N-acetylneuraminate (BioDeep_00000001628)

Main id: BioDeep_00000260987

Secondary id: BioDeep_00000014329

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


(4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2, 3-trihydroxypropyl]oxane-2-carboxylic acid

化学式: C11H19NO9 (309.1059764)
中文名称: N-乙酰神经氨酸, 乙酰神经氨酸
谱图信息: 最多检出来源 () 0%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

N-acetylneuraminate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/n-acetylneuraminate (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000001628). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)O
InChI: InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)

描述信息

Acquisition and generation of the data is financially supported in part by CREST/JST.
KEIO_ID A018; [MS2] KO008824
KEIO_ID A018
N-Acetylneuraminic acid is a sialic acid monosaccharide ubiquitous on cell membrane glycoproteins and glycolipids of mammalian cell ganglioglycerides, which plays a biological role in neurotransmission, leukocyte vasodilation, and viral or bacterial infection.

同义名列表

11 个代谢物同义名

(4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2, 3-trihydroxypropyl]oxane-2-carboxylic acid; (4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid; 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid; Neuraminic acid, N-acetyl-; N-Acetyl-neuraminic acid; N-Acetylneuraminic acid; N-Acetylneuraminate; Neu5ac; N-Acetylneuraminic acid; NANA; Lactaminic acid



数据库引用编号

41 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(6)

BioCyc(0)

PlantCyc(0)

代谢反应

14 个相关的代谢反应过程信息。

Reactome(10)

BioCyc(3)

WikiPathways(0)

Plant Reactome(0)

INOH(1)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

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  • Ricardo Zamudio Cañas, María Eugenia Jaramillo Flores, Verónica Vallejo Ruiz, Raúl Jacobo Delgado Macuil, Valentín López Gayou. Detection of Sialic Acid to Differentiate Cervical Cancer Cell Lines Using a Sambucus nigra Lectin Biosensor. Biosensors. 2024 Jan; 14(1):. doi: 10.3390/bios14010034. [PMID: 38248411]
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  • Dileknur Topaloglu, Ismet Burcu Turkyilmaz, Refiye Yanardag. Gastroprotective effect of vitamin U in D-galactosamine-induced hepatotoxicity. Journal of biochemical and molecular toxicology. 2022 Sep; 36(9):e23124. doi: 10.1002/jbt.23124. [PMID: 35670011]
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  • Lauren Byrd-Leotis, Nan Jia, Yasuyuki Matsumoto, Dongli Lu, Yoshihiro Kawaoka, David A Steinhauer, Richard D Cummings. Sialylated and sulfated N-Glycans in MDCK and engineered MDCK cells for influenza virus studies. Scientific reports. 2022 07; 12(1):12757. doi: 10.1038/s41598-022-16605-5. [PMID: 35882911]
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  • Lieh-Bang Liou, Ting-Yi Wang, I-Ju Liu, Han-Chung Wu, Po-Yuan Ke, Yao-Fan Fang, Yen-Fu Chen. α-2,6-sialic acid/IgG anti-dsDNA ratios correlate with human lupus disease activity and possible mechanisms: A pilot study. Lupus. 2022 Jul; 31(8):927-938. doi: 10.1177/09612033221099766. [PMID: 35531921]
  • Hongbing Liu, Dongdong Liu, Muse Ji, Peifu Xiao, Yi Qin, Jiansong Zhao, Na Wang, Jingxin Gou, Tian Yin, Haibing He, Guoliang Chen, Yu Zhang, Xing Tang. Inflammation-targeted sialic acid-dexamethasone conjugates for reducing the side effects of glucocorticoids. International journal of pharmaceutics. 2022 Jun; 622(?):121900. doi: 10.1016/j.ijpharm.2022.121900. [PMID: 35690305]
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