p-Tolualdehyde (BioDeep_00001867714)

Main id: BioDeep_00000006322

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


4-Methylbenzaldehyde

化学式: C8H8O (120.0575)
中文名称: 对甲基苯甲醛, 4-甲基苯甲醛
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC=C(C=C1)C=O
InChI: InChI=1S/C8H8O/c1-7-2-4-8(6-9)5-3-7/h2-6H,1H3

描述信息

A tolualdehyde compound with the methyl substituent at the 4-position.
p-Tolualdehyde is an endogenous metabolite.
p-Tolualdehyde is an endogenous metabolite.

同义名列表

4 个代谢物同义名

p-Tolualdehyde; 4-Methylbenzaldehyde; p-Tolualdehyde; 4-Methylbenzaldehyde



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

43 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 CA1, CA2, CALR, EGFR, ESR1, NFKB1, PPARG, TAP2, TYR
Peripheral membrane protein 1 ESR1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 6 CALR, CANX, EGFR, TAP1, TAP2, TAPBP
Mitochondrion membrane 1 CANX
Nucleus 8 ACR, CALR, EGFR, ESR1, ESR2, NFKB1, PPARG, SERF1A
cytosol 7 CA1, CA2, CALR, ESR1, NFKB1, PPARG, SERF1A
mitochondrial membrane 1 CANX
nucleoplasm 5 ESR1, ESR2, NFKB1, PPARG, SLC3A2
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 6 CA2, EGFR, ESR1, OR12D2, SCN4A, SLC3A2
Cytoplasmic side 1 ESR1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 4 OR12D2, SCN4A, TAP1, TAP2
Synapse 1 SLC3A2
cell junction 2 EGFR, SLC3A2
cell surface 3 CALR, EGFR, SLC3A2
glutamatergic synapse 2 CALR, EGFR
Golgi apparatus 1 ESR1
Golgi membrane 2 EGFR, TAPBP
lysosomal membrane 1 SLC3A2
postsynapse 1 CALR
smooth endoplasmic reticulum 1 CALR
Cytoplasm, cytosol 2 CALR, SERF1A
Lysosome 1 TYR
Presynapse 1 CANX
acrosomal vesicle 1 CALR
endosome 1 EGFR
plasma membrane 7 CA2, EGFR, ESR1, OR12D2, SCN4A, SLC3A2, TAP1
Membrane 11 CALR, CANX, EGFR, ESR1, OR12D2, SCN4A, SERF1A, SLC3A2, TAP1, TAP2, TAPBP
apical plasma membrane 2 EGFR, SLC3A2
basolateral plasma membrane 2 EGFR, SLC3A2
extracellular exosome 6 CA1, CA2, CALR, CANX, SLC3A2, TAP2
Lysosome membrane 1 SLC3A2
endoplasmic reticulum 5 CALR, CANX, TAP1, TAP2, TAPBP
extracellular space 3 CALR, CXCL8, EGFR
perinuclear region of cytoplasm 4 CALR, EGFR, PPARG, TYR
mitochondrion 2 ESR2, NFKB1
protein-containing complex 4 ACR, EGFR, ESR1, SERF1A
intracellular membrane-bounded organelle 3 ESR2, PPARG, TYR
Single-pass type I membrane protein 4 CANX, EGFR, TAPBP, TYR
Secreted 1 CXCL8
extracellular region 4 ACR, CALR, CXCL8, NFKB1
Single-pass membrane protein 1 CANX
anchoring junction 1 SLC3A2
transcription regulator complex 2 ESR1, NFKB1
centriolar satellite 1 TAP1
nuclear membrane 2 CANX, EGFR
external side of plasma membrane 1 CALR
Secreted, extracellular space, extracellular matrix 1 CALR
Melanosome membrane 2 CANX, TYR
apical part of cell 1 CA2
Golgi-associated vesicle 2 ACR, TYR
Single-pass type II membrane protein 1 SLC3A2
Apical cell membrane 1 SLC3A2
Membrane raft 1 EGFR
focal adhesion 2 CALR, EGFR
intracellular vesicle 1 EGFR
collagen-containing extracellular matrix 1 CALR
nuclear speck 1 TAP2
receptor complex 2 EGFR, PPARG
chromatin 4 ESR1, ESR2, NFKB1, PPARG
phagocytic vesicle membrane 4 CALR, TAP1, TAP2, TAPBP
Basolateral cell membrane 1 SLC3A2
nuclear envelope 1 CALR
Endomembrane system 1 TAPBP
mitochondria-associated endoplasmic reticulum membrane contact site 1 CANX
Melanosome 2 SLC3A2, TYR
euchromatin 1 ESR1
myelin sheath 1 CA2
basal plasma membrane 2 EGFR, SLC3A2
synaptic membrane 1 EGFR
secretory granule lumen 1 NFKB1
endoplasmic reticulum quality control compartment 2 CALR, CANX
endoplasmic reticulum lumen 2 CALR, CANX
specific granule lumen 1 NFKB1
Endoplasmic reticulum-Golgi intermediate compartment membrane 4 CALR, TAP1, TAP2, TAPBP
clathrin-coated endocytic vesicle membrane 1 EGFR
Sarcoplasmic reticulum lumen 1 CALR
[Isoform 1]: Nucleus 1 ESR1
lumenal side of endoplasmic reticulum membrane 3 CALR, CANX, TAPBP
MHC class I peptide loading complex 4 CALR, TAP1, TAP2, TAPBP
Tapasin-ERp57 complex 1 TAPBP
voltage-gated sodium channel complex 1 SCN4A
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
endocytic vesicle lumen 1 CALR
ribosome 1 CALR
Cytoplasmic vesicle, secretory vesicle, Cortical granule 1 CALR
cortical granule 1 CALR
amino acid transport complex 1 SLC3A2
apical pole of neuron 1 SLC3A2
acrosomal matrix 1 ACR
Cytolytic granule 1 CALR
[Nuclear factor NF-kappa-B p105 subunit]: Cytoplasm 1 NFKB1
[Nuclear factor NF-kappa-B p50 subunit]: Nucleus 1 NFKB1
I-kappaB/NF-kappaB complex 1 NFKB1
NF-kappaB p50/p65 complex 1 NFKB1
TAP complex 2 TAP1, TAP2


