Erythritol (BioDeep_00000001731)

 

Secondary id: BioDeep_00000408246

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


1,2,3,4-Butanetetrol,(2R,3R)-rel-

化学式: C4H10O4 (122.0579)
中文名称: 赤藓糖醇, DL-苏糖醇
谱图信息: 最多检出来源 Homo sapiens(feces) 26.4%

Reviewed

Last reviewed on 2024-07-16.

Cite this Page

Erythritol. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/erythritol (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000001731). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C(C(CO)O)O)O
InChI: InChI=1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2

描述信息

Erythritol is a sugar alcohol (or polyol), used as a food additive and sugar substitute. It is naturally occurring and is made from corn using enzymes and fermentation. Its formula is C4H10O4, or HO(CH2)(CHOH)2(CH2)OH; specifically, one particular stereoisomer with that formula. Erythritol is 60–70\\\\\% as sweet as sucrose (table sugar), yet it is almost noncaloric and does not affect blood sugar or cause tooth decay. Erythritol occurs widely in nature and has been found to occur naturally in several foods including wine, sake, beer, watermelon, pear, grape, and soy sauce. Evidence indicates that erythritol also exists endogenously in the tissues and body fluids of humans and animals. Erythritol is absorbed from the proximal intestine by passive diffusion in a manner similar to that of many low molecular weight organic molecules which do not have associated active transport systems. The rate of absorption is related to their molecular size. It passes through the intestinal membranes at a faster rate than larger molecules such as mannitol or glucose. In diabetics, erythritol has also been shown to be rapidly absorbed and excreted unchanged in the urine. Following absorption, ingested erythritol is rapidly distributed throughout the body and has been reported to occur in hepatocytes, pancreatic cells, and vascular smooth muscle cells. Erythritol also has been reported to cross the human placenta and to pass slowly from the plasma into the brain and cerebrospinal fluid (PMID:9862657). Erythritol is found to be associated with ribose-5-phosphate isomerase deficiency, which is an inborn error of metabolism.
Bulk sweetener with good taste props. Not metabolised, excreted unchanged in urine. Less sweet than sucrose. Use not yet permitted in most countries (1997). GRAS status for use as a sweetener, thickener, stabiliser, humectant, etc. in food
meso-Erythritol is a sugar alcohol that occurs naturally in a variety of foods (e.g., pear, watermelon), is 60-80\\% as sweet as sucrose, and is an approved low-calorie sweetener food additive[1].
meso-Erythritol is a sugar alcohol that occurs naturally in a variety of foods (e.g., pear, watermelon), is 60-80\% as sweet as sucrose, and is an approved low-calorie sweetener food additive[1].

同义名列表

30 个代谢物同义名

1,2,3,4-Butanetetrol,(2R,3R)-rel-; (2S,3R)-butane-1,2,3,4-tetrol; (2R,3S)-Butane-1,2,3,4-tetrol; 1,2,3,4-Tetrahydroxybutane; Butane-1,2,3,4-tetrol; 1,2,3,4-Butanetetrol; Tetrahydroxybutane; Erythro-tetritol; MESO-erythritol; Mesoerythritol; L-(-)-Threitol; Meso-eythritol; Erythroglucin; Antierythrite; L-Erythritol; Lichen sugar; Butanetetrol; I-erythritol; Erythritol; L-Threitol; Erythrite; Phycitol; Erythrit; Erythrol; C*Eridex; Paycite; Phycite; Erythritol; Erythritol; Erythritol



