphate; p-Nitrophenyl phosphate; 4-nitrophenyl phosphate; 4-Nitrophenylphosphate; Nitrophenylphosphate; PNPP; 4-Nitrophenyl phosphate
数据库引用编号
44 个数据库交叉引用编号
- ChEBI: CHEBI:17440
- KEGG: C03360
- PubChem: 378
- HMDB: HMDB0060272
- Metlin: METLIN6144
- DrugBank: DB04214
- ChEMBL: CHEMBL24231
- Wikipedia: Para-Nitrophenylphosphate
- MetaCyc: CPD-194
- CAS: 12778-12-0
- CAS: 330-13-2
- MoNA: KO001512
- MoNA: PS032603
- MoNA: PS070402
- MoNA: PS070410
- MoNA: PS032602
- MoNA: PS032607
- MoNA: PS070407
- MoNA: KO001514
- MoNA: KO001513
- MoNA: PS070403
- MoNA: PS032610
- MoNA: PS032605
- MoNA: PS032608
- MoNA: KO001511
- MoNA: PR100750
- MoNA: PS070401
- MoNA: PS070409
- MoNA: PR100600
- MoNA: PS070408
- MoNA: PR100193
- MoNA: KO001510
- MoNA: PS070404
- MoNA: PS032601
- MoNA: PS032604
- MoNA: PS032609
- MoNA: PR100599
- PMhub: MS000009630
- PubChem: 6198
- PDB-CCD: 4NP
- NIKKAJI: J32.922C
- RefMet: 4-Nitrophenyl phosphate
- KNApSAcK: 17440
- LOTUS: LTS0219314
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
10 个相关的物种来源信息
- 7711 - Chordata: LTS0219314
- 2759 - Eukaryota: LTS0219314
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 40674 - Mammalia: LTS0219314
- 33208 - Metazoa: LTS0219314
- 10066 - Muridae: LTS0219314
- 10088 - Mus: LTS0219314
- 10090 - Mus musculus: LTS0219314
- 10090 - Mus musculus: NA
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
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. [PMID: 21190107] - Henko Tadema, Cees G M Kallenberg, Coen A Stegeman, Peter Heeringa. Reactivity against complementary proteinase-3 is not increased in patients with PR3-ANCA-associated vasculitis.
PloS one.
2011 Mar; 6(3):e17972. doi:
10.1371/journal.pone.0017972
. [PMID: 21437233] - Adam V Wisnewski, Lan Xu, Eve Robinson, Jian Liu, Carrie A Redlich, Christina A Herrick. Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses.
Journal of occupational medicine and toxicology (London, England).
2011 Mar; 6(?):6. doi:
10.1186/1745-6673-6-6
. [PMID: 21414210] - Susana Morelli, Paola Scodelaro Bilbao, Sebastian Katz, Virginia Lezcano, Emilio Roldán, Ricardo Boland, Graciela Santillan. Protein phosphatases: possible bisphosphonate binding sites mediating stimulation of osteoblast proliferation.
Archives of biochemistry and biophysics.
2011 Mar; 507(2):248-53. doi:
10.1016/j.abb.2010.12.013
. [PMID: 21167123] - William P Halford, Ringo Püschel, Edward Gershburg, Andrew Wilber, Svetlana Gershburg, Brandon Rakowski. A live-attenuated HSV-2 ICP0 virus elicits 10 to 100 times greater protection against genital herpes than a glycoprotein D subunit vaccine.
PloS one.
2011 Mar; 6(3):e17748. doi:
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. [PMID: 21412438] - Laura K Erdman, Aggrey Dhabangi, Charles Musoke, Andrea L Conroy, Michael Hawkes, Sarah Higgins, Nimerta Rajwans, Kayla T Wolofsky, David L Streiner, W Conrad Liles, Christine M Cserti-Gazdewich, Kevin C Kain. Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study.
PloS one.
2011 Feb; 6(2):e17440. doi:
10.1371/journal.pone.0017440
. [PMID: 21364762] - Chao Ma, Yan Yao, Qing-Xi Yue, Xin-Wen Zhou, Peng-Yuan Yang, Wan-Ying Wu, Shu-Hong Guan, Bao-Hong Jiang, Min Yang, Xuan Liu, De-An Guo. Differential proteomic analysis of platelets suggested possible signal cascades network in platelets treated with salvianolic acid B.
PloS one.
