Tetrahydro-1,4-oxazine (BioDeep_00001871316)
Main id: BioDeep_00000003049
Volatile Flavor Compounds
代谢物信息卡片
化学式: C4H9NO (87.0684104)
中文名称: 吗啡啉, 吗啉
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1COCCN1
InChI: InChI=1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:34856
- KEGG: C14452
- PubChem: 8083
- DrugBank: DB13669
- ChEMBL: CHEMBL276518
- CAS: 110-91-8
- PubChem: 17395452
- PDB-CCD: 6LR
- NIKKAJI: J2.453H
- KNApSAcK: 34856
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Lin Zhang, Yuping Wei, Ye Tao, Suya Zhao, Xuyang Wei, Xiaoyan Yin, Suyao Liu, Qiuhong Niu. Molecular mechanism of the smart attack of pathogenic bacteria on nematodes.
Microbial biotechnology.
2020 05; 13(3):683-705. doi:
10.1111/1751-7915.13508
. [PMID: 31730281] - Mahboubeh Hosseini-Kharat, Rahmatollah Rahimi, Davit Zargarian, Zohreh Mehri Lighvan, Amir Abbas Momtazi-Borojeni, Tayebeh Sharifi, Elham Abdollahi, Hossein Tavakol, Tecush Mohammadi. Antiproliferative activity of morpholine-based compounds on MCF-7 breast cancer, colon carcinoma C26, and normal fibroblast NIH-3T3 cell lines and study of their binding affinity to calf thymus-DNA and bovine serum albumin.
Journal of biomolecular structure & dynamics.
2019 09; 37(14):3788-3802. doi:
10.1080/07391102.2018.1527724
. [PMID: 30277419] - Seyed Ali Hosseini, Mahboube Eslami Moghadam, Maryam Saeidifar, Ali Akbar Saboury. Biological effect and molecular docking of anticancer palladium and platinum complexes with morpholine dithiocarbamate on human serum albumin as a blood carrier protein.
Canadian journal of physiology and pharmacology.
2018 Dec; 96(12):1276-1285. doi:
10.1139/cjpp-2017-0693
. [PMID: 30278151] - Maria G Katselou, Alexios N Matralis, Angeliki P Kourounakis. Developing potential agents against atherosclerosis: Design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity.
European journal of medicinal chemistry.
2017 Sep; 138(?):748-760. doi:
10.1016/j.ejmech.2017.06.042
. [PMID: 28728107] - Marie Mardal, Emma Gracia-Lor, Svenja Leibnitz, Sara Castiglioni, Markus R Meyer. Toxicokinetics of new psychoactive substances: plasma protein binding, metabolic stability, and human phase I metabolism of the synthetic cannabinoid WIN 55,212-2 studied using in vitro tools and LC-HR-MS/MS.
Drug testing and analysis.
2016 Oct; 8(10):1039-1048. doi:
10.1002/dta.1938
. [PMID: 26810883] - Eleni M Ladopoulou, Alexios N Matralis, Anastasios Nikitakis, Angeliki P Kourounakis. Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution.
Bioorganic & medicinal chemistry.
2015 Nov; 23(21):7015-23. doi:
10.1016/j.bmc.2015.09.034
. [PMID: 26433631] - Radosław Starosta, Aleksandra Bykowska, Agnieszka Kyzioł, Michał Płotek, Magdalena Florek, Jarosław Król, Małgorzata Jeżowska-Bojczuk. Copper(I) (pseudo)halide complexes with neocuproine and aminomethylphosphines derived from morpholine and thiomorpholine - in vitro cytotoxic and antimicrobial activity and the interactions with DNA and serum albumins.
Chemical biology & drug design.
2013 Nov; 82(5):579-86. doi:
10.1111/cbdd.12187
. [PMID: 23841542] - Alexandra Boecke, Dirk Sieger, Cristian Dan Neacsu, Hamid Kashkar, Martin Krönke. Factor associated with neutral sphingomyelinase activity mediates navigational capacity of leukocytes responding to wounds and infection: live imaging studies in zebrafish larvae.
Journal of immunology (Baltimore, Md. : 1950).
2012 Aug; 189(4):1559-66. doi:
10.4049/jimmunol.1102207
. [PMID: 22802420] - Federica Vacondio, Claudia Silva, Lisa Flammini, Vigilio Ballabeni, Elisabetta Barocelli, Marco Mor. Brain pharmacokinetics of non-imidazole biphenyl H3 receptor antagonists: a liquid chromatography/electrospray-mass spectrometry and ex vivo binding study in rats.
Chemistry & biodiversity.
2012 Jul; 9(7):1231-9. doi:
10.1002/cbdv.201100242
. [PMID: 22782872] - Soi H Bui, Kirsty J McLean, Myles R Cheesman, Justin M Bradley, Stephen E J Rigby, Colin W Levy, David Leys, Andrew W Munro. Unusual spectroscopic and ligand binding properties of the cytochrome P450-flavodoxin fusion enzyme XplA.
The Journal of biological chemistry.