文献列表

  • Simone K Huber, Georg Höfner, Klaus T Wanner. Application of the concept of oxime library screening by mass spectrometry (MS) binding assays to pyrrolidine-3-carboxylic acid derivatives as potential inhibitors of γ-aminobutyric acid transporter 1 (GAT1). Bioorganic & medicinal chemistry. 2019 07; 27(13):2753-2763. doi: 10.1016/j.bmc.2019.05.001. [PMID: 31097402]
  • Lu Song, Dan Gao, Shangfu Li, Yanwei Wang, Hongxia Liu, Yuyang Jiang. Simultaneous quantitation of hydrazine and acetylhydrazine in human plasma by high performance liquid chromatography-tandem mass spectrometry after derivatization with p-tolualdehyde. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Sep; 1063(?):189-195. doi: 10.1016/j.jchromb.2017.08.036. [PMID: 28881295]
  • Jong H Kim, Kathleen L Chan, Noreen Mahoney, Bruce C Campbell. Antifungal activity of redox-active benzaldehydes that target cellular antioxidation. Annals of clinical microbiology and antimicrobials. 2011 May; 10(?):23. doi: 10.1186/1476-0711-10-23. [PMID: 21627838]
  • Juan Huang, Yanli Feng, Jiamo Fu, Guoying Sheng. A method of detecting carbonyl compounds in tree leaves in China. Environmental science and pollution research international. 2010 Jun; 17(5):1129-36. doi: 10.1007/s11356-009-0277-3. [PMID: 20016999]
  • Francesca Cutillo, Marina DellaGreca, Melania Gionti, Lucio Previtera, Armando Zarrelli. Phenols and lignans from Chenopodium album. Phytochemical analysis : PCA. 2006 Sep; 17(5):344-9. doi: 10.1002/pca.924. [PMID: 17019936]