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

34 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AKR1B1, ALB, CAT, G6PD, GK, SHPK
Peripheral membrane protein 4 G6PD, GBA1, HSD17B6, SORD
Endoplasmic reticulum membrane 1 TKT
Mitochondrion membrane 1 SORD
Nucleus 3 ALB, GK, TAL1
cytosol 9 AKR1B1, ALB, CAT, G6PD, GK, LIPE, SHPK, SORD, TKT
mitochondrial membrane 1 SORD
nuclear body 1 TKT
trans-Golgi network 1 GBA1
centrosome 1 ALB
nucleoplasm 3 AKR1B1, TAL1, TKT
Cell membrane 3 LIPE, TKT, TNF
Early endosome membrane 1 HSD17B6
cell surface 1 TNF
glutamatergic synapse 1 GHRL
Golgi apparatus 2 ALB, GBA1
Golgi membrane 1 INS
lysosomal membrane 2 GAA, GBA1
neuronal cell body 1 TNF
postsynapse 1 GHRL
Cytoplasm, cytosol 3 G6PD, GK, LIPE
Lysosome 2 GAA, GBA1
plasma membrane 4 GAA, GCG, TKT, TNF
Membrane 5 CAT, G6PD, GAA, LIPE, SORD
apical plasma membrane 1 TKT
axon 2 CCK, GHRL
caveola 1 LIPE
extracellular exosome 9 AKR1B1, ALB, CAT, G6PD, GAA, GBA1, GK, SORD, TKT
Lysosome membrane 2 GAA, GBA1
Lumenal side 2 GBA1, HSD17B6
endoplasmic reticulum 3 ALB, GBA1, HSD17B6
extracellular space 10 AKR1B1, ALB, CCK, GCG, GHRL, INS, PYY, SCT, SORD, TNF
lysosomal lumen 2 GAA, GBA1
Schaffer collateral - CA1 synapse 1 GHRL
mitochondrion 3 AKR1B1, CAT, GK
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 4 CAT, G6PD, GAA, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 1 TKT
Secreted 6 ALB, CCK, GAA, GCG, GHRL, INS
extracellular region 10 ALB, CAT, CCK, GAA, GCG, GHRL, INS, PYY, SCT, TNF
cytoplasmic side of plasma membrane 1 G6PD
Mitochondrion outer membrane 1 GK
Single-pass membrane protein 1 GK
mitochondrial outer membrane 1 GK
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
transcription regulator complex 1 TAL1
centriolar satellite 1 G6PD
motile cilium 1 SORD
external side of plasma membrane 1 TNF
actin cytoskeleton 1 TKT
neuronal dense core vesicle lumen 1 GHRL
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 TKT
Membrane raft 1 TNF
focal adhesion 2 CAT, TKT
Peroxisome 2 CAT, TKT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
receptor complex 1 TKT
ciliary basal body 1 ALB
chromatin 1 TAL1
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Cell projection, cilium, flagellum 1 SORD
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
tertiary granule membrane 1 GAA
[Isoform 4]: Cytoplasm, cytosol 1 GK
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 4 CAT, GCG, GHRL, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, GCG, GHRL, INS
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
ficolin-1-rich granule membrane 1 GAA
[Glucagon-like peptide 1]: Secreted 1 GCG
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
autolysosome lumen 1 GAA
[Isoform 3]: Mitochondrion outer membrane 1 GK
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Fangmei Liu, Kai Xia, Yuqing Chen, Ling Zhu, Lingzhi Zhu, Xuequn Zhao, Ruyi Sha, Jun Huang. Inhibition of hyphal formation together with biochar addition promotes erythritol production by Yarrowia lipolytica. Biotechnology and bioengineering. 2024 Jun; 121(6):1937-1949. doi: 10.1002/bit.28704. [PMID: 38548668]
  • Diego González-Cabanelas, Erica Perreca, Johann M Rohwer, Axel Schmidt, Tobias Engl, Bettina Raguschke, Jonathan Gershenzon, Louwrance P Wright. Deoxyxylulose 5-Phosphate Synthase Does Not Play a Major Role in Regulating the Methylerythritol 4-Phosphate Pathway in Poplar. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084181. [PMID: 38673766]
  • Ewa Raczkowska, Aneta Wojdyło, Paulina Nowicka. The use of blackcurrant pomace and erythritol to optimise the functional properties of shortbread cookies. Scientific reports. 2024 02; 14(1):3788. doi: 10.1038/s41598-024-54461-7. [PMID: 38361029]
  • Kai Xia, Fang-Mei Liu, Yu-Qing Chen, Shan-Shan Chen, Chun-Ying Huang, Xue-Qun Zhao, Ru-Yi Sha, Jun Huang. Mechanism and evolutionary analysis of Yarrowia lipolytica CA20 capable of producing erythritol with a high yield based on comparative genomics. Yi chuan = Hereditas. 2023 Oct; 45(10):904-921. doi: 10.16288/j.yczz.23-139. [PMID: 37872113]
  • Xin Wu, Mengwei Bu, Zili Yang, Hongrui Ping, Chunlin Song, Jiang Duan, Aidong Zhang. Design and Synthesis of Fosmidomycin Analogs containing aza-Linkers and Their Biological Activity Evaluation. Pest management science. 2023 Oct; ?(?):. doi: 10.1002/ps.7810. [PMID: 37794283]
  • Anil B Khatape, Vidhya Rangaswamy, Syed G Dastager. Strain improvement for enhanced erythritol production by Moniliella pollinis Mutant-58 using jaggery as a cost-effective substrate. International microbiology : the official journal of the Spanish Society for Microbiology. 2023 Jul; ?(?):. doi: 10.1007/s10123-023-00411-8. [PMID: 37525085]
  • Fan Jiang, Dongying Liu, Jingqi Dai, Tao Yang, Jinzhu Zhang, Daidi Che, Jinping Fan. Cloning and Functional Characterization of 2-C-methyl-D-erythritol-4-phosphate cytidylyltransferase (LiMCT) Gene in Oriental Lily (Lilium 'Sorbonne'). Molecular biotechnology. 2023 Apr; ?(?):. doi: 10.1007/s12033-023-00729-8. [PMID: 37014586]