2012 Jun; 287(23):19699-714. doi:
10.1074/jbc.m111.319202
. [PMID: 22500029] - Ishrat Jabeen, Karin Pleban, Uwe Rinner, Peter Chiba, Gerhard F Ecker. Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.
Journal of medicinal chemistry.
2012 Apr; 55(7):3261-73. doi:
10.1021/jm201705f
. [PMID: 22452412] - J Luong, R A Shellie, H Cortes, R Gras, T Hayward. Ultra-trace level analysis of morpholine, cyclohexylamine, and diethylaminoethanol in steam condensate by gas chromatography with multi-mode inlet, and flame ionization detection.
Journal of chromatography. A.
2012 Mar; 1229(?):223-9. doi:
10.1016/j.chroma.2012.01.041
. [PMID: 22325017] - Ruina Gao, Liang Li, Cen Xie, Xingxing Diao, Dafang Zhong, Xiaoyan Chen. Metabolism and pharmacokinetics of morinidazole in humans: identification of diastereoisomeric morpholine N+-glucuronides catalyzed by UDP glucuronosyltransferase 1A9.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Mar; 40(3):556-67. doi:
10.1124/dmd.111.042689
. [PMID: 22184458] - Timo Friedrich, Aaron M Lambert, Mark A Masino, Gerald B Downes. Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease.
Disease models & mechanisms.
2012 Mar; 5(2):248-58. doi:
10.1242/dmm.008383
. [PMID: 22046030] - Astrid S Pfister, Kristina Tanneberger, Alexandra Schambony, Jürgen Behrens. Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.
The Journal of biological chemistry.
2012 Jan; 287(3):1734-41. doi:
10.1074/jbc.m111.308650
. [PMID: 22128170] - Oludotun Adebayo Phillips, Edet Ekpenyong Udo, Reny Varghese. Antimycobacterial Activities of Novel 5-(1H-1,2,3-Triazolyl)Methyl Oxazolidinones.
Tuberculosis research and treatment.
2012; 2012(?):289136. doi:
10.1155/2012/289136
. [PMID: 22577542] - David E Stec, Peter A Hosick, Joey P Granger. Bilirubin, renal hemodynamics, and blood pressure.
Frontiers in pharmacology.
2012; 3(?):18. doi:
10.3389/fphar.2012.00018
. [PMID: 22347861] - Cai-Rong Yang, Yanchang Wei, Shu-Tao Qi, Lei Chen, Qing-Hua Zhang, Jun-Yu Ma, Yi-Bo Luo, Ya-Peng Wang, Yi Hou, Heide Schatten, Zhong-Hua Liu, Qing-Yuan Sun. The G protein coupled receptor 3 is involved in cAMP and cGMP signaling and maintenance of meiotic arrest in porcine oocytes.
PloS one.
2012; 7(6):e38807. doi:
10.1371/journal.pone.0038807
. [PMID: 22685609] - Nelson W Chong, Andrea L Koekemoer, Samir Ounzain, Nilesh J Samani, Jordan T Shin, Stanley Y Shaw. STARS is essential to maintain cardiac development and function in vivo via a SRF pathway.
PloS one.
2012; 7(7):e40966. doi:
10.1371/journal.pone.0040966
. [PMID: 22815879] - Bai-Liang He, Ji-Min Yuan, Lu-Yun Yang, Jun-Feng Xie, Shao-Ping Weng, Xiao-Qiang Yu, Jian-Guo He. The viral TRAF protein (ORF111L) from infectious spleen and kidney necrosis virus interacts with TRADD and induces caspase 8-mediated apoptosis.
PloS one.
2012; 7(5):e37001. doi:
10.1371/journal.pone.0037001
. [PMID: 22615868] - Cristian Pattaro, Anna Köttgen, Alexander Teumer, Maija Garnaas, Carsten A Böger, Christian Fuchsberger, Matthias Olden, Ming-Huei Chen, Adrienne Tin, Daniel Taliun, Man Li, Xiaoyi Gao, Mathias Gorski, Qiong Yang, Claudia Hundertmark, Meredith C Foster, Conall M O'Seaghdha, Nicole Glazer, Aaron Isaacs, Ching-Ti Liu, Albert V Smith, Jeffrey R O'Connell, Maksim Struchalin, Toshiko Tanaka, Guo Li, Andrew D Johnson, Hinco J Gierman, Mary Feitosa, Shih-Jen Hwang, Elizabeth J Atkinson, Kurt Lohman, Marilyn C Cornelis, Åsa Johansson, Anke Tönjes, Abbas Dehghan, Vincent Chouraki, Elizabeth G Holliday, Rossella Sorice, Zoltan Kutalik, Terho Lehtimäki, Tõnu Esko, Harshal Deshmukh, Sheila Ulivi, Audrey Y Chu, Federico Murgia, Stella Trompet, Medea Imboden, Barbara Kollerits, Giorgio Pistis, Tamara B Harris, Lenore J Launer, Thor Aspelund, Gudny Eiriksdottir, Braxton D Mitchell, Eric Boerwinkle, Helena Schmidt, Margherita Cavalieri, Madhumathi Rao, Frank B Hu, Ayse Demirkan, Ben