2011 Feb; 6(2):e14692. doi:
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. [PMID: 21379382] - Tingsu Chen, Karolina Hoffmann, Sofia Ostman, Ann-Sofie Sandberg, Olof Olsson. Identification of gliadin-binding peptides by phage display.
BMC biotechnology.
2011 Feb; 11(?):16. doi:
10.1186/1472-6750-11-16
. [PMID: 21329494] - Giovanni Chaves-Bedoya, Fulgencio Espejel, Ricardo I Alcalá-Briseño, Juan Hernández-Vela, Laura Silva-Rosales. Short distance movement of genomic negative strands in a host and nonhost for Sugarcane mosaic virus (SCMV).
Virology journal.
2011 Jan; 8(?):15. doi:
10.1186/1743-422x-8-15
. [PMID: 21232133] - Cheng-qin Liang, Xiao-jian Su, Xian-li Zhou, Jiang-ke Qin, Qing Xu, Rong-gan Liang, Ming-po Zheng. [Studies on the chemical constituents of Rubus parvifolius].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2011 Jan; 34(1):64-6. doi:
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- Katherine Neubecker, Beverley Adams-Huet, Irfan M Farukhi, Rosinda C Delapena, Ugis Gruntmanis. Predictors of fracture risk and bone mineral density in men with prostate cancer on androgen deprivation therapy.
Journal of osteoporosis.
2011; 2011(?):924595. doi:
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. [PMID: 21826255] - Suvi Ruuskanen, Heli Siitari, Tapio Eeva, Eugen Belskii, Antero Järvinen, Anvar Kerimov, Indrikis Krams, Juan Moreno, Chiara Morosinotto, Raivo Mänd, Erich Möstl, Markku Orell, Anna Qvarnström, Juha-Pekka Salminen, Fred Slater, Vallo Tilgar, Marcel E Visser, Wolfgang Winkel, Herwig Zang, Toni Laaksonen. Geographical variation in egg mass and egg content in a passerine bird.
PloS one.
2011; 6(11):e25360. doi:
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. [PMID: 22110579] - Serap Turan, Burcu Topcu, İbrahim Gökçe, Tülay Güran, Zeynep Atay, Anjumanara Omar, Teoman Akçay, Abdullah Bereket. Serum alkaline phosphatase levels in healthy children and evaluation of alkaline phosphatase z-scores in different types of rickets.
Journal of clinical research in pediatric endocrinology.
2011; 3(1):7-11. doi:
10.4274/jcrpe.v3i1.02
. [PMID: 21448327] - Sebastian Kobold, Sinje Tams, Tim Luetkens, Yanran Cao, Orhan Sezer, Britta Marlen Bartels, Henrike Reinhard, Julia Templin, Katrin Bartels, York Hildebrandt, Nesrine Lajmi, Andreas Marx, Friedrich Haag, Carsten Bokemeyer, Nicolaus Kröger, Djordje Atanackovic. Patients with multiple myeloma develop SOX2-specific autoantibodies after allogeneic stem cell transplantation.
Clinical & developmental immunology.
2011; 2011(?):302145. doi:
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. [PMID: 22190969] - Subhra Karmakar, Sangita Majumdar, Anasuya Maiti, Monalisa Choudhury, Aniruddha Ghosh, Asankur S Das, Chandan Mitra. Protective Role of Black Tea Extract against Nonalcoholic Steatohepatitis-Induced Skeletal Dysfunction.
Journal of osteoporosis.
2011; 2011(?):426863. doi:
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. [PMID: 21772972] - Jo Ann Janovick, Byung S Park, P Michael Conn. Therapeutic rescue of misfolded mutants: validation of primary high throughput screens for identification of pharmacoperone drugs.
PloS one.
2011; 6(7):e22784. doi:
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. [PMID: 21818389] - Wai-Hong Wu, Elizabeth Gersch, Kihyuck Kwak, Subhashini Jagu, Balasubramanyam Karanam, Warner K Huh, Robert L Garcea, Richard B S Roden. Capsomer vaccines protect mice from vaginal challenge with human papillomavirus.
PloS one.
2011; 6(11):e27141. doi:
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. [PMID: 22069498] - Ryoma Nakao, Hideki Hasegawa, Kuniyasu Ochiai, Shogo Takashiba, Akira Ainai, Makoto Ohnishi, Haruo Watanabe, Hidenobu Senpuku. Outer membrane vesicles of Porphyromonas gingivalis elicit a mucosal immune response.
