Serotonin (BioDeep_00000229640)

Main id: BioDeep_00000398749

 

human metabolite PANOMIX_OTCML-2023 BioNovoGene_Lab2019 natural product


代谢物信息卡片


5-Hydroxytryptamine

化学式: C10H12N2O (176.095)
中文名称: 5-羟基色胺, 5-羟色胺(盐酸盐), 3-(2-氨乙酸)吲哚盐酸盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(C=C1O)C(=CN2)CCN
InChI: InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2

描述信息

D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists

同义名列表

3 个代谢物同义名

5-Hydroxytryptamine; Serotonin; Serotonin



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

161 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 CALCA, ENO2, GAL, NTRK2, POMC, PPY, PRL, TH
Endosome membrane 1 NTRK2
Nucleus 2 PRL, TH
cytosol 7 AVP, ENO2, LEP, NGF, NTRK2, PRKCQ, TH
dendrite 6 AVP, MAOB, NGF, NTRK2, SLC18A2, TH
centrosome 1 SLC18A2
nucleoplasm 1 PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 4 ENO2, GAL, NTRK2, OPRD1
Cytoplasmic side 1 MAOB
Cell projection, axon 3 NTRK2, SLC18A2, TH
Early endosome membrane 1 NTRK2
Multi-pass membrane protein 2 OPRD1, SLC18A2
Synapse 1 HCRT
glutamatergic synapse 1 GHRL
neuronal cell body 3 CALCA, GAL, MAOB
postsynapse 2 GHRL, HCRT
presynaptic membrane 1 OPRD1
smooth endoplasmic reticulum 1 TH
synaptic vesicle 4 HCRT, NGF, SLC18A2, TH
Cytoplasmic vesicle, secretory vesicle 1 NTS
plasma membrane 8 ENO2, F2, GAL, IFNLR1, NTRK2, OPRD1, PRKCQ, SLC18A2
synaptic vesicle membrane 2 OPRD1, SLC18A2
terminal bouton 4 CALCA, NTRK2, SLC18A2, TH
Membrane 5 ENO2, IFNLR1, NTRK2, OPRD1, SLC18A2
axon 5 GHRL, NGF, NTRK2, SLC18A2, TH
extracellular exosome 2 ENO2, F2
extracellular space 11 AVP, CALCA, ENO2, F2, GAL, GHRL, LEP, NGF, POMC, PPY, PRL
perinuclear region of cytoplasm 3 HCRT, NTRK2, TH
Schaffer collateral - CA1 synapse 1 GHRL
mitochondrion 2 MAOB, TH
intracellular membrane-bounded organelle 2 NTS, SLC18A2
postsynaptic density 1 NTRK2
Single-pass type I membrane protein 2 IFNLR1, NTRK2
Secreted 11 AVP, CALCA, F2, GAL, GHRL, LEP, NGF, NTS, POMC, PPY, PRL
extracellular region 12 AVP, CALCA, F2, GAL, GHRL, HCRT, LEP, NGF, NTS, POMC, PPY, PRL
cytoplasmic side of plasma membrane 1 TH
Mitochondrion outer membrane 1 MAOB
mitochondrial outer membrane 1 MAOB
hippocampal mossy fiber to CA3 synapse 1 CALCA
centriolar satellite 1 PRKCQ
photoreceptor inner segment 1 ENO2
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 SLC18A2
dendritic spine 1 NTRK2
neuronal dense core vesicle lumen 2 GHRL, HCRT
perikaryon 2 ENO2, TH
cytoplasmic vesicle 2 HCRT, TH
Melanosome membrane 1 TH
Early endosome 1 NTRK2
Cytoplasm, perinuclear region 2 NTRK2, TH
collagen-containing extracellular matrix 1 F2
secretory granule 3 AVP, GAL, POMC
receptor complex 1 NTRK2
neuron projection 2 OPRD1, TH
chromatin 1 PRL
blood microparticle 1 F2
endosome lumen 2 NGF, PRL
Cell projection, dendrite 2 NTRK2, SLC18A2
secretory granule lumen 2 GHRL, POMC
secretory granule membrane 1 SLC18A2
Golgi lumen 2 F2, NGF
endoplasmic reticulum lumen 2 F2, GHRL
axon terminus 3 NTRK2, NTS, OPRD1
transport vesicle 1 NTS
mitochondrial envelope 1 MAOB
postsynaptic density membrane 1 OPRD1
immunological synapse 1 PRKCQ
neuronal dense core vesicle 3 AVP, CALCA, OPRD1
aggresome 1 PRKCQ
Single-pass type IV membrane protein 1 MAOB
clathrin-coated endocytic vesicle membrane 1 AVP
dopaminergic synapse 1 SLC18A2
dendrite membrane 1 OPRD1
Cytoplasmic vesicle, secretory vesicle membrane 1 SLC18A2
Rough endoplasmic reticulum 1 HCRT
phosphopyruvate hydratase complex 1 ENO2
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
clathrin-sculpted monoamine transport vesicle membrane 1 SLC18A2
spine apparatus 1 OPRD1
interleukin-28 receptor complex 1 IFNLR1


文献列表

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  • Ru-Hong Tu, Sheng-Ze Wu, Ze-Ning Huang, Qing Zhong, Yin-Hua Ye, Chao-Hui Zheng, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Chang-Ming Huang, Mi Lin, Jun Lu, Long-Long Cao, Ping Li. Neurotransmitter Receptor HTR2B Regulates Lipid Metabolism to Inhibit Ferroptosis in Gastric Cancer. Cancer research. 2023 12; 83(23):3868-3885. doi: 10.1158/0008-5472.can-23-1012. [PMID: 38037454]
  • Yanrong Gong, Xiaoxia Liang, Yanting Dai, Xiang Huang, Qiaozhen Su, Yan Ma, Fenglian Chen, Shuling Wang. Prokinetic effects of Citrus reticulata and Citrus aurantium extract with/without Bupleurum chinense using multistress-induced delayed gastric emptying models. Pharmaceutical biology. 2023 Dec; 61(1):345-355. doi: 10.1080/13880209.2023.2173249. [PMID: 36728913]
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  • Chan Li, Yingbo Lin, Rukun Lin, Zhijie Chen, Qichun Zhou, Chaohua Luo, Zhixian Mo. Host miR-129-5p reverses effects of ginsenoside Rg1 on morphine reward possibly mediated by changes in B. vulgatus and serotonin metabolism in hippocampus. Gut microbes. 2023 12; 15(2):2254946. doi: 10.1080/19490976.2023.2254946. [PMID: 37698853]
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