Malaoxon (BioDeep_00000002240)
Secondary id: BioDeep_00001867741
human metabolite Endogenous blood metabolite
代谢物信息卡片
1,4-diethyl 2-[(dimethoxyphosphoryl)sulfanyl]butanedioate
化学式: C10H19O7PS (314.0589)
中文名称: 马拉氧磷
谱图信息:
最多检出来源 Homo sapiens(blood) 7.66%
分子结构信息
SMILES: CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC
InChI: InChI=1S/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3
描述信息
Malaoxon is a metabolite of malathion. Malaoxon is a chemical compound with the formula C10H19O7PS. More specifically, it is a phosphorothioate. It is a breakdown product of, and more toxic than, malathion. (Wikipedia)
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3713
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
22 个数据库交叉引用编号
- ChEBI: CHEBI:141477
- ChEBI: CHEBI:6649
- KEGG: C07498
- PubChem: 15415
- HMDB: HMDB0060627
- Metlin: METLIN1060
- ChEMBL: CHEMBL1331476
- Wikipedia: Malaoxon
- CAS: 1634-78-2
- MoNA: EQ371308
- MoNA: EQ371307
- MoNA: EQ371302
- MoNA: EQ371301
- MoNA: EQ371306
- MoNA: EQ371309
- MoNA: EQ371305
- MoNA: EQ371303
- MoNA: EQ371304
- PMhub: MS000002205
- PubChem: 9701
- NIKKAJI: J7.538H
- RefMet: Malaoxon
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zhou Tong, Yan Shen, DanDan Meng, XiaoTong Yi, MingNa Sun, Xu Dong, Yue Chu, JinSheng Duan. Ecological threat caused by malathion and its chiral metabolite in a honey bee-rape system: Stereoselective exposure risk and the mechanism revealed by proteome.
The Science of the total environment.
2023 Mar; 874(?):162585. doi:
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2020 Aug; 76(8):2557-2568. doi:
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Talanta.
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2010 Dec; 188(3):553-7. doi:
10.1016/j.cbi.2010.07.022. [PMID: 20692243] - Milica Zlatković, Miodrag Jovanović, Dragana Djordjević, Slavica Vucinić. [Rapid simultaneous determination of organophosphorus pesticides in human serum and urine by liquid chromatography-mass spectrometry].
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2010 Jan; 24(1):51-9. doi:
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2008 Sep; 175(1-3):376-9. doi:
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10.1191/096032799678839581. [PMID: 10602389] - M R Hirvonen, L Paljärvi, K M Savolainen. Malaoxon-induced neurotoxicity in old rats: alterations in cerebral inositol lipid signalling, brain tissue calcium levels and early neuronal injury.
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10.1016/0300-483x(93)90129-g. [PMID: 8497869] - C Morgade, A Barquet. Body distribution of malathion and its metabolites in a fatal poisoning by ingestion.
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