Daidzin (BioDeep_00000002593)

natural product human metabolite PANOMIX_OTCML-2023

代谢物信息卡片

3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

化学式: C21H20O9 (416.110727)
中文名称: 大豆苷, 黄豆甙, 大豆甙, 豆苷, 豆苷, 黄豆苷
谱图信息: 最多检出来源 Macaca mulatta(otcml) 0.05%

分子结构信息

SMILES: c1(ccc2c(c1)occ(c2=O)c1ccc(cc1)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
InChI: InChI=1/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1

描述信息

Daidzein 7-O-beta-D-glucoside is a glycosyloxyisoflavone that is daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic). It has a role as a plant metabolite. It is a hydroxyisoflavone, a monosaccharide derivative and a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a daidzein.
Daidzin is a natural product found in Thermopsis lanceolata, Thermopsis macrophylla, and other organisms with data available.
See also: Astragalus propinquus root (part of).
Daidzin is found in miso. Daidzin is isolated from soya bean (Glycine max) and soya bean meal, kudzu root (Pueraria lobata), alfalfa (Medicago sativa) and other Leguminosae.Daidzin is a cancer preventive and an alcohol dependency treatment (antidipsotropic) in animal models. Daidzin is a natural organic compound in the class of phytochemicals known as isoflavones. Daidzin can be found in Japanese plant Kudzu (Pueraria lobata, Fabaceae) and from soybean leaves
A glycosyloxyisoflavone that is daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic).
Isolated from soya bean (Glycine max) and soya bean meal, kudzu root (Pueraria lobata), alfalfa (Medicago sativa) and other Leguminosae
D002491 - Central Nervous System Agents > D000427 - Alcohol Deterrents
D004791 - Enzyme Inhibitors
Acquisition and generation of the data is financially supported in part by CREST/JST.
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities.
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption[1].
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities.

同义名列表

50 个代谢物同义名

3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; 3-(4-hydroxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one; 3-(4-hydroxyphenyl)-7-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one; 3-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one; 3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one; 7-(beta-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl beta-D-glucopyranoside; 7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-chromen-4-one; 3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside; Daidzin, United States Pharmacopeia (USP) Reference Standard; Daidzin, primary pharmaceutical reference standard; 4,7-DIHYDROXYISOFLAVONE; 7-O-B-D-GLUCOPYRANOSIDE; 4,7-Dihydroxyisoflavone 7-O-b-D-glucopyranoside; DAIDZIN (CONSTITUENT OF SOY ISOFLAVONES) [DSC]; 4-18-00-01808 (Beilstein Handbook Reference); DAIDZIN (CONSTITUENT OF ASTRAGALUS) [DSC]; DAIDZIN (CONSTITUENT OF SOY ISOFLAVONES); 7,4-Dihydroxyisoflavone 7-glucoside; DAIDZIN (CONSTITUENT OF ASTRAGALUS); Daidzein 7-O-beta-D-glucopyranoside; Daidzein 7-O-|A-D-glucopyranoside; 7-O-glucosyl-4-hydroxyisoflavone; DAIDZEIN 7-O-.BETA.-D-GLUCOSIDE; daidzein 7-O-beta-D-glucoside; Daidzin, analytical standard; KYQZWONCHDNPDP-QNDFHXLGSA-N; 7-O-beta-D-glucopyranoside; Daidzein 7-O-β-D-glucoside; Daidzein 7-O-b-D-glucoside; Daidzin, >=95.0\\% (HPLC); daidzein-7-o-glucoside; Daidzein 7-O-glucoside; DAIDZEIN DAIDZIN [MI]; Daidzein 7-glucoside; Daidzein-7-glucoside; DAIDZEIN DAIDZIN; DAIDZIN [USP-RS]; DAIDZIN (USP-RS); UNII-4R2X91A5M5; MEGxp0_000530; ACon1_002092; Daidzoside; 4R2X91A5M5; Daidzin; Dadzin; 2vle; DZN; Daidzein-7-O-β-D-glucopyranoside; Daidzein O-hexoside; NPI-031D

