Corilagin (BioDeep_00000002646)

   

human metabolite PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


(1S,19R,21S,22R,23R)-6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-2,17,20-trioxatetracyclo[17.3.1.0^{4,9}.0^{10,15}]tricosa-4,6,8,10,12,14-hexaen-21-yl 3,4,5-trihydroxybenzoate

化学式: C27H22O18 (634.0806112)
中文名称: 柯里拉京
谱图信息: 最多检出来源 Astragalus membranaceus(otcml) 1.38%

分子结构信息

SMILES: c1c(cc(c(c1O)O)O)C(=O)O[C@H]1[C@@H]([C@@H]2[C@@H]([C@@H](COC(=O)c3cc(c(c(c3c3c(cc(c(c3O)O)O)C(=O)O2)O)O)O)O1)O)O
InChI: InChI=1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2/t13-,19-,22-,23+,27+/m1/s1

描述信息

Corilagin is a member of the class of compounds known as ellagitannins, a class of hydrolyzable tannins. Hydrolyzable tannins are tannins with a structure characterized by either of the following models: (1) a structure containing galloyl units (in some cases, shikimic acid units) linked to diverse polyol carbohydrate, catechin, or triterpenoid units, or (2) a structure containing at least two galloyl units C-C coupled to each other and not containing a glycosidically linked catechin unit. Corilagin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Corilagin can be found in pomegranate, which makes corilagin a potential biomarker for the consumption of this food product. Corilagin was first isolated in 1951 from Dividivi extract and from Caesalpinia coriaria, hence the name of the molecule. It can also be found in Alchornea glandulosa and in the leaves of Punica granatum (pomegranate) (Wikipedia). Corilagin has been shown to exhibit thrombolytic function (PMID: 14750026).
Corilagin is an ellagitannin with a hexahydroxydiphenoyl group bridging over the 3-O and 6-O of the glucose core. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a non-steroidal anti-inflammatory drug and an antioxidant. It is an ellagitannin and a gallate ester.
Corilagin is a natural product found in Euphorbia fischeriana, Euphorbia hyssopifolia, and other organisms with data available.
Corilagin is a gallotannin. It can be found in Alchornea glandulosa. [Wikipedia]
Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues[1][2][3].
Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues[1][2][3].

同义名列表

22 个代谢物同义名

(1S,19R,21S,22R,23R)-6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-2,17,20-trioxatetracyclo[17.3.1.0^{4,9}.0^{10,15}]tricosa-4,6,8,10,12,14-hexaen-21-yl 3,4,5-trihydroxybenzoate; [(1S,19R,21S,22R,23R)-6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-2,17,20-trioxatetracyclo[17.3.1.04,9.010,15]tricosa-4,6,8,10,12,14-hexaen-21-yl] 3,4,5-trihydroxybenzoate; 6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-21-(3,4,5-trihydroxyphenylcarbonyloxy)-2,17,20-trioxatetracyclo[17.3.1.04,9.010,15]tricosa-4(9),5,7,10(15),11,13-hexaene; 6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-21-(3,4,5-trihydroxyphenylcarbonyloxy)-2,17,20-trioxatetracyclo[17.3.1.04,9.010,15]tricosa-4,6,8,10,12,14-hexaene; .beta.-D-Glucopyranose, cyclic 3,6-[(1R)-(4,4,5,5,6,6-hexahydroxy[1,1-biphenyl]-2,2-dicarboxylate] 1-(3,4,5-trihydroxybenzoate); beta-D-Glucopyranose, cyclic 3,6-(4,4,5,5,6,6-hexahydroxy[1,1-biphenyl]-2,2-dicarboxylate) 1-(3,4,5-trihydroxybenzoate); 3-O,6-O-[carbonyl(4,4,5,5,6,6-hexahydroxybiphenyl-2,2-diyl)carbonyl]-1-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranose; 1-O-galloyl-3,6-hexahydroxydiphenic acid-beta-D-glucopyranose; 1-O-Galloyl-3,6-hexahydroxydiphenic acid-b-D-glucopyranose; 1-O-Galloyl-3,6-hexahydroxydiphenic acid-β-D-glucopyranose; (beta-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose); 1-O-Galloyl-3,6-hexahydroxydiphenate-beta-D-glucopyranose; (b-1-O-Galloyl-3,6-(R)-hexahydroxydiphenoyl-D-glucose); 1-O-Galloyl-3,6-hexahydroxydiphenate-β-D-glucopyranose; 1-O-Galloyl-3,6-hexahydroxydiphenate-b-D-glucopyranose; 1-O-galloyl-3,6-(R)-hexahydroxydiphenol-beta-D-glucose; (Β-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-D-glucose); Corilagin, analytical standard; Corilagin,(S); Corillagin; Corilagin; SCHEMBL13242674



