Vinyl ether (BioDeep_00001868292)
Main id: BioDeep_00000011851
代谢物信息卡片
Vinyl ether
化学式: C4H6O (70.0419)
中文名称: 乙烯醚, 乙烯基醚
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=COC=C
InChI: InChI=1S/C4H6O/c1-3-5-4-2/h3-4H,1-2H2
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics
N - Nervous system > N01 - Anesthetics > N01A - Anesthetics, general > N01AA - Ethers
同义名列表
3 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:81293
- KEGG: C17721
- PubChem: 8024
- DrugBank: DB13690
- ChEMBL: CHEMBL2105883
- CAS: 9003-19-4
- CAS: 109-93-3
- PubChem: 96024051
- NIKKAJI: J2.441D
- KNApSAcK: 81293
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Marcos A Perez, Andrea J Clostio, Isabel R Houston, Jimena Ruiz, Leslie Magtanong, Scott J Dixon, Jennifer L Watts. Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity.
PLoS genetics.
2022 09; 18(9):e1010436. doi:
10.1371/journal.pgen.1010436. [PMID: 36178986] - Ernst R Werner, Markus A Keller, Sabrina Sailer, Katharina Lackner, Jakob Koch, Martin Hermann, Stefan Coassin, Georg Golderer, Gabriele Werner-Felmayer, Raphael A Zoeller, Nicolas Hulo, Johannes Berger, Katrin Watschinger. The TMEM189 gene encodes plasmanylethanolamine desaturase which introduces the characteristic vinyl ether double bond into plasmalogens.
Proceedings of the National Academy of Sciences of the United States of America.
2020 04; 117(14):7792-7798. doi:
10.1073/pnas.1917461117. [PMID: 32209662] - Wedad Fallatah, Tara Smith, Wei Cui, Dushmanthi Jayasinghe, Erminia Di Pietro, Shawn A Ritchie, Nancy Braverman. Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata.
Disease models & mechanisms.
2020 01; 13(1):. doi:
10.1242/dmm.042499. [PMID: 31862688] - Howard Goldfine. Cytochrome c takes on plasmalogen catabolism.
The Journal of biological chemistry.
2018 06; 293(22):8710-8711. doi:
10.1074/jbc.h118.003072. [PMID: 29858391] - Ernst R Werner, Markus A Keller, Sabrina Sailer, Daniele Seppi, Georg Golderer, Gabriele Werner-Felmayer, Raphael A Zoeller, Katrin Watschinger. A novel assay for the introduction of the vinyl ether double bond into plasmalogens using pyrene-labeled substrates.
Journal of lipid research.
2018 05; 59(5):901-909. doi:
10.1194/jlr.d080283. [PMID: 29540573] - Fernando Martínez-Montañés, Museer A Lone, Fong-Fu Hsu, Roger Schneiter. Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether.
Journal of lipid research.
2016 11; 57(11):2040-2050. doi:
10.1194/jlr.m070748. [PMID: 27561298] - Svetlana S Gorina, Yana Y Toporkova, Lucia S Mukhtarova, Elena O Smirnova, Ivan R Chechetkin, Bulat I Khairutdinov, Yuri V Gogolev, Alexander N Grechkin. Oxylipin biosynthesis in spikemoss Selaginella moellendorffii: Molecular cloning and identification of divinyl ether synthases CYP74M1 and CYP74M3.
Biochimica et biophysica acta.
2016 Apr; 1861(4):301-9. doi:
10.1016/j.bbalip.2016.01.001. [PMID: 26776054] - Anna V Ogorodnikova, Fakhima K Mukhitova, Alexander N Grechkin. Oxylipins in the spikemoss Selaginella martensii: Detection of divinyl ethers, 12-oxophytodienoic acid and related cyclopentenones.
Phytochemistry.
2015 Oct; 118(?):42-50. doi:
10.1016/j.phytochem.2015.08.003. [PMID: 26277770] - Xiaoyun Zhang, Ting Dong, Qiang Li, Xiaohui Liu, Lin Li, She Chen, Xiaoguang Lei. Second Generation TQ-Ligation for Cell Organelle Imaging.
