Oxyquinoline (BioDeep_00000002165)

   


代谢物信息卡片


8-HYDROXYQUINOLINE

化学式: C9H7NO (145.0527612)
中文名称: 8-羟基喹啉
谱图信息: 最多检出来源 Homo sapiens(plant) 30%

分子结构信息

SMILES: C1=CC2=C(C(=C1)O)N=CC=C2
InChI: InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

描述信息

G - Genito urinary system and sex hormones > G01 - Gynecological antiinfectives and antiseptics > G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids > G01AC - Quinoline derivatives
A - Alimentary tract and metabolism > A01 - Stomatological preparations > A01A - Stomatological preparations > A01AB - Antiinfectives and antiseptics for local oral treatment
D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AH - Quinoline derivatives
R - Respiratory system > R02 - Throat preparations > R02A - Throat preparations > R02AA - Antiseptics
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
CONFIDENCE standard compound; ML_ID 55

同义名列表

5 个代谢物同义名

8-HYDROXYQUINOLINE; Oxyquinoline; quinolin-8-ol; 8-Hydroxyquinoline; 8-Hydroxyquinoline



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(5)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Liping Li, Hao Wu, Jiayin Wang, Zhe Ji, Ting Fang, Hui Lu, Lan Yan, Fuming Shen, Dazhi Zhang, Yuanying Jiang, Tingjunhong Ni. Discovery of Novel 8-Hydroxyquinoline Derivatives with Potent In Vitro and In Vivo Antifungal Activity. Journal of medicinal chemistry. 2023 Dec; 66(23):16364-16376. doi: 10.1021/acs.jmedchem.3c01771. [PMID: 37975824]
  • Justyna Waśniowska, Teresa Leszczyńska, Aneta Kopeć, Ewa Piątkowska, Sylwester Smoleń, Joanna Krzemińska, Iwona Kowalska, Jacek Słupski, Ewelina Piasna-Słupecka, Katarzyna Krawczyk, Aneta Koronowicz. Curly Kale (Brassica oleracea var. Sabellica L.) Biofortified with 5,7-Diiodo-8-quinolinol: The Influence of Heat Treatment on Iodine Level, Macronutrient Composition and Antioxidant Content. Nutrients. 2023 Nov; 15(22):. doi: 10.3390/nu15224730. [PMID: 38004124]
  • Toshali Bhoyar, Devthade Vidyasagar, Suresh S Umare. Mitigating phytotoxicity of tetracycline by metal-free 8-hydroxyquinoline functionalized carbon nitride photocatalyst. Journal of environmental sciences (China). 2023 Mar; 125(?):37-46. doi: 10.1016/j.jes.2021.10.032. [PMID: 36375922]
  • Gonzalo Scalese, Zeyad Arhouma, Kateryna Kostenkova, Leticia Pérez-Díaz, Dean C Crick, Dinorah Gambino, Debbie C Crans. Do bioactive 8-hydroxyquinolines oxidovanadium(IV) and (V) complexes inhibit the growth of M. smegmatis?. Journal of inorganic biochemistry. 2022 12; 237(?):111984. doi: 10.1016/j.jinorgbio.2022.111984. [PMID: 36152468]
  • Shuzhe Wang, Yan Wang, Bohua Xu, Tian Qin, Yupeng Lv, Heng Yan, Yifei Shao, Yangyang Fang, Shaoqiu Zheng, Yunliang Qiu. Biodistribution of 89Zr-oxine-labeled human bone marrow-derived mesenchymal stem cells by micro-PET/computed tomography imaging in Sprague-Dawley rats. Nuclear medicine communications. 2022 Jul; 43(7):834-846. doi: 10.1097/mnm.0000000000001562. [PMID: 35438673]
  • Orsolya Dömötör, Bernhard K Keppler, Éva A Enyedy. Solution speciation and human serum protein binding of indium(III) complexes of 8-hydroxyquinoline, deferiprone and maltol. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2022 04; 27(3):315-328. doi: 10.1007/s00775-022-01935-6. [PMID: 35243522]
  • Tamás Pivarcsik, Orsolya Dömötör, János P Mészáros, Nóra V May, Gabriella Spengler, Oszkár Csuvik, István Szatmári, Éva A Enyedy. 8-Hydroxyquinoline-Amino Acid Hybrids and Their Half-Sandwich Rh and Ru Complexes: Synthesis, Anticancer Activities, Solution Chemistry and Interaction with Biomolecules. International journal of molecular sciences. 2021 Oct; 22(20):. doi: 10.3390/ijms222011281. [PMID: 34681939]