  • Yueyang Wang, Yue Li, Huiyun Song, Zhi Wang, Pei Li. Characterization of the 1-Deoxy-D-xylulose 5-Phosphate synthase Genes in Toona ciliata Suggests Their Role in Insect Defense. International journal of molecular sciences. 2023 Jan; 24(3):. doi: 10.3390/ijms24032339. [PMID: 36768662]
  • Lea Vidal, Esteban Lebrun, Young-Kyoung Park, Guillaume Mottet, Jean-Marc Nicaud. Bidirectional hybrid erythritol-inducible promoter for synthetic biology in Yarrowia lipolytica. Microbial cell factories. 2023 Jan; 22(1):7. doi: 10.1186/s12934-023-02020-6. [PMID: 36635727]
  • Takanori Kondo, Chihiro Yasui, Ikkei Miyajima, Taisuke Banno, Kouichi Asakura, Tokuma Fukuoka, Kazunori Ushimaru, Maito Koga, Azusa Saika, Tomotake Morita, Yoshiaki Takahashi, Chigusa Hayashi, Masayuki Igarashi, Daisuke Takahashi, Kazunobu Toshima. Synthesis of Mannosylerythritol Lipid Analogues and their Self-Assembling Properties, Recovery Effects on Damaged Skin Cells, and Antibacterial Activity. Chemistry (Weinheim an der Bergstrasse, Germany). 2022 Oct; 28(55):e202201733. doi: 10.1002/chem.202201733. [PMID: 35761481]
  • Ying-Ping Huang, I-Hsuan Chen, Yu-Shun Kao, Yau-Heiu Hsu, Ching-Hsiu Tsai. The gibberellic acid derived from the plastidial MEP pathway is involved in the accumulation of Bamboo mosaic virus. The New phytologist. 2022 08; 235(4):1543-1557. doi: 10.1111/nph.18210. [PMID: 35524450]
  • Yong Yuan, Siyan Ren, Xiaofeng Liu, Liyang Su, Yu Wu, Wen Zhang, Yan Li, Yidan Jiang, Hsihua Wang, Rao Fu, Mondher Bouzayen, Mingchun Liu, Yang Zhang. SlWRKY35 positively regulates carotenoid biosynthesis by activating the MEP pathway in tomato fruit. The New phytologist. 2022 04; 234(1):164-178. doi: 10.1111/nph.17977. [PMID: 35048386]
  • Briana E Price, June-Sun Yoon, Man-Yeon Choi, Jana C Lee. Effects of nonnutritional sugars on lipid and carbohydrate content, physiological uptake, and excretion in Drosophila suzukii. Archives of insect biochemistry and physiology. 2022 Feb; 109(2):e21860. doi: 10.1002/arch.21860. [PMID: 34865250]
  • Meiyu Jin, Yunfei Wei, Hao Yu, Xin Ma, Siru Yan, Lilei Zhao, Lu Ding, Jiaqi Cheng, Haihua Feng. Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity. Journal of agricultural and food chemistry. 2021 Nov; 69(44):13080-13092. doi: 10.1021/acs.jafc.1c05213. [PMID: 34719928]
  • Ülo Niinemets, Bahtijor Rasulov, Eero Talts. CO2 -responsiveness of leaf isoprene emission: Why do species differ?. Plant, cell & environment. 2021 09; 44(9):3049-3063. doi: 10.1111/pce.14131. [PMID: 34155641]
  • Semira R Ortiz, Martha S Field. Chronic Dietary Erythritol Exposure Elevates Plasma Erythritol Concentration in Mice but Does Not Cause Weight Gain or Modify Glucose Homeostasis. The Journal of nutrition. 2021 08; 151(8):2114-2124. doi: 10.1093/jn/nxab130. [PMID: 34091676]
  • Bin Liu, Lu Zhang, Linda Rusalepp, Eve Kaurilind, Hassan Yusuf Sulaiman, Tõnu Püssa, Ülo Niinemets. Heat priming improved heat tolerance of photosynthesis, enhanced terpenoid and benzenoid emission and phenolics accumulation in Achillea millefolium. Plant, cell & environment. 2021 07; 44(7):2365-2385. doi: 10.1111/pce.13830. [PMID: 32583881]
  • Laura Daza-Serna, Sebastián Serna-Loaiza, Audrey Masi, Robert Ludwig Mach, Astrid Rosa Mach-Aigner, Anton Friedl. From the culture broth to the erythritol crystals: an opportunity for circular economy. Applied microbiology and biotechnology. 2021 Jun; 105(11):4467-4486. doi: 10.1007/s00253-021-11355-2. [PMID: 34043080]
  • Bettina K Wölnerhanssen, Jürgen Drewe, Wout Verbeure, Carel W le Roux, Ludmilla Dellatorre-Teixeira, Jens F Rehfeld, Jens J Holst, Bolette Hartmann, Jan Tack, Ralph Peterli, Christoph Beglinger, Anne C Meyer-Gerspach. Gastric emptying of solutions containing the natural sweetener erythritol and effects on gut hormone secretion in humans: A pilot dose-ranging study. Diabetes, obesity & metabolism. 2021 06; 23(6):1311-1321. doi: 10.1111/dom.14342. [PMID: 33565706]
  • Rena Kawano, Takuro Okamura, Yoshitaka Hashimoto, Saori Majima, Takafumi Senmaru, Emi Ushigome, Mai Asano, Masahiro Yamazaki, Hiroshi Takakuwa, Ryoichi Sasano, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui. Erythritol Ameliorates Small Intestinal Inflammation Induced by High-Fat Diets and Improves Glucose Tolerance. International journal of molecular sciences. 2021 May; 22(11):. doi: 10.3390/ijms22115558. [PMID: 34074061]
  • Liping Zeng, Katayoon Dehesh. The eukaryotic MEP-pathway genes are evolutionarily conserved and originated from Chlaymidia and cyanobacteria. BMC genomics. 2021 Feb; 22(1):137. doi: 10.1186/s12864-021-07448-x. [PMID: 33637041]
  • Wu Wang, Jiao Feng, Lingling Wei, Muhammad Khalil-Ur-Rehman, Niels J Nieuwenhuizen, Lina Yang, Huan Zheng, Jianmin Tao. Transcriptomics Integrated with Free and Bound Terpenoid Aroma Profiling during 'Shine Muscat' (Vitis labrusca × V. vinifera) Grape Berry Development Reveals Coordinate Regulation of MEP Pathway and Terpene Synthase Gene Expression. Journal of agricultural and food chemistry. 2021 Feb; 69(4):1413-1429. doi: 10.1021/acs.jafc.0c06591. [PMID: 33481572]