A Oostra, Mariza de Andrade, Stephen T Turner, Jingzhong Ding, Jeanette S Andrews, Barry I Freedman, Wolfgang Koenig, Thomas Illig, Angela Döring, H-Erich Wichmann, Ivana Kolcic, Tatijana Zemunik, Mladen Boban, Cosetta Minelli, Heather E Wheeler, Wilmar Igl, Ghazal Zaboli, Sarah H Wild, Alan F Wright, Harry Campbell, David Ellinghaus, Ute Nöthlings, Gunnar Jacobs, Reiner Biffar, Karlhans Endlich, Florian Ernst, Georg Homuth, Heyo K Kroemer, Matthias Nauck, Sylvia Stracke, Uwe Völker, Henry Völzke, Peter Kovacs, Michael Stumvoll, Reedik Mägi, Albert Hofman, Andre G Uitterlinden, Fernando Rivadeneira, Yurii S Aulchenko, Ozren Polasek, Nick Hastie, Veronique Vitart, Catherine Helmer, Jie Jin Wang, Daniela Ruggiero, Sven Bergmann, Mika Kähönen, Jorma Viikari, Tiit Nikopensius, Michael Province, Shamika Ketkar, Helen Colhoun, Alex Doney, Antonietta Robino, Franco Giulianini, Bernhard K Krämer, Laura Portas, Ian Ford, Brendan M Buckley, Martin Adam, Gian-Andri Thun, Bernhard Paulweber, Margot Haun, Cinzia Sala, Marie Metzger, Paul Mitchell, Marina Ciullo, Stuart K Kim, Peter Vollenweider, Olli Raitakari, Andres Metspalu, Colin Palmer, Paolo Gasparini, Mario Pirastu, J Wouter Jukema, Nicole M Probst-Hensch, Florian Kronenberg, Daniela Toniolo, Vilmundur Gudnason, Alan R Shuldiner, Josef Coresh, Reinhold Schmidt, Luigi Ferrucci, David S Siscovick, Cornelia M van Duijn, Ingrid Borecki, Sharon L R Kardia, Yongmei Liu, Gary C Curhan, Igor Rudan, Ulf Gyllensten, James F Wilson, Andre Franke, Peter P Pramstaller, Rainer Rettig, Inga Prokopenko, Jacqueline C M Witteman, Caroline Hayward, Paul Ridker, Afshin Parsa, Murielle Bochud, Iris M Heid, Wolfram Goessling, Daniel I Chasman, W H Linda Kao, Caroline S Fox. Genome-wide association and functional follow-up reveals new loci for kidney function.
PLoS genetics.
2012; 8(3):e1002584. doi:
10.1371/journal.pgen.1002584
. [PMID: 22479191] - Björn Hartleben, Eugen Widmeier, Nicola Wanner, Miriam Schmidts, Sung Tae Kim, Lisa Schneider, Britta Mayer, Dontscho Kerjaschki, Jeffrey H Miner, Gerd Walz, Tobias B Huber. Role of the polarity protein Scribble for podocyte differentiation and maintenance.
PloS one.
2012; 7(5):e36705. doi:
10.1371/journal.pone.0036705
. [PMID: 22586490] - Hanyong Chen, Ke Yao, Janos Nadas, Ann M Bode, Margarita Malakhova, Naomi Oi, Haitao Li, Ronald A Lubet, Zigang Dong. Prediction of molecular targets of cancer preventing flavonoid compounds using computational methods.
PloS one.
2012; 7(5):e38261. doi:
10.1371/journal.pone.0038261
. [PMID: 22693608] - J R Goldsmith, Christian Jobin. Think small: zebrafish as a model system of human pathology.
Journal of biomedicine & biotechnology.
2012; 2012(?):817341. doi:
10.1155/2012/817341
. [PMID: 22701308] - Alda Tufro. Morpholino-mediated gene knockdown in mammalian organ culture.
Methods in molecular biology (Clifton, N.J.).
2012; 886(?):305-9. doi:
10.1007/978-1-61779-851-1_27
. [PMID: 22639272] - Hong Wang, Sanna Lehtonen, Yu-Chia Chen, Eija Heikkilä, Pertti Panula, Harry Holthöfer. Neph3 associates with regulation of glomerular and neural development in zebrafish.
Differentiation; research in biological diversity.
2012 Jan; 83(1):38-46. doi:
10.1016/j.diff.2011.08.007
. [PMID: 22099175] - Hiroshi Yukiura, Kotaro Hama, Keita Nakanaga, Masayuki Tanaka, Yoichi Asaoka, Shinichi Okudaira, Naoaki Arima, Asuka Inoue, Takafumi Hashimoto, Hiroyuki Arai, Atsuo Kawahara, Hiroshi Nishina, Junken Aoki. Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish.
The Journal of biological chemistry.
2011 Dec; 286(51):43972-43983. doi:
10.1074/jbc.m111.301093
. [PMID: 21971049] - Chi-Ling Chiang, Swey-Shen Alex Chen, Shyh Jye Lee, Ku-Chi Tsao, Pei-Lun Chu, Cheng-Hao Wen, Shiaw-Min Hwang, Chao-Ling Yao, Hsinyu Lee. Lysophosphatidic acid induces erythropoiesis through activating lysophosphatidic acid receptor 3.