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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144 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yunxiang Wang, Bin Li, Guanting Liu, Qipeng Han, Yunpeng Diao, Jing Liu. Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction. Life sciences. 2023 Oct; 334(?):122176. doi: 10.1016/j.lfs.2023.122176. [PMID: 37858718]
  • Yuhua Wang, Sha Huang, Wen Kong, Chaofeng Wu, Ting Zeng, Shuwen Xie, Qing Chen, Shanshan Kuang, Ruise Zheng, Fengsui Wang, Chuying Zhou, Yuyao Chen, Shaohui Huang, Zhiping Lv. Corilagin alleviates liver fibrosis in zebrafish and mice by repressing IDO1-mediated M2 macrophage repolarization. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Oct; 119(?):155016. doi: 10.1016/j.phymed.2023.155016. [PMID: 37598639]
  • Senquan Wu, Jia Liao, Guodong Hu, Liang Yan, Xingyu Su, Jiezhou Ye, Chanjuan Zhang, Tian Tian, Huadong Wang, Yiyang Wang. Corilagin alleviates LPS-induced sepsis through inhibiting pyroptosis via targeting TIR domain of MyD88 and binding CARD of ASC in macrophages. Biochemical pharmacology. 2023 Sep; ?(?):115806. doi: 10.1016/j.bcp.2023.115806. [PMID: 37714273]
  • M Tolmie, M J Bester, J C Serem, M Nell, Z Apostolides. The potential antidiabetic properties of green and purple tea [Camellia sinensis (L.) O Kuntze], purple tea ellagitannins, and urolithins. Journal of ethnopharmacology. 2023 Jun; 309(?):116377. doi: 10.1016/j.jep.2023.116377. [PMID: 36907477]
  • Bin Li, Wenlian Li, Meiling Zheng, Yunxiang Wang, Yunpeng Diao, Xiaojuan Mou, Jing Liu. Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway. Experimental biology and medicine (Maywood, N.J.). 2023 Jan; ?(?):15353702221147560. doi: 10.1177/15353702221147560. [PMID: 36680375]
  • XueJia Wang, David Fisher, Khrystyna Pronyuk, Yiping Dang, Lei Zhao. Agent in Urgent Need of Clinical Practice: Corilagin. Mini reviews in medicinal chemistry. 2023 Jan; ?(?):. doi: 10.2174/1389557523666230112110317. [PMID: 36635908]
  • Kenji Kubo, Hikaru Watanabe, Hiroyuki Kumeta, Tomoyasu Aizawa, Chigusa Seki, Hiroto Nakano, Kiyotaka Tokuraku, Koji Uwai. Chemical analysis of amyloid β aggregation inhibitors derived from Geranium thunbergii. Bioorganic & medicinal chemistry. 2022 08; 68(?):116840. doi: 10.1016/j.bmc.2022.116840. [PMID: 35661848]
  • Li Zhang, Bingxin Jia, Periyannan Velu, Hong Wu. Corilagin induces apoptosis and inhibits HMBG1/PI3K/AKT signaling pathways in a rat model of gastric carcinogenesis induced by methylnitronitrosoguanidine. Environmental toxicology. 2022 May; 37(5):1222-1230. doi: 10.1002/tox.23478. [PMID: 35103375]
  • Bo He, Deyun Chen, Xiaochao Zhang, Renhua Yang, Yuan Yang, Peng Chen, Zhiqiang Shen. Antiatherosclerotic effects of corilagin via suppression of the LOX-1/MyD88/NF-κB signaling pathway in vivo and in vitro. Journal of natural medicines. 2022 Mar; 76(2):389-401. doi: 10.1007/s11418-021-01594-y. [PMID: 35064897]