  • Kuo Xu, Xu-Lun Wei, Lin Xue, Zhong-Feng Zhang, Peng Zhang. Antimicrobial Meroterpenoids and Erythritol Derivatives Isolated from the Marine-Algal-Derived Endophytic Fungus Penicillium chrysogenum XNM-12. Marine drugs. 2020 Nov; 18(11):. doi: 10.3390/md18110578. [PMID: 33233849]
  • Karley K Mahalak, Jenni Firrman, Peggy M Tomasula, Alberto Nuñez, Jung-Jin Lee, Kyle Bittinger, William Rinaldi, Lin Shu Liu. Impact of Steviol Glycosides and Erythritol on the Human and Cebus apella Gut Microbiome. Journal of agricultural and food chemistry. 2020 Nov; 68(46):13093-13101. doi: 10.1021/acs.jafc.9b06181. [PMID: 31869223]
  • Semira R Ortiz, Martha S Field. Mammalian metabolism of erythritol: a predictive biomarker of metabolic dysfunction. Current opinion in clinical nutrition and metabolic care. 2020 09; 23(5):296-301. doi: 10.1097/mco.0000000000000665. [PMID: 32412980]
  • Rui Xiong, Zhu Chen, Weiyu Wang, Li Jiang, Yan Xiang, Jun Fan. Combined transcriptome sequencing and prokaryotic expression to investigate the key enzyme in the 2-C-methylerythritol-4-phosphate pathway of Osmanthus fragrans. Functional plant biology : FPB. 2020 09; 47(10):945-958. doi: 10.1071/fp19365. [PMID: 32527366]
  • Xueliang Qiu, Peng Xu, Xinrui Zhao, Guocheng Du, Juan Zhang, Jianghua Li. Combining genetically-encoded biosensors with high throughput strain screening to maximize erythritol production in Yarrowia lipolytica. Metabolic engineering. 2020 07; 60(?):66-76. doi: 10.1016/j.ymben.2020.03.006. [PMID: 32224262]
  • Naoto Katakami, Kazuo Omori, Naohiro Taya, Shoya Arakawa, Mitsuyoshi Takahara, Taka-Aki Matsuoka, Hiroshi Tsugawa, Masahiro Furuno, Takeshi Bamba, Eiichiro Fukusaki, Iichiro Shimomura. Plasma metabolites associated with arterial stiffness in patients with type 2 diabetes. Cardiovascular diabetology. 2020 06; 19(1):75. doi: 10.1186/s12933-020-01057-w. [PMID: 32527273]
  • Yifeng Zhang, Yujun Zhao, Jiadian Wang, Tianyuan Hu, Yuru Tong, Jiawei Zhou, Jie Gao, Luqi Huang, Wei Gao. The expression of TwDXS in the MEP pathway specifically affects the accumulation of triptolide. Physiologia plantarum. 2020 May; 169(1):40-48. doi: 10.1111/ppl.13051. [PMID: 31758560]
  • M K You, Y J Lee, J K Kim, S A Baek, Y A Jeon, S H Lim, S H Ha. The organ-specific differential roles of rice DXS and DXR, the first two enzymes of the MEP pathway, in carotenoid metabolism in Oryza sativa leaves and seeds. BMC plant biology. 2020 Apr; 20(1):167. doi: 10.1186/s12870-020-02357-9. [PMID: 32293285]
  • Arvind Sharma, Jeremiah Reyes, David Borgmeyer, Cuauhtemoc Ayala-Chavez, Katie Snow, Fiza Arshad, Andrew Nuss, Monika Gulia-Nuss. The sugar substitute erythritol shortens the lifespan of Aedes aegypti potentially by N-linked protein glycosylation. Scientific reports. 2020 04; 10(1):6195. doi: 10.1038/s41598-020-63050-3. [PMID: 32277123]
  • Jili Wang, Yaqing Zhou, Xiuwen Wang, Lixia Duan, Jiang Duan, Weiguo Li, Aidong Zhang. Synthesis and Evaluation of Halogenated 5-(2-Hydroxyphenyl)pyrazoles as Pseudilin Analogues Targeting the Enzyme IspD in the Methylerythritol Phosphate Pathway. Journal of agricultural and food chemistry. 2020 Mar; 68(10):3071-3078. doi: 10.1021/acs.jafc.9b08057. [PMID: 32078770]
  • Jin-Zheng Wang, Yongxing Lei, Yanmei Xiao, Xiang He, Jiubo Liang, Jishan Jiang, Shangzhi Dong, Haiyan Ke, Patricia Leon, Philipp Zerbe, Youli Xiao, Katayoon Dehesh. Uncovering the functional residues of Arabidopsis isoprenoid biosynthesis enzyme HDS. Proceedings of the National Academy of Sciences of the United States of America. 2020 01; 117(1):355-361. doi: 10.1073/pnas.1916434117. [PMID: 31879352]
  • Enrico Orsi, Jules Beekwilder, Siebe Peek, Gerrit Eggink, Servé W M Kengen, Ruud A Weusthuis. Metabolic flux ratio analysis by parallel 13C labeling of isoprenoid biosynthesis in Rhodobacter sphaeroides. Metabolic engineering. 2020 01; 57(?):228-238. doi: 10.1016/j.ymben.2019.12.004. [PMID: 31843486]
  • Matthew E Bergman, Benjamin Davis, Michael A Phillips. Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action. Molecules (Basel, Switzerland). 2019 Nov; 24(21):. doi: 10.3390/molecules24213961. [PMID: 31683764]
  • Lisa Schlicker, Doletha M E Szebenyi, Semira R Ortiz, Alexander Heinz, Karsten Hiller, Martha S Field. Unexpected roles for ADH1 and SORD in catalyzing the final step of erythritol biosynthesis. The Journal of biological chemistry. 2019 11; 294(44):16095-16108. doi: 10.1074/jbc.ra119.009049. [PMID: 31511322]
  • Garima Ayachit, Inayatullah Shaikh, Preeti Sharma, Bhavika Jani, Labdhi Shukla, Priyanka Sharma, Shivarudrappa B Bhairappanavar, Chaitanya Joshi, Jayashankar Das. De novo transcriptome of Gymnema sylvestre identified putative lncRNA and genes regulating terpenoid biosynthesis pathway. Scientific reports. 2019 10; 9(1):14876. doi: 10.1038/s41598-019-51355-x. [PMID: 31619732]