数据库引用编号

46 个数据库交叉引用编号

ChEBI: CHEBI:42202
KEGG: C10216
PubChem: 107971
HMDB: HMDB0033991
Metlin: METLIN64304
DrugBank: DB02115
ChEMBL: CHEMBL486422
Wikipedia: Daidzin
LipidMAPS: LMPK12050013
MeSH: daidzin
ChemIDplus: 0000552669
MetaCyc: CPD-3424
KNApSAcK: C00002518
foodb: FDB012225
chemspider: 97088
CAS: 552-66-9
MoNA: PS043806
MoNA: PR020022
MoNA: PS043811
MoNA: PS043803
MoNA: PR040207
MoNA: PS043804
MoNA: PS043805
MoNA: PR040204
MoNA: PS043802
MoNA: PR100680
MoNA: PR040202
MoNA: PS043810
MoNA: PR040208
MoNA: PS043808
MoNA: PR100257
MoNA: PR040206
MoNA: PR040203
MoNA: PR040209
MoNA: PS043807
MoNA: PS043801
MoNA: PR040205
MoNA: PS043809
medchemexpress: HY-N0018
PMhub: MS000004056
MetaboLights: MTBLC42202
PubChem: 12402
PDB-CCD: DZN
3DMET: B03643
NIKKAJI: J22.589D
RefMet: Daidzin

分类词条

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

daidzein conjugates interconversion: H₂O + daidzin ⟶ D-glucopyranose + daidzein
daidzin and daidzein degradation: (3R,4S)-tetrahydrodaidzein + A(H2) ⟶ (S)-equol + A + H₂O

