2-aminoacridone (BioDeep_00001876695)

Main id: BioDeep_00000009124

 


代谢物信息卡片


2-aminoacridone

化学式: C13H10N2O (210.0793)
中文名称: 2-氨基吖啶酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)C3=C(N2)C=CC(=C3)N
InChI: InChI=1S/C13H10N2O/c14-8-5-6-12-10(7-8)13(16)9-3-1-2-4-11(9)15-12/h1-7H,14H2,(H,15,16)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

3 个代谢物同义名

2-aminoacridone; AMAC; 2-Aminoacridone



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 ANPEP, CASP3, GCK
Peripheral membrane protein 1 GCK
Endosome membrane 2 PLD3, TF
Endoplasmic reticulum membrane 1 PLD3
Nucleus 4 CASP3, GCK, NCL, PPT1
cytosol 6 CASP3, GCK, LIPE, MB, PPT1, RPE
dendrite 1 PPT1
nucleoplasm 3 CASP3, GCK, NCL
Cell membrane 3 ANPEP, LIPE, TNF
Early endosome membrane 1 PLD3
Multi-pass membrane protein 1 SLC35G5
Golgi apparatus membrane 2 GCK, PLD3
Synapse 1 ACAN
cell cortex 1 NCL
cell surface 3 EPO, TF, TNF
glutamatergic synapse 2 ACAN, CASP3
Golgi apparatus 2 ATRN, PPT1
Golgi membrane 2 GCK, PLD3
lysosomal membrane 3 ANPEP, PLD3, PPT1
neuronal cell body 3 CASP3, PPT1, TNF
synaptic vesicle 1 PPT1
Cytoplasm, cytosol 1 LIPE
Lysosome 2 GALNS, PPT1
plasma membrane 5 ANPEP, ATRN, NCL, TF, TNF
synaptic vesicle membrane 1 PPT1
Membrane 5 LIPE, NCL, PLD3, PPT1, SLC35G5
apical plasma membrane 1 TF
axon 1 PPT1
basolateral plasma membrane 1 GCK
caveola 1 LIPE
extracellular exosome 11 ANPEP, ATRN, EPO, GALNS, MB, NCL, PLD3, PPT1, RPE, SMPDL3A, TF
extracellular space 8 ACAN, ANPEP, ATRN, EPO, SMPDL3A, TF, TG, TNF
lysosomal lumen 4 ACAN, GALNS, PLD3, PPT1
perinuclear region of cytoplasm 1 TF
mitochondrion 1 GCK
intracellular membrane-bounded organelle 1 PPT1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 ATRN
Secreted 6 EPO, IL23A, PPT1, SMPDL3A, TF, TG
extracellular region 8 ACAN, EPO, GALNS, IL23A, PPT1, TF, TG, TNF
basal part of cell 1 TF
[Isoform 2]: Secreted 1 ATRN
external side of plasma membrane 2 ANPEP, TNF
Secreted, extracellular space, extracellular matrix 1 ACAN
cytoplasmic vesicle 1 TF
nucleolus 1 NCL
sarcoplasm 1 MB
Early endosome 1 TF
clathrin-coated pit 1 TF
recycling endosome 2 TF, TNF
Single-pass type II membrane protein 3 ANPEP, PLD3, TNF
vesicle 1 TF
Membrane raft 2 PPT1, TNF
GABA-ergic synapse 1 ACAN
basement membrane 1 ACAN
collagen-containing extracellular matrix 1 ACAN
Late endosome 1 TF
Late endosome membrane 1 PLD3
phagocytic cup 1 TNF
Chromosome 1 NCL
cytoplasmic ribonucleoprotein granule 1 NCL
Nucleus, nucleolus 1 NCL
blood microparticle 1 TF
Basolateral cell membrane 1 GCK
spliceosomal complex 1 NCL
[Isoform 3]: Secreted 1 ATRN
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Cornified envelope 1 NCL
cell body 1 EPO
basal plasma membrane 1 TF
secretory granule lumen 2 EPO, TF
HFE-transferrin receptor complex 1 TF
secretory granule membrane 1 ANPEP
Golgi lumen 1 ACAN
endoplasmic reticulum lumen 2 IL23A, TF
endocytic vesicle 1 TF
azurophil granule lumen 1 GALNS
Lysosome lumen 1 PLD3
perineuronal net 1 ACAN
clathrin-coated endocytic vesicle membrane 1 TF
ribonucleoprotein complex 1 NCL
endoplasmic reticulum-Golgi intermediate compartment 1 ANPEP
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 ATRN
presynaptic cytosol 1 PPT1
vesicle coat 1 TF
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Cytoplasm, sarcoplasm 1 MB
macropinosome membrane 1 NCL
perisynaptic extracellular matrix 1 ACAN