  • Mohamed Haddad, Roger Gaudreault, Gabriel Sasseville, Phuong Trang Nguyen, Hannah Wiebe, Theo Van De Ven, Steve Bourgault, Normand Mousseau, Charles Ramassamy. Molecular Interactions of Tannic Acid with Proteins Associated with SARS-CoV-2 Infectivity. International journal of molecular sciences. 2022 Feb; 23(5):. doi: 10.3390/ijms23052643. [PMID: 35269785]
  • Yue Shen, Li Teng, Yuhan Qu, Jie Liu, Xudong Zhu, Shan Chen, Longfei Yang, Yuehui Huang, Qin Song, Qiang Fu. Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways. Journal of ethnopharmacology. 2022 Feb; 284(?):114791. doi: 10.1016/j.jep.2021.114791. [PMID: 34737112]
  • Jing Huang, Ying Lei, Shengping Lei, Xinwen Gong. Cardioprotective effects of corilagin on doxorubicin induced cardiotoxicity via P13K/Akt and NF-κB signaling pathways in a rat model. Toxicology mechanisms and methods. 2022 Feb; 32(2):79-86. doi: 10.1080/15376516.2021.1965274. [PMID: 34369273]
  • Shu Jia, Dongye He, Xiao Liang, Panpan Cheng, Jilan Liu, Mingtai Chen, Cuiling Wang, Hao Zhang, Chunyang Meng. Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis. Molecular medicine reports. 2022 01; 25(1):. doi: 10.3892/mmr.2021.12550. [PMID: 34850958]
  • Haibo Yuan, Jinghong Zhang, Xiaosong Yin, Tongwei Liu, Xiao Yue, Chuangui Li, Yuanyuan Wang, Ding Li, Qiang Wang. The protective role of corilagin on renal calcium oxalate crystal-induced oxidative stress, inflammatory response, and apoptosis via PPAR-γ and PI3K/Akt pathway in rats. Biotechnology and applied biochemistry. 2021 Dec; 68(6):1323-1331. doi: 10.1002/bab.2054. [PMID: 33080078]
  • Eshetu M Bobasa, Anh Dao Thi Phan, Michael E Netzel, Daniel Cozzolino, Yasmina Sultanbawa. Hydrolysable tannins in Terminalia ferdinandiana Exell fruit powder and comparison of their functional properties from different solvent extracts. Food chemistry. 2021 Oct; 358(?):129833. doi: 10.1016/j.foodchem.2021.129833. [PMID: 33933967]
  • Yiting Tao, Li Zhang, Renhua Yang, Yongzhao Yang, Haonan Jin, Xiaochao Zhang, Qin Hu, Bo He, Zhiqiang Shen, Peng Chen. Corilagin ameliorates atherosclerosis by regulating MMP-1, -2, and -9 expression in vitro and in vivo. European journal of pharmacology. 2021 Sep; 906(?):174200. doi: 10.1016/j.ejphar.2021.174200. [PMID: 34062170]
  • Vincent Binette, Sébastien Côté, Mohamed Haddad, Phuong Trang Nguyen, Sébastien Bélanger, Steve Bourgault, Charles Ramassamy, Roger Gaudreault, Normand Mousseau. Corilagin and 1,3,6-Tri-O-galloy-β-D-glucose: potential inhibitors of SARS-CoV-2 variants. Physical chemistry chemical physics : PCCP. 2021 Jul; 23(27):14873-14888. doi: 10.1039/d1cp01790j. [PMID: 34223589]
  • Li Jun Yang, Rui Hong Chen, Sami Hamdoun, Paolo Coghi, Jerome P L Ng, David Wei Zhang, Xiaoling Guo, Chenglai Xia, Betty Yuen Kwan Law, Vincent Kam Wai Wong. Corilagin prevents SARS-CoV-2 infection by targeting RBD-ACE2 binding. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 Jul; 87(?):153591. doi: 10.1016/j.phymed.2021.153591. [PMID: 34029937]