PloS one.
2011; 6(10):e26163. doi:
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. [PMID: 22022548] - Elena Veselkin, Maria Kondratyev, Yoav Lurie, Efrat Ron, Moshe Santo, Shimon Reif, Irma Elashvili, Lana Bar, Gerardo Z Lederkremer. A secreted form of the asialoglycoprotein receptor, sH2a, as a novel potential noninvasive marker for liver fibrosis.
PloS one.
2011; 6(11):e27210. doi:
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. [PMID: 22096539] - Jason W Ashley, Zhenqi Shi, Haibo Zhao, Xingsheng Li, Robert A Kesterson, Xu Feng. Genetic ablation of CD68 results in mice with increased bone and dysfunctional osteoclasts.
PloS one.
2011; 6(10):e25838. doi:
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. [PMID: 21991369] - Christian Radauer, Farzaneh Adhami, Irene Fürtler, Stefan Wagner, Dorothee Allwardt, Enrico Scala, Christof Ebner, Christine Hafner, Wolfgang Hemmer, Adriano Mari, Heimo Breiteneder. Latex-allergic patients sensitized to the major allergen hevein and hevein-like domains of class I chitinases show no increased frequency of latex-associated plant food allergy.
Molecular immunology.
2011 Jan; 48(4):600-9. doi:
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. [PMID: 21095007] - Yayoi Takeuchi, Michaela M Salcher, Masayuki Ushio, Rie Shimizu-Inatsugi, Masaki J Kobayashi, Bibian Diway, Christian von Mering, Jakob Pernthaler, Kentaro K Shimizu. In situ enzyme activity in the dissolved and particulate fraction of the fluid from four pitcher plant species of the genus Nepenthes.
PloS one.
2011; 6(9):e25144. doi:
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. [PMID: 21949872] - Giuliana López-Navarrete, Espiridión Ramos-Martínez, Karina Suárez-Álvarez, Jesús Aguirre-García, Yadira Ledezma-Soto, Sonia León-Cabrera, Marco Gudiño-Zayas, Carolina Guzmán, Gabriela Gutiérrez-Reyes, Joselín Hernández-Ruíz, Ignacio Camacho-Arroyo, Guillermo Robles-Díaz, David Kershenobich, Luis I Terrazas, Galileo Escobedo. Th2-associated alternative Kupffer cell activation promotes liver fibrosis without inducing local inflammation.
International journal of biological sciences.
2011; 7(9):1273-86. doi:
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. [PMID: 22110380] - Philippe Boeuf, Wina Hasang, Eric Hanssen, Jocelyn D Glazier, Stephen J Rogerson. Relevant assay to study the adhesion of Plasmodium falciparum-infected erythrocytes to the placental epithelium.
PloS one.
2011; 6(6):e21126. doi:
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. [PMID: 21731654] - Avishek Biswas, Jag Mohan, Kochigant Venkata Hanumant Sastry. Age-dependent variation in hormonal concentration and biochemical constituents in blood plasma of Indian native fowl.
Veterinary medicine international.
2010 Dec; 2010(?):737292. doi:
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. [PMID: 21234314] - Andrea L Conroy, Happy Phiri, Michael Hawkes, Simon Glover, Mac Mallewa, Karl B Seydel, Terrie E Taylor, Malcolm E Molyneux, Kevin C Kain. Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study.
PloS one.
2010 Dec; 5(12):e15291. doi:
10.1371/journal.pone.0015291
. [PMID: 21209923] - Hyun-Ja Jeong, In-Young Choi, Min-Ho Kim, Hyung-Min Kim, Phil-Dong Moon, Jin-Woo Hong, Soo-Hyun Kim. Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism.
Journal of neuroinflammation.
2010 Nov; 7(?):85. doi:
10.1186/1742-2094-7-85
. [PMID: 21108840] - Guillermo Suñé, Eduard Sarró, Marta Puigmulé, Joan López-Hellín, Madeleine Zufferey, Thomas Pertel, Jeremy Luban, Anna Meseguer. Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney.
PloS one.
2010 Nov; 5(11):e13930. doi:
10.1371/journal.pone.0013930
. [PMID: 21085665] - Lisa D Kalischuk, Frances Leggett, G Douglas Inglis. Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells.
Gut pathogens.
