Fenhexamid (BioDeep_00000001574)
Secondary id: BioDeep_00000397807
human metabolite blood metabolite
代谢物信息卡片
N-(2,3-Dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide
化学式: C14H17Cl2NO2 (301.06362820000004)
中文名称: 甲醇中环酰菌胺溶液
谱图信息:
最多检出来源 Homo sapiens(blood) 88.24%
分子结构信息
SMILES: CC1(C(=O)Nc2ccc(O)c(Cl)c2Cl)CCCCC1
InChI: InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:81853
- KEGG: C18593
- PubChem: 213031
- HMDB: HMDB0252201
- Metlin: METLIN72394
- ChEMBL: CHEMBL1688541
- chemspider: 184726
- CAS: 126833-17-8
- PMhub: MS000000790
- PubChem: 124489267
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Da-Woon Jung, Da-Hyun Jeong, Hee-Seok Lee. Stimulation of estrogen receptor-alpha by hydroxyanilide fungicide, fenhexamid promotes lipid accumulation in 3 T3-L1 adipocyte.
Pesticide biochemistry and physiology.
2024 Feb; 199(?):105757. doi:
10.1016/j.pestbp.2023.105757. [PMID: 38458660] - Stephen Boushell, Mengjun Hu. Post-Infection Application of Fenhexamid at Lower Doses in Conjunction with Captan Slowed Fungicide Resistance Selection in Botrytis cinerea on Detached Grape Berries.
Phytopathology.
2023 Aug; ?(?):. doi:
10.1094/phyto-04-23-0141-r. [PMID: 37606323] - Leonie Hillebrands, Marc Lamshoeft, Andreas Lagojda, Andreas Stork, Oliver Kayser. In vitro metabolism of tebuconazole, flurtamone, fenhexamid, metalaxyl-M and spirodiclofen in Cannabis sativa L. (hemp) callus cultures.
Pest management science.
2021 Dec; 77(12):5356-5366. doi:
10.1002/ps.6575. [PMID: 34309997] - S A Alzohairy, J Gillett, S Saito, R N Naegele, C L Xiao, T D Miles. Fungicide Resistance Profiles of Botrytis cinerea Isolates From Michigan Vineyards and Development of a TaqMan Assay for Detection of Fenhexamid Resistance.
Plant disease.
2021 Feb; 105(2):285-294. doi:
10.1094/pdis-05-20-1087-re. [PMID: 32762329] - Zivile Luksiene, Neringa Rasiukeviciute, Bernadeta Zudyte, Nobertas Uselis. Innovative approach to sunlight activated biofungicides for strawberry crop protection: ZnO nanoparticles.
Journal of photochemistry and photobiology. B, Biology.
2020 Jan; 203(?):111656. doi:
10.1016/j.jphotobiol.2019.111656. [PMID: 31676121] - A Amiri, A I Zuniga, N A Peres. Potential Impact of Populations Drift on Botrytis Occurrence and Resistance to Multi- and Single-Site Fungicides in Florida Southern Highbush Blueberry Fields.
Plant disease.
2018 11; 102(11):2142-2148. doi:
10.1094/pdis-11-17-1810-re. [PMID: 30169135] - Jie-Hua Shi, Yan-Yue Lou, Kai-Li Zhou, Dong-Qi Pan. Elucidation of intermolecular interaction of bovine serum albumin with Fenhexamid: A biophysical prospect.
Journal of photochemistry and photobiology. B, Biology.
2018 Mar; 180(?):125-133. doi:
10.1016/j.jphotobiol.2018.01.025. [PMID: 29413695] - Kim Christopher Cohrs, Joachim Burbank, Julia Schumacher. A new transformant selection system for the gray mold fungus Botrytis cinerea based on the expression of fenhexamid-insensitive ERG27 variants.
Fungal genetics and biology : FG & B.