ACS chemical biology.
2015 Jul; 10(7):1676-83. doi:
10.1021/acschembio.5b00193. [PMID: 25901763] - Kui Yang, Christopher M Jenkins, Beverly Dilthey, Richard W Gross. Multidimensional mass spectrometry-based shotgun lipidomics analysis of vinyl ether diglycerides.
Analytical and bioanalytical chemistry.
2015 Jul; 407(17):5199-210. doi:
10.1007/s00216-015-8640-3. [PMID: 25822162] - Gabriele Quandt, Georg Höfner, Klaus T Wanner. Synthesis and evaluation of N-substituted nipecotic acid derivatives with an unsymmetrical bis-aromatic residue attached to a vinyl ether spacer as potential GABA uptake inhibitors.
Bioorganic & medicinal chemistry.
2013 Jun; 21(11):3363-78. doi:
10.1016/j.bmc.2013.02.056. [PMID: 23598250] - Junhwa Shin, Pochi Shum, Jessica Grey, Shin-ichi Fujiwara, Guarov S Malhotra, Andres González-Bonet, Seok-Hee Hyun, Elaine Moase, Theresa M Allen, David H Thompson. Acid-labile mPEG-vinyl ether-1,2-dioleylglycerol lipids with tunable pH sensitivity: synthesis and structural effects on hydrolysis rates, DOPE liposome release performance, and pharmacokinetics.
Molecular pharmaceutics.
2012 Nov; 9(11):3266-76. doi:
10.1021/mp300326z. [PMID: 23030381] - Hee-Kwon Kim, Jeroen Van den Bossche, Seok-Hee Hyun, David H Thompson. Acid-triggered release via dePEGylation of fusogenic liposomes mediated by heterobifunctional phenyl-substituted vinyl ethers with tunable pH-sensitivity.
Bioconjugate chemistry.
2012 Oct; 23(10):2071-7. doi:
10.1021/bc300266y. [PMID: 22988941] - Takako Aboshi, Ritsuo Nishida, Naoki Mori. Identification of plasmalogen in the gut of silkworm (Bombyx mori).
Insect biochemistry and molecular biology.
2012 Aug; 42(8):596-601. doi:
10.1016/j.ibmb.2012.04.006. [PMID: 22580185] - Pan Liu, Jin Li, Jianping Liu, Jikun Yang, Yongqing Fan. Release behavior of tanshinone IIA sustained-release pellets based on crack formation theory.
Journal of pharmaceutical sciences.
2012 Aug; 101(8):2811-20. doi:
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Journal of plant physiology.
2012 Jul; 169(11):1090-101. doi:
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PloS one.
2012; 7(4):e35102. doi:
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International journal of molecular sciences.
2012; 13(1):540-551. doi:
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Langmuir : the ACS journal of surfaces and colloids.
2011 Dec; 27(23):14570-80. doi:
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BMC genomics.
2011 Oct; 12(?):514. doi:
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Biomacromolecules.
2011 Oct; 12(10):3581-91. doi:
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Chemistry and physics of lipids.
2011 Sep; 164(6):573-89. doi:
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Acta neuropathologica.
2011 Sep; 122(3):271-83. doi:
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Plant, cell & environment.
2011 Sep; 34(9):1507-20. doi:
10.1111/j.1365-3040.2011.02348.x. [PMID: 21554327] - Guanghou Shui, Jeffrey William Stebbins, Buu Duyen Lam, Wei Fun Cheong, Sin Man Lam, Francine Gregoire, Jun Kusonoki, Markus R Wenk. Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys?.
PloS one.
2011 May; 6(5):e19731. doi:
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Dermato-endocrinology.