  • L M de Souza, M A de Chaves, A R Joaquim, M P Gionbelli, A Gava, J Fiorentin, E Ficagna, M A K Almança, M L Teixeira, S F Andrade, A M Fuentefria. The efficacy of 8-hydroxyquinoline derivatives in controlling the fungus Ilyonectria liriodendri, the causative agent of black foot disease in grapevines. Journal of applied microbiology. 2021 Sep; 131(3):1440-1451. doi: 10.1111/jam.15035. [PMID: 33565222]
  • Jean-Marc Riedinger, Matthieu Gallet, Alexandra Nicolas, Clément Drouet, Alexandre Cochet. [Factors influencing platelets labelling with indium-111 oxine]. Annales de biologie clinique. 2021 Aug; 79(4):339-344. doi: 10.1684/abc.2021.1666. [PMID: 34427559]
  • Cheng-Hsiu Lu, Yi-An Chen, Chien-Chih Ke, Sain-Jhih Chiu, Chao-Cheng Chen, Ya-Ju Hsieh, Bang-Hung Yang, Ren-Shyan Liu. Preclinical Characterization and In Vivo Imaging of 111In-Labeled Mesenchymal Stem Cell-Derived Extracellular Vesicles. Molecular imaging and biology. 2021 06; 23(3):361-371. doi: 10.1007/s11307-020-01562-0. [PMID: 33216285]
  • Arif Ali, Nasim Sepay, Mohd Afzal, Nayim Sepay, Abdullah Alarifi, M Shahid, Musheer Ahmad. Molecular designing, crystal structure determination and in silico screening of copper(II) complexes bearing 8-hydroxyquinoline derivatives as anti-COVID-19. Bioorganic chemistry. 2021 05; 110(?):104772. doi: 10.1016/j.bioorg.2021.104772. [PMID: 33676041]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Xiao-Dan Yin, Kun-Yuan Ma, Yu-Ling Wang, Yu Sun, Xiao-Fei Shang, Zhong-Min Zhao, Ren-Xuan Wang, Yong-Jia Chen, Jia-Kai Zhu, Ying-Qian Liu. Design, Synthesis, and Antifungal Evaluation of 8-Hydroxyquinoline Metal Complexes against Phytopathogenic Fungi. Journal of agricultural and food chemistry. 2020 Oct; 68(40):11096-11104. doi: 10.1021/acs.jafc.0c01322. [PMID: 32941027]
  • Fatemeh Mohammadi, Hassan Mansouri-Torshizi. Five novel palladium(II) complexes of 8-hydroxyquinoline and amino acids with hydrophobic side chains: synthesis, characterization, cytotoxicity, DNA- and BSA-interaction studies. Journal of biomolecular structure & dynamics. 2020 Jul; 38(10):3059-3073. doi: 10.1080/07391102.2019.1651219. [PMID: 31378152]
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  • Xiaozhu Wang, María de Guadalupe Jaraquemada-Peláez, Yang Cao, Jinhe Pan, Kuo-Shyan Lin, Brian O Patrick, Chris Orvig. H2hox: Dual-Channel Oxine-Derived Acyclic Chelating Ligand for 68Ga Radiopharmaceuticals. Inorganic chemistry. 2019 Feb; 58(4):2275-2285. doi: 10.1021/acs.inorgchem.8b01208. [PMID: 29989801]
  • Nasrin Abbasi Gharibkandi, Sajjad Molavipordanjani, Jafar Akbari, Seyed Jalal Hosseinimehr. Pharmacokinetic Evaluation of 99mTc-radiolabeled Solid Lipid Nanoparticles and Chitosan Coated Solid Lipid Nanoparticles. Current drug metabolism. 2019; 20(13):1044-1052. doi: 10.2174/1389200220666191112145808. [PMID: 31721707]
  • Vladimir Chobot, Franz Hadacek, Gert Bachmann, Wolfram Weckwerth, Lenka Kubicova. Antioxidant Properties and the Formation of Iron Coordination Complexes of 8-Hydroxyquinoline. International journal of molecular sciences. 2018 Dec; 19(12):. doi: 10.3390/ijms19123917. [PMID: 30544490]
  • Jakob Kljun, Ignacio E León, Špela Peršič, Juan F Cadavid-Vargas, Susana B Etcheverry, Weijiang He, Yang Bai, Iztok Turel. Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines. Journal of inorganic biochemistry. 2018 09; 186(?):187-196. doi: 10.1016/j.jinorgbio.2018.05.009. [PMID: 29960150]
