Jujuboside B (BioDeep_00000000274)

 

Secondary id: BioDeep_00000396392, BioDeep_00000620005, BioDeep_00001867484

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


2-[(4-{[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl]oxy}-5-hydroxy-2-{[16-hydroxy-2,6,6,10,16-pentamethyl-18-(2-methylprop-1-en-1-yl)-19,21-dioxahexacyclo[18.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰.0¹⁵,²⁰]tricosan-7-yl]oxy}oxan-3-yl)oxy]-6-methyloxane-3,4,5-triol

化学式: C52H84O21 (1044.5504814)
中文名称: 酸枣仁皂苷 B, 酸枣仁皂苷B1, 酸枣仁皂苷B, 酸枣仁皂苷 B1, 酸枣仁皂苷 B
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)=CC1CC(C)(O)C2C3CCC4C5(C)CCC(OC6OCC(O)C(OC7OC(CO)C(O)C(O)C7OC7OCC(O)C(O)C7O)C6OC6OC(C)C(O)C(O)C6O)C(C)(C)C5CCC4(C)C34COC2(C4)O1
InChI: InChI=1S/C52H84O21/c1-22(2)15-24-16-50(8,63)42-25-9-10-30-48(6)13-12-31(47(4,5)29(48)11-14-49(30,7)51(25)20-52(42,73-24)66-21-51)69-45-41(72-44-38(62)35(59)32(56)23(3)67-44)39(27(55)19-65-45)70-46-40(36(60)34(58)28(17-53)68-46)71-43-37(61)33(57)26(54)18-64-43/h15,23-46,53-63H,9-14,16-21H2,1-8H3

描述信息

Jujuboside B is a triterpenoid.
Jujuboside B is a natural product found in Ziziphus spina-christi, Ziziphus jujuba, and Hovenia dulcis with data available.
Jujuboside B1 is found in fruits. Jujuboside B1 is isolated from seeds of Zizyphus jujuba (Chinese date).
Isolated from seeds of Zizyphus jujuba (Chinese date). Jujuboside B1 is found in fruits.
Jujuboside B is one of the major bioactive constituents isolated from Zizyphus jujuba. Jujuboside B can inhibit platelet aggregation[1].
Jujuboside B is one of the major bioactive constituents isolated from Zizyphus jujuba. Jujuboside B can inhibit platelet aggregation[1].

同义名列表

5 个代谢物同义名

2-[(4-{[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl]oxy}-5-hydroxy-2-{[16-hydroxy-2,6,6,10,16-pentamethyl-18-(2-methylprop-1-en-1-yl)-19,21-dioxahexacyclo[18.2.1.0¹,¹⁴.0²,¹¹.0⁵,¹⁰.0¹⁵,²⁰]tricosan-7-yl]oxy}oxan-3-yl)oxy]-6-methyloxane-3,4,5-triol; Jujuboside B, >=98\\% (HPLC); Jujuboside B1; Jujuboside B; Jujuboside



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Wei Li, Yanqing Zhang, Jing Zhao, Tan Yang, Junbo Xie. L-carnitine modified nanoparticles target the OCTN2 transporter to improve the oral absorption of jujuboside B. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2024 Jan; ?(?):114185. doi: 10.1016/j.ejpb.2024.114185. [PMID: 38280469]
  • Jinrui Liu, Yanqing Zhang, Chang-Jiang-Sheng Lai, Junbo Xie. Multitarget Protective Effects of JUB on Aβ-Induced Neurotoxicity and the Mechanism Predication Using Network Pharmacology Analysis. Journal of agricultural and food chemistry. 2023 Dec; 71(51):20724-20734. doi: 10.1021/acs.jafc.3c06430. [PMID: 38098161]
  • Caijing Liu, Jing Li, Lidan Zhu, Linmin Lian, Luyi Jiang, Hanbing Li, Jizhong Yan, Chu Chu. A sensitive two-step stacking by coupling field-enhanced sample injection and micelle to cyclodextrin stacking for the determination of neutral analytes. Journal of chromatography. A. 2020 May; 1618(?):460854. doi: 10.1016/j.chroma.2020.460854. [PMID: 31980258]
  • Yan Chen, Enci Jiang, Jizhong Yan, Yi Tao. Validation of an analytical method using UPLC-MS/MS to quantify four bioactive components in rat plasma and its application to pharmacokinetic study of traditional and dispensing granules decoction of Ziziphi Spinosae Semen. Biomedical chromatography : BMC. 2020 Apr; 34(4):e4797. doi: 10.1002/bmc.4797. [PMID: 31989669]
  • Muhammad Noman Khan, Faraz Ul Haq, Saeedur Rahman, Arslan Ali, Syed Ghulam Musharraf. Metabolite distribution and correlation studies of Ziziphus jujuba and Ziziphus nummularia using LC-ESI-MS/MS. Journal of pharmaceutical and biomedical analysis. 2020 Jan; 178(?):112918. doi: 10.1016/j.jpba.2019.112918. [PMID: 31629227]
  • Chuan-Qin Wu, Guan-Hua Chen. Detection of synergistic effect of superoxide dismutase and jujubosides on scavenging superoxide anion radical by capillary electrophoresis. Biomedical chromatography : BMC. 2019 Oct; 33(10):e4630. doi: 10.1002/bmc.4630. [PMID: 31243785]
  • Prafull Bandopant Ninave, Savita Dattatray Patil. Antiasthmatic potential of Zizyphus jujuba Mill and Jujuboside B. - Possible role in the treatment of asthma. Respiratory physiology & neurobiology. 2019 02; 260(?):28-36. doi: 10.1016/j.resp.2018.12.001. [PMID: 30521862]
  • Yan Yan, Qiang Li, Chen-hui Du, Jin-ping Jia, Hong-xia Feng, Xue-mei Qin. [Investigation of the potentially effective components of Semen Ziziphi Spinosae based on “in vitro to in vivo” translation approach]. Yao xue xue bao = Acta pharmaceutica Sinica. 2017 Feb; 52(2):283-90. doi: NULL. [PMID: 29979520]
  • Yanqing Zhang, Yan Zhang, Kunsheng Zhang, Guijie Ma, Mingchun Zhang, Junbo Xie. Degradation kinetics of jujuboside b by rat intestinal flora in vitro with an RRLC-MS-MS method. Journal of chromatographic science. 2014 Aug; 52(7):691-6. doi: 10.1093/chromsci/bmt100. [PMID: 23828910]
  • Eun Ji Seo, So Young Lee, Sam Sik Kang, Yi-Sook Jung. Zizyphus jujuba and its active component jujuboside B inhibit platelet aggregation. Phytotherapy research : PTR. 2013 Jun; 27(6):829-34. doi: 10.1002/ptr.4809. [PMID: 22893618]
  • Mingchun Zhang, Yanqing Zhang, Junbo Xie. Simultaneous determination of jujuboside A, B and betulinic acid in semen Ziziphi spinosae by high performance liquid chromatography-evaporative light scattering detection. Journal of pharmaceutical and biomedical analysis. 2008 Dec; 48(5):1467-70. doi: 10.1016/j.jpba.2008.09.022. [PMID: 18977107]