o-Fluorobenzoate (BioDeep_00000003384)

 

Secondary id: BioDeep_00001868529


代谢物信息卡片


2-FLUOROBENZOIC ACID

化学式: C7H5FO2 (140.0274)
中文名称: 2-氟苯甲酸
谱图信息: 最多检出来源 Viridiplantae(plant) 8.99%

分子结构信息

SMILES: C1=CC=C(C(=C1)C(=O)O)F
InChI: InChI=1S/C7H5FO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)

描述信息

KEIO_ID F024

同义名列表

5 个代谢物同义名

2-FLUOROBENZOIC ACID; o-Fluorobenzoate; 2-Fluorobenzoate; 2-Fluorobenzoate; Benzoic acid, 2-fluoro-



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ANXA5, APOE, ATM, BCL2, CASP3, CDK2, DAO, EGFR, NEU2, NEU4, PCSK9, SH2D1A
Peripheral membrane protein 3 ACHE, ANXA5, DAO
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 4 BCL2, EGFR, FDFT1, NEU4
Mitochondrion membrane 1 NEU4
Nucleus 8 ACHE, APOE, ATM, BCL2, CASP3, CDK2, EGFR, PARP1
cytosol 9 ANXA5, ATM, BCL2, CASP3, CDK2, DAO, NEU2, PARP1, SH2D1A
dendrite 1 APOE
nuclear body 1 PARP1
centrosome 2 ATM, CDK2
nucleoplasm 4 ATM, CASP3, CDK2, PARP1
Cell membrane 5 ACHE, DAO, EGFR, GLP1R, ITGAM
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 2 FDFT1, GLP1R
Synapse 1 ACHE
cell junction 1 EGFR
cell surface 4 ACHE, EGFR, ITGAM, PCSK9
glutamatergic synapse 3 APOE, CASP3, EGFR
Golgi apparatus 3 ACHE, APOE, PCSK9
Golgi membrane 1 EGFR
lysosomal membrane 2 EGF, PCSK9
mitochondrial inner membrane 1 NEU4
neuromuscular junction 1 ACHE
neuronal cell body 2 APOE, CASP3
sarcolemma 1 ANXA5
Cytoplasm, cytosol 3 DAO, NEU2, PARP1
Lysosome 3 NEU2, NEU4, PCSK9
endosome 3 CDK2, EGFR, PCSK9
plasma membrane 10 ACHE, APOE, DAO, EGF, EGFR, GCG, GLP1R, ITGAM, NEU4, PCSK9
presynaptic active zone 1 DAO
Membrane 12 ACHE, ANXA5, APOE, BCL2, EGF, EGFR, FDFT1, GLP1R, ITGAM, NEU2, NEU4, PARP1
apical plasma membrane 1 EGFR
basolateral plasma membrane 1 EGFR
extracellular exosome 5 ANXA5, APOE, DAO, EGF, ITGAM
endoplasmic reticulum 4 APOE, BCL2, FDFT1, PCSK9
extracellular space 8 ACHE, APOE, DAO, EGF, EGFR, GCG, ITGAM, PCSK9
lysosomal lumen 1 NEU4
perinuclear region of cytoplasm 3 ACHE, EGFR, PCSK9
bicellular tight junction 1 DAO
mitochondrion 2 BCL2, PARP1
protein-containing complex 3 BCL2, EGFR, PARP1
intracellular membrane-bounded organelle 1 ATM
Microsome membrane 1 NEU4
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 EGFR, ITGAM
Secreted 5 ACHE, APOE, DAO, GCG, PCSK9
extracellular region 7 ACHE, ANXA5, APOE, DAO, EGF, GCG, PCSK9
Mitochondrion outer membrane 2 BCL2, NEU4
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, NEU4
Extracellular side 2 ACHE, DAO
transcription regulator complex 2 CDK2, PARP1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 2 ATM, CDK2
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, EGFR
external side of plasma membrane 2 ANXA5, ITGAM
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 1 APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 1 APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
cytoplasmic vesicle 1 ATM
nucleolus 2 ATM, PARP1
Early endosome 2 APOE, PCSK9
COPII-coated ER to Golgi transport vesicle 1 PCSK9
Membrane raft 2 EGFR, ITGAM
pore complex 1 BCL2
focal adhesion 2 ANXA5, EGFR
spindle 1 ATM
extracellular matrix 1 APOE
Peroxisome 1 DAO
basement membrane 1 ACHE
intracellular vesicle 1 EGFR
Peroxisome matrix 2 ATM, DAO
peroxisomal matrix 2 ATM, DAO
collagen-containing extracellular matrix 2 ANXA5, APOE
Late endosome 1 PCSK9
receptor complex 1 EGFR
Cell projection, neuron projection 1 NEU4
Zymogen granule membrane 1 ANXA5
neuron projection 1 NEU4
chromatin 1 PARP1
cell projection 1 DAO
Chromosome 1 PARP1
Secreted, extracellular space 2 APOE, DAO
Nucleus, nucleolus 1 PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 2 CDK2, PARP1
blood microparticle 1 APOE
Lipid-anchor, GPI-anchor 1 ACHE
site of double-strand break 2 ATM, PARP1
nuclear envelope 2 CDK2, PARP1
specific granule membrane 1 ITGAM
tertiary granule membrane 1 ITGAM
Melanosome 1 APOE
side of membrane 1 ACHE
myelin sheath 1 BCL2
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
plasma membrane raft 1 ITGAM
secretory granule lumen 1 GCG
endoplasmic reticulum lumen 3 APOE, GCG, PCSK9
male germ cell nucleus 1 CDK2
platelet alpha granule lumen 1 EGF
specific granule lumen 1 DAO
extrinsic component of synaptic vesicle membrane 1 ATM
Lysosome lumen 1 NEU4
vesicle membrane 1 ANXA5
clathrin-coated endocytic vesicle membrane 3 APOE, EGF, EGFR
Cajal body 1 CDK2
synaptic cleft 2 ACHE, APOE
protein-DNA complex 1 PARP1
endolysosome membrane 1 PCSK9
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 NEU4
condensed chromosome 1 CDK2
DNA repair complex 1 ATM
extrinsic component of external side of plasma membrane 1 PCSK9
Nucleus, Cajal body 1 CDK2
X chromosome 1 CDK2
Y chromosome 1 CDK2
site of DNA damage 1 PARP1
integrin complex 1 ITGAM
cyclin-dependent protein kinase holoenzyme complex 1 CDK2
discoidal high-density lipoprotein particle 1 APOE
cyclin E1-CDK2 complex 1 CDK2
cyclin E2-CDK2 complex 1 CDK2
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
endocytic vesicle lumen 1 APOE
PCSK9-LDLR complex 1 PCSK9
[Glucagon-like peptide 1]: Secreted 1 GCG
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
integrin alphaM-beta2 complex 1 ITGAM
catalytic complex 1 NEU2
PCSK9-AnxA2 complex 1 PCSK9
endothelial microparticle 1 ANXA5
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
BAD-BCL-2 complex 1 BCL2
cyclin A2-CDK2 complex 1 CDK2
[Isoform H]: Cell membrane 1 ACHE
cyclin A1-CDK2 complex 1 CDK2
[Isoform 2]: Mitochondrion inner membrane 1 NEU4
organelle inner membrane 1 NEU4