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

81 个相关的物种来源信息

33090 大豆: -
78253 Begonia nantoensis: 10.1248/CPB.52.345
147456 Genista sessilifolia: 10.1007/S10600-009-9248-7
714518 Ziziphus jujuba var. spinosa: 10.1111/J.1744-7909.2005.00060.X
3847 Glycine max:
242867 Cicer flexuosum: 10.1007/BF00629810
705300 Ormosia henryi: 10.1016/J.FITOTE.2011.10.007
22663 Punica granatum: 10.1016/S0021-9673(00)90278-4
3893 Pueraria montana var. lobata:
861244 Pueraria candollei var. mirifica:
57577 Trifolium pratense:
49838 Retama sphaerocarpa:
1969221 Baptisia lanceolata: 10.1016/S0031-9422(00)85740-4
1969223 Baptisia megacarpa: 10.1016/S0031-9422(00)85740-4
1871516 Baptisia perfoliata: 10.1016/S0031-9422(00)85740-4
1969224 Baptisia simplicifolia: 10.1016/S0031-9422(00)85740-4
313912 Baptisia bracteata: 10.1016/S0031-9422(00)85740-4
1969220 Baptisia calycosa: 10.1016/S0031-9422(00)85740-4
313913 Baptisia cinerea: 10.1016/S0031-9422(00)85740-4
114320 Thermopsis lanceolata: 10.1248/CPB.28.3686
157791 Vigna radiata: 10.1007/BF00633405
1969222 Baptisia lecontei: 10.1016/S0031-9422(00)84834-7
520843 Flemingia macrophylla: 10.1016/S0031-9422(97)00243-4
1770154 Sorbus cuspidata: 10.1016/J.PHYTOCHEM.2010.08.015
3892 Pueraria: 10.1248/YAKUSHI1947.79.6_757
46114 Froelichia floridana: 10.1016/J.PHYTOCHEM.2009.01.017
1883 Streptomyces:
1888360 Bituminaria acaulis: 10.1007/BF00567888
3827 Cicer arietinum: 10.1515/ZNC-1987-11-1206
114325 Thermopsis villosa: 10.1016/S0031-9422(00)88458-7
2805045 Thermopsis mollis: 10.1016/S0031-9422(00)88458-7
114322 Thermopsis macrophylla: 10.1016/S0031-9422(00)88458-7
61122 Thermopsis rhombifolia: 10.1016/S0031-9422(00)88458-7
457826 Pueraria tuberosa: 10.1016/S0021-9673(01)95520-7
175395 Adenocarpus decorticans: 10.1016/J.BSE.2011.12.023
692153 Adenocarpus artemisiifolius: 10.1016/J.BSE.2011.12.023
3846 Glycine: 10.1021/JF803870K
37501 Maackia amurensis: 10.1021/JF801227Q
3914 Vigna angularis:
3844 Erythrina latissima: 10.1093/JAOAC/84.2.451
78253 Begonia nantoensis: 10.1248/CPB.52.345
147456 Genista sessilifolia: 10.1007/S10600-009-9248-7
714518 Ziziphus jujuba var. spinosa: 10.1111/J.1744-7909.2005.00060.X
3847 Glycine max:
242867 Cicer flexuosum: 10.1007/BF00629810
705300 Ormosia henryi: 10.1016/J.FITOTE.2011.10.007
22663 Punica granatum: 10.1016/S0021-9673(00)90278-4
3893 Pueraria montana var. lobata:
861244 Pueraria candollei var. mirifica:
57577 Trifolium pratense:
49838 Retama sphaerocarpa:
1969221 Baptisia lanceolata: 10.1016/S0031-9422(00)85740-4
1969223 Baptisia megacarpa: 10.1016/S0031-9422(00)85740-4
1871516 Baptisia perfoliata: 10.1016/S0031-9422(00)85740-4
1969224 Baptisia simplicifolia: 10.1016/S0031-9422(00)85740-4
313912 Baptisia bracteata: 10.1016/S0031-9422(00)85740-4
1969220 Baptisia calycosa: 10.1016/S0031-9422(00)85740-4
313913 Baptisia cinerea: 10.1016/S0031-9422(00)85740-4
114320 Thermopsis lanceolata: 10.1248/CPB.28.3686
157791 Vigna radiata: 10.1007/BF00633405
1969222 Baptisia lecontei: 10.1016/S0031-9422(00)84834-7
520843 Flemingia macrophylla: 10.1016/S0031-9422(97)00243-4
1770154 Sorbus cuspidata: 10.1016/J.PHYTOCHEM.2010.08.015
3892 Pueraria: 10.1248/YAKUSHI1947.79.6_757
46114 Froelichia floridana: 10.1016/J.PHYTOCHEM.2009.01.017
1883 Streptomyces:
1888360 Bituminaria acaulis: 10.1007/BF00567888
3827 Cicer arietinum: 10.1515/ZNC-1987-11-1206
114325 Thermopsis villosa: 10.1016/S0031-9422(00)88458-7
2805045 Thermopsis mollis: 10.1016/S0031-9422(00)88458-7
114322 Thermopsis macrophylla: 10.1016/S0031-9422(00)88458-7
61122 Thermopsis rhombifolia: 10.1016/S0031-9422(00)88458-7
457826 Pueraria tuberosa: 10.1016/S0021-9673(01)95520-7
175395 Adenocarpus decorticans: 10.1016/J.BSE.2011.12.023
692153 Adenocarpus artemisiifolius: 10.1016/J.BSE.2011.12.023
3846 Glycine: 10.1021/JF803870K
37501 Maackia amurensis: 10.1021/JF801227Q
3914 Vigna angularis:
3844 Erythrina latissima: 10.1093/JAOAC/84.2.451
9606 Homo sapiens: -
33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Shuai Yuan, Ibrahim Abdel Aziz Ibrahim, Ruimin Ren. Anti-urolithiatic Activity of Daidzin in Ethylene Glycol-Induced Urolithiasis in Rats. Applied biochemistry and biotechnology. 2023 Feb; 195(2):905-918. doi: 10.1007/s12010-022-04124-y. [PMID: 36227501]
Quanli Liu, Yi Liu, Gang Li, Otto Savolainen, Yun Chen, Jens Nielsen. De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories. Nature communications. 2021 10; 12(1):6085. doi: 10.1038/s41467-021-26361-1. [PMID: 34667183]
Dan Gao, Jin Hyeok Kim, Cheong Taek Kim, Won Seok Jeong, Hyung Min Kim, Jaehoon Sim, Jong Seong Kang. Evaluation of Anti-Melanogenesis Activity of Enriched Pueraria lobata Stem Extracts and Characterization of Its Phytochemical Components Using HPLC-PDA-ESI-MS/MS. International journal of molecular sciences. 2021 Jul; 22(15):. doi: 10.3390/ijms22158105. [PMID: 34360871]
Miwako Toyofuku, Fuki Okutani, Masaru Nakayasu, Shoichiro Hamamoto, Hisabumi Takase, Kazufumi Yazaki, Akifumi Sugiyama. Enhancement of developmentally regulated daidzein secretion from soybean roots in field conditions as compared with hydroponic culture. Bioscience, biotechnology, and biochemistry. 2021 Apr; 85(5):1165-1169. doi: 10.1093/bbb/zbab017. [PMID: 33784734]
Su-Jin Ahn, Hyung Joo Kim, Ayoung Lee, Seung-Sik Min, Sangwhan In, Eunmi Kim. Determination of 12 herbal compounds for estimating the presence of Angelica Gigas Root, Cornus Fruit, Licorice Root, Pueraria Root, and Schisandra Fruit in foods by LC-MS/MS. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2020 Sep; 37(9):1437-1448. doi: 10.1080/19440049.2020.1778187. [PMID: 32530783]
Zartashia Kazmi, Sara Zeeshan, Adnan Khan, Sumra Malik, Adeeb Shehzad, Eun Kyoung Seo, Salman Khan. Anti-epileptic activity of daidzin in PTZ-induced mice model by targeting oxidative stress and BDNF/VEGF signaling. Neurotoxicology. 2020 07; 79(?):150-163. doi: 10.1016/j.neuro.2020.05.005. [PMID: 32450180]
You Jin Lim, Ho Young Jeong, Chan Saem Gil, Soon-Jae Kwon, Jong Kuk Na, Chanhui Lee, Seok Hyun Eom. Isoflavone accumulation and the metabolic gene expression in response to persistent UV-B irradiation in soybean sprouts. Food chemistry. 2020 Jan; 303(?):125376. doi: 10.1016/j.foodchem.2019.125376. [PMID: 31442900]
Yingjie Sun, Hongmin Zhang, Ming Cheng, Shijie Cao, Miao Qiao, Boli Zhang, Liqin Ding, Feng Qiu. New hepatoprotective isoflavone glucosides from Pueraria lobata (Willd.) Ohwi. Natural product research. 2019 Dec; 33(24):3485-3492. doi: 10.1080/14786419.2018.1484461. [PMID: 29968479]