2011 Apr; 3(2):91-9. doi:
10.4161/derm.3.2.14619. [PMID: 21695018] - Agnieszka Broniec, Radoslaw Klosinski, Anna Pawlak, Marta Wrona-Krol, David Thompson, Tadeusz Sarna. Interactions of plasmalogens and their diacyl analogs with singlet oxygen in selected model systems.
Free radical biology & medicine.
2011 Apr; 50(7):892-8. doi:
10.1016/j.freeradbiomed.2011.01.002. [PMID: 21236336] - Fong-Chin Huang, Wilfried Schwab. Cloning and characterization of a 9-lipoxygenase gene induced by pathogen attack from Nicotiana benthamiana for biotechnological application.
BMC biotechnology.
2011 Mar; 11(?):30. doi:
10.1186/1472-6750-11-30. [PMID: 21450085] - Vildes Maria Scussel, Barbara Nantua Giordano, Vanessa Simao, Daniel Manfio, Simone Galvao, Manuel Nazaré Ferreira Rodrigues. Effect of Oxygen-Reducing Atmospheres on the Safety of Packaged Shelled Brazil Nuts during Storage.
International journal of analytical chemistry.
2011; 2011(?):813591. doi:
10.1155/2011/813591. [PMID: 21760791] - Andreas Ullen, Günter Fauler, Harald Köfeler, Sabine Waltl, Christoph Nusshold, Eva Bernhart, Helga Reicher, Hans-Jörg Leis, Andrea Wintersperger, Ernst Malle, Wolfgang Sattler. Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo.
Free radical biology & medicine.
2010 Dec; 49(11):1655-65. doi:
10.1016/j.freeradbiomed.2010.08.025. [PMID: 20807565] - Lijuan Peng, Gary R Kinsel. Characterization of plasma polymerized C, H, and O containing compounds by MALDI mass spectrometry.
Langmuir : the ACS journal of surfaces and colloids.
2010 Nov; 26(22):17477-81. doi:
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Journal of experimental botany.
2010 Jun; 61(10):2589-601. doi:
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Journal of lipid research.
2010 May; 51(5):1085-92. doi:
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Plant physiology and biochemistry : PPB.
2010 Apr; 48(4):225-31. doi:
10.1016/j.plaphy.2010.01.012. [PMID: 20137961] - Masanori Honsho, Shunsuke Asaoku, Yukio Fujiki. Posttranslational regulation of fatty acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis.
The Journal of biological chemistry.
2010 Mar; 285(12):8537-42. doi:
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Langmuir : the ACS journal of surfaces and colloids.
2010 Jan; 26(2):938-42. doi:
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Chemical research in toxicology.
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Biosensors & bioelectronics.
2009 Oct; 25(2):519-22. doi:
10.1016/j.bios.2009.07.033. [PMID: 19700300] - Darren Locke, Andrew L Harris. Connexin channels and phospholipids: association and modulation.
BMC biology.
2009 Aug; 7(?):52. doi:
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Organic letters.
2009 Jul; 11(13):2784-7. doi:
10.1021/ol9009078. [PMID: 19499908] - Michael A Kiebish, Xianlin Han, Hua Cheng, Thomas N Seyfried. In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from non-tumorigenic astrocytes and brain tumours.
ASN neuro.
2009 May; 1(3):. doi:
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Colloids and surfaces. B, Biointerfaces.
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Journal of experimental botany.
2009; 60(4):1231-40. doi:
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Bioconjugate chemistry.
2009 Jan; 20(1):47-59. doi:
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Current medicinal chemistry.
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PloS one.
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Langmuir : the ACS journal of surfaces and colloids.
2008 Dec; 24(24):14296-305. doi:
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Journal of lipid research.
2008 Dec; 49(12):2668-77. doi:
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Biomacromolecules.
2008 Nov; 9(11):3119-26. doi:
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Biochemistry.
2008 Aug; 47(31):8237-45. doi:
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Phytochemistry.
2008 Jul; 69(10):2008-15. doi:
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PloS one.
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Phytochemistry.
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Plant physiology.
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The Journal of biological chemistry.
2003 Sep; 278(38):36365-72. doi:
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