2010 Nov; 2(?):14. doi:
10.1186/1757-4749-2-14
. [PMID: 21040540] - Andrea Harrer, Roland Lang, Robert Grims, Michaela Braitsch, Thomas Hawranek, Werner Aberer, Lothar Vogel, Walther Schmid, Fatima Ferreira, Martin Himly. Diclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolites.
PloS one.
2010 Oct; 5(10):e13707. doi:
10.1371/journal.pone.0013707
. [PMID: 21060839] - Aude Deloumeau, Sophie Bayard, Quentin Coquerel, Pierre Déchelotte, Christine Bole-Feysot, Bertrand Carlander, Valérie Cochen De Cock, Sergueï O Fetissov, Yves Dauvilliers. Increased immune complexes of hypocretin autoantibodies in narcolepsy.
PloS one.
2010 Oct; 5(10):e13320. doi:
10.1371/journal.pone.0013320
. [PMID: 20967199] - Sheng Liu, Xiao-Yun Song, Chun-Yu Wu, Xiang-Hui Han, Ling-Lin Liu, Jian-Wen Liu, Yi-Chun Xu. [Effects of serum containing Fructus Cnidii and Psoralea corylifolia on highly metastatic human breast cancer cell line MDA-MB-231BO and bone marrow stromal cell line ST-2].
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2010 Sep; 8(9):877-82. doi:
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. [PMID: 20836979] - Sujoy Das, Sudipta Saha, Gopal Chandra Majumder, Sandhya Rekha Dungdung. Purification and characterization of a sperm motility inhibiting factor from caprine epididymal plasma.
PloS one.
2010 Aug; 5(8):e12039. doi:
10.1371/journal.pone.0012039
. [PMID: 20706623] - Yoshifumi Hashimoto, Sheng Zhang, Gary W Blissard. Ao38, a new cell line from eggs of the black witch moth, Ascalapha odorata (Lepidoptera: Noctuidae), is permissive for AcMNPV infection and produces high levels of recombinant proteins.
BMC biotechnology.
2010 07; 10(?):50. doi:
10.1186/1472-6750-10-50
. [PMID: 20602790] - Sergey A Trushin, Gary D Bren, Andrew D Badley. CXCR4 Tropic HIV-1 gp120 Inhibition of SDF-1α-Induced Chemotaxis Requires Lck and is Associated with Cofilin Phosphorylation.
The open virology journal.
2010 Jun; 4(?):157-62. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2010 Jun; 40(6):369-80. doi:
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. [PMID: 20297923] - Natalia Pitala, Heli Siitari, Lars Gustafsson, Jon E Brommer. Costs and benefits of experimentally induced changes in the allocation of growth versus immune function under differential exposure to ectoparasites.
PloS one.
2010 May; 5(5):e10814. doi:
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. [PMID: 20520832] - Corinna Brandsch, Tobias Schmidt, Diana Behn, Kristin Weisse, Andreas S Mueller, Gabriele I Stangl. Glutathione deficiency down-regulates hepatic lipogenesis in rats.
Lipids in health and disease.
2010 May; 9(?):50. doi:
10.1186/1476-511x-9-50
. [PMID: 20482862] - Jin Oshikawa, Norifumi Urao, Ha Won Kim, Nihal Kaplan, Masooma Razvi, Ronald McKinney, Leslie B Poole, Tohru Fukai, Masuko Ushio-Fukai. Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice.
PloS one.
2010 Apr; 5(4):e10189. doi:
10.1371/journal.pone.0010189
. [PMID: 20422004] - Irini Tossidou, Beina Teng, Jan Menne, Nelli Shushakova, Joon-Keun Park, Jan U Becker, Friedrich Modde, Michael Leitges, Hermann Haller, Mario Schiffer. Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.
PloS one.
2010 Apr; 5(4):e10185. doi:
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. [PMID: 20419132] - Eduardo M Clop, María A Perillo. Langmuir films from human placental membranes: preparation, rheology, transfer to alkylated glasses, and sigmoidal kinetics of alkaline phosphatase in the resultant Langmuir-Blodgett film.
Cell biochemistry and biophysics.
2010 Apr; 56(2-3):91-107. doi:
10.1007/s12013-009-9073-4
. [PMID: 20033626] - Maria A Trainer, David Capstick, Alicja Zachertowska, Kathy N Lam, Scott R D Clark, Trevor C Charles. Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti.
BMC microbiology.
2010 Mar; 10(?):92. doi:
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