文献列表

  • Asiphe Fanele, Sizwe I Ndlovu. Endophytic fungal species Nigrospora oryzae and Alternaria alternata exhibit antimicrobial activity against gram-positive and gram-negative multi-drug resistant clinical bacterial isolates. BMC complementary medicine and therapies. 2023 Sep; 23(1):323. doi: 10.1186/s12906-023-04157-8. [PMID: 37715184]
  • Adam Badar, Sarah DeFreitas, James M McDonnell, Norhakim Yahya, David Thakor, Reza Razavi, Richard Smith, Steven Sacks, Gregory E D Mullen. Recombinant complement receptor 2 radiolabeled with [99mTc(CO)3]+: a potential new radiopharmaceutical for imaging activated complement. PloS one. 2011 Apr; 6(4):e18275. doi: 10.1371/journal.pone.0018275. [PMID: 21494666]
  • M Sakurai, M Ohsako, M Nagano, C Nakamura, O Tsuzuki, M Ichikawa, Y Matsumoto. [Effect of human serum albumin on transport of drugs through human erythrocyte membranes]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1996 Aug; 116(8):630-8. doi: 10.1248/yakushi1947.116.8_630. [PMID: 8831264]
  • R Miura. 19F-NMR study on the interaction of fluorobenzoate with porcine kidney D-amino acid oxidase. Journal of biochemistry. 1989 Feb; 105(2):318-22. doi: 10.1093/oxfordjournals.jbchem.a122660. [PMID: 2566599]