  • Miroslav Vetrik, Jana Mattova, Hana Mackova, Jan Kucka, Pavla Pouckova, Olivia Kukackova, Jiri Brus, Sebastian Eigner-Henke, Ondrej Sedlacek, Ludek Sefc, Petr Stepanek, Martin Hruby. Biopolymer strategy for the treatment of Wilson's disease. Journal of controlled release : official journal of the Controlled Release Society. 2018 03; 273(?):131-138. doi: 10.1016/j.jconrel.2018.01.026. [PMID: 29407674]
  • Ashaparna Mondal, Sourav De, Santanu Maiti, Bidisha Sarkar, Ashok Kumar Sk, Rini Jacob, Anbalagan Moorthy, Priyankar Paira. Amberlite IR-120 (H) mediated 'on water' synthesis of fluorescent Ruthenium(II)-arene 8-hydroxyquinoline complexes for cancer therapy and live cell imaging. Journal of photochemistry and photobiology. B, Biology. 2018 Jan; 178(?):380-394. doi: 10.1016/j.jphotobiol.2017.11.033. [PMID: 29195215]
  • Haijiao Zheng, Tenggao Zhu, Xiqian Li, Guan Wang, Qiong Jia. Immobilization of β-Cyclodextrin-Conjugated Lactoferrin onto Polymer Monolith for Enrichment of Ga in Metabolic Residues of Ga-Based Anticancer Drugs. Biomacromolecules. 2017 Dec; 18(12):3971-3977. doi: 10.1021/acs.biomac.7b01003. [PMID: 29068673]
  • Mustafa Khan, Tasneem Gul Kazi, Hasan Imran Afridi, Muhammad Bilal, Asma Akhtar, Naeem Ullah, Sabir Khan, Sehrish Talpur. Application of ultrasonically modified cloud point extraction method for simultaneous enrichment of cadmium and lead in sera of different types of gallstone patients. Ultrasonics sonochemistry. 2017 Nov; 39(?):313-320. doi: 10.1016/j.ultsonch.2017.04.043. [PMID: 28732951]
  • Marketa Houdkova, Johana Rondevaldova, Ivo Doskocil, Ladislav Kokoska. Evaluation of antibacterial potential and toxicity of plant volatile compounds using new broth microdilution volatilization method and modified MTT assay. Fitoterapia. 2017 Apr; 118(?):56-62. doi: 10.1016/j.fitote.2017.02.008. [PMID: 28223069]
  • Banashree Deka, Tukki Sarkar, Samya Banerjee, Arun Kumar, Sanjoy Mukherjee, Sasanka Deka, Kandarpa K Saikia, Akhtar Hussain. Novel mitochondria targeted copper(ii) complexes of ferrocenyl terpyridine and anticancer active 8-hydroxyquinolines showing remarkable cytotoxicity, DNA and protein binding affinity. Dalton transactions (Cambridge, England : 2003). 2017 Jan; 46(2):396-409. doi: 10.1039/c6dt03660k. [PMID: 27929173]
  • Gaurav Malviya, Tapan Nayak, Christian Gerdes, Rudi A J O Dierckx, Alberto Signore, Erik F J de Vries. Isolation and (111)In-Oxine Labeling of Murine NK Cells for Assessment of Cell Trafficking in Orthotopic Lung Tumor Model. Molecular pharmaceutics. 2016 Apr; 13(4):1329-38. doi: 10.1021/acs.molpharmaceut.5b00947. [PMID: 26962716]
  • J Novakova, E Vlkova, H Salmonova, R Pechar, V Rada, L Kokoska. Anticlostridial agent 8-hydroxyquinoline improves the isolation of faecal bifidobacteria on modified Wilkins-Chalgren agar with mupirocin. Letters in applied microbiology. 2016 Apr; 62(4):330-5. doi: 10.1111/lam.12552. [PMID: 26849418]
  • Idrees Mohammed, Shahienaz E Hampton, Louise Ashall, Emily R Hildebrandt, Robert A Kutlik, Surya P Manandhar, Brandon J Floyd, Haley E Smith, Jonathan K Dozier, Mark D Distefano, Walter K Schmidt, Timothy M Dore. 8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells. Bioorganic & medicinal chemistry. 2016 Jan; 24(2):160-78. doi: 10.1016/j.bmc.2015.11.043. [PMID: 26706114]