Stem cells (Dayton, Ohio).
2011 Nov; 29(11):1763-73. doi:
10.1002/stem.733
. [PMID: 21915944] - Qiaoli Li, Michael Frank, Masashi Akiyama, Hiroshi Shimizu, Shiu-Ying Ho, Christine Thisse, Bernard Thisse, Eli Sprecher, Jouni Uitto. Abca12-mediated lipid transport and Snap29-dependent trafficking of lamellar granules are crucial for epidermal morphogenesis in a zebrafish model of ichthyosis.
Disease models & mechanisms.
2011 Nov; 4(6):777-85. doi:
10.1242/dmm.007146
. [PMID: 21816950] - Yumei Xiao, Xiaoli Yang, Bo Li, Huizhu Yuan, Shuqing Wan, Yanjun Xu, Zhaohai Qin. Design, synthesis and antifungal/insecticidal evaluation of novel cinnamide derivatives.
Molecules (Basel, Switzerland).
2011 Oct; 16(11):8945-57. doi:
10.3390/molecules16118945
. [PMID: 22027951] - Ruxandra Bachmann-Gagescu, Ian G Phelps, George Stearns, Brian A Link, Susan E Brockerhoff, Cecilia B Moens, Dan Doherty. The ciliopathy gene cc2d2a controls zebrafish photoreceptor outer segment development through a role in Rab8-dependent vesicle trafficking.
Human molecular genetics.
2011 Oct; 20(20):4041-55. doi:
10.1093/hmg/ddr332
. [PMID: 21816947] - Ching-Ti Liu, Maija K Garnaas, Adrienne Tin, Anna Kottgen, Nora Franceschini, Carmen A Peralta, Ian H de Boer, Xiaoning Lu, Elizabeth Atkinson, Jingzhong Ding, Michael Nalls, Daniel Shriner, Josef Coresh, Abdullah Kutlar, Kirsten Bibbins-Domingo, David Siscovick, Ermeg Akylbekova, Sharon Wyatt, Brad Astor, Josef Mychaleckjy, Man Li, Muredach P Reilly, Raymond R Townsend, Adebowale Adeyemo, Alan B Zonderman, Mariza de Andrade, Stephen T Turner, Thomas H Mosley, Tamara B Harris, Charles N Rotimi, Yongmei Liu, Sharon L R Kardia, Michele K Evans, Michael G Shlipak, Holly Kramer, Michael F Flessner, Albert W Dreisbach, Wolfram Goessling, L Adrienne Cupples, W Linda Kao, Caroline S Fox. Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
PLoS genetics.
2011 Sep; 7(9):e1002264. doi:
10.1371/journal.pgen.1002264
. [PMID: 21931561] - Thiago F Borgati, Maria Amelia D Boaventura. Effects of indole amides on lettuce and onion germination and growth.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2011 Sep; 66(9-10):485-90. doi:
10.1515/znc-2011-9-1008
. [PMID: 22191214] - Paula Stein, Karen Schindler. Mouse oocyte microinjection, maturation and ploidy assessment.
Journal of visualized experiments : JoVE.
2011 Jul; ?(53):. doi:
10.3791/2851
. [PMID: 21808228] - Anke Ohler, Christoph Becker-Pauly. Morpholino knockdown of the ubiquitously expressed transmembrane serine protease TMPRSS4a in zebrafish embryos exhibits severe defects in organogenesis and cell adhesion.
Biological chemistry.
2011 Jul; 392(7):653-64. doi:
10.1515/bc.2011.070
. [PMID: 21657981] - Esther Kur, Anna Christa, Kerry N Veth, Chandresh R Gajera, Miguel A Andrade-Navarro, Jingjing Zhang, Jason R Willer, Ronald G Gregg, Salim Abdelilah-Seyfried, Sebastian Bachmann, Brian A Link, Annette Hammes, Thomas E Willnow. Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development.
Developmental dynamics : an official publication of the American Association of Anatomists.
2011 Jun; 240(6):1567-77. doi:
10.1002/dvdy.22624
. [PMID: 21455927] - Oni M Mapp, Gregory S Walsh, Cecilia B Moens, Masazumi Tada, Victoria E Prince. Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity.
Development (Cambridge, England).
2011 May; 138(10):2121-32. doi:
10.1242/dev.060442
. [PMID: 21521740] - T L Delatte, H Schluepmann, S C M Smeekens, G J de Jong, G W Somsen. Capillary electrophoresis-mass spectrometry analysis of trehalose-6-phosphate in Arabidopsis thaliana seedlings.
Analytical and bioanalytical chemistry.
2011 May; 400(4):1137-44. doi:
10.1007/s00216-011-4837-2
. [PMID: 21394451] - Davide Cacchiarelli, Ivano Legnini, Julie Martone, Valentina Cazzella, Adele D'Amico, Enrico Bertini, Irene Bozzoni. miRNAs as serum biomarkers for Duchenne muscular dystrophy.