  • Jishan Jiang, Liping Zeng, Haiyan Ke, Brittenny De La Cruz, Katayoon Dehesh. Orthogonal regulation of phytochrome B abundance by stress-specific plastidial retrograde signaling metabolite. Nature communications. 2019 07; 10(1):2904. doi: 10.1038/s41467-019-10867-w. [PMID: 31266952]
  • Nawaporn Onkokesung, Michael Reichelt, Louwrance P Wright, Michael A Phillips, Jonathan Gershenzon, Marcel Dicke. The plastidial metabolite 2-C-methyl-D-erythritol-2,4-cyclodiphosphate modulates defence responses against aphids. Plant, cell & environment. 2019 07; 42(7):2309-2323. doi: 10.1111/pce.13538. [PMID: 30786032]
  • Le Xue, Zilong He, Xiaochun Bi, Wei Xu, Ting Wei, Shuangxiu Wu, Songnian Hu. Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng. BMC genomics. 2019 May; 20(1):383. doi: 10.1186/s12864-019-5718-x. [PMID: 31101014]
  • Lili Zhang, Xuan Zhang, Xiaoji Wang, Jing Xu, Min Wang, Lin Li, Guanghong Bai, Hui Fang, Shuting Hu, Jigang Li, Jianbing Yan, Jiansheng Li, Xiaohong Yang. SEED CAROTENOID DEFICIENT Functions in Isoprenoid Biosynthesis via the Plastid MEP Pathway. Plant physiology. 2019 04; 179(4):1723-1738. doi: 10.1104/pp.18.01148. [PMID: 30718347]
  • Matthew A Jones. Retrograde signalling as an informant of circadian timing. The New phytologist. 2019 03; 221(4):1749-1753. doi: 10.1111/nph.15525. [PMID: 30299544]
  • Thiagarayaselvam Aarthy, Fayaj A Mulani, Avinash Pandreka, Ashish Kumar, Sharvani S Nandikol, Saikat Haldar, Hirekodathakallu V Thulasiram. Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension. BMC plant biology. 2018 Oct; 18(1):230. doi: 10.1186/s12870-018-1447-6. [PMID: 30314459]
  • Chika Ifeanyi Chukwuma, Ramgopal Mopuri, Savania Nagiah, Anil Amichund Chuturgoon, Md Shahidul Islam. Erythritol reduces small intestinal glucose absorption, increases muscle glucose uptake, improves glucose metabolic enzymes activities and increases expression of Glut-4 and IRS-1 in type 2 diabetic rats. European journal of nutrition. 2018 Oct; 57(7):2431-2444. doi: 10.1007/s00394-017-1516-x. [PMID: 28770335]
  • Julia Emiliani, Lucio D'Andrea, María Lorena Falcone Ferreyra, Evangelina Maulión, Eduardo Rodriguez, Manuel Rodriguez-Concepción, Paula Casati. A role for β,β-xanthophylls in Arabidopsis UV-B photoprotection. Journal of experimental botany. 2018 09; 69(20):4921-4933. doi: 10.1093/jxb/ery242. [PMID: 29945243]
  • Hidenobu Uchida, Koremitsu Sumimoto, Tomoka Oki, Ichiro Nishii, Eiichi Mizohata, Shigeki Matsunaga, Shigeru Okada. Isolation and characterization of 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene from Botryococcus braunii, race B. Journal of plant research. 2018 Sep; 131(5):839-848. doi: 10.1007/s10265-018-1039-4. [PMID: 29725892]
  • Mariaevelina Alfieri, Maria Carmela Vaccaro, Elisa Cappetta, Alfredo Ambrosone, Nunziatina De Tommasi, Antonietta Leone. Coactivation of MEP-biosynthetic genes and accumulation of abietane diterpenes in Salvia sclarea by heterologous expression of WRKY and MYC2 transcription factors. Scientific reports. 2018 07; 8(1):11009. doi: 10.1038/s41598-018-29389-4. [PMID: 30030474]
  • Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
  • Jishan Jiang, Cecilia Rodriguez-Furlan, Jin-Zheng Wang, Amancio de Souza, Haiyan Ke, Taras Pasternak, Hanna Lasok, Franck A Ditengou, Klaus Palme, Katayoon Dehesh. Interplay of the two ancient metabolites auxin and MEcPP regulates adaptive growth. Nature communications. 2018 06; 9(1):2262. doi: 10.1038/s41467-018-04708-5. [PMID: 29891932]
  • Casey M Rebholz, Bing Yu, Zihe Zheng, Patrick Chang, Adrienne Tin, Anna Köttgen, Lynne E Wagenknecht, Josef Coresh, Eric Boerwinkle, Elizabeth Selvin. Serum metabolomic profile of incident diabetes. Diabetologia. 2018 05; 61(5):1046-1054. doi: 10.1007/s00125-018-4573-7. [PMID: 29556673]
  • Nico Betterle, Anastasios Melis. Heterologous Leader Sequences in Fusion Constructs Enhance Expression of Geranyl Diphosphate Synthase and Yield of β-Phellandrene Production in Cyanobacteria ( Synechocystis). ACS synthetic biology. 2018 03; 7(3):912-921. doi: 10.1021/acssynbio.7b00431. [PMID: 29397685]
  • Aditya Vikram Agarwal, Deeksha Singh, Yogeshwar Vikram Dhar, Rahul Michael, Parul Gupta, Deepak Chandra, Prabodh Kumar Trivedi. Virus-Induced Silencing of Key Genes Leads to Differential Impact on Withanolide Biosynthesis in the Medicinal Plant, Withania somnifera. Plant & cell physiology. 2018 Feb; 59(2):262-274. doi: 10.1093/pcp/pcx179. [PMID: 29165715]
  • P de Cock. Erythritol Functional Roles in Oral-Systemic Health. Advances in dental research. 2018 02; 29(1):104-109. doi: 10.1177/0022034517736499. [PMID: 29355425]
  • Justin P Hawkins, Patricia A Ordonez, Ivan J Oresnik. Characterization of Mutations That Affect the Nonoxidative Pentose Phosphate Pathway in Sinorhizobium meliloti. Journal of bacteriology. 2018 01; 200(2):. doi: 10.1128/jb.00436-17. [PMID: 29084855]
