Pomiferin (BioDeep_00000017366)

Main id: BioDeep_00000270639

Secondary id: BioDeep_00000003784

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


4H,8H-BENZO(1,2-B:3,4-B)DIPYRAN-4-ONE, 3-(3,4-DIHYDROXYPHENYL)-5-HYDROXY-8,8-DIMETHYL-6-(3-METHYL-2-BUTEN-1-YL)-

化学式: C25H24O6 (420.1572804)
中文名称: 橙桑黄酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12OC(C)(C)C=CC=1C1OC=C(C3=CC=C(O)C(O)=C3)C(=O)C=1C(O)=C2C/C=C(/C)\C
InChI: InChI=1S/C25H24O6/c1-13(2)5-7-15-21(28)20-22(29)17(14-6-8-18(26)19(27)11-14)12-30-24(20)16-9-10-25(3,4)31-23(15)16/h5-6,8-12,26-28H,7H2,1-4H3

描述信息

Pomiferin is a member of isoflavanones.
Pomiferin is a natural product found in Derris montana, Maclura pomifera, and other organisms with data available.

同义名列表

27 个代谢物同义名

4H,8H-BENZO(1,2-B:3,4-B)DIPYRAN-4-ONE, 3-(3,4-DIHYDROXYPHENYL)-5-HYDROXY-8,8-DIMETHYL-6-(3-METHYL-2-BUTEN-1-YL)-; 4H,8H-Benzo(1,2-b:3,4-b)dipyran-4-one, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-; 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methylbut-2-enyl)-4H,8H- pyrano[2,3-h]chromen-4-one; 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-pyrano[2,3-f]chromen-4-one; 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methylbut-2-enyl)-4H,8H-pyrano(2,3-h)chromen-4-one; 4H,2-b:3,4-b]dipyran-4-one, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-; 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one; Spectrum5_000515; NCIStruc2_001049; Spectrum4_001808; NCIStruc1_001168; Spectrum3_000685; Spectrum2_000799; POMIFERIN [INCI]; 3-HYDROXYOSAJIN; UNII-74YIS40APM; DivK1c_000996; KBio2_000775; KBio1_000996; KBio2_003343; KBio2_005911; KBio3_001629; NCI60_004233; IDI1_000996; 74YIS40APM; Pomiferin; AI3-22130



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Esra Dilek, Hüseyin Serkan Erol, Ahmet Cakir, Murat Koc, Mesut Bünyami Halici. Natural product inhibitors of carbonic anhydrase I and II isoenzymes: osajin and pomiferin. Archives of physiology and biochemistry. 2017 Oct; 123(4):219-224. doi: 10.1080/13813455.2017.1303742. [PMID: 28338341]
  • Giovanni Ribaudo, Mario Angelo Pagano, Valeria Pavan, Marco Redaelli, Maira Zorzan, Raffaele Pezzani, Carla Mucignat-Caretta, Tiziano Vendrame, Sergio Bova, Giuseppe Zagotto. Semi-synthetic derivatives of natural isoflavones from Maclura pomifera as a novel class of PDE-5A inhibitors. Fitoterapia. 2015 Sep; 105(?):132-8. doi: 10.1016/j.fitote.2015.06.020. [PMID: 26136059]
  • Hyung-In Moon. Effect of osajin and pomiferin on antidiabetic effects from normal and streptozotocin-induced diabetic rats. Natural product communications. 2014 Dec; 9(12):1723-4. doi: . [PMID: 25632468]
  • Tsung-Teng Huang, Fu-Guo Liu, Chia-Fong Wei, Chia-Chen Lu, Chang-Chieh Chen, Hung-Chi Lin, David M Ojcius, Hsin-Chih Lai. Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin. PloS one. 2011 Apr; 6(4):e18308. doi: 10.1371/journal.pone.0018308. [PMID: 21532751]
  • Lenka Bartošíková, Jiří Nečas, Tomáš Bartošík, Martin Pavlík, Petr Fráňa. Effect of pomiferin administration on kidney ischaemia-reperfusion injury in rats. Interdisciplinary toxicology. 2010 Jun; 3(2):76-81. doi: 10.2478/v10102-010-0015-1. [PMID: 21217877]
  • James V Gruber, Robert Holtz. Examining the genomic influence of skin antioxidants in vitro. Mediators of inflammation. 2010; 2010(?):. doi: 10.1155/2010/230450. [PMID: 20706672]
  • I Orhan, F S Senol, M Kartal, M Dvorská, M Zemlicka, K Smejkal, P Mokrý. Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2009 Aug; 47(8):1747-51. doi: 10.1016/j.fct.2009.04.023. [PMID: 19394400]
  • Vaclav Diopan, Petr Babula, Violetta Shestivska, Vojtech Adam, Milan Zemlicka, Margita Dvorska, Jaromir Hubalek, Libuse Trnkova, Ladislav Havel, Rene Kizek. Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide. Journal of pharmaceutical and biomedical analysis. 2008 Sep; 48(1):127-33. doi: 10.1016/j.jpba.2008.05.025. [PMID: 18597965]
  • Il Hong Son, Ill-Min Chung, Sung Ik Lee, Hyun Duk Yang, Hyung-In Moon. Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera. Bioorganic & medicinal chemistry letters. 2007 Sep; 17(17):4753-5. doi: 10.1016/j.bmcl.2007.06.060. [PMID: 17662606]
  • L Bartosíková, J Necas, T Bartosík, M Pavlík, J Fránová, G Kuzmina, J Luza. [Examination of the antioxidative and antidiabetic effect of pomiferin in alloxan-induced diabetes mellitus in an experiment (a pilot study)]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 2007 Jun; 56(3):135-40. doi: . [PMID: 17867526]
  • J Necas, L Bartosíková, T Florian, J Klusáková, V Suchý, E M B Naggar, E Janostíková, T Bartosík, M Lisková. [Protective effects of the flavonoids osajin and pomiferin on heart ischemia-reperfusion]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 2006 Jul; 55(4):168-74. doi: . [PMID: 16921735]
  • Tomas Florian, Jiri Necas, Lenka Bartosikova, Jarmila Klusakova, Vaclav Suchy, Elmoataz B El Naggara, Eva Janostikova, Tomas Bartosik. Effects of prenylated isoflavones osajin and pomiferin in premedication on heart ischemia-reperfusion. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 2006 Jul; 150(1):93-100. doi: 10.5507/bp.2006.013. [PMID: 16936909]
  • Dagmar Veselá, Renáta Kubínová, Jan Muselík, Milan Zemlicka, Václav Suchý. Antioxidative and EROD activities of osajin and pomiferin. Fitoterapia. 2004 Mar; 75(2):209-11. doi: 10.1016/j.fitote.2003.12.005. [PMID: 15030927]
  • Rong Tsao, Raymond Yang, J Christopher Young. Antioxidant isoflavones in Osage orange, Maclura pomifera (Raf.) Schneid. Journal of agricultural and food chemistry. 2003 Oct; 51(22):6445-51. doi: 10.1021/jf0342369. [PMID: 14558760]