  • Huijun Wang, Mark I Fowler, David J Messenger, Jose Juan Ordaz-Ortiz, Xuelan Gu, Songshan Shi, Leon A Terry, Mark J Berry, Guoping Lian, Shunchun Wang. Inhibition of the intestinal postprandial glucose transport by gallic acid and gallic acid derivatives. Food & function. 2021 Jun; 12(12):5399-5406. doi: 10.1039/d1fo01118a. [PMID: 33988204]
  • Maura Z Dos Santos, Janaína de Ávila, Ademir Morel, Thais S Canto-Dorow, Marco A Mostardeiro, Ionara I Dalcol. Evaluation of prolyl oligopeptidase and acetylcholinesterase inhibition by Phyllanthus tenellus Roxb. from Brazil. Natural product research. 2021 Jun; 35(11):1840-1846. doi: 10.1080/14786419.2019.1637869. [PMID: 31282201]
  • Chaoqun Wu, Huiqi Huang, Ho-Young Choi, Yuanren Ma, Tongxi Zhou, Yu Peng, Kejian Pang, Guangwen Shu, Xinzhou Yang. Anti-esophageal Cancer Effect of Corilagin Extracted from Phmllanthi Fructus via the Mitochondrial and Endoplasmic Reticulum Stress Pathways. Journal of ethnopharmacology. 2021 Apr; 269(?):113700. doi: 10.1016/j.jep.2020.113700. [PMID: 33346026]
  • Nur Zahirah Abd Rani, Kok Wai Lam, Juriyati Jalil, Hazni Falina Mohamad, Mohd Shukri Mat Ali, Khairana Husain. Mechanistic Studies of the Antiallergic Activity of Phyllanthus amarus Schum. & Thonn. and Its Compounds. Molecules (Basel, Switzerland). 2021 Jan; 26(3):. doi: 10.3390/molecules26030695. [PMID: 33525733]
  • Atul R Chopade, Rahul P Pol, Pramod A Patil, Vyankatesh R Dharanguttikar, Nilofar S Naikwade, Remeth J Dias, Suraj N Mali. An Insight Into the Anxiolytic Effects of Lignans (Phyllanthin and Hypophyllanthin) and Tannin (Corilagin) Rich Extracts of Phyllanthus amarus : An In-Silico and In-vivo approaches. Combinatorial chemistry & high throughput screening. 2021; 24(3):415-422. doi: 10.2174/1386207323666200605150915. [PMID: 32503404]
  • Fenglian Yan, Dalei Cheng, Haiyan Wang, Min Gao, Junfeng Zhang, Hongyan Cheng, Changying Wang, Hui Zhang, Huabao Xiong. Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization. Frontiers in immunology. 2021; 12(?):807509. doi: 10.3389/fimmu.2021.807509. [PMID: 35095894]
  • Asiri Perera, So Ha Ton, Mohanambal Moorthy, Uma Devi Palanisamy. The insulin-sensitising properties of the ellagitannin geraniin and its metabolites from Nephelium lappaceum rind in 3T3-L1 cells. International journal of food sciences and nutrition. 2020 Dec; 71(8):940-953. doi: 10.1080/09637486.2020.1754348. [PMID: 32319838]
  • Xican Li, Jie Liu, Ban Chen, Yingci Chen, Wanjian Dai, Yuling Li, Meiling Zhu. Covalent Bridging of Corilagin Improves Antiferroptosis Activity: Comparison with 1,3,6-Tri-O-galloyl-β-d-glucopyranose. ACS medicinal chemistry letters. 2020 Nov; 11(11):2232-2237. doi: 10.1021/acsmedchemlett.0c00359. [PMID: 33214834]
  • Ashutosh Gupta, Ramesh Kumar, Piyali Bhattacharyya, Anupam Bishayee, Abhay K Pandey. Terminalia bellirica (Gaertn.) roxb. (Bahera) in health and disease: A systematic and comprehensive review. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Oct; 77(?):153278. doi: 10.1016/j.phymed.2020.153278. [PMID: 32781393]