  • Sara E Scanga, Bilal Hasanspahič, Edin Zvorničanin, Jasmina Samardžić Koženjić, Andrew K Rahme, Jessica H Shinn-Thomas. Erythritol, at insecticidal doses, has harmful effects on two common agricultural crop plants. PloS one. 2018; 13(4):e0192749. doi: 10.1371/journal.pone.0192749. [PMID: 29664905]
  • Rui Huang, Yang Wang, Pingrong Wang, Chunmei Li, Fuliang Xiao, Nenggang Chen, Na Li, Caixia Li, Changhui Sun, Lihua Li, Rongjun Chen, Zhengjun Xu, Jianqing Zhu, Xiaojian Deng. A single nucleotide mutation of IspF gene involved in the MEP pathway for isoprenoid biosynthesis causes yellow-green leaf phenotype in rice. Plant molecular biology. 2018 Jan; 96(1-2):5-16. doi: 10.1007/s11103-017-0668-7. [PMID: 29143298]
  • Masaaki Konishi, Motoki Makino. Selective production of deacetylated mannosylerythritol lipid, MEL-D, by acetyltransferase disruption mutant of Pseudozyma hubeiensis. Journal of bioscience and bioengineering. 2018 Jan; 125(1):105-110. doi: 10.1016/j.jbiosc.2017.08.003. [PMID: 28847576]
  • Michael L Fisher, Fallon E Fowler, Steven S Denning, David W Watson. Survival of the House Fly (Diptera: Muscidae) on Truvia and Other Sweeteners. Journal of medical entomology. 2017 07; 54(4):999-1005. doi: 10.1093/jme/tjw241. [PMID: 28399265]
  • Adam Jozwiak, Agata Lipko, Magdalena Kania, Witold Danikiewicz, Liliana Surmacz, Agnieszka Witek, Jacek Wojcik, Konrad Zdanowski, Cezary Pączkowski, Tadeusz Chojnacki, Jaroslaw Poznanski, Ewa Swiezewska. Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis. Plant physiology. 2017 Jun; 174(2):857-874. doi: 10.1104/pp.17.00036. [PMID: 28385729]
  • Katie C Hootman, Jean-Pierre Trezzi, Lisa Kraemer, Lindsay S Burwell, Xiangyi Dong, Kristin A Guertin, Christian Jaeger, Patrick J Stover, Karsten Hiller, Patricia A Cassano. Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults. Proceedings of the National Academy of Sciences of the United States of America. 2017 05; 114(21):E4233-E4240. doi: 10.1073/pnas.1620079114. [PMID: 28484010]
  • Xin Wang, Wei Liu, Changpeng Xin, Yi Zheng, Yanbing Cheng, Su Sun, Runze Li, Xin-Guang Zhu, Susie Y Dai, Peter M Rentzepis, Joshua S Yuan. Enhanced limonene production in cyanobacteria reveals photosynthesis limitations. Proceedings of the National Academy of Sciences of the United States of America. 2016 12; 113(50):14225-14230. doi: 10.1073/pnas.1613340113. [PMID: 27911807]
  • Y Shivani, Y Subhash, Ch Sasikala, Ch V Ramana. Description of 'Candidatus Marispirochaeta associata' and reclassification of Spirochaeta bajacaliforniensis, Spirochaeta smaragdinae and Spirochaeta sinaica to a new genus Sediminispirochaeta gen. nov. as Sediminispirochaeta bajacaliforniensis comb. nov., Sediminispirochaeta smaragdinae comb. nov. and Sediminispirochaeta sinaica comb. nov. International journal of systematic and evolutionary microbiology. 2016 Dec; 66(12):5485-5492. doi: 10.1099/ijsem.0.001545. [PMID: 27902269]
  • Chen Yang, Xiang Gao, Yu Jiang, Bingbing Sun, Fang Gao, Sheng Yang. Synergy between methylerythritol phosphate pathway and mevalonate pathway for isoprene production in Escherichia coli. Metabolic engineering. 2016 09; 37(?):79-91. doi: 10.1016/j.ymben.2016.05.003. [PMID: 27174717]
  • Han Zheng, Li Jing, Na Yao, Qing-shan Yang, Hua-sheng Peng, Ye Shen, Lu-qi Huang. [Cloning and expression analysis of 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene (CcDXR1) in Cinnamomum camphora L.) Presl]. Yao xue xue bao = Acta pharmaceutica Sinica. 2016 09; 51(9):1494-501. doi: . [PMID: 29924561]
  • Geoffrey Benn, Marta Bjornson, Haiyan Ke, Amancio De Souza, Edward I Balmond, Jared T Shaw, Katayoon Dehesh. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proceedings of the National Academy of Sciences of the United States of America. 2016 08; 113(31):8855-60. doi: 10.1073/pnas.1602582113. [PMID: 27432993]
  • Alexandre Huchelmann, Mathieu Semir Brahim, Esther Gerber, Denis Tritsch, Thomas J Bach, Andréa Hemmerlin. Farnesol-mediated shift in the metabolic origin of prenyl groups used for protein prenylation in plants. Biochimie. 2016 Aug; 127(?):95-102. doi: 10.1016/j.biochi.2016.04.021. [PMID: 27138105]
  • Agata Lipko, Ewa Swiezewska. Isoprenoid generating systems in plants - A handy toolbox how to assess contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthetic process. Progress in lipid research. 2016 07; 63(?):70-92. doi: 10.1016/j.plipres.2016.04.002. [PMID: 27133788]
  • Bettina K Wölnerhanssen, Lucian Cajacob, Nino Keller, Alison Doody, Jens F Rehfeld, Juergen Drewe, Ralph Peterli, Christoph Beglinger, Anne Christin Meyer-Gerspach. Gut hormone secretion, gastric emptying, and glycemic responses to erythritol and xylitol in lean and obese subjects. American journal of physiology. Endocrinology and metabolism. 2016 Jun; 310(11):E1053-61. doi: 10.1152/ajpendo.00037.2016. [PMID: 27117004]
  • C A Tyler, L Kopit, C Doyle, A O Yu, J Hugenholtz, M L Marco. Polyol production during heterofermentative growth of the plant isolate Lactobacillus florum 2F. Journal of applied microbiology. 2016 May; 120(5):1336-45. doi: 10.1111/jam.13108. [PMID: 26913577]