  • Takehiko Matsuya, Yuichi Otsuka, Motohiro Tagaya, Satoshi Motozuka, Kiyoshi Ohnuma, Yoshiharu Mutoh. Formation of stacked luminescent complex of 8-hydroxyquinoline molecules on hydroxyapatite coating by using cold isostatic pressing. Materials science & engineering. C, Materials for biological applications. 2016 Jan; 58(?):127-32. doi: 10.1016/j.msec.2015.08.020. [PMID: 26478295]
  • Hossein Abdolmohammad-Zadeh, Elaheh Rahimpour. CoFe2O4 nano-particles functionalized with 8-hydroxyquinoline for dispersive solid-phase micro-extraction and direct fluorometric monitoring of aluminum in human serum and water samples. Analytica chimica acta. 2015 Jun; 881(?):54-64. doi: 10.1016/j.aca.2015.04.035. [PMID: 26041520]
  • Sonali M Shiriskar, Neeraj Agarwal, Raghuvir R S Pissurlenkar, Basir Ahmad. Effects of 2-amino-8-hydroxyquinoline interaction on the conformation of physiological isomers of human serum albumin. European biophysics journal : EBJ. 2015 May; 44(4):193-205. doi: 10.1007/s00249-015-1014-0. [PMID: 25761396]
  • Abdul Haleem Panhwar, Tasneem Gul Kazi, Hassan Imran Afridi, Salma Aslam Arain, Naeemullah, Kapil Dev Brahman, Mariam Shahzadi Arain. A new solid phase microextraction method using organic ligand in micropipette tip syringe system packed with modified carbon cloth for preconcentration of cadmium in drinking water and blood samples of kidney failure patients. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2015 Mar; 138(?):296-302. doi: 10.1016/j.saa.2014.11.059. [PMID: 25498826]
  • Mingming Zhao, Ruiren Tang, Shuai Xu. Investigations into the bovine serum albumin binding and fluorescence properties of Tb (III) complex of a novel 8-hydroxyquinoline ligand. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2015 Jan; 135(?):953-8. doi: 10.1016/j.saa.2014.07.089. [PMID: 25168232]
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  • Éva A Enyedy, Orsolya Dömötör, Krisztina Bali, Anasztázia Hetényi, Tiziano Tuccinardi, Bernhard K Keppler. Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2015 Jan; 20(1):77-88. doi: 10.1007/s00775-014-1211-9. [PMID: 25398250]
  • Benoît Nespola, Valérie Betz, Julie Brunet, Jean-Charles Gagnard, Yves Krummel, Yves Hansmann, Thierry Hannedouche, Daniel Christmann, Alexander W Pfaff, Denis Filisetti, Bernard Pesson, Ahmed Abou-Bacar, Ermanno Candolfi. First case of amebic liver abscess 22 years after the first occurrence. Parasite (Paris, France). 2015; 22(?):20. doi: 10.1051/parasite/2015020. [PMID: 26088504]
  • Davood Hashemabadi, Ali Mohammadi Torkashvand, Behzad Kaviani, Maryam Bagherzadeh, Mohaddeseh Rezaalipour, Mohammad Zarchini. Effect of Mentha pulegium extract and 8-hydroxy quinoline sulphate to extend the quality and vase life of rose (Rosa hybrid) cut flower. Journal of environmental biology. 2015 Jan; 36(1):215-20. doi: ". [PMID: 26536795]
  • V Thamilarasan, N Sengottuvelan, A Sudha, P Srinivasan, A Siva. Synthesis, molecular structure, theoretical calculation, DNA/protein interaction and cytotoxic activity of manganese(III) complex with 8-hydroxyquinoline. Journal of photochemistry and photobiology. B, Biology. 2015 Jan; 142(?):220-31. doi: 10.1016/j.jphotobiol.2014.12.001. [PMID: 25550122]
  • Jitka Novakova, Mária Džunková, Sarka Musilova, Eva Vlkova, Ladislav Kokoska, Andrés Moya, Giuseppe D'Auria. Selective growth-inhibitory effect of 8-hydroxyquinoline towards Clostridium difficile and Bifidobacterium longum subsp. longum in co-culture analysed by flow cytometry. Journal of medical microbiology. 2014 Dec; 63(Pt 12):1663-1669. doi: 10.1099/jmm.0.080796-0. [PMID: 25298160]
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