  • Xiaodong Hou, Zitao Cheng, Jiao Wang. Preparative purification of corilagin from Phyllanthus by combining ionic liquid extraction, prep-HPLC, and precipitation. Analytical methods : advancing methods and applications. 2020 07; 12(26):3382-3389. doi: 10.1039/d0ay00860e. [PMID: 32930226]
  • Guliqire Adili, Guangying Sun, Munire Abuduaini, Yongxin Zhao, Rahima Abdulla, Haji Akber Aisa. Simultaneous determination of loading capacity and selectivity in preparative off-line two-dimensional separation: An application for purification of corilagin from Pomegranate flower extracts. Journal of chromatography. A. 2020 Jul; 1622(?):461129. doi: 10.1016/j.chroma.2020.461129. [PMID: 32376025]
  • Wei Chen, XianMin Shen, Li Ma, Rong Chen, Qin Yuan, YunFeng Zheng, CunYu Li, GuoPing Peng. Phenolic Compounds from Polygonum chinense Induce Growth Inhibition and Apoptosis of Cervical Cancer SiHa Cells. BioMed research international. 2020; 2020(?):8868508. doi: 10.1155/2020/8868508. [PMID: 33381593]
  • Yiqing Li, Yujie Wang, Yunfei Chen, Yao Wang, Shaojun Zhang, Pan Liu, Zhilin Chen, Peng Song, Lei Luo, Yingying Luo, Yiping Dang, Lei Zhao. Corilagin Ameliorates Atherosclerosis in Peripheral Artery Disease via the Toll-Like Receptor-4 Signaling Pathway in vitro and in vivo. Frontiers in immunology. 2020; 11(?):1611. doi: 10.3389/fimmu.2020.01611. [PMID: 32849545]
  • Kun Li, Xianwei Han, Ruzhuo Li, Zhongren Xu, Taowen Pan, Jing Liu, Bin Li, Shouyu Wang, Yunpeng Diao, Xinguang Liu. Composition, Antivirulence Activity, and Active Property Distribution of the Fruit of Terminalia chebula Retz. Journal of food science. 2019 Jul; 84(7):1721-1729. doi: 10.1111/1750-3841.14655. [PMID: 31206192]
  • Zainaipuguli Yisimayili, Xiaozhen Guo, Huan Liu, Zhou Xu, Rahima Abdulla, Haji Akber Aisa, Chenggang Huang. Metabolic profiling analysis of corilagin in vivo and in vitro using high-performance liquid chromatography quadrupole time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2019 Feb; 165(?):251-260. doi: 10.1016/j.jpba.2018.12.013. [PMID: 30562708]
  • Xuelian Bai, Rui Pan, Mingzhu Li, Xiuting Li, Huawei Zhang. HPLC Profile of Longan (cv. Shixia) Pericarp-Sourced Phenolics and Their Antioxidant and Cytotoxic Effects. Molecules (Basel, Switzerland). 2019 Feb; 24(3):. doi: 10.3390/molecules24030619. [PMID: 30754614]
  • H S Nandini, Prakash Ramachandra Naik. Action of corilagin on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats. Chemico-biological interactions. 2019 Feb; 299(?):186-193. doi: 10.1016/j.cbi.2018.12.012. [PMID: 30582900]
  • Omolara F Yakubu, Abiodun H Adebayo, Titilope M Dokunmu, Ying-Jun Zhang, Emeka E J Iweala. Cytotoxic Effects of Compounds Isolated from Ricinodendron heudelotii. Molecules (Basel, Switzerland). 2019 Jan; 24(1):. doi: 10.3390/molecules24010145. [PMID: 30609707]
  • Xuan Zhou, Jun Xiong, Shi Lu, Lei Luo, Zhi-Lin Chen, Fan Yang, Feng Jin, Yao Wang, Qian Ma, Ying-Ying Luo, Yu-Jie Wang, Jia-Bin Zhou, Pan Liu, Lei Zhao. Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway. The American journal of Chinese medicine. 2019; 47(7):1541-1569. doi: 10.1142/s0192415x19500794. [PMID: 31752524]