interleukin-23 complex 1 IL23A
dense body 1 TF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Evgenia Karousou, Athanasia P Asimakopoulou, Vassiliki Zafeiropoulou, Manuela Viola, Luca Monti, Antonio Rossi, Alberto Passi, Nikos Karamanos. Fast screening of glycosaminoglycan disaccharides by fluorophore-assisted carbohydrate electrophoresis (FACE): applications to biologic samples and pharmaceutical formulations. Methods in molecular biology (Clifton, N.J.). 2015; 1229(?):143-59. doi: 10.1007/978-1-4939-1714-3_14. [PMID: 25325951]
  • Robert A M Vreeburg, Othman B Airianah, Stephen C Fry. Fingerprinting of hydroxyl radical-attacked polysaccharides by N-isopropyl-2-aminoacridone labelling. The Biochemical journal. 2014 Oct; 463(2):225-37. doi: 10.1042/bj20140678. [PMID: 25072268]
  • Ningguo Gao, Jie Shang, Dang Huynh, Vijaya L Manthati, Carolina Arias, Heather P Harding, Randal J Kaufman, Ian Mohr, David Ron, John R Falck, Mark A Lehrman. Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides. Molecular biology of the cell. 2011 Sep; 22(17):2994-3009. doi: 10.1091/mbc.e11-04-0286. [PMID: 21737679]
  • Martin Giera, Dick-Paul Kloos, Alex Raaphorst, Oleg A Mayboroda, André M Deelder, Henk Lingeman, Wilfried M A Niessen. Mild and selective labeling of malondialdehyde with 2-aminoacridone: assessment of urinary malondialdehyde levels. The Analyst. 2011 Jul; 136(13):2763-9. doi: 10.1039/c1an15254h. [PMID: 21611666]
  • Nicola Volpi. High-performance liquid chromatography and on-line mass spectrometry detection for the analysis of chondroitin sulfates/hyaluronan disaccharides derivatized with 2-aminoacridone. Analytical biochemistry. 2010 Feb; 397(1):12-23. doi: 10.1016/j.ab.2009.09.030. [PMID: 19769935]
  • Manuela Viola, Davide Vigetti, Evgenia Karousou, Barbara Bartolini, Anna Genasetti, Manuela Rizzi, Moira Clerici, Francesco Pallotti, Giancarlo De Luca, Alberto Passi. New electrophoretic and chromatographic techniques for analysis of heparin and heparan sulfate. Electrophoresis. 2008 Aug; 29(15):3168-74. doi: 10.1002/elps.200700855. [PMID: 18633938]
  • Eiki Maeda, Masatoshi Kataoka, Mami Hino, Kazuaki Kajimoto, Noritada Kaji, Manabu Tokeshi, Jun-Ichi Kido, Yasuo Shinohara, Yoshinobu Baba. Determination of human blood glucose levels using microchip electrophoresis. Electrophoresis. 2007 Aug; 28(16):2927-33. doi: 10.1002/elps.200600795. [PMID: 17640093]
  • Maria Militsopoulou, Fotini N Lamari, Anders Hjerpe, Nikos K Karamanos. Determination of twelve heparin- and heparan sulfate-derived disaccharides as 2-aminoacridone derivatives by capillary zone electrophoresis using ultraviolet and laser-induced fluorescence detection. Electrophoresis. 2002 Apr; 23(7-8):1104-9. doi: 10.1002/1522-2683(200204)23:7/8<1104::aid-elps1104>3.0.co;2-1. [PMID: 11981858]
  • J Charlwood, H Birrell, D Tolson, J Connelly, P Camilleri. Early indication of effects of puromycin aminonucleoside using a fluorimetric assay of 2-aminoacridone-derivatized carbohydrates in urine. Analytical biochemistry. 2000 Aug; 283(2):250-7. doi: 10.1006/abio.2000.4628. [PMID: 10906246]
  • N Miki, M Nagano, K Kuriyama. Catalase activates cerebral granylate cyclase in the presence of sodium azide. Biochemical and biophysical research communications. 1976 Oct; 72(3):952-9. doi: 10.1016/s0006-291x(76)80224-0. [PMID: 10917]