2017 03; 100(?):42-51. doi:
10.1016/j.fgb.2017.02.001. [PMID: 28188884] - Facundo Rivera-Becerril, Diederik van Tuinen, Odile Chatagnier, Nadine Rouard, Jérémie Béguet, Catherine Kuszala, Guy Soulas, Vivienne Gianinazzi-Pearson, Fabrice Martin-Laurent. Impact of a pesticide cocktail (fenhexamid, folpel, deltamethrin) on the abundance of Glomeromycota in two agricultural soils.
The Science of the total environment.
2017 Jan; 577(?):84-93. doi:
10.1016/j.scitotenv.2016.10.098. [PMID: 27817923] - Dafang Yin, Sisi Wu, Na Liu, Yanni Yin, Zhonghua Ma. The natural fenhexamid-resistant grey mould populations from strawberry in Zhejiang Province are dominated by Botrytis cinerea group S.
Pest management science.
2016 Aug; 72(8):1540-8. doi:
10.1002/ps.4183. [PMID: 26537826] - Danièle Debieu, Jocelyne Bach, Emeline Montesinos, Sabine Fillinger, Pierre Leroux. Role of sterol 3-ketoreductase sensitivity in susceptibility to the fungicide fenhexamid in Botrytis cinerea and other phytopathogenic fungi.
Pest management science.
2013 May; 69(5):642-51. doi:
10.1002/ps.3418. [PMID: 23139232] - Jieru Fan, Martin Urban, Josie E Parker, Helen C Brewer, Steven L Kelly, Kim E Hammond-Kosack, Bart A Fraaije, Xili Liu, Hans J Cools. Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function.
The New phytologist.
2013 May; 198(3):821-835. doi:
10.1111/nph.12193. [PMID: 23442154] - Pierre Leroux, Michel Gredt, Florent Remuson, Annie Micoud, Anne-Sophie Walker. Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
Pest management science.
2013 Jan; 69(1):15-26. doi:
10.1002/ps.3408. [PMID: 23073993] - Thomas Veloukas, George S Karaoglanidis. Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
Pest management science.
2012 Jun; 68(6):858-64. doi:
10.1002/ps.3241. [PMID: 22262495] - Éva Fekete, Erzsébet Fekete, László Irinyi, Levente Karaffa, Mariann Árnyasi, Mojtaba Asadollahi, Erzsébet Sándor. Genetic diversity of a Botrytis cinerea cryptic species complex in Hungary.
Microbiological research.
2012 May; 167(5):283-91. doi:
10.1016/j.micres.2011.10.006. [PMID: 22130648] - Alexis Billard, Sabine Fillinger, Pierre Leroux, Hélène Lachaise, Roland Beffa, Danièle Debieu. Strong resistance to the fungicide fenhexamid entails a fitness cost in Botrytis cinerea, as shown by comparisons of isogenic strains.
Pest management science.
2012 May; 68(5):684-91. doi:
10.1002/ps.2312. [PMID: 22045588] - A Billard, V Laval, S Fillinger, P Leroux, H Lachaise, R Beffa, D Debieu. The allele-specific probe and primer amplification assay, a new real-time PCR method for fine quantification of single-nucleotide polymorphisms in pooled DNA.
Applied and environmental microbiology.
2012 Feb; 78(4):1063-8. doi:
10.1128/aem.06957-11. [PMID: 22156413] - Domenico Zocco, Ingrid M Van Aarle, Elodie Oger, Luisa Lanfranco, Stéphane Declerck. Fenpropimorph and fenhexamid impact phosphorus translocation by arbuscular mycorrhizal fungi.
Mycorrhiza.
2011 Jul; 21(5):363-374. doi:
10.1007/s00572-010-0344-0. [PMID: 21085999] - Estelle Campagnac, Anissa Lounès-Hadj Sahraoui, Djouher Debiane, Joël Fontaine, Frédéric Laruelle, Guillaume Garçon, Anthony Verdin, Roger Durand, Pirouz Shirali, Anne Grandmougin-Ferjani. Arbuscular mycorrhiza partially protect chicory roots against oxidative stress induced by two fungicides, fenpropimorph and fenhexamid.