EMBO molecular medicine.
2011 May; 3(5):258-65. doi:
10.1002/emmm.201100133
. [PMID: 21425469] - Ben Fogelgren, Shin-Yi Lin, Xiaofeng Zuo, Kimberly M Jaffe, Kwon Moo Park, Ryan J Reichert, P Darwin Bell, Rebecca D Burdine, Joshua H Lipschutz. The exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypes.
PLoS genetics.
2011 Apr; 7(4):e1001361. doi:
10.1371/journal.pgen.1001361
. [PMID: 21490950] - Masashi Akiyama. The roles of ABCA12 in keratinocyte differentiation and lipid barrier formation in the epidermis.
Dermato-endocrinology.
2011 Apr; 3(2):107-12. doi:
10.4161/derm.3.2.15136
. [PMID: 21695020] - Shuang Cui, Louis M Capecci, Randolph P Matthews. Disruption of planar cell polarity activity leads to developmental biliary defects.
Developmental biology.
2011 Mar; 351(2):229-41. doi:
10.1016/j.ydbio.2010.12.041
. [PMID: 21215262] - Robert J Gasperini, Xu Hou, Helena Parkington, Harry Coleman, David W Klaver, Adele J Vincent, Lisa C Foa, David H Small. TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons.
Molecular neurodegeneration.
2011 Mar; 6(1):19. doi:
10.1186/1750-1326-6-19
. [PMID: 21375738] - Esther J Pearl, Zeina Jarikji, Marko E Horb. Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes.
Developmental biology.
2011 Mar; 351(1):135-45. doi:
10.1016/j.ydbio.2010.12.043
. [PMID: 21215266] - Renzhi Han. Muscle membrane repair and inflammatory attack in dysferlinopathy.
Skeletal muscle.
2011 Mar; 1(1):10. doi:
10.1186/2044-5040-1-10
. [PMID: 21798087] - Eamon Dubaissi, Nancy Papalopulu. Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease.
Disease models & mechanisms.
2011 Mar; 4(2):179-92. doi:
10.1242/dmm.006494
. [PMID: 21183475] - Seok-Hyung Kim, Christina K Speirs, Lilianna Solnica-Krezel, Kevin C Ess. Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin.
Disease models & mechanisms.
2011 Mar; 4(2):255-67. doi:
10.1242/dmm.005587
. [PMID: 20959633] - Bo Wu, Bin Xiao, Caryn Cloer, Mona Shaban, Arpana Sali, Peijuan Lu, Juan Li, Kanneboyina Nagaraju, Xiao Xiao, Qi Long Lu. One-year treatment of morpholino antisense oligomer improves skeletal and cardiac muscle functions in dystrophic mdx mice.
Molecular therapy : the journal of the American Society of Gene Therapy.
2011 Mar; 19(3):576-83. doi:
10.1038/mt.2010.288
. [PMID: 21179007] - Poonam Yadav, Nalini V Purohit. Synthesis and biological evaluation of some novel 3,4-disubstituted isocoumarins.
Indian journal of pharmaceutical sciences.
2011 Mar; 73(2):171-8. doi:
10.4103/0250-474x.91586
. [PMID: 22303060] - Christiane Drews, Sabine Senkel, Gerhart U Ryffel. The nephrogenic potential of the transcription factors osr1, osr2, hnf1b, lhx1 and pax8 assessed in Xenopus animal caps.
BMC developmental biology.
2011 Jan; 11(?):5. doi:
10.1186/1471-213x-11-5
. [PMID: 21281489] - Naoki Ichikawa-Tomikawa, Kotaro Sugimoto, Seiro Satohisa, Keisuke Nishiura, Hideki Chiba. Possible involvement of tight junctions, extracellular matrix and nuclear receptors in epithelial differentiation.
Journal of biomedicine & biotechnology.
2011; 2011(?):253048. doi:
10.1155/2011/253048
. [PMID: 22162632] - Aurélie Clément, Lilianna Solnica-Krezel, Kathleen L Gould. The Cdc14B phosphatase contributes to ciliogenesis in zebrafish.
Development (Cambridge, England).
2011 Jan; 138(2):291-302. doi:
10.1242/dev.055038
. [PMID: 21177342] - A P Kourounakis, M G Katselou, A N Matralis, E M Ladopoulou, E Bavavea. Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents.
Current medicinal chemistry.
2011; 18(29):4418-39. doi:
10.2174/092986711797287557
. [PMID: 21864285] - Tomokazu Kawashima, Frederic Berger. Green love talks; cell-cell communication during double fertilization in flowering plants.
AoB PLANTS.
2011; 2011(?):plr015. doi:
10.1093/aobpla/plr015
. [PMID: 22476485] - Bo Zhang, Uyen Tran, Oliver Wessely. Expression of Wnt signaling components during Xenopus pronephros development.
PloS one.
2011; 6(10):e26533. doi:
10.1371/journal.pone.0026533
. [PMID: 22028899] - Emily G Notch, Joseph R Shaw, Bonita A Coutermarsh, Marisa Dzioba, Bruce A Stanton. Morpholino gene knockdown in adult Fundulus heteroclitus: role of SGK1 in seawater acclimation.