Kung-Chieh Wu, Wei-Yu Lin, Yi-Ting Sung, Wei-Yi Wu, Yu-Hsiuan Cheng, Tung-Sheng Chen, Bing-Juin Chiang, Chiang-Ting Chien. Glycine tomentella hayata extract and its ingredient daidzin ameliorate cyclophosphamide-induced hemorrhagic cystitis and oxidative stress through the action of antioxidation, anti-fibrosis, and anti-inflammation. The Chinese journal of physiology. 2019 Sep; 62(5):188-195. doi: 10.4103/cjp.cjp_60_19. [PMID: 31670282]
Juping Zhang, Qianxiang Guo, Meijin Wei, Junqi Bai, Juan Huang, Yuhong Liu, Ziren Su, Xiaohui Qiu. Metabolite Identification and Pharmacokinetic Profiling of Isoflavones from Black Soybean in Rats Using Ultrahigh-Performance Liquid Chromatography with Linear-Ion-Trap-Orbitrap and Triple-Quadrupole Tandem Mass Spectrometry. Journal of agricultural and food chemistry. 2018 Dec; 66(49):12941-12952. doi: 10.1021/acs.jafc.8b04852. [PMID: 30444115]
Kung-Chieh Wu, Bing-Juin Chiang, Wen-Hsin Tsai, Shiu-Dong Chung, Chiang-Ting Chien. I-Tiao-Gung extract through its active component daidzin improves cyclophosphamide-induced bladder dysfunction in rat model. Neurourology and urodynamics. 2018 11; 37(8):2560-2570. doi: 10.1002/nau.23815. [PMID: 30252154]
Paulo Luiz DA Silva, Gláucia Cordeiro, Carolina R DA Silva, Rafael A Barros, Camila R DA Silva, José C Zanuncio, Wellington G Campos, Maria G A Oliveira. Does mechanical damage on soybean induces the production of flavonoids?. Anais da Academia Brasileira de Ciencias. 2018 Oct; 90(4):3415-3422. doi: 10.1590/0001-3765201820170850. [PMID: 30365711]
Feng Qiu, Linyi Shi, Siqi Wang, Sha Wu, Manyuan Wang. Simultaneous high-performance liquid chromatography with diode array detection and time-of-flight mass spectrometric confirmation of the ten bioactive compounds in Semen Sojae Preparatum. Journal of separation science. 2018 Sep; 41(17):3360-3371. doi: 10.1002/jssc.201800504. [PMID: 30016573]
Charles C Lee, Stéphanie Dudonné, Jong Hun Kim, Ji Seung Kim, Pascal Dubé, Jong-Eun Kim, Yves Desjardins, Jung Han Yoon Park, Ki Won Lee, Chang Yong Lee. A major daidzin metabolite 7,8,4'-trihydroxyisoflavone found in the plasma of soybean extract-fed rats attenuates monocyte-endothelial cell adhesion. Food chemistry. 2018 Feb; 240(?):607-614. doi: 10.1016/j.foodchem.2017.08.002. [PMID: 28946319]
Mei-Yan Yang, Ya-Bin Wang, Bo Han, Bo Yang, Yu-Wei Qiang, Yan Zhang, Zhao Wang, Xu Huang, Jie Liu, Yun-Dai Chen, Jun Ren, Feng Cao, Yong Xu. Activation of aldehyde dehydrogenase 2 slows down the progression of atherosclerosis via attenuation of ER stress and apoptosis in smooth muscle cells. Acta pharmacologica Sinica. 2018 Jan; 39(1):48-58. doi: 10.1038/aps.2017.81. [PMID: 28858301]
Yunjeong Kim, Ji-Young Jeon, Eun-Young Kim, Cheol-Hee Lim, Hwan Bong Jang, Min-Gul Kim. Pharmacokinetics and Safety of DW1029M, a Botanical Drug for the Treatment of Diabetic Nephropathy, Following Single Doses in Healthy Subjects. Clinical pharmacology in drug development. 2017 Sep; 6(5):499-507. doi: 10.1002/cpdd.343. [PMID: 28301092]
Xiao-Ling Wang, Fu-Rong Jiao, Meng Yu, Li-Bin Lin, Jian Xiao, Qiang Zhang, Le Wang, Dong-Zhu Duan, Gang Xie. Constituents with potent α-glucosidase inhibitory activity from Pueraria lobata (Willd.) ohwi. Bioorganic & medicinal chemistry letters. 2017 05; 27(9):1993-1998. doi: 10.1016/j.bmcl.2017.03.013. [PMID: 28343876]