  • Min Shi, Xiuqin Luo, Guanhua Ju, Leilei Li, Shengxiong Huang, Tong Zhang, Huizhong Wang, Guoyin Kai. Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering. Journal of agricultural and food chemistry. 2016 Mar; 64(12):2523-30. doi: 10.1021/acs.jafc.5b04697. [PMID: 26753746]
  • Mark Lemos, Yanmei Xiao, Marta Bjornson, Jin-Zheng Wang, Derrick Hicks, Amancio de Souza, Chang-Quan Wang, Panyu Yang, Shisong Ma, Savithramma Dinesh-Kumar, Katayoon Dehesh. The plastidial retrograde signal methyl erythritol cyclopyrophosphate is a regulator of salicylic acid and jasmonic acid crosstalk. Journal of experimental botany. 2016 Mar; 67(5):1557-66. doi: 10.1093/jxb/erv550. [PMID: 26733689]
  • Yan Liu, Shi-Hong Luo, Axel Schmidt, Guo-Dong Wang, Gui-Ling Sun, Marcus Grant, Ce Kuang, Min-Jie Yang, Shu-Xi Jing, Chun-Huan Li, Bernd Schneider, Jonathan Gershenzon, Sheng-Hong Li. A Geranylfarnesyl Diphosphate Synthase Provides the Precursor for Sesterterpenoid (C25) Formation in the Glandular Trichomes of the Mint Species Leucosceptrum canum. The Plant cell. 2016 Mar; 28(3):804-22. doi: 10.1105/tpc.15.00715. [PMID: 26941091]
  • D González-Cabanelas, A Hammerbacher, B Raguschke, J Gershenzon, L P Wright. Quantifying the Metabolites of the Methylerythritol 4-Phosphate (MEP) Pathway in Plants and Bacteria by Liquid Chromatography-Triple Quadrupole Mass Spectrometry. Methods in enzymology. 2016; 576(?):225-49. doi: 10.1016/bs.mie.2016.02.025. [PMID: 27480689]
  • Yi Huang, Zhongkang Wang, Shenfang Zha, Yu Wang, Wei Jiang, Yufeng Liao, Zhangyong Song, Zhaoran Qi, Youping Yin. De Novo Transcriptome and Expression Profile Analysis to Reveal Genes and Pathways Potentially Involved in Cantharidin Biosynthesis in the Blister Beetle Mylabris cichorii. PloS one. 2016; 11(1):e0146953. doi: 10.1371/journal.pone.0146953. [PMID: 26752526]
  • Mi Jung Kim, Jingjing Jin, Junshi Zheng, Limsoon Wong, Nam-Hai Chua, In-Cheol Jang. Comparative Transcriptomics Unravel Biochemical Specialization of Leaf Tissues of Stevia for Diterpenoid Production. Plant physiology. 2015 Dec; 169(4):2462-80. doi: 10.1104/pp.15.01353. [PMID: 26438788]
  • Yu-ru Tong, Ping Su, Meng Zhang, Yu-jun Zhao, Xiu-juan Wang, Wei Gao, Lu-qi Huang. [Cloning and expression analysis of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene in Tripterygium wilfordii]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2015 Nov; 40(22):4378-83. doi: ". [PMID: 27097410]
  • Yair Cárdenas-Conejo, Víctor Carballo-Uicab, Meric Lieberman, Margarita Aguilar-Espinosa, Luca Comai, Renata Rivera-Madrid. De novo transcriptome sequencing in Bixa orellana to identify genes involved in methylerythritol phosphate, carotenoid and bixin biosynthesis. BMC genomics. 2015 Oct; 16(?):877. doi: 10.1186/s12864-015-2065-4. [PMID: 26511010]
  • E Jacqz-Aigrain, B Kassai, C Cornu, J-M Cazaubiel, B Housez, M Cazaubiel, J-M Prével, M Bell, A Boileau, P de Cock. Gastrointestinal tolerance of erythritol-containing beverage in young children: a double-blind, randomised controlled trial. European journal of clinical nutrition. 2015 Jun; 69(6):746-51. doi: 10.1038/ejcn.2015.4. [PMID: 25744158]
  • Manuel Rodríguez-Concepción, Albert Boronat. Breaking new ground in the regulation of the early steps of plant isoprenoid biosynthesis. Current opinion in plant biology. 2015 Jun; 25(?):17-22. doi: 10.1016/j.pbi.2015.04.001. [PMID: 25909859]
  • Justin Walley, Yanmei Xiao, Jin-Zheng Wang, Edward E Baidoo, Jay D Keasling, Zhouxin Shen, Steven P Briggs, Katayoon Dehesh. Plastid-produced interorgannellar stress signal MEcPP potentiates induction of the unfolded protein response in endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 2015 May; 112(19):6212-7. doi: 10.1073/pnas.1504828112. [PMID: 25922532]
  • Alexandra Pokhilko, Jordi Bou-Torrent, Pablo Pulido, Manuel Rodríguez-Concepción, Oliver Ebenhöh. Mathematical modelling of the diurnal regulation of the MEP pathway in Arabidopsis. The New phytologist. 2015 May; 206(3):1075-1085. doi: 10.1111/nph.13258. [PMID: 25598499]
  • Xuhong Du, Chenlu Zhang, Wanli Guo, Weibo Jin, Zongsuo Liang, Xijun Yan, Zhixin Guo, Yan Liu, Dongfeng Yang. Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots. Molecules (Basel, Switzerland). 2015 Apr; 20(5):7574-85. doi: 10.3390/molecules20057574. [PMID: 25919278]
  • J Lv, G S Liu, W Li, Z Hussian, Y H Sun. Cloning and expression analysis of terpenoid metabolism-related gene NsyCMS in Nicotiana sylvestris. Genetics and molecular research : GMR. 2015 Apr; 14(2):3300-8. doi: 10.4238/2015.april.13.9. [PMID: 25966096]
  • Diego González-Cabanelas, Louwrance P Wright, Christian Paetz, Nawaporn Onkokesung, Jonathan Gershenzon, Manuel Rodríguez-Concepción, Michael A Phillips. The diversion of 2-C-methyl-D-erythritol-2,4-cyclodiphosphate from the 2-C-methyl-D-erythritol 4-phosphate pathway to hemiterpene glycosides mediates stress responses in Arabidopsis thaliana. The Plant journal : for cell and molecular biology. 2015 Apr; 82(1):122-37. doi: 10.1111/tpj.12798. [PMID: 25704332]