PloS one.
2011; 6(12):e29462. doi:
10.1371/journal.pone.0029462
. [PMID: 22216285] - Jade Li, Zhaoxia Sun. Qilin is essential for cilia assembly and normal kidney development in zebrafish.
PloS one.
2011; 6(11):e27365. doi:
10.1371/journal.pone.0027365
. [PMID: 22102889] - Renfang Song, Ihor V Yosypiv. (Pro)renin Receptor in Kidney Development and Disease.
International journal of nephrology.
2011; 2011(?):247048. doi:
10.4061/2011/247048
. [PMID: 21755055] - S J Shuttleworth, F A Silva, A R L Cecil, C D Tomassi, T J Hill, F I Raynaud, P A Clarke, P Workman. Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors.
Current medicinal chemistry.
2011; 18(18):2686-714. doi:
10.2174/092986711796011229
. [PMID: 21649578] - Takehiko Shiraishi, Peter E Nielsen. Improved cellular uptake of antisense peptide nucleic acids by conjugation to a cell-penetrating peptide and a lipid domain.
Methods in molecular biology (Clifton, N.J.).
2011; 751(?):209-21. doi:
10.1007/978-1-61779-151-2_13
. [PMID: 21674333] - Linda Z Holland, Takayuki Onai. Analyses of gene function in amphioxus embryos by microinjection of mRNAs and morpholino oligonucleotides.
Methods in molecular biology (Clifton, N.J.).
2011; 770(?):423-38. doi:
10.1007/978-1-61779-210-6_16
. [PMID: 21805274] - Bluma Linkowski Faintuch, Gustavo Eutimio Fernandez Núñez, Rodrigo Teodoro, Ana M Moro, Jair Mengatti. Radiolabeled nano-peptides show specificity for an animal model of human PC3 prostate cancer cells.
Clinics (Sao Paulo, Brazil).
2011; 66(2):327-36. doi:
10.1590/s1807-59322011000200024
. [PMID: 21484054] - Jaana Hyvärinen, Mataleena Parikka, Raija Sormunen, Mika Rämet, Karl Tryggvason, Kari I Kivirikko, Johanna Myllyharju, Peppi Koivunen. Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function.
The Journal of biological chemistry.
2010 Dec; 285(53):42023-32. doi:
10.1074/jbc.m110.145904
. [PMID: 20952382] - Asitha T Silva, Alien Nguyen, Changming Ye, Jeanmarie Verchot, Joong Ho Moon. Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts.
BMC plant biology.
2010 Dec; 10(?):291. doi:
10.1186/1471-2229-10-291
. [PMID: 21192827] - David E Saslowsky, Jin Ah Cho, Himani Chinnapen, Ramiro H Massol, Daniel J-F Chinnapen, Jessica S Wagner, Heidi E De Luca, Wendy Kam, Barry H Paw, Wayne I Lencer. Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2.
The Journal of clinical investigation.
2010 Dec; 120(12):4399-4409. doi:
10.1172/jci42958
. [PMID: 21041954] - Michael R Elizondo, Erine H Budi, David M Parichy. trpm7 regulation of in vivo cation homeostasis and kidney function involves stanniocalcin 1 and fgf23.
Endocrinology.
2010 Dec; 151(12):5700-9. doi:
10.1210/en.2010-0853
. [PMID: 20881241] - Alba Diz-Muñoz, Michael Krieg, Martin Bergert, Itziar Ibarlucea-Benitez, Daniel J Muller, Ewa Paluch, Carl-Philipp Heisenberg. Control of directed cell migration in vivo by membrane-to-cortex attachment.
PLoS biology.
2010 Nov; 8(11):e1000544. doi:
10.1371/journal.pbio.1000544
. [PMID: 21151339] - Qiaoli Li, Sara Sadowski, Michael Frank, Chunli Chai, Andras Váradi, Shiu-Ying Ho, Hong Lou, Michael Dean, Christine Thisse, Bernard Thisse, Jouni Uitto. The abcc6a gene expression is required for normal zebrafish development.
The Journal of investigative dermatology.
2010 Nov; 130(11):2561-8. doi:
10.1038/jid.2010.174
. [PMID: 20596085] - Nobuyuki Itoh. Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease.
Cell and tissue research.
2010 Oct; 342(1):1-11. doi:
10.1007/s00441-010-1024-2
. [PMID: 20730630] - Célia Ferreira, Sónia Silva, Fábio Faria-Oliveira, Eva Pinho, Mariana Henriques, Cândida Lucas. Candida albicans virulence and drug-resistance requires the O-acyltransferase Gup1p.
BMC microbiology.
2010 Sep; 10(?):238. doi:
10.1186/1471-2180-10-238
. [PMID: 20843317] - Sharon Ashworth, Beina Teng, Jessica Kaufeld, Emily Miller, Irini Tossidou, Christoph Englert, Frank Bollig, Lynne Staggs, Ian S D Roberts, Joon-Keun Park, Hermann Haller, Mario Schiffer. Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans.