  • Michael Afolayan, Radhakrishnan Srivedavyasasri, Olayinka T Asekun, Oluwole B Familoni, Samir A Ross. Chemical and biological studies on Bridelia ferruginea grown in Nigeria. Natural product research. 2019 Jan; 33(2):287-291. doi: 10.1080/14786419.2018.1440225. [PMID: 29457749]
  • Fanghua Qiu, Lifang Liu, Yu Lin, Zetian Yang, Feng Qiu. Corilagin Inhibits Esophageal Squamous Cell Carcinoma by Inducing DNA Damage and Down-Regulation of RNF8. Anti-cancer agents in medicinal chemistry. 2019; 19(8):1021-1028. doi: 10.2174/1871520619666190307120811. [PMID: 30848215]
  • Yujing Li, Zhaojie Li, Hu Hou, Yongliang Zhuang, Liping Sun. Metal Chelating, Inhibitory DNA Damage, and Anti-Inflammatory Activities of Phenolics from Rambutan (Nephelium lappaceum) Peel and the Quantifications of Geraniin and Corilagin. Molecules (Basel, Switzerland). 2018 Sep; 23(9):. doi: 10.3390/molecules23092263. [PMID: 30189625]
  • Hao-Zhou Huang, Sheng-Yu Zhao, Xiu-Mei Ke, Jun-Zhi Lin, Shu-Sen Huang, Run-Chun Xu, Hong-Yan Ma, Yi Zhang, Li Han, Ding-Kun Zhang. Study on the stability control strategy of Triphala solution based on the balance of physical stability and chemical stabilities. Journal of pharmaceutical and biomedical analysis. 2018 Sep; 158(?):247-256. doi: 10.1016/j.jpba.2018.06.008. [PMID: 29890481]
  • Ni Li, Zhican Lin, Wei Chen, Yi Zheng, Yanlin Ming, Zhizhong Zheng, Wen Huang, Lianghua Chen, Jianbo Xiao, Hetong Lin. Corilagin from longan seed: Identification, quantification, and synergistic cytotoxicity on SKOv3ip and hey cells with ginsenoside Rh2 and 5-fluorouracil. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018 Sep; 119(?):133-140. doi: 10.1016/j.fct.2018.05.018. [PMID: 29751073]
  • Yuan Deng, Xudan Li, Xuan Li, Zhizhong Zheng, Wen Huang, Lianghua Chen, Qingxuan Tong, Yanlin Ming. Corilagin induces the apoptosis of hepatocellular carcinoma cells through the mitochondrial apoptotic and death receptor pathways. Oncology reports. 2018 Jun; 39(6):2545-2552. doi: 10.3892/or.2018.6396. [PMID: 29693193]
  • Xuedan Huang, Mingzhu Xu, Tatsuya Shirahata, Wei Li, Kazuo Koike, Akiko Kojima-Yuasa, Isao Yuasa, Yoshinori Kobayashi. Anti-steatosis compounds from leaves of Mallotus furetianus. Natural product research. 2018 Jun; 32(12):1459-1462. doi: 10.1080/14786419.2017.1350664. [PMID: 28693358]
  • Xue Yu, Tao Zhou, Heng Yu, Li-Ying Chang, Ling-Li Wei. Corilagin Reduces the Frequency of Seizures and Improves Cognitive Function in a Rat Model of Chronic Epilepsy. Medical science monitor : international medical journal of experimental and clinical research. 2018 May; 24(?):2832-2840. doi: 10.12659/msm.906509. [PMID: 29730669]
  • Fan Yang, Yao Wang, Gang Li, Juan Xue, Zhi-Lin Chen, Feng Jin, Lei Luo, Xuan Zhou, Qian Ma, Xin Cai, Hua-Rong Li, Lei Zhao. Effects of corilagin on alleviating cholestasis via farnesoid X receptor-associated pathways in vitro and in vivo. British journal of pharmacology. 2018 03; 175(5):810-829. doi: 10.1111/bph.14126. [PMID: 29235094]
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