  • Niels J Nieuwenhuizen, Xiuyin Chen, Mindy Y Wang, Adam J Matich, Ramon Lopez Perez, Andrew C Allan, Sol A Green, Ross G Atkinson. Natural variation in monoterpene synthesis in kiwifruit: transcriptional regulation of terpene synthases by NAC and ETHYLENE-INSENSITIVE3-like transcription factors. Plant physiology. 2015 Apr; 167(4):1243-58. doi: 10.1104/pp.114.254367. [PMID: 25649633]
  • He Chen, Shiwei Chen, Hongli Chen, Yanyan Wu, Guowei Shu. Effects of sugar alcohol and proteins on the survival of Lactobacillus bulgaricus LB6 during freeze drying. Acta scientiarum polonorum. Technologia alimentaria. 2015 Apr; 14(2):117-124. doi: 10.17306/j.afs.2015.2.13. [PMID: 28068009]
  • Shantanu Mandal, Shivangi Upadhyay, Ved Pal Singh, Rupam Kapoor. Enhanced production of steviol glycosides in mycorrhizal plants: a concerted effect of arbuscular mycorrhizal symbiosis on transcription of biosynthetic genes. Plant physiology and biochemistry : PPB. 2015 Apr; 89(?):100-6. doi: 10.1016/j.plaphy.2015.02.010. [PMID: 25734328]
  • Liao Y Chen. Erythritol predicted to inhibit permeation of water and solutes through the conducting pore of P. falciparum aquaporin. Biophysical chemistry. 2015 Mar; 198(?):14-21. doi: 10.1016/j.bpc.2015.01.004. [PMID: 25637890]
  • Wei-Yu Hsieh, Ming-Hsiun Hsieh. The amino-terminal conserved domain of 4-hydroxy-3-methylbut-2-enyl diphosphate reductase is critical for its function in oxygen-evolving photosynthetic organisms. Plant signaling & behavior. 2015; 10(2):e988072. doi: 10.4161/15592324.2014.988072. [PMID: 25723575]
  • Abdellatif Bahaji, Ángela M Sánchez-López, Nuria De Diego, Francisco J Muñoz, Edurne Baroja-Fernández, Jun Li, Adriana Ricarte-Bermejo, Marouane Baslam, Iker Aranjuelo, Goizeder Almagro, Jan F Humplík, Ondřej Novák, Lukáš Spíchal, Karel Doležal, Javier Pozueta-Romero. Plastidic phosphoglucose isomerase is an important determinant of starch accumulation in mesophyll cells, growth, photosynthetic capacity, and biosynthesis of plastidic cytokinins in Arabidopsis. PloS one. 2015; 10(3):e0119641. doi: 10.1371/journal.pone.0119641. [PMID: 25811607]
  • Changquan Wang, Katayoon Dehesh. From retrograde signaling to flowering time. Plant signaling & behavior. 2015; 10(6):e1022012. doi: 10.1080/15592324.2015.1022012. [PMID: 26098376]
  • Thibault Barbier, François Collard, Amaia Zúñiga-Ripa, Ignacio Moriyón, Thibault Godard, Judith Becker, Christoph Wittmann, Emile Van Schaftingen, Jean-Jacques Letesson. Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella. Proceedings of the National Academy of Sciences of the United States of America. 2014 Dec; 111(50):17815-20. doi: 10.1073/pnas.1414622111. [PMID: 25453104]
  • Cinzia Formighieri, Anastasios Melis. Carbon partitioning to the terpenoid biosynthetic pathway enables heterologous β-phellandrene production in Escherichia coli cultures. Archives of microbiology. 2014 Dec; 196(12):853-61. doi: 10.1007/s00203-014-1024-9. [PMID: 25116411]
  • Shefali Singh, Shaifali Pal, Karuna Shanker, Chandan Singh Chanotiya, Madan Mohan Gupta, Upendra Nath Dwivedi, Ajit Kumar Shasany. Sterol partitioning by HMGR and DXR for routing intermediates toward withanolide biosynthesis. Physiologia plantarum. 2014 Dec; 152(4):617-33. doi: 10.1111/ppl.12213. [PMID: 24749735]
  • Isabel Mendoza-Poudereux, Jesús Muñoz-Bertomeu, Isabel Arrillaga, Juan Segura. Deoxyxylulose 5-phosphate reductoisomerase is not a rate-determining enzyme for essential oil production in spike lavender. Journal of plant physiology. 2014 Nov; 171(17):1564-70. doi: 10.1016/j.jplph.2014.07.012. [PMID: 25151124]
  • Mouadh Chebbi, Olivia Ginis, Vincent Courdavault, Gaëlle Glévarec, Arnaud Lanoue, Marc Clastre, Nicolas Papon, Cécile Gaillard, Rossitza Atanassova, Benoit St-Pierre, Nathalie Giglioli-Guivarc'h, Martine Courtois, Audrey Oudin. ZCT1 and ZCT2 transcription factors repress the activity of a gene promoter from the methyl erythritol phosphate pathway in Madagascar periwinkle cells. Journal of plant physiology. 2014 Oct; 171(16):1510-3. doi: 10.1016/j.jplph.2014.07.004. [PMID: 25108262]
  • Sergiy G Krasutsky, Marek Urbansky, Chad E Davis, Christian Lherbet, Robert M Coates, C Dale Poulter. Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. The Journal of organic chemistry. 2014 Oct; 79(19):9170-8. doi: 10.1021/jo501529k. [PMID: 25184438]
  • Hiroshi Kiyota, Yukiko Okuda, Michiho Ito, Masami Yokota Hirai, Masahiko Ikeuchi. Engineering of cyanobacteria for the photosynthetic production of limonene from CO2. Journal of biotechnology. 2014 Sep; 185(?):1-7. doi: 10.1016/j.jbiotec.2014.05.025. [PMID: 24905149]
  • Montserrat Saladié, Louwrance P Wright, Jordi Garcia-Mas, Manuel Rodriguez-Concepcion, Michael A Phillips. The 2-C-methylerythritol 4-phosphate pathway in melon is regulated by specialized isoforms for the first and last steps. Journal of experimental botany. 2014 Sep; 65(17):5077-92. doi: 10.1093/jxb/eru275. [PMID: 25013119]