Alírica I Suárez, Zaw Min Thu, Jorge Ramírez, Diana León, Luis Cartuche, Chabaco Armijos, Geovanni Vidari. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Natural product communications. 2017 Apr; 12(4):533-535. doi: . [PMID: 30520590]
Hee Rae Kang, Dahae Lee, René Benndorf, Won Hee Jung, Christine Beemelmanns, Ki Sung Kang, Ki Hyun Kim. Termisoflavones A-C, Isoflavonoid Glycosides from Termite-Associated Streptomyces sp. RB1. Journal of natural products. 2016 Dec; 79(12):3072-3078. doi: 10.1021/acs.jnatprod.6b00738. [PMID: 28006913]
José P da Graça, Tatiana E Ueda, Tatiani Janegitz, Simone S Vieira, Mariana C Salvador, Maria C N de Oliveira, Sonia M Zingaretti, Stephen J Powers, John A Pickett, Michael A Birkett, Clara B Hoffmann-Campo. The natural plant stress elicitor cis-jasmone causes cultivar-dependent reduction in growth of the stink bug, Euschistus heros and associated changes in flavonoid concentrations in soybean, Glycine max. Phytochemistry. 2016 Nov; 131(?):84-91. doi: 10.1016/j.phytochem.2016.08.013. [PMID: 27659594]
Heung Joo Yuk, Yeong Hun Song, Marcus J Curtis-Long, Dae Wook Kim, Su Gyeong Woo, Yong Bok Lee, Zia Uddin, Cha Young Kim, Ki Hun Park. Ethylene Induced a High Accumulation of Dietary Isoflavones and Expression of Isoflavonoid Biosynthetic Genes in Soybean (Glycine max) Leaves. Journal of agricultural and food chemistry. 2016 Oct; 64(39):7315-7324. doi: 10.1021/acs.jafc.6b02543. [PMID: 27626287]
Mohd Zaheer, Vudem Dashavantha Reddy, Charu Chandra Giri. Enhanced daidzin production from jasmonic and acetyl salicylic acid elicited hairy root cultures of Psoralea corylifolia L. (Fabaceae). Natural product research. 2016 Jul; 30(13):1542-7. doi: 10.1080/14786419.2015.1054823. [PMID: 26156378]
Bili Su, Yongjun Kan, Jianwei Xie, Juan Hu, Wensheng Pang. Relevance of the Pharmacokinetic and Pharmacodynamic Profiles of Puerariae lobatae Radix to Aggregation of Multi-Component Molecules in Aqueous Decoctions. Molecules (Basel, Switzerland). 2016 Jun; 21(7):. doi: 10.3390/molecules21070845. [PMID: 27367654]
Naim Stiti, Balakumaran Chandrasekar, Laura Strubl, Shabaz Mohammed, Dorothea Bartels, Renier A L van der Hoorn. Nicotinamide Cofactors Suppress Active-Site Labeling of Aldehyde Dehydrogenases. ACS chemical biology. 2016 06; 11(6):1578-86. doi: 10.1021/acschembio.5b00784. [PMID: 26990764]
Kailee A Johnson, Sravan Vemuri, Sameerh Alsahafi, Rudy Castillo, Venugopalan Cheriyath. Glycone-rich Soy Isoflavone Extracts Promote Estrogen Receptor Positive Breast Cancer Cell Growth. Nutrition and cancer. 2016 May; 68(4):622-33. doi: 10.1080/01635581.2016.1154578. [PMID: 27043076]
Yan Zhang, Sam K C Chang. Isoflavone Profiles and Kinetic Changes during Ultra-High Temperature Processing of Soymilk. Journal of food science. 2016 Mar; 81(3):C593-9. doi: 10.1111/1750-3841.13236. [PMID: 26814612]
S Persiani, F Sala, C Manzotti, M Colovic, M Zangarini, Y Donazzolo, B Barbetta, C Vitalini, G Giacovelli, C Benvenuti, L C Rovati. Evaluation of Levothyroxine Bioavailability after Oral Administration of a Fixed Combination of Soy Isoflavones in Post-menopausal Female Volunteers. Drug research. 2016 Mar; 66(3):136-40. doi: 10.1055/s-0035-1555784. [PMID: 26125285]
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