Mycorrhiza.
2010 Mar; 20(3):167-78. doi:
10.1007/s00572-009-0267-9. [PMID: 19756779] - Matthias Kretschmer, Michaela Leroch, Andreas Mosbach, Anne-Sophie Walker, Sabine Fillinger, Dennis Mernke, Henk-Jan Schoonbeek, Jean-Marc Pradier, Pierre Leroux, Maarten A De Waard, Matthias Hahn. Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea.
PLoS pathogens.
2009 Dec; 5(12):e1000696. doi:
10.1371/journal.ppat.1000696. [PMID: 20019793] - Josep V Mercader, Antonio Abad-Fuentes. Monoclonal antibody generation and direct competitive enzyme-linked immunosorbent assay evaluation for the analysis of the fungicide fenhexamid in must and wine.
Journal of agricultural and food chemistry.
2009 Jun; 57(12):5129-35. doi:
10.1021/jf900867u. [PMID: 19530708] - Anne-Noëlle Petit, Geneviève Wojnarowiez, Marie-Laure Panon, Fabienne Baillieul, Christophe Clément, Florence Fontaine, Nathalie Vaillant-Gaveau. Botryticides affect grapevine leaf photosynthesis without inducing defense mechanisms.
Planta.
2009 Feb; 229(3):497-506. doi:
10.1007/s00425-008-0849-3. [PMID: 19002490] - Estelle Campagnac, Joël Fontaine, Anissa Lounès-Hadj Sahraoui, Frédéric Laruelle, Roger Durand, Anne Grandmougin-Ferjani. Differential effects of fenpropimorph and fenhexamid, two sterol biosynthesis inhibitor fungicides, on arbuscular mycorrhizal development and sterol metabolism in carrot roots.
Phytochemistry.
2008 Dec; 69(17):2912-9. doi:
10.1016/j.phytochem.2008.09.009. [PMID: 19007946] - Sabine Fillinger, Pierre Leroux, Christiane Auclair, Christian Barreau, Charbel Al Hajj, Danièle Debieu. Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
Antimicrobial agents and chemotherapy.
2008 Nov; 52(11):3933-40. doi:
10.1128/aac.00615-08. [PMID: 18779358] - Domenico Zocco, Joel Fontaine, Evgenia Lozanova, Laurent Renard, Céline Bivort, Roger Durand, Anne Grandmougin-Ferjani, Stéphane Declerck. Effects of two sterol biosynthesis inhibitor fungicides (fenpropimorph and fenhexamid) on the development of an arbuscular mycorrhizal fungus.
Mycological research.
2008 May; 112(Pt 5):592-601. doi:
10.1016/j.mycres.2007.11.010. [PMID: 18396024] - D T Likas, N G Tsiropoulos, G E Miliadis. Rapid gas chromatographic method for the determination of famoxadone, trifloxystrobin and fenhexamid residues in tomato, grape and wine samples.
Journal of chromatography. A.
2007 May; 1150(1-2):208-14. doi:
10.1016/j.chroma.2006.08.041. [PMID: 16950327] - N Bellí, S Marín, V Sanchis, A J Ramos. Impact of fungicides on Aspergillus carbonarius growth and ochratoxin A production on synthetic grape-like medium and on grapes.
Food additives and contaminants.
2006 Oct; 23(10):1021-9. doi:
10.1080/02652030600778702. [PMID: 16982524] - Claudia Metz, E C Oerke, H W Dehne. Biological control of grey mould (Botrytis cinerea) with the antagonist Ulocladium atrum.
Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen).
2002; 67(2):353-9. doi:
". [PMID: 12701443] - D Debieu, J Bach, M Hugon, C Malosse, P Leroux. The hydroxyanilide fenhexamid, a new sterol biosynthesis inhibitor fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea).
Pest management science.
2001 Nov; 57(11):1060-7. doi:
10.1002/ps.394. [PMID: 11721524]