PloS one.
2010 Sep; 5(9):e12626. doi:
10.1371/journal.pone.0012626
. [PMID: 20838616] - George Zanazzi, Gary Matthews. Enrichment and differential targeting of complexins 3 and 4 in ribbon-containing sensory neurons during zebrafish development.
Neural development.
2010 Sep; 5(?):24. doi:
10.1186/1749-8104-5-24
. [PMID: 20809954] - Eriko Avsar-Ban, Hisayoshi Ishikawa, Hiroshi Manya, Masatoki Watanabe, Shinichi Akiyama, Hideo Miyake, Tamao Endo, Yutaka Tamaru. Protein O-mannosylation is necessary for normal embryonic development in zebrafish.
Glycobiology.
2010 Sep; 20(9):1089-102. doi:
10.1093/glycob/cwq069
. [PMID: 20466645] - Murli Manohar, Hui Mei, Andrew J Franklin, Elly M Sweet, Toshiro Shigaki, Bruce B Riley, Colin W Macdiarmid, Kendal Hirschi. Zebrafish (Danio rerio) endomembrane antiporter similar to a yeast cation/H(+) transporter is required for neural crest development.
Biochemistry.
2010 Aug; 49(31):6557-66. doi:
10.1021/bi100362k
. [PMID: 20578725] - Jianyin Long, Yin Wang, Wenjian Wang, Benny H J Chang, Farhad R Danesh. Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions.
The Journal of biological chemistry.
2010 Jul; 285(30):23457-65. doi:
10.1074/jbc.m110.136168
. [PMID: 20501654] - Elke Neumann-Haefelin, Albrecht Kramer-Zucker, Krasimir Slanchev, Björn Hartleben, Foteini Noutsou, Katrin Martin, Nicola Wanner, Alexander Ritter, Markus Gödel, Philip Pagel, Xiao Fu, Alexandra Müller, Ralf Baumeister, Gerd Walz, Tobias B Huber. A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis.
Human molecular genetics.
2010 Jun; 19(12):2347-59. doi:
10.1093/hmg/ddq108
. [PMID: 20233749] - Krishna Prasadan, Sidhartha Tulachan, Ping Guo, Chiyo Shiota, Sohail Shah, George Gittes. Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression.
Biochemical and biophysical research communications.
2010 Jun; 396(4):1036-41. doi:
10.1016/j.bbrc.2010.05.058
. [PMID: 20471370] - László G Puskás, Liliána Z Fehér, Csaba Vizler, Ferhan Ayaydin, Erzsébet Rásó, Eszter Molnár, István Magyary, Iván Kanizsai, Márió Gyuris, Ramóna Madácsi, Gabriella Fábián, Klaudia Farkas, Péter Hegyi, Ferenc Baska, Béla Ozsvári, Klára Kitajka. Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells.
Lipids in health and disease.
2010 Jun; 9(?):56. doi:
10.1186/1476-511x-9-56
. [PMID: 20525221] - Jeffrey T White, Bo Zhang, Débora M Cerqueira, Uyen Tran, Oliver Wessely. Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus.
Development (Cambridge, England).
2010 Jun; 137(11):1863-73. doi:
10.1242/dev.042887
. [PMID: 20431116] - Neelakanteswar Aluru, John F Leatherland, Mathilakath M Vijayan. Bisphenol A in oocytes leads to growth suppression and altered stress performance in juvenile rainbow trout.
PloS one.
2010 May; 5(5):e10741. doi:
10.1371/journal.pone.0010741
. [PMID: 20505776] - Darryl Y Nishimura, Lisa M Baye, Rahat Perveen, Charles C Searby, Almudena Avila-Fernandez, Ines Pereiro, Carmen Ayuso, Diana Valverde, Paul N Bishop, Forbes D C Manson, Jill Urquhart, Edwin M Stone, Diane C Slusarski, Graeme C M Black, Val C Sheffield. Discovery and functional analysis of a retinitis pigmentosa gene, C2ORF71.
American journal of human genetics.
2010 May; 86(5):686-95. doi:
10.1016/j.ajhg.2010.03.005
. [PMID: 20398886] - Myoung Shin Kim, Seung Kew Yoon, Frank Bollig, Jirouta Kitagaki, Wonhee Hur, Nathan J Whye, Yun-Ping Wu, Miguel N Rivera, Jik Young Park, Ho-Shik Kim, Karim Malik, Daphne W Bell, Christoph Englert, Alan O Perantoni, Sean Bong Lee. A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway.
The Journal of biological chemistry.
2010 May; 285(19):14585-93. doi:
10.1074/jbc.m109.094334
. [PMID: 20220130] - Xiao-Gang Tong, Li-Li Zhou, Yue-Hu Wang, Chengfeng Xia, Ye Wang, Min Liang, Fan-Fan Hou, Yong-Xian Cheng. Acortatarins A and B, two novel antioxidative spiroalkaloids with a naturally unusual morpholine motif from Acorus tatarinowii.
Organic letters.
2010 Apr; 12(8):1844-7. doi:
10.1021/ol100451p
. [PMID: 20329735] - Frédérique van Holthoon, Patrick P J Mulder, Eric O van Bennekom, Henri Heskamp, Tina Zuidema, Hans J A van Rhijn. Quantitative analysis of penicillins in porcine tissues, milk and animal feed using derivatisation with piperidine and stable isotope dilution liquid chromatography tandem mass spectrometry.
Analytical and bioanalytical chemistry.
2010 Apr; 396(8):3027-40. doi:
10.1007/s00216-010-3523-0
. [PMID: 20186537] - Emilie Combet, Tom Preston, Kenneth E L McColl. Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation.
Rapid communications in mass spectrometry : RCM.
2010 Mar; 24(5):529-34. doi:
10.1002/rcm.4388
. [PMID: 20112267] - Scott J Balsitis, Katherine L Williams, Ruben Lachica, Diana Flores, Jennifer L Kyle, Erin Mehlhop, Syd Johnson, Michael S Diamond, P Robert Beatty, Eva Harris. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification.
PLoS pathogens.
2010 Feb; 6(2):e1000790. doi:
10.1371/journal.ppat.1000790
. [PMID: 20168989] - Ulrike Naumann, Elisabetta Cameroni, Monika Pruenster, Harsha Mahabaleshwar, Erez Raz, Hans-Günter Zerwes, Antal Rot, Marcus Thelen. CXCR7 functions as a scavenger for CXCL12 and CXCL11.
PloS one.
2010 Feb; 5(2):e9175. doi:
10.1371/journal.pone.0009175
. [PMID: 20161793] - Nicholas Matluk, Jennifer A Rochira, Aldona Karaczyn, Tamara Adams, Joseph M Verdi. A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway.
BMC biology.
2010 Jan; 8(?):7. doi:
10.1186/1741-7007-8-7
. [PMID: 20100315] - E A Rekka, P N Kourounakis. Medicinal chemistry of 2,2,4-substituted morpholines.
Current medicinal chemistry.
2010; 17(29):3422-30. doi:
10.2174/092986710793176276
. [PMID: 20712564] - Hideo Sugita, Shin'ichi Takeda. Progress in muscular dystrophy research with special emphasis on gene therapy.
Proceedings of the Japan Academy. Series B, Physical and biological sciences.
2010; 86(7):748-56. doi:
10.2183/pjab.86.748
. [PMID: 20689232] - Thomas W Sturgill, Michael N Hall. Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha.
ACS chemical biology.
2009 Dec; 4(12):999-1015. doi:
10.1021/cb900193e
. [PMID: 19902965] - Hui Ma, Trevor Blake, Ajay Chitnis, Paul Liu, Tamas Balla. Crucial role of phosphatidylinositol 4-kinase IIIalpha in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling.
Journal of cell science.
2009 Dec; 122(Pt 23):4303-10. doi:
10.1242/jcs.057646
. [PMID: 19887586] - Krishnamurthy Konduru, Siham M Nakamura, Gerardo G Kaplan. Hepatitis A virus (HAV) packaging size limit.
Virology journal.
2009 Nov; 6(?):204. doi:
10.1186/1743-422x-6-204
. [PMID: 19922643] - M M Löwik, P J Groenen, E N Levtchenko, L A Monnens, L P van den Heuvel. Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review.
European journal of pediatrics.
2009 Nov; 168(11):1291-304. doi:
10.1007/s00431-009-1017-x
. [PMID: 19562370] - Wei Song, Deepthi Pabbisetty, Elizabeth A Groeber, Rick C Steenwyk, Douglas M Fast. Comparison of fused-core and conventional particle size columns by LC-MS/MS and UV: application to pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis.
2009 Oct; 50(3):491-500. doi:
10.1016/j.jpba.2009.05.011
. [PMID: 19540084] - Richard W Naylor, Robert J Collins, Anna Philpott, Elizabeth A Jones. Normal levels of p27 are necessary for somite segmentation and determining pronephric organ size.
Organogenesis.
2009 Oct; 5(4):201-10. doi:
10.4161/org.5.4.9973
. [PMID: 20539739] - M Bayaa, B Vulesevic, A Esbaugh, M Braun, M E Ekker, M Grosell, S F Perry. The involvement of SLC26 anion transporters in chloride uptake in zebrafish (Danio rerio) larvae.
The Journal of experimental biology.
2009 Oct; 212(Pt 20):3283-95. doi:
10.1242/jeb.033910
. [PMID: 19801433] - Caroline R Sussman, Jinhua Zhao, Consuelo Plata, Jing Lu, Christopher Daly, Nathan Angle, Jennifer DiPiero, Iain A Drummond, Jennifer O Liang, Walter F Boron, Michael F Romero, Min-Hwang Chang. Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish.
American journal of physiology. Cell physiology.
2009 Oct; 297(4):C865-75. doi:
10.1152/ajpcell.00679.2008
. [PMID: 19625604] - Yvonne A R White, Joshua T Kyle, Antony W Wood. Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor II signaling.
Endocrinology.
2009 Sep; 150(9):4366-75. doi:
10.1210/en.2009-0356